LOCUS       c00465_gnlPro..        15195 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FFDNLIIP_465.
ACCESSION   c00465_gnlPro..
VERSION     c00465_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 23:31:19
            Original ID  :: gnl|Prokka|FFDNLIIP_465
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15195
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15195
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:8323]"
                     /cutoff="10000"
                     /detection_rule="(Oxidored_q4 and Oxidored_q6 and
                     Complex1_30kDa and Complex1_49kDa and NADHdh and
                     Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx,
                     Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding,
                     NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M,
                     Proton_antipo_N, SLBB]))"
                     /neighbourhood="10000"
                     /product="NADH_dehydrogenase_I"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2..8323
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Oxidored_q4 and Oxidored_q6 and
                     Complex1_30kDa and Complex1_49kDa and NADHdh and
                     Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx,
                     Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding,
                     NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M,
                     Proton_antipo_N, SLBB]))"
                     /neighbourhood="10000"
                     /product="NADH_dehydrogenase_I"
                     /protocluster_number="1"
     cand_cluster    1..15195
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Oxidored_q4 and Oxidored_q6 and
                     Complex1_30kDa and Complex1_49kDa and NADHdh and
                     Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx,
                     Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding,
                     NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M,
                     Proton_antipo_N, SLBB]))"
                     /kind="single"
                     /product="NADH_dehydrogenase_I"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15195
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NADH_dehydrogenase_I"
                     /region_number="1"
                     /rules="(Oxidored_q4 and Oxidored_q6 and Complex1_30kDa and
                     Complex1_49kDa and NADHdh and Oxidored_q3 and Oxidored_q2
                     and minimum(4, [Fe-2S_thioredx, Fer2_4, Fer4_7,
                     Molybdop_Fe4S4, Molydop_binding, NADH-G_4Fe-4S_3,
                     NADH_4Fe-4S, Proton_antipo_M, Proton_antipo_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(2..1054)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_M"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg465_1"
                     /sec_met_domain="Proton_antipo_M (E-value: 1.3e-51,
                     bitscore: 165.5, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFLSIFVLIPLLMLAGLWAARGIKAIRGVMVTGASALLIASVVL
                     TFMYLGERSAGNTAEMLFRADTLWYAPLHISYSVGVDGISVAMLLLSAVIVFTGTFASW
                     RLQPLTKEYFLWFTLLSMGVFGFFISIDLFTMFMFYEIALIPMYLLIGVWGSGRKEYAA
                     MKLTLMLMGGSAFLLIGILGIYFGSGATTMNLLEIAQLHNIPFAQQCIWFPLTFLGFGV
                     LGALFPFHTWSPDGHASAPTAVSMLHAGVLMKLGGYGCFRIAMYLMPEAANELSWIFLI
                     LTGISVVYGAFSACVQTDLKYINAYSSVSHCGLVLFAILMLNQTAATGAILQMLSHGLM
                     TALFFALIGMI"
     CDS             complement(1137..3068)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_M"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg465_2"
                     /sec_met_domain="Proton_antipo_N (E-value: 1.8e-25,
                     bitscore: 78.9, seeds: 433, tool: rule-based-clusters)"
                     /sec_met_domain="Proton_antipo_M (E-value: 4.4e-87,
                     bitscore: 281.9, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELTILILLLPFLSFLILGIGGKWMSHRTAGAIGTLILGAVVVLS
