LOCUS       gnlProkkaKFFILHBI_18    9401 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KFFILHBI_18.
ACCESSION   gnlProkkaKFFILHBI_18
VERSION     gnlProkkaKFFILHBI_18
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 14:53:30
            Original ID  :: gnl|Prokka|KFFILHBI_18
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9401
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9401
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1320:5585]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1321..5585
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..9401
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..9401
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             3..1307
                     /locus_tag="ctg18_1"
                     /transl_table=11
                     /translation="MVQRTTRMIRSFLSRSPLYVLALYASVLIFLVYTCAYAYRKPFTA
                     AIYEGEILWGFDVKILYVLSEIIGYALSKFIGVRILPSMKAGHRIYYIIGLLTFSEVAL
                     LGFALLPVPLKVCSIFLSGLPLGMIWGVIFSYIEGRRISEILNVGLSVALIVSSGLVKT
                     LGQFVMDNLHVSEYWMPFTTGLLVYPVMLLCSWLLNQIPAPNEQDIIQRTKRAPMDGKD
                     RRKFLRQFFWGICMLVVFYGALTVFRELRDSFAADIWKELHIEGAMIFTQTEVPIAVFV
                     LVLMFLIVFVRNNRLALNIIYCIAVTGGSLMVFSTLLYVYGFLSPIWWMILSGLGLYMG
                     YIPFTYLIERLIASLRVVSTAVFIIYLADSFGYLGTTGVFMVKNFVSADISWTVMLMRT
                     ALFSGFVSVLSIFAIYCYFKQQLNSLILIPSEIHD"
     CDS             1321..2019
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_2"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.1e-14, bitscore:
                     44.4, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAGLGTRFGHYTELVPKGFVEVGGKPMIIRSIETLLSCGIERII
                     LGTGYKKEAYEALQADFPQIETCFSPRYADTNSMYTLYNTRDVIGDDSFLLLESDLVFE
                     RKAILSLLDDEFPDVMLVSSLTKFQDQYYVEYDRNHILTSCSVDKNALEAKGELVGIHK
                     LSNTFYRRMCADYATILESQPKLGYEYELLRMSRSVSPVRVLRVEGLKWYEIDDEADLS
                     YAEEHIIRYC"
     CDS             2039..3340
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 214.1;
                     E-value: 3.9e-65)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_3"
                     /sec_met_domain="CTP_transf_like (E-value: 1.1e-12,
                     bitscore: 37.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 8.3e-123, bitscore:
                     398.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 4.1e-65, bitscore:
                     208.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKIYVGMTADIMHPGLIHIIHEATKYGDVIVGLLTDKAIAEHK
                     RLPYLTYDQRKEVVENIKGVFEVVPQEDWSYVPNLEKLKPDYIIHGDDWKTGPLREVRE
                     QVFEVMNAQGGKVIEIPYTRGINSSSLDKDIKAIGTTPDVRLKSLRRLIQAKPVVRILE
                     AHDGLCGLIIENLEVQKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAVIIEDKVGLKKNSLFGTDAIQTQDS
                     IEGFCDKIRAGKNAQVTGDFMIIARIESLIAGKPMSDALERAYAYVQAGADGIMIHSKD
                     KSGEDIREFCRTFRKEYAHVPIVVVPTTYDHVHESELHEWGANVVIYANHLLRAAYPAM
                     MNVARTILENERAEEVRPLCMPIKEILELIPGTK"
     CDS             3352..4488
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 70.6;
                     E-value: 1.9e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_4"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.4e-22, bitscore:
                     69.4, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.5e-21, bitscore:
                     64.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSVEKIYDTFLHHGVDFFTGVPDSLLKNICAYITDHAPRGKHII
                     AANEGSAVGIACGYYMASGNVPLVYMQNSGLGNTVNPLLSLADEKVYSLPLLLLVGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMKIPFIILDTDEDEALAQIHDAVVSAKSRSIPHAIV
                     IRKDTFGKYKLRQEALNDYPLSREEALMQVVDHLGDNDIVVSTTGKLSRELFEYRESKG
                     QGHARDFLTVGSMGHSSSIALGIALEKPDRRVYCLDGDGAFIMHMGAVSNIGDLSPKNY
                     RHVLFNNGAHESVGGQPTLGFRLDIASIAKGCGYAHVLTASDKEGLSCALEKLSGLSGP
                     VLLEIKVRIDSRDDLGRPTTTPVENKEHFMAFLKDTHS"
     CDS             4485..5585
                     /NRPS_PKS="Domain: Aminotran_5 (30-293). E-value: 6.2e-34.
