LOCUS       gnlProkkaAANGIOHF_518   4824 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AANGIOHF_518.
ACCESSION   gnlProkkaAANGIOHF_518
VERSION     gnlProkkaAANGIOHF_518
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 19:14:06
            Original ID  :: gnl|Prokka|AANGIOHF_518
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4824
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4824
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3886:4234]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3887..4234
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..4824
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..4824
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             3..449
                     /locus_tag="ctg518_1"
                     /transl_table=11
                     /translation="MRLPALFGTRESKSFESEREILYSVLFDMRQEVAELKKMVHNMMA
                     ERAGQVGQMGQVVATPVVTTTHQPSVPAIIHAVQQPSVCPKEDDDDIQDTEEYVEETLS
                     LDEVEKEMIRKALERHHGKRKSAAKDLNISERTLYRKIKEYELD"
     CDS             436..963
                     /locus_tag="ctg518_2"
                     /transl_table=11
                     /translation="MNWIKKIARPLILIVLPAVIIACSVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPNQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSSQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             968..1762
                     /locus_tag="ctg518_3"
                     /transl_table=11
                     /translation="MTSVNLQQWIQHPETLNRDTLYELRNQLARYPYFQSLRLLYLKNL
                     YILHDINFGAELRKAVLYIADRRKLFHLIEGERFAVESQKKGLPLSEVLKDEPTVDRTL
                     ALIDAFLSTAPEEVTSQTSFDYSMDYTAYLLEETPVADEPAEAMPKLKGHELIDNFIEK
                     SETDPVVYLKPLREEEKAKAASSAETNETGRTDETTETNTIEEEDDSCFTETLAKIYVK
                     QQRYSKALEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             1769..2164
                     /locus_tag="ctg518_4"
                     /transl_table=11
                     /translation="MYLLFIILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSVATAYVVPSSSAAKDVLLEQAQKEQQTNPYNMPTGTAAP
                     QTDATAPAESAPATEAPATETPAPVAE"
     CDS             2455..3843
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 90.8; E-value: 1.2e-27)"
                     /gene_kind="transport"
                     /locus_tag="ctg518_5"
                     /transl_table=11
                     /translation="MTEQLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AITTTFPEGAMLFGFKMQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGVFHTNIPAPILFCLVMLCVGTIAFFIYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMVIGAVMLIFVHTMFAL
                     PILNIWWFATVIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNSYCKGPVVDGAQTYDYTLPMAIFAMFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             3887..4234
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg518_6"
                     /sec_met_domain="PF05402 (E-value: 2.9e-18, bitscore: 55.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 1.2e-10, bitscore:
                     30.2, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATKEKINLLEVIPCRNEHIKAEQEGETIVLSFPRFKRSWMSRYL
                     LPKGMSKDIHVRLEEHGTAVWNLIDGQRTVREIIEKLADHFQHEAGYESRVSTYLSQLQ
                     KDGFIKWIIIH"
