LOCUS       c00191_gnlPro..         5880 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FFEKAEGC_191.
ACCESSION   c00191_gnlPro..
VERSION     c00191_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 00:03:54
            Original ID  :: gnl|Prokka|FFEKAEGC_191
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5880
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..873)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg191_1"
                     /sec_met_domain="IlvN (E-value: 1e-47, bitscore: 150.2,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 4.8e-30, bitscore: 93.2,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGTVENVVIRDEFPLEKAREVLKNETIAVIGYGVQGPGQ
                     ALNLRDNGFNVIVGQRQGKTYDKAVADGWVPGETLFGIEEACEKGTIIMCLLSDAAVMS
                     VWPTIKPYLTAGKALYFSHGFAITWSDRTGVVPPADIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAIYQDATGNAMDRTIALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMG
                     PFHDAIKPVV"
     protocluster    1..5880
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:5809]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1..5809
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..5880
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..5880
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(937..1680)
                     /locus_tag="ctg191_2"
                     /transl_table=11
                     /translation="MSEENKIGTYQFVAEPFHVDFNGRLTMGVLGNHLLNCAGFHASDR
                     GFGIATLNEDNYTWVLSRLAIELDEMPYQYEKFSVQTWVENVYRLFTDRNFAVIDKDGK
                     KIGYARSVWAMINLNTRKPADLLALHGGSIVDYICDEPCPIEKPSRIKVTSNQPVATLT
                     AKYSDIDINGHVNSIRYIEHILDLFPIELYQTKRIRRFEMAYVAESYFGDELSFFCDEA
                     NENEFHVEVKKNGSEVVCRSKVIFE"
     CDS             complement(1680..2243)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg191_3"
                     /sec_met_domain="ALS_ss_C (E-value: 2.7e-20, bitscore:
                     60.9, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDKTLYTIIVHSENIAGLLNQVTAVFTRRQINIESLNVSASSIK
                     GVHKYTITAWTDKDTIEKVVKQIEKKIDVIQAHYFTEDEIYFHEIALYKVSTPAFQETP
                     EASKVIRRYNARIVEVNPVFSIVEKNGMSEEITSLYEELRALKCVLQFVRSGRVAITTS
                     CFERVNEFLDGQEAKYKQSKKEQE"
     CDS             complement(2262..3959)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg191_4"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.2e-47, bitscore:
                     150.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKDLITGAEAMMRSLEHQGVTTIFGYPGGSIMPTFDALYDHQNT
                     LNHILVRHEQGAAHAAQGYARVSGKVGVCLVTSGPGATNTITGIADAMIDSTPIVVIAG
                     QVGTGFLGTDAFQEVDLVGITQPIAKWSYQIRRAEDVAWAIARAFYIASSGRPGPVVLD
                     FAKNAQVEKTKYEPTQQEFIRSYVPVPDTDEESVKAAAELINNAERPLVLVGQGVELGS
                     AQEELRIFIEKADMPAGCTLLGLSALPTDHPLNKGMLGMHGNLGPNINTNKCDVLIAVG
                     MRFDDRVTGNLATYAKQAKVIHFDIDPAEVNKNVKVDIAVLGDCKKTLAAVTGLLKKNR
