LOCUS       gnlProkkaGHOPMKBK_3    10506 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GHOPMKBK_3.
ACCESSION   gnlProkkaGHOPMKBK_3
VERSION     gnlProkkaGHOPMKBK_3
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 18:58:31
            Original ID  :: gnl|Prokka|GHOPMKBK_3
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10506
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10506
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[155:506]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      156..506
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..10506
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10506
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(156..506)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_1"
                     /sec_met_domain="PqqD_RRE (E-value: 3.9e-11, bitscore:
                     34.4, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.4e-17, bitscore: 55.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVA"
     CDS             complement(604..1992)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 92.3; E-value: 4.1e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg3_2"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMTIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             complement(2240..2635)
                     /locus_tag="ctg3_3"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPATETPAPAAE"
     CDS             complement(2642..3415)
                     /locus_tag="ctg3_4"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSFLLEETPATEQPAEETPKLKGFELIDDFIEK
                     SESDSPLCMKPLREEMPSSPTSSDELTEEETIKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             complement(3421..3948)
                     /locus_tag="ctg3_5"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPSQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSTQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             complement(3935..5176)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 390.2; E-value:
                     2.3e-118)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg3_6"
                     /transl_table=11
                     /translation="MTRAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPMSTQARLLRVLESGEFMKVGSSKVQKTDVRVVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPAIQLTEDAKKE
                     LLAYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRLPALMGTRESKGFE
                     SEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQMGTVVTTPVVTAHQPSVPA
                     IIHTMQPTVCKDDDDIQDTEEYVEESPLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             complement(5186..6280)
                     /locus_tag="ctg3_7"
                     /transl_table=11
                     /translation="MEDNKIRIGITQGDINGVGYEVILKTFSDPTMLELCTPIIYGSPK
                     VAAYHRKALDIQTNFSIVNSATEAGYNRLSVVNCTDDEVKVEFSKPDPEAGKAALGALE
                     RAIEEYREGLIDVIVTAPINKHTIQSEEFSFPGHTEYIEERLGNGDKSLMILMKNDFRV