     CDS             complement(4224..4511)
                     /locus_tag="ctg518_7"
                     /transl_table=11
                     /translation="MGGEGHMLDMIRRLKDGKEASRLRRERRNDKLGRLRRNNDPYLLP
                     DTTPEEMERIIKDSEKKKEKDNSYFVWGTLIIMGVLIGCAVLLWAIFFNG"
     CDS             complement(4533..4823)
                     /locus_tag="ctg518_8"
                     /transl_table=11
                     /translation="MTPFYISLKDLKTVKIPQEDGKKKKEMEGIAYNVPGQAMVTLTDG
                     KKKLYEGEIPVTQFGIIEYLAPVLFNKNSTIKVYFDPVTGGLLKVDREESK"
ORIGIN
        1 cccaacgcct tccggcactg ttcggcacac gcgagagcaa gagctttgag agcgaacgcg
       61 aaatactata ttctgtcttg ttcgatatgc gtcaggaagt ggcggaactg aagaagatgg
      121 tgcacaacat gatggccgaa cgtgcgggac aagtcggaca gatggggcag gtagtggcta
      181 ctccggtagt gacaacgacg caccaacctt ccgtaccggc cattatccat gctgtgcagc
      241 aaccgtctgt ttgtcccaaa gaagacgatg acgatattca ggacacggaa gagtatgtgg
      301 aagaaaccct ttcgctcgat gaagtggaaa aagaaatgat acgtaaagcg cttgagaggc
      361 atcatggtaa gcggaaaagt gcggcgaagg atctgaatat ctccgagcgt accctttaca
      421 gaaaaataaa agaatatgaa ttggattaag aaaatagcac gaccgctgat actgattgtt
      481 ttaccggcag tcatcatcgc ctgtagtgtg tcctataagt ttaatggctc ctctatcaat
      541 tacgataagg tgaagaccat ttcgattgct gatttcccga ttaagtcgga gtatgtgtat
      601 gctccgctgg ctaccaagtt caatgaagac ctgaaagata tcttcatcag acagacccgt
      661 ctgcaactgc tgaaaccgaa ccagaatgcg gatctgcaga ttgacggtga aattacgggc
      721 tacaaccagt ataaccaggc agtgtctgcc gatggttact cttcggaaac gaagctgacc
      781 atcacggtca atgtacgctt tgtcaacaac acaaatcacg ccgaagactt cgaacaacaa
      841 ttctcagctt tccgtaccta tgattctagc cagctgctga cagccgtaca ggatggatta
      901 atagcggaaa tgagtaaaga gataaccgac caaatcttta atgcaactgt agcaaactgg
      961 taatttaatg acttctgtta acttgcaaca atggattcag catcccgaga cgctgaatag
     1021 ggatactttg tacgaactgc gcaaccagct cgcgaggtat ccgtattttc agtcgctccg
     1081 gttgttgtat ctcaagaacc tgtatattct ccacgacatt aatttcggtg cggaactgcg
     1141 gaaagccgtt ctgtatattg ccgaccgacg gaaactgttt catctgatcg aaggcgaacg
     1201 cttcgctgtc gaatcccaga agaaagggct gcctctctct gaagtattga aagatgagcc
     1261 taccgtcgac cggacactgg ctctgatcga tgctttcctt tcgacggctc ccgaagaagt
     1321 aaccagtcag acaagctttg attactccat ggactatacg gcataccttc tcgaagagac
     1381 acctgtcgcc gacgagccgg cagaggcaat gcccaagctg aaaggacacg agctgattga
     1441 caactttatc gaaaaaagcg agactgatcc agtcgtatac ctgaaacctt tgagggaaga
     1501 agagaaagca aaggcagctt cttccgctga aacaaacgaa acgggcagaa cagacgaaac
     1561 aactgaaacc aacaccatag aagaggaaga tgacagctgt ttcacagaaa ctttggccaa
     1621 aatctacgta aaacagcaac gatattcgaa agctcttgaa ataattaaaa aattaagctt
     1681 gaaatatcca aaaaaaaatg cttactttgc agaccaaatc agatttttgg agaaattgat
     1741 tattaacgct aattcaaaat aactaaaaat gtacttatta ttcattatct taatggtgat
     1801 tgcagccttg ctgatgtgct tcatcgtgct gattcagaat tcaaaaggag gcggacttgc
     1861 ttctggtttt tcttcatcaa acgctatcat gggcgtgcgc aagactacag attttctgga
     1921 aaaagcaact tggggtctgg ctatcttcat ggttgtgatg agcgttgcta ctgcttacgt
     1981 tgttccttct tcttctgcag ctaaagatgt attgttggaa caagcacaga aagaacaaca
     2041 aaccaacccg tataatatgc ctaccggtac tgctgctcct cagacagatg ctactgctcc
     2101 tgcagagtct gcaccagcaa cggaagctcc ggctactgaa actcctgctc ctgtagcaga
     2161 ataattcagt gacaggatat tcggtttaaa cttattgagt gaacgggctt tttgacccgt