                     HTEWVDSFKEYEAVEEEKVIRPELHPATDSLSMGEVVRAVSEATRHEAILVTDVGQNQM
                     ISARYFKYTRERSIVTSGGLGTMGFGLPAAIGATFGRPDRTVCVFMGDGGLQMNIQELG
                     TIMEQKAPVKIICLNNNYLGNVRQWQAMFFNRRYSFTPMLNPDYMKIASAYDIPSKRVF
                     SREELKVAIDEMLSTDGPFLLEACVVEEGNVLPMTPPGGSVNQMLLEC"
     CDS             complement(4007..5809)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg191_5"
                     /sec_met_domain="ILVD_EDD (E-value: 1.9e-218, bitscore:
                     714.6, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKQLRSSFSTQGRRMAGARALWAANGMKKNQMGKPIIAIVNSFT
                     QFVPGHVHLHEIGQLVKAEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMAAMRLNIPTVFVSGGPMEAGEWNGQHLDLID
                     AMIKSADDSVSDQEVANIEQNACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATH
                     ENRTKLFEDAAKLIVENAMKYYEEGDESVLPRSIATRQAFLNAMTLDIAMGGSTNTVLH
                     LLAVAHEAGVDFKMDDIDMLSRKTPCLCKVAPNTQKYHIQDVNRAGGIIAILAELAKGG
                     LIDTSVLRVDGMSLAEAIDQYSITSPNVTEKAMSKYSSAAGNRFNLVLGSQGAYYQELD
                     KDRANGCIRDLEHAYSKDGGLAVLKGNIAQDGCVVKTAGVDESIWKFTGPAKVFDSQEA
                     ACEGILGGRVVSGDVVVITHEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGG
                     TSGLSIGHVSPEAAAGGNIGKIVDGDIIEIDIPARTINVRLTDEELAARPMTPVTRDRY
                     VPKSLKAYASMVSSADKGAVRLID"
ORIGIN
        1 aactaccggt ttgatagcat cgtggaatgg gcccatccaa tcgagagcac cacgttgagc
       61 agtagtagag cagttagcat acatccagtc cataccgttc tttgcaaaca acggcatcaa
      121 tgactgagtc agctcttcta cagtttcgtt gaatgcttcg gaaggagtat gaccgttttc
      181 acgtaacact tcgtattgtg ccagcaacag accctggata gctcccatca atgaaccacg
      241 ttcgcctgtc aggtcggaag tagcttcgcg gatgaaagtt gtttcgaaca aataacctga
      301 accgataccg atacccaatg cgattgttct gtccatagcg ttgcctgttg catcctgata
      361 gatagcgtaa gaagagttca agccgcgacc ttcaaggaac atagtacgca aggatgtacc
      421 cgaaccttta ggagcaacca tgattacgtc gatatctgca ggaggaacta cacctgtgcg
      481 gtcactccat gtaatagcaa aaccatgaga gaaataaaga gcttttcctg cagtcaggta
      541 aggcttgata gtaggccata cagacattac tgctgcatca gacaacaggc acataatgat
      601 cgtacctttt tcgcaagctt cttcaatacc gaacaaagtt tcacccggaa cccatccgtc
      661 agcaaccgct ttgtcatatg tctttccctg gcgttgacca acgattacat tgaaaccgtt
      721 atcacgaagg ttcagagcct gtccgggacc ttgtacgcca taaccgatta cagcgattgt
      781 ttcatttttc aatacttcac gagctttttc caatggaaat tcatcacgga taactacatt
      841 ttctacagtt ccgccaaaat tcaactgtgc catttttttt gtttttttgt tttgatgact
      901 tgcgccatct gttattaatt gattttatac tctatattat tcaaatatca ctttggaacg
      961 gcatactacc tcgctgccgt ttttcttcac ctctacatga aactcgtttt cattcgcctc
     1021 atcacagaag aaagagagtt catctccgaa ataactttca gccacatacg ccatttcaaa
     1081 ccggcggata cgtttcgtct gatacagttc tatcggaaac aagtcaagta tgtgctcgat
     1141 ataacgaata ctgtttacgt gtccgttaat atcgatatca ctgtattttg ccgtcagcgt
