LOCUS       c00216_gnlPro..        15869 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OJCDILHJ_216.
ACCESSION   c00216_gnlPro..
VERSION     c00216_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 20:07:50
            Original ID  :: gnl|Prokka|OJCDILHJ_216
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 73035
            Orig. end    :: 88904
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15869
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[83035:86006]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12971
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15869
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15869
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="2"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             1443..2363
                     /locus_tag="ctg216_49"
                     /transl_table=11
                     /translation="MKKYIMIGILFAFPFCLSADEPVKAIYAKITNPDNKEITVVAHRA
                     DWRYAPENSLAAIESSIRLGADVVELDVQKTKDGQLILMHDKTLDRTTTGKGKVAEWTL
                     DSIRTLYLKNGAALKTKHRVPTLEEALWVAKGRVMVNLDKAYPIFDEIFPILEKTGTVD
                     QIIMKGSKPVADVKKDLGKYLDRIIYMPIIHLDKPGAMKQLDDFMTELHPVAFELLFVS
                     DTCQAPKQVKTKLKGKSKIWYNTLWDTMAGGHDDDKSLENPDEGYGYLIDTLGAAIIQT
                     DRTAYLLEYLQSRKKRSENGQDAYH"
     CDS             2379..3737
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 153.4; E-value: 2.6e-47)"
                     /gene_kind="transport"
                     /locus_tag="ctg216_50"
                     /sec_met_domain="MFS_1 (E-value: 2.7e-47, bitscore: 153.4,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFKLLDFYKISPPVSGGETDPERSVRFKRIRWATFLSATTGYGI
                     YYVCRLSMNVIRKPIVEDGVFTETQLGIIGSCLFFVYAVGKLTNGFLADRSNVKRFMST
                     GLLCSALINLCLGFTNSFFAFVLLWGLNGWFQSMGAASGVVSLTRWYSSKERGTFYGFW
                     SASHNLGEALTFISIALLVSWMGWRYGMIGAGVIGLLGFLMMLAFMRDTPQSQGFLLDR
                     WGTSDAHSVSGKQTEEFNKAQKAVLKNPAIWILALSSAFMYISRYAVNSWGVFYLEAQK
                     GYSTLDASFIISISSVCGIVGTVFSGIISDKFFAGSRNVPALIFGLMNVSALCLFLLVP
                     GVHFWVDALAMVLFGLGIGVLICFLGGLMAVDIAPSNASGAALGVVGIASYIGAGLQDV
                     MSGILIEGQKTVQNGVEVYDFTYINWFWIGAALLSVVFALLVWNAGEKRSEIN"
     CDS             3855..3989
                     /locus_tag="ctg216_51"
                     /transl_table=11
                     /translation="MENSLSDELFCSLKNELREVDAQISVHSKKLLELIDQKKELSSN"
     CDS             4007..4261
                     /locus_tag="ctg216_52"
                     /transl_table=11
                     /translation="MTPTVIEYRGDPKRYVSVILGAIDRGRLTYNGDANCEQTFRSLSS
                     VIDVISPKNGKALSIETLVSYEKKERAGEFSDYSEGKFE"
     CDS             4354..4695
                     /locus_tag="ctg216_53"
                     /transl_table=11
                     /translation="MRRKVIAYGQYYKDFLATLTEKEIQKVKYVLSLLGTEDRLPIKFI
                     KVIRDGLYELRISYNGNIYRIFFIFDEGQIVVLFNGFHKKTQKTPSSEIDKALKIKEEY
                     YEYKKQHAD"
     CDS             4667..4978
                     /locus_tag="ctg216_54"
                     /transl_table=11
                     /translation="MSTKNNMLTDISAELDKEFGAPGTPEREKFDEEAYAFYTGQILLD
                     ARREAKVTQSELAKRINATKSYISRIESGAINPSVGTFYRIINALGLKIEIVKPIMGI"
     CDS             complement(5094..5510)
                     /locus_tag="ctg216_55"
                     /transl_table=11
                     /translation="MLFNYTTYFLVLYYFSSSSPPKVRGVREELKLFLFYFFISTFYIS
                     LKKIRMLEILSHSSHFLPFLSPKRRREIGKTQPSFFYFSPHFQISPPIEADFRKYLLSL
