LOCUS       c00069_gnlPro..        14736 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HDFGDKBP_69.
ACCESSION   c00069_gnlPro..
VERSION     c00069_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 23:34:43
            Original ID  :: gnl|Prokka|HDFGDKBP_69
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 48478
            Orig. end    :: 63214
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14736
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[58478:61451]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12973
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..14736
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14736
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="2"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             391..1314
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) fn3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg69_37"
                     /sec_met_domain="fn3 (E-value: 4e-11, bitscore: 35.0,
                     seeds: 98, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDILNFIIILSMSLLLASCGDDKDGINQPDPITGLTTEVFEESI
                     SLSWDVPNGEVKKYVIVYNPGDGLIDIVDPAITKYSIEKLKPGTDYEIDLYWVNNANVR
                     SLASTVNVTIPQKEGVIEHIYVGDLLLPNQKAIDNLQLKYTSVTGKLRIGNGTSGSDIT
                     DVSMLANITEVGTNLEVDGNSLLGNLDFLKNLKKIGGNFWLRNNPMLTSITGLKNLSEI
                     KTNLYIMGNPSLTNLNGLEGLTAVKLINIGIRSGNKSDKGNEKLTDLSALKPILTSLPT
                     VSYHCEGNAYNPSVDDILNDRGSDSK"
     CDS             1324..2175
                     /locus_tag="ctg69_38"
                     /transl_table=11
                     /translation="MKYLNILLIILPFIFSCSSDTPENDKEKIPPIIDTSIRVGTFNVD
                     VGQTATAEEIALSLKSFYLDILSLEECPILIDKNSGVEEFYSIIGKALGMEYFYIGDIS
                     SGNHWIEWGKDKTGKYAGKYKVILSKTPILQSKEFALEGKGWTHSSTIRIETKIKNKEL
                     TFYSLHIPGSAGVVEGSVMKNLVDVVLMKDTSKRIIVMGDFNDLPETNAMQYIFNSGFK
                     SVWDDVEDAEQYIDKYKYGQIDNILINKNSGMKAEIAYSIFKKDISLSDHPFLWSKIII
                     GE"
     CDS             2278..3483
                     /locus_tag="ctg69_39"
                     /transl_table=11
                     /translation="MTIPPFPKWEKGYLDIHHINTGRGNCAFLIFPDGTTMMIDAGDFD
                     GKEYAAKYAPMHAAPIFPDSSYTPGSSIINYVTNLLGKDVVIDYFLLTHFHSDHYGDVQ
                     KATGTSKNGYRITGLTEVGDVIPIKMYVDRDYPDYQFPVDLRSKNDGVDLPTFLNLLEF
                     LNYQEKHNGLKVEKFDIGSNTQFVLKKEPKSYPGFEVRNIKSNNRLWTGEGKKTTILFT
                     KEELMAKNGKYSENQMSTAIVVKYGAFKYYAGGDNSGLVDQDHAEWYDIETPMAPIIGK
                     VSAVSLNHHSNRDATNRNFLEVLDPKVVVAQSWSTDHPGAEVGQRLLSKNIGTQPRDVF
                     MTYYDDETGVAIGPWFARSLKAKQGHIVIRVYPDGEYEVYVLDARKTDLVISNRFGPYS
                     SE"
     CDS             3520..4791
                     /locus_tag="ctg69_40"
                     /transl_table=11
                     /translation="MKRFILLTILCCLVLSISAQIARDEIFEDIHRSAANHYAYPDPHF
                     TMTAPPKGYKPFYLSHYARHGSRYRVNPDDYTKPLAILREAEKDGVLTDLGKKALWLVD
                     SLARGAENRYGDLTPLGARQHRGIARRMYNNFPEVFQGAAEVDARSTTVIRCILSMTAE
                     CLQLQSLNPELRIKDEATSYDMYYMNYGNEYFKKKRQEDEVIAVKAAFRKEHLHPERLM
                     KSLFNNDNYVKWKVDAGKLMSYLFELAAITQSHDTDLDLYSLFTKEECYDLWLISNLNW
                     YIDYGPSPLTQGKMPYVEANLLENILNTADTCVVKKENSATLRFGHETCLLPLACLLEL
                     GDCAYQTTDINKLSDIWRNYRIFPKACNIQFVFYRKKGNDNILVKILLNEQEMKLPLAS
                     ELVPYYHWEEVERYYRNKLATFVH"
