LOCUS       c00003_gnlPro..        13327 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IMKNBGPO_3.
ACCESSION   c00003_gnlPro..
VERSION     c00003_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 19:38:52
            Original ID  :: gnl|Prokka|IMKNBGPO_3
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13327
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13327
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:3327]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2..3327
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..13327
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13327
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(2..988)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_1"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 1.3e-119,
                     bitscore: 391.8, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANKLIVSLSPHVHSGDSIQKNMYGVLIALIPALLVSFYMFGLGA
                     VVVTLTSVAACVFFEWAITKFILKRERSTICDGSAIITGVLLAFNLPSNLPLWIIIIGA
                     LVAIGVGKMTFGGLGCNPFNPALVGRIFLLISFPVQMTSWPLVQQWGSYTDAETGATPL
                     ALMKMAVKGDVNALGQLPDTLSLFLGNNPGSLGEVSALALLLGLGYMLWKKIISWHIPV
                     SILVTVFVFAGLMHLVDPVAYASPLAHLFTGGLMLGAIFMATDYVTSPMTHKGMIIYGV
                     AIGFLTVVIRLFGAYPEGMSFAIFIMNAFTPLINTYCKPKRFGEVVKK"
     CDS             complement(1003..2340)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_2"
                     /sec_met_domain="Fer4_7 (E-value: 1.3e-08, bitscore: 28.3,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 2.1e-16, bitscore: 52.5,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 1.3e-52, bitscore:
                     170.7, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 1e-30, bitscore: 98.7,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00012, bitscore: 15.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKTFRIGGVHPAENKLSAGKAIETLALPKQAVFPLSQHIGAPATA
                     IVKKGDVVKVGTKIAEAGGFVSAAIFSSVSGKVNKVDAVIDASGYRKPAIFIDVDGDEW
                     EESIDRSSTLVKECALTPEEIVAKVKNAGVVGMGGACFPTHVKLSPPPGCKAECVIINA
                     VECEPYLTADHRLMLEKADEVLVGVSILMKAAKVTKGYIGIENNKPDAIKLMTEKAAQY
                     PGIEVVPLQVKYPQGGEKQLIDAVIGRQVPAPPAIPINVGAVVQNVGTAFAVYEAVQKN
                     KPLFERIVTVTGKSVRNPSNFLTRMGTPMSQLIDAAGGLPEDTGKVIGGGPMMGKALVN
                     TEVPICKGSSGVLIMNDKEAARAEAQPCIRCAKCVNVCPMGLEPFLLATLSAHKDWERV
                     EKEDVMSCIECGSCQFTCPSHRYLLDYIRLGKGTVGGIIRARNAKK"
     CDS             complement(2380..3327)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 40.3; E-value:
                     1.2e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_3"
                     /sec_met_domain="Fer4_7 (E-value: 2.4e-12, bitscore: 40.3,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 2e-09, bitscore: 30.0,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 4.8e-08, bitscore: 25.8,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 3.1e-08, bitscore: 26.5,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_17 (E-value: 3.9e-07, bitscore: 23.5,