                     Score: 109.3. Matches aSDomain:
                     nrpspksdomains_ctg18_5_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 80.5; E-value:
                     1.9e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_5"
                     /sec_met_domain="Aminotran_5 (E-value: 6.9e-32, bitscore:
                     99.9, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIERKILLNPGPATTTDTVKLAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGDLSKHTAVLFCGSGTINIDICLNSLLPADKKVLVVNNGAYSTRAVEVCEYY
                     GLPHIDLKFSVYELPDLSVIEKTLSDNPDIALVYTTHHETGTGILNPIREIGKIAHSHG
                     AVFVVDTTSSLGMIPFDIGKDNVDFCMASAQKGLQAMTGLSFIIGDESLIRASRDYPKR
                     SYYCNLYLQYDYFEKTGEMHFTPPVQTVYAARQALDEYFAVGEEAKFARHKRVFEAIHK
                     GLQELGLQYAIKREWQSGLVVSVLYPDDPLWDFDKVHDYCYERGFTIYPGKISTTNTFR
                     LCALGEIDVEDIERFFEVMREAVLKY"
     aSDomain        4575..5363
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg18_5_Aminotran_5.1"
                     /evalue="6.20E-34"
                     /label="ctg18_5_Aminotran_5.1"
                     /locus_tag="ctg18_5"
                     /protein_end="293"
                     /protein_start="30"
                     /score="109.3"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGDLSKHTAVLFCGSGTINIDICL
                     NSLLPADKKVLVVNNGAYSTRAVEVCEYYGLPHIDLKFSVYELPDLSVIEKTLSDNPDI
                     ALVYTTHHETGTGILNPIREIGKIAHSHGAVFVVDTTSSLGMIPFDIGKDNVDFCMASA
                     QKGLQAMTGLSFIIGDESLIRASRDYPKRSYYCNLYLQYDYFEKTGEMHFTPPVQTVYA
                     ARQALDEYFAVGEEAKFARHKRVFEAIHKGLQELGLQYAIK"
     CDS             5605..7098
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_6"
                     /sec_met_domain="Polysacc_synt (E-value: 3.6e-11, bitscore:
                     32.2, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDKKNVVKWNFVFYLLEFLYTILVGIILVPLYLKYIPKDLYGFW
                     LATGNILSILTLINPGFSDVIQQKVAYCYGLHDYKKIGLYTVSGICLTFVFSLIVLIIG
                     VVVNLLIGSIFTMQANYLYELKIAFGLMLVGTFLTINYYSFSSILYAFLSSKSIGLIVL
                     LGNSLGTLISIYLIIHGYGLIALGIASVVRGGVFLSCSVGYVIFKFRKKKIKIVFDLNN
                     VKEIFSFSIYNFLGKTGQTLLTNMNSFLTAKFVSPIDAANLRFTQTVPEFGKVLVLRFL
                     YSVAPIIPNLLAAKGLESIRIKLLNIVYFLISFIFLVCIGFYLLNEQFIYLWLGENNFS
                     GKIINFFIIILLFFSSINKVCFQFLFALGDIKKSNKILFYQSLLYLPIAVFTTKFCGII
                     GLLLSGILVELLALFIFFFPKMVDILNISKIDIRKKLFVELTKISFVTVITLLIGSCVK
                     FSNPSWLLFFVEIVFIVLTFFVLLFLCSKTFRNLLSICK"
     CDS             7102..8247
                     /locus_tag="ctg18_7"