                     YVTAFQYFSAPRLEDGTFATLIPYNFTWLPFTETLRFDLGILLDPISVMMLIVISTVSL
                     MVHIYSFGYMKGETGFQRYYAFLSLFTMSMLGLVVATNIFQMYLFWELVGVSSYLLIGF
                     YYTKPAAIAASKKAFIVTRFADLGFLIGILIYGYYGGTFGFTPDTVSLISGGASMLPLA
                     LGLMFIGGAGKSAMFPLHIWLPDAMEGPTPVSALIHAATMVVAGVYLVARMFPLFIAYA
                     PDTLHMIAWVGAFTAFYAASVACVQSDIKRVLAFSTISQIGFMMVALGVCTSMDPHHGG
                     LGYMASMFHLFTHAMFKALLFLGAGSIIHAVHSNEMSAMGGLRKYMPITHWTFLIACLA
                     IAGIPPFSGFFSKDEILAACFQYSPAMGWVMTVIAAMTAFYMFRLYYGIFWGAEPPRAS
                     SHSDHSTPHGNLEAAPCRPHESPLAMTFPLIFLAVVTCLAGFIPFGHFISSNGESYSIH
                     LDLSVAVTSVVIAIISIGIATWMYKNAKQPVANALAKRFNGLWTAAYHRFYIDDIYQFI
                     THKIIFRCISTPIAWFDRHVVDGFFNFLAWATNTTSDEIRGLQSGQVQQYAYVFLCGAL
                     ALILLLVL"
     CDS             complement(3156..3464)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg465_3"
                     /sec_met_domain="Oxidored_q2 (E-value: 3.1e-22, bitscore:
                     68.3, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHMEYYLVVSTIMMFAGIYGFFTRRNTLAILISVELMLNATDIN
                     FAVFNRFLFPGGMEGYFFALFSIAISAAETAIAIAIMINIYRNLRSIQVRNLDDLKW"
     CDS             complement(3560..4072)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg465_4"
                     /sec_met_domain="Oxidored_q3 (E-value: 6.5e-37, bitscore:
                     116.4, seeds: 708, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGSTLETVVFYFLAAFIIAMSIMTVTTQRIVRSATYLLFVLFGTA
                     GIYFLLGYTFLGSVQIMVYAGGIVVLYVFSILLTSGEGDRAEKLKRSRFLAGLFTMVAG
                     LAIILFITLKHNFLQTTNLVPLEINIHTIGNALLSSDKYGYILPFEAISILLLACIIGG
                     IMIARKR"
     CDS             complement(4075..4596)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg465_5"
                     /sec_met_domain="Fer4_7 (E-value: 2.1e-13, bitscore: 40.8,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 7.3e-06, bitscore: 16.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LPLASTSKIRIMEYKDQKYTYLGGLIHGISTLATGMKTSIKVYFR
                     KKVTEQYPENRKELKMFDRFRGTLAMPHNENNEHRCVACGLCQIACPNDTITVTSETIE
                     TEDGKKKKILAKYEYDLGACMFCQLCVNACPHDAITFDQNFEHAVFDRTKLVLQLNHAG
                     SKVIEKKKEV"
     CDS             complement(4574..5650)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: NADHdh"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg465_6"
                     /sec_met_domain="NADHdh (E-value: 4.4e-123, bitscore:
                     400.3, seeds: 435, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFDFSIVTNWIHELLLSVMPEGWAIFIECIAVGVCIVALYAILAI
                     VLIYMERKVCGFFQCRLGPNRVGKWGSIQVICDVLKMLTKEIFTPKDADRFLYNLAPFM
                     VIIASFLTFACIPFNKGAEILNFNVGVFFLLAASSIGVVGILLAGWGSNNKFSLIGAMR
                     SGAQIISYELSVGMSIMTMVVLMGTMQFSEIVEGQADGWFIFKGHIPAVIAFIIYLIAG
                     NAECNRGPFDLPEAESELTAGYHTEYSGMHFGFFYLAEYLNLFIVASVAATIFLGGWMP
                     LHIVGLDGFNAVMDYIPGFIWFFAKAFFVVFLLMWIKWTFPRLRIDQILNLEWKYLVPI
                     SMVNLLLMACCVAFGFHF"
     CDS             complement(5776..7392)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Complex1_49kDa"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Complex1_30kDa"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg465_7"
                     /sec_met_domain="Complex1_30kDa (E-value: 5.6e-37,
                     bitscore: 117.1, seeds: 586, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_49kDa (E-value: 1.9e-65,
                     bitscore: 210.5, seeds: 265, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNEERRIMQEIQFIVPAALHDEMLRLRNEKQMDFLESLTGMDWG
                     VADEKDAPEKLRGLGVVYHLESTVTGERIALKTAVTDRERPEIPSVSDIWKIADFYERE
                     VFDYYGIVFVGHPDMRRLYLRNDWVGYPMRKDNDPEKDNPLCMANEETFDTTQEIELNP
                     DGTIKNREMKLFGEEEYVVNIGPQHPATHGVMRFRVSLEGEIIRKIDANCGYIHRGIEK
                     MNESLTYPQTLALTDRLDYLGAHQNRHALCMCIEKAMGIEVSDRVKYIRTIMDELQRID
