LOCUS       gnlProkkaOJCDILHJ_121  12582 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OJCDILHJ_121.
ACCESSION   gnlProkkaOJCDILHJ_121
VERSION     gnlProkkaOJCDILHJ_121
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 19:25:48
            Original ID  :: gnl|Prokka|OJCDILHJ_121
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 12621
            Orig. end    :: 25203
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12582
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10348]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10348
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12582
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12582
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(556..1221)
                     /locus_tag="ctg121_11"
                     /transl_table=11
                     /translation="MFEIKVSQEIKNACPVFAGAAVYAAVKNTAYCDGLWKEINTFTED
                     LTTTTQMADIKLQPVIAATREAYKRCGEDPGRYRPSAEALRRRLMRGIPLYQIDTLVDL
                     INLVSLRTGHSIGGFDADKIQGKHLELGIGKAEEPFEGIGRGILNIEGLPVYRDSFGGI
                     GTPTSDHERTKMDVGTTHILAIVNGYNGKEGLKEAAEMIQSLLRDYAGSDGGELIYFE"
     CDS             complement(1261..2046)
                     /locus_tag="ctg121_12"
                     /transl_table=11
                     /translation="MLGYESLSSYSNISHFVTTRQGGCSEGNYASFNCTPYSGDEAEKV
                     RRNQTLLMEGMSQIPEELVIPVQTHETNCLLIGDAYLSASSQQRQEMLHGVDALITREP
                     GYCLCISTADCVPVLIYDKKHSAIAAIHSGWRGTVAYIVRDTLLRMEKEFGTSGEDVVA
                     CIGPSISLASFEVGEEVYEAFQKNGFDMPRISIRKEETGKHHIDLWEANRMQILAFGVP
                     SGQVELARICTYIHHDEFFSARRLGIKSGRILSGIMIHK"
     CDS             complement(2070..3236)
                     /locus_tag="ctg121_13"
                     /transl_table=11
                     /translation="MAESNFVDYVKIYCRSGKGGRGSTHMRREKYCPNGGPDGGDGGRG
                     GHIILRGNRNYWTLLHLKYDRHAMAGHGESGSKNRSFGKDGADKVIEVPCGTVVYNAET
                     GEYLCDVTDDGQEVILLKGGRGGQGNSHFKTATRQAPRFAQPGEPMQEMTVIMELKLLA
                     DVGLVGFPNAGKSTLLSAISAAKPKIADYPFTTLEPNLGIVSYRDGKSFVMADIPGIIE
                     GASQGKGLGLRFLRHIERNSLLLFMVPADSDDIRKEYEVLLNELRTFNPEMLDKQRVLA
                     ITKSDMLDQELMDEIEPTLPEGVPHIFISSVSGLGISVLKDILWEELNKESNKIEDIVH
                     RPKDVTRLQQELKDMGEDEELDYEYEEDADDDDDDLDYEYEEEDWEEK"
     CDS             complement(3249..3818)
                     /locus_tag="ctg121_14"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTE
                     LGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLAER
                     GQDVSVMLDLEVPEDELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTSPLIDWYKNE
                     KKYQHINGLGTMDGIFADICEAVDKL"
     CDS             complement(3852..4388)
                     /locus_tag="ctg121_15"
                     /transl_table=11
                     /translation="MDTIQIKDKQFTVSIKEQDIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGVTSTGVIKEVIGLNEDIAGRTVVIVEDI
                     VDTGLTMQRLLDTLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVVD"
     CDS             complement(4430..5974)
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 51.3; E-value: 1.1e-15)"
                     /gene_kind="transport"
                     /locus_tag="ctg121_16"
                     /transl_table=11
                     /translation="MSSLKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASSLNNTD
                     LAHWMMYGGLGFMILGNGCFKPTVSSLVGQLYEPGDKRLDAAYTIFYMGVNVGSFAAPL
                     ICGFLGDTGNPQDFKWGFLASGIMTLFTVVLFETQKNKYLFSPSGEPIGIVPDARREKK
                     GDKAEHISHPKMDKRTKVRNIIIITALTVALIAFFSYAFSDDWISVGIFTACIVFPVLI
                     LLDGSLTKVERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTDRSIFGWEMPASW
                     FQSFNPLFVVILAYIMPGIWSFLNKRNMEPASPTKQAIGLLLLSLGYLFICFGVKDAIP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAG
                     MLSGLYPEDGKVKSILGYQIATMYDFFMLFVIMSGVASLILFLLSKKLQKMMHGVE"
     CDS             complement(6167..6316)
                     /locus_tag="ctg121_17"
                     /transl_table=11
                     /translation="MFTLCHELGLTFEDVAIAIGWLARENKILLRKKEGMLYASIENVE
                     FTFG"
     CDS             complement(7131..7418)
                     /locus_tag="ctg121_18"
                     /transl_table=11
                     /translation="MLRCQCGRYELGADFMESYFFHHLYQFFVGLAVGRKFAFRVEEIY
                     FDLVSFFRHHAGDGEGVSAIIARSGKDGDRCFRIPSVGDGFSQRLCGMLH"
     CDS             7422..8564
                     /locus_tag="ctg121_19"
                     /transl_table=11
                     /translation="MIDGLFGSGLNKPLSGGFAAVVKYINASPAMVVSIDIPSGLMGEE
                     NTFNVKSNIIRADVTFSLQLPKLAFLFAENTEFVGEWELLDIQLSEEGIEETETNYEML
                     EIEEIRSLIKPRQQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTVHAPLC
                     NNDILQTSAPEAMVETDVSETCFAVPTDTDDYQAVGIGPGLGRSEETEAALIEQLEHCQ
                     TPTVVDADALNILANHRHTLTHLPKGSILTPHPKELERLVGKCQDSYERLMKACELAHT
                     AKVHIILKGAYSAIITPEGKCYFNQTGNPGMATGGSGDVLTGVILALLAQGYPAEDAAK
                     IGTYIHGLAGDIAQKKQGMIGLIASDIVTCLPTAWRLVSE"
     CDS             8671..9702
                     /locus_tag="ctg121_20"
                     /transl_table=11
                     /translation="MATSAYAQTEVLTGVTRGKDYGVVYALPKTQIEIEIKANKVNYKP
                     GEFSKYADRYLRLTNVSAEPEEYWELNSVKVKPVGVPNSEATYFVKLKDKTVAPLMELT
                     EEGLIKSINVPYSSNNAKNAANNAVAPQRKANPRDFLTEEILMASSTAKMAELVAKEIY
                     NIRESKNALLRGQADNMPSDGAQLKIMLDNLNLQEEAMTEMFSGVRDKEEKTFTVRLTP
                     DKEFENEVAFRFSKKLGVVANNDLAGTPFYISLKDLKTVKIPQEDGKKKKEMDGIAYNV
                     PGQAMVTLTDGKKKLYEGEIPVTQFGIIEYLAPVLFNKNSTIKVYFDPVTGGLLKVDRE
                     EGK"
     CDS             9724..10011
                     /locus_tag="ctg121_21"
                     /transl_table=11