                     seeds: 82, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 1.1e-09, bitscore: 30.8,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00011, bitscore: 15.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLILVAVISLGAIGLIAAVILYAASKKFAVYEDPRIAKVSEVLP
                     QANCGGCGYPGCSGFAGACVKAADAGSLEGKLCPVGGAPVMEKVAAILGLEAVAAEPKV
                     AVVRCNGSCENRPRTALYDGAKSCAIAHATSGGETGCTFGCLGCGDCVEVCQFDAIHMN
                     PETGLPEVDEEKCTACGACSKACPRKIIEIRPKGKNNRRVVVMCVNKDKGAVANKACKA
                     SCIGCGKCVKVCPFEAITLENNLAYIDPAKCKSCRKCESECPKGAIQAINFPPRKPKVE
                     VPAGEAAAKPAAKVEASKVETPEAVKAEAPKAEA"
     CDS             complement(3348..3809)
                     /locus_tag="ctg3_4"
                     /transl_table=11
                     /translation="LSQFCNVEFAKMTDIIKHRGIVENIEGSHVRVRIVQTSACSACSV
                     KGHCNASESKEKLIDVFDMKASSYRIGEEVMIYGTTSMGMQAVLLAFGIPFLVLLITLF
                     ISMRFTGGDELRSALVALSALLPYYLIIYVCRNKLSKKFSFTLEPIKNN"
     CDS             complement(3955..5151)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_5"
                     /sec_met_domain="PALP (E-value: 1.2e-86, bitscore: 283.6,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLQLDAIYKAAHVLKEVVRRTDLIYAPQINPESTVYLKPENLQFT
                     GSFKVRGAYYKISQLSDEEKARGVIACSAGNHAQGVALAATKCGIKSLICLPEGAPISK
                     VEATKHYGAEVCLVPGVYDDAYQKALQLRDEKGYTFVHPFDDENVIAGQGTIGLELLEE
                     MPDVEVVIVPIGGGGLISGVAYALKALKPSVKVYGVQALGAASMANSILHSRIERLHSV
                     STFADGIAVKEPGTNTFDLVNQYVDGIVTVTEDEIAAAILALIERQRIVAEGAGAVSVA
                     AAMFNKVPVKGKKTVCLVSGGNIDVTILSRVISRGMAKSGRTYAVTLDLIDKPGQLLGV
                     SKIIAEQGGNVISVHHERNSESADVTGCALRVVMETRNEEHIASIRQKLLDAGYVIMK"
     CDS             complement(5332..6252)
                     /locus_tag="ctg3_6"
                     /transl_table=11
                     /translation="MNKQVEANLSMVVSKALGGLNMNALKYLLPLWIAPVTGVTFRLVF
                     GAAAFWLIDIFCKPENSTIRQKWQLFMLGALGIYGYMFFYLLGISKTTPVSSSIFVSLE
                     PIWVFIIAVLFYKEKVTWMKVFGIGMGLGGAILCISTQPSDDLASNAPLGNLMCLVSSL
                     VYAVYLVLSNRLLKGVGNMTMLKYTFLGAAVMAVIVNTIYGFDAPILRMSLFSTPMLVL
                     LFVLVFPTTISYLLLPLGLKYLKTTLVAIYGYLILIVATVTSFILGQDRFSWTQLAAIV
                     LICASVYLVEVAESKSEKQIISKSR"
     CDS             complement(6284..7474)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 56.2; E-value: 9.1e-18)"
                     /gene_kind="transport"
                     /locus_tag="ctg3_7"
                     /sec_met_domain="MFS_1 (E-value: 1.7e-17, bitscore: 56.2,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVQTGQGTIPLITLIGIFSISALNALPGLAVSPILGDLNKIFPS
                     ATDLEIQMLSSLPSLLIIPFILLSGKLTEKVNNLLLLQIGLTIFGVSGILYLLSNKMWQ
                     LIAISAMLGIGSGLIVPLSTGLISRYFVGAYRTKQFGYSSAITNITLVLATTLTGYLAE
                     VNWHLPFLVYLFPFISIFLTHYLKKDLSSYHPSDDIPSDTAKEMGKRGMNVKALIKLMA
                     FYGLATYLVIIISFNLPFLMEEYGLSSGRAGILISLFFLAIMAPGFVLNKIMQVLGRRI
                     YMVCLLMIACGMGIILLSRSEILIALGCVLNGLSYGIIQPLIYDKTSDVAVPHKVTLAL
                     AFVMAMNYVAILLCPFIVDAVQSLFHSDSQTFAFWLNLMVALMAMFVVMKQEKLSL"
     CDS             7862..9310
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyridoxal_deC"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_8"