                     SHLLFYSALAMDLGALTAFFYGFRDREKILDIFEETCGGRLIMNYNTIGGVQADLHPNF
                     VKRVKEFIPYMRGIIHEYHDIFTGNIIAQSRMKGVGVLSREDAISFGCTGGTGRASGWA
                     CDVRKRIPYGVYDKVDFQEIVYTEGDCFARYLVRMDEIMESLKIIEQLIDNIPEGPYQE
                     KMKPIIRVPEGSYYAAVEGSRGEFGVFLESQGDKMPYRLHYRATGLPLVAAIDTICRGA
                     KIADLIAIGGTLDYVVPDIDR"
     CDS             complement(7389..7982)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q6"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg465_8"
                     /sec_met_domain="Oxidored_q6 (E-value: 1.2e-26, bitscore:
                     83.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEITKKPKIKSIPYDEFIDNESLEKLVKELNAGGANVFLGVLDDL
                     VNWGRSNSLWPLTFATSCCGIEFMALGAARYDMARFGFEVARASPRQADMIMVCGTITN
                     KMAPVLKRLYDQMPDPKYVVAVGGCAVSGGPFKKSYHVVNGVDKILPVDVYIPGCPPRP
                     EAFYYGMMQLQRKVKIEKFFGGTNRKEKKPEFMK"
     CDS             complement(7973..8323)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg465_9"
                     /sec_met_domain="Oxidored_q4 (E-value: 5.2e-38, bitscore:
                     119.3, seeds: 391, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFTFLVVVLLTALAFVGVVIALSRAISPRSYNVQKFEAYECGIP
                     TRGKSWMQFRVGYYLFAILFLMFDVETAFLFPWAVVMHDMGPQGLVSILFFFIILVLGL
                     AYAWRKGALEWK"
     CDS             complement(8437..8814)
                     /locus_tag="ctg465_10"
                     /transl_table=11
                     /translation="MKQSLKYGLFLVLALLIHVVSNEAMEDNCRVSPPTYRQEKCYVSQ
                     DHPVHNALERLHYFYSTQSCDMSHADVAHIPTDKSVQLLITYFREYKSQQNTSQTHSLH
                     IPKYFYDPITYYIYGLRKIVI"
     CDS             9074..10678
                     /locus_tag="ctg465_11"
                     /transl_table=11
                     /translation="MKHTLCFITILLGSLLNLYANNENDSLLKVLDKVISERLVYTEKK
                     EATIKELKAKKKEQKTLDDMYRLNSEILHQYETFVCDSAEQYINENIEIAKKLDNKTYL
                     LEGRLQLAFVYSLSGLFIQANDIFKSINCSDLPSHLQALYCWNRIRYYENLIKYTDDAR
                     FASEYLVEKEAYRDTVMSILYDASEEYSKERAIKLQDQGNTKEALKILTKIYQKEKTGT
                     HGFAMMSMGLSRAYRLVGEHELEEKYLILAAMTDIKLAVKENEALLTLAVNLYHKGDID
                     RSYNYIKVALSDAIFYNSRFKNTVIARIHPIIENTYLYRLEKQKQNLRFYILLTSLFVV
                     ALAITLYFTYKQTKIVSRAKKNLNVMNEELVALNKNLDEANLIKERYVGYFMNQCAVYI
                     NKLDEYRKNVNRKIKTGQVDDLYKSSSRPFEKELEGLYTNFDKAFLKLYPNFVEEFNSL
                     LKPEDYYKLDKDQLNTELRIFALMRMGITDVSQIAVFLHYSVQTIYNYKSKVKRMSLLD
                     GNIFEEEVKKLGSLSQK"
     CDS             10869..11393
                     /locus_tag="ctg465_12"
                     /transl_table=11
                     /translation="MDFSELYLTYYSKLVRFAKEFVILEEDAENITQDVFTDLWAKRDS
                     MDRIENMNAYLFRLIKNRCLDHLKHKMFEQKYIESVQTSFEIEMSLKLQSLNRFDVSDI
                     SEGNETEMLVRNAINSLPRKCRDIFLLSRVEGLKYREISERLGISVNTVECQMGIALKK
                     LRVKLNICLAA"
     CDS             11469..11699
                     /locus_tag="ctg465_13"
                     /transl_table=11
                     /translation="MGTNLNKYFAGELTSEEKEVFLLNVKNNGEMREEFIEYQSVVALV
                     DWSFPKDDKELAKQKLSEFMSRIENSENKKA"
     CDS             11707..14256
                     /locus_tag="ctg465_14"
                     /transl_table=11
                     /translation="MNRLNNIILLVVFICTHAHSQQAYFVDGYHGGIYGHYPVKWKTQF
                     IVDQLSKHPDWRICLEIEPETWDTVQIQTPGAYRQLKNVVVTKQVEFTNPTYAQPYCYN
                     ISGESIIRQFQYGIAKINKHFPGVTFTTYSVEEPCFTSCLPQILKLFGFKYAVLKCPNT
                     CWGGYTNAYGGELVNWVGPDGTPILTVPRYACEKLEENSTWQTTAWCNEESYLNACRDA
                     GIEHPVGMCFQDAGWKNGPWLGSGKNTKSNSVYVTWKDYFENISIGKTNDDWHFSQEDI
                     RVNLMWGSQVLQRIAQEVRTSENKIIIAEKMSVIAHLANGYTCVQEDLDEAWRTLMLAQ
                     HHDSWIVPYNGLNKFGTWADQIKRWTDETNTVADKITAASIFSFDNDTINTEKAQGFVR
                     VYNTLGTKRKELVTVELPQEYADFDLEVNDYRNKKVDYSIGKEGGKIRLLFEADVPPFG
                     YSTYRIKQVKTGKRTVSGSEKIINEGEYVVENDMYKIVFDLSKGGIIKSLVAKKEENKE