                     MCKRSKESDMDNLMRKLPIGIQTFEDIRRKNILL"
     CDS             5527..5859
                     /locus_tag="ctg216_56"
                     /transl_table=11
                     /translation="MKREIIAYKGYFKEFFENLDAGTQDKILYVLMLLQTQDRIPLKFM
                     RLIEEGLYELRIEYQSNIYRIFFCFDEGRIVILFNGFQKKTEKTPKKEIDKAKILRKEY
                     YGSKNK"
     CDS             5840..6145
                     /locus_tag="ctg216_57"
                     /transl_table=11
                     /translation="MEAKTNEEFFNVSALIDERFGKEGTASRAEAEEKAYAFYTGQIIE
                     DARKKAKITQAELARRIGSDRSYISRVESGQTEPKVSTFYRIMNALGCKIEFSMIL"
     CDS             complement(6215..8329)
                     /locus_tag="ctg216_58"
                     /transl_table=11
                     /translation="MKHFTIFQDFYYAIAEMTEEEIVSTIGSFTYREKVEEIRRIFAEQ
                     GEKAANEKKKELPAIAFSASYRGRRTKVNLVKYLGHIVIDIDHLSKEELARILPIIKRC
                     NYTRIAFISPKGMGVKIIVRACHPDETLPETLQEIEDFHHAAYTRLVSFYTELCRIEID
                     TSGQDVARTCLFSYDPEIYFNPNADAFLVDQPQASYKVSNRKNLSGSKQQTPPDGPPRN
                     EDTALNAHSANASLVLTLTYYHNKSEKYIAGNRNNYLHHLSCTFNRYGIPQEEASAFIK
                     SQFTDFPADETVSLINSAYAHTDEFNTCKLNGTQKRILRIEQYISEHYETRYNEVLHIM
                     EYRRRHPDTEKPEPFRILDEMMENSIWIEINELGYPCTVKTIENLIYSDFSQSYHPIRE
                     YFELLPEWDGTDYIRILADSVQTSHQEFWAECLERYLVAMCAAATQENIVNHTVLLLCS
                     EIQNIGKTTFINNLLPPELRAYLSTGLINSNNKDDLAKITQAMLINLDEFEGMSGRELN
                     AFKDLVTRKVISFRLPYARRSQNFPHTASFAGTCNYQEVLHDTTGNRRFLCFHPNSIQF
                     ITINYAQLYAQIKYLLNKPGYQYWFTQADNERLEENNEAFIFHSPEEEMVLTHIRKPER
                     FEKVYYLTVSEIAELIRERTGYQYSIGSKIQLGKVMTKHHFESKKGNNGRRYAVFIIDI
                     EQVKSNRLYE"
     CDS             8841..9344
                     /locus_tag="ctg216_59"
                     /transl_table=11
                     /translation="MAMTVSYSVVPRKNPAKKNEPAKYYAQAQASGELDFEELCEAITS
                     RSTCTETDVRAAISGILYEVKRALKAGRIARLGDLGSLQIGLNSEGAASVKEFSGSMIK
                     GAHLIFRPGKTLAELMKILSYQQVLTRAVAQAGAGDDGGEDPDKNPGSGGDGSGDEEAP
                     DPTV"
     CDS             9405..9572
                     /locus_tag="ctg216_60"
                     /transl_table=11
                     /translation="MKEIVNRILDVIMYLIPFFGKRKRDRVVREVRYHTTCKEVCKVKT
                     TEREKEHEKD"
     CDS             9559..10008
                     /locus_tag="ctg216_61"
                     /transl_table=11
                     /translation="MRKISLIVIHCSATRVDCDFTAKDVDTAHRYRGFSCWGYHYYIRK
                     SGEIEPMRDEDTVGAHARGYNAISLGVCYEGGLDENGKAADTRTPRQKEALHRLVHELL
                     QRYPEAKVVGHRDLSPDTNYNGIVDPWERIKECPCFEVIGEFSIN"
     CDS             complement(10001..10729)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 71.7;
                     E-value: 2.5e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg216_62"
                     /sec_met_domain="Radical_SAM (E-value: 1.4e-28, bitscore:
                     92.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGITFSGGEPTFQAKTLVPLVRELKEKGIHVCLDSN
                     GGLWNEDVEELFRLTDLVLLDIKEFNPNRHQTLTGRSNEQTIRTAAWLEEQEKPFWLRY
                     VLVPGYSDFEEDIRALGEALGKYKMIQRVEILPYHTLGVHKYEAMGQEYKMKGVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(10743..12971)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg216_63"
                     /sec_met_domain="Gly_radical (E-value: 4.1e-46, bitscore:
                     148.1, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1172.9, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNNIFKDGLWSSEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERENNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTIMVKNIPVLTSDTL
                     KFEEVMDNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIEGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATDEDRIENLVTMMDGYFTKGAHHLNVNVLN
                     RDMLYDAMEHPENYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             13570..14799
                     /locus_tag="ctg216_64"
                     /transl_table=11
                     /translation="MKSTFKVLFYLKKGSEKKNGEVMIMARITIDGKLCQFSTKQSIQP
                     DNWSITAGKAKGRDAGRINALLDDIRSSLNTIYHEMQRRDNYVTAEKVKNEFLGHSESH
                     ETILSLFQKHNDDVKQLVGISKTIATYRKYEVTRRHLAEFIQSKYNVSDISIKEISPMF
                     ITDFELYLRTACKCGYNTTAKFMQFFKRIIIIARNNGILVGDPFASYKIRLEKVDRGYL
                     TEDEIKIILKKKMVSERLEHVRDLFVFSCFCGLAYSDVANLRQENIQKSFDGNLWIITK
                     RVKTNTDVNVPLLDIPKMILKKYKGKLPDGKILPVISNQKLNAYLKEIADICGIKKNLT
                     FHLARHTFATTTTLSKGVPIETVSKMLGHTNIETTQIYARITNSKIGSDMQGLDKKFVG
                     IEKIYKEVAM"
     CDS             14884..15414
                     /locus_tag="ctg216_65"
                     /transl_table=11
                     /translation="MDLQIIQNKIFEVRSCRVMLDYHLAELYQVETRALKQAVKRNIER
                     FPGDFMFVLTQEEANLLLSIGVSQNVIPPAYNFGVAMPMAFTEQGVAMLSSVLRSKVAI
                     EVNISIMRAFVLMRQMAIGYEELSRRIEELEVSTDAQFNELYQALTQLLSQSKQQKERR
                     PVGFVTYNRGKNE"
ORIGIN
        1 tttgctatag gaagtgatgg agtggagaag tggcgtactc ctttgggcaa tgtcggcacg
       61 ctggatcaag gcggtgttgt gataggactc gacggaagca ttatcgttac agtgaaacgt
      121 gctccggggg aagcaaccgg aggaatcatc tctttgtctc cgggaggagc tatccaatgg
      181 cattacggca ttgcggaaga tgtaagcggt tgtgcggcaa ttgatcaagc aggaaacata
      241 catttcggca cccagtccgg caattattat atcattaaac cggaagaatc ggatgaacaa
      301 ttgattctga aaaaagacct tgctgcgttg attagtgaaa gtgactctcc tttaaaagga
      361 gattgggaag cgggaatcgg taaaatctgg agttcgccta ccatcggacc ggatggagcg
      421 atttatatcg gagtcaccaa tacggtggac cctacaaaga gcgtgttggt agctttggaa
      481 gatgagggaa ttaccggggc cgcaacctct gcctggccga tgaaagggaa ggacagacgt
      541 cactccggag cccaatcggg agggaatgga gagaatcccg gtggagaaga aggaggacag
      601 ttgcctgtga cggggaattt gaaagcagat ttaaagagtc tgtttgaaag cacctcttat
      661 aaagtgtggc tctgcgcgca tcgtggaaat acccaaaaag ggatgaaaga ggggattccc
      721 gaaaactcgt tacctgcgat agaacactcg gtcaaagcag gagttgagat gatcgagctg
      781 gatgcacggc cgacctctga cggtgtgttg gtattgatgc acgacaacac catcgaccgg
      841 acaacaaacg gtagcggtgc ggtgggagac tttacttatc agcaattaca acaattttat
      901 ctgaaagatg catccggcaa tataactggc gaacgaatcc cgactttgga ggaagcgatg
      961 aagaaaggaa aaggaaaagt ttattataat ctggatattg tcaacaagaa tgttgcggta
     1021 aatacgatcg tcgcattgct taaaaaattg gatatggaag gttccacttt gctgtatgta
     1081 tccaacaatc gcaattatgc atttgatttg aaggcagcca acagtagttt gctgttgcac
     1141 ccgatggcga aagctaccga tgacatcaca tacttctcct catcctacac tgataatgta
     1201 caaatgatgc agctgtctac gtcagatgct atgggtggaa cgatggttaa tgagattaaa
     1261 gataaaggct ggcttctttt ctccaacatt gtcggagcga atgataccaa tatgttgtcg
     1321 gaaaactact ccggtttggt gggaatgatt aacaaacgca tcaacattgt gcaaacagac
     1381 tatgctgaag tagctgccaa atatttaaag tctaaaggat acagataata gtacatatag
     1441 atatgaagaa atatataatg ataggaatct tattcgcatt tcctttctgc ctgtcggcag
     1501 acgaaccggt gaaagccatt tatgcgaaga taacgaaccc tgacaataaa gaaatcacgg
     1561 ttgtagctca tcgggcagac tggcgttacg cacccgaaaa ttcacttgcc gctattgaaa
