LOCUS       c00036_gnlPro..        14241 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GHOPMKBK_36.
ACCESSION   c00036_gnlPro..
VERSION     c00036_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 19:41:48
            Original ID  :: gnl|Prokka|GHOPMKBK_36
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 29216
            Orig. end    :: 43457
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14241
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[39216:42730]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13514
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14241
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14241
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             1767..1874
                     /locus_tag="ctg36_16"
                     /transl_table=11
                     /translation="MQKSYANRAMNDLHTLNKIFILIFELIIETNKHEL"
     CDS             1871..5989
                     /locus_tag="ctg36_17"
                     /transl_table=11
                     /translation="MKKHIASTLFLSLLSILQLTAQSHSVKRLGIEQGLSNNYVVSITQ
                     DKQGFLWFATEEGLNKFDGTRFITYYKNDLPHNNQGITGNELNRVYADSKRPIIWIATQ
                     RDGLNAYNYDEQTFTAYQHNPENPHSLITNDVTDISPSTQNDDGLWVSTYYRGIEYLNI
                     NNGQFTHYNKSTVPSLPSNQTWTVLDGGDNNLYIGHVGSGFSIFSLKDKSVKNFQNETG
                     NPASLPGNDVFCIIKDTNGNIWLGTNNGLALYNAANENFITFRNNKNDKYATLCSRILS
                     IRQLKDNRLWIASELNGIAILNLKQGMFLSPEELSIEYIQEGDDSRSLSNASARCIFQD
                     SFDNVWIGTWGGGINFISSKPPLFTTLSYSPIPNNENSLNNKVASSLCMDRQGRVWIGT
                     DGGGINVFEGEKRIAIYKKESGDIPSNFILASLQDSKGNLWFGSYQGGISYYDSRNKRF
                     RSISLTGQSNLDVRTIYEDGQHNIWVGYSGGIVVLNPLTMKIIQHYNTDNSELHSDFIR
                     SIAQDEKGRFWIGTFGDGLGIYTPDLQKIKTFTQRDGFCSNTINQIIQDKQKRMWIGTG
                     EGLVCFLSTNELNYKTYQRKDGLINTNICAITEDKKGNIWFSNNKGISCYVTDKDCFYN
                     YGHSDDVPAGSFSSGCVTQGKNGQIYFGSINGVCCFNPDITMNEQPAPAAVVTEMKILG
                     RLSNPENNDMIINLSKGQNVELSHAQNSFGVRFNVQNYSLVNQVEYVYMLKGLENSWYT
                     VNESNNVTFRNIPPGKYEFFIKARVHNQEWPEEATSLTIRINPPLWLTWWAKLIYILAS
                     ISIIYLILHAYKKKLDLESLYTLEKKNHEQEQELNQERLRFYTNITHELRTPLTLILGP
                     LEDMQKEASLPAKQAQKLSVIHQSALRLLNLINQILEFRKTETQNKKLCVSKGNIAPLI
                     YEIGLKYKELNQNTKIDFRIQIEKEEMFLFFDKEIITIVLDNLISNAIKYTEQGRVTLS
                     LHQTMRNEVAYTEIKVSDTGYGISTEALPHIFDRYYQESGKHQASGTGIGLALVKNLVT
                     LHEGEIRAESVQNEGSTFYISLLTDNIYPNALHADSTEPVQEEMSQNTELEYSQETTLD
                     TGKPILLIVEDNEEIQKYIVESFTDSFEVITANNGEEGTQQALSRIPDIVVSDIMMPVM
                     DGITLCKQLKDDVRTSHIPIILLTAKDSLQDKEEGYEVGADSYLTKPFSASLLRSRINN
                     LLDSRKKLVAQFQAQSTPGNQIDLSEKRIVIAEALSKLDNEFIEKITLLIEENLSSEKI
                     DINYLSDKMCMSGSTLYRKMKALTGLSTNEYIRKVKMENAERLLLEGKFNISEIAYKVG
                     MNSTGYFRQCFKEEFGVSPSDYLKQIKQS"
     CDS             complement(6107..7069)
                     /locus_tag="ctg36_18"
                     /transl_table=11
                     /translation="MLMLRKIVFFLVLFVGLSLFAQQDYLVSSYVRGNFYNRGRVATES
