LOCUS       c00048_gnlPro..         9678 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DIHKIOIP_48.
ACCESSION   c00048_gnlPro..
VERSION     c00048_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 20:47:51
            Original ID  :: gnl|Prokka|DIHKIOIP_48
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9678
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9678
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1178:5402](+)"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1179..5402
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..9678
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..9678
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             3..1061
                     /locus_tag="ctg48_1"
                     /transl_table=11
                     /translation="VDWNAMTAAYRKFLPHIDNNYDFAELLSEWLGELNVSHTGGRYSP
                     RGNGDVTSNLGLLFDWNYQGKGMQIAEIVEKGPFDHSRTKVKAGCIIEKINGEEITPDK
                     DITDLLNNKAGKKTLVSLYNPQNKERWEEVVKPVTSGQLNGLLYKRWVKQRAEDVEKWS
                     GGRLGYVHIQSMGDGSFRTVYSDILGKYNNCDGIVIDTRFNGGGRLHEDIEILFSGQKY
                     FTQVVRGREACDMPSRRWNKPSIMLQCEANYSNAHGTPWVYKHQNIGKLVGMPVPGTMT
                     SVSWETLQDPSLVFGIPIIGYRLPDGSYLENTQLEPDIKVANSPETIVKGEDTQLKMAV
                     DELLKEIDSRKK"
     CDS             1179..5402
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_2"
                     /sec_met_domain="HGD-D (E-value: 1.9e-29, bitscore: 92.0,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 7.3e-36, bitscore:
                     112.6, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKIGIDVGSTTAKLVAVDENDNLLFSKYERHNAKAKETILSFLK
                     ELLSEIGDKDISVRITGSIGMGISEKCSLPFVQEVVAAAKAIQKDYSHVTSMIDIGGED
                     AKVVFFNDAEATDLRMNGNCAGGTGAFIDQMAIILGVNIDELNQLAMNATQVYPIASRC
                     GVFCKTDIQNLIAKNVSRENIAASIFRAVAVQTVVTLAHGCDITTPVLFCGGPLTFIPA
                     LRKAFIDYLSLDEKEIILPANGTLLPALGAALFHLDKEDYCKLSHLIDKIDTTLNGNGN
                     LASTGLEPVFASNEEYEAWKERISRHKMISSGLKAGTQDVFIGIDSGSTTTKIVVLDED
                     SRLLYSYYNINGGNPIKAVEEGLNQLNDECLKQNAVLNIKGSCSTGYGEDLIRSAFQLH
                     SGIIETIAHYMAAHYLNKDVSFILDIGGQDMKVIFVNNGVIDRMEINEACSSGCGSFLE
                     TFAKSLGYSAQEFSLAACHSEAPCDLGTRCTVFMNSKVKQVLREGATINDIAAGLAYSV
                     VKNCLYKVLKLKDISVLGKDIVVQGGTMRNDAVVRAIELLSGAEVARCDTPELMGAFGC
                     ALYAMKHQGESVSLDEIINKAQYSARSLYCKSCDNRCLVIRYEFESGKSYYSGNRCEKV
                     FTNGESSNRKGLNVYRQKEELLFHRSAEIAAPEQIIGIPRCLNMYEEYPFWHTLFTSCG
                     IQVCLSDPSNFRKYEHNARMVMSDNICFPAKLVHSHVQDLIEKKVDRIFMPFVIFERKG
                     MEQNSYNCPIVTGYSEVIKSVQSEGIPVDSPAITFKDRNLLFKQCREYLSGLSVDDRTI
                     QQAFQKAESEQHSFINTLVDYNKNILQQTGKGETLTVMLAGRPYHTDSLIQHKVSDMLA
                     DMGVNVIADDLVRQMDIPTDDAHFVAQWAYTNRILKAAKWCATQGKNIQFVEMTSFGCG
                     PDAFLVDEVRDLLMRHNKSLTLLKLDDINNIGSMKLRVRSMIESLKLANADGTEDGVKD