                     /sec_met_domain="Pyridoxal_deC (E-value: 3.2e-67, bitscore:
                     219.7, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDCNCDLRDGDAKTAVFGSNEMLQPAPVDTIPMEPTTPQIAYQM
                     VKDETFAQTQPRLNLATFVTTYMDDYATKLMNEAININYIDETEYPRIAVMNAKCINIM
                     ANLWNSPEQAKWKSGALAIGSSEACMLGGVAAWLRWRDRRKAQGKPTDKPNFVISSGFQ
                     VVWEKFAQLWQIEMRQVPLTLDKTTLDPEEALKMCDENTICIVPIQGVTWTGLNDDVEA
                     LDKALDAYNAKTGYDIPIHVDAATGGFILPFLSPETKWDFRLKWVLSISTSGHKFGLVY
                     PGLGWVVWKDKKYLPDAMSFSVNYLGANITQVGLNFSRPAAQILGQYYQFIRLGFQGYK
                     AIQYNSMEITKYIHSEIAKMAPFVNYSDKVVNPLFIWYMKPEYAKNAKWTLYDLQAKLQ
                     QSGWMVPAYTLPENIQNYVVMRVVVRQGFSRDMADMLLNDIKNAISEFEKLEYPTPTRI
                     AQDKNIAVKGTVFTHNAHSNAAKK"
     CDS             9376..10338
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glutaminase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_9"
                     /sec_met_domain="Glutaminase (E-value: 8.4e-97, bitscore:
                     316.6, seeds: 316, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERTITIQQIKDAAQEAYNLYKDNTDGKNADYIPYLANIDPKLFG
                     ISICLMNGEIIQLGDSQYRFGIESVSKVLTAILVLRQYGAPKVLEMIGADATGLPFNSI
                     MAILLENDHPSTPLVNAGAISADSMVQPLGNSDGKWKAIVDNMTELCGSAPQLIDELYK
                     SESATNFNNRSIAWLLKNYNRIYDDPDMSLDLYTRQCSMGITAEQLSICGATIANEGLN
                     PNTNKQVFDKALAPKITSMIATVGFYQHTGDWLYTSGIPAKTGVGGGVMGVMPGVMGIS
                     AFAPPLDDAGNSVKAQLAIKYIMNKLGMNVFNGHRIHVQ"
     CDS             10512..10634
                     /locus_tag="ctg3_10"
                     /transl_table=11
                     /translation="MDELMQRNHLWSPSGDIERKLLKQPKAPDDVSYVIELTIK"
     CDS             10639..11502
                     /locus_tag="ctg3_11"
                     /transl_table=11
                     /translation="MSNKSKIEICANSVESAVKAQQAGAYRVELCAGIPEGGTTPSFGE
                     IRMARQLLNQTKLHVIIRPRGGDFLYSPIEQEIMLHDIKVARQLGADGVVFGCLTAEGN
                     VDVPLMQKLMNAVGEMSVTFHRAFDMCSNPKEALEQIIGLGIDRVLTSGQEATAEKGIP
                     LLKELVELADGRIIIMPGCGVNAGNIRKIAEETGTSEFHFSGRSSVDSGMIYRNSKVSM
                     GGTVKIEEYLKDVTDPNKVKAALSELALKDENDKALEKKNKSLNPKKSKKEDDWDDDDD
                     DLDDDK"
ORIGIN
        1 atttcttcac tacctccccg aatcttttag gtttacaata agtattgatt aacggagtga
       61 atgcgttcat aatgaatata gcgaaagaca taccttcggg atatgcaccg aacaaacgga
      121 taaccacggt caggaaaccg atagccacac cgtatataat cataccttta tgagtcatag
      181 gcgaagtaac atagtcggtt gccatgaaaa tagcacccaa catcaaacca cctgtaaaca
      241 agtgagccaa cggagatgcg taagccaccg gatcaaccaa atgcatcaga ccggcaaata
      301 caaatacagt caccagaata gatacaggaa tatgccagga aataatcttt ttccatagca
      361 tatatcccag gccaagcaat aaagccaatg cactcacctc acctagcgaa cccgggttat
      421 tacccagaaa cagacttaat gtatcgggca actgacctaa agcatttaca tcacccttta
      481 cagccatttt catcaatgcc agcggagtag caccggtttc agcatcggta taacttcccc
      541 attgttgaac caacggccat gaagtcatct gcacaggaaa agaaatcagc aagaagatac
      601 gacctaccaa cgcaggatta aaaggattac aacccaatcc gccgaaagtc atcttgccca
