LOCUS       c00066_gnlPro..        14098 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GJGBHIMH_66.
ACCESSION   c00066_gnlPro..
VERSION     c00066_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 01:22:37
            Original ID  :: gnl|Prokka|GJGBHIMH_66
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14098
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14098
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:4098]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2..4098
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..14098
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14098
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             2..1192
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg66_1"
                     /sec_met_domain="Fer4_10 (E-value: 3.6e-09, bitscore: 27.9,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 1.7e-16, bitscore: 51.1,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 5.5e-51, bitscore:
                     163.6, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 4.2e-13, bitscore: 40.4,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 5.9e-06, bitscore: 17.9,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="KGDMVKVGTKIAEPAGFVSAAIHSSVSGKVAKIDTVVDASGYAKP
                     AIFIDVEGDEWEETIDRSKTLVKECELSSEEIVKKIADAGIVGLGGACFPTQVKLCPPP
                     SFKAECVIINAVECEPYLTADHQLMLEHAEEVMVGVSILMKAVKVNKAFIGIENNKPDA
                     IELMTKVASSYAGIEVVPLKVKYPQGGEKQLIDAITKRQVASGALPISTGAVVQNVGTA
                     FAVYEAVQKNKPLFERVITVTGKSVAKPSNFLARIGTPMKQLIDACGGLPEDTGKVIGG
                     GPMMGKALVNIEVPTAKGSSGILIMNQKEAKRGEAQTCIRCAKCVSACPMGLEPYLLGA
                     LSENGDFETMEKERIMDCIECGSCQFTCPANRPLLDYCRLGKGKVGAMIRARQAKK"
     CDS             1199..2191
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg66_2"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 1.4e-120,
                     bitscore: 393.2, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLIVSLSPHVHGGDSVQKNMYGVLIALIPAFLVSLYFFGLGA
                     LIVTATSVAACLFFEWAIVKFLMKKPATTICDGSAVITGVLLAFNLPSNLPIWIIILGA
                     LFAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFPVQMTTWPVVGQLTSYMDATTGATPL
                     ALMKQAIHGDASALSQIPDALTLFIGQNGGCIGEVSALALLLGLVYMLWKKIITWHIPV
                     SIIVTVFVFAGIMHMVDPEKYVSPILQLLSGGLMLGAVFMATDYVTSPMSKKGMLIYGV
                     CIGLLTVVIRLFGAYPEGMSFAILIMNAFTPLINTYCKPKRFGEVAKKK"
     CDS             2218..2901
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg66_3"
                     /sec_met_domain="FMN_bind (E-value: 2.4e-23, bitscore:
                     73.8, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVLTGVTAVSVALLAYVNELTKGPIAEANAKTLNEALKKVLPE
                     YTNNPVAESDTVFSEKDGKKIVDFIIYPAKNGEKWVGSAVEAKSMGFGGELKVLVGFDA
                     EGKIYNYSLLAHAETPGLGSKADKWFGAYDPAKNEKPVSHEESAKSILGMNPGETPLAV
                     TKDMNGQVDAITASTITSRAFLNAVNAAYQAYKGGEVDTNSGASQKNEPAVAPEGEAAA
                     NDTNN"
     CDS             2919..3503
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg66_4"
                     /sec_met_domain="Rnf-Nqr (E-value: 3.8e-71, bitscore:
                     229.8, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNFKVMMNGIIKENPIFVLLLGMCPTLGTTSSAINGMGMGLATM
                     FVLICSNVVISSIKNLIPDMVRIPSFIVVIASFVTLLQMIMQAYVPDLYATLGLFIPLI
