LOCUS       c00087_gnlPro..        16721 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DKBDKLKA_87.
ACCESSION   c00087_gnlPro..
VERSION     c00087_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 23:57:47
            Original ID  :: gnl|Prokka|DKBDKLKA_87
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16721
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16721
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[9912:13470](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(9913..13470)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16721
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16721
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             254..1480
                     /locus_tag="ctg87_1"
                     /transl_table=11
                     /translation="MFFFLIVPLFLALFYKPIAYLCGRFLNNKSKRENYFMKHISNFLR
                     SKSWNVFLFLYLALPLFAQKEYKIDQVSVVNVGDGRLLFQELKTEKALNGEHRIIDGYH
                     SAYVLASFKDGFYDGGYKEYVDNILITEGSYKEGRKDGLFKINSKFDGKLKEEKSYKEG
                     KLDGTSKSYFTTGKVESERNFRMGKEHGKQLSYESDGTLRKEHNYKDGKQVGKQYTFLK
                     GTYDLYETVYFNEEGFQDGEYSSVFTFGSPRILGSYKNGKKNGRWTTFAESGDTLMIET
                     YLDGKEDGLHVSFANGSGVRQKEYYMKNDRKDGLYREYNLENGELRYEATYQAGRLHGK
                     ERRLIVSNRFDYWETSTYVNGRQNGPFEARYVKNDQLRECGEYKNGHRVGRWKRYTIDG
                     KLEKEWDEN"
     CDS             1813..4566
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 64.3; E-value: 4.2e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg87_2"
                     /sec_met_domain="Peripla_BP_1 (E-value: 7.4e-21, bitscore:
                     64.3, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTMRYLKWMLVLFGLIGMTACRQDTPRFRIGVAQCSDDSWRHKM
                     NDEILREAMFYNGVSVEIRSAGDDNSKQAEDVHYFMDEGVDLLIISANEAAPMTPIVEE
                     AYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGLSGST
                     PAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRRHPKIDAVYAHNDRIA
                     PGAYQAAKMAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQLAMDI
                     LEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVATQQVV
                     LYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDKLEEQRDQLIQLSHQ
                     LEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADKTLSGDQHRMLMLIQRNVNILLR
                     LVNQILDFRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDSMPDTDYHT
                     LADMEKLERIYFNLLSNAFKFTPENGKIAVRLSSLSKEDKRWIRFTVANTGSMISAEHI
                     RNVFDRFYKIDMHHTGSGIGLALVKAFVEMHGGMISVESDEKQGTVFTVELPVQSCEAV
                     AAEPDTTLVSADSRTTDVLLAEEEELEKGYDSSKPSVLIIDDNEDIRSYVHTLLHTDYT
                     VIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLTACSL
                     DEQRIQGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDK
                     DFVERFKSLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKA
                     ASLLASSDMTVAEIGYEVGFSSPSYFAKCYKEQFGESPTDFLKRKG"
     CDS             4594..4926
                     /locus_tag="ctg87_3"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGAPQ
                     CSRMVGRALKEVPDELSIPCHRVVNSTGRLVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(4889..6175)
                     /locus_tag="ctg87_4"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFIRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RYFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFMAIFTLPQQFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLLIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVTMGIVLLALPLIKIAPADLLPYYEEWCHSLAVHQSAGAYDSFFYARP