                     FAKQSGEYSIGELRGYFYDEGKFRSSTEAPAKLTVLRSNIQETKVKLEGKIASHPFVQI
                     ISIAQGEKRIDFDLTINWKKNVGIGEYKENSWRDNRRAYCDDRFKLSVLFPVNLHSPRI
                     YKNAPFDVCESKLDDTFFNSWDQIKHNIILHWVDLAEQEGDYALALFADHTTSYSHGKD
                     YPLGLTAQYSGNGLWGPDYKITGPLKMKYAIVPHRGKWDKAAIATKSDCWNEPLLCSYH
                     SFAKLESRSLVDLKNTGYQVSAANIKDGKIILRLFNAEGDRKQHNITFDMPLSSIEEVD
                     LNGRVIDRKTIKTRTGKSEISISMPRFGLKTFALNLN"
     CDS             14291..15193
                     /locus_tag="ctg465_15"
                     /transl_table=11
                     /translation="MYKASANILIACSFLWLTACSSAGVVTEDLIPTDYVNPFIGASTS
                     VGAAGVYHGLGKTFPGATTPYGMVQVSPNTITGGDNSSGYSDEHKTIEGFAFTQMSGVG
                     WFGDLGNFLVMPTTGELQKIAGKEDGSIKGYRSSYDKATETAKAGYYSVELTDYKIKVE
                     SSATPHCGILQFTFPSNEQSRIQIDLARRVGGTSTSQYVKVLDDYTIQGWMKCTPDGGG
                     WGNGEGNSDYTVYYYAQFSKPLSNYGFWSADIPDEWVRKRDEVVSIPYLTRISQAPVIK
                     DKKELEGKHLGFFTEFPTKE"
ORIGIN
        1 aaatcatacc gatcagggca aagaacaagg ctgtcatcaa tccgtgggaa agcatctgaa
       61 gaatggctcc tgtcgcagca gtctgattca gcatcagaat ggcgaaaagt accagtccgc
      121 agtgagaaac ggaagagtaa gcgttgatgt atttcaagtc tgtctgtacg caagcggaga
      181 atgctccgta aacaacggag atacctgtca gtatcaggaa tatccatgaa agttcgttag
      241 cggcttccgg catcagatac atggcgatac ggaaacatcc gtaacctccc agtttcatca
      301 gtactccggc gtgaagcatg gatacagctg tcggggcgga agcgtgacca tcgggactcc
      361 atgtgtggaa cgggaaaaga gcacccagca caccgaaccc gaggaaggta agcgggaacc
      421 agatacattg ctgtgcaaaa ggaatattat gtagctgtgc tatttccagc aggttcatgg
      481 tggtagctcc cgaaccgaaa tagattccga gaataccgat cagcaggaaa gcggaaccgc
      541 ccatcagcat aagggtcagc ttcatggctg catattcttt acgtcccgaa ccccatacac
      601 cgatcagcag gtacatagga atcagcgcga tttcgtagaa catgaacatg gtgaataagt
      661 cgatggatat aaagaatccg aagactccca tagacaacag tgtgaaccaa aggaaatatt
      721 cttttgtcag aggctgcaga cgccaggagg cgaaagtacc tgtgaataca ataacggcag
      781 acaataacaa catggctacc gaaataccgt caacgcctac cgagtaggag atgtgaagcg
      841 gtgcatacca gagtgtatcc gcacggaata gcatttctgc cgtgttgccg gcactgcgtt
      901 ctcccaaata cataaaggta agtacgacgg aggcaatcag aagtgccgat gcgccggtaa
      961 ccataacccc ccgaatcgct ttgattcccc gtgctgccca aagtccggca agcatcagta
     1021 aggggatgag tacgaagatt gataaaaaat tcataattga attattaagt tttaagtatt
     1081 aattcgcagc gacttgttgc gcagcttaat atctaatacc tgatagttaa tacttgctat
     1141 agaactaaca gcaggataag cgccagcgct ccgcaaagga acacgtatgc gtattgctgt
     1201 acctggccgc tttgaagacc acgtatctcg tcgcttgtcg tattcgtagc ccatgccagg
     1261 aaattaaaga atccatccac tacatgacgg tcgaaccatg cgataggagt cgaaatgcaa
     1321 cggaagatga tcttatgcgt aataaactgg tatatatcat caatataaaa acgatgataa
     1381 gcagctgtcc acaatccatt gaaccgtttg gcaagtgcat tggcaacagg ctgtttggca
     1441 ttcttataca tccatgtggc aatcccgata gaaataatcg caattacaac gcttgtgaca
     1501 gctaccgaca gatcgaggtg aatagagtaa gactccccat tcgaactgat aaaatgtccg
     1561 aaaggaatga atcctgcaag gcaggtaaca accgccagaa atatcaacgg aaaagtcata
     1621 gccaacggac tctcatgcgg gcgacaaggt gccgcttcca agtttccgtg cggtgtgcta
     1681 tgatccgaat gggagcttgc ccggggcggc tcggcccccc agaagatgcc gtagtagagg
     1741 cggaacatat agaaggcggt cattgcggcg attactgtca tcacccaacc cattgcaggg
     1801 ctatattgga agcaggcagc caaaatctca tcttttgaga agaaaccgga gaacggagga
     1861 ataccggcaa tggcgagaca ggcaatcagg aatgtccagt gagtaatagg catgtatttg
     1921 cgtagtcctc ccatggctga catttcgttg gaatgtactg catggataat gctgccggca
     1981 cccaagaaga gtaatgcctt aaacatggcg tgtgtgaaga ggtggaacat ggaagccata
     2041 tatcccagtc ctccgtggtg cgggtccata gaagtacaaa cgcccagtgc taccatcata
     2101 aaaccaatct gtgaaatggt cgagaaggcc agcacacgtt tgatatccga ttgtacgcaa
     2161 gccacgcttg ctgcataaaa ggcggtgaaa gcacctaccc aggcaatcat atgtaaggtg
     2221 tccggtgcat aagcaatgaa aagcgggaac atacgcgcta ccagataaac gccggcaact
     2281 accatcgtag ccgcatggat caaggcactg acaggagtag gaccttccat ggcatcgggc
     2341 agccagatat gcaacgggaa catggcactc tttccggcgc caccgataaa catcagtccc