                     VVNCIVLGRAEAFAAKNNPLASMFDGIGMGFGFTIALTLLGAVREFLGTGKIFNLTILP
                     EEYGMLIFVLAPGAFIALGYLIAIINSLKKA"
     CDS             3526..4098
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg66_5"
                     /sec_met_domain="Rnf-Nqr (E-value: 6.5e-63, bitscore:
                     203.0, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFISAIFVNNIVLSQFLGICPFLGVSKKVETAMGMSAAVA
                     FVLTIATIVTFLIQKFVLDAFGLGYLQTITFILVIAGLVQMVEIILKKVSPSLYQALGV
                     FLPLITTNCCILGVAILVIQKDFDLLTGVVYAFSTALGFGLALVLFAGLREQMTLVKIP
                     KGMQGTPIALITAGLLAMAFMGFSGVV"
     CDS             4357..5391
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg66_6"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 1.2e-52, bitscore:
                     170.4, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKERILVTGGTGYIGSHTVVELQNSGYEVIIIDNLSNSSADVVDN
                     IEKVSGIRPAFEKLDCLDFAGLDAVFAKYKGIKAIIHFAASKAVGESVEKPLLYYRNNL
                     VSLINLLELMPKHGVEGIVFSSSCTVYGQPDELPVTEKAPIKKAESPYGNTKQINEEII
                     RDTVASGAPINAILLRYFNPIGAHPTALLGELPNGVPQNLIPYLTQTAMGIREKLSVFG
                     DDYDTPDGSCIRDFINVVDLAKAHVIAIRRILEQKQKEKVEVFNIGTGRGVSVLELING
                     FEKATGVKLNYQIVGRRAGDIEKVWANPDYANQELGWKAVETLEDTLRSAWNWQLKLRE
                     RGIQ"
     CDS             complement(5624..6448)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg66_7"
                     /sec_met_domain="GHMP_kinases_C (E-value: 3.4e-10,
                     bitscore: 31.4, seeds: 112, tool: rule-based-clusters)"
                     /sec_met_domain="GHMP_kinases_N (E-value: 4.2e-10,
                     bitscore: 31.0, seeds: 447, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITFPNAKINLGLSITEKRPDGYHNLETVFYPVALEDALEIRTSP
                     EADKKFSLHQYGMEISGNPEDNLVVKAYLLLDKEFHLCPIEIHLYKHIPSGAGLGGGSS
                     DAAFMLKLLNEHFQLNLSEDQLEIYAATLGADCAFFIRNAPTFAEGIGNIFSPIPLSLK
                     GYQILIIKPDVFVSTREAFANIHPHHPEYSIKEAIKRPVNEWKEILINDFEDSVFPQHP
                     VIGEIKAELYRQGAVYASMSGSGSSVYGLFEPEGTLPETDWGTNVFCFKGRL"
     CDS             6647..8200
                     /locus_tag="ctg66_8"
                     /transl_table=11
                     /translation="MAEQRRNSRNTKSTKVQPVNDYGRIQPQAPELEEAVLGALMIEKD
                     AYSLVSEILRPESFYEHRHQLIYAAITDLAVNQKPVDILTVKEQLSKRGELEEVGGPFY
                     ITQLSSKVASSAHIEYHARIIAQKSLARELITFTSNIQSKAFDETLDVDDLMQEAEGKL
                     FEISQQNMKKDYTQINPVIDEAYKLIQKAAARTDGLSGLESGFTKLDKMTSGWQNSDLI
                     IIAARPAMGKTAFVLSMAKNIAVDYRNPVALFSLEMSNVQLVNRLITNVCEIPSEKIKS
                     GQLASYEWQQLDYKLKDLLDAPLYVDDTPSLSVFELRTKARRLVREHGVRIIIIDYLQL
                     MNASGMAFGSRQEEVSTISRSLKGLAKELNIPIIALSQLNRGVESREGIDGKRPQLSDL
                     RESGAIEQDADMVCFIHRPEYYKIYQDDRGNDLRGMAEIVIAKHRNGAVGEVLLRFKGE
                     FTRFSNPEDDMVIPMPGEPAGAMLGSKLNAGAMPPPPPEPDFVPQGNNPFGATEGPLPF
                     "
     CDS             8522..10984
                     /locus_tag="ctg66_9"
                     /transl_table=11
                     /translation="MNISYNWLKEYVNFDLTPDETAAALTSIGLETGGVEEVQTIKGGL
                     EGLVIGEVLTCEEHPNSDHLHITTVNLGDGEPVQIVCGAPNVAAGQKVVVATLGTKLYD
                     GDECFTIKKSKIRGVESTGMICAEDEIGIGTDHAGIIVLPAEAVPGTLAKDYYNIKSDY