     1621 gttccattcg tctgggagct gacgtagtgg agctggatgt tcagaaaacc aaagacggtc
     1681 aattgatcct gatgcatgac aaaacgctgg accgaacgac taccggaaaa ggaaaggtag
     1741 ccgaatggac attggattct atccggacac tctatctgaa aaatggagcg gcactcaaaa
     1801 ccaagcatcg tgtacctact ttggaagagg ctttatgggt tgccaaaggt cgtgtgatgg
     1861 tcaatctgga taaagcatat ccgatatttg acgagatttt tcccatcctc gaaaagacgg
     1921 gaacagtgga tcagattatc atgaaaggtt ccaagcctgt ggcagacgta aagaaagact
     1981 taggtaaata tctggaccgt atcatttata tgcctatcat tcatttggat aagccgggag
     2041 caatgaagca actggatgat tttatgacgg agctgcatcc cgtagctttt gaacttctat
     2101 ttgtatcgga tacctgccag gcccccaagc aagtaaaaac gaagttgaaa ggaaaaagta
     2161 aaatctggta taatacgttg tgggatacga tggctggcgg acatgatgat gataaatcgt
     2221 tggagaatcc ggacgaagga tatggttatc tgatcgatac actcggagcg gccatcattc
     2281 agacagaccg tactgcctat ctgctggaat atttgcaatc gcgtaagaag cgtagtgaaa
     2341 acggccaaga tgcgtatcat taaaatatag acttctttat gggatttaaa ctattggatt
     2401 tttataaaat ctctcctccg gtgtccgggg gagagactga tccggaacgc tctgtccgtt
     2461 tcaagcgtat tcgttgggct acctttctgt ctgccactac cggatatggc atttattatg
     2521 tttgtcgttt gagtatgaat gtaatccgta aaccgattgt agaagacgga gtttttaccg
     2581 aaacccaact ggggattatc ggttcctgcc tttttttcgt atatgccgtc ggtaagctga
     2641 ccaatggctt tcttgctgac cgtagcaatg taaagcgttt tatgtctacc ggattattgt
     2701 gttctgctct gatcaactta tgtctgggat tcacgaattc cttctttgct tttgttctcc
     2761 tttgggggtt gaatggttgg tttcagtcga tgggggcagc atcaggagtt gtgtcgctga
     2821 ctcgttggta tagtagtaaa gagcgaggta ctttttatgg cttttggtcg gccagccaca
     2881 atttgggtga agctctgact tttatatcca tcgctttgct ggtcagttgg atgggatggc
     2941 gttatgggat gatcggtgcg ggagtgattg gtttgcttgg ttttctgatg atgcttgctt
     3001 ttatgcgtga tacgcctcaa agtcagggct ttttgctaga tcggtggggg acgtcagatg
     3061 ctcattccgt ttccggtaag caaaccgagg aattcaataa agctcagaaa gcagttttga
     3121 agaatcctgc tatttggatt cttgcattat ccagtgcttt tatgtatatc agccgttatg
     3181 cagtcaatag ctggggtgtt ttctatctgg aagcgcaaaa aggttattct actttggatg
     3241 ctagttttat tatatctatc agttctgtat gcggaattgt aggtacggtt ttctcaggta
     3301 ttatttcaga taagtttttt gctggcagtc gtaatgttcc ggctttgata ttcggattaa
     3361 tgaatgtgtc tgctctttgt ttgtttctat tggttccggg ggtacatttt tgggtggatg
     3421 ctttggcgat ggtgctcttc ggtttgggca ttggagtgct gatttgtttt ttaggaggac
     3481 tgatggctgt cgatattgct cccagcaatg cgtcgggagc cgctttggga gttgtcggta
     3541 tagcgagtta tataggagcc ggtttgcagg atgtgatgag tggcattctg atcgaaggtc
     3601 agaagacggt gcaaaatgga gtagaagttt acgattttac atatatcaat tggttttgga
     3661 ttggtgcagc cttgctttca gtagtgtttg ctttgttggt ttggaatgca ggagagaaaa
     3721 gaagtgaaat aaattgagta cattaaagta aaaatagagt cattgttttt gaaggtatta
     3781 gtcaccattt cgggaagcag gcaatagctg tgctttccgg aatggctttt ttataattaa
     3841 taaaaatcgt ttttatggaa aattcattga gtgatgaatt gttttgttca ttgaagaatg
     3901 aacttcgtga agtagatgca caaatcagtg tgcatagtaa aaaactgttg gagctgattg
     3961 accaaaaaaa agaattgtcg tccaactgat tcgggaagaa gaacaaatga cgcccactgt
     4021 tatcgaatat cggggagatc cgaaacggta tgtttctgtt attctaggtg ccattgaccg
     4081 ggggaggttg acgtataatg gagacgcgaa ttgcgaacag acgttccggt ccttgtcaag
     4141 tgtgatagat gtcataagcc ctaagaacgg gaaagcgctc agtatcgaaa cgttggtctc
     4201 gtatgagaag aaagaacgtg ccggggagtt ttcagattat tcggaaggga aattcgaata
     4261 aaatgagtac ctgagaggga atttaagccc gttagcagta taaattcgac tttaaaagtt
     4321 gtatgatatt gaaactttta ttatatttgc acaatgagaa gaaaagtaat agcatacggt
     4381 caatactaca aggattttct tgccactctg acagaaaagg aaattcaaaa agtgaaatat
     4441 gtgctttcat tgcttggaac agaagaccgt ttgcctatca aatttataaa ggttatacgt