     CDS             4911..5045
                     /locus_tag="ctg69_41"
                     /transl_table=11
                     /translation="MENSCNDELFCSLKNELREVTAQINVHSEKLMELLDQKKESSVN"
     CDS             5054..5299
                     /locus_tag="ctg69_42"
                     /transl_table=11
                     /translation="MSHLTPVTIEYRGNPKQYVSVVLDAINRGRLTYDGIANCEQTFRA
                     LASVVDVISPKNGKTLSVETLVSYEKKKRAGEFEEK"
     CDS             5356..5688
                     /locus_tag="ctg69_43"
                     /transl_table=11
                     /translation="MKREIIAYKGYFKEFFDRLDTGTQDKILYVLMLLQTQDRIPLKFM
                     KLIEEGLYELRIEYQSNIYRIFFCFDEGRIVILFNGFQKKTEKTPKKEIEKAKILRKEY
                     YGSKNK"
     CDS             5669..5974
                     /locus_tag="ctg69_44"
                     /transl_table=11
                     /translation="MEAKTNEEFFNVSALIDERFGKEGTVTRAEAEEKAYAFYTGQIIE
                     DARKKAKITQAELARRIGSDRSYISRVESGQTEPKVSTFYRIMNALGCRIEFSMSL"
     CDS             complement(6223..8340)
                     /locus_tag="ctg69_45"
                     /transl_table=11
                     /translation="MDHFTIFQDFYRVIAEMTEEEIVSAISNGTYRETVEDVRRIFAEQ
                     GEKAANEKKIELPEITFSANYRGGRSNATLVKYLGYIVVDIDHQTQEALARILALAKKC
                     AHTRIAFISPKGMGLKIVVRVCRTDGTLPETIQEIEDFHHAAYHKIASFYAQLCGVEVD
                     TSGQDVSRTCLFSYDPDIYFNPDATAVIVEQPPMFFKSQKKKRASGKKKKTTAPDNNPL
                     TEQVALNYHSSHTSLMVTLNYYHNKSEKYVTGNRNNYLHCLACMYNRYGVPQEEAAAFI
                     KSQFTDLPADEMDALIGSAYGHNEEFDTRKLNSTQKRMLQIEQHIKENYDTRYNEVLHI
                     MEYRRRKTDTEQPEPFHILDEMMENSIWMEMNELGYSCTVKTIQNLIYSDFSITYHPIR
                     EYLDSLPEWDGTDYIGILANSVHTSHQKFWVECLERYLVGMCAAATQDDVVNHTVLLLC
                     SEIQNIGKTTFINNLLPPELRAYLSTGLINPSNKDDLAKIAQAMLINLDEFEGMSGREL
                     NIFKDLVTRKVISIRLPYARRSQNFPHTASFAGTCNYQEVLHDTTGNRRFLCFHVDSME
                     FIKINYAQLYAQIKYLLNKPGYQYWFTQSENSRIEENNEDFIFHSPEEELVLTHIRKPE
                     RFEKVHYLTVTEIAELIRERTGYQYSHGTKAQLGKVMSKHGFEFHKGKNGRRYTVFIID
                     TEQVKSNRLYE"
     CDS             complement(8428..8658)
                     /locus_tag="ctg69_46"
                     /transl_table=11
                     /translation="MYYPDQPFHIRTYKKSELAHLYNPNVCLKVALQILRRWIVYNPPL
                     LQELEQEGYRARNRLLSPRQVATIIRYLGEP"
     CDS             8852..9355
                     /locus_tag="ctg69_47"
                     /transl_table=11
                     /translation="MAMTVTYSVVPRKNPAKKDESAKYYAQAQASGELDFEELCEGITS
                     RSTCTETDVRAAISGILYEAKRALKAGRIVRLGDLGSLQIGLNSEGAVSVKEFSSSLIT
                     AAHIIFRPGKTLADITKILSYQQVTTRAVAQTGGSGNEGEDDDKGSGGGSDGGGSGEAP
                     DPAA"
     CDS             9352..9543
                     /locus_tag="ctg69_48"
                     /transl_table=11
                     /translation="MITLILDQMKEIVTKILDVIMFLVPFFGKRKRNRIVREVRFNATH
                     KEVCNVKTTEREKDDEKD"
     CDS             9530..9973
                     /locus_tag="ctg69_49"
                     /transl_table=11
                     /translation="MRKISLIVIHCSATRADRDFTAKDVDTAHRFRGFSCWGYHYYIRK
                     SGQIEPMRDEDTVGAHARGFNAISLGVCYEGGLDEDGKAADTRTSRQKESLHRLVRELL
                     QRYPDAKVVGHRDLSPDTNYNGIVDPWERIKECPCFEVKAETW"
     CDS             complement(10001..10729)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 74.2;