     2221 tctcttcatt ataggcgcga attacgcgaa ttacaagaga ttctaataga atcgtgtaat
     2281 acgtgtagtt cgcgtctgtc tttattattg ggcccggtct gctcttcttc atacaggaat
     2341 atccggtcag atgtcctttt tcttataaaa tgttctcctt ttttagtaaa acaaatgata
     2401 attagttaac tttgttgccc gttacgagat tattaactcc ttttaaatat tacaatgaca
     2461 gaacaattga aacaaaagct gaatgactcc gcagtgctgc gttggagtgt tctagcatta
     2521 gtcgctttta ccatgttgtg cggctacttc ctcacagacg ttatgtctcc tctgaaaccc
     2581 atgcttgaaa aagaacttct ctgggacagt ttagattacg gttttttcac cagtgcttat
     2641 ggctggttta atgtattcct gctgatgctc atctttggtg gtatcattct ggataagatg
     2701 ggagtacgct tcaccggaat gggtgcctgt ttattgatgg tgttcggttg tggattgaaa
     2761 tattatgcta ttactactac tttcccggaa ggtgcgatgc ttttcggatt caagatgcaa
     2821 gtcacattgg ctgcattggg ttatgctatt ttcggtgtag gagtcgaaat tgcgggtatc
     2881 accgtttcga agattatcgt gaagtggttt aaaggcaaag agatggctct cgctatggga
     2941 ctggaaatgg cgaccgcgcg tattggaaca actttggcca tggtgcttac cgttcctttg
     3001 gcagacttct tcgggtctac ggatgagagc ggcgtattcc ataccaatat tcccgctccg
     3061 attctgttct gtctcgtcat gttgtgcgta ggtaccatcg cattcttcat ctatactttc
     3121 tacgataaga aactggatgc ttcactggat gcggaagggc tggaaccgga agaacctttc
     3181 cgcatgaaag acattgtcta tatcattacc aacaaaggat tctggctgat cgcattactg
     3241 tgcgtattgt tctattcggc tgtattcccc ttcatcaagt atgcggccga tttgatggta
     3301 cagaagtaca atgttgatcc gaaacttgcg ggaacgattc ccggattgct gccgattggc
     3361 gcgatcatcc tgacaccatt gttcggttca ttgtatgacc gtatcggtaa gggagccacg
     3421 ctgatggtga tcggggcggt gatgctgatt tttgtacaca cgatgttcgc tcttcctatt
     3481 ctgaatatat ggtggtttgc aacggtgatc atgattattc tgggatttgc tttctcattg
     3541 gttccttcgg caatgtggcc ttcggttccg aagattattc cggagaaaca gttgggaacg
     3601 gcttatgcgt tgatcttttg ggtacagaac tggggattga tgggcgtgcc tttgctgatc
     3661 ggatgggtgt tgaactctta ttgcaaaggt ccggttgtgg atggtgcaca gacttatgat
     3721 tataccctgc cgatggctat ttttgctatg ttcggtgtac ttgccctgat tgttgccttg
     3781 atgctgaaag cagaaaacaa gaagaaaggc tacggactgg aagaggcaaa tattcagaaa
     3841 taatccagta tatattctat ctgaaaagat ataaaagaga aaagatatgg ctacgaaaga
     3901 gaaaataaac ctcctggagg tgatcccttg tcgtaacgaa catattaaag ctgaacagga
     3961 aggggagact attgtgctct ccttccctcg ttttaaacgt tcgtggatga gtcgttattt
     4021 attgccgaaa ggaatgtcca aagatattca tgtgcgtctg gaagaacacg gtacggccgt
     4081 atggaacctg atagacggcc agcggacggt tcgtgagatt atagaaaaac tcgcagacca
     4141 ctttcagcat gaagcaggct acgagtctcg tgtatctacc tatctttccc aattacagaa
     4201 agacggattt attaaatgga taattatcca ttaaaaaaga ttgcccacag gaggacagcg
     4261 catcctatca gtacgcccat aatgatgagc gttccccata cgaaatagct gttatctttt
     4321 tcttttttct tttccgaatc cttgatgatg cgttccatct cttccggagt cgtatccggc
     4381 agaagataag ggtcgttgtt tcttctaagt cgccctaact tgtcatttct ccgttcacgg
     4441 cgtaagcggg aggcttcttt gccgtctttc agccgacgta tcatgtcgag catatgtcct
     4501 tcgccaccca tcgttttgtt tttttagagg ttttatttgc tttcttctct atctactttc
     4561 agtagtccac cggtcaccgg atcaaagtaa actttgatgg tcgagttctt gttgaataat
     4621 accggagcaa ggtattctat gataccgaac tgagtaacag gtatttctcc ttcatacaat
     4681 ttctttttgc cgtccgtcag cgtcaccatt gcctgtcccg gtacgttata agcaatgcct
     4741 tccatctctt tcttcttttt tccgtcctct tgcggaatct tcaccgtttt caggtctttc
     4801 agactgatgt agaatggagt gcct
//