                     LRASDDLIFLNVHPNKDGTLSFENPRAFQGKGVTTWEGLIKSVRAKVKGTKTKIRLGAS
                     SGEWKAMVADEAARTAFAKNIKTVLEKNKLDGIDLDFEWAENEKEYKDYSLAIVKMREV
                     LGDQYLFSVSLHPVCYKISKEAIEAVDFISLQCYGPSPVRFSVEKYDSDIQMVLKYGIP
                     KEKLVAGVPFYGVTMDNSKKTEAYFSFVQEGLITEPAQNEVIYKGEKYVFDGQDNIRTK
                     TRYAMEQGLKGMMSWDLATDLPLDDSKSLLKAMVEELRK"
     CDS             complement(7271..8467)
                     /locus_tag="ctg36_19"
                     /transl_table=11
                     /translation="MKYVKPNQVSHLSDDEIEKLIKDYYDGVKIKDIIEIYKIDCQPSS
                     FRKILPAIETEQVCLYCNHKLQIQYLSRNYSSFNTELICPECGHEPENEYCPCNTCRER
                     AREEKRKEQQKKDEQARKIKQEKEQFIREVLYFKQKQERDIDTLSFEERVYIGAILREG
                     IDEGYNFIKPFSQFRTPIAPTPVLSKDITNMLYQNNIIKIYPETDFECFTDIDFENRNY
                     SFYSNKVYWQLNLKCAYLEKVMLIDSLINPTPKTNGYETYCLWRKIALNECLEYLLHNI
                     ETMFNITYKVGDKTNGVLNDLLNEFSVGQIYHLIYTATNKALRFKEEHCVANNHAANSI
                     IGYMQSLGERAQNDHWNLNNYNRVKECPQSLISKFFFERILRINEMGFTQKPQLIGIE"
     CDS             complement(9653..9874)
                     /locus_tag="ctg36_20"
                     /transl_table=11
                     /translation="MDQYANVSICQPVYMHGATDWHIRRMGLFIVPFRFSHRWLLFCVK
                     RVGYRRKSLYRSVRNATGSRIRICYRFQ"
     CDS             10001..10705
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_21"
                     /sec_met_domain="SucD_FumR (E-value: 1.1e-131, bitscore:
                     426.9, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSVGRKVVMSVTGIALVLFLTFHMAMNLVAIISADGYNMI
                     CEFLGANWYALVATAGLAALFVIHIIYAFWLTMQNRKARGSERYAVTDKPKTVEWASQN
                     MLVLGLIVIVGLGLHLFNFWAKMQLPELMHNMGMHADTLTLAYAANGAYHIQQTFSCPV
                     YVVLYLVWLFALWFHLTHGFWSSMQSLGWNNKVWIDRWKCISNIYSTIVVLGFALVVVV
                     FFVKTLICGGAC"
     CDS             10743..12722
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 200.6; E-value:
                     1.5e-61)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_22"
                     /sec_met_domain="FAD_binding_2 (E-value: 5.9e-62, bitscore:
                     200.6, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.3e-36,
                     bitscore: 116.1, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKIDSKIPEGPVAEKWTNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKG
                     GDYRAREANVYRLAEVSNAIIDQCVAQGVPFAREYGGTLDNRSFGGAQVSRTFYAKGQT
                     GQQLLLGAYSALSRQVNVGTVKLFTRYEMQDVVIIDGRARGIIAKNLITGELERFAAHA
                     VVIATGGYGNAYFLSTNAMGCNCTAAISCYRKGAVFANPAYVQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKKEDAIKLQKGEIKGSDIPEEDRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSEAINRLGIDVVLQRYGNLFDMYEEITDVNPGE
                     LAKEISGVKYYNPMMIYPAIHYTMGGIWVDYELQTTIKGLFAIGECNFSDHGANRLGAS
                     ALMQGLADGYFVLPYTIQNYLADQITVPRFSTDLPEFAEAEKAVQAKIDKFMSIQGKES
                     VDSIHKKLGHIMWEYVGMGRTAEGLKKGIAELKAVRKEFETNLFIPGSKEGMNVELDKA
                     IRLYDFITMGELVAYDALNRNESCGGHFREEYQTEEGEAKRDDENFFYVACWEYQGDDE
                     KAPVLIKEPLVYEAIKVQTRNYKS"
     CDS             12759..13514