      661 caccgattgc caccaacgca ccgatgataa taatccaaag cggcaagttg gaaggcagat
      721 tgaatgccag caacacaccg gttataatag ccgaaccatc acagatggta gagcgttctc
      781 tcttcaaaat aaacttggta atcgcccatt cgaagaatac acaagcggca accgaggtca
      841 aggtcaccac cacggcgccc agtccgaaca tataaaatga caccagcaac gcaggtatca
      901 acgcaatgag tacaccatac atattcttct gtatgctgtc accgctatga acgtgaggcg
      961 ataatgatac tattaattta ttagccatac tattttgtcg aattattttt tagcattacg
     1021 tgcacggata ataccgccta ctgtgccctt acccaaacgg atatagtcca gcaaataacg
     1081 atgagacgga catgtaaact gacacgaacc gcactcgatg cacgacatta catcttcttt
     1141 ctctactctc tcccaatcct tatgagctga aagtgttgcc aataagaaag gctccagtcc
     1201 catgggacac acgttaacac acttggcaca gcggatacag ggctgagctt ccgcacgggc
     1261 agcttcctta tcattcataa tcagcacacc cgaactacct ttacaaatag gaacttctgt
     1321 attaaccagt gctttaccca tcatcggacc accaccaatc acttttcccg tatcttcggg
     1381 caaaccgcca gccgcatcaa tcagctggct catcggagtc cccatacggg tgagaaaatt
     1441 agatggattt ctgacagact tacctgtaac ggttacaatg cgttcaaaca aaggtttgtt
     1501 tttctgaacg gcttcataaa cggcaaatgc agtacctaca ttctgaacta ccgcacccac
     1561 attgatagga atagcgggag gagcaggaac ctggcgaccg atcacagcat ctatcaattg
     1621 tttctcacca ccttgcggat atttcacttg caagggaacc acctctatac cgggatattg
     1681 agcagctttt tcagtcatca acttaatagc atccggttta ttattttcaa taccgatata
     1741 tcccttggtt acttttgcag ctttcatcag aatgcttacg cccaccagta cttcgtctgc
     1801 cttttccaac atcaaacgat ggtcggcagt gaggtaaggc tcacactcta cagcattgat
     1861 aattacacat tccgccttgc agcccggagg aggagaaagt ttcacatgag tagggaaaca
     1921 agcaccgccc atacctacta cacctgcatt tttcacttta gcaacgattt cttcgggtgt
     1981 gagagcacac tctttcacca atgtcgaact gcggtctatt gattcttccc attcgtcacc
     2041 atccacatcg ataaagatag ccggcttgcg gtaaccgctt gcatcgatta cggcgtctac
     2101 cttgttcact ttaccggata cagacgagaa gatggctgct gaaacaaagc cacccgcctc
     2161 agcaatcttc gtacctacct tcaccacatc gccttttttc acgatggcag tagcaggagc
     2221 accgatatgc tgtgacaaag gaaataccgc ttgcttagga agtgcaaggg tttcaatggc
     2281 tttgcctgct gacaatttat tttctgctgg atgtactcca ccaattctaa atgtcttcac
     2341 tgttatatct ttttaatttt tacttacttt gaattttgat tatgcttccg ctttcggagc
     2401 ctcagctttc accgcttccg gagtttccac ctttgaagcc tctacttttg cagcaggttt
     2461 tgcagcagcc tcaccagccg gcacttctac cttcggttta cgtggcggga aattaatagc
     2521 ttggatagcc cctttcgggc attccgattc acatttacgg caagatttac acttagccgg
     2581 atcaatgtat gccaaattat tctctaacgt aatggcttcg aacggacaca ctttcacaca
     2641 ctttccacaa ccaatacaac tagccttgca agccttgttg gcaacagctc ccttatcctt
     2701 gttcacacac atcaccacta cgcggcggtt gttctttcct ttcggacgaa tttcaatgat
     2761 cttacgcgga caagctttgc tacaagcccc acaagctgta catttttctt cgtccacttc
     2821 cggaaggccg gtttcaggat tcatgtgaat agcatcaaac tgacacactt ccacacaatc
     2881 accacaaccc agacaaccga atgtacaacc cgtctcacca cctgaagtgg catgagcgat
     2941 ggcacacgat ttagctccgt catacagagc agtacgaggg cgattttcac aactaccgtt
     3001 acatcttacc accgcaactt tcggttcggc agcaacggct tccaatccca aaatggcagc
     3061 tactttctcc attaccggag caccaccaac cggacataac ttaccctcca gcgaaccggc
     3121 atcggcagcc ttcacgcagg caccagcaaa accagagcaa ccgggataac cacatccacc