     2401 aaagccaatg gaagcatgga agcgccgcca ctgatcaatg ataccgtatc cggtgtgaag
     2461 ccgaatgtgc caccgtagta tccgtaaatc agaataccga taaggaagcc taagtctgca
     2521 aagcgggtga caatgaacgc tttcttggaa gcggcaatgg cagcaggctt tgtatagtaa
     2581 aaaccgatca gcagataaga actgacaccc accagttccc agaaaagata catctggaaa
     2641 atgtttgtgg caaccaccag tcccagcata gacattgtaa acagggacag gaaggcgtaa
     2701 taacgttgaa agcctgtctc gcctttcatg taaccgaagg agtagatatg caccatcagt
     2761 gacacggtag agatgacaat cagcatcatc acggatatgg gatcgagcag aatgcccaga
     2821 tcaaatcgta aagtctcggt gaaaggaagc cacgtaaaat tataaggtat caacgtggca
     2881 aatgttccgt cttccaaacg aggggcggag aaatattgga aagccgtaac gtacgacagt
     2941 actactactg ctcccagtat cagcgtaccg atagcacccg ctgtccgatg agacatccat
     3001 tttcctccga ttcccagaat gaggaaggag aggaagggaa gaaggagtat tagaattgtt
     3061 agttccatac agtttatttt aattacttgt tttattattg ttcatattta tcacgatatc
     3121 catccgaatg gaaattgggt cgtgccgctt tggcactacc acttcagatc gtccagattg
     3181 cggacttgaa tgcttcggag gttgcggtaa atgttaatca tgatggcgat agctatagcc
     3241 gtttccgcag ccgaaatagc gatggaaaag agtgcaaaga aatagccttc catgcctccc
     3301 ggaaagagaa aacggttgaa cacggcgaag ttgatgtccg tggcgttcag cattaactct
     3361 acagaaatca ggatagccag cgtattacgg cgggtaaaga acccatagat tcctgcaaac
     3421 atcatgatgg tagaaactac cagataatat tccatgtgta tcatatctga aattattagg
     3481 ttttaagtaa taagtattaa ttccttgcgg ttcattgcgc agcctaatac ctgatactta
     3541 atagttaata cttacttatt tatctctttc gggcgatcat gataccaccg atgatacaag
     3601 ccagcaataa aatactgatt gcttcgaaag gcaatatata accatatttg tcactgctta
     3661 ataaagcatt accaatggtg tggatgttta tttccagcgg aaccaggttg gtcgtttgca
     3721 ggaagttatg cttcagggtg ataaacaaga taatcgctaa accggcaacc atcgtaaaga
     3781 gtcctgccag aaacctgctt cgtttcagtt tctcggcgcg gtcaccttct ccactggtca
     3841 gcaggatgga gaatacataa agaacgacga taccaccggc ataaaccata atctggacag
     3901 accccagaaa tgtgtaaccc agcaggaaat agatgccagc cgtgccgaag agcacgaaga
     3961 gcagataggt ggctgagcgg acaatacgtt gggtagtcac cgtcatgatg gacatagcaa
     4021 taataaatgc tgccaaaaag tagaatacta ctgtttcaag tgttgatccc atatctaaac
     4081 ttcttttttc ttttcaatta ctttactacc ggcatgattc agttgcagaa caagcttcgt
     4141 ccggtcaaag acggcatgtt cgaagttctg gtcgaacgtg atggcgtcat gcggacaagc
     4201 gttgacacac agttggcaga acatacaagc tccgaggtca tattcatatt ttgccaggat
     4261 tttcttcttc ttgccgtctt cagtctcgat cgtttcgctg gttacggtga ttgtatcgtt
     4321 cggacaagct atctgacaca atccgcaggc tacacagcgg tgttcgttat tctcattgtg
     4381 gggcattgcc agtgtaccac ggaaccggtc gaacattttc agctctttcc ggttttcagg
     4441 atactgttcg gttaccttct tacggaagta taccttgata ctggttttca tacccgttgc
     4501 cagagtgctg ataccatgta tcagtcctcc caagtacgta tatttttgat ctttatattc
     4561 cataattctt attttagaag tggaagccaa aggcaacaca acatgccatt aataataggt
     4621 ttaccataga aattggaacc agatatttcc attccagatt cagaatctgg tcgatacgca
     4681 ggcgtgggaa agtccatttg atccacatta agaggaacac aacgaagaat gctttggcaa
     4741 agaaccagat gaagccggga atatagtcca taacagcgtt gaatccgtcc aaaccgacga
     4801 tatgcaatgg catccagcct cccaaaaaga tggtagcggc cacgctggct acgataaaca
     4861 gattcagata ttccgccaga taaaagaaac cgaagtgcat accggaatat tccgtatgat
     4921 atccggccgt caattcactt tccgcttcgg gaaggtcgaa cgggccacgg ttacattctg
     4981 catttccggc aatgagatag atgatgaaag cgataacggc aggaatatgt cctttgaaga
     5041 taaaccatcc gtcagcctgt ccttctacga tttcggagaa ctgcatggtg cccatcagta
     5101 cgaccatcgt catgatgctc atacccactg acaactcata actgatgatc tgtgcgccgc
     5161 ttcgcatggc accgatcagc gaaaacttgt tgttactacc ccaaccggca agcagaatac
     5221 ctaccacacc gatgctggaa gcagccagca ggaagaatac gcccacatta aaattcagaa
     5281 tttccgctcc tttattaaaa ggaatacaag cgaaagtgag gaacgaggcg ataatcacca
     5341 tgaatggagc cagattgtag aggaagcggt cggcatcctt cggagtgaaa atctccttgg
     5401 tcagcatctt gagtacgtcg catatcactt gaatagaacc ccatttaccg acacggttcg
     5461 gaccgaggcg gcactggaag aaaccacaga ctttgcgttc catgtaaatc agtacgatag
     5521 ccagaattgc atatagtgca acgatgcaca cgccgacagc tatgcactct ataaagatgg