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_23"
                     /sec_met_domain="Fer4_7 (E-value: 1.8e-12, bitscore: 38.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 1.3e-25, bitscore: 80.3,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 7.7e-07, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQAGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISERKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIPKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNISISNIARLNRDFIIAKLKD"
     CDS             13676..14239
                     /locus_tag="ctg36_24"
                     /transl_table=11
                     /translation="MNKLLLIWIVVLLTSCITNQENAKDTLFVNLTDATDSQSLKLSDF
                     GNTVRYVPLETNEVCLIGDNPHIALLKDKIVLSTTDQCFLFHKQTGKYICSIGHIGDDP
                     SGYSSTNYWIDDAGLFYFFRAPDQLLKYNQKGEMTGKIQIPHIPAAPGYFAFYNSTIIA
                     HCNSNIGMEPGNSLLFLNSLGEKLD"
ORIGIN
        1 atagtcagta gaaggttcgg taccatacgt tttcttagtc caatcataat cggaggcttc
       61 gtaacccaaa acagcagaga tattatggtt cttaatctgt ttcgcataat tcaattgcaa
      121 ctgcatataa cgcgcaggaa cactacgatc gatttgactt ctccaacgtc ctgcggcagg
      181 tgttccgtta taagtatctt tctccttatc atatgtatag atgtgataag catattgata
      241 accgtcaaaa cgactgttgg tgtaattgta cgagaacgta gcttttgcag tcaaaccgaa
      301 agagaaatca tactgcgcat aagcattaat attggcatta cgagtcaaat tatctttgta
      361 accggcaatg tcacgactga aagcagccgg attgtaacca ttctcatgta cattattgat
      421 atattccgga ttatcattgg cataagggct ttcgataggc tgcatcttga acatagccaa
      481 tatagccgaa taataaccgt caccacccgg caaacctacg tcttcactct tttcatactt
      541 accactaatc tgtgcaccta ttgtaaaacg gtctgttatc ttagtatcaa tattcaactg
      601 aagattggta cgctcatatt taaagtcagg catcatcgca tcttgtccag tatgagctac
      661 agaaagataa tagttggtct tttcagagcc acctgtcaca ttcgcattga tgtggtattg
      721 aggtacattt tttctcatta ccatatcata atagtcatag ctcttatatc ccggttcggt
      781 accagcttcc catttagcaa gttcctcggg actatataat ttgcttggat cttcacctct
      841 attctgtgct gcttcagcca aacctcttac atattgtcct gcatttgcca attcggggaa
      901 acgggtcaga ttctgccaac catagtatcc atttacattg atgcttacct tatcattctt
      961 tttacctttc ttggtagtta ccaaaactac accatttgat gcacgcaaac cgtaaatagc
     1021 agcagaagca tccttcaaga ctgtgatact ctcgatatcc tcgatattca gagcattaaa
     1081 cacatcgcta ccggaaacat ccgatgcctg caaccagtca cggctgttca ttccaccata
     1141 aggaataccg tcgattacaa acagggggct acccatatta cggatttcaa gattgatacc
     1201 tctacccgga cgagcatcca cagcacgtgt agacacacct gctatcttac cggataaggc
     1261 tcccgcagtg gtcgtagaaa cagaacgcgt caacgcatca gacttaacat cactgatggc
     1321 tccggtcaga cttttcttgg tttgtgtacc atagcccacc accacaactt catccaaagt
     1381 ttccatatct tcttcaagaa cgatttgaag atgtgccttt tcgcctatct tcatctcttt
     1441 agtcttataa ccgatgaacg aaattgccaa tgtggcattt ttatcatcta cattaattgt
     1501 gaagttacca tcgatatcgg taatggttcc attagaagtt cctttgacag taacattggc
     1561 accaatgata tcctctcctc tcacatcggc cacatgtcct gtaacttgtg tttgtgcaaa
     1621 tgctgcagct gacagaagca actgtacgac acacatgcat aagattctta catacctcat
     1681 aaattagaat ttaaagatta aacatttttt gttgtttttt ccgatgcaaa tatagaatat