                     /transl_table=11
                     /translation="MKILLVFIDMIRVDHLSLYNDNMEKTSLDLFFENLGGTILTNCYT
                     PAPDTPRSIACLQSGLLPYLNGCDSRVKWPRYFMKPNIETIFDIAVGLGYKVNLCATKS
                     DIETGLFKFKENENISIFTTIEDFTDTVHLSENTLSLIAIDDYHSAIDDYGGTSLGIKE
                     GQKVILYSLNNFLTPDIVNKYDYSFFFSDHGHALQSEIVMQKNKLELLSDGRTKLFMFY
                     HNINNKKIVKDSRLASILDLYASIVDLIGSGDFRQGFSFFRDSQRDILHIEDHADFRVS
                     PEQIVSQWRVISDEIDIRTNVFETLNKKGQIIDINVVKKYLDSFSPSFSYYMKQIEILK
                     MYEKMKQRKTHYFNGVKRANWWIRCYVRIINRLYILINRLK"
     CDS             8244..9113
                     /locus_tag="ctg18_8"
                     /transl_table=11
                     /translation="MIVSSLRGGLGNQMFIYAMVKAMALRNNVPFAFNLTTDFANDEVY
                     KRKLLLSYFALDLPENKKLTFDFSYGNYYRRLSRNLGCHILHPSYRYICEERPPHFESR
                     LISSKITNAFLEGYWQSEKYFLDYKQEIKEDFVIQKKLEYTSYLELEEIKLLDKNAIMI
                     GVRRYQESDVAPGGVLEDDYYKCAMDIMASKVTSPVFFCFSQDLEWVEKHLAGKYPVRL
                     ISKKEDDSGTIDDMFLMMHFRNYIISNSSFYWWGAWLSKYDDKLVIAPGNFINKDSVPE
                     SWFKLNVR"
     CDS             9121..9399
                     /locus_tag="ctg18_9"
                     /transl_table=11
                     /translation="MNVLVTGAAGFIGSHVCKRLLQRGDEVVGLDNINSYYDINLKYGR
                     LSSLGVPQSELSWYKFTRSNVYPRFSFVRMNLEDRQAMQMLFANGNFD"
ORIGIN
        1 tatccgtaca gcgaactaca cgaatgattc gttcctttct ttcccgttct cccctttacg
       61 ttttggctct ctatgccagc gttttgattt ttctggttta tacttgtgcc tatgcctacc
      121 gtaagccatt taccgcagcc atttatgaag gtgagattct ttggggattc gatgtcaaaa
      181 ttctgtatgt cctttctgag attatcggct acgccctttc caagttcatc ggtgttcgta
      241 ttttgccttc gatgaaagcg ggtcaccgca tctattatat aatagggctg cttacttttt
      301 ccgaagttgc tttgttgggt tttgcacttc ttccggttcc tttgaaggtg tgttctattt
      361 ttctgagcgg tcttcccctg ggtatgatct ggggtgtcat ttttagctat atcgaagggc
      421 gtcgtatcag tgaaatattg aatgtcgggc tgagcgttgc tttgatagtc tcttccggtt
      481 tggtgaaaac cttgggacaa ttcgtgatgg ataatttgca tgtgtcggaa tattggatgc
      541 cttttaccac aggtttgttg gtataccctg ttatgttgct ttgcagctgg cttctcaatc
      601 agattccggc tcccaatgag caagatatca tacagcgtac caaacgtgct ccgatggatg
      661 gtaaagacag gcgtaaattt ttgaggcaat tcttctgggg aatctgcatg ctggttgttt
      721 tttacggtgc cctgaccgtg ttccgtgagc ttcgtgactc tttcgctgcc gatatttgga
      781 aggagctcca tattgagggt gcaatgatct ttactcagac agaggttccc attgccgttt
      841 ttgtccttgt actgatgttc ctgattgtgt ttgtccgtaa taaccgtttg gctcttaata
      901 tcatttattg cattgccgtc acaggcggtt ccttaatggt tttttccaca ttgctttatg
      961 tgtacggttt tctttctcct atttggtgga tgattctttc cggtcttggt ctgtatatgg