                     ALVTTHIPVREIATTITKELIQEKLMIFHRCLKQDFGIGAPRIAVLSLNPHAGDGGLLG
                     MEEQEVIIPAMKEMEEKGILCYGPYAADGFMGSGNYTHFDGILAMYHDQGLAPFKALAM
                     EDGVNYTAGLPVVRTSPAHGTAYDIAGKGLACEDSFRQAIYVAIDVFRNRQREKVARAN
                     PLRKQYYEKRDDSDKLKLDTVDED"
     CDS             complement(6285..7325)
                     /locus_tag="ctg3_8"
                     /transl_table=11
                     /translation="MKKYSFILCIALVAFVVASCGLKGNHTSSGRAYELLVVVDHGVWD
                     RAAGRALHDALDADMPGLPQSEPSFRIMYTSPKDYDSTLKLIRNIIIVDIQDIYTKASF
                     KYAKDVYANPQMILTIQAPNEEEFEKFVEENKKTIVDFFTRAEMNRQITFLEGKHSNFI
                     SQKVDSLFGCDIWVDAELANSKTGDDFFWASTNTGTADRNFVMYSYPYTDKDTFTKEYF
                     VHKRDSVMKANIPGFKEGVYMSTDSLLTDVRPINVQNSYTMEARGLWRMKGDFMGGPYV
                     SHTRLDEKNQRIITAEIFVYSPDKMKRNLVRQMEASLYTLKLPNEVQQKQIPLGEASKE
                     AEQTNK"
     CDS             complement(7344..8378)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_9"
                     /sec_met_domain="PF04055 (E-value: 5.4e-18, bitscore: 57.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKYPLLGMTLVELQSLTKRLGMPGFAAKQIASWLYEKKVASIDD
                     MTNLSLKHRELLKQNYEVGAEAPVDEMRSVDGTVKYLYKVGENHFVESVYIPDDDRATL
                     CVSSQVGCKMNCKFCMTGKQGYTANLTASQIMNQIHSLPERDKLTNVVMMGMGEPLDNL
                     DEVLKALELLTATYGYAWSPKRITLSTVGLRKGLQRFIEENDCHLAISLHSPLTVQRAE
                     LMPAEKAFSITEMVELLKNYDFSKQRRLSFEYIVFKGLNDSQVYAKELLKLLRGLDCRV
                     NLIRFHAIPGVDLEGADMDTMTRFRDYLTSHGLFTTIRSSRGEDIFAACGMLSTAKQEK
                     NNES"
ORIGIN
        1 ggtcaaaagg ggaacaccct ttgtggagtt aatgacttac aaaaagtaaa cggactgaaa
       61 tagcccgttt aacttcttta actgtttttt ataggcctat tatttgcata ggtcttagaa
      121 ttccgtggcc tctgtggtga aatataaatt cctatttatg cgactggtat caccagtttt
      181 ataaatccat ctttctgcat ttgagaaaga taagccgata cacgcgactc gtagccctct
      241 tcattttgaa aatggtctgc gagtttttct ataatctcac gaacattgcg ttttccatct
      301 atcagttccc atacagccgt accgtgttct tccaatttca catgaagttc tttcgacatt
      361 cctttcggca caaggaagcg ttgcatccac ggatatttaa aacggggaaa ggagagcaca
      421 attgtctccc cttccctttc tgctgtaata tgttcactgc gacagggaat gacctctaac
      481 aggttgattt tctctttggc agccatactt cttatttttt atttcagagt attcatactg
      541 ataccctttt gtttacacct tgatacaaaa ttcctttgtt actttaggta ttgaatttcc
      601 cagttacttt tggatattcg cctcttccag accgtatccc ttcttcttgt tctctgcctt
      661 caacatcaaa gccacaatca gagcaagtac accaaagaga gcaaaaatag tcatcggcaa
      721 cgtgtagtca taagtctgtg caccgtctac taccggacct ttgcaataag tattcaacac
      781 ccatccgatc aacaaaggaa cacccatcaa tccccagttc tgtacccaga aaatcaatgc
      841 gtatgcggta cccaactgtt tttccggaat aatcttcgga acagacggcc acatagctga
      901 aggcaccaac gagaaggcaa atcccaatat aatcatgatg atagtagcaa accaccatat
      961 attcagtata ggcagagcaa acatcgtatg cacaaaaata agcatcactg atccgattat
     1021 catcaatgtg gctcccttac cgatacggtc ataaagcgaa ccgaacaacg gagtcaggat