     1741 tgatataaat gaaataagca aaaatcatgc agaagagcta tgcaaatcgt gcaatgaacg
     1801 atttacatac tctaaataaa atatttattc ttatttttga gctgataatt gaaacaaata
     1861 agcacgagtt atgaaaaaac acattgcttc tactttattt ttatccttgt tgtccattct
     1921 tcaattgaca gcccagtctc attctgtaaa acgactggga atagaacaag gattatccaa
     1981 taattatgta gtcagtatta cacaagataa acaaggcttt ttatggtttg ctacagaaga
     2041 aggacttaat aaatttgacg gcacccgctt cattacttat tataaaaatg atttgccaca
     2101 taacaatcag ggaatcaccg gcaacgaact caaccgggtg tatgctgatt ccaaacgtcc
     2161 catcatttgg atagccactc aacgagacgg actaaatgca tacaattatg acgaacaaac
     2221 atttaccgcc taccaacata acccggaaaa tccacacagc ctgattacca atgatgtaac
     2281 ggatatctct ccttccaccc aaaacgatga tggtttatgg gtcagcacct attatagagg
     2341 tatagaatat ctaaatatta ataatgggca attcacacat tataataaga gtacggtgcc
     2401 tagtctgccc tccaatcaga catggacagt attggacgga ggagacaaca atttgtatat
     2461 cggccatgtt ggaagcggat tcagtatttt ttctctcaaa gacaaaagcg taaagaattt
     2521 ccagaatgaa acgggaaatc cggcaagttt gcccggtaat gatgtgtttt gtatcataaa
     2581 agatacaaac ggtaacatct ggttaggaac aaataatgga ttggctctat ataatgctgc
     2641 taatgaaaac tttatcacat tcagaaataa taagaatgac aagtatgcta ctttatgcag
     2701 tcgcatatta tctatccggc aattaaaaga taataggctc tggattgctt cagagctcaa
     2761 tggtattgcc atattaaacc tgaaacaggg tatgtttctc tcgccagagg agctttctat
     2821 tgaatacata caggagggtg atgatagtcg aagcctctct aatgcaagcg ctcgatgtat
     2881 attccaggat tctttcgaca atgtctggat aggaacatgg ggaggaggca tcaactttat
     2941 cagtagtaaa cctcctttat ttaccacgtt aagttattcc ccgattccaa acaatgaaaa
     3001 cagcctgaac aacaaagtag ccagcagtct ttgtatggac agacaaggac gggtttggat
     3061 cggaacagat ggaggaggta ttaatgtttt tgaaggagaa aaacgtattg ccatttataa
     3121 aaaagagagt ggagatattc cttcgaattt tatattagct tctttacagg attcaaaagg
     3181 gaatttatgg ttcggttcct accaaggggg aatcagctat tatgatagcc ggaacaaaag
     3241 attccgttcc atctccctca cgggacaatc taatctagac gtacgtacga tctatgaaga
     3301 tggccaacat aacatttggg taggatatag tggaggaatt gttgtattga accctctaac
     3361 catgaagatt atccagcatt acaatacaga taacagcgaa ctgcacagtg attttatacg
     3421 ttctatagct caagatgaga aaggacgttt ttggattgga actttcggag acggacttgg
     3481 catatatacc ccggacttac agaaaatcaa gacgttcact caaagagatg gcttttgttc
     3541 taacaccatc aatcagatca tacaggataa acaaaaaaga atgtggatag gaacggggga
     3601 aggattagtt tgtttcctgt cgactaatga actgaattac aaaacttacc aacgaaaaga
     3661 tggcttaatc aataccaata tctgtgcaat aacagaagat aaaaaaggga atatctggtt
     3721 tagcaataat aaaggtatca gttgctatgt tacggataaa gactgttttt ataactatgg
     3781 ccactctgac gatgttccgg caggaagctt ctcaagtggt tgtgtaacac aaggcaagaa
     3841 tggacagatt tatttcggtt ctatcaatgg agtatgttgt ttcaatcctg acattaccat
     3901 gaatgaacaa ccggccccgg cagcggttgt cacagagatg aaaatactgg gacggttgag
     3961 taatccagaa aacaatgata tgattatcaa tctctccaag ggacaaaacg ttgaattgag
     4021 tcatgcacaa aatagcttcg gagtgaggtt caacgtccaa aactattctc tcgtcaatca
     4081 agtagagtat gtttatatgc tgaaaggact cgaaaactcg tggtacaccg tcaatgaaag
     4141 taacaatgtc actttccgca acattccccc gggaaaatat gaattcttca tcaaagcgcg
     4201 agtacataat caggaatggc cggaagaagc cacttccctg accatccgta tcaatcctcc