     4501 gatggtctat atgaactacg tatatcatat aacggaaaca tttaccgtat ctttttcatt
     4561 tttgatgaag ggcaaatagt tgttttattt aatggcttcc ataagaaaac acagaaaacc
     4621 ccatcatcag aaatagataa ggcattaaaa ataaaggagg aatattatga gtacaaaaaa
     4681 caacatgctg actgatatca gcgcagaact tgataaggag ttcggagcac ctgggactcc
     4741 ggaacgtgaa aagttcgatg aagaggcata cgctttttat actggtcaaa tactgttgga
     4801 tgcacgacgg gaagcaaaag taactcagtc tgaattagca aagagaatca atgcaactaa
     4861 atcgtatatc tcacgtattg aaagcggagc tataaatcca agtgtaggaa cattctaccg
     4921 aattattaat gcattaggat tgaagattga aatcgtaaaa ccaatcatgg gtatatagtc
     4981 gaaaaaaccg aaggatatct taatccttcg gtttttcata ttttactttc ctatcacttc
     5041 gattaaccaa cgatttaagt tccggctttc tgcactaaat tccactccga tctttacaat
     5101 aagatattct tccttcgtat atcttcaaag gtttgtattc caataggaag tttacgcatc
     5161 aagttgtcca tatctgattc ttttgatctt ttgcacatca aagataacaa atatttcctg
     5221 aagtctgctt caattggtgg gctgatttga aaatgcggtg agaaatagaa aaaagacggt
     5281 tgtgtttttc cgatttcccg ccgtcttttt ggagaaagaa aaggtaaaaa gtgagaggag
     5341 tgagagagga tttctaacat tcgtattttt tttagagaaa tatagaaagt agaaataaag
     5401 aaataaaata gaaaaagttt caattcctct ctcactcctc tcacttttgg gggtgaagat
     5461 gatgaaaaat aatataaaac gaggaaatat gttgtatagt tgaacaacat ttcttatatt
     5521 tgcgttatga aaagagaaat aatagcatat aaaggatact tcaaagaatt ctttgaaaat
     5581 ttagatgctg gcacccaaga taagatattg tatgtgctaa tgttattgca gacacaagac
     5641 agaatacctt tgaaatttat gcggttgata gaagaaggac tttatgaact tcgtatcgag
     5701 taccaaagca atatatatag aatattcttt tgtttcgacg aagggcgtat tgtgattctg
     5761 tttaacggtt ttcaaaagaa aaccgaaaaa acaccaaaga aagaaattga taaagcaaag
     5821 atattaagaa aggagtatta tggaagcaaa aacaaatgag gaattcttta atgtcagtgc
     5881 attaatagat gagcgttttg gtaaggaagg aacagcttct cgtgcagagg cagaagaaaa
     5941 ggcctacgcc ttttatacag gacagattat cgaggacgca agaaaaaagg ctaaaatcac
     6001 tcaggctgaa ttagcccggc gtatcggttc tgaccgttct tatatttcaa gagtagaaag
     6061 tggtcagaca gagcctaaag tatctacttt ctatcgtata atgaatgcgt taggctgtaa
     6121 aatcgaattt tcaatgattt tgtaaaaaca ataaatgcag agtatctgtc aagatgactc
     6181 tgcatttatc tatattcaca gggctttccc gcttctattc atacagcctg tttgatttta
     6241 cctgctcgat atctataata aatacggcat atcggcgccc gttatttcct tttttagatt
     6301 caaaatggtg cttagtcatc accttcccca actgtatttt tgatccgatg gaatactgat
     6361 aaccggtacg ctcacgtatt agttccgcaa tctcactgac agtcagataa taaaccttct
     6421 cgaaacgttc cggcttgcgg atatgcgtaa gaaccatttc ttcttccggt gaatgaaaga
     6481 tgaaagcctc gttattctct tcaagccgtt cattgtccgc ttgcgtgaac cagtattggt
     6541 atcccggctt attcagcaga tatttgatct gagcatagag ctgcgcataa ttgatggtaa
     6601 taaattggat ggaattagga tgaaaacaaa ggaaacgccg gttgcctgtc gtgtcgtgaa
     6661 gcacttcctg atagttgcag gttcctgcaa aggaggccgt atgagggaaa ttttgcgaac
     6721 ggcgtgcata aggcagacgg aaactgatca ctttgcgcgt taccaaatct ttgaatgcat
     6781 tcagttcccg accgctcatc ccttcaaact cgtcgagatt gatcagcatg gcctgcgtta
     6841 ttttggctaa atcatcttta ttgttcgaat tgattagtcc ggtagagaga taagcacgca
     6901 gttcgggagg caggagatta ttgataaagg tagtctttcc tatgttctgt atctcgctgc
     6961 atagcagaag taccgtgtga ttgacaatat tctcctgagt agccgctgcg cacatcgcca
     7021 ccagataacg ttccaggcat tccgcccaaa actcctgatg actcgtctgg acactatccg
     7081 ccaggatacg gatatagtcg gttccgtccc attcgggcag taattcgaaa tattcgcgaa
     7141 tgggatgata cgactggctg aaatcggagt aaatcagatt ttcgattgtt ttgacagtgc
     7201 agggatatcc cagttcgttg atttctatcc agatactgtt ttccatcatc tcatccaaga
     7261 tgcggaaagg ctccggtttc tcggtgtcgg gatgccttct gcgatattcc atgatatgca