                     IAAWTLPHFRALQIGMLGLLTLLFLGNFRKWSSFAFRAQALGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTATDKILFWCCFVLLCIVPIDIFVPIPIRDFITRTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             6648..7874
                     /locus_tag="ctg87_5"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKGEREQKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             7871..8701
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg87_6"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.9e-29, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             8729..9589
                     /locus_tag="ctg87_7"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVVPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNTESIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPEKD"
     CDS             complement(9600..9788)
                     /locus_tag="ctg87_8"
                     /transl_table=11
                     /translation="MIGFVIWIIGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(9913..13470)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg87_9"
                     /sec_met_domain="PFOR_II (E-value: 5e-19, bitscore: 58.2,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 7.1e-83, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 7.8e-32, bitscore: 100.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-12, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.5e-12, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.6e-08, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.5e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.2e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKSIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIISVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIAMEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTMNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIASDCCPAEYKEVFAEWINNMLDAEKTKE
                     LAEKIIPMVEAAKDKCNHCKQIADLQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKW
                     RYNSYKRLARENWGADTAE"
     CDS             complement(13504..14709)
                     /locus_tag="ctg87_10"
                     /transl_table=11
                     /translation="LPAEKQRNEMESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGI
                     KGTRGVGKTTFLLQYAKEKFGTDRSCLFINMNNFYFSGHSLVDFANEFQKRGGKVLLID
                     QVFKHPEWSKELRMCYDRFPSLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREFL
                     NLQTGMKFRAYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENL
                     LKTMNMMVEVDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDVQTSRATVMN
                     YIKYLADARLINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFVNTLW
                     KDHKVHKGDKNVSFMVDEVMPFKICAEGTKIKNNPDVTYALQKAEIGRGNQIPLWMFGF
                     LY"
     CDS             14889..16043
                     /locus_tag="ctg87_11"
                     /transl_table=11
                     /translation="MALASGETNYMAPASARQMASDLALLPMWYAEAGSAVLAPSAYNA
                     DFLKTKSELLGMDVALLTEPEVADGKDRKFSPWGWDPALRKRLMTLGADQTELPSADYM
                     NILREHSHRLQAVKLLPGLRLNEYFCGESFYLSTLAECSAFVEGREACLLKAPLSGSGK
                     GLNWCKGIFTTFISGWCARVAASQGGVVGEPIYNKVEDFAMEFYADGRGRVVFAGYSVF
                     HTGGSGMYAGNDLLSDEKILQKLSAYVPQEEFIRLRTRLEEELSALFGGFYHGYLGVDM
                     MICHFPDEAPVYRIHPCVEINLRMNMGVVAWLLTDRYLAADAEGVFRIDYYPLAGQALE