                     VLEVDITPNRADACSHYGVARDLYAYLIQNGKQATLQRPSVDGFKVENHDLDIEVVVEN
                     SEACPHYAGVTVKGVTVKESPEWLQNKLRLIGVRPINNVVDITNYIVHAFGQPLHCFDA
                     GKIKGNEVIVKTLPEGTPFVTLDEVERKLNERDLMICNKEEAMCIAGVFGGLDSGSTEA
                     TTDVFIESAYFHPTWVRKTARRHGLNTDASFRFERGIDPNGVIYCLKLAALMVKELAGG
                     TISSEIKDVCVAAPQDFMVELSYEKVNSLIGKVIPVETIKSIVTSLEMKIMNETVDGLT
                     LAVPPYRVDVQRDCDVIEDILRIYGYNNVEIPTTLNSSLTTKGEHDKSNKLQNLVAEQL
                     VGCGFNEILNNSLTRAAYYDGLENYPSNHLVMLLNPLSADLNCMRQTLLFGGLESIAHN
                     ANRKNADLKFFEFGNCYYFDADKKNPEKVLATYSEDYHLGLWVTGKKVANSWAHPDENS
                     SVYELKAYVENILKRLGLDLHNLVVGNLTDDIFATALSVHTKGGKRLASFGVVTKKLLK
                     AFDIDNEVYYADLNWKELMKAIRSVKISYKEISKFPAVKRDLALLLDKNVQFAEIEKIA
                     YDTEKKLLKEVELFDVYEGKNIEAGKKSYAVSFLLQDETQTLNDKMIDKIMSKLVKNLE
                     DKLNAKLR"
     CDS             11074..11763
                     /locus_tag="ctg66_10"
                     /transl_table=11
                     /translation="MAKTFTRLGKQIAIAVKAGGPEPENNPTLRSVIATCKRENMPKDN
                     IERAIKNAMGKDQSDYKSMTYEGYGPHGIAVFVDTLTDNTTRTVADVRSVFNKFGGNLG
                     TMGSLAFLFDHKCMFTFKIKDGMDMEELILDLIDYDVEDEYEQDDEEGTITIYGDPKSY
                     AAIQKHLEECGFEDVGGDFTYIPNDLKEVTPEQRETLDKMIERLEEFDDVQTVYTNMKP
                     EEGGNEE"
     CDS             11771..12016
                     /locus_tag="ctg66_11"
                     /transl_table=11
                     /translation="MEYVYRTQGTCSTNIELNVEDGVVKEVAFWGGCNGNLQGLSRLVK
                     GMKVEEVIKKLEGVRCSGRPTSCPDQLCHALHEMGY"
     CDS             12178..13434
                     /locus_tag="ctg66_12"
                     /transl_table=11
                     /translation="MMKNIFQDLKRKDHKRYLGGLDVFKYIGPGLLVTVGFIDPGNWAS
                     NFAAGSEFGYSLLWVVTLSTIMLIVLQHNVAHLGIVTGLCLSEAATKYTPKWVSRPILG
                     TAVLASISTSLAEILGGAIALEMLFDMPIMWGAVLTTLFVSIMLFTNSYKKIERSIIAF
                     VSVIGLSFIYELFLVEIDWPAATMGWVTPAFPKGSMLIIMSVLGAVVMPHNLFLHSEVI
                     QSHEYNKKDDASIKKVLKYELFDTLFSMIVGWAINSAMILLAAATFFKSGIQVEELQQA
                     KSLLEPLLGSNAAIVFALALLMAGISSTITSGMAAGSIFAGIFGESYHIKDSHSQVGVI
                     LSLGIALLLIFFIGDPFKGLLISQMILSIQLPFTVFLQVGLTSSRKVMGNYVNSRWSTF
                     VLYAIAVIVSALNIMLLFS"
ORIGIN
        1 aaaaggtgat atggtgaagg taggcacgaa gattgccgaa cctgccggct ttgtttcggc
       61 agcaattcac tcttcagtca gtggtaaagt ggcgaagatt gatacagtag tcgatgcgag
      121 cggttatgca aaacctgcta tctttattga tgtagaaggc gacgaatggg aagaaaccat
      181 tgaccgtagc aagacactgg tcaaagaatg tgagctttcg tccgaagaaa tcgtgaagaa
      241 gattgccgat gccggtatcg taggtttggg tggtgcttgt ttccctacac aggtgaaact
      301 ttgtccgcct ccttcgttca aggcagaatg tgtgattatc aatgcggtgg aatgtgaacc
      361 gtatctgact gccgaccatc agctgatgct ggaacacgcg gaagaagtca tggtaggtgt
      421 ctccattctg atgaaagccg tgaaggtaaa taaggcattt atcggaattg agaataacaa
      481 gccggatgct attgaactga tgacgaaagt tgcttccagt tatgcaggca tcgaagttgt
      541 tcctttgaaa gtgaaatatc ctcagggtgg tgagaaacag ttgattgatg cgattaccaa
      601 acgccaggtg gcaagtggtg cgctgcctat ctctactggg gcagttgtgc agaatgtggg
      661 tacggcattt gctgtttatg aagctgttca gaaaaataaa ccgttgtttg agcgtgtgat
      721 taccgtaact ggtaagtctg tggccaaacc ttccaacttc ctggctcgta tcggtacacc