     4261 tctctggttg acgtggtggg caaaacttat ctacatcctg gcatctatca gtatcattta
     4321 tcttatcttg catgcttaca aaaagaagtt agatctggaa agtctttata ctttggaaaa
     4381 gaaaaaccat gagcaggaac aggaattaaa tcaggaacgc ttgcgtttct ataccaatat
     4441 cacgcatgag ctgcgtaccc ctctgacctt aatcctcggt cctctcgaag atatgcagaa
     4501 agaagcatcg cttcctgcaa aacaagccca gaaactatca gttatccatc agagtgcgct
     4561 acgattgctc aatctgatta atcagattct ggaattccga aaaacagaaa cacaaaacaa
     4621 gaaattgtgt gtcagcaaag ggaacattgc ccctctgatt tatgaaatag ggcttaaata
     4681 caaagaattg aatcaaaata ccaaaattga tttccggatt cagatagaaa aagaagaaat
     4741 gtttcttttc ttcgataaag aaatcatcac gattgttttg gacaatctga tttccaatgc
     4801 tatcaaatat acggaacaag ggcgcgtaac actaagtttg catcagacca tgcgtaatga
     4861 ggtagcgtat acggaaatta aagtcagtga tacaggatac ggaatttcta ccgaggccct
     4921 gccacatatt ttcgaccgct attatcagga aagcggtaaa catcaggcat ccggtacagg
     4981 tatcgggctg gctttagtga aaaatctcgt caccttacat gaaggggaaa tccgtgcaga
     5041 aagtgtccaa aatgagggaa gtacgttcta tatcagttta ctgacggata atatctaccc
     5101 caatgcttta catgcagatt ctacagaacc ggttcaagag gagatgagtc agaatacgga
     5161 gctggaatat tcacaagaaa cgacattaga taccggtaaa ccaatcctat tgattgtaga
     5221 agacaatgaa gaaatacaga aatatatagt tgaatccttc accgactcgt tcgaggtaat
     5281 cacggccaac aacggagaag aaggaacaca acaagccctt agccgtatcc ccgatattgt
     5341 agtcagcgac attatgatgc ctgtgatgga cggtatcact ttatgtaagc aattaaaaga
     5401 tgatgtgcgc accagccata ttcctattat tctgctgaca gccaaagatt ctctgcaaga
     5461 taaagaagaa ggatatgaag taggagccga ttcttacctg acgaaacctt tcagtgcttc
     5521 tctgttacgt agccgaatca ataatctgct cgattcaagg aaaaagttag ttgcccaatt
     5581 ccaggcgcaa tctaccccgg gaaatcaaat agatttaagt gaaaagcgta tagtaattgc
     5641 cgaagcttta agcaaattag ataatgagtt tattgaaaaa attacccttt taatcgagga
     5701 aaacctttct tcagagaaga ttgatattaa ctatctatcc gataaaatgt gcatgagcgg
     5761 ttccactctt taccggaaaa tgaaagcact tacaggactc tcgaccaacg aatatatccg
     5821 gaaagtgaaa atggagaatg cagaacgttt actgcttgaa gggaagttca atatctctga
     5881 aatagcctat aaggtaggaa tgaacagtac gggatatttc cgccaatgct ttaaggaaga
     5941 atttggtgtc tctccttcag attatctgaa gcaaattaaa caatcttgag aaaggaagat
     6001 gtatcagaag tagaatttac tttcatgttg ctctgtcatt cagaacgata atgaaaaatc
     6061 tcttctgata cctcccaata ggaaatttag cgacctgtgg gggaggtcat ttccttaatt
     6121 cttcaaccat cgctttgagc aatgatttag aatcatccag tggcaaatcc gtggctaaat
     6181 cccaactcat catgcctttc agtccttgct ccatcgcata acgggtctta gtgcggatat
     6241 tgtcctgtcc gtcaaacaca tatttctctc ccttatatat tacttcattt tgtgcaggct
     6301 ccgtaatcag tccctcttgt acaaaactga aataagcctc tgtcttcttc gaattatcca
     6361 ttgtcacacc atagaaagga acccccgcca ccagtttctc tttgggaatg ccatacttca
     6421 gtaccatctg aatatccgaa tcatatttct ctaccgaaaa acgaaccggt gaaggaccgt
     6481 aacattggag tgaaataaaa tcaacggctt caatggcttc tttactaatc ttataacaaa
     6541 caggatgcag agatacacta aatagatatt gatctcccag cacctccctc atcttcacga
     6601 tagccaggct ataatctttg tattctttct cattctccgc ccactcaaaa tcaagatcaa
     6661 tgccatccag cttattcttt tccagtacag tctttatatt ctttgcaaat gccgtacgag