                     /translation="MGGEGHMLDMIRRLKDGKEASRLRRERRNDKLGRLRRNNDPYLLP
                     DTTPEEMERIIKDSEKKKEKDNSYFVWGTLIIMGVLIGCAVLLWAIFFNG"
     CDS             complement(10001..10348)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg121_22"
                     /sec_met_domain="PF05402 (E-value: 9.1e-18, bitscore: 55.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 3.8e-10, bitscore:
                     30.2, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATKEKINLLEVIPCRNEHIKAEQEGETIVLSFPRFKRSWMSRYL
                     LPKGMSKDIHVRLEEHGTAVWNLIDGQRTVREIIEKLADHFQHEAGYESRVSTYLSQLQ
                     KDGFIKWIIIH"
     CDS             complement(10396..11784)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 91.3; E-value: 8.1e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg121_23"
                     /transl_table=11
                     /translation="MTEQLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AITTTFPEGAMLFGFKMQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGVFHTNIPAPILFCLVMLCVGTIAFFIYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMVIGSVMLIFVHTMFAL
                     PILNIWWFATVIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNSYCKGPVVDGAQTYDYTLPMAIFAMFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             complement(12075..12470)
                     /locus_tag="ctg121_24"
                     /transl_table=11
                     /translation="MYLLFIILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSVATAYVVPSSSAAKDVLLEQAQKEQQTNPYNMPTGTAAP
                     QTDATAPAESAPATEAPATETPAPAAE"
     CDS             complement(12477..12581)
                     /locus_tag="ctg121_25"
                     /transl_table=11
                     /translation="MIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
ORIGIN
        1 atgtgccctc cttcagattg aaaataagat tcggattaaa atgctgaccg ttaatgcggg
       61 tttcaaaatg cacatgctcc gtagtagcac ggccggtacg tccggtcagt ccgataggtt
      121 gtccggcttt caccgtatct ccgctctgta ccaaattctt gaagttatga ctgtaaatcg
      181 tttccagccc gttcgcatga cggactacaa ccaaatttcc gtaagcataa tatggcttcg
      241 acatacgtac gactccatca aaagcagcac gaatcgtatc tttggcacac gtctttatat
      301 ctgctcccga atgtcctccg cgagttccgt aagcggaaat aactttggct cccggtaagg
      361 gaaaagcata ttcatgctct tgcaaagaat ccaaatgcag atatatatga ttgcttttcg
      421 caaaaagtcc gggagtagca acccgtacat gattcacctc catagaagaa aaagaggatt
      481 tactttgcgc ataagcaaga gttggtaaaa gcaggactgt caataaaata agtatgttct
      541 tcatgtattc ctttattatt caaaatagat aagctcgccg ccatccgatc cggcataatc
      601 cctcagtaag gattgaatca tttcagcagc ttcctttaat ccctcttttc cgttataccc
      661 gttgactatc gcgagaatat gagtagtccc gacatccatc ttcgtacgtt cgtggtcgct
      721 tgtcggtgtc ccgattcctc caaaagaatc tctgtacacc ggcaatcctt caatgttcaa
      781 aatgccccga ccgatacctt cgaaaggttc ttccgctttg ccaatgccaa gttcaagatg
      841 tttaccctgt atcttatccg catcgaagcc accgatagaa tgtccggtac ggagagaaac