                     EHRQMSASFPLSVENNRVCAGYLPLVPVTPQSRYRAFLLLTLPQ"
ORIGIN
        1 aagactagtg tcaaagttag ttcactgcaa ctctactttt caaatataca cttatatttt
       61 gttgtgatat ttaatactgc aaatgtaaat gtgtcaaaag tcaaaagtaa ctaaactctc
      121 ctccttcctg aaggagggga atttagttgc ttttgacaca tcttcttttc tgtttcttat
      181 ttcagtaaat gtcccccttc cctgtgtttt gatttactac ttaatctgtt aattattaga
      241 atgataataa cagatgttct tttttctaat tgtccccctc tttcttgcct tgttttataa
      301 gccgattgcc tatctttgcg gcaggttttt aaataataaa tcaaaaagag aaaactactt
      361 tatgaaacac atttcgaact tcctcagatc aaaaagctgg aacgtatttt tgtttttata
      421 tcttgctctt cctttgtttg cgcaaaagga atataagatc gatcaggtat ctgttgttaa
      481 tgtaggcgat ggcagactgt tgtttcagga actgaaaacg gaaaaagcat tgaatggcga
      541 acatcgcatc atagatggtt atcattccgc ctatgtgctg gcatctttta aagatggttt
      601 ttatgatggc ggatacaaag aatatgtgga caatatatta ataacggaag gaagttataa
      661 agaagggcgg aaggatggcc tcttcaagat taactccaag tttgacggta agctgaaaga
      721 agaaaagtcc tataaggaag gtaagctgga cggtacgagc aaaagttact ttactaccgg
      781 aaaagtggaa agtgaaagaa acttccggat ggggaaagag cacgggaagc aactgtcgta
      841 cgaatctgac ggtactttgc ggaaagagca taattacaag gacgggaagc aggtaggcaa
      901 acagtatact tttctgaaag gtacatatga tttgtatgag accgtttatt tcaatgaaga
      961 aggttttcag gacggtgaat attcgtccgt gtttacgttt ggctcgccac gtatactggg
     1021 tagttataag aatggaaaga agaatggtcg ttggactact tttgctgaaa gcggagatac
     1081 gctgatgatt gaaacctatc tggatggaaa agaagatgga ctccatgtct catttgccaa
     1141 cggaagtggg gtaaggcaga aagaatatta tatgaagaac gatcgtaaag acggtttata
     1201 ccgtgaatat aatttggaaa atggtgaatt gagatatgaa gctacctatc aggccggcag
     1261 attgcatggc aaggaacgac ggctgatagt gagcaaccgc tttgattatt gggaaacttc
     1321 tacctatgtg aacggaaggc agaacggacc gttcgaagct cgttatgtaa agaatgacca
     1381 gcttcgtgaa tgtggggaat ataagaatgg tcaccgtgta ggacgatgga aacgctacac
     1441 tattgatggt aaactggaaa aggaatggga tgaaaactaa ccggtagatg aaaggtcaga
     1501 gcataaaaaa aggagcaacg ccttgctcca acctttgtta accttaaatc taatactatg
     1561 aaaaacacag tgcaaagata cggacttctg tgaaatctgc aaattatcca agtaaaacgc
     1621 tatgttttat aacattgatt aagtgtttgt tttacgcttt atacttttgt taatactttc
     1681 cgatggtctg aaagaggact gctttccttc tttttagaat aataaatagc tgaagttaga
     1741 gaactttaca gtattatttc ttatttttgt tcttaattgg attacagaaa gaactatgaa
     1801 atgatgagat ggatgaagac gatgagatat ctgaagtgga tgctggtgct gtttggttta
     1861 atcgggatga cggcttgccg gcaggataca ccccgttttc gtattggggt ggctcaatgc
     1921 agcgatgatt catggcgaca taagatgaat gatgagattc ttcgggaagc gatgttttat
     1981 aatggtgttt cggtggaaat ccgttcggca ggggatgata acagtaagca ggcggaagat
     2041 gtccattatt ttatggacga aggagtcgat ctgctgatta tttccgctaa cgaagctgct
     2101 cctatgactc cgattgtaga agaagcttat cagaaaggca tccccgttat tcttgtagac
     2161 cggaagattc tttcggataa atatactgcc tatatcggag ccgataatta tgaaatcggt
     2221 cgttcggtag gaaactatat tgcctccagt ctgaaaggga agggaaatat agtagaactg
     2281 acaggattga gcggttcgac tcctgcaatg gaacggcatc agggatttat ggctgccatc
     2341 agtaaattcc cggatataaa gctgattgat aaagcggatg ctgcgtggga acgtggtccg
     2401 gcagagatag aaatggatag tatgcttcgg aggcatccta agattgatgc tgtgtatgcc
     2461 cataatgacc gtatcgctcc gggtgcctat caggcagcaa agatggcagg gcgggagaag
     2521 gaaatgattt ttgtcggcat agatgccttg ccgggtaagg gaaacggact ggaactggta
     2581 ctggacagtg tgctggatgc cacctttatc tatccgacca atggcgataa ggtactgcaa
     2641 ctggctatgg acattctgga gaagaaaccc tatcccaaag aaacggtgat gaataccgct