                     FTTVPVYDKSYRDRKILVPYFTPFISPLIPAIMKVAGYDAENLPLSDNDSSEWGLKYAN
                     NEVCYPATLIVGDIIKALKSGKYDISKIAVAITQTGGQCRASNYISLIKKALVDAGYTD
                     IPVISISVGSDIDNDQPAFKVNWMKVVPITFHAVLYSDCIAKFYYASVVREKEAGASAK
                     LRDKYLQLAPEVILRRDIKGLNSLLQSAITEFNEVCRAVDTPKVGIVGEIFLKFNPFAQ
                     KEIIDWLIGRKIEVVPPILADFFMQGFVNRKVNTDSYIKNRQLPEFIYDWIYKFVKKQI
                     DKINETASKFRYFAPFNDIFEEAEGAKSVISLNAQFGEGWLLPAEIVSYARQGVNNVVS
                     LQPFGCIANHIVSRGVEKRIKSFYPDINLLSLDFDSGVSDVNITNRMLLFIDNLKNATM
                     NYDNN"
     CDS             5389..6012
                     /locus_tag="ctg48_3"
                     /transl_table=11
                     /translation="MTTTNNNEDLEKKIIEAAKELFIENGFAETSMSDIAAKVGINRPA
                     LHYYFRTKDKMFQAVFGNIILSFIPKIHDIIIQQDKPVSESIGEIVDAYYKVFTENPCL
                     PLFMVREMHRDMNHLSTTIKELRLEQYLHKIMDVLQEEMNDGRLKTVPLPFVFYTFYSA
                     LTVPFLTKNLSASFFLEKDDSFEDILVQWKPYIVRQMETLLVAS"
     CDS             complement(6020..6691)
                     /locus_tag="ctg48_4"
                     /transl_table=11
                     /translation="MGMKDVFKRYLVFVIGLYFLAAGIVLIVRSALGTTPISSVNYVLS
                     LNSPLSLGTCTFLINMLLILGQFWVIRKNKTRQDTIEILLQLPFSFIFSAFIDFNMALT
                     SNLHPDNYGMSIALLLTGCMIQSIGVVLELKPKVAMMSAEAFVKYASRRYNKEFGKFKV
                     CFDVTLVTLAVILSLLLSQCIEGVREGSLIAACITGYIVSFLNQKIMTRKTLYKLLPVL
                     K"
     CDS             6848..7738
                     /locus_tag="ctg48_5"
                     /transl_table=11
                     /translation="MVKSRIFDNRQLLKEHPEIPHYKEEVVCFMSEYKDRSYPENERYF
                     NRELYMILVLEGRSEILLNGEFIVIEPDMLLVHGANYLTDHLYSSPDIKFITLSISESM
                     RTDDSYLTQITAILLATMRQNKQYTIQLTAYESQIIRNELEVLMRLLNIKHQFLFRRIQ
                     AACNALFLDIADFLSRKTIIKKEVSRKDHVLQEFHALVTRNFREEHFVSFYADKLAISE
                     QYLARIVRAGTGKSVNTIINELLIMEARTLLSSTKSTVGDIASRLGFSDAAGFCKFFKR
                     NMGQTPLNYRKGLWI"
     CDS             complement(7825..9582)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transketolase_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transket_pyr"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transketolase_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_6"
                     /sec_met_domain="Transketolase_C (E-value: 4e-17, bitscore:
                     51.0, seeds: 80, tool: rule-based-clusters)"
                     /sec_met_domain="Transket_pyr (E-value: 8.6e-18, bitscore:
                     53.3, seeds: 81, tool: rule-based-clusters)"
                     /sec_met_domain="Transketolase_N (E-value: 2.2e-08,
                     bitscore: 22.0, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYLENIYSPADVKKLSFQELNDLSHEIRASLLQKLSEHGGHFGPN
                     FGMVEATIALHYVFNSPKDKIVYDVSHQSYVHKMLTGRKDAFLHPAEYDHVSGYSEPQE
                     SEHDFFVIGHTSTSISLASGLAKGRDLTGGNENIIAVIGDGSLSGGEAFEGLDYVAELG