     1201 cgcaacaggc tgattgcttg tcaccttgat acgcgaaggc ttttctatcg ggcagggttc
     1261 atcgcatata taatcgacga tgcttcctcc atgcaatgcc aacagatcgg caggcttacg
     1321 ggtattcaga ttgatcatcg cccatacgga acgggcatag ccgatcttct ttccatcctt
     1381 gtcaatgacg gcaaagttac ggtcggtaaa cagacgatag acattctcta cccatgtctg
     1441 aaccgagaac ttctcgtatt ggtaaggcat ctcatccagc tcgatagcca ggcgggaaag
     1501 cacccatgtg taattgtcct cgttcagcgt agcaatacca aatccacggt cgctggcatg
     1561 aaaacctgcg caattcaaca gatgatttcc cagcacgccc atggtcaggc ggccgttaaa
     1621 atctacgtga aacggctctg ccacaaactg ataagtccct attttatttt cttcactcat
     1681 tactcctgtt cctttttact ttgcttatac ttcgcttcct gtccgtccag gaactcattc
     1741 acacgttcga aacagctggt agtaatagcc acacggcccg aacggacaaa ttgcagcaca
     1801 catttcaaag cccgaagttc ttcgtaaagg gaagtaatct cttcactcat gccgttcttc
     1861 tcgacgatag agaataccgg attcacctct acaatgcggg cattatatct gcggatcact
     1921 ttagatgctt ccggagtctc ctgaaaagca ggagtagata ccttatataa ggctatctca
     1981 tggaaataaa tctcgtcttc cgtaaaatag tgcgcctgaa tcacatcaat cttcttttcg
     2041 atctgcttca ccaccttttc aatagtgtcc ttatcagtcc acgctgtgat cgtatattta
     2101 tgtactcctt taatggaaga agcagaaacg ttcaaactct cgatgtttat ttgccgacgg
     2161 gtaaatacag cggtcacctg atttagcaat ccggctatat tttcagaatg aactataatc
     2221 gtatataatg tcttatcact cataactttc taaattaagg attaacattc cagcaacatc
     2281 tgattgactg aaccgcccgg aggggtcatc gggaggacat tgccttcttc taccacacag
     2341 gcttcgagca ggaacggccc gtctgtcgag agcatttcgt cgatagccac tttcaattct
     2401 tcccgtgaaa agacacgttt ggaaggaata tcgtaggcgg aagcgatttt catgtaatcc
     2461 ggattcagca tcggagtaaa tgaataacgg cgattaaaga acatagcctg ccattggcgc
     2521 acgttgccga gataattgtt gttcaggcag ataatcttca ccggagcttt ctgttccatg
     2581 atcgtaccca gctcctgaat gttcatttgc agtccgccgt cacccataaa tacacataca
     2641 gtgcggtcgg gacggccgaa agtagctccg atagctgccg gaaggccaaa acccatcgtg
     2701 ccgagtccac ccgaagtaac gatactacgt tccctggtat atttaaagta gcgggcagag
     2761 atcatctgat tctgacctac atctgtcacc aatatggctt cgtgacgggt cgcttcgctt
     2821 accgcacgca ccacttcgcc catactcagt gaatccgttg caggatgaag ttcgggacga
     2881 atgacttttt cttcctctac cgcttcatat tccttgaaac tatcgaccca ctcggtgtgc
     2941 cggttctttt tcagcagtcc ggtcacagca gccagcgtct ttttgcagtc gcccaaaacg
     3001 gcaatgtcta cctttacatt cttatttact tccgccggat caatgtcaaa atggatcact
     3061 ttcgcttgtt tggcgtaagt agccagatta ccggtcacac ggtcgtcgaa acgcataccg
     3121 acagcaatca gtacatcaca tttgttagta ttgatattcg gtcccagatt tccgtgcata
     3181 cccagcattc ctttattcaa cggatggtcg gtaggcaatg cggaaagtcc gagcaaggta
     3241 caacctgcgg gcatatccgc cttttcgata aagatacgca gttcttcctg agcgcttccc
     3301 agttccactc cctgtcctac caagacaagc gggcgttcgg cgttattgat cagttcggcg
     3361 gcagccttta ctgattcttc gtctgtatcg ggaaccggaa catagctgcg gataaactcc
     3421 tgctgcgtcg gctcgtattt tgttttttca acctgcgcat tcttggcaaa gtcgagtacc
     3481 accggaccgg gacgaccact actggcaatg tagaaagcac gtgctatcgc ccaggctacg