     2701 gttgtggacc gtaccaacgc acacgtcatg cagttgcaga ccacacacat ttccgaactc
     2761 gacaaaaaga ttgaaacgct caacggacgt atcggtggct atctctctca ggtagctaca
     2821 caacaggtcg ttttatacgg cagtctgatt atccttttat tggtagccgg cttattattg
     2881 gtcgtttata aatcactccg ctctaagaat cgcttgaata aagagctttt taagcagaag
     2941 cagcaattgg aagagcagcg tgacaaactg gaagaacagc gtgaccaatt gatacagctc
     3001 tctcatcaac tggaagaagc tacccatgcc aagctggtct ttttcaccaa tatttctcac
     3061 gacttccgta ctccgttgac attggttgcc gacccggtag aacatttgtt ggcggacaag
     3121 acactgagcg gagatcagca ccggatgctc atgctgattc agcggaatgt gaacattctt
     3181 ctgcgtctgg tcaatcagat tctggatttc cgtaaatatg aaaacggcaa gatggaatat
     3241 actccggtta cggtggatgt cctttcttct ttcgaaggat ggaatgagtc ttttcaggcg
     3301 gcagcccgta agaagcatat ccatttttct tttgatagta tgccggatac ggattatcat
     3361 acactggcag acatggagaa gctggaacgt atttatttca atcttctgtc caatgccttt
     3421 aagtttacac cggaaaacgg gaaaatagcc gtccgtctgt cttcccttag taaagaggac
     3481 aagcgatgga tacgtttcac ggtggcaaat accggttcta tgatttctgc cgaacatatt
     3541 cgcaatgtat tcgaccgttt ctataagatc gatatgcacc ataccggttc gggaatcgga
     3601 ctggcattgg taaaagcctt cgtagaaatg cacggtggta tgatctccgt agagagcgat
     3661 gagaaacagg gcacggtctt taccgttgaa ctgcctgtac agtcttgtga ggctgttgct
     3721 gccgaaccgg ataccaccct tgtttctgcg gattcccgta caacagatgt tctattggcg
     3781 gaagaggaag aactggaaaa aggatatgac tcttccaaac cgtccgtact gattattgat
     3841 gataatgagg atatccgttc gtatgtccat acgttgttgc atacagacta tacggtgatt
     3901 gaagcggcag acggctccga aggaatccgt aaggctatga agtatgttcc ggacctgatc
     3961 atttctgatg tgatgatgcc gggcattgat ggcattgaat gttgccgccg gctgaaaagt
     4021 gagttacaga cctgtcatat tccggttatt ctgctgacag cgtgttcact ggacgaacag
     4081 cgtattcagg gatatgacgg tggtgcggat tcttatattt caaagccgtt cagttcacag
     4141 ctgttgctgg cacgtgtccg caatctgatc gattctcacc gtcgtctgaa acagttcttt
     4201 ggtgacgggc agacattggc aaaagaagat gtctgcgata tggacaagga ttttgtagaa
     4261 agattcaagt cattgattga agagaaaatg ggagactccg gtttgaatgt ggaggacttg
     4321 ggcaaagaca tgggactaag ccgtgtgcag ctttatcgca agattaaatc attgactaac
     4381 tactctccga atgaattgct ccgtatcgcc cgtttgaaga aggcagcttc tttgcttgct
     4441 tcttcggaca tgaccgtagc ggagattggt tatgaagtcg gtttcagttc accttcttat
     4501 ttcgccaagt gctataaaga gcagtttgga gagagcccga cagatttcct gaaaaggaaa
     4561 ggatgatttc attgatatcg taaagaggga tatatgaaag attataaagt agataaagag
     4621 agcttttccg aatcctttcg gaaggaagtg tacgaagtcg tatcccagat acctgtggga
     4681 aaagtatcta cttatggagg tattgctttg ctgttggggg caccccaatg ctcgcggatg
     4741 gtgggacgtg cattgaaaga agtgccggat gaattatcca ttccctgcca tagagttgta
     4801 aattccaccg gaaggctggt gcccggttgg gtggaacaaa aacaactctt gctggcagaa
     4861 gaagtttctt tcaaagctaa cggatgcgtt aatctgaaag aacatttgtg gcacgtggat
     4921 gaatgaagga tgcaaggaag gtaagccata tcatccgtat ccatacaata aagaaaaccc
     4981 atacatgaag ccataaggtc ctggtaatga aatctctgat gggtataggg acgaatatgt
     5041 cgataggaac gatacataac agcacaaaac agcaccaaaa tagaatcttg tctgttgcgg
     5101 tacgtgttgg tctgctccaa taccagagca tgaaacctgc caatgcgata atataggtat
     5161 gcttctcggc ggagtcactc agtaatacta cccagcccat gagaatgccc aaagcctggg
     5221 cacggaaggc aaaagacgac catttgcgga aattccccaa aaagagcaga gtcagcaagc
     5281 cgagcattcc tatctgaagt gcacggaagt gtggcaatgt ccatgctgca atggggcggg
     5341 catagaaaaa tgaatcataa gctccggcgg actgatgaac agcaagacta tggcaccatt
     5401 cttcataata ggggagcaaa tctgcaggag ctattttgat taacggtaat gcaagcaata
     5461 caatgcccat tgtaacggca tagccaaagt tacgccatac gtgaggatag cacagcaaca