                     E-value: 4.3e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg69_50"
                     /sec_met_domain="Radical_SAM (E-value: 2e-29, bitscore:
                     94.9, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGVTFSGGEPTFQAKALVPLVRELKEKGIHVCIDSN
                     GGIWNEEVEELFKLTDLVLLDIKEFNPARHQALTGRSNEQTIRTAAWLEENEKPFWLRY
                     VLVPGYSDFEEDIRRLGEALGKYKMVQRVEILPYHTLGVHKYEAMEQEYKLKDVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(10745..12973)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg69_51"
                     /sec_met_domain="Gly_radical (E-value: 2.3e-46, bitscore:
                     148.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1172.7, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSTEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERANNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLRNLTGPMTEARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYMEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     NFEEVMSNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIQGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATEEDRVENLVTMMDGYFTKGAHHLNVNVLN
                     REMLYDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             13575..14672
                     /locus_tag="ctg69_52"
                     /transl_table=11
                     /translation="MKSTFKILFYLKRGAIRANGCALIMGRITVDGVGTQFSTKLEVKP
                     EEWDTKANRATGRSNANKQVNSLLEEIKASLHNIYHEMQRRDNYVTAEKVKNEFLGIAE
                     SHETLLALFAKHNADVEKLVGISKTAATLQKYKVTYNHIQSFLKDKYNVSDISLKEINL
                     MFINDFEVYLMTTCKCGANTTAKFMQFFKRIILIARNNGLLVGDPFANYKIRLKKVDRG
                     YLTDEEITKILKKKFVSERLEHVRDIFVFSCFTGLAYIDVKNLTQDNIRTSFDGNLWIM
                     TKRQKTDIKVDVPLLKIPKMILDKYKDKLPNGLLLPILSNQKMNAYLKEIGDVCGIRKT
                     LTFHLASHSVFSFFLKINSLQNIPV"
     CDS             complement(14644..14736)
                     /locus_tag="ctg69_53"
                     /transl_table=11
                     /translation="SFELLQNEVEYRFSLVSKSLPVKLGYFVSY"
ORIGIN
        1 cggatgtagt tcttatgctg gcagaagctt taaatgaaat aggatatacg ggtgacgatt
       61 caggtgaggc ctttacgctt ctgaacagta tacgttcgcg cgcaggagta tctacttatg
      121 attcagacga tttgccggat caaacaagtt tcagaaaagc cattgcggat gaaagaagat
      181 tggaactcgc ttttgaaaac cataggtggt tcgatttgat tcgtacaggt actgctgtcg
      241 aaacaatgaa taatagcagc caggagagca gtaagttcac ggtgaaagat tatcaattag
      301 tatatcctat accgcaacgc gagattaatg caaatcctgt cgttattaaa caaaatccgg
      361 aatattaata taaaaaataa aaatagagtc atgaaagata ttttaaactt catcattatt
      421 ttatcgatgt ccttattgtt agcctcatgt ggagatgata aagacgggat aaatcaacca
      481 gatccgataa cagggttgac aacggaggta tttgaagaaa gtatttcttt atcatgggat
      541 gtaccaaacg gggaagtaaa gaagtatgtc attgtatata atcccggaga cggactgatt
      601 gatatcgttg atcctgctat aactaaatat tcaattgaaa agttgaaacc gggcacggac
      661 tacgagattg atttgtattg ggtgaataat gcaaatgtac gttctcttgc aagtacggtt
      721 aatgtaacga ttccacagaa agaaggagtg atagaacata tttatgtagg cgatttgctg
      781 ctgccaaatc aaaaggcaat cgataattta cagttgaaat acacttctgt gaccggtaaa
      841 ttacgaattg gaaatgggac atcaggcagt gatattacag atgtatctat gcttgcaaac
      901 attaccgagg tgggtacaaa ccttgaggta gatggtaata gtcttctggg aaatcttgat
      961 tttctaaaaa atctaaagaa gattggcggt aatttttggt tgagaaataa tccaatgttg
     1021 acttcaataa ccggtctgaa aaatttaagt gaaataaaga cgaatcttta tattatggga