     6721 cagcctcatc agccaccatc gctttccatt cgccactgga agctcccaga cgtattttcg
     6781 tttttgtacc ttttactttt gcacgaaccg atttaatcaa tccttcccaa gttgtcaccc
     6841 cttttccttg aaatgcacgc ggattttcaa atgaaagtgt tccatcttta ttaggatgaa
     6901 cattcaagaa aataaggtcg tcacttgccc gcagactttc agttgcgaca cgtccccggt
     6961 tgtagaaatt tccacgcaca taagaactca ctaaataatc ttgttgtgca aataacgata
     7021 atcctacaaa taaaacaagg aagaatacaa tttttcttag cattaacata atgattgata
     7081 attaatgaat ttagaccaca aaaatacaca taacaaacag gaatggatgt tcaataatta
     7141 ctataatact tccaaaaatc aacataaagt tttctcaata acagaaaagc aggctcatag
     7201 gctgacaaga ttctttttta gtttttacac ttctgatgct aagcatattt gttccaccat
     7261 aaagataata ttattcaata cctattaatt gtggcttttg agtaaatccc atttcgttaa
     7321 ttctcaatat ccgttcaaaa aagaatttgc tgataagtga ttgaggacac tcttttactc
     7381 tattatagtt atttaaattc caatgatcat tttgagctct ttctcctaaa ctttgcatat
     7441 acccaataat tgaattagct gcatgattgt ttgctacaca gtgttcttct ttaaatctta
     7501 gtgctttatt tgtggcagtg taaatgaggt gataaatttg cccgacagaa aattcattca
     7561 ataggtcgtt tagtacccca ttcgttttat cacctacttt gtaggtaata ttgaacatcg
     7621 tttctatgtt atgcaggaga tattctaggc attcatttaa ggctattttt cgccatagac
     7681 agtatgtttc atagccattc gttttgggag taggattaat aagtgaatct ataagcatca
     7741 ccttttctaa ataagcgcac ttaagattaa gttgccaata tactttattt gaatagaatg
     7801 aatagtttct attttcaaaa tctatatcag taaaacactc aaaatctgtc tctgggtata
     7861 tttttataat attgttttga taaagcatat ttgttatatc tttcgacagc actggagtgg
     7921 gggctatggg ggtgcgaaat tggctgaatg gcttaataaa attatatcct tcatcaattc
     7981 cttctcgcaa aatagctccg atatagactc tttcttcaaa agataatgtg tctatatctc
     8041 tttcttgttt ttgtttgaaa taaagtactt cccggataaa ctgctctttt tcttgtttta
     8101 tttttcgtgc ttgttcatct ttcttttgtt gctctttacg tttttcttcc ctcgctcttt
     8161 ccctacaggt attgcaggga caatattcat tttcgggttc atgtccacat tccggacaaa
     8221 ttaattctgt gttgaaagaa gaataattgc gggacaagta ttgaatttgt agcttatgat
     8281 tgcaatatag acacacttgt tccgtttcta tagcaggtaa tatttttcta aacgatgacg
     8341 gttgacaatc tattttatat atttctatta tatcctttat cttaacgccg tcatagtagt
     8401 cttttattag tttttctatt tcatcatcgg acagatgact tacctggttg ggttttacat
     8461 atttcatgat aattttatat ttgtcgcctt attttttatt tacggcaaag ataatgcttt
     8521 ctttaagatt acgggtgcaa aaataaaaga gaatggacga aaaatatccg gagatgcagg
     8581 aattacccga aaagtgctat aatagctacc atactctttt taaaagcctt tcaaattact
     8641 tttcaactcc ttattttctc aaagtattct caccgtgatg agaattattc cccgctgtac
     8701 ttccctgata atgtgaaaat aatcttaccg atcatgatca ataagacctt tttgtttttc
     8761 acaataaagt tgcaatattt agttataaat tcattccact atatttaaag acgaccatac
     8821 aaaggcttct accaaaacat aaatagaaga aagagttcca ttttccgcaa aaaaagccta
     8881 tctttgttcc gttaagataa taaatcacgc ataagactca tgccaggaga ttcattttgc
     8941 atacaatata ctaactgtac aggatgtcca aaaaatgttg agaatatcct tgtatataga
     9001 aacttaccta aaggagagca tatccccaag gataagtgta cgcagaattg catgcttttt
     9061 atgataaagg gcgaattact tatcaatagc gaagagcatc ccggaataac gttacgcgag
     9121 agacaaattg ttttgcaagc tattggctcc aaagtcgaaa tactggcact gacagatgtt
     9181 gaatacgttg tctactggtt caacgaactg cctttgctct gcgaagaacg gtataaggaa