     7321 gcacttcgtt gtagcgtgtt tcgtagtgct cgctgatata ttgctctatc cgtaatattc
     7381 gtttctgcgt gccattcagt ttacaggtat taaattcgtc ggtatgagcg taggcgctat
     7441 tgatcaaaga gactgtctcg tctgccggaa agtctgtaaa ctggcttttg ataaaagcgg
     7501 atgcttcctc ctgcggaatg ccgtagcgat tgaaggtaca tgagagatgg tgcagataat
     7561 tgttccggtt gcccgctatg tatttttcgg acttgttgtg atagtaggtt aaagtcagca
     7621 ccagagaagc gttggcggaa tgggcgttga gcgctgtgtc ttcattcctc ggggggccgt
     7681 ccggaggagt ctgttgttta ctgccggaga gatttttacg atttgaaacc ttgtaggatg
     7741 cctgaggttg atctacaaga aaagcgtcag cgttcggatt gaaataaatc tccggatcgt
     7801 aagagaacag acaagtgcgt gccacatcct gaccggaggt gtcgatttct atccgacaga
     7861 gttcggtgta aaaagaaacg agtctggtgt aagctgcatg atggaagtct tctatttcct
     7921 gaagggtttc gggcaatgtc tcatccggat ggcatgcacg cactatgatt ttcacgccca
     7981 tccctttggg actgataaag gcgatgcggg tgtaattgca tctcttgatg atagggagga
     8041 tgcgtgccaa ttcttctttg ctgagatggt cgatgtctat cacgatgtgt cccagatatt
     8101 tgacgaggtt cactttggta cgccttcctc ggtagctggc ggagaaggcg attgccggca
     8161 attctttttt cttctcattg gcagcctttt ctccttgctc tgcaaagatg cggcgtattt
     8221 cttcgacttt ttcccggtag gtaaaactgc cgatagtgga cactatttct tcttcggtca
     8281 tctctgctat tgcgtagtag aaatcttgaa atatggtgaa atgtttcatt tttattttga
     8341 ttattgtttg tcgatgcaaa ggaacttctt tgcggaaatg tgtaaaggaa ctttgtgtaa
     8401 aatggcaata agttactacg gttcgcccaa aaagtgtatg atagttgcca cttgtttcgg
     8461 cgaaaggaga cggttgcgtg cgcggtatcc ttcctgttcg agttcgtgca ggagagggag
     8521 gttgtaaata atccaacgac gaagtatttg taaagcaact ttaaggcaga catggggatt
     8581 gtaaaggtga gccaattccg ctttggtata ggtgcggata aggaaagaat cttctttgta
     8641 attcatgatg ttttcttctt gttttatgct ataaagttac aaaaaaaatc cttgtttttc
     8701 aaaggtttga cttcgttttt attcgttggg aatcaagaaa cttcgttggg gaatatggct
     8761 tgtccggata cccttatctt tgtgctgtta acaagaaagg gatgcatcct atgtattata
     8821 aactttaaaa ttattttatt atggcaatga cagtatctta ttcagtggtg ccgcgcaaga
     8881 atcctgcaaa aaagaacgaa ccggcaaagt attatgcaca ggcgcaggcg tcgggagagt
     8941 tggactttga agagttgtgc gaagcgatca ccagtcgttc tacttgtacg gaaacggatg
     9001 tacgtgcggc tatttcgggt attctttacg aagtgaagcg tgcgttgaag gcaggaagaa
     9061 ttgcgagact gggcgatttg ggcagtttgc agataggact gaacagtgaa ggtgcggcat
     9121 cggtcaagga attttccggt tcgatgatta agggggcgca tcttattttc cgccccggta
     9181 aaacgctggc ggagttgatg aagattctga gttaccagca agtgctgact cgtgcggtgg
     9241 cgcaggcggg tgcgggcgat gacgggggag aagaccctga caagaacccc ggttccggtg
     9301 gtgatggctc cggcgatgaa gaggctccgg accctacggt ataattggca gacgggtcaa
     9361 ggtaataacg aattagaata actaccactt aatattttga taagatgaaa gaaatagtaa
     9421 accggatttt agatgtgatc atgtatctga ttcctttctt cggaaagaga aagcgggaca
     9481 gggtggtgag agaagtgcgt tatcatacta cttgtaagga ggtgtgcaaa gtgaaaacga
     9541 cggaaaggga aaaggaacat gagaaagatt agtctgattg tgatccattg ttccgccacc
     9601 cgtgtcgatt gcgactttac ggcaaaggat gtggatacgg ctcaccgtta tcgtggcttt
     9661 tcgtgctggg ggtatcatta ttatatacgc aagtcgggcg agattgagcc gatgcgggat
     9721 gaagatacgg tcggagctca tgcacgtggc tacaatgcga tcagcttagg tgtatgctat
     9781 gagggcggtc tggatgagaa tggaaaagcg gcggatacgc gtacaccccg tcagaaggag
     9841 gcgctacatc gcttggtaca cgaattgttg cagcgttatc cggaagctaa agtagtaggg
     9901 catcgggatt taagtcccga caccaactat aatgggatcg tagatccttg ggaacggatt
     9961 aaagaatgcc cttgctttga ggtcattgga gaattctcca ttaattaact accaccgtag
    10021 tgaaatactc tttgaatacc tccgcagctt tttcaagctg ttcgggggta ttttctttta
    10081 cccctttcat cttgtattcc tgtcccatcg cttcgtactt atgtacgccc agtgtatggt
    10141 aaggcagtat ttccacccgt tggatcatct tgtattttcc gagtgcttct cccagtgcgc