     1081 aatcccagcc ttacaaactt gaatggatta gaagggctta cggcagtgaa actaattaat
     1141 atagggataa gaagtggaaa caaatcagac aaaggtaatg aaaaattaac tgacctttcc
     1201 gcattaaaac caatattaac cagtctgcct acagtaagtt atcattgtga aggtaatgcc
     1261 tacaatccat cagtagatga tatcttaaat gatagagggt ctgattctaa ataattaata
     1321 gctatgaaat atctgaatat tttgcttata atattgcctt ttatattctc atgcagtagt
     1381 gatactccgg agaatgataa ggaaaaaatc ccccctataa tagatacttc tattcgtgtc
     1441 ggaactttta acgtggatgt agggcaaacg gcgacagcgg aagaaatagc attgagtcta
     1501 aagtcttttt atttagatat tctttcattg gaagaatgtc ccattttgat tgataagaat
     1561 tccggagttg aagagtttta ttcaataata ggtaaagctt tgggaatgga atatttttat
     1621 atcggtgata tatcctccgg aaatcattgg attgaatggg gaaaggataa aactggaaaa
     1681 tatgcaggaa aatacaaagt aatattgagt aaaactccta tattgcagtc aaaagaattt
     1741 gctttggagg gaaaaggttg gacacattca tcgactattc ggattgaaac caagattaaa
     1801 aataaggaac taacctttta tagtctgcat attccgggta gcgcaggagt agttgaaggt
     1861 tctgtcatga agaatttagt agatgttgtt ttgatgaaag atactagtaa aagaatcata
     1921 gtcatgggcg acttcaatga tttgccggaa actaatgcca tgcaatacat ctttaattca
     1981 ggctttaaga gtgtatggga tgatgtggaa gatgctgaac aatatattga taaatacaaa
     2041 tatgggcaga ttgataatat attaatcaat aagaattctg gtatgaaagc ggaaatcgca
     2101 tatagcattt ttaaaaaaga cattagtctt tcagatcatc catttctatg gagtaaaata
     2161 attattggag aataaagtac agtagtaatt tataaacaga ttgatagaac gatggatata
     2221 aagaaaatag ttaatttcat atttttactc gtttttagtt gtataatcaa ggctcaaatg
     2281 acaataccgc ctttccctaa atgggagaaa ggataccttg atattcatca catcaatacc
     2341 gggcggggga attgcgcttt tctgattttt cctgacggaa cgaccatgat gattgatgcc
     2401 ggtgattttg atggcaagga atatgccgct aagtatgcac cgatgcatgc agctccgata
     2461 tttccggata gtagttatac gcccggttcg tctatcatta attatgtgac aaatctattg
     2521 ggaaaggatg tagtgattga ctattttctt ctgacccatt ttcattccga tcattatggt
     2581 gatgttcaga aggccactgg aacttccaaa aacggatatc gtattacggg gctgacggaa
     2641 gtcggagatg tgattcctat caaaatgtat gttgataggg attatcctga ctaccaattc
     2701 cccgtggatt tacgatcaaa gaatgatgga gtagatttgc ctactttctt gaacctattg
     2761 gagttcctca actatcagga aaaacacaac ggattgaaag tcgaaaagtt cgacataggc
     2821 tctaatacgc aatttgtatt aaagaaagaa ccgaaatctt atccggggtt tgaagtcagg
     2881 aatataaaat cgaataatcg gttgtggaca ggggaaggta aaaaaacgac tattctgttt
     2941 accaaggaag aattgatggc aaaaaatggc aagtatagtg aaaaccaaat gtcgacggct
     3001 attgtggtga aatatggcgc attcaagtat tatgcgggag gggataattc tggtttggta
     3061 gaccaagacc atgcggaatg gtatgatata gaaactccta tggcacccat aataggaaag
     3121 gtgtcggcag tgtcgctcaa tcatcatagc aatcgggatg ccactaaccg gaactttctc
     3181 gaagtgctcg atcctaaagt agtagtggct caatcatgga gtaccgatca tccgggagcg
     3241 gaagtggggc aacggttgtt atcaaagaat atcggaacgc agcctaggga tgtttttatg
     3301 acttactatg atgatgaaac gggggtagct attggtcctt ggtttgcccg tagcttgaaa
     3361 gcaaaacagg ggcacattgt gataagagta tatccagacg gggaatatga agtatatgtg
     3421 ctggatgccc ggaaaacaga cttggttata tcgaacaggt ttggtcctta ctctagtgaa
     3481 taattctgtg gtatcttaaa cttattaaaa aaagaaagta tgaaacgttt tattttgttg
     3541 acaatccttt gttgccttgt gcttagtata agtgcacaga tagcaagaga tgaaatattt
     3601 gaagacatac atcgctcggc agccaaccat tatgcctatc ctgatcccca tttcacaatg
     3661 actgccccac ccaaggggta taaaccgttc tacctaagcc attatgctcg tcacggttcc
     3721 cgttatagag tgaatcctga tgattatacg aagccgttgg caattcttcg cgaagcagag