     5581 cccatccctc cggcataacg gagagcagca gctcatgtat ccagtttgtt actatactaa
     5641 agtcgaacat atatatttta attattaggt tttaagtatt aagtattaat tccatgcgga
     5701 atatagcgta tatcatattg catagtcggt taatacttac tactttatac ttaatacttg
     5761 ttttttatct tttgtttatc ggtcgatgtc cggaactaca tagtccagtg ttcctccgat
     5821 ggcaatcaag tcggcaattt tcgctccgcg gcaaatcgtg tcgattgcag caacaagtgg
     5881 caatcccgta gcacgatagt gcaggcgata aggcatcttg tcaccctgac tttcgagaaa
     5941 gactccgaat tctccgcggc ttccttctac ggcggcataa taactgcctt cgggaacgcg
     6001 gatgatcggt ttcatctttt cctgatacgg gccttcggga atgttgtcta tcaactgctc
     6061 tataatcttc agactctcca tgatttcgtc catacgcacc agataacggg cgaaacagtc
     6121 tccttccgta taaacaattt cctggaagtc caccttgtca tatacaccgt acggtatccg
     6181 cttacgtaca tcgcaagccc aacccgaagc acggcctgta cccccggtgc aaccgaatga
     6241 gattgcatct tcacggctta acactccgac gcccttcata cggctctgag cgataatgtt
     6301 gccggtaaat atgtcgtggt attcgtgaat gatacctctc atataaggga taaattcttt
     6361 tacccgcttg acgaagttag gatgaaggtc ggcctgtaca ccgccgatgg tattgtagtt
     6421 catgatcaga cgtccgccgc aagtctcttc aaaaatatcg agaatttttt cacggtcacg
     6481 gaatccgtag aagaaagcag tcagtgctcc aaggtccatg gcgagggcgg agtagaacag
     6541 taagtgagag tcgatacgtt gcagctcatc cataattgta cgaatgtatt tgacacggtc
     6601 actcacttcg atgcccatcg ctttctcgat gcacatacac aaagcgtgac ggttctgatg
     6661 tgcgcccaga tagtcgaggc ggtcagtcaa tgccaatgtc tgcggatatg taagactctc
     6721 gttcattttc tcgatacccc gatggatata accgcagttt gcatcgatct tacgaataat
     6781 ttcaccttca agagaaacgc ggaaacgcat tacaccgtga gttgcagggt gttgcggacc
     6841 gatgttgact acatactctt cttctccgaa gagtttcatt tctctgtttt tgattgttcc
     6901 gtccggatta agttctattt cctgtgttgt atcgaacgtc tcttcgttag ccatacaaag
     6961 cggattatct ttctccggat cattatcttt acgcatgggg tatcctaccc agtcattacg
     7021 taagtaaagg cggcgcatat cgggatggcc tacgaaaaca atgccatagt agtcgaacac
     7081 ttcacgttcg tagaaatcgg ctattttcca tatatcgctg actgacggaa tttccggtcg
     7141 ttcacggtcg gtaacggctg ttttcagtgc tatccgttct cccgtaacag tcgattccag
     7201 atggtagaca acgcctaaac cacggagttt ctccggtgcg tctttttcgt ctgctactcc
     7261 ccagtccata ccggtgaggc tttcaaggaa gtccatctgt ttttcatttc gcaagcgcag
     7321 catttcgtcg tgtaacgctg cagggactat aaattgtatt tcttgcataa ttcttcgttc
     7381 ctcattcttc atttcataaa ttccggtttc ttctcttttc tgttcgttcc accaaagaat
     7441 ttctctattt tcactttgcg ttgtagttgc atcatgccgt aatagaaagc ttccgggcgc
     7501 ggcggacatc cggggatata tacatctacc ggaagaatct tatccactcc gttcaccaca
     7561 tgataagatt tcttgaaagg gcctccgctg acagcacatc cgcctacggc aaccacgtat
     7621 ttcgggtcgg gcatctgatc gtacaaacgt ttcagtaccg gtgccatctt attggtgatt
     7681 gttccgcaga ccatgatcat atcagcctga cgcgggctgg cacgtgctac ttcaaacccg
     7741 aaacgggcca tatcataacg cgcggcaccc agtgccatga attcgatacc gcaacagctg
     7801 gttgcgaaag taagcggcca cagtgaattg ctgcgtcccc agttgacaag gtcgtccaaa
     7861 accccgagga aaacgttcgc tcctccggca ttaagttcct tgaccaactt ttccaatgat
     7921 tcattgtcga tgaattcatc atacggaatt gattttattt tcggtttttt ggttatttcc
     7981 attccaaagc tcctttcctc caggcataag caaggcccag aaccaaaata ataaagaaga
     8041 agagaatact aacgagcccc tgaggtccca tgtcatgcat tactactgcc caagggaaca
     8101 gaaaagctgt ttccacgtcg aacatcagga acaggatggc aaacaggtag taacctacac
     8161 ggaactgcat ccatgattta ccacgcgttg gtataccaca ttcataagct tcaaactttt
     8221 gtacattgta cgaacgtggt gaaatagctc gtgaaagggc tattactaca ccgacaaaag
     8281 cgagcgctgt cagtaaaaca acaactaaaa atgtaaaatt cataatttca atagctgttt
     8341 agattgaata ttatatagaa ataaacaatt agtttctcca cacccggatg aaaccaactg
     8401 taatgaattg acgaataaga taatggattg taccgtctaa atgacgatct tccttaaacc
     8461 atatatataa tatgtaatag gatcgtaaaa gtacttggga atatggagtg aatgagtctg
     8521 agacgtgttt tgctggcttt tgtattcacg gaaataagta atcagcaatt gcacgctttt
     8581 atctgtaggg atgtgtgcaa catccgcatg actcatatca caagactggg tagaatagaa
     8641 ataatgaaga cgttcaagag cattatgaac aggatgatcc tgagatacgt agcacttctc
     8701 ctggcgatat gtcggggggg atactctgca gttatcttcc attgcttcat tggaaacaac
     8761 atggatcagc aaagcaagta ccagaaatag tccgtatttt aagctttgtt tcatctttct