     5521 atgccagttc gaaaattcca tatactttgg tacatcccga aatcatgatt aacagaacag
     5581 ccagaaatcc acggtctttt tccaataacg tataggcgaa taagaataaa taggctaccg
     5641 ttatgttata ctgaaatgaa agtaaacttt gtcctaaaat cagtaacaga aaaaggaaca
     5701 tacggcattt ctgctgctgg gtgaattgtt ggggcagcgt gaagatcgcc ataaagaaca
     5761 gcgaataatt gaatagattc cacgcgaaag gtcccagcca tgcaggcaga tacgcaaacg
     5821 gagcgaacaa taccgtgaaa actggagaat aaaggaagta gcgtccgtga gcttctacaa
     5881 attcagttgt gtatgggctg atgccttgcc agaagaattg agtagcgtcc gagaagacca
     5941 taaagttttg atgccgtcct cgtataaatt cgagcagagt cactataaaa gcgagcagga
     6001 aacctatcat gtagagattc cgccggctat agaaaaacgg cattttgggg ttctttttac
     6061 taaggaactg tacttggctt ttgtcgtcta gtgtggcagt acctgtttgt ttttcttttg
     6121 ttgtgtaatg acaattatcc ttccccagga aaattgtaat agccctgttg aacatataaa
     6181 tctagtttag ttattgacgc caaatatacg gtgtttaagt gaaatattca aacttatttt
     6241 atatttatct gccggtttgt tctattttgc tgagtgatag gggaatatta cccggaaact
     6301 ttccatatca ttacaaataa agccctctgt atgccccgga ttttgaatat aatttgtatg
     6361 tttaatccgt tttttgtatc tttgtgccag caagatactg gaacaggctg tttttataca
     6421 taaaaatgct attttttgct attcgttgaa aggattatct tatcaaattc tattcctttt
     6481 ttaattactc agtctgtcaa taatcatttt attaattatt tcgggattca ttgttatttg
     6541 tcccttattt aaatcagaac tttatacgat ataaagaaag attcctgtta tcgtttgttc
     6601 ttgtcttgct gtgtatatta ttttaataac ctaaaccatt ttattgtatg agtaaaatag
     6661 aaattaaaga tctctatctg gtttttggca atgagaagca gaaggctttg aagatgttga
     6721 aagaaggtaa aacaaaaagt gaaatattga aagcgaccgg atgtacagtt gcggtgaaag
     6781 atgcgaatct ttccattaat gaaggcgaaa tattcgtcat tatggggctg tccggtagtg
     6841 gaaagtccac tttactccgc tgcatcaacc gtttgatacg ccctacttcc ggagaagtga
     6901 ttatcaatgg aacagacata gccaaagtgt cggataagga actgttgcag attcgccgga
     6961 aagaactggc tatggtcttt cagaacttcg gtctgcttcc tcaccgttct gtcttgcata
     7021 atatagcttt cgggctcgaa ctacagggag taaaaaaggg agaacgggag cagaaagcga
     7081 tggaaagtat gcaactggtg gggctgaaag gctacgagaa tcagatggta agtgaactgt
     7141 cgggtgggat gcagcagcgt gtcgggctgg cgcgggcttt ggccaataat cccgaagtcc
     7201 tgttgatgga tgaggccttc tcggcactcg atcctttgat ccgtgtgcag atgcaggatg
     7261 aactgctgac tttgcagtcg aagatgaaaa aaacgattgt ctttattact cacgacctga
     7321 gtgaagcgat taaattgggt gaccggattg ctatcatgaa ggatggagaa attgtacaaa
     7381 tcggtacatc ggaagaaatc ctgaccgaac ctgccaacgc ttatgtagaa cgatttgtgg
     7441 agaatgtaga tcgaagcaag attataacag cttcctctgt tatggtagat aaacccatag
     7501 tggcacgttt gaagaaagaa ggcccggagg tgctgatccg taagatgcgc gaacggaatc
     7561 tgaccgttct tccggtagtc gattccaata atctgttagt aggagaggtg cggttgaatg
     7621 acttgctgaa actacgaaaa gagcaaatcc gctccatcga gtccgtagta aggcatgaag
     7681 ttcattcagt gctgggtgat acggtgctgg aagatattct tccgttgatg acaaaaacga
     7741 actcgccaat ctgggtcgta aatgagaatc gggagtttga aggcgtagtg ccactttcct
     7801 cattgatcat cgaagtaacg ggaaaagata aagaagaaat taatgaaatc attcaaaacg
     7861 caatagaatt atgataaata tcggacaata tatagagact gccattaatt ggctcacaga
     7921 acattttgct tccttttttg atgctctcag catggggatc ggaggattca tagacggttt
     7981 tcagcacgta ctgtttggaa taccttttta tatcacaatt gcagtgctgg ctgcgctcgc
     8041 ctggtttaag tcgggtaagg ggacagccgt atttaccctc ttgggtttat tgcttattta
     8101 cggcatgggc ttttgggaag aaacgatgca gacattggca ttggtacttt cttccacttg
     8161 tctggcattg cttttaggcg ttccgttggg aatctggact gccaacagtg atcgttgtaa
     8221 caagataatg cgccctgtcc tcgactttat gcagacaatg cctgcctttg tctatctgat
     8281 tcctgccgtt ctattcttcg gattgggaac tgtgccggga gcttttgcca ccatcatctt