    10201 gtatgtcttc ttcaaaatcg ctgtatccgg gcactagcac gtagcgtagc cagaaaggtt
    10261 tctcctgttc ttccagccag gcggccgtgc ggatggtttg ctcgttgctt cttccggtga
    10321 gcgtctgatg gcggttgggg ttgaattcct ttatatccaa taacacaaga tcggtcagtc
    10381 tgaataattc ttctacgtct tcgttccaaa gtcctccgtt gctgtccaga cagacatgga
    10441 tgcctttttc tttcagttcg cggaccagcg ggacgagtgt tttcgcctga aacgtcggtt
    10501 cgcctccgga gaaagtgatt cctcctcgtt tcccgaagaa ggggcgctgg ctcattgcca
    10561 tgcggacgat ttcttccggt ggggtaggcg tgcctccctt tcctgctatc gtatccggat
    10621 tggcgcaata gaggcagcgg aagttgcatc cttgaagaaa aacgacgagc cgtaagcccg
    10681 gcccgtcgaa tgttcccata ctttcgtatg aatgtacgtt tatcatcata tagagtaata
    10741 gattacatac gttcgtggaa gctacggctg ataacttcca gttggtgttc gcggctcagc
    10801 ttcacgaagt ttacggcata gccggaaacg cggatagtca gctgcggata gttttccgga
    10861 tgctccatgg catcgtacag catatcacgg ttcagtacgt ttacgttcag gtggtgggca
    10921 cctttggtga agtaaccgtc catcatcgtt acgaggttct cgatacggtc ttcgtccgta
    10981 gcacccagtg atttcggaac gatagagaag gtgttgctga taccgtcctg tgagtcacgg
    11041 taacgaagtt tcgctacaga actcagagaa gcgatcgcac cattcttgtc gcgtccgtgc
    11101 atcggattgg cacccggagc gaaggcaaca cctttggcac gtccgtcggg agtagcaccg
    11161 gtctttttgc cgtacatcac attggaagtg atagtcagca aggagagggt aggacgggca
    11221 ttcttgtaaa ctggcaattt cttcaattct tcgctgaaga agtataccag gtctacgcca
    11281 aggtggtcta ccttgtcgtt gtcgttaccg aagcaaggga attctccttc gatgtcgaag
    11341 ccttctgtca ggccgatatc gttgcggcgg gcagttactt tcgcatattt gatggcagac
    11401 agtgagtcga gtgcgatgga aagtccggca acaccgtaag caaggtttat gcgcgggttc
    11461 gtatctacaa gagccatctg ggccttctcg tagtaatact tgtcgtgcat atagtggatg
    11521 atgttcatcg cttcgttata tacgcgggcg atttcggtca gcactttctt gtagttgtcc
    11581 attacttctt cgaacttcag cgtgtcgctg gtcagtacgg ggatgttctt caccatgatt
    11641 gtaccggtat tctcgcaacg tccaccgttg atggcaagca acagggcttt ggccaggttg
    11701 caacgggcac cgaagaactg aatctgcttg cctatttcct gatatgatac gcagcaggcg
    11761 attccgtagt cgtcggactg acgtacttcg cgcatcaggt cgtcgttttc gtactggata
    11821 gaagaagtgt cgatagaaac ctttgcacag aattctttga atccttcggg aagttccggg
    11881 ctccagagta cggtcaggtt cggttccggt gaagggccga ggttgtacaa tgtctgcagg
    11941 aaacggaagg aggtctttgt cactttggta cgtccgtcgt tgagacgtcc gcccagagat
    12001 tcggttaccc aggtcgggtc gcctgcaaag atgtcgttgt atgattgcat acgcaggtgg
    12061 cggaccatac gcagtttgat gacaaactgg tcgatcagct cttgcgcgaa cgattcggtg
    12121 atggttcctt tgctcagttc atattccaga tagatatcga ggaaggagga aacgttaccc
    12181 agtgacatgg cggcaccgtc ttgttctttg acggcggcaa ggtaagccat atatacccac
    12241 tgtacggctt cttgtgccgt gtaagcggga cggctcaggt cgagaccgta gtattcgccc
    12301 atcactttca tgtctttcag tgccttgatc tgttctgcca cttcttcgcg cagacggatg
    12361 cgggcctctg tcatcggacc ggtgaggttg tgcaaatctt ccttctttgc ttcgatcaga
    12421 cggtcgatgc cgtaaagagc catacggcgg tagtcaccga tgatacgtcc gcgtgcataa
    12481 ttatcgggaa gtccggtgag gaatcccagc gaacggaagg aacggatttc ttccgtatat
    12541 acgtcgaata ctccgtcgtt gtgcgtcttg cggtagtgag tgaaaatatc ttttacgcgg
    12601 tcgtccactt ccacgccgtt ttcgtgacag gctttgctga ctacattgat acctccgaaa
    12661 ggcttgatgg cacgtttcag aagttcgtct gtctgcaggc cgacgatcag ttcgttttcc
    12721 ttgtcgatat atccggcctt gtgggaagtg atggttgata cggtaacatt atctaatgag
    12781 cggacaccgt tgttttctct ttcttctgcc aacgcttcga ggcagcggtt ccatacggct
    12841 ttggtacgtt ctgtaggtcc ttcgaggaat gaagcatctc cgtaatacgg agtgatgtta
    12901 tgacttacga aatctctgac gttgatttcg ctgctccaaa gaccgtcttt aaagatattg
    12961 tttaattcca taaaatgata aaattagagg ttgtagttat cctattcttt agagcgcaca