     3781 aaagacggag tacttacaga tttaggcaag aaggccctct ggcttgtaga cagccttgcg
     3841 cgcggagcag aaaatagata tggtgatttg actccattag gtgcccgtca acacagggga
     3901 attgcccgaa gaatgtacaa taactttcct gaagtgtttc agggagcggc agaggtggat
     3961 gcacgttcta caaccgttat ccgctgtata ctctctatga cggctgagtg cttgcaattg
     4021 caatctctga atccggagtt gagaatcaag gatgaggcta cttcttatga tatgtattat
     4081 atgaattatg gaaatgaata cttcaaaaag aagcgtcagg aagatgaagt gattgctgta
     4141 aaggcagctt ttcggaaaga gcatctccat cccgaacgtt tgatgaagtc tctttttaat
     4201 aacgataatt atgtaaagtg gaaagtggat gctggcaagt tgatgagtta tttgtttgaa
     4261 ctggcagcca ttacgcaaag tcacgacacg gaccttgatc tttattctct ttttaccaaa
     4321 gaagagtgtt atgatttatg gctaatcagc aatctgaatt ggtatattga ctacgggccg
     4381 tctccgctca ctcaaggtaa gatgccttat gtggaagcaa acctgcttga gaatatactg
     4441 aatactgcag atacttgcgt cgtgaaaaaa gagaatagtg ctaccctgcg cttcgggcac
     4501 gagacttgtc tacttccttt ggcttgttta ttggaattag gtgattgtgc atatcagact
     4561 actgatataa ataaattgtc agatatatgg cgtaactatc gtatctttcc aaaagcttgt
     4621 aatattcagt tcgtttttta ccgtaagaaa ggaaatgata atatcttggt gaaaatttta
     4681 ctcaatgaac aagaaatgaa acttccgctt gcaagtgagc tagtacccta ttatcattgg
     4741 gaagaggtgg aaagatatta taggaataaa ttggctactt ttgtccattg aaagaaacag
     4801 taatatacaa aaactggtct taaaaatgtt agtcaccatt ccgggaagta agtaatgatt
     4861 gcttatcttt ccggaatggc ttttttataa tcaattaaat gaaaagtttt atggaaaatt
     4921 catgtaatga tgaattgttt tgttcattga aaaatgaact tcgtgaagta accgcacaaa
     4981 tcaatgtgca tagtgaaaaa ttaatggagc tgctcgacca aaaaaaagaa tcgtcagtca
     5041 actgactcga gagatgtcgc atctcacgcc tgtcaccatt gagtatcggg gaaatccgaa
     5101 gcaatatgtc tctgttgtgc tcgatgccat caatcggggt aggttgacgt atgacggaat
     5161 agcaaattgc gaacagactt ttcgtgcgtt agcaagcgtt gtagatgtga taagccctaa
     5221 gaatgggaaa acgcttagtg tagagacgct ggtgtcttat gagaagaaaa agcgtgccgg
     5281 agaatttgag gaaaaataat ataaaataaa aagacgaatg ttgtatagtt gaacaacaat
     5341 tcatatattt gcagtatgaa aagagaaata atagcatata aaggatattt caaagagttc
     5401 tttgatcgtc tggatactgg cacccaagat aagatattat atgtgttaat gctattgcaa
     5461 acgcaggaca gaataccttt gaagtttatg aagttgatag aagaaggact ttatgaactt
     5521 cgtattgagt accagagtaa tatatataga atattctttt gtttcgatga aggacgtatt
     5581 gtgatactct ttaacggatt ccaaaagaaa acagaaaaga ccccaaagaa agaaattgaa
     5641 aaagcaaaga tattaagaaa ggagtattat ggaagcaaaa acaaatgagg aattctttaa
     5701 cgtcagcgca ttaatagatg agcgttttgg taaggaagga actgttactc gtgcggaagc
     5761 agaagaaaaa gcgtatgctt tctacaccgg gcaaattatc gaagacgcaa ggaaaaaggc
     5821 taagattact caagcagagt tagcccgacg tatcggttcc gaccgttctt atatttcaag
     5881 agtggaaagt ggtcagacag agcctaaggt ttctaccttc tatcgcatca tgaatgcgtt
     5941 aggttgtagg atcgaatttt cgatgtcttt ataagaagcg attaaaaaaa catggtggga
     6001 aatttgaaaa agttaactgt ctttttcaaa tttcccaccg tttttttgag gaagaaagag
     6061 gaagaaaaag gaaaaaggtg agggtaggtg agggtaaatt tctaacattc gtattttttt
     6121 ttagaagaaa atagaagaat agaaataaga aatataaaaa tgaaaagttg caaaagtacc
     6181 ctcaccaacc ctcacctttt tgcgtgcgaa ggagatgaaa tcttattcat atagcctgtt
     6241 tgatttcacc tgttccgtat caataatgaa tacagtgtat cttctcccgt tttttccctt
     6301 atgaaattcg aagccgtgtt tggacatcac ttttcctagt tgggctttgg ttccgtgaga
     6361 atattgatac cccgtccgtt cgcgaatcaa ttccgcaatt tcagtgaccg tcagataatg
     6421 caccttttcg aaacgttccg gtttgcggat atgtgtcaac accagttctt cttccggtga
     6481 gtggaaaatg aaatcctcgt tgttctcttc aatccgtgag ttttccgact gggtgaacca