                     TNMIIIVNDNQMSIAENHGGLYKNLKDLRDSNGQCECNFFKAMGLDYMYVNDGNHVEAL
                     IEAFSKVKDIQHPIVVHINTLKGKGYEPAEQDKETYHWRTPFDLETGESKVNDDAEDYS
                     EVTAQYLLKKMKEDKRVVTITSGTPAVLGFTPDRRQEAGKQFVDVGIAEEHAVALASGI
                     AANGGKPVYGVYSTFIQRSYDQLSQDLCINNNPAVLLVFWGTLSGMNDVTHLCFFDIPL
                     ISNIPNMVYLAPTCKEEYLAMLEWSICQNEHPVAIRVPATDVISCGEPVESDYSNLNRY
                     KVAHRGSKVAILALGSFFGLGQSVLSLLKDKANIDATLINPRYITGVDSELMDELKADH
                     ELVITLEDGVLDGGFGEKIARYYGATDMKVLNYGAKKEFVDRYDIQELLRANHLTDEQI
                     VEDILSLIG"
ORIGIN
        1 gagtggactg gaatgccatg acagctgcct atcgtaaatt cctgccacat attgataata
       61 actatgactt tgcagaatta ctgagcgaat ggttaggtga actgaatgtt tcgcataccg
      121 gagggcgcta ttctccgagg ggcaatgggg atgtaacctc taatctgggc ttattgtttg
      181 actggaatta tcagggaaag ggtatgcaga ttgctgaaat cgtagagaaa gggccgttcg
      241 atcattcccg taccaaagta aaggcagggt gtattataga aaagatcaac ggggaggaaa
      301 taactccgga taaggacatc actgatctct tgaataataa ggcaggaaag aaaacactgg
      361 tttcgctgta caacccgcag aataaggaac gttgggaaga agtggtaaaa cctgtcacaa
      421 gcggacagct taatggctta ttatataaac gttgggtaaa gcaacgtgct gaggatgtgg
      481 agaaatggtc cggcggtcgt ttgggatacg ttcatattca atctatggga gatggcagtt
      541 tccgtactgt ttactcggat attctgggaa aatacaataa ctgtgacgga attgtgatcg
      601 atacccgttt taacggaggc ggtcgtctgc atgaagatat tgaaattctt ttcagcggtc
      661 agaaatattt cactcaggtg gtacgcggac gtgaagcctg tgatatgcca agccgtcgct
      721 ggaacaagcc ttctattatg ttgcagtgtg aagccaatta ttcgaatgcg catggcaccc
      781 cgtgggtgta caagcatcag aatattggaa aactggtagg tatgcctgtt ccgggaacta
      841 tgacaagtgt gtcttgggaa actttgcagg acccttcatt ggtatttggg attcctatca
      901 tcggttatcg tctaccggat ggcagttatc tggaaaatac tcagttggaa cctgatatca
      961 aggttgccaa cagcccggag actatagtga aaggagagga tacgcaactt aaaatggctg
     1021 tggatgaatt gcttaaagaa atagatagtc ggaagaaata gacatcgttc gtttgtgtta
     1081 aaagaaccga aaaaaaagct tattgaaatg atgtgtccaa cttattctta cttttgtgtt
     1141 tgacaatagt gtcaaactag gggaacatag tgtagaacat gattaaaata ggaattgatg
     1201 taggttcaac gacggcgaag ttagttgccg tcgatgaaaa tgataatcta ttattttcaa
     1261 agtacgagag acacaatgcg aaagcaaaag agacaattct atcattcttg aaagagctgt
     1321 tatctgaaat cggagataaa gatatttccg tgaggataac aggctctatc ggaatgggaa
     1381 tttcagagaa atgttcgttg ccgtttgtac aggaggttgt tgcggcagcg aaagcgatac
     1441 aaaaggatta ttctcatgtg acttccatga tagacatcgg aggagaagat gcgaaagtcg
     1501 tcttctttaa tgatgccgaa gcgaccgatt tgcgtatgaa cggcaattgc gcaggaggga
     1561 cgggtgcttt tattgaccag atggcgatta tactgggagt gaatattgat gaattgaatc
     1621 aactagccat gaatgcgaca caggtatatc ctattgcctc ccgttgtggc gttttctgta
     1681 aaacggatat tcagaatctg atagctaaaa atgtaagtcg tgagaatatt gcggcttcca
     1741 tctttcgtgc ggtagcagtt caaacggtag tgacgctggc gcacggttgc gatattacaa
     1801 ctcccgtatt gttttgtggt ggtccgttaa ccttcattcc ggcactgcgg aaagccttca
     1861 ttgattattt gtccctcgat gaaaaagaga tcatactgcc ggccaacggc actttgctcc