    13021 aagttacaat catttttcat ataatcagca taaatatgct ctattttatg cttttcaaca
    13081 taaaatacct attaattgct atccttagga aaagattaga ttaaattttt agtgaaaact
    13141 cttgcaagtt taaaatatct tcgtaccttt gcaccgcttt taacgaaaag cacttctgac
    13201 aaggaagttt tggagaggtg gcagagtggt cgattgcggc ggtcttgaaa accgttgtac
    13261 cgcgaggtac ccggggttcg aatccctgtc tctccgctga acgtgctgga cagaaatggt
    13321 cagcaaacgg acaaaaagct acaaatcaat gatttgtggc tttttttatt gcccgaaagt
    13381 cctgcttcca agacttcaaa agtacggtaa aagacaaagt ttcgttacta aatcgttacc
    13441 tattccccgc cggacaaaaa cggtaacgat ttgtccataa atgacctgat aatgacttga
    13501 ttagtccata gtctgcataa ctcgaaaacg agaggtaaaa attaattttg caactaaaaa
    13561 aagtgagtta tgaaatcgac attcaaggtt cttttttatt tgaagaaagg ttctgaaaag
    13621 aaaaacggcg aggttatgat tatggcacgc atcaccatag acggcaaact ttgccagttc
    13681 agtacgaaac agagcatcca gcccgacaac tggagcatta ctgcgggcaa agccaaaggc
    13741 agggatgccg ggaggataaa cgcccttttg gacgacatac gttcttccct gaataccatt
    13801 taccacgaaa tgcagcggcg tgacaattac gtgaccgccg agaaagtgaa aaacgagttc
    13861 ttgggacaca gcgagagcca cgaaacaatc ctttcattgt tccaaaagca caatgacgat
    13921 gtgaagcagc ttgtaggcat atccaagacg atagcgacct accgcaagta tgaagtgacc
    13981 cgccgccacc tcgctgaatt tatccaaagc aagtacaacg tatcggacat atccataaag
    14041 gagataagcc cgatgttcat taccgatttt gagttgtatt tgcgtaccgc ctgcaagtgc
    14101 ggctacaaca ccaccgccaa gttcatgcag ttcttcaagc gtatcatcat catcgcccgt
    14161 aacaacggca tactggtggg cgaccctttc gccagctaca aaatccggct ggaaaaagtg
    14221 gacaggggtt atctgacaga ggacgagatt aaaattatcc ttaaaaagaa aatggtttcc
    14281 gaacggctgg aacacgtcag ggacttgttc gtcttttcct gtttctgcgg tctggcatac
    14341 agcgatgtcg ccaatttgcg gcaggagaat atccaaaagt cttttgacgg caacctttgg
    14401 ataatcacca agcgggtaaa gaccaacacg gacgtgaatg tccccctgct ggatattccc
    14461 aagatgattt tgaagaagta caagggcaag ttgccggacg gcaagatact tcccgtaatc
    14521 agcaatcaga agctaaacgc ctacttgaaa gagattgccg atatatgcgg tattaaaaag
    14581 aacctgacat tccaccttgc ccggcacacg ttcgccacga ccaccacgct gtcaaagggc
    14641 gtacccattg aaacggtgtc caagatgctg ggacacacaa acatagaaac tacgcaaatc
    14701 tacgcccgca tcaccaacag caagataggc agcgatatgc aggggcttga caagaagttt
    14761 gtcggcattg agaagattta caaggaagtt gccatgtaat cttgattata tggaactggt
    14821 cacaatttgt gaccagtcct tactattatt ccaacattgc taaatctcct aaaatatacg
    14881 attatggatt tgcagattat ccaaaacaag atttttgagg tcagaagttg ccgggtgatg
    14941 ctcgattatc atttggcaga actctaccaa gtggaaacac gagccttgaa gcaggcggtc
    15001 aagcgcaata tcgagcgttt tccgggtgat tttatgtttg tactcaccca agaggaagct
    15061 aacttgctgt tatccatagg ggtatcacaa aatgtgatac cccctgctta caacttcggc
    15121 gttgctatgc ctatggcttt caccgagcag ggcgtagcca tgctttcttc ggttctccgc
    15181 tccaaagtag ccatagaagt aaacatttca atcatgcggg cttttgtcct catgcgccaa
    15241 atggcaatcg gttacgagga actgtcaagg cgcatcgagg aactggaggt aagcaccgat
    15301 gcgcagttca acgaactgta ccaagccctt acccagcttt tgagccagtc gaaacaacag
    15361 aaagaacgcc gtccggtagg tttcgttacc tataaccgtg gcaagaacga ataggtaacg
    15421 atttcggtaa cgaaattcca cttaataacc tatatcccag cattgtacat tcttccacct
    15481 tgcgggcagt ctaccgacta cccgcatttt ttatatcctt ttccaactgg cacatttccc
    15541 gaaacgccag ccgtgcgtgg catggctgac tgtatttcgt gaaaagagcc gttggaaacc
    15601 cgcacaagcg tattgcaagc aagctcacaa cacccttgcc tttcccgccc gcatggagtg
    15661 ttccctaaaa gatgaaagag aacaggcact tttccccagt ttccctattt gtaaatcttc
    15721 ctcttacgca gtcccccagc cgggacagtc gttttaatca tttcaatagg caaaggtagt
    15781 tacgtgttct tcacgatttt gcaaggtcga gccgttccgg tttggcgaaa aaatcttccc
    15841 tgccttgcga ggtatttttt gcccaaaac
//