     3181 gcaattcgcc tgaggaagca cttcgctcac cttggcaatc cgcggatctt catacacagc
     3241 aaacttctta gaagcggcat acaagattac cgcggcaatc aagccaatcg ctcccaacga
     3301 aattactgca accagaatta aatccataaa ttttagttag ttatttatta attatttttt
     3361 attggttcaa gtgtaaatga aaacttcttg ctcaacttat tcctgcatac atatatgata
     3421 aggtaatacg ggagcaaggc tgacaaagca acaagcgccg accttaactc atcccccccc
     3481 gtaaaacgca tggaaataaa taaagtaatc agcaatacca agaaagggat accaaaagcc
     3541 agcaatacgg cttgcatccc catggaagtg gtaccataaa tcatcacctc ctcacctatg
     3601 cggtaagaag atgccttcat gtcaaaaaca tcaatcagtt tctctttact ttcagatgca
     3661 ttgcaatgcc ctttcacact acaagccgaa caggcagaag tttgtacgat tctcacccgc
     3721 acatgagaac cttcaatgtt ttccacaata ccacgatgtt tgattatatc ggtcattttt
     3781 gcaaactcta cattacaaaa ctgcgacaaa tgtacgattt taattggatt ctaagaagta
     3841 taaaatgata ttttcactat aaaaatcgat tttttgtgtg gagaaattaa aattagaaac
     3901 aagaaaggga ggaaaatttt aaattccccc ctttctactt gtaaagtata taatttattt
     3961 cattatcaca tagcctgcat ccaagagttt ttgacgaatg gatgctatat gttcctcgtt
     4021 tctggtttcc ataacgacac gaagggcaca tccggtgaca tctgcactct cactatttcg
     4081 ctcatgatgt acagaaatta catttcctcc ctgctctgcg ataattttgc tgactcccaa
     4141 cagctgcccc ggtttgtcta tcaagtccaa agttactgca taggtacgtc ccgactttgc
     4201 cataccgcga ctgatgacac ggctcaatat cgtcacatca atattacctc cagacaccag
     4261 gcaaacagtt ttcttaccct ttaccggtac cttattgaac atggctgcag caacggacac
     4321 agctcccgcc ccctctgcaa caatccgctg gcgttctatc aatgccagaa tagctgcggc
     4381 aatctcatcc tcggtcacag ttacaattcc gtccacatac tgattaacca agtcaaaagt
     4441 atttgttccc ggctctttca ccgcgattcc atcggcaaaa gtggaaacag agtgaagacg
     4501 ctcaatacgc gaatgaagaa tagaatttgc catactggcc gcacccaacg cctgtacacc
     4561 atataccttg acagacggtt tcaaagcctt caacgcataa gccactcccg aaatcagtcc
     4621 gcccccacca atggggacaa tgactacctc cacatccggc atttcctcca ataactccaa
     4681 accgatagta ccttgtccgg ctatcacatt ctcgtcatca aagggatgaa caaaagtata
     4741 tcccttttca tcacgtaatt gcagagcttt ctgataagca tcatcataga ctcccggaac
     4801 caaacaaact tccgccccat aatgcttcgt agcctcaact ttagatatag gtgctccctc
     4861 tggaagacaa atcaacgact tgatgccaca cttagtggca gccaatgcca ccccttgcgc
     4921 atgattaccg gcagaacagg ctatcacacc tctcgccttt tcttcatcag acaattggga
     4981 aatcttgtaa taagcaccac gcactttaaa cgatcctgtg aattgcaggt tttcgggctt
     5041 cagataaact gtactctcag gatttatctg aggagcataa atcaaatcag tgcgacggac
     5101 aacctctttc aggacatgag ccgccttgta tattgcatct aattgtagca taggtataac
     5161 actcttgttt tttaattggg tgcaaagcta caaataaaat tgattcctta cactcgcttt
     5221 cgatgtaaag ttgcattctt ttttttcgct cattcatttg ccggtaagtt tctttacatt
     5281 acccaccgcg ataatttttt tcttagggtc ttatactttt ttcccggtgt cttatctgga
     5341 tttcgatata atctgttttt cacttttact ctcggccacc tctaccagat aaacactggc
     5401 acaaataaga acaatcgccg ccaactgcgt ccatgagaag cgatcctgcc ccaaaataaa
     5461 agaggtcacc gtggcaacaa tcaaaattaa atatccataa atagctacca atgtagtttt
     5521 cagatatttc aacccgaggg gaagtagtaa ataactaata gtggtaggga ataccaaaac
     5581 aaaaagcaag accaacatag gagtagagaa aagtgacatt ctcagtatag gagcatcaaa
     5641 gccgtaaatt gtattgacaa taacagccat gacagccgcc cctaaaaagg tatatttcaa
     5701 catcgtcata tttcccaccc cttttaacag acgattgctg agaacaagat agacggcata