      781 aatgaaacag ctgattgatg cttgtggcgg tctgccggag gatacgggaa aagtgatcgg
      841 tggcggtccg atgatgggta aggctctggt gaatatcgaa gttcctaccg caaaaggcag
      901 ttccggtatc ctgattatga atcagaagga agccaaacgt ggtgaagcac aaacctgtat
      961 ccgttgtgca aagtgtgtga gcgcttgtcc gatgggactg gagccgtact tgctcggagc
     1021 tttgtccgaa aacggagatt ttgaaacaat ggaaaaagaa agaatcatgg attgtatcga
     1081 gtgcggttcc tgtcagttca cttgtcctgc caaccgtccg ctgcttgatt actgccgctt
     1141 gggtaagggt aaagtagggg ctatgattcg tgcacgtcaa gctaaaaaat aacgaagtat
     1201 ggaaaataaa ttaatcgtat cactatcacc ccacgtgcat ggcggagaca gcgtacagaa
     1261 aaatatgtat ggtgtgctga tcgcactgat tccggctttt ctggtgtcgc tttatttctt
     1321 cggcctgggg gctctgattg tcacggctac ttcggtagca gcctgtttat tcttcgaatg
     1381 ggcgatcgtt aaattcttaa tgaagaaacc tgctacaacc atctgtgacg gttctgctgt
     1441 cattacaggt gtgttgctgg catttaatct accttccaat ctgcctatct ggattatcat
     1501 tctgggtgca ctgttcgcaa tcggtgtagg caagatgtct ttcggtggtc tgggctgcaa
     1561 cccattcaac ccggcattgg cgggacgtgt attcttgttg ctttctttcc cggtgcagat
     1621 gacaacatgg ccggtagtag gtcagctgac atcttatatg gacgctacca ccggtgctac
     1681 tccgctggca ttgatgaaac aggctattca cggcgatgca agtgctttga gccagatacc
     1741 tgatgcgctg actctgttta tcggacagaa cggcggatgt atcggtgaag taagtgcgct
     1801 ggcactgttg ctcggactgg tatacatgct ctggaaaaag atcatcacct ggcatattcc
     1861 ggtttctatc attgtgactg tatttgtatt tgcaggcatt atgcacatgg tggatcccga
     1921 aaagtatgtt tctccgatat tgcaactact ctccggaggt ctgatgctgg gagctgtctt
     1981 tatggcaacc gactatgtga cttctccgat gagcaagaaa gggatgctga tttacggtgt
     2041 ttgtatcggt ctgctgacgg tggttatccg tctgttcggt gcatatcccg aaggtatgtc
     2101 attcgccatc ctgattatga atgcgttcac tccgctgatt aacacctatt gtaaacctaa
     2161 acgctttggg gaggtagcga agaagaaatg aaaaagttac aatcatcttt aaagaatatg
     2221 ttgctggtac ttacgggcgt tacagctgtt tccgtagcgt tgctggctta tgtgaacgaa
     2281 ctgacgaaag gccctattgc cgaagcgaat gcaaagacgc tgaacgaggc cttgaaaaag
     2341 gtgcttcctg aatataccaa taatccggta gccgaaagcg atactgtttt cagcgagaaa
     2401 gacggaaaga aaatcgtgga tttcattatc tatccggcca agaatggcga aaagtgggta
     2461 ggttctgccg ttgaagccaa gtcaatggga tttggcggtg aactgaaagt gctggtgggc
     2521 tttgatgctg aaggcaagat ttataactac tctttattgg cgcacgctga aactccggga
     2581 ttgggttcga aagcggacaa atggtttgga gcttatgatc ctgcaaagaa cgaaaaaccg
     2641 gtatctcacg aagaaagtgc aaagtctatt ttgggcatga atccgggaga gactccattg
     2701 gctgtgacca aagacatgaa tggacaggta gatgctatca cggcttctac tatcacttca
     2761 cgtgctttcc tgaatgcggt gaatgctgct tatcaggcat ataaaggcgg tgaggtggat
     2821 acgaattccg gagcttccca gaaaaatgaa ccggctgttg cgccggaagg tgaagcagct
     2881 gctaatgaca ctaataacta agaaaggagg agacagttat gaataatttt aaagtaatga
     2941 tgaacgggat tatcaaagag aatcctattt ttgtgctcct gctcggtatg tgtcctacac
     3001 tgggtacgac atcatcggca atcaacggta tgggtatggg actggccact atgttcgtcc
     3061 tgatttgctc gaacgtggta atttcatcta tcaagaatct gattccggat atggtacgca
     3121 tcccttcatt tatcgtggtg atcgcgtcat tcgtgacact gttgcagatg ataatgcaag
     3181 catacgtgcc cgatctgtat gctactctcg ggcttttcat tccgctgatc gtagtaaact
     3241 gtatcgtatt gggacgtgcg gaagctttcg cagcgaagaa caatccgctg gcttctatgt
     3301 ttgatggtat cggtatggga tttggtttta ccattgccct gactctgttg ggtgccgtac
     3361 gtgaatttct cggaacaggt aagatattta atctgaccat tctgccggaa gaatacggaa