     1021 ggtatattcc tttcacttac ctgatagaac gtctgattgc ttcccttagg gtggttagta
     1081 cggctgtttt tattatttat ttggccgatt ctttcggcta tctgggcact acgggtgtgt
     1141 ttatggtcaa gaacttcgtt tctgctgaca tttcctggac tgtcatgcta atgcgtactg
     1201 cccttttttc aggatttgtt tctgtcctgt cgatttttgc gatttactgt tatttcaagc
     1261 aacaattgaa ttcacttata ttaattccct ctgaaattca tgattaaaac agcaatgatc
     1321 atggctgccg gtcttggtac ccgcttcggg cattataccg agcttgtgcc caaaggtttt
     1381 gtggaggttg gtggaaaacc tatgattatc cgctctatcg aaacccttct ttcctgcggt
     1441 atcgaacgta tcatcctcgg tacgggttat aaaaaagagg cttatgaagc ccttcaggcg
     1501 gatttccccc agatagagac ctgtttcagt ccccgttatg ccgatactaa cagtatgtac
     1561 actctgtaca atacgcgtga cgtgataggc gatgacagtt tcctgctgct tgaatcggac
     1621 cttgtttttg aacgcaaggc catcctttcg ctgctggatg acgaattccc ggatgtgatg
     1681 cttgtctctt ctctgaccaa gttccaggat cagtattatg tggaatatga ccgcaatcac
     1741 atccttactt cctgttcggt agacaagaac gcccttgagg caaaaggcga gctggtcggt
     1801 atccataaac tttccaatac tttctaccgc cggatgtgcg ccgattatgc gaccatcctg
     1861 gagtcccagc ctaaactggg ttacgaatac gaactgctcc gcatgtcccg ttccgtttcc
     1921 cctgtccgtg tgctcagggt ggagggtctt aaatggtatg aaatcgatga tgaagccgac
     1981 ctttcgtatg ccgaggagca catcatccgc tattgttaaa aacaaatctt ttccatatat
     2041 gaacaagaaa atttatgtcg gtatgaccgc ggatatcatg catccggggc tgatccatat
     2101 tattcatgaa gctactaaat acggtgatgt catcgtcggt ctgctgacgg acaaggccat
     2161 cgccgaacac aaacgcctcc cttaccttac ctatgatcag cgtaaggagg ttgttgagaa
     2221 tatcaagggg gtttttgagg ttgttcccca ggaggactgg agctatgttc cgaatctgga
     2281 aaaactcaag cctgactata tcatccacgg cgacgactgg aaaacgggcc cgttgcgcga
     2341 ggtgcgcgaa caggtttttg aggtgatgaa cgcccagggg ggcaaggtaa tcgagatccc
     2401 ttatacccgg ggcatcaact cctcctcgct cgacaaggat atcaaggcga tcgggactac
     2461 ccctgacgta cgtcttaagt ccctccgccg cctgatccag gccaagcctg tggtccgtat
     2521 cctggaggct cacgacggtc tttgcggtct gattattgag aatcttgaag tccagaaggg
     2581 ggataagcgc gaggtctttg acggcatgtg gtccagcagc ctgaccgact ccacgagtaa
     2641 gggtaaaccg gatattgaag cggtcgacct taccacccgt ttacaggacc tgaacaatat
     2701 ccttgaatgt accaccaagc ctattatttt tgatggagac acgggtggca agatcgaaca
     2761 ctttgtcttt actgtgcgca ctctggaacg tcatggcatt tctgcagtaa tcattgaaga
     2821 taaagtcggt ctgaagaaga attccctttt tggtactgac gctatccaga ctcaggatag
     2881 tatcgagggt ttctgcgata agatcagagc agggaagaat gcccaggtca ccggtgactt
     2941 tatgatcatt gcgcgtatcg aaagccttat tgccggcaaa cccatgagtg acgccctcga
     3001 acgtgcttat gcctatgtac aggcgggtgc ggacggcatc atgatccaca gcaaggataa
     3061 gtcgggtgag gatatccgtg agttctgccg gactttccgc aaagaatacg cccatgttcc