     5761 aaccagcgaa ctgaccaaac acattaaatt acctaacgga gcattagagg caagatcgtc
     5821 actaggctgt gtagaaatgc aaagaatagc tcctcccaac cccattccaa taccaaacac
     5881 tttcatccaa gttacttttt ccttataaaa caatacagca ataatgaata cccatatagg
     5941 ctccaaactg acaaaaatgg aactggaaac cggagtggtc ttactgatac ccagcagata
     6001 aaaaaacata tatccgtaaa tacctaaagc ccctaacata aaaagctgcc atttctgacg
     6061 aatagtggag ttttcgggtt tgcaaaatat atcaataagc caaaaagcgg cggccccaaa
     6121 taccaatcgg aaagtaaccc ctgtcacagg agctatccac aaaggtaaaa gatatttcaa
     6181 tgcgttcata ttaaggcctc ccaacgcttt ggagacaacc atgctaaggt ttgcttcaac
     6241 ttgtttattc atacttcatg ctgttattac gtgggtattt ttcttataaa ctcaactttt
     6301 cttgcttcat caccacaaac atggccatca gcgccaccat caaattgagc cagaaagcaa
     6361 aagtctgcga gtcagaatga aacaagctct gtactgcatc tacaataaaa ggacaaagca
     6421 ggatagccac ataattcata gccatcacaa aggcaagtgc caatgtcacc ttatgaggta
     6481 cggccacatc agaggtctta tcataaatca acggctggat gataccgtat gaaagaccgt
     6541 tcaggacaca ccccaaagca atcaatatct cagaacggct gagcaaaata attcccatcc
     6601 cacaagctat catcaacaaa caaaccatat agatgcgacg ccccaacact tgcattatct
     6661 tgttcagcac aaagcccggt gccatgatag caaggaaaaa caaggaaatc aatattcctg
     6721 ccctgccact ggaaagcccg tactcttcca tcagaaaagg aaggttgaaa ctgataatga
     6781 ttaccagata agtagccaga ccgtaaaaag ccatcagctt gattaaggcc ttgacattca
     6841 ttcccctctt gcccatttct ttggcggtat cagacggaat atcatcagac ggatgataac
     6901 tggagaggtc tttcttcaga taatgagtaa gaaaaatgga tataaaagga aacagataaa
     6961 ccaaaaacgg caaatgccag ttcacttccg ccagatagcc agtcaatgta gtggccagta
     7021 ccaaggtgat attggttatg gcagaactgt aaccgaactg tttcgtacgg taagctccca
     7081 caaaataacg ggatatcaat ccggtggaaa gcggaacaat caacccggac cctatcccca
     7141 acatggcact gatggctatc agttgccaca tcttattgga gagcagataa aggataccac
     7201 tcaccccaaa gatggtcagg ccgatttgca gcagcaagag gttgttcact ttctctgtca
     7261 gcttacccga caacaagata aaaggaataa taagaagtga cggcaacgag gacagcatct
     7321 ggatttccaa gtctgtagca gacggaaaga ttttattcaa atcgcccaaa atgggagaaa
     7381 ccgccaatcc cggcaatgca tttaatgccg aaatggaaaa tatacctatt aaagtaatga
     7441 ggggaatggt cccctgccct gtctgtactt tcatacttgt agtaatttat tgtatgagat
     7501 acacaacaag gcaaaagacg tttggttcaa agcgacatat cgtttattcc tttactttcc
     7561 attccaaaat attatgccgg gtagtgtcaa agtttacgcc tatgttaatt tcctaaacgc
     7621 agtttatcaa attacatacc cctaaaatat cggatacggg catccaatga ttttatgtat
     7681 aaacaaaggt atctcttttt cgttcatagt acaatgattc ccatcgtttt tttgtattcc
     7741 ccctacttac attaaaaaac ataaaatcaa ggaacttttc accaacccct atgttgaggg
     7801 agaaaaacgc gggaaactcc cacgttcttc attgtattac taacctaaac tttaagtaaa
     7861 aatgaaagat tgtaattgtg atttgagaga cggtgacgcc aaaacagccg tgtttggttc
     7921 aaacgaaatg ctgcaacctg ctccggtaga caccattccc atggaaccta ccactccgca
     7981 gattgcttat caaatggtta aagacgaaac attcgcccaa acccagcctc gtcttaatct
     8041 ggctactttc gttaccacct atatggacga ttatgctacc aaattgatga acgaagctat
     8101 caacatcaac tatattgatg aaacagagta cccgcgtatc gccgtgatga atgccaaatg
     8161 tatcaacatc atggccaacc tatggaattc ccccgaacag gcaaaatgga aatcaggagc
     8221 gttggccatc ggctccagcg aggcttgtat gctgggtggt gtagctgcct ggttgcgctg