     8341 tgcaatgcct cctgtggttc gtctgaccgg tctgggcatt cgtcaggttc ctaaaaacgt
     8401 agtagaagcc tcccgctctt ttggagctac tccctggcag cttctttata aggtgcaatt
     8461 gcctttggcg ttgcctacta ttctgacggg aatcaaccag acgatcatga tgtcactttc
     8521 gatggtagtg attgctgcca tgatttctgc cggaggattg ggagaaatcg tgctgaaagg
     8581 tatcacccaa atgaaaatcg gactcggatt tgaaggcggt atcgcagtcg tgatattggc
     8641 gatcgtgctg gaccgcatca ctcagggtat ggcagataac agaaaaagta aaaagaaata
     8701 agaatcacac caaagaaagg aataatcaat gaataagata aaaatgattg cggcaatgtt
     8761 tattgccggc atactcttaa ccttcgtttc ctgcggagac aacggaaaga gtaagaagat
     8821 aagtatcgct tatgccaact ggtcggaagg tattgcaatg acaaaccttg ccaaagcgat
     8881 ttttgaagat caggggtacg atgtaaagtt gctgaatgcc gaccttgcac ctatatttac
     8941 ctctatctcc cgtaagaaag cagacgtatt tatggatgtc tggatgcctg tcactatgga
     9001 agattatatg aaacaatacg gggataaact cgaagttatc ggggatattt atgatggtgc
     9061 ccgtatcggg ctggtggttc cggattacgt tacgatcaac tcaatcgaag aactgaacgc
     9121 ggaaaaggaa cgtttctccg gtcagattgt cggtattgat gccggagccg gtattatgaa
     9181 agctaccgat caggccatca aagactatgg attggattat aaactgatga cttcgagcgg
     9241 acctgccatg actgcttccc taaagaaagc gattgataag aaagactgga ttgtcgtgac
     9301 gggatggacg cctcactgga tgttcgaccg tttcaagctg aaagttcttc aggacccgaa
     9361 gctgatatat ggaaatacgg aatccattca taccatagca tggaaaggtt ttagcgagaa
     9421 agaccctttt gctgccgaac ttttgggcaa cattcgtctg acagatgcgg aaatcagctc
     9481 cttaatgact gctctggaag aggcgcagac aacggaaaga caggctgccc gtcaatggat
     9541 ggaagaacat caggaactgg tgaacagttg gattcctgag aaagattgat atgcaaacac
     9601 tacttcaacc atcccgccat tctttcttta ccatagaagt agtagaaaag tagtcccagc
     9661 cagctggtaa gaacgattaa tacaatcgct ataagtcttt tctctacagc cgcatttata
     9721 ttccaaatct ctatggcagc tctgaaagtc agtatcaaac cgataatcca aataacaaat
     9781 ccgatcatat ctttagagtt ttaatgaata tcttcgtgag aagtaatcgt tacttctaag
     9841 atataaacaa aaaaggcagg aatctgtttc caggattcct gccttttatt atgtacaaag
     9901 tatttctact tattattcag ctgtatcagc tccccagttt tctctggcaa gacgtttgta
     9961 gctgttgtaa cgccatttag cgttttcttc agcagcttta aacagttctt cagcttcagc
    10021 aggatattgt ttcattacag aagcgtaacg aacttcaccc ttcaagaaac cttggaagtc
    10081 ttcccagtta ggttctttgc tatccagttg gaacggattc ttgccttctt cttccaaagc
    10141 agggttgtaa cgccacaagt gccagtaacc gcacttaaca gccttttctt cttcttcctg
    10201 gctcttaccc ataccggctt tcagaccgtg gttgatacat ggagcgtaag cgatgatcag
    10261 tgatggtccc ggatatgctt cagcttcacg gatagctttc agagtctgag cctggtcagc
    10321 acccatagca atctgagcaa catatacata accgtaagta gtagccatca gaccgaggtc
    10381 tttcttacgt acacgcttac ctgcagcagc aaacttagcg atagcgccta ccggagtagc
    10441 tttagaagac tgaccacctg tgttagagta aacctcagta tccaatacaa ggatgttaac
    10501 gtccttaccg gaagcgatta catggtcaag accaccgtaa ccgatatcat aagaagcacc
    10561 gtcaccaccg atgatccatt ggctgcgttt aacaagatat tgttgcagat cagcgatttg
    10621 cttgcagtgg ttgcatttat ctttagcagc ttctaccatc ggaatgatct tttcggccag
    10681 ttccttagtc ttttctgcat ccagcatatt gttgatccat tcagcaaata cttctttgta
    10741 ttcagccggg cagcaatcag aagcgatagc ttcgttcatt actttcacca gacgggcacg
    10801 catcttttcg ttagccagtt ccatacccag accaaattca cagaagtctt cgaacaagga
    10861 gttagcccat gcaggaccgt gacccttttc gttcatagtg tacggagtag aaggaactga
    10921 accggagtag atagaagaac atcctgtagc gttagcaacc atttcacggt caccgaacaa
    10981 ctgagaaatc agtttcacgt acggagtttc accacaaccg gagcaagcgc ctgagaactc
    11041 aaacaacgga gttgcgaact gagagttctt cacgttagcc ttgatgtcta ccaggtgttg