     1081 aatcgcacca atcggcaaca atccgggaat cgttcccgcc aacttcggat ctacgttata
     1141 tttctgcacc atcaagtcgg cagcatactt gataaagggg aatacagccg agtagaacaa
     1201 tacacatagt aatgcaatca accagaatcc tttattggta ataatataca caatatcttt
     1261 catacggaac ggttcttccg gttccaatcc ctctgcatcc aaagaagcat ccaacttctt
     1321 atcatagaaa gtataaagga aaaaagcaat cgtacccacg cacaacataa tcagacaaaa
     1381 caaaatcgga gcaggaatat ttgtatggaa tgtgccactc tcatccgtag atccgaaaaa
     1441 gtctgccaaa ggaactgtca ataccatcgc cagagttgtt ccgatacgtg ccgtagccat
     1501 ttcaagtccc atagccaatg ccatttcctt gcccttgaac catttcacta taatcttgga
     1561 aacagtgata ccagcaatct ccacacctac accaaagata gcatatccca atgcagccaa
     1621 cgtcacctgt gttttgaatc cgaagagcat ggcaccttcc ggaaaagtag tagaaatcgc
     1681 atagtatttc aatccacaac caaacaccat caataagcaa gcccccattc cggtgaaacg
     1741 aactcccatc ttatccaaaa tgataccacc gaagatcagc atcaatagga atacattaaa
     1801 ccacccgtaa gcacttgtga agaaaccata atcaagactg tcccatagta gttctttctc
     1861 aagcatgggt tttagaggag acattacgtc ggtgaggaaa tagccgcata gcatagtaaa
     1921 tgcgaccaat gctagaacac tccatcggag tacggcggag tcattcaatt tctgtttcaa
     1981 atgttctgtc attgttatat ttaaaaaagt agttaataat cttatacagc caacaaaggt
     2041 agttaaatct cgtttgtttc tatcacaaag agattgtttt tacaagaaaa agttaagtgc
     2101 ggattacact gaccacgcgg aacattgaaa atccgtgtaa tctgcgtaat ccgcacttaa
     2161 atatcaaaga aatgcagcat ccgtctgcac cttcccatta atggttttac cccaaagtct
     2221 tacttgacga cggagtgaat tactctgctg caggagcagg agtttcagta gccggtgccg
     2281 gagtttctgt agcaggtgca ttggtagcag gagcttcagt ttgcggcgca gccgtacctg
     2341 cgggtaagtt atacgggtta gtctgttgtt ctttctgtgc ctgttccaac actgcgtctt
     2401 tagcaacagc agagcgagga actacataag cagtagcaat gctcattaca accataaaga
     2461 tggccaggcc ccatgttgct ttttccagaa agtctgtagt cttgcgcacg cccatgatgg
     2521 cgttagatga agagaaacca gaagcaagtc cgcctccttt tgagttctga atcagcacga
     2581 tgaaacacat caacaaggct gcaataacca ttaagataac gaataataag tacattttta
     2641 gttattttga attagcgtta ataatcaatt tctccaaaaa tctgatttgg tctgcaaagt
     2701 aagcattttt ttttggatat ttcaagctta attttttaat tatttcaaga gcttttgaat
     2761 atcgttgctg tttaacatag atttttgcca aagtttccgt aaaacagctg tcatcttcct
     2821 cttcttcctt tatcgtttct tcttcggtaa gttcgtccga agaggttggc gaagatggca
     2881 tttcttctct taaaggtttc atgcagaggg gagagtcgct ctcgctcttt tctataaaat
     2941 cgtcaatcag ttcgaagcct ttgagtttgg gcgtttcttc agccggctgt tccgtggccg
     3001 gagtctcctc caaaaggaaa gaggtgtaat ccatcgaata gtcgaaactg gtccgggcag
     3061 tcacctcttc gggtactgtg gacaagaaag cgtcgatcaa tgctaatgtg cggtctacgg
     3121 acggttcgtc tttcagcacc tccgtgagag gtactccctt tttccgtgcc tgcacatcat
     3181 agcggtcacc ttcaatcaac cggaacaact gccgtctgtc tgcaatgtaa agaactgctt
     3241 tccgcagttc tccaccgaaa ctaatatcat ggagaatata cagattcttc agatacaaca
     3301 gacgaagtga ctgaaaatac ggatacctcg caagaagatt gcgcagttcg tacaaagtat
     3361 ccctattcag cgtctcggga tgctgaatcc attgttgaaa gttaacagaa gtcatttata