     9241 atgatggaac aggcggaagc tcctttgacc tacactccac tgattatgag tgaaaggctt
     9301 taccaccttg tcactagtat gcccgaattc ctcgctgaag aaaacccttg cagcaagtat
     9361 atcgatttaa aatgcaaaga actggttttc ttgattacca acttctatcc gctgccccag
     9421 ctaggttcat tcttctatcc aatcagcact tatacggaaa gtttccacta tttcgtcata
     9481 cagaattaca gcaacgtgaa gaacgtagaa gaatttgcac atctgggagg atacacgacc
     9541 actactttcc gccgcctttt caaaaaccta tatggtatgc ccgtatatga atggatactg
     9601 gaaaagaaac gggaaggaat cctggaagac ctgcaacaca ccaaaatgcg aatcactgaa
     9661 atctgtaaca gatacggatt cgactccctg tcgcatttcg cacacttctg taaagactct
     9721 ttcggcgata ccccacgcgc tttacgcaaa aaagcagcca gcggtgagaa aatcggaaag
     9781 gtacaataaa cagtcccatc ctacgaatgt gccaatcagt tgcaccatgc atatatactg
     9841 gctggcatat tgacacattg gcgtattgat ccattattaa ggaattattt ctttaattcc
     9901 ttgctcaatc aatctatttc ccctattttt gcagtccgta agaggtgtaa aacgtcgaaa
     9961 ttttagttct aacaattaaa taatttaaat tcaatcattt atgtggttaa gtaattcatc
    10021 tgtaggaagg aaagtggtga tgagcgttac cggtatcgcc cttgtcctgt ttctaacatt
    10081 tcacatggcg atgaacttgg ttgcgatcat ctcggctgat ggttacaaca tgatttgtga
    10141 gttcctggga gcaaactggt atgcattagt ggctaccgca ggactggctg ctcttttcgt
    10201 aattcacatt atctacgcat tctggctgac aatgcagaat cgcaaagcgc gtggtagcga
    10261 acgctatgca gtgacagaca aaccgaaaac tgtagaatgg gcatctcaaa acatgttggt
    10321 gctgggtctt atcgttatcg taggtcttgg tttgcacctc ttcaacttct gggcaaaaat
    10381 gcagttgccg gaactgatgc acaacatggg catgcacgct gatacattga cattggctta
    10441 tgctgctaac ggtgcatatc acattcagca gactttctct tgtccggttt acgtagttct
    10501 ttaccttgtt tggctgtttg ctttgtggtt ccacctgact cacggtttct ggagttcaat
    10561 gcaatcactg ggatggaaca acaaagtatg gattgatcgt tggaaatgta tttctaacat
    10621 ctattctaca atcgttgtac tcggtttcgc actggtagta gtggtattct ttgtgaaaac
    10681 acttatttgt ggtggtgctt gctaaatagt aaattgtaaa tgattaaatt gtaaataata
    10741 ttatgatcaa gatagattca aaaattccag aaggcccggt ggctgagaaa tggaccaact
    10801 ataaagctca ccagaaattg gtgaaccccg ctaataaacg ccgtttggat atcatcgttg
    10861 tgggtacggg tctggcaggt gcttctgctg ctgcatccct cggtgaaatg ggtttcagag
    10921 tattcaactt ctgtattcag gactctccgc gccgtgcaca ctctatcgct gcacagggtg
    10981 gtatcaatgc tgcaaagaat tatcagaatg atggtgactc cgtttaccgt ctgttttacg
    11041 atacagtaaa aggtggtgac tatcgtgcac gtgaagccaa cgtttaccgt ctggccgaag
    11101 tatccaacgc tatcatcgac caatgcgtag cccagggtgt tccttttgca cgcgaatacg
    11161 gcggtacact ggacaaccgt tctttcggtg gtgcacaggt atcacgtacg ttctacgcta
    11221 aaggccagac cggtcagcag ctgttgctgg gtgcttactc cgcactaagc cgtcaggtaa
    11281 acgtaggtac ggtgaagctg ttcacccgtt atgaaatgca ggacgttgtg atcatcgacg
    11341 gacgtgctcg cggtatcatc gccaagaact taatcaccgg cgaactggaa cgtttcgctg
    11401 ctcacgccgt agtaatcgct accggtggtt acggtaacgc ttacttcctg tctaccaacg
    11461 ctatgggttg taactgtaca gctgctatct cttgctaccg caagggtgct gtattcgcta
    11521 accccgcata cgttcagatt cacccgactt gtatcccggt acacggtgac aagcagtcca
    11581 aactgactct gatgtccgaa tctctgcgta acgacggtcg tatctgggtt ccgaagaaga
    11641 aagaagacgc tatcaaattg cagaaaggcg aaatcaaggg aagcgatatt cctgaagaag
    11701 accgcgacta ctacctggaa cgccgttatc cggcattcgg taacctggtt ccgcgtgacg