     3421 tgctgatctt tgttctggct ccgggtgcct ttatcgcttt aggttatctg attgccatta
     3481 ttaatagtct gaagaaagcc taactctatt aaataagaaa agaatatgga atatatattg
     3541 atatttatct cggcaatctt tgtaaacaac attgtgttgt cgcagttcct gggaatctgt
     3601 ccgttcctgg gtgtttccaa gaaggtggaa acagcgatgg gtatgagtgc ggcagttgct
     3661 ttcgtgctga ctatcgctac catcgtcaca ttcctgattc agaagtttgt gttggatgct
     3721 ttcggattgg ggtacttaca gacaatcact tttattctgg ttattgccgg actggtgcag
     3781 atggtagaaa ttattctgaa gaaagtttct ccttctttgt atcaggcact gggggtgttc
     3841 ctgccgttga ttacaacgaa ctgctgtatt ctcggtgtgg caatcctggt aatccagaaa
     3901 gactttgatc tgctgacagg tgttgtatac gcattctcta ctgctcttgg ctttggtctg
     3961 gcactggtat tgtttgccgg attgcgtgag cagatgaccc tggtgaagat tccgaaagga
     4021 atgcagggga ctccgattgc tttgattacc gcaggtttgc tggcaatggc attcatgggc
     4081 ttctctggcg tcgtgtaaaa gactaagttg ataattagat aaagaggctg gaaactctgt
     4141 cgtatggcaa catacaggca gtttgtttcc ggcctttttc tttatatctg ttcataccga
     4201 atatgttttt tatcatacca aaacgccctc aaatcgtccc gtaagtatct tcctgtgaat
     4261 aaaattgcga tagtttattg catttccatt ttatttccat acatttgtac ctcaaacaaa
     4321 ctgaaaaccg aaaaactaac catattttaa aattatatga aagaaagaat tttagtaacg
     4381 ggaggaacag gctatattgg gtctcatacc gttgtagaac tacaaaacag tggatacgaa
     4441 gtaatcatta tcgataattt atcaaattca agtgctgacg ttgttgacaa tatagagaaa
     4501 gtatccggta tccgcccagc ttttgagaaa ctggattgtc ttgattttgc tggccttgat
     4561 gccgtatttg ccaaatataa aggaattaaa gcgattattc atttcgcagc aagcaaagca
     4621 gtaggagagt cggtagagaa gccgttgctt tattatcgta acaacctggt ttctttaatc
     4681 aaccttctgg agttaatgcc taaacatgga gtagaaggca tagtgttctc ttcttcctgt
     4741 acagtatatg gtcaaccgga tgagttgcct gtaacggaaa aggctccgat caagaaagcg
     4801 gaatctcctt atggaaatac aaaacagatt aatgaagaaa ttatccgtga tacagtagct
     4861 tccggtgccc cgatcaatgc tattttgctg cgttatttca atccgattgg cgcacatcct
     4921 acagcattgc tgggtgaact tccgaacggt gttcctcaaa acctgattcc ttatctgact
     4981 cagacagcga tgggtatccg tgaaaaacta agtgtattcg gtgacgatta tgatactcct
     5041 gacggttcct gtatccgtga ctttatcaac gttgttgact tggctaaagc acacgtgatt
     5101 gcaatccgcc gtattttgga gcaaaaacag aaagaaaaag tagaagtatt caatatcggt
     5161 acaggacgcg gcgtttcagt attggaactg attaatggct ttgaaaaagc taccggcgtt
     5221 aaattgaatt atcagattgt aggccgtcgc gcaggtgata ttgaaaaggt atgggctaat
     5281 cccgattatg caaaccagga actgggttgg aaagcggtag aaacattaga agatacttta
     5341 cgctctgcat ggaattggca gctgaaactc cgtgaaagag gcattcagta aaaagatatt
     5401 tgttttaatt aacataaaag tttaaacaaa tcgttcatgc gatttgttta ttagatgcta
     5461 atcagcttga tctgtttgtg agtatgtgaa tatgagtaaa tggtacttat gcctctccgg
     5521 catagacagg tatgattgca tagtagtttt gtcgtgtttt attttgtgtt tgtgttgtga
     5581 cggtactacg acgggagtcg tggtaccgtt ttttgttact cttttacagc ctgcctttaa
     5641 aacagaatac gttagttccc caatcggttt caggtaaagt cccttccggc tcgaacaatc
     5701 catatacgga agaaccggaa ccgctcatag aggcataaac agccccttgc ctgtatagct
     5761 cggctttaat ttctccgatc accggatgct gggggaatac gctgtcttca aaatcattga
     5821 ttaatatctc tttccattca tttaccgggc gtttgatcgc ttctttgatc gagtattcgg
     5881 gatgatgagg gtgaatattg gcgaaagctt cccgcgttga tacgaataca tccggtttga
     5941 tgatcagaat ctgatatcct tttaaggata gtggaatggg ggagaatatg ttaccgattc
     6001 cttcggcaaa ggtcggggcg tttctgataa agaaagcgca gtctgctccc aaagttgcgg
     6061 catatatttc cagctgatct tcggataaat tcagctgaaa gtgttcgttg agtaatttca