     3421 ttaccagttt gctacagttg cattaaaaat ttggtcggtg atctctttag acatttcagc
     3481 aatcaatccg tcctgtacgg cagtcaacaa ctgggtagag tcgtaggtac ggaacgcaga
     3541 aaactgttgt tcaaagtctt cggcatgatt ggtgttgttg acaaaacgca cattgacggt
     3601 gatagtcaac ttcgtctccg aagaataacc gtcggcagat actgcctggt tgtactgatt
     3661 gtaccctgtg atttctccgt caatctgcaa gtcggcattt tgactcggct tgagcagttg
     3721 cagacgggtc tgccggatga agatatcttt caggtcctca ttgaatttgg ttgccaacgg
     3781 agcatataca tactccgact tgatcgggaa gtcggctatc gaaatggtct ttaccttatc
     3841 ataattgata gacgatccgt taaacttata ggaaacagtg cacgcaatga ctaccaacgg
     3901 caagccgaac agtagcaaag ggcgtattat tttcttaatc caattcatat tcttttattt
     3961 ttctataaag tgtacgctcg gaaatattca agtccttggc cgcactcttc cgctttccat
     4021 gatgcctctc aagtgccttg cgtatcattt ctttctccac ttcgtccagt gacaaaggag
     4081 attcttctac atattcttcc gtgtcttgta tgtcatcgtc atccttgcaa accgtaggct
     4141 gcatggtgtg aatgatagca ggtaccgaag gttgatgcgc cgtcactacc ggagtagtaa
     4201 ccaccgttcc catttgccct acctgcccca cctgtccggc acgttccgcc atcaggttgt
     4261 gcaccatctt cttcagctcc gccacttcct ggcgcatatc gaacagaaca gaataaagaa
     4321 tctcccgttc gctctcaaag cctttactct cacgcgttcc catcagcgcg ggaagacgtt
     4381 gcgtattttg tgcaggaaga taattctgca agatagcagc agagatctcc ctgttggttt
     4441 caatgataga tatttgctcg gtgatgttct tcaactgacg aacgttgccg ggccacgggt
     4501 aagccaataa ctctttcttc gcatcctccg tcaactggat agcaggcatc cggtatttct
     4561 ctgcaaagtc tgcggaaaac ttacggaaca acaagagtac atcgtcacca cgttcacgca
     4621 aaggcggtat ctggataggc accgtattca accggtaata taaatcttca cggaaacgtc
     4681 cttctgcaat cgcttgtgtc agattgacgt tggtagctgc caccacacgc acatccgttt
     4741 tttgtacttt ggacgaacct actttcataa actcaccact ctccagtaca cggagcaaac
     4801 gtgcctgggt agacatcggc aactccccta cttcatcaag aaaaatagta ccgccgtcgg
     4861 cttcgccaaa gtaccctttc cgttcgccaa tcgcaccggt aaacgcaccc ttctcatgcc
     4921 cgaacagttc ggaatcaatc gtgccctccg gaatagcacc acagttgaca gcaatatact
     4981 gtccgtgctt cctccggcta tattgatgaa taatctgcgg aaaactttct tttccgactc
     5041 cactttctcc ggtaatcagc acagacaaat cggtaggagc tacctgaatg gcaacatcta
     5101 tggcgcgcga caatgcttca gtatttccaa taataccgaa acgctgtttc acttgttgta
     5161 tctctgctct cgtcatcact cgtttttaat cttcgtctac tgtatccagc ttcagtttat
     5221 cactatcgtc acgtttctcg taatactgtt tacgcaacgg attggcacga gccacttttt
     5281 cccgctgacg attacggaac acatcgatgg caacatagat tgcctgacgg aaagaatctt
     5341 cacaagccaa tcccttgcct gcaatatcgt atgccgttcc atgagccgga gaagtacgta
     5401 ctaccggcag gcctgccgta tagttcaccc cgtcttccat agccaaggcc ttgaacggag
     5461 ccagcccctg atcgtgatac atcgccagga taccgtcaaa atgagtataa ttgcccgaac
     5521 ccataaagcc gtcggccgca taaggaccgt agcaaaggat tcctttctct tccatttctt
     5581 tcatggcagg gataatcact tcctgctctt ccattcccaa caaaccaccg tctccggcat
     5641 gaggattgag agagagcacc gcaatacgcg gagcgccgat accgaaatcc tgtttcagac
     5701 aacgatggaa tatcatcagt ttctcctgaa tcagttcttt ggtaatcgta gtcgcgatct