    11761 ttgccagccg tgcagctaaa gaacgttgcg acgcaggttt cggtgtgaac aacacaggtc
    11821 tggccgtatt cctcgatttc tctgaagcta tcaaccgcct gggcatcgat gtagtgcttc
    11881 agcgttatgg taacctcttc gacatgtatg aagaaatcac tgacgttaat ccgggcgaac
    11941 tggcaaaaga aatcagtggt gtgaaatatt ataatccgat gatgatttat ccggctatcc
    12001 actacacaat gggtggtatc tgggtagact acgaactgca gactaccatc aagggtctgt
    12061 tcgctatcgg tgaatgtaac ttctccgacc acggtgcaaa ccgcctcggt gcttccgcat
    12121 tgatgcaagg tctggccgac ggttacttcg tattgcctta cactatccag aactatctgg
    12181 cagatcagat tactgttcct cgtttctcta ccgatcttcc cgaatttgcc gaagcagaaa
    12241 aggctgttca agctaagatc gacaaattca tgagcatcca gggcaaagaa tcagttgatt
    12301 ctatccacaa gaaactgggt cacatcatgt gggaatacgt aggtatggga cgtacggcag
    12361 aaggcctgaa gaaaggtatc gccgaactga aagcagtccg caaggaattc gaaaccaatc
    12421 tgtttatccc cggttctaag gaaggtatga acgtagagct cgacaaggct atccgtctgt
    12481 acgacttcat cactatgggc gagctcgttg cttacgacgc attgaaccgt aacgaaagtt
    12541 gtggtggtca cttccgtgaa gaataccaga ctgaagaagg agaagcaaaa cgtgatgacg
    12601 aaaacttctt ctacgtagct tgctgggaat atcagggtga cgatgaaaag gctcctgtat
    12661 tgatcaaaga accgctggta tacgaagcta tcaaggttca gacccgtaac tacaagagct
    12721 aatcggtgaa gttaaacatt taaaagaatt agacgaaaat ggataaaaat atatcattta
    12781 cactgaaggt atggcgtcaa gcaggcccga aggctaaagg cgcttttgaa acctaccaaa
    12841 tgaaagatat ccccggtgat acttccttcc tcgaaatgct ggatattctg aacgaacagc
    12901 tgatcagcga aagaaaagaa ccggttgtat tcgaccacga ctgccgcgaa ggtatctgcg
    12961 gtatgtgttc tctttacatc aacggacatc cgcacggtcc tgcaacaggt gctactactt
    13021 gccagattta catgcgccgt ttcaacgatg gtgacaccat cactgttgaa ccttggcgtt
    13081 cggccggttt ccctgtcatc aaggacttga tggtagaccg tactgcttat gacaagatca
    13141 tgcaggccgg tggttacgta agcgttcgta caggtgctcc gcaggatgcc aacgctatcc
    13201 tgatcccgaa gcccatcgct gacgaagcta tggatgccgc ttcttgtatc ggttgcggtg
    13261 cttgtgtagc tgcttgtaag aatggttctg ccatgttgtt cgtttctgca aaggtcagcc
    13321 agctgaactt gcttccgcaa ggtaaaccgg aagctctgcg ccgtgcgaaa gctatgttgt
    13381 ctaagatgga tgaactcgga ttcggtaact gtaccaacac ccgcgcttgc gaggctgaat
    13441 gtccgaagaa catctctatc agcaacatcg cccgcctgaa ccgcgacttc atcatcgcta
    13501 aactgaaaga ctaagcgtga gcttgatttg attaatagca taaatccccc gtcggcgttg
    13561 gctggcgggg gattttcttt ttactgacca attatttata gatagcttgt tcattatccg
    13621 ttttttattc ttttctttgt gacataaggc cagacaatca aataaattaa atacgatgaa
    13681 taaattattg ctgatatgga tagtagtctt actaacctca tgcatcacaa atcaggagaa
    13741 tgccaaggat acattatttg taaatcttac ggatgcaact gattcccaaa gcctaaagtt
    13801 atctgacttc ggaaatactg tacgttatgt acctttggaa accaacgaag tatgcctgat
    13861 aggagacaat ccccatatag cgctactgaa agataagatt gtgcttagca ctacagacca
    13921 atgtttctta ttccacaaac agaccgggaa gtatatatgc agtataggcc atatcggtga
    13981 tgatccaagt ggatatagct cgacaaatta ctggatagat gatgcaggtc ttttttactt
    14041 ctttcgcgca ccggaccagc tgctaaaata taatcagaaa ggagaaatga ccgggaaaat
    14101 tcaaattcca catatacctg ccgcacccgg ctattttgca ttttacaact ctaccattat
    14161 cgcccattgt aatagtaata taggaatgga acccggtaac tctttacttt tcctcaactc
    14221 ccttggggaa aagctggatt c
//