     6541 atactgatac cccggcttgt tgagtagata cttgatttgt gcatacaact gcgcgtagtt
     6601 tattttgata aactccatcg agtcgacatg aaagcagaga aaacggcggt tacctgtggt
     6661 gtcgtgaagc acttcctggt aattgcatgt gccggcaaaa gaagccgtat gaggaaagtt
     6721 ctgcgaacgc cgcgcgtatg gcaggcggat gctgattact ttgcgggtga ctaaatcctt
     6781 gaagatattc agttcccgtc cgctcatccc ttcaaactca tccagattga taagcatcgc
     6841 ctgcgctatt ttagccagat catctttgtt gctcgggttg ataagaccgg tagaaagata
     6901 ggcgcgcaat tcgggcggca gcaggttgtt gataaacgta gtctttccga tgttctgtat
     6961 ttcgctgcaa agcaacaaaa cagtgtggtt caccacatca tcttgtgtgg cggcagcgca
     7021 cattcccacc agataacgtt ccagacattc tacccaaaat ttctggtgac tagtatgcac
     7081 gctgttggca aggataccga tataatccgt tccgtcccat tcaggcagcg agtctaaata
     7141 ctcgcgaata ggatggtagg tgatgctgaa gtcggagtag atcagattct gaatcgtctt
     7201 gacggtgcac gaatagccca gttcgttcat ctccatccaa atgctgtttt ccatcatttc
     7261 gtcgagaata tggaaaggtt ccggttgctc cgtgtccgtt ttccttctgc gatattccat
     7321 gatatgaagc acttcgttgt agcgtgtatc gtaattttct ttgatatgtt gctcaatctg
     7381 taacattcgc ttctgcgtac tattcagctt gcgggtgtcg aattcctcgt tgtgtccgta
     7441 agcactcccg atcagtgcgt ccatttcatc cgcgggaaga tcggtgaact ggctcttgat
     7501 aaaagctgcc gcctcttcct gggggacgcc gtagcgattg tacatacaag ccaggcaatg
     7561 caggtagttg ttccggttgc cggtgacgta cttttcggat ttattgtgat aatagttcag
     7621 agtcaccatt aaggaagtgt gcgaggaatg gtagttgagg gccacttgtt cggtgagggg
     7681 attgttgtct ggtgctgtcg tctttttctt tttgccggat gcccttttct tcttttgaga
     7741 cttgaagaac atcggtggct gttccacgat gacagctgtg gcatcgggat tgaaataaat
     7801 atccggatcg taagagaaca ggcaagtgcg gctaacatcc tgcccggaag tgtcgacctc
     7861 aactccgcag agctgggcat aaaaggaagc gattttgtga taagcagcat gatggaaatc
     7921 ttcaatttcc tgaattgttt cgggcaatgt cccgtctgtc cggcatacac gtaccacgat
     7981 tttcagtccc attcctttgg ggctgatgaa agcgatgcgg gtgtgggcac acttttttgc
     8041 cagtgcgagg atgcgtgcca atgcttcctg tgtctgatgg tcgatgtcta ccacgatgta
     8101 tcccagatac ttgacgagag ttgcgtttga acgtcctccc cggtagttgg ctgaaaaggt
     8161 gatttctggt agttctattt tcttttcgtt ggctgctttc tcgccttgtt ccgcgaagat
     8221 tcggcgcacg tcctccaccg tttcccggta tgtgccgttg ctgatggccg atacgatttc
     8281 ttcttctgtc atttcggcta taacgcggta aaagtcttga aagatggtaa aatgatccat
     8341 gttggtttgt tctttttaat ttgcggttgc aaagaaattt gtttgtaaaa taatagaatg
     8401 gaacttttcg tttttttgat taagttccta gggttctccc aaatagcgta tgatcgttgc
     8461 cacttgccgg ggagagagaa ggcggttgcg ggcacgatag ccttcttgtt cgagttcttg
     8521 caggagcgga gggttgtaga caatccaacg acgtagtatt tgtaaggcta ctttaaggca
     8581 tacgttgggg ttgtaaagat gagctagttc cgacttttta taagtgcgga tatgaaacgg
     8641 ctggtccgga taatacatga tgaataatgt ttggtttatg ctataaagtt actgaaaatt
     8701 aatggtttat taaaagaata acgtcattat tattcataga gtatcaggaa acttcgttgg
     8761 ggaatccgga ggatggaaaa tgtgttatct ttatgtcgtt aacaaataag gaacgcgttc
     8821 gaaatgtgtg aaatcttaaa attattttat tatggcaatg acagtaactt attcagtagt
     8881 gccgcgcaag aatcctgcca aaaaggatga gtcggcaaag tattacgcgc aggcacaggc
     8941 ttcgggagag ttggattttg aagagttgtg cgaaggaatc accagtcggt ctacctgtac
     9001 ggagacagat gtgcgtgccg ccatttcggg tattctttat gaggcgaagc gtgcgttgaa
     9061 agcgggaaga atagtccggc tgggtgattt gggcagtttg cagatcgggt tgaacagtga
     9121 aggagctgtg tcggtcaagg agttttcaag ttcgctgatt acggctgccc atattatttt
     9181 ccgtcccgga aagacgttgg cggacatcac gaagattctt agctaccagc aggtaacgac
     9241 gcgtgcggtg gctcaaacgg gcggtagcgg caatgaagga gaagacgatg acaaaggttc