     5761 ctctgacagg gatatgtgtc gtcaccaaag ccacccggaa gtcattcttc atcaaaatca
     5821 tcaatgactt atcaccattg cccagacgtt cttcgatata ttccgtatgt ccggggaagg
     5881 agaactcttc cgactgaatc gtatgtttgt tgatcggagc tgttacgata acatctatca
     5941 acccttcgcg atattcttcg atggcacgtt ccaaagcccc cagcgcagct ttaccggctt
     6001 cgggatcggg tttggaaaat tccactttca cctcatcatc cgtacagttc accacgctca
     6061 aacggttgta ccccgcttcg gtagcagagt tgacaatgct gaaattggtc tgtatatcca
     6121 gcgctttgcg atgataagcc gctactttcg gtgagccata aataatcgga gtacatagtt
     6181 ccaacatcgt agggtcggaa aatgtcttaa gaatcacctc atagcccacc ccgttaatat
     6241 ctccttgggt gatacctatc cttatcttgt tatcttccat gtttttattt attagtttgt
     6301 tccgcttcct tagatgcttc tcccaatgga atctgcttct gctgaacttc attcggaagt
     6361 ttcagtgtat acagagatgc ttccatctgg cgtaccaggt tgcgtttcat tttatcaggt
     6421 gaataaacaa atatttctgc tgtaataatt cgttggtttt tctcgtccag acgagtatga
     6481 gacacatacg gaccacccat aaagtcgccc ttcatacgcc acaggccacg tgcttccatt
     6541 gtgtagctgt tctgtacatt gatcggacgg acatcggtca gcaaactatc ggtcgacata
     6601 taaacgcctt ccttgaatcc ggggatattg gctttcatca cggagtcacg tttgtgcaca
     6661 aaatattctt tggtaaacgt atccttgtca gtgtacggat aagagtacat cacaaagtta
     6721 cggtcggcag tacctgtgtt ggtagaagcc cagaagaaat catccccggt ctttgaatta
     6781 gccagttcgg catccaccca gatgtcgcat ccgaacaaac tgtccacttt ctgcgaaatg
     6841 aaattactgt gtttcccttc caggaacgta atctgacggt tcatttccgc acgggtaaag
     6901 aagtcgacaa tcgtcttttt gttctcttcc acaaacttct cgaactcttc ttcgttcgga
     6961 gcctggatag tcaatatcat ctgcggattg gcatatacgt ccttcgcata tttgaacgag
     7021 gctttcgtat atatatcctg tatatctaca ataataatgt tacgtatcaa cttcagcgta
     7081 gaatcataat ctttcggcga agtatacata atccggaaag aaggttccga ctgcggcaaa
     7141 ccgggcatat cagcatcgag cgcatcatgt aaagcccttc cggcagcacg atcccaaaca
     7201 ccgtgatcta ctacaaccaa aagctcgtaa gcacgaccac tagaggtgtg atttcctttc
     7261 agaccacaag atgcaacgac aaaggctacc aaagcgatgc ataaaataaa agaatacttt
     7321 ttcatgatgt tcggttttat atattaactt tcattatttt tctcctgttt cgctgtcgac
     7381 agcataccgc aagcggcaaa aatatcttcg cccctggatg aacggatagt ggtgaaaagt
     7441 ccgtgtgatg tcagataatc acgaaaacgg gtcatcgtat ccatatccgc cccctcgagg
     7501 tctacccccg gtatggcatg aaaacgaatc agattcaccc tgcaatccag cccgcgaaga
     7561 agtttcagca actctttggc atagacctgc gaatcattga gccctttaaa aacaatatat
     7621 tcaaacgaaa gtcgacgttg tttactaaaa tcatagtttt ttaacagttc caccatttcg
     7681 gtgattgaaa acgccttttc cgccggcatt aattcagcac gctgaacggt cagcggagag
     7741 tgaaggctga tggcaaggtg gcagtcgttt tcttcaataa aacgctgcaa tcctttccgt
     7801 agcccgacag tagaaagcgt gatacgcttc ggactccatg cgtaaccgta ggtagcggtc
     7861 agtagttcca atgccttcaa tacctcatcc aggttatcga gcggctcgcc cattcccatc
     7921 attacgacat tagtcagttt gtcccgttcc ggcagcgaat gaatctgatt catgatctgg
     7981 ctggcggtca ggttagcggt atacccctgt ttaccggtca tacagaactt acaattcatc
     8041 ttgcaaccta cttgtgacga cacgcacaac gttgcccggt catcatccgg tatataaacc
     8101 gactctacaa aatggttctc acccacttta taaagatact tcaccgtacc atctacagag