      901 cagattgata aggtcaacca aagtatcaat ctgatacaaa gggatgccac gcatcaggcg
      961 acggcgcagc gcttctgccg acggacgata acgccccgga tcttctccgc aacgcttata
     1021 agcctcacgg gtagcagcaa tcacaggttg caacttaatg tctgccattt gggtggtggt
     1081 agtcaagtct tctgtgaaag tatttatttc tttccaaagt ccatcgcagt aagcagtatt
     1141 cttcactgct gcatatacgg ctgctccggc aaaaacaggg caggcgttct ttatttcctg
     1201 agatactttt atttcaaaca tacttctatt caagtttata tcaacttacg ttcaagtcta
     1261 ttatttatga atcatgatcc ccgacagaat ccgtccggac ttaatgccca aacgccttgc
     1321 cgagaaaaac tcgtcgtgat gaatatacgt acatatccgg gcaagctcca cctggccgga
     1381 cggcacaccg aaagcaagga tttgcatccg gttcgcttcc cacaagtcga tatgatgttt
     1441 tccggtttcc tctttcctga tagaaatacg aggcatatca aaaccattct tctgaaatgc
     1501 ttcgtacact tcctcaccca cttcaaaaga agccaatgag atactcggac cgatacaggc
     1561 aactacatct tctccacttg tgccaaactc cttttccatc cgcaacaaag tatcacgcac
     1621 gatgtatgct accgtccctc tccatccgga atgaatggca gctatggcac tatgtttctt
     1681 atcatatatc aacacaggaa cacaatccgc agtagaaata caaagacaat atcccggctc
     1741 gcgggtaatc aaagcatcca ctccgtgcag catctcctgt cgttgttgag acgaagccga
     1801 taaataagca tccccgatca gcaggcaatt cgtctcatga gtctgcacag gaatcaccag
     1861 ttcttcgggt atctgcgaca ttccttccat cagaagcgtc tgattccgcc ggaccttttc
     1921 cgcctcgtct ccactgtaag gcgtacagtt gaatgacgca taatttccct cgctgcatcc
     1981 tccctgccgg gtagttacaa aatgagaaat gttggagtat gagcttaacg actcataccc
     2041 caacattctt ttatctcttg tgattgaaat catttttctt cccaatcctc ttcttcgtat
     2101 tcgtagtcga gatcatcatc gtcgtcgtca gcgtcttcct catattcata gtcgagttct
     2161 tcatcctcgc ccatgtcctt gagttcctgc tgcagacggg tcacgtcttt cggacggtga
     2221 acaatgtctt ctatcttatt actttccttg ttcagttcct cccacagaat gtctttcaac
     2281 actgagattc ccaaaccgga aacagaagaa atgaatatat gcggaacacc ctcgggcaat
     2341 gtcggttcaa tctcgtccat cagctcctga tcgagcatat cgctcttcgt gatagccagc
     2401 acacgttgtt tgtccagcat ttcgggattg aacgtacgca actcattcag caatacttca
     2461 tactccttgc ggatatcatc gctatccgcc ggaaccatga acaacagcaa cgagttacgc
     2521 tcgatatgac gcagaaaccg cagtcccaat ccttttccct gactggctcc ctcgatgata
     2581 cccggtatgt ccgccatcac gaatgacttt ccatcgcgat aggaaacaat tcccaaattc
     2641 ggttcgagtg tcgtaaacgg gtaatcggca atcttcggtt tcgcagccga aatggcagaa
     2701 agtaacgtag actttcccgc attcgggaaa cctaccagtc ctacatctgc caacagtttc
     2761 agctccatga tcaccgtcat ttcctgcatc ggttcgcccg gctgcgcaaa acgcggagcc
     2821 tgacgggtag ccgtcttgaa atgactgttt ccctgaccgc cacgaccgcc tttcagcaag
     2881 atcacttcct gtccgtcgtc cgtcacatcg caaaggtatt ctccggtttc ggcgttatac
     2941 actaccgttc cgcagggtac ttcgatcact ttatccgcac cgtcttttcc gaaactacgg
     3001 ttcttgctgc ccgattcgcc atgacctgcc atcgcatgac ggtcatactt caagtgaagc
     3061 aatgtccagt aattacggtt accgcgcaag ataatatggc ctcctcttcc accatcgccc
     3121 ccatcgggac ctccgttagg acaatatttc tcgcgcctca tgtgcgtaga gcctcttccg
     3181 cccttgcctg agcgacagta tatctttacg taatcaacaa aattcgattc agccatattt