     6121 gcatgaaagc cgcgtctgat gagcctcctc ccagtccggc accggaagga atgtgtttgt
     6181 acagatggat ctcgatagga cagaggtgaa actctttatc taatagcaga tatgctttca
     6241 ccactaaatt gtcttccgga ttaccagata tctccattcc gtactgatgc agggagaact
     6301 ttttgtccgc ttcggggctg gtccggattt ccagcgcatc ttcgagagcg acggggtaga
     6361 atacggtttc gaggttgtga tatccgtccg gacgcttctc ggtaatagag agtcccaggt
     6421 ttatttttgc gtttgggaaa gtgatcatat tcgttctgaa ttattatttt tgaattttaa
     6481 attatgggtt gcgaatttat gctattggtg acaaagttac taaaatcttc atttttcctt
     6541 atcttttctt cattattata ttctatcttt gtcatccctt tcggatttta ctatgtataa
     6601 aagccgggga tcataaattg taaatcataa aattgtatat aagcagatgg ctgaacaaag
     6661 aagaaattcc cgtaacacaa aatcaactaa agtacaaccg gtcaatgatt atggtcgtat
     6721 ccaacctcag gcaccggagc tggaagaggc ggtgttgggt gctttgatga ttgagaagga
     6781 tgcttattcg ctggtgagtg agattcttcg cccggagtca ttttatgagc atcgtcatca
     6841 gttgatttat gctgccatta ctgatcttgc cgttaatcag aagccggtgg acattctgac
     6901 ggtcaaagag cagttgagca aaagaggtga gttggaagag gtcggtggac cgttctatat
     6961 tactcagttg agcagtaagg ttgcttcttc cgcacatatc gaatatcacg cccgtattat
     7021 tgcacaaaaa tcgttggcgc gcgaattgat aacgtttacc agtaatattc aaagcaaggc
     7081 ttttgatgag acactggatg tggacgactt gatgcaggag gcggaaggca agttgtttga
     7141 gatttcccag cagaatatga agaaagacta tacgcagatt aatccggtaa ttgacgaagc
     7201 gtataagctg attcagaaag cggctgcacg aacggacggt ctgagtggtc ttgaaagtgg
     7261 atttacgaaa ctggacaaga tgacctccgg ttggcagaac tccgacctta ttataatcgc
     7321 tgcccgtcct gccatgggta agacagcttt cgtactttct atggctaaaa atattgctgt
     7381 tgattatcgg aatccggtag cgttgttctc tcttgaaatg agtaacgtcc agttggtcaa
     7441 ccgtcttatc accaatgttt gtgagattcc gagtgagaag atcaaaagtg gacaattggc
     7501 aagctatgag tggcaacagt tggactacaa actgaaagat ctgctggatg ctccgcttta
     7561 tgtggacgat actccgtctt tgtctgtgtt tgaactccgg accaaagcgc gtcgtctggt
     7621 gcgtgaacat ggggtgagaa ttattattat tgactacctt caattgatga atgcgagtgg
     7681 tatggcattc ggtagccgtc aggaagaggt tagtacgata tcccgttcgt tgaaaggatt
     7741 ggcgaaggag ttgaacattc ccattatagc cttgtcgcag ttgaatcgtg gtgtggagag
     7801 tcgtgaaggt attgacggta aacgccctca gttgagtgac cttcgtgaat ccggagccat
     7861 cgagcaggat gccgatatgg tgtgttttat tcaccgtccg gaatattata agatttatca
     7921 ggatgatcgt ggtaacgacc tgcgcggtat ggcggaaatt gtgatagcca agcatcgtaa
     7981 tggtgcggta ggtgaagtct tgctccgatt caaaggtgag tttacacgat tctctaatcc
     8041 ggaagatgat atggttatac cgatgccggg tgaacctgca ggtgccatgc tggggtctaa
     8101 actgaatgcc ggtgctatgc ctccgcctcc gccggaaccg gactttgttc cgcagggaaa
     8161 taatccgttc ggtgcaacgg aaggaccgtt acctttctaa aaaaacatct tttgggttga
     8221 atagaatgac cgcttagtca gatgaaaata accgctcgat ttactccaat cgagcggtcg
     8281 attatttttt atagagtata gccaagttgt attctgatag ggataggtgg caaaaatgac
     8341 aaagaatacc cctttgtttt ttgccacttt gtcaccaacc atgaatttat tggggaataa
     8401 tacagtcagg tccttgttag tttagcttct cttgacattt ttctctcaaa tcgttctatg
     8461 tcaaccgaaa aatcttatta actttgcgaa actttttgag aaacaataaa aatttaatta
     8521 tatgaatatc tcttataact ggctgaaaga gtatgtcaac tttgatttga cccccgatga
     8581 aacggctgct gcgctgacct caatcggctt ggaaacaggt ggtgtagaag aagtgcaaac
     8641 cattaagggt ggtttggaag gactcgtaat cggtgaagtg ctgacttgcg aagaacatcc
     8701 gaattccgac catttgcata tcactaccgt caatctggga gacggcgaac ctgtacagat