    11101 tttgctcttc acgttttcag cgcagtaagt ccagttatca gcttcggcca actggctttc
    11161 aaggtgtttc atggtcaatg ccttgccacc cttcttcgga ttacccggac agatgtcggc
    11221 acagttaccg caacccagac aatcgagaac gtctacctga atacggaatg tcataccatc
    11281 gaatgcttta cctacagctt tcagttgctc gaacttagca cccttctgct cttcagcatc
    11341 gagtacgaac ggacggatag aagcgtgagg acaaacgtaa gcacacttgt tacactgaat
    11401 acagttttca gcattccatt cgggaacgaa tgcagctaca ccacgttttt cgtatttgga
    11461 agtaccttga taccaagtac cgtcttcgat acccttgaat gcagataccg gcagcaagtc
    11521 accgtcctgt gcattgatcg gacgaactac ttcgttgatg aaagcaggat cattgttttc
    11581 tgcttttgca tcatccggca ggttagccca agcaggatcg acagtcagag tcttgtattc
    11641 accaccgcgg tctacagcag cgtagttctt gttaacaacg tcttcaccct tcttgccgta
    11701 agacttaacg atgaatttct tcatctgttc aacagcttga tctacaggga ttacgcctgt
    11761 gatacggaag aatgcagact gaaggattgt attggtacgg ttgcccaaac caatttccat
    11821 tgcaatctga gttgcgttga tatagtatac agagatgttg ttctgtgcaa agtatttctt
    11881 caccttgtta ggcaggttct tagccagttc ttcgccttcc cagatggtat tcagcaagaa
    11941 agaaccgttc ttacgcaaac cacgtgttac gtcgtacatg tgcaggtaag cctgaacgtg
    12001 acaagcaacg aagttcggag tatttaccaa gtaagtagaa cggatcggag tatcaccgaa
    12061 acgcaagtga gaacaagtga aaccacccga cttcttggag tcgtaagaga agtaagcctg
    12121 acagtgtttg tcggtgttgt caccgataat cttaacagag ttcttgttgg cacctacagt
    12181 accgtcagca cccagaccgt agaatttagc ttcgaacata ccttcaccgc ccagagcgat
    12241 ttcttctttc tgaggaagag aagtgaacgt aacgtcgtct acgataccga tagtgaagtg
    12301 gttcttcggc attggcatag ccaagttttc gaatacagag atgatctgtg ccggagttgt
    12361 atcttttgaa cccagaccgt agcgaccgcc aacgataaca ggagcatttt ctgcgccata
    12421 gaagcagtct ttaacgtcaa ggtaaagagg ttcgccgtta gcacccggtt cttttgtacg
    12481 gtcaagcact gcgatgctct ttgcagtctt gggtacagca gccaggaagt gtttagcaga
    12541 gaacggacga tacaagtgta cggcaaccat acctactttt tcgccgtttg ctaccaagtg
    12601 gtcgatagct tcgcgggcag cttcagttac agaacccatt gcgataatta cgcgttctgc
    12661 atcttctgca ccgtagtaat cgaacaaacc gtatttgcgg cctgtgatct tggaaatttc
    12721 gttcatgtat tcttctacga tagcaggaac tgcttcatag tagttattgc atgattcacg
    12781 atgttggaag aagtggtcgg ggttttcagc cataccacgg gcaaccggct tcatcggatt
    12841 cagtgcacgg gcacggaatt cagccaaagc ttcctggtcg atcagcggag cgaggtcgtc
    12901 gttttccaac atttcgatct tctggatttc gtgagaagta cggaaaccat cgaagaagtt
    12961 catgaacgga acgcgtgatt tgatagtagc cagatgagca acacctgcca aatccataac
    13021 ttcctgtaca gaaccttctg ccaacatagc gaagccggtt tgacgagctg acattacgtc
    13081 ctgatggtca ccgaagatac acaatgcgtg agaagccagt gtacgagcag aaacgtggaa
    13141 tacacaaggc aagaattcac cggcaatctt gtacatgtta gggatcatca aaagaagacc
    13201 ctgagaagca gtgtaagtag tagtcaatgc accagcctga agagaaccgt gaactgcacc
    13261 ggcagcacca ccttcagatt gcatttcctg taccaatact gtttcgccga agatgttctt
    13321 acgtcctgcg gcagcccatt cgtctacgta ctcagccata gtcgaagaag gagtgatggg
    13381 gtagatagct gctacttcag agaacatata cgagatatgt gctgcagctt ggttaccatc
    13441 acatgtgatg aatttcttct gtttagtcat aactaaatta aatatttaag taaataaatc
    13501 tttttagtat aagaatccga acatccaaag aggtatttgg ttgccgcggc ctatctcagc
    13561 cttttgcaac gcatacgtca cgtccgggtt attctttatt tttgtacctt ccgcacaaat
    13621 tttgaacggc atcacttcgt ctaccatgaa agagacgttt ttatctcctt tatgtacctt
    13681 atggtctttc cataaagtgt taacgaagaa cgtgtcgagt acatcctgtt cttccacttt
    13741 caccggataa atggagtaca tcaggttaga gttgtgcatc ataatctttg acggtttctt
    13801 tgggaattct tctcctttcg ggtaaaccag attaatcaga cgcgcgtctg ccagatactt
    13861 gatatagttc attaccgtag cgcgggatgt ctgtacgtca cttgccagtt ggctcacgtt