     3241 tttatttatt ataatttgtc taccgcttcg cagatatcag cgaagatacc atccatagta
     3301 cccagaccgt tgatgtgctg gtatttcttt tcgttcttgt accagtcgat cagcggagat
     3361 gtctgtgaat gatatacatg cagacgtttt ttgattgttt cttcgttgtc gtcggcacga
     3421 ccggagtctt tgccacgttt gatcagacgt accatcagtt catcttccgg aacttcgaga
     3481 tccaacatta cagaaacatc ctgtcctctt tccgccaaca tcttctttaa tgcttccgcc
     3541 tgtgcaattg ttcttgggaa accgtcgaaa attacacctt tgctgtcttt gaagctatcg
     3601 aatacgcttg ccagaatatc aatcatcaat tcatccggaa tcaactgccc ctggtcgatg
     3661 taacctttag cagttttgcc cagttccgtg ccgttcttga tttctgcacg caatacatct
     3721 cctgtcgaga tgtggttgat tccatacttt tctacaatac gttcgctctg cgttcctttt
     3781 cctgaacccg gagcaccgaa aattacaatg ttcaacatct ttttaaccta aaaattaatt
     3841 tgtatttgaa tttaatctac tacagtataa atatcgggat aattgcgtcc gaaaccatca
     3901 taatccaatc cgtagccaac gataaaatca ttcggtattt ccatcgctac gtattctatg
     3961 ttcagattga ccttcagctt ttccggtttc accagcaaag aggcgatatg aatcgcttcg
     4021 gggttgcgtg tgcccagtgt atccagcaga cgctgcatcg tcagtccggt atctacaata
     4081 tcttctacga tcactaccgt acgtccggca atgtcttcat tcagcccgat cacttcttta
     4141 attactccgg tggaagtcac cccctgataa gatgccaact tcacgaatga aatttcgcac
     4201 ggaatcgtaa tatgcttcag caagtcggcg gtaaacatga acgagccgtt caacacactg
     4261 aggaagagcg gattcttacc tgccaaatca cgattgattt cgttcgctac gcgaatcact
     4321 tctttttgaa tatcctgttc cttaatggaa acagtaaatt gcttgtcttt tatctgtatg
     4381 gtatccataa ccgatcattt taaaaaagtt gtcgcaaaaa tacaattttt tattctaccc
     4441 cgtgcatcat cttctgtaat ttcttcgaga gaaggaacag aatcagtgag gcaacaccgg
     4501 acataatgac gaacagcatg aagaagtcgt acatggtagc aatctgataa ccaaggattg
     4561 atttcacttt tccgtcttcg ggatagagac cgctcagcat acctgcaaat ttatttgcgg
     4621 tggcggtaga aagataccag atccccatca tcaaggaggc gaaacgtaac ggactcaact
     4681 tattaaccat agaaagcccg ataggtgaca gagcgatttc tcccattgta tgaataaaat
     4741 aaagtcctgt cagccagatc atgctcacct ttactcccgg aatagcatct ttcactccaa
     4801 aacagatgaa gagataacca agagaaagca gcaacagacc gattgcctgc ttggtagggg
     4861 aagccggttc catgtttcgc ttattcagaa agctccatat accgggcata atataggcaa
     4921 ggatcactac aaaaagcgga ttgaatgact ggaaccacga agccggcatc tcccagccga
     4981 aaatgctgcg gtcagtctgt tcggaagcga ataatgtcag agaagctcct gcctgctcgt
     5041 aagctgccca gaagaaaatg acgaagaaag ctacgatata gattacgaaa atacggctac
     5101 gttctacttt ggtcaatgaa ccatccagca gaatgagcac tggaaagaca atacaagccg
     5161 taaagatacc cacactaatc cagtcatcgc taaaggcata gctaaaaaag gctattaagg
     5221 caactgtaag ggcagtaatg atgatgatat tacgtacttt ggtacgtttg tccatcttcg
     5281 gatgtgaaat atgttcggct ttatccccct ttttttcacg tctggcatcg gggacgatac
     5341 caatcggttc accggaagga gagaaaaggt atttattctt ctgagtttca aagaggacaa
     5401 cagtgaacag cgtcatgatt ccggatgcga ggaatcccca tttaaagtcc tgcggattac
     5461 ctgtgtctcc caagaaaccg caaatcaaag gagcagcgaa agaaccgaca ttaacaccca
     5521 tatagaaaat ggtgtatgca gcatccaacc gtttatcccc cggttcatat aattgcccga