     3541 tcttcggcac ggcgaatctg atagctccat ttagcgattg gctgagtgat acctacgaga
     3601 tcgacttcct gaaaagcgtc tgttccaaga aagcctgttc ccacctgtcc tgcaatgaca
     3661 acgataggcg tactgtctat catcgcatct gcaatacctg tgatcgtatt ggttgctccg
     3721 gggccgcttg tcaccaagca aacaccgact ttacccgata cacgggcgta gccttgtgcc
     3781 gcatgggcag ctccctgttc atggcgaacc aagatatggt tcaatgtatt ttgatggtcg
     3841 tacagggcat cgaacgtagg catgatggaa ccgccgggat aaccgaaaat ggtagtcact
     3901 ccctgatgtt ccagagagcg catcattgcc tctgcgcctg ttattaagtc cttactcata
     3961 gttctttaat ggataatgga tgattcataa tggataatga agtggatcag tctattaatc
     4021 tcactgctcc cttatcggca gagcttacca tgctggcgta tgctttcagg ctcttcggca
     4081 cgtaacggtc acgggtgacg ggagtcatcg ggcgggcagc cagttcttca tctgttagtc
     4141 gcacgttaat cgttcgggcg ggaatgtcga tttcgatgat atctccatct actatttttc
     4201 ctatattacc tccggcagcg gcttcgggag aaacgtgtcc gatactcaat ccggaagttc
     4261 caccactgaa acgtccgtcg gtaatcaagg cacattcttt gccgaggtga cgggatttga
     4321 tataagaagt cgggtaaagc atttcctgca taccgggacc gcccttcgga ccttcgtgcg
     4381 tgatgacgac aacgtcgccg ctgacgactc ggcctccgag gatgccttca caggctgctt
     4441 cttgtgagtc gaatactttg gcaggtccgg taaacttcca gatgctttcg tctacacccg
     4501 ccgtttttac tacgcaaccg tcctgagcga tatttccttt cagtaccgcc aggcctccgt
     4561 ccttgctata ggcgtgctcc agatcacgga tacatccgtt cgcgcgatct ttatctaatt
     4621 cctgataata agctccctga gaaccaagta cgagattgaa tctgtttcct gccgcacttg
     4681 aatatttgct cattgctttt tccgtaacgt tcgggctggt aattgaatat tgatcgatcg
     4741 cttccgccag cgacatgcca tccacacgga gaacggaagt atcaatcaga ccgccttttg
     4801 ccaactctgc caggatagca atgatgccac ccgcacggtt aacgtcctga atatgatatt
     4861 tttgagtatt cggagcgact ttacacaggc agggtgtctt gcgtgacagc atatcgatgt
     4921 cgtccatctt gaaatcgact cctgcctcat gtgccacggc caacaggtga agcaccgtat
     4981 tggtagaacc gcccatcgca atatccagcg tcatggcatt gaggaatgcc tgacgggtag
     5041 ctatgctgcg aggaagtaca ctttcgtcac cttcttcata atatttcatt gcattttcca
     5101 caatcagttt ggcagcatct tcaaacagtt tcgtacgatt ttcgtgcgta gccacgattg
     5161 tgccgtttcc cggaagagcc aagccgatag cttcattcag acagttcatc gagtttgccg
     5221 taaacattcc ggaacaacat ccgcaggtag gacaggcatt ctgttcgata ttcgctactt
     5281 cctgatcgct tacactgtcg tccgccgatt taatcatggc atcgatcaag tccagatgct
     5341 gaccgttcca ctctccggct tccatcggtc caccggatac aaatacggta gggatattca
     5401 ggcgcatggc agccatcagc atccctgggg taatcttatc gcagttgctg atacatacca
     5461 ttgcatccgc cttgtgcgca ttgaccatat attctacgct gtccgctatg atatcacggg
     5521 aaggaagcga gtaaagcatt ccgtcatgtc ccatagcgat accgtcatca atagcaatcg
     5581 tattaaattc cgcagcgaag catcccagct tctcaatttc cgccttcacc aactgcccga
     5641 tttcatgcag gtgcacgtgt cccggaacaa attgtgtaaa cgaattgacg atagcgataa
     5701 tgggttttcc catctgattt ttcttcatgc cgttggctgc ccataatgcg cgggctcccg
     5761 ccatccgacg gccttgtgta ctaaacgaac tgcgtaattg ctttttcatt tcaatctatc
     5821 ttttaattaa agagcctctc tcacatcagt gagaaaggct ctaaattcta tcttttatgg
//