     8761 tgtatgcggt gctccgaatg tagctgccgg acagaaagta gtggttgcca ctttgggtac
     8821 caaactttat gacggtgatg aatgctttac tatcaagaag tcaaaaatcc gtggtgtaga
     8881 atctacaggg atgatttgtg cagaagacga aatcggtatt ggtactgatc atgcaggaat
     8941 catcgtgttg ccggctgaag ctgttccggg tactctcgcc aaagactatt ataatatcaa
     9001 gagtgactac gtactcgaag tagatattac tcctaaccgt gcagacgctt gctcacacta
     9061 tggtgtggct cgcgacttgt atgcttacct gattcagaat ggcaagcagg ctactttgca
     9121 acgtccatct gtagatggat ttaaggtgga aaatcatgat ttggatatcg aagtagtggt
     9181 tgaaaacagc gaagcctgtc ctcactatgc cggcgttacg gtgaaaggcg ttactgtgaa
     9241 ggaaagcccc gaatggttgc agaataaatt gcgcctgatc ggtgtacgtc ctattaataa
     9301 tgtagtggat attactaatt atatcgttca tgctttcggt cagccattgc attgtttcga
     9361 tgccggaaag ataaaaggca atgaagtaat tgtcaagaca ttgccggaag gcactccatt
     9421 cgtcacattg gatgaagtgg aacgcaagtt gaacgaacgc gatctgatga tctgcaacaa
     9481 agaagaagcg atgtgtattg ccggtgtatt cggcggactg gattccggtt ctacggaagc
     9541 tacgacagat gtatttatcg aaagcgctta tttccatcct acatgggtgc gtaagactgc
     9601 ccgtcgtcac ggtctgaata cggatgcttc tttccgtttc gaacgtggca tcgatccgaa
     9661 cggagtaatc tattgtctga aactggctgc tctgatggtg aaagaactgg ccggtggcac
     9721 tatctcatcc gaaattaagg atgtttgcgt tgcagctcca caagacttta tggtagaact
     9781 ttcttatgag aaagtaaatt cgctgattgg taaagtgatt cccgtggaaa cgatcaagag
     9841 cattgttacc agcctggaaa tgaaaatcat gaatgagaca gttgacggac tgacattagc
     9901 cgttcctcct tatcgtgtag acgtacagcg tgattgcgat gtgatcgaag atattctacg
     9961 tatctacgga tataataatg tagaaatccc gactacgctg aactccagtc tgacaaccaa
    10021 gggtgagcat gataaatcaa acaaattaca gaatctggtt gcagaacagt tggttggctg
    10081 tggcttcaat gaaatactga ataattctct gactcgtgcc gcttactacg acggtctgga
    10141 gaactatcca tccaaccatc tggtgatgct gctgaatcca ctgagtgccg atctgaactg
    10201 tatgcgtcag acattgctgt tcggtggact ggaaagcatc gctcacaatg caaaccgcaa
    10261 gaatgccgat ttgaaattct tcgaattcgg taattgctat tacttcgatg cggacaagaa
    10321 gaatccagaa aaagtactgg ctacctattc ggaagactat cacttgggtt tgtgggtgac
    10381 tggaaagaaa gtagccaact catgggcaca cccggatgaa aacagttcgg tatacgaatt
    10441 gaaggcttat gtagagaata tattgaagcg cctgggactg gatttgcaca acctggtagt
    10501 tggcaatctg actgacgata ttttcgctac cgcactttct gttcatacca agggggggaa
    10561 gcgtcttgcc tctttcggtg ttgtgacgaa gaaactgctg aaagcattcg atatagataa
    10621 tgaggtgtat tatgccgact tgaactggaa agaactgatg aaggctatcc gttcagtgaa
    10681 gatcagctac aaggaaattt ccaaattccc tgctgtgaag cgtgacttgg cattgttgct
    10741 cgacaagaac gtacagtttg ccgaaatcga aaaaatcgct tacgatacag aaaagaaact
    10801 gctgaaagaa gtggaactct tcgatgtata cgaaggtaag aacatcgaag caggtaagaa
    10861 atcgtatgcg gtcagcttcc tgcttcagga tgaaactcag acgctgaacg ataagatgat
    10921 cgataagatc atgtctaaac tggtgaagaa tctggaagat aagctgaatg caaaattgag
    10981 ataaatttaa aattcacaat tcaaaattaa tacaaaccaa tgggaagagc atttgaatat
    11041 agaaaagccg caaagctgaa aagatggggc cacatggcta aaacatttac aagactgggt
    11101 aaacagatcg ctattgccgt gaaggcgggt ggtccggaac cggaaaataa cccgacactg
    11161 cgttcggtca tcgctacttg taagcgtgag aatatgccga aggacaatat cgaacgtgcg
    11221 attaagaatg caatgggtaa ggaccagagc gactacaaga gcatgactta cgaaggatac
    11281 ggtcctcacg gaattgctgt ctttgtagat acgctgactg ataatacgac tcgtacggta
    11341 gccgatgtac gctctgtatt caataaattt ggtggtaacc tcggaacaat gggatcattg
    11401 gctttccttt tcgaccataa atgtatgttc actttcaaga taaaggacgg catggatatg