     8281 gagagacaga cgtaaagccc agggcaaacc gaccgacaaa cctaacttcg tcatttcaag
     8341 cggtttccag gttgtatggg agaaattcgc ccaactttgg cagattgaga tgcgccaagt
     8401 gcctcttact ctggacaaga ccaccctgga ccccgaagaa gccttaaaga tgtgtgacga
     8461 gaacaccatc tgtattgttc ctatccaagg tgtgacatgg acaggtctga acgatgacgt
     8521 agaagcattg gacaaagcac tggatgccta caacgccaaa accggctatg atattcctat
     8581 ccacgtagat gccgcaaccg gtggcttcat cctgccgttc ctcagccccg aaacgaaatg
     8641 ggacttccgt ttgaaatggg ttctttccat cagcacttcc ggccacaagt tcggactggt
     8701 ttatccggga ctgggatggg tagtatggaa agacaagaaa taccttccgg atgccatgtc
     8761 attcagtgtc aattatctgg gtgcgaacat cacacaggtt ggtttgaact tcagccgccc
     8821 cgccgcacag attctaggcc aatactatca gtttatccgt ctgggattcc aaggatacaa
     8881 agccatccaa tacaattcca tggaaatcac caagtacatt cacagcgaaa tagccaagat
     8941 ggctccgttc gtaaactaca gcgacaaagt ggtaaatcct ttgttcatct ggtacatgaa
     9001 acccgaatac gcaaagaacg ccaaatggac tctgtacgat ttgcaggcta aattacaaca
     9061 aagcggctgg atggttcctg cctacacctt gccggagaac attcaaaatt atgtggttat
     9121 gcgtgttgtg gtacgtcagg gattcagccg tgacatggcg gatatgttgt tgaacgacat
     9181 caagaatgcc atcagcgagt tcgagaaact ggaatatccc actcctaccc gcatcgccca
     9241 agacaagaat atcgctgtaa aaggtactgt gtttactcac aatgcccata gcaacgccgc
     9301 taaaaaataa gcataaataa caataatgca accatccgcc gttaaggtgg atggttactt
     9361 caatcaaatt aatttatgga aagaactata actatccagc aaataaagga tgctgcacaa
     9421 gaggcctaca atctgtataa agacaataca gacggtaaga acgccgacta cattccttat
     9481 ctggcaaata ttgatcccaa actgttcgga atcagtatct gtctgatgaa cggagaaatc
     9541 atccaactgg gtgactctca gtaccgtttc ggtatcgagt ccgtttccaa ggtgctgacc
     9601 gccatcctgg tactccgcca atacggcgcc cccaaggtgc tcgaaatgat tggcgccgac
     9661 gctaccggac tgccgttcaa ctccatcatg gctatcctgt tggaaaacga ccacccttcc
     9721 accccactgg taaacgccgg agccatctcg gcagacagca tggtacaacc cctaggcaac
     9781 agcgacggca agtggaaagc catcgtagac aatatgaccg aactatgcgg aagtgccccg
     9841 caactgattg acgaattgta caaatcggag tctgcaacaa atttcaacaa tcgttccatc
     9901 gcctggttat tgaaaaatta taaccgtatc tacgatgatc ctgatatgtc gcttgaccta
     9961 tacacccgtc agtgctctat gggcatcacc gcggaacaat tgtccatctg cggagccacc
    10021 atcgccaacg aaggattgaa cccgaataca aacaaacaag tgttcgacaa ggccctcgcc
    10081 ccgaaaatca cctccatgat agctaccgta ggtttctacc agcacacagg cgactggctt
    10141 tacacctcag gaatccctgc caagaccggc gtaggaggcg gtgtgatggg tgtgatgccg
    10201 ggtgtaatgg gtatttcggc cttcgcgcct cctttggacg atgccggcaa ctccgtaaaa
    10261 gcgcagcttg ccatcaaata tattatgaac aaactgggca tgaacgtatt caacgggcac
    10321 cgcatccacg tgcaataata tattctattc tgacagaaag ccgatatttc tctcaccccg
    10381 agagaagtac cggcttttta actaaaaaaa ttttccgcta aatatttctc acactcttac
    10441 attatgccta tctttgcaca gacaaattca tatattatga agaacaaagt catccgtaaa
    10501 gaactgggcc aatggatgaa ctcatgcaga gaaaccattt atggtcccct agcggagata
    10561 ttgaaagaaa attgctgaaa cagcccaaag cgcccgatga cgttagttat gtgattgaat
    10621 taactattaa ataactttat gagtaacaaa tcaaaaatcg agatttgcgc caactccgtg
    10681 gaaagtgctg tgaaggcaca acaagccggt gcttatcgtg tagaactatg tgcaggtatt
    10741 ccggaaggcg gaacaacccc gtcttttggc gaaatccgta tggcacgcca attattgaac