     3121 cattgtcgtt gttccgacga cttatgacca tgtgcacgaa tccgaacttc acgaatgggg
     3181 tgccaacgta gtcatttacg ccaaccacct tctccgtgcc gcttacccgg ccatgatgaa
     3241 cgtggccagg accatccttg aaaacgagcg cgccgaggag gtccgtccgc tttgtatgcc
     3301 tatcaaggaa attctggaat tgattccggg cactaaataa atcagacggt tatggtaagt
     3361 gtagaaaaga tatacgatac gttccttcat cacggtgttg acttctttac gggtgttccc
     3421 gattcccttt tgaagaatat ttgcgcctat atcacggatc atgctccgcg tggtaagcat
     3481 atcatcgccg ccaatgaagg ttccgcggtg ggcattgcct gcggttatta tatggcttct
     3541 ggcaacgttc ctttggttta tatgcagaac tccggtctgg gaaatacggt gaatcccctc
     3601 ttgtcccttg cggacgagaa agtgtacagc cttcctcttc ttttgctggt cggctggcgc
     3661 ggtgagcccg gcacaaaaga cgaaccccag cataagaagc agggcgaggt tacccttgat
     3721 cttctgaaag ccatgaaaat tccttttata attctggata cggatgaaga cgaggccctg
     3781 gcgcagatcc atgacgcggt tgtctcggcg aagagccggt cgattcccca tgcgattgtc
     3841 atccgtaaag atacgtttgg aaaatataaa ttgcgtcagg aagccttgaa tgactatcct
     3901 ctgtcccgcg aggaggcgct aatgcaggtt gtcgaccacc tcggggacaa tgacattgtg
     3961 gtttccacca cgggcaagct ctcccgtgag cttttcgagt accgtgaatc gaaagggcag
     4021 gggcacgcaa gggatttcct aactgtgggt tccatgggtc acagttcttc cattgccctg
     4081 gggattgccc ttgagaagcc tgaccgccgt gtctactgtc ttgacggtga cggtgccttt
     4141 atcatgcaca tgggtgctgt cagcaatatc ggcgatcttt ctcccaagaa ttacaggcac
     4201 gtccttttca acaacggtgc gcatgaatct gtcggcggtc aacccacgct cggtttccgt
     4261 ctggatatcg cctcgatagc gaaaggttgc ggttatgcgc atgtactgac tgcctccgac
     4321 aaggaagggc tttcgtgtgc gcttgagaag ctgtccggcc tgtccggccc ggttcttctt
     4381 gaaattaagg tccggatcga ttcacgtgat gatctgggtc gccctacgac tactccggta
     4441 gagaataaag agcattttat ggcattttta aaagatacgc attcatgaat atcgaaagaa
     4501 agatcctttt gaatccgggt cccgccacca cgacggatac ggtaaagctg gcgcaggttg
     4561 ttcccgatat ctgtccgcgt gagaaagagt ttgcgggtat gatgaaacag ttacgtgacg
     4621 acctggtccg cgttgcgcat ggagacctct ccaaacatac ggccgtcctg ttttgcggct
     4681 cgggtacgat caatatcgat atctgcctga actctcttct tcctgcggat aagaaagttc
     4741 tggttgtcaa taacggtgcc tatagcaccc gtgcggtgga agtctgcgaa tattacggtc
     4801 ttccccatat cgatttgaag ttttccgttt acgaacttcc cgacctgtcg gtaatcgaaa
     4861 agacgctttc cgacaatccg gacatcgctt tggtctatac cacgcaccat gaaacgggta
     4921 cgggtatctt gaaccccatc cgtgagatcg gaaaaatagc ccattcgcac ggtgccgttt
     4981 ttgttgtcga caccacttcc tccctgggta tgattccttt tgatatcggg aaggataatg
     5041 ttgacttttg tatggcttcg gctcagaaag gccttcaggc catgacgggt ctttccttta
     5101 tcataggtga tgaatccctg atacgtgctt caagggatta tccgaaacgc tcctactatt
     5161 gtaacctcta tttacaatac gattactttg agaagacggg tgagatgcat tttactcctc