     8821 cttttaacgg ctgcaaatat aggattaata ttcatgtttt ttgcaaagtc ggggttacaa
     8881 aaaagtattt tttaacttgc tttatttcaa gtccgttttt atttcagtgc tactttggag
     8941 aatcttcttc ttttatggta tatatccgtt cttatttggt taaaagatgt aataaaaaga
     9001 acgatttacg ttctttttga cgaattaccc aaagaaaatt catttttttg caaattgtat
     9061 ataacacatt gatatgaaac acacactttg ctttataaca atcctactgg gttctttgtt
     9121 gaatctttat gcaaataacg agaatgattc tctattgaaa gttttagata aagtgatttc
     9181 tgagcgtctt gtgtatacag aaaagaagga agctactatc aaagagctga aagcaaaaaa
     9241 gaaggaacaa aagaccttgg acgatatgta tcgtctgaat tccgagattc tccatcaata
     9301 cgaaacgttt gtctgcgatt ctgcggaaca gtacattaat gagaatattg agatcgctaa
     9361 gaaactggat aataaaacct atttgctgga aggaaggctg caactggctt ttgtttattc
     9421 cttatcgggg ttgtttattc aagctaatga tattttcaaa tcaatcaatt gttcggattt
     9481 acctagtcat ttacaggctt tgtattgttg gaatcgtatt cggtattatg aaaatttgat
     9541 taaatataca gatgatgctc ggtttgccag tgaatatttg gttgaaaaag aagcgtatcg
     9601 agatacagtt atgagtatct tgtatgatgc atcggaagaa tattcgaaag aaagagctat
     9661 aaagcttcag gatcagggaa atacaaaaga agcacttaag atactgacta aaatttatca
     9721 aaaggaaaaa acaggaactc atgggtttgc aatgatgtct atggggctat caagagcata
     9781 tcggctggtc ggagagcatg aattggaaga aaagtatctt atattagctg ctatgaccga
     9841 tataaaactg gcagtgaaag aaaatgaggc tttgttgact ttagccgtga atttatacca
     9901 taaaggagat atcgatagat cttataatta tattaaagta gcactgagtg atgctatctt
     9961 ctataattcc cgttttaaga atacggtaat agctcgtatt catcctatta tagaaaatac
    10021 ttatttatat aggctggaaa agcaaaagca gaatcttcgt ttttatattt tgctcactag
    10081 tttgtttgtt gtggctcttg ctatcacttt gtattttact tataaacaga ctaagattgt
    10141 ttcccgtgca aagaagaatc tcaatgttat gaatgaagag ttagttgcat tgaacaagaa
    10201 tttggatgag gctaatttaa taaaagaaag atatgtaggc tatttcatga accagtgtgc
    10261 cgtttacatt aataaactgg atgaatatag gaaaaatgta aatcgaaaaa taaaaaccgg
    10321 acaagttgat gatttataca aatcttcttc tcgtcctttc gaaaaagaat tggaaggatt
    10381 atataccaat tttgataagg cgttcttaaa attgtatcct aattttgtcg aagagtttaa
    10441 ttcattgttg aaaccggaag attattataa actggataaa gaccagttga atacagaatt
    10501 gcgtattttt gctttgatgc gaatggggat tacagatgtt tcgcaaattg ctgttttttt
    10561 gcattactca gtacaaacga tctataatta taagagtaaa gtgaagagaa tgtctttatt
    10621 ggatggaaat atcttcgaag aagaggtgaa aaagcttggt tctttgtccc aaaaatgatt
    10681 ctatttggtt taccaaaacc ttaaaatggt tgtttgttaa tgcgttgaat attaatgtat
    10741 tatctagaag agatgttcaa aaacgtctac tttatagcct acttccaata aggagtaggc
    10801 ttttttcatc tctatatttg catcacaaga tttttgataa ctgaatacta atctaaagaa
    10861 acacagctat ggatttttca gaattgtatc ttacttatta ttcaaaactg gttcggtttg
    10921 caaaagaatt tgtaatactg gaagaggatg cagaaaacat aacacaagat gtgtttaccg
    10981 acttatgggc gaaacgtgat tctatggatc gcattgaaaa tatgaacgcg tatcttttca
    11041 gattaataaa gaatagatgc ttggatcatt tgaaacataa aatgtttgaa cagaaatata
    11101 ttgaatcagt tcaaacctct ttcgaaatag aaatgtcctt gaaattacaa tctttaaata
    11161 ggtttgatgt gtctgatatc tcggaaggaa atgaaacgga aatgctcgtt cgtaacgcaa
    11221 tcaatagtct gcctcgaaaa tgtcgtgaca tatttttatt aagtcgtgtc gaagggttaa
    11281 aatatagaga aatctcagaa cgtttgggta tttcagtaaa tactgtagaa tgtcagatgg
    11341 ggatagcact caaaaagtta agggtaaaac taaatatttg ccttgcagca tgagttttaa
    11401 taattttatt gatatttttt taggggtatt tactgggata atcgttcttt tgtaaaaagg
    11461 aacgaataat gggaactaat ttaaataaat attttgcagg tgaattgact tcagaagaaa
    11521 aggaagtctt ccttctgaat gtgaagaata atggggaaat gcgcgaagaa tttattgagt
    11581 atcagagtgt tgttgctctt gtggattggt cgttccctaa agatgataaa gaacttgcta
    11641 agcaaaaact atctgaattt atgagtcgga tagagaatag cgaaaataaa aaggcttaaa
    11701 aataccatga atagacttaa taacatcata ttactagtcg tctttatatg tacgcatgct
    11761 cattcgcaac aagcttattt tgttgatgga tatcatggag ggatatacgg gcattatccg
    11821 gtgaagtgga aaactcagtt tattgtcgac cagttatcca agcatccgga ttggcgaatt
    11881 tgtctggaaa tagagcctga aacatgggat acggtgcaaa tacagactcc cggagcctat
    11941 cgacaattaa aaaacgtagt agtaactaag caggtagagt ttacaaatcc tacttatgct