    11461 gaagaactga tccttgatct gattgattac gacgtagaag atgagtacga acaggatgac
    11521 gaagaaggaa caatcactat ctacggtgat cctaagagct atgccgctat tcagaaacat
    11581 cttgaagagt gtggcttcga ggatgtcggc ggtgatttta cttatatccc gaacgatctg
    11641 aaagaggtaa ctccggaaca acgcgaaact ttggataaga tgatagaacg tcttgaagaa
    11701 tttgatgacg tgcagactgt ttatacaaac atgaagccgg aagaaggcgg aaacgaggag
    11761 taagcggatt atggaatatg tttatagaac ccagggtact tgcagcacaa acatcgaact
    11821 gaatgtagaa gatggagttg tgaaggaagt tgccttttgg ggaggatgta acggaaatct
    11881 tcaaggactt tcacgtctgg taaagggaat gaaggtagaa gaggttatca agaaacttga
    11941 aggagtacgt tgcagtggca gaccgacgtc ctgtcccgat cagttgtgcc atgcactgca
    12001 tgaaatggga tattaacgga agtctccctt tataaaatat acactggcct ccggcaattc
    12061 attttgccgg aggtttttta ttgtgccgta cctttcccta tttgtcggta ttttgaacca
    12121 aaatcgacct tcggtcgtta tttataagta tatttgtgct gaataaacta ttatgcaatg
    12181 atgaagaata tttttcaaga cttaaaacgg aaagatcata aacgttatct gggcggactg
    12241 gatgttttta aatatattgg tcccggactt ttggtaactg tcggatttat tgatccgggc
    12301 aactgggcat caaattttgc cgcaggttcc gagttcggct attcacttct ttgggtggtc
    12361 accttatcca ctatcatgtt gattgtcctc cagcataatg ttgctcactt ggggattgtt
    12421 acggggcttt gcctttcgga agccgctacg aaatatactc ctaaatgggt atcccgtcct
    12481 attttgggta cggcggtatt ggcgtctatt tctacttcat tggctgagat tctgggagga
    12541 gccatcgcat tggagatgct gtttgatatg cctattatgt ggggggcggt gctgaccaca
    12601 ctttttgtct ccatcatgct ctttaccaac tcctataaaa agatagaacg ttccattatt
    12661 gcttttgtct cggtgatcgg tctttcattt atttatgaat tgtttctggt agaaatagac
    12721 tggccggctg cgacgatggg ttgggtgacg cctgctttcc cgaagggtag tatgctgatt
    12781 attatgagtg tgctgggagc ggttgtgatg cctcataatc tgtttctgca ttcggaagta
    12841 atacagagtc acgagtataa taagaaagac gatgcgtcta tcaagaaagt attgaaatac
    12901 gagttgttcg atacgctttt ctcgatgatc gttggctggg caattaacag tgctatgatt
    12961 ctgctggctg ctgctacttt ctttaaaagc ggcattcagg tggaagaatt gcaacaagcc
    13021 aaatcactgc ttgaaccttt gttgggaagt aatgcggcaa tcgtattcgc attggctctg
    13081 ttgatggcag gtatttcgtc cactataaca agcggaatgg cggcaggttc tatctttgca
    13141 ggtatctttg gagagtcata tcatattaaa gacagtcact cgcaggtagg agtaatcctt
    13201 tcgttgggaa ttgcgctgtt gctgattttc tttattggcg atccattcaa gggattactg
    13261 atttcgcaga tgatattgag tattcagttg cctttcacgg tattcctgca agtagggttg
    13321 acttcatccc gaaaggtaat ggggaattat gtcaatagcc gttggagtac ttttgtatta
    13381 tatgctattg cagtcattgt ttcggcattg aatataatgc tgctgttttc ataaaacgaa
    13441 cataaatcta taaactataa aatgatgaag attattactt ataatgtgaa cgggcttcgt
    13501 gctgccgttt ctaaaggttt gccggaatgg ctggtgcagg agaatccgga tattctttgt
    13561 ctgcaagaga caaaactaca gccggaccaa tatccggcag aagtatttga agctttgggt
    13621 tacaaggctt atctctattc tgcacaaaag aagggataca gcggtgtggc gatccttact
    13681 aagcaggaac ccgatcatgt ggaatatggt atggggatag aagcttatga caatgaaggg
    13741 cgttttatcc gtgcggattt tggcgacttg tccgtagtca gtgtttatca tccttcggga
    13801 acgagcggag acgaacggca ggcatttaaa atggtgtggc tggaagactt tcagaaatat
    13861 gtgacagagc tgcgcaagac tcgtccgaac cttatccttt gcggtgacta taatatctgt
    13921 catgagccga ttgatattca tgatcctgtc cggaatgcca cgaacagcgg cttcctgccc
    13981 gaagaacggg aatggatgac tcgtttcctt tctgcaggat ttattgattc tttccgtctg
    14041 ctctatccgg agaaacagga gtatacgtgg tggagctatc gttttaattc gcgtgcca
//