     9301 cggtggtggt tcagacggtg gtggaagcgg agaagctccg gatccggcag catgataact
     9361 ttaatattgg atcaaatgaa agaaattgta actaagattt tggatgtaat tatgttcctt
     9421 gtgcctttct tcggaaaaag aaagcggaac agaattgtga gagaggtgcg cttcaatgct
     9481 acccataagg aagtgtgtaa tgtgaaaacg acggaaaggg agaaggacga tgagaaagat
     9541 tagtctgatt gtgattcact gctctgctac ccgtgctgat cgcgacttca cggcgaagga
     9601 tgtggacact gcccatcgct ttcggggctt ttcgtgttgg gggtatcatt actacattcg
     9661 caagtcggga cagatagagc cgatgaggga tgaagatacg gtgggtgctc atgcacgcgg
     9721 ttttaatgcg attagtttag gggtgtgtta tgaaggcgga ctggatgagg acggaaaggc
     9781 agcggatacg cgtacttccc gccagaaaga atctttgcat cgcctggtgc gcgaactgtt
     9841 gcagcgttat ccggatgcaa aagtggtggg acaccgtgat ttgagtcctg acaccaatta
     9901 taatggaatt gttgaccctt gggagcggat caaagagtgt ccctgtttcg aggtgaaagc
     9961 agagacatgg tgatttttat cctatttatt actgtggtgg ttaattgacc accacagtag
    10021 tgaaatactc tttaaatacc tccgcagctt tttcaagttg ttcgggggta ttttctttta
    10081 cgtctttcag cttgtattcc tgctccatcg cttcatactt atgtacgcct aatgtatgat
    10141 aaggcaggat ttccactcgt tgcaccatct tatattttcc cagagcttct cctaaacggc
    10201 ggatgtcttc ctcgaaatcg ctgtatccgg gcactaatac ataacgcagc cagaaaggtt
    10261 tctcgttttc ttccagccat gctgccgtgc ggatggtttg ctcgttactt cttccggtca
    10321 gtgcttgatg gcgtgccgga ttgaactctt taatatccag caatacaaga tccgtcagtt
    10381 tgaaaagttc ttcaacttct tcgttccaga taccgccgtt gctgtctatg catacatgta
    10441 ttcccttttc tttcagttca cgcactaaag ggactagtgc tttggcctga aacgtaggtt
    10501 ctcctccgga gaaagtgact cctccgcgtt tcccgaaaaa aggacgttgg ctcatagcca
    10561 tgcggacgat ttcttccggt ggagtaggtg tgcctccttt cccggctatt gtgtcagggt
    10621 tggcgcaata caggcagcgg aaattgcatc cttgaagaaa aacgacgagc cgtaagcccg
    10681 gcccgtcgaa tgttcccata ctttcgtatg aatgtacgtt tatcgtcata ttgagtagat
    10741 ctgattacat acgttcgtgg aagctacggc tgataacttc caattgatgt tcgcggctca
    10801 acttcacgaa gtttacggca taaccggaaa cacggatggt gagttgcgga tatttttccg
    10861 gatgttccat ggcatcgtaa agcatttcac ggttcagtac gttcacgttc aggtggtgag
    10921 cgcctttggt gaaatagcca tccatcattg tcaccagatt ttctacgcga tcctcttcag
    10981 tagctcccag tgatttgggg acgatggaga aagtgttgct gataccgtcc tgtgagtcgc
    11041 ggtaacgtaa tttcgctacg gaactcaaag aggcgatggc accgttcttg tcacgtccgt
    11101 gcatagggtt ggctcccgga gcaaaagcga cacctttggc gcgtccgtcg ggagtagcac
    11161 ctgtcttctt gccatacatc acgttggaag tgatggtgag caaagataaa gtaggacggg
    11221 catttttgta aaccggaagt ttcttcaatt cttcgctgaa gaaatagacc aggtcaacac
    11281 ccaggtggtc taccttgtcg ttgtcattac cgaagcaagg gaattcgcct tgaatatcga
    11341 aaccttctgt cagaccgatg tcgttgcggc gtgcagttac tttggcatat ttgatggccg
    11401 acagtgaatc gagggcgata gaaagtccgg ctacaccata agcaaggttg atgcgtgggt
    11461 tggtatctac aagagccatt tgggcttttt cgtagtaata cttatcatgc atataatgga
    11521 tgatgttcat cgcttcgttg taaacacggg cgatttctgt caataccttc ttgtagttgc
    11581 tcattacttc ttcgaagttc agtgtgtcgc tggttagtac ggggatattt ttcaccatta
    11641 ccgtaccggt gttttcgcaa cgtccgccgt tgatggcaag cagcagggct tttgccaggt
    11701 tgcaacgtgc gccgaagaat tggatttgtt ttccgatttc ctgataagat acgcagcatg
    11761 cgattccgta gtcgtcagac tggcgtactt cacgcatcag gtcgtcgttt tcatattgga
    11821 tggaagaagt gtcgatagat acttttgcgc agaattcttt gaatccttcc ggaagttccg
    11881 ggctccacaa tacagtcagg ttcggttccg gtgaagggcc gaggttgtag agtgtttgca
    11941 ggaagcggaa agaagtcttt gtcaccttcg tgcgtccgtc gttgaggcgt ccgcccaggg