    12001 cagccttatt gttataatat atcgggcgaa agcattatac gtcagtttca atatggtatt
    12061 gctaagataa ataaacattt tccgggagtg acttttacca cttattctgt ggaagaaccc
    12121 tgtttcacaa gttgtttgcc tcagatattg aagttatttg gttttaagta tgccgtactc
    12181 aaatgcccga atacttgttg gggaggatac actaacgctt atggcggcga attggtcaat
    12241 tgggtaggcc cggatggaac tcccattctt actgttcctc gctatgcttg cgagaaattg
    12301 gaagagaatt ctacttggca gacaactgct tggtgtaatg aagaatctta tctgaatgct
    12361 tgtcgtgatg cagggattga acatcctgtg ggaatgtgtt tccaagatgc cggatggaaa
    12421 aatggtccat ggttaggaag tggaaagaat acaaaaagta attcagttta tgtgacgtgg
    12481 aaagattatt ttgaaaatat ttccattggt aaaacgaatg atgactggca tttctcgcag
    12541 gaagatatac gtgtaaactt aatgtgggga agccaagtgt tgcagagaat tgctcaagaa
    12601 gtacgtactt ctgagaataa aataataata gcagagaaga tgtctgttat tgctcatctt
    12661 gccaatgggt acacttgtgt tcaggaagat ttggatgaag catggcgtac tttgatgctt
    12721 gcgcaacatc atgattcttg gatcgtacct tacaatggcc taaataaatt tggaacctgg
    12781 gcggatcaaa taaagcgatg gacagatgag acaaatactg tggctgataa aattacagct
    12841 gcttctatat tcagttttga taacgatact attaatactg aaaaagccca gggatttgta
    12901 cgtgtttata atacattggg aacaaaaaga aaagaactgg taactgttga actccctcag
    12961 gaatatgcag actttgattt ggaagtcaat gattatagaa ataaaaaagt tgattattca
    13021 ataggaaaag aaggtggaaa aataagattg ttgtttgaag cagatgttcc tccctttggt
    13081 tactccacat atcgtattaa acaagtaaag acaggtaaaa gaacggtttc aggaagcgaa
    13141 aagattataa atgaaggaga atatgtggtt gaaaatgata tgtataaaat tgtttttgac
    13201 ttgtcgaagg gaggaattat taaaagcctt gtagcaaaaa aagaagaaaa caaagaattt
    13261 gccaaacaat cgggtgaata ttctataggt gaattgagag gctattttta tgacgaaggc
    13321 aagtttcgct cttctacaga agctccggct aagctgacgg ttttgcgaag taatatacaa
    13381 gagacaaagg taaaactgga agggaaaata gcttcacatc cttttgtaca gattataagc
    13441 attgctcaag gggagaagcg tatcgatttt gaccttacta ttaattggaa gaaaaatgta
    13501 ggtattggag aatataaaga aaatagttgg cgggataatc gcagagctta ttgtgatgac
    13561 agatttaagt taagtgtact tttccctgta aatcttcatt ctcctcgtat ttataaaaat
    13621 gcgccgtttg atgtttgtga aagtaagtta gatgatactt ttttcaatag ttgggatcag
    13681 attaagcata acattattct tcattgggtt gatttggcag aacaggaagg agattatgca
    13741 ttggctttat tcgcagacca tactacttcc tattcacacg gaaaagatta tccgttagga
    13801 ctgactgccc aatattctgg taatgggctt tggggacctg actataagat cacgggaccg
    13861 ttgaaaatga aatatgctat tgttcctcat cgtggcaaat gggacaaggc tgctatagcc
    13921 acgaagagcg attgttggaa tgaaccattg ttatgttcct atcattcatt tgcaaaattg
    13981 gagtcaaggt cactggtaga cttaaaaaat accggttatc aggtgagtgc agccaatata
    14041 aaagatggaa aaataatctt gcgattgttt aatgcggaag gtgacaggaa gcagcataat
    14101 attacttttg atatgccgct gtctagtata gaagaagtag atctgaatgg tagagttata
    14161 gatagaaaga caataaaaac acgtaccgga aaatctgaaa ttagtatttc tatgcctcgt
    14221 ttcggtctaa agacatttgc tttgaacttg aattgaacat attctaataa tagtaaactg
    14281 taatattttt atgtataaag ctagcgctaa tattttaata gcttgctctt ttttgtggct
    14341 gactgcttgt tcttcagcag gagtagtaac agaagattta attccgactg attatgtaaa
    14401 tccttttata ggagctagta ccagtgtagg agctgccggt gtttatcatg gattaggtaa
    14461 gacatttcct ggcgctacta ctccttacgg tatggtacaa gtaagtccca atactataac
    14521 cggaggtgat aatagttccg gttatagtga tgaacacaaa accattgaag gctttgcctt
    14581 tactcagatg agtggagtgg gctggtttgg ggatttagga aatttcctgg tgatgcctac
    14641 aacgggcgaa ctgcaaaaaa tagcgggtaa agaagatggt agtataaaag ggtatcgttc
    14701 ttcttatgat aaagctaccg aaacagctaa agcgggatat tattcggtag aactgactga
    14761 ttataagatt aaagtagaga gcagtgcgac acctcattgt ggaatattgc aatttacttt
    14821 tccttcgaat gaacaatctc gtattcagat agacctggca cgtagagtgg gagggacttc
    14881 tacttcgcaa tatgtgaaag tattggatga ttataccatt caaggctgga tgaagtgtac
    14941 acctgatggg ggtggatggg gaaatggtga gggaaattcc gattacacag tttattatta
    15001 tgcacaattt agtaaaccac tgagtaatta tggcttttgg agtgcggata ttcctgatga
    15061 atgggttcgg aagcgtgatg aagtggtaag tattccctat ctgacacgta tatcacaagc
    15121 tccggtcatt aaagataaga aagaactgga aggaaagcac cttggcttct tcacagagtt
    15181 tcccacaaaa gaggg
//