     5581 caagcgaaga aacggtaggc ttaaagcaac cgttacctaa aatcatgaat ccgagcccac
     5641 catacatcat ccagtgggca aggtctgtat tgtttagtga agaggcactc ataaacatca
     5701 ggaactgacc gactgccatc atcaccgctc cccaaaacac cgaacgacgg atgccccaat
     5761 atttatcggc aatgtatccg ccgatcaacg gagtcagata gaccagtccg gtgtagctac
     5821 cgtagataga ggctgccgct tctttatcaa aaagcaatgc ctgcgtcaga aagaggataa
     5881 agatggcacg cataccgtag taactgaaac gttctgccgt gctcgttgcg aaaattaggt
     5941 aaaggccttt cgggtgccct ttcaatgaac tcatgaatta tgtgtttagt agtttatggg
     6001 gtgcaaaggt actaaaaagt agattaaatg cctcaaaaaa gaagattctt atggaataga
     6061 aaaatacagg atggcgtgca agaagtctca gttacccacc ttattatgtt ttcaacagtg
     6121 taaataatca agtggatatt ccccttaaat gtgggtcagt cgccatttat ccaaaagtaa
     6181 attcaacatt ctcaatactg gcatagagca ttccttcttt ttttctaagc aggattttat
     6241 tttcccttgc caaccagccg atagcaatcg ctacatcctc gaacgtcaaa cctaactcat
     6301 ggcacaaggt gaacatagac tgttcgccct tttcatttaa gatgcgccat actttcccgg
     6361 catttgagcc aattcttttc ttttccatca tgcaaacttt agaagattaa acaatttata
     6421 tttataatct aaacattgtg agcacaggag aataacgtaa agcacattac tgcactacaa
     6481 agatatcatt tttttcgaaa aaagcaaata atcaaggcat tagctgttta tattgtacca
     6541 tatctactga cagctttatt ccaaacgccg aagacactca taaaggaagc agttctatag
     6601 caggccggag aaggcgtaac tatctctcaa agtatcggaa gattaaggag aaagcagtag
     6661 aatagttaca tcaaagcacc gatatcatta actgaccacg gtcgtgacaa gcattgttca
     6721 cgaccgtgat tagcattgct cacggtcgtg gcgaagtctt gtcacggccg tgagcaacta
     6781 aagaaaaagg cactttaaga gaagaatgcc tgcatcttag ccgaaaagtc tccgcatctt
     6841 atctgaagaa tgcccgtacc tttgcagaga aatatccgcc ccccaactga ggaatcacag
     6901 acagacagga caaagccacc ccaagataac ttctgatttc ccctgcattt ttcaatttgc
     6961 cactttatct aaagccgaaa accaaccgga ataaaggatt aattcagagt ttttgtgtaa
     7021 gtttgtgcgt cgaaaactaa aagaatatcg caatgaaaat atttccaagc agcagcatta
     7081 agaagttaga tgcctatacc attgaacatg aaccgattgc atccatagat ttaatggagc
     7141 atgccgcaca ggcgctgact aaagccatca ccaacagatg gaatccggaa acacctgtca
     7201 ccatctttgc cggaccgggc aataatggcg gagacgccct cgccgtcgcc cgcatgatgg
     7261 cggaaaaagg atacaagatc gaagtatatc tcttcaacac gaaaggcgaa ctttcgcccg
     7321 actgccagac caacaaagaa ctggtagaga tgatggaaga agtaactttc catgaaatca
     7381 gcacccagtt cgtacctccc acactgacat cggagcatct cgtgatcgac ggattattcg
     7441 gttccggact caacaaacca ttgagcggag gattcgctgc cgttgtgaaa tatatcaatg
     7501 cctctcccgc catggtagtc tccatcgaca tcccttccgg gctgatggga gaagaaaata
     7561 cattcaatgt aaaaagcaat attatccgtg cggatgtcac tttcagcctg caacttccta
     7621 aactggcctt cctctttgcc gaaaatacag aatttgttgg cgaatgggaa ttattggaca
     7681 tccagctgag cgaagaagga atcgaagaga ctgaaacaaa ctacgaaatg ctggaaatcg
     7741 aagaaatccg ttcgctgatc aagccacgcc agcaattcgc ccataaagga aacttcggac
     7801 atgccctgct gatagccggt tcgaaaggaa tggcaggtgc atcggtactg gccgcccgtg
     7861 cctgtctgcg ctcgggagta ggtctgctga ccgtacacgc gccgttatgc aacaacgata