     5221 ctgttcaaac cgtttacgct gcccgtcagg ctcttgatga atattttgca gtaggtgaag
     5281 aggctaaatt cgcccgtcac aagagggtct ttgaagccat ccataaaggt ttgcaagagc
     5341 ttggtcttca gtatgcgatc aaacgtgaat ggcagtcggg tcttgttgtt tctgtattgt
     5401 atcctgatga tcccctctgg gattttgata aggttcatga ttactgctat gaacgtggct
     5461 ttacgatcta cccgggtaag atttccacaa cgaatacatt ccggctttgt gcgttgggag
     5521 agattgatgt ggaggatatt gagaggttct ttgaggtgat gagggaggct gttttaaaat
     5581 actagagaaa ttgtcaattg ggatatgaaa gataaaaaaa atgtagtaaa atggaatttt
     5641 gtattttatc tcttggaatt tttgtataca attttagttg ggattatttt ggttccgttg
     5701 tatttgaaat atattccaaa ggatttatat ggtttctggc tagctactgg taatatattg
     5761 tctattttaa ctcttatcaa tcctgggttt tcagatgtga tacaacaaaa agttgcatat
     5821 tgttatggat tacatgatta taaaaaaata ggattatata ccgtttcagg tatttgtctt
     5881 acgtttgttt tttcattaat tgttttgata atcggagtag tagttaacct tttaataggt
     5941 agtatattta caatgcaagc taattattta tatgaattaa aaatagcttt tggcttaatg
     6001 cttgttggta catttttaac tattaattat tattcctttt cttctatatt atatgctttt
     6061 cttagtagta agtcaatcgg gctaattgta cttctaggca atagtttagg tactttaata
     6121 tctatttatc ttattatcca tggatatggt ctaatagctt tgggaattgc atcagttgtt
     6181 cgaggaggtg tttttttgtc atgtagtgtt ggctatgtaa tatttaaatt tcgaaaaaag
     6241 aaaataaaaa ttgtatttga tttaaataat gttaaggaga tcttttcttt ttctatatat
     6301 aattttttag gtaaaacagg acaaacattg ttgactaata tgaattcttt cttgactgct
     6361 aagtttgttt ctcctattga cgctgcaaat ttgagattta ctcaaactgt gccggaattt
     6421 ggtaaagttt tagttttaag atttttatat tctgttgctc ctattattcc taatttgtta
     6481 gcagctaagg ggttggagtc tattagaata aagcttttga atattgtgta ttttttgatt
     6541 tcctttattt tcttagtatg tattggtttt tatctattga atgaacaatt catatattta
     6601 tggcttggtg agaacaattt ttcagggaaa ataattaatt tttttatcat tattttattg
     6661 tttttttctt ctataaacaa ggtctgtttt cagtttcttt ttgcattagg agatataaag
     6721 aaaagcaata agattttatt ttaccaatct ttgttgtatt tacctattgc tgtttttaca
     6781 acgaaatttt gtggaataat tggtttattg ttatctggaa tattagtaga attattggca
     6841 ctattcattt tcttctttcc taaaatggtt gatattctta atatttcgaa aatagatatt
     6901 agaaagaaac tttttgtgga gttaaccaaa atatcttttg ttacggttat tacattatta
     6961 ataggttctt gtgtcaagtt ctctaatcct agttggctac ttttctttgt ggaaattgtt
     7021 tttattgtat taacattttt tgttttgttg tttttatgtt caaagacttt tcgtaattta
     7081 ttgtctattt gtaaataaaa gatgaagata ctactagttt ttatagatat gatacgtgtt
     7141 gatcatttat cattatataa tgataacatg gagaaaacat cgttggattt gttttttgaa
     7201 aatttaggag gtacaattct aactaactgt tatacacctg cacctgatac tccaagaagt
     7261 atagcttgtt tgcaaagtgg cctattaccc tatttgaatg gctgcgatag tcgtgtcaaa