     8161 cgcatttcat ctaccggagc ttctgctccc acctcatagt tctgcttgag caactcccgg
     8221 tgtttcaatg acaaattagt catatcatca atcgaggcta ccttcttttc gtaaagccag
     8281 gatgcaatct gcttggcagc aaagccgggc atacccagtc tttttgtcaa tgattgaagc
     8341 tctacaagag tcattcctaa aaggggatat ttagacattc ttctttctgt tgatagttta
     8401 tatctgcaaa tgtaaggaaa taaagtcgat ttccgtatag caggaatgta aaagttaaca
     8461 aaaaagggaa gtatgcctcc gttatgattc aaccacgctg atatattgaa gtagcttttg
     8521 cgccatttca gaatcctcgc cattcttttt cacttcatga ccgtacgcct cacggaaaca
     8581 agccagcgcc tcttcccgtt cattacaaaa gctgtacaaa acccctaagt tctgacaagc
     8641 cagaatcgta tcttcttcct cccatcccaa atacttcttt cgcagttcga actctctgaa
     8701 gaaagcctct ttcgccattg gataattctc caacttcaca taagcctgtg ctttgtaata
     8761 atataccaga caggaagcat tagggtcagc atcatcgtga atatccaaag acgtcgcaat
     8821 acgaatcacg ttatcatagt ctttattcat gtaatactgc tgcataatat cacatctcaa
     8881 tgcctcatat cggacagtca gttccgccag acgcggtttt tcgctgaaat acatttcatg
     8941 cagaagagac tcacggaaga ataaagtaga cgcctgctca tcgccacgtt cattcatcat
     9001 ccgtttgaat tccctgcaca gataatacaa ctgtttatga caagcgacga tctgtttttt
     9061 attatctatc tgtatagcaa tgtccaacgc ctgattcatc agcatccatg cttcatcgta
     9121 tcgtttgata taataaagac atttaccctg catacgcaaa catttagcca ctccaccgga
     9181 cagtctgcca ttcaacgact cgtgcatttc agctactttc cggaatttct cggcagcact
     9241 ctcttcctca tccttatagt aatcacaata agccagatat tcggaaagtt caatgacttc
     9301 tgcctgactc ttctcgtcag cagaagccgc atgataatca agcgccctat tcaaatagat
     9361 cgccgcttca ttgtattgct cattgtagta atatgccaaa gctagatttc gacaggtgtt
     9421 ggcaatctcc agttccggag tcggtactat gttctcctgc atcaccaatg ctttcaggaa
     9481 acagtcgcat gccgtttcgt attcttcatt acgggcatac cgacatccct cattcatctt
     9541 caataccgac ttggcaatga gtggcatggc agcaccttcc atactcttct cactcacagc
     9601 agctgccgcc ttcgtcagat ggaaagaact gctcaagaaa gtagccatat cattagcaat
     9661 gacaggaatt aaaaaagaat cgatctcatc aaagtccaat tcggcataga cttcaggcgt
     9721 aacttcagga ttgtcgttca tgatcgcctt ccagctatct tccaacagag aacgattcgt
     9781 gcgatacaga atctcgaaaa tctccacatc acaaatccaa tccttcaata tatcccattc
     9841 ttgcatctta tagcattgat aggtaatctc cactttatag cgatacgaat catggtagca
     9901 gaactgtttc atgcgatagt tataatcggc aaaagtcaac ggatgggaaa ggatctcttc
     9961 ctcatccagc agagcggaaa taatttcatg gcgactatca tctatacatt cgtcatcttg
    10021 agcgaaatag cgttcgatcg cctctaccat ttgtgtgtca ccaatgcaat atcgtcctcc
    10081 tttgttggtg agccagctgc tcatttccac tctcaactgc gaccaaagta tctgattaat
    10141 gtctgccatg ctcttcactt catcttcggt aaatccttct aaagtaagtg aaagcatcag
    10201 aagcgttctt ccaatctctt cggaaccata atcagccgac aaacgccgta gcacactgtc
    10261 atagaattgc ccaacctcat tgagccggca atatccacgc atatattcat tgagagcatc
    10321 gtactgaccg aacgaaacca gctcgttgag caatacactc aaacagcgcg gttgtttagc
    10381 cagcacccac gaagcaagaa tatcttcctg ctgtgcagac aaagccttgg agtaagtaga
    10441 caaatattgc tttgagaacg acttggcatc cgcctgtgaa aagccattca actggaaatg
    10501 agcata
//