     7921 ttctgcaaac gtccgccccc gaagccatgg tagaaacaga tgtcagcgaa acatgctttg
     7981 ccgtacctac cgatacggac gattatcaag ctgtcggcat cggtccggga ctcggtcgca
     8041 gcgaggaaac ggaagctgcc ttgatagaac aactggaaca ttgtcagact ccgaccgtag
     8101 tggatgccga cgcgctcaat attctggcca atcaccgaca tacgctcacc catctgccga
     8161 aaggttccat cctcacccct cacccgaaag aactggaacg tctggtcggc aaatgtcagg
     8221 actcatacga acgactgatg aaagcctgcg aactggctca cactgccaaa gtacatatca
     8281 ttctgaaggg agcttattcc gccattatca cccccgaagg caaatgttac ttcaaccaga
     8341 ccggtaatcc cggtatggca acaggaggca gcggagatgt actgacagga gtaatccttg
     8401 cactccttgc gcaaggctat cctgccgagg atgccgcaaa gatcggtact tacattcacg
     8461 gattggccgg agacatcgcc cagaaaaaac agggcatgat cggattaatc gcaagtgata
     8521 tcgtgacctg tctgccgacg gcatggcgac ttgtaagcga ataaaagtta agaacttacg
     8581 gtttattcaa taacttcatt aactttgttt ttcaaaatca gctaaaaaga accgaatatg
     8641 aaaaagttaa tcatagcaac aggactacta atggcaactt ccgcctatgc gcagaccgaa
     8701 gtgctgacag gagtgacacg aggaaaagac tacggagtag tgtacgccct ccccaaaacc
     8761 cagatagaaa tagaaataaa agcaaataaa gtcaactata agccgggtga attcagcaaa
     8821 tacgccgacc gctacctgag actgaccaac gtctctgccg aacccgaaga atactgggaa
     8881 ttgaacagcg tcaaggtgaa acctgtaggt gtaccaaaca gcgaagccac ttatttcgtc
     8941 aaactgaaag acaaaaccgt agctcctctt atggaactga ctgaagaggg tcttatcaaa
     9001 tcaatcaacg tcccctacag cagcaacaat gcaaagaatg cagcaaacaa tgccgttgct
     9061 ccccaacgaa aagccaatcc ccgcgacttc ctcacagaag aaattctgat ggcaagttct
     9121 accgccaaga tggccgaact ggtagcaaag gaaatctata atatccgcga aagtaaaaac
     9181 gcattattgc gcggacaagc agataatatg ccgtcggacg gcgcacagct caaaatcatg
     9241 ctcgacaacc tgaatcttca ggaagaggcc atgaccgaga tgttttcggg agtccgcgat
     9301 aaagaagaaa agacatttac tgtccgcctc actccggata aagaattcga gaatgaggta
     9361 gctttccgct tttcaaagaa gctgggtgta gttgccaaca acgatttggc aggcactcca
     9421 ttctacatca gtctgaaaga cctgaaaacg gtgaagattc cgcaagagga cgggaaaaag
     9481 aagaaagaga tggatggaat tgcttataac gtaccgggac aggcaatggt gacgctgacg
     9541 gacggcaaaa agaaattgta tgaaggagaa atacctgtta ctcagttcgg tatcatagaa
     9601 taccttgctc cggtattatt caacaagaac tcgaccatca aagtttactt tgatccggtg
     9661 accggtggac tactgaaagt agatagagaa gaaggcaaat aaaacctcta aaaaaacaaa
     9721 acgatgggtg gcgaaggaca tatgctcgac atgatacgtc ggctgaaaga cggcaaagaa
     9781 gcctcccgct tacgccgtga acggagaaat gacaagttag ggcgacttag aagaaacaac
     9841 gacccttatc ttctgccgga tacgactccg gaagagatgg aacgcatcat caaggattcg
     9901 gaaaagaaaa aagaaaaaga taacagctat ttcgtatggg gaacgctcat cattatgggc
     9961 gtactgatag gatgcgctgt cctcctgtgg gcaatctttt ttaatggata attatccatt
    10021 taataaatcc gtctttctgt aattgggaaa gataggtaga tacacgagac tcgtagcctg
    10081 cttcatgctg aaagtggtct gcgagttttt ctataatctc acgaaccgtc cgctgcccgt
    10141 ctatcaggtt ccatacagcc gtaccgtgtt cttccagacg cacatgaata tctttggaca
    10201 ttcctttcgg caataaataa cgactcatcc acgaacgttt aaaacgaggg aaggagagca