     7321 tggccaagat attttatgaa acctaatata gaaactattt ttgatattgc agtagggtta
     7381 ggatataaag taaatttgtg tgcgactaaa tctgatattg aaacagggtt gtttaagttt
     7441 aaagaaaatg aaaatattag tatatttact actattgaag attttactga tactgttcat
     7501 ttgtcagaaa atacattgtc cttaattgcc attgatgatt atcattctgc cattgatgat
     7561 tatggaggaa cctcattggg aattaaagaa gggcagaaag tgatattata ttctttaaat
     7621 aattttctaa ctccagatat cgtaaataaa tacgactatt cgtttttctt ttcagaccat
     7681 gggcatgctt tgcagagtga aattgtcatg caaaaaaata aactagaact acttagtgat
     7741 ggaagaacta aactttttat gttctatcat aatattaata ataagaaaat agtaaaagat
     7801 tctaggcttg cttctatttt ggatctttat gcctctattg ttgatttgat tggtagtgga
     7861 gattttaggc aaggtttttc cttttttaga gacagtcaaa gagatatact tcatatagag
     7921 gaccatgctg attttagggt gtctccagag caaattgtga gtcaatggcg agtaatttca
     7981 gatgaaatag atattaggac taatgtattt gaaactttaa ataaaaaagg acaaataatc
     8041 gatataaatg tggtaaaaaa atatttagat agtttttccc cctcgttttc ttattatatg
     8101 aaacagatag agattctaaa aatgtatgag aaaatgaaac aacggaaaac gcattatttt
     8161 aatggggtaa agcgagctaa ttggtggatc cgctgttatg ttagaattat aaataggtta
     8221 tatatactaa taaatagatt gaaatgattg tatcatcttt gcgaggagga ttggggaatc
     8281 aaatgtttat ttacgctatg gtgaaggcca tggcattaag aaacaatgta ccattcgctt
     8341 ttaatttgac tactgatttt gcaaatgatg aagtttataa aaggaaactt ttattatcat
     8401 attttgcatt agacttgcct gaaaataaaa aattaacatt tgatttttca tatgggaatt
     8461 attatagaag gctaagtcgt aatttaggtt gtcatatact tcatccatca tatcgttata
     8521 tttgcgaaga gcgccctccc cactttgaat caaggttaat tagttctaag attacaaatg
     8581 cttttctgga aggatattgg cagtcagaaa aatattttct tgattataaa caagagataa
     8641 aagaggactt tgtaatacaa aaaaaattag aatacacatc gtatttggaa ttggaagaaa
     8701 taaaattgct agataagaat gccataatga ttggggttag acggtatcag gaaagtgatg
     8761 tagctcctgg tggagtgtta gaagatgatt actataaatg tgctatggat attatggcat
     8821 caaaagttac ttctcctgtt ttcttttgtt tttcacaaga tttagaatgg gttgaaaaac
     8881 atctagcggg aaaatatcct gttcgtttga taagtaaaaa ggaggatgat agtggtacta
     8941 tagatgatat gtttctaatg atgcattttc gtaattatat aatatcgaat agctcttttt
     9001 actggtgggg agcatggctt tcgaaatatg atgataagct ggtgattgct ccaggtaatt
     9061 ttataaataa ggattctgta ccagaatctt ggtttaaatt gaatgtaaga taaaatctta
     9121 atgaatgtat tagtaaccgg tgctgccgga tttataggtt cgcatgtttg taagcgtctt
     9181 ttgcaacgtg gggatgaagt tgtgggcttg gataatatta attcgtatta tgatattaat
     9241 ttaaagtatg gacgcctttc gagcttaggt gttcctcaat ctgaactgtc atggtataag
     9301 ttcacacgga gtaatgttta tcctcgattt agttttgtgc ggatgaacct cgaggatagg
     9361 caggctatgc aaatgctgtt tgctaatgga aattttgatg t
//