    13921 cggagctttc ggtccgtcca cagccaacaa atatagtaat ttttttatct ttgaaagata
    13981 tttcagctca atttgtttga tcagcaagat atccacttct accatcatgt tcattgtttt
    14041 cagcagattc tccgagaaat tacgtttttc aaggaagaaa gggtagaaac catgatgcag
    14101 gtaatcctga aaataatcca gcggtcgtac tttggaaagt actcctttgg ctatctgttc
    14161 atgtgtactg aggatttctt cgaggctgta tgcccggaat ttcattcctg tctgcaggtt
    14221 cagaaattca cggaaagaga atccgcgcag gttataactt ttcgcaatgt cacgcaattc
    14281 gaggttttcc tctttgagtc gcatgacgga agaaccggtg aagacaatct tcaggctggg
    14341 gaaacggtca tagcacattc gtagctcttt gctccattcg ggatgtttga acacctggtc
    14401 gatcagcagt acttttccgc cacgtttctg aaactcgttg gcgaagtcaa caaggctgtg
    14461 accggagaaa taaaagttgt tcatattgat gaacagacag gaacggtcgg tgccgaattt
    14521 ctctttggcg tactgcagga ggaaagtggt ttttcctacg ccacgtgtcc ctttgatacc
    14581 aatcagacgg tcactccagt cgatctcgtc cataagatcg cggcgaacgg gggcattggt
    14641 gtgctcaacg aggtaggcgt gtgtgcgata gaatgattcc atttcgtttc tttgtttttc
    14701 ggctggcaaa tatagtgctt tttttaggat ttgcaaagta gagatagcaa aaatgtgctt
    14761 taatttataa gtttctcttt attgtgtaag ttcctgatta tttcctgtat atatttgcag
    14821 aataatgtgt tgaatccatc tttgacatga cgaaaagacc tgtttatata ttcaatccgg
    14881 agcatgatat ggcgttggca agcggtgaga cgaactatat ggcgccggct tccgcccgac
    14941 agatggcgag tgacctggcg ttgcttccta tgtggtatgc cgaagcggga agtgcggtgc
    15001 ttgcaccgtc tgcttataat gcggacttcc tgaaaacaaa gagtgaactt ttgggcatgg
    15061 atgtggcctt gttgacggaa ccggaagtgg ctgacggtaa agaccggaag ttctctccgt
    15121 gggggtggga ccctgctttg cggaagcgtt tgatgacatt gggggcagat cagacggagc
    15181 tgccttctgc ggattatatg aatattctga gagagcattc gcatcgtctg caggcggtaa
    15241 agttgttgcc tgggttgcgg ttgaatgaat acttctgtgg agaatctttt tatttgagta
    15301 ctttggcgga gtgcagtgcg ttcgtcgaag ggcgggaagc gtgcttgtta aaagctccgc
    15361 tttccggaag cgggaaagga ttgaattggt gtaaaggcat atttactact tttatttccg
    15421 gttggtgtgc ccgtgtcgct gcttctcagg gtggggtggt aggcgaacct atatataata
    15481 aggtggaaga tttcgctatg gagttttatg ctgacgggag aggaagggtt gtttttgccg
    15541 gatattcggt cttccacacg ggtgggagtg ggatgtatgc agggaatgac ttgctgtctg
    15601 acgagaagat tctgcagaaa ctatcggctt atgtgccaca agaagaattt atcaggctgc
    15661 ggactcgttt ggaagaagaa ttgtcagctt tgttcggtgg cttttatcat ggatacttgg
    15721 gagtggatat gatgatttgt cattttccgg atgaagcgcc tgtttaccgg attcatcctt
    15781 gtgtcgaaat taatctgcga atgaatatgg gggtggtggc atggctcttg acggatcgtt
    15841 atttggctgc ggatgcggaa ggagtttttc ggattgatta ttatccttta gccggtcagg
    15901 ctttggagga acatcggcag atgtcggctt cgttcccttt gtccgtagag aataatcggg
    15961 tgtgtgccgg atatttgccg ttagtaccgg tgacgcctca aagccggtat cgtgcgtttc
    16021 ttttgcttac tctcccccag tgaaaaagat agtgcttttg ctctcatgct ctaacagttc
    16081 gtctgtatcc ctttattcat cgatgtttta gctgttagag atccagtggt agcagagtga
    16141 gagcaaggac ttgctctcac tctgcatcgt cctgataaat accgttttta ctgtgttatt
    16201 ctttgattta caggatgtta atatctgata tctcaactgt taacgtttga tttctcagat
    16261 attaataatt gagaaatcaa gtattaagga ctgataattt atgtattatt gactgatata
    16321 tgatttaatg ttttcagaga gagcagtact attgaagtag ctgatgcgtt caatgtgatt
    16381 ggaacatgcg gttaagtcaa tcaaatcaac agtagtttca gatagtttcg agcgtttgga
    16441 actaaagttt caagcgtatg aaactctagt ttctcaccga tgaaactaca gtttcacacc
    16501 gatgaaactc tggtttcaag caatggaaac tctttgaaga tactgctaaa ttggaattgg
    16561 tgaacatcgg aaaagtcata ttgtggtaat actgtgtact tccctaataa tggttgactt
    16621 gtttatctct aatagctgct atgtgttgac tagaaatatt actaaccctg gcagctgttt
    16681 actttattat tcctgcctcc ggtttactta tttttttctt a
//