    12001 attcggttac ccatgtcggg tcgccggcaa agatgtcgtt gtaagattgc atacgcaggt
    12061 ggcgcaccat acgcagtttg atgacaaatt ggtcgatcag ctcctgtgcg aaagattctg
    12121 tgatggttcc tttgctcaat tcatattcca tataaatgtc gaggaacgaa gagacgttac
    12181 ccagtgacat ggcagcaccg tcttgttctt ttacggcagc aaggtaagcc atgtataccc
    12241 attgtactgc ttcttgtgcg gtgtaggcag gacggctcaa gtcgagtccg tagtattcgc
    12301 ccattacctt catgtccttc aatgccttga tttgctctgc cacttcttcg cgcaggcgga
    12361 tgcgggcttc ggtcatcgga ccggtaaggt tacgcaaatc ttcttttttt gcctcaatca
    12421 atcggtcgat accatagaga gccatacggc ggtagtcgcc gatgatacgt ccgcgggcat
    12481 agttgtcagg aagtccggtg aggaatccca gagaacggaa cgaacggatt tcttcggtat
    12541 atacgtcaaa tactccgtcg ttgtgcgtct tgcggtagtg agtgaatata tcttttacgc
    12601 ggtcgtccac ttccacgccg ttttcgtggc aggctttgct taccacattg atacctccga
    12661 aaggcttgat ggcacgtttc agaagttcgt ctgtctgcag accgacgatc agttcgtttt
    12721 ctttgtcgat atatccggct ttatgagaag tgatggttga gacggtgaca ttatccagtg
    12781 agcgtactcc gttattggct ctttcttctg ccagtgcttc gaggcagcgg ttccatacag
    12841 cttttgtgcg ttcggtaggt ccttcgagga aagaagcatc tccgtaatac ggagtgatgt
    12901 tatgacttac gaaatctctg acattgattt cagtgctcca aagaccgtct ttaaagatct
    12961 tatttaattc cataaatgat aaaattagag gttgtagtta tccttttctt tagagcgcac
    13021 aaagttacaa cgttttttca tataatcagc ataaatatgc tctattttat gcttttcaac
    13081 ataaaatacc tagatattgc tattctttgg aaatgatgtt cgtgattttt ttttgtgaaa
    13141 actcttgtaa gtttaaaata tattcgtacc tttgcaccgc ttttaacgaa aagcacttct
    13201 gataaagaag ttttggagag gtggcagagt ggtcgattgc ggcggtcttg aaaaccgttg
    13261 tactgcgagg tacccggggt tcgaatccct gtctctccgc agaaacccta agacaaatag
    13321 ggtcaaaaat aggacaagtc ctacaatatc aacgtattgt aggacttttt ttattgcttc
    13381 ttgtcggggg taaaagacac aaaatagacc ctttcagaca tagttcagta accaaatcgt
    13441 aacctacaat ttcacctacc tattaggtta cgaaatgtcg caaaatggct atcttttgtc
    13501 gatgtttgtc cggtatgtat taatctcatt ttcaattaat aacagtagct ttgctgcttt
    13561 aaaaaagtga gattatgaag agtacattta aaattctctt ttatctgaaa agaggtgcta
    13621 ttagggcaaa tggttgtgcc cttatcatgg gacgtataac tgtggatggt gtgggaactc
    13681 aattcagcac caagttagag gttaaaccgg aagaatggga cacaaaggca aaccgagcaa
    13741 ccggacgtag caatgccaat aaacaagtaa attccttgct ggaagaaata aaagcgtctt
    13801 tgcataacat ctaccatgag atgcaaagac gggataacta tgtaactgcc gaaaaagtaa
    13861 agaatgagtt tttgggaata gccgagagcc acgaaacgtt attagcttta tttgcaaagc
    13921 acaacgccga tgttgaaaag ttggtaggta tcagtaagac tgctgcgacc ttgcagaaat
    13981 acaaagttac ctataatcat atacagtctt tcctaaaaga caagtataat gtatcggata
    14041 tttctctgaa agaaataaac ctgatgttca ttaatgactt cgaggtttac ctaatgacta
    14101 cctgcaaatg tggtgcaaat acaacagcca agtttatgca attctttaaa cgcataatcc
    14161 tgatagctcg taataacggt ttgttagttg gtgacccgtt tgcaaactat aaaattcggt
    14221 tgaagaaagt cgatagagga tatttgacgg atgaagaaat tactaaaatc ctaaagaaga
    14281 aatttgtatc tgaaagattg gaacacgtgc gtgatatatt tgtattttct tgtttcacag
    14341 ggcttgccta catagacgtt aagaacctga cgcaagataa tatacgcact tcttttgatg
    14401 gtaatctgtg gattatgacc aaacgccaga aaactgatat aaaggtggat gttcctttac
    14461 tcaaaattcc taagatgatt ttagataagt ataaagataa attgccgaac ggattattat
    14521 tgcctatttt aagtaatcag aaaatgaacg cctatttgaa agaaatcggt gatgtttgcg
    14581 gaatacgaaa aacactgaca tttcatcttg caagccatag tgtattttct tttttcttaa
    14641 aaatcaatag cttacaaaat atcccagttt gacaggtaac gatttagaaa ccagcgaaaa
    14701 tctgtattcc acttcgtttt gcagtaattc aaaaga
//