    10801 caaacaaaac tacatgtcat tatccgtccc cgtggcggag atttcctata ttctcccatc
    10861 gagcaagaaa tcatgttgca tgatattaaa gtggcacgtc agttgggtgc ggacggtgtg
    10921 gtgttcggat gtcttaccgc agaaggcaat gtcgatgtac ccttgatgca gaaactgatg
    10981 aatgcggtag gcgagatgag tgtcaccttc caccgcgctt ttgatatgtg cagcaatccc
    11041 aaagaagcct tggaacagat tatcggcctg ggtatcgacc gggtccttac ttccggacaa
    11101 gaagcgactg ccgaaaaggg tatccctctt ttaaaagaat tggtagaact ggccgacgga
    11161 cgaatcatca tcatgccggg atgcggtgtg aatgccggta atatccgtaa gattgccgaa
    11221 gaaaccggaa cttcggaatt tcatttctcc ggacggagca gcgtagacag cggcatgatt
    11281 tatcgtaact caaaagtatc tatgggaggt actgtaaaga tagaagagta tctgaaggat
    11341 gttactgacc ccaacaaagt aaaagccgcc ttgtccgaac tggcactgaa agacgaaaac
    11401 gacaaagcac tggaaaagaa aaacaaaagc ctcaacccca agaaatcaaa gaaagaggat
    11461 gactgggacg atgacgatga tgatttggat gatgacaagt aataagcaag cataaacgtt
    11521 attatcatat taaacgcgga tattcagggt ttcaagctga atatccgcgt tactttttgt
    11581 ttatactgaa ttctacaact tatgtatcac cttcatcagc tgctcaccca gcccgatggt
    11641 atatccttgt gacacgaata ccacccggtt aaaggtatca ccaatgataa acataggcaa
    11701 gatagtcttg ttagacaact tcatgccttc tgcaatctgc ttctggatgg aaccgtccac
    11761 atcaataccg taagtaatgg tagccggtaa tcctgggaat tcctgcggac ggaacttctt
    11821 gtactgctcc tcattgggga acaacagcac gattcctctg ccccattcat caaagtcctt
    11881 gcccaatgcc gcgatatcgc gcaatgcatg gttggtaggt tcttgtccgg cgcccagtac
    11941 ggctacaatg tagtaaccac gtcctgtagt ggcaagaatg gacttcagtt catcgctatc
    12001 catcggttta taagtagatt ctgaattgaa attaccgatc acctgaatat catccttact
    12061 ttcacgcatc accaagtcca ccgtagtcgt ttctcccggc ttgatggtaa agaaagtcag
    12121 ctgggacaat acgccgccgt tagccagacg agtaccggtc accatcacat aattgccggc
    12181 atccagtgcc gttccgttct tcaacagatt agcccaagta gcgccgccac ccatatcaat
    12241 atcgccttca tcataattca gcaatttcaa agttccggca ggagtcagtc tggaaataga
    12301 gaaatgagaa taatacttcg gatcagccaa agacttgatc ggcgtatatc tggcaataaa
    12361 cttgccggta agtgcactgg cctgttccat tgcttcgaaa ttcacatcaa tagcaccttc
    12421 atcgcctatc aactgcactt ttcccgtcac ttcgtctata cgtgcaggaa tacccatgct
    12481 gcgtgccatg gatacaaaga agatatcacg gctgtgcgca tcggctgtac gggccttcca
    12541 caccccttcc ggagtgattg gcgagccgcc caggttgcaa tccttgtcca cacggatatt
    12601 cccggcaacc catgcaacca gcttcatcgg atcggcaagg taagcctcac gatcctgttc
    12661 aggcactgct ttctcaaaga accctttata cggagtaatc atttcgttgc tcacgcgcgg
    12721 attacgcaca aatctgcgga aataatcagc attggcgcac aagtgtgaat tcatcatgtg
    12781 gtctatcaac acttcggagc ttacatcacg aaggtctttg gcagaaatct gctgaagcag
    12841 gtcaatgccg cccttctttg acttgtccga acggagacgg gccataaagt cacggatggt
    12901 ttcgtagttg ccacgtgatg ccaccagcaa tttggcaacg gcatcctcat ccagctggta
    12961 ttctttagcg aaattgcgag ccgattcatc cgtcatgaat gtagccacgt aggcattgcg
    13021 gatagagtcc tccaaagcca tgcggcgatt gttctccgca cgttgttcgg gagtcacttc
    13081 gggcatattg gcgccttcca tcggaggaat gatatccata tccagtgtat aagcctcgcc
    13141 ggccgttttg tccaatttca cggtcaaggc attgtcctgt ccgaaagaca gtttggaata
    13201 accgaatttt ccatctttgg aagcccatac cagcatatcc ccttttccgg cggtcaggaa
    13261 cgtcttaccg tccgcatccg tctgtttgga agctacggta taaaattcgg catagttata
    13321 caccttg
//