    10261 caatagtctc cccttcctgt tcagctttaa tatgttcgtt acgacaaggg atcacctcca
    10321 ggaggtttat tttctctttc gtagccatat cttttctctt ttatatcttt gtttcagata
    10381 gaatatatac tgtgattatt tctgaatatt tgcttcttcc agtccgtagc ctttcttctt
    10441 gttttctgct ttcagcatca aggcaacaat cagggcaagt acaccgaaca tagcaaaaat
    10501 agccatcggc aaggtataat cataagtctg tgcaccatct acaaccggac ctttgcaata
    10561 agaattcaac acccatccaa tcagcaaagg cacgcccatc aatccccagt tctgtaccca
    10621 aaagatcaac gcataagccg ttcccaactg tttctccgga ataatcttcg gaaccgaagg
    10681 ccacattgcc gaaggaacca atgagaaagc aaatcccaga ataatcatga tcaccgttgc
    10741 aaaccaccag atattcagaa taggaagagc gaacatagtg tgtacgaaaa tcagcatcac
    10801 cgacccgatc accatcagcg tggctccctt accgatacgg tcatacaatg acccgaacaa
    10861 cggtgtcagg atgatcgcgc caatcggcag caatccggga atcgttcccg caagtttcgg
    10921 atctacattg tacttctgta ccatcaaatc agccgcatac ttgatgaagg ggaatacagc
    10981 cgaatagaac aatacgcaca gtaatgcgat cagccagaat cctttgttgg taatgatata
    11041 tacgatgtct ttcatgcgga aaggttcttc cggttccagt ccttccgcat ccagtgaagc
    11101 atccagtttc ttatcataga aagtatagat gaagaatgcg atggtaccta cgcacagcat
    11161 gacgagacag aacagaatcg gagcgggaat attggtatgg aatacgccgc tctcatccgt
    11221 agacccgaag aagtctgcca aaggaacggt aagcaccatg gccaaagttg ttccaatacg
    11281 cgcggtcgcc atttccagtc ccatagcgag agccatctct ttgcctttaa accacttcac
    11341 gataatcttc gaaacggtga tacccgcaat ttcgactcct acaccgaaaa tagcatagcc
    11401 caatgcagcc aatgtgactt gcatcttgaa tccgaaaagc atcgcacctt ccgggaaagt
    11461 agtagtaata gcataatatt tcaatccaca accaaacacc atcaataaac aggcacccat
    11521 tccggtgaag cgtactccca tcttatccag aatgatacca ccaaagatga gcatcagcag
    11581 gaatacatta aaccagccat aagcactggt gaaaaaaccg taatctaaac tgtcccagag
    11641 aagttctttt tcaagcatgg gtttcagagg agacataacg tctgtgagga agtagccgca
    11701 caacatggta aaagcgacta atgctagaac actccaacgc agcactgcgg agtcattcag
    11761 cttttgtttc aattgttctg tcattgtaat atttaaaagg agttaataat ctcgtaacgg
    11821 gcaacaaagt taactaatta tcatttgttt tactaaaaaa ggagaacatt ttataagaaa
    11881 aaggacatct gaccggatat tcctgtatga agaagagcag accggaccca ataataaaga
    11941 taggcgcgaa ccacacgtat tacacaattc tattagaatc tcttgtaatt cgcgtaattc
    12001 gcgcctataa tgaagagaac gggtcaaaaa gcccgttcac tcaataagtt taaaccgaat
    12061 atcctgtcac tgaattattc tgctgcagga gcaggagttt cagtagccgg agcttctgtt
    12121 gctggtgcag actctgcagg agcagtagcg tctgtctgag gagcagcagt accggtaggc
    12181 atattatacg gattggtttg ttgttctttc tgtgcttgtt ccaacaatac atctttagct
    12241 gcagaagaag aaggaacaac gtaagcagta gcaacgctca tcacaaccat gaagatagcc
    12301 agaccccaag ttgctttttc cagaaaatct gtagtcttgc gcacgcccat gatagcgttt
    12361 gatgaagaaa aaccagaagc aagtccgcct ccttttgaat tctgaatcag cacgatgaag
    12421 cacatcagca aggctgcaat caccattaag ataatgaata ataagtacat ttttagttat
    12481 tttgaattag cgttaataat caatttctcc aaaaatctga tttggtctgc aaagtaagca
    12541 tttttttttg gatatttcaa gcttaatttt ttaattattt ca
//