     1921 ctgcactagg tgctgctcta tttcatcttg ataaagagga ttactgtaaa ctgtcccatt
     1981 tgatcgataa gattgacact actttaaacg gtaacggtaa ccttgcctca acaggattgg
     2041 aacctgtttt tgcaagtaat gaagaatatg aagcatggaa agaaagaata tcccgtcata
     2101 agatgatatc ttccggcttg aaagccggaa cacaggatgt ctttatcggc atcgattcag
     2161 gttctactac gacaaagatt gttgtactgg atgaagattc aaggcttctg tattcttatt
     2221 ataatattaa tggcggcaat ccgataaaag ctgtggaaga ggggctgaat cagttgaacg
     2281 atgaatgttt gaagcagaat gccgtactca atataaaagg aagctgttct accggatatg
     2341 gggaagacct tatcaggtct gcctttcagc ttcattcggg gattatcgaa acgatcgccc
     2401 attatatggc agcgcattat ctgaacaagg atgtgtcttt tatcctcgat atcggcggac
     2461 aggatatgaa ggttattttt gtgaataatg gcgtgattga ccggatggag attaatgaag
     2521 catgctcttc cggatgtggt tcttttcttg aaacgtttgc taaatctctg gggtattcgg
     2581 cacaagagtt ttctctggca gcctgccatt cggaagcacc gtgtgatttg ggaacaaggt
     2641 gcaccgtttt tatgaactca aaagtgaaac aggtactcag ggagggggca acgatcaatg
     2701 atattgccgc cggactggca tattccgttg tcaagaattg cctgtataag gtgttgaaac
     2761 tgaaagatat atctgttttg ggaaaagata ttgttgtgca gggaggcacc atgcgcaatg
     2821 atgcggtggt ccgtgccatt gaacttctct cgggagcgga agtggcaagg tgtgatacac
     2881 ccgaattgat gggagcattc ggatgtgcat tatatgcgat gaaacatcag ggggagtccg
     2941 tatcattgga tgagattatc aataaagctc aatattcggc acgttcttta tattgcaaga
     3001 gttgcgataa tcgttgtctg gtcattcgtt acgagttcga aagcggcaaa agttattatt
     3061 cgggaaacag gtgcgagaaa gttttcacga atggagagag cagtaaccgg aaaggtctga
     3121 atgtctatcg gcaaaaagaa gagcttttgt ttcatcgcag cgcagagatt gcagcacccg
     3181 agcagattat cggaatcccc cgatgtctga atatgtacga ggaatatcca ttctggcaca
     3241 ctcttttcac ttcctgtggc atacaagtct gtttgtctga tccgtccaat ttcagaaagt
     3301 atgagcacaa tgcgcgtatg gtgatgtcgg acaatatctg ctttccggct aagctggtac
     3361 atagtcatgt tcaggacttg atagaaaaga aggtcgaccg gatttttatg ccttttgtta
     3421 ttttcgaaag aaaagggatg gaacaaaaca gttataattg tccgattgtg acaggttatt
     3481 cggaggttat caaaagtgtg cagtccgaag gtataccggt tgattcccct gcaataactt
     3541 tcaaagaccg gaatctgttg tttaaacaat gccgtgaata tctgagcggt ttgagcgtgg
     3601 acgatcggac gattcagcaa gcattccaaa aagcggaaag cgaacagcac tcttttatta
     3661 atacattggt cgattataac aaaaacatat tgcagcagac tggaaaggga gagactttga
     3721 ctgtcatgct tgccggacgt ccttatcata ccgattctct gatacagcac aaagtctcgg
     3781 atatgcttgc ggatatggga gtgaatgtga tagcggatga tttggtgcgt cagatggata
     3841 taccgacgga tgatgcgcat tttgttgctc aatgggcgta tacgaaccgt atcctgaagg
     3901 ctgcgaaatg gtgtgcgaca caaggaaaga atattcagtt tgtagagatg acttcgttcg
     3961 gatgtggacc ggatgctttt ctggtggatg aagtaaggga tttgctgatg cgtcataaca
     4021 aatcgctgac cttattgaaa ctggatgata tcaataatat cggttcaatg aagttgagag
     4081 tacgttccat gattgaaagc ctcaaacttg cgaatgcgga tggaacggaa gacggtgtaa
     4141 aggactttac gaccgttcct gtttatgaca agtcttaccg tgaccgtaag atactcgttc
     4201 cttactttac tccgtttatt tcacctttga ttcctgctat tatgaaagta gccggttatg
     4261 atgcggaaaa ccttcctctc agtgataatg attcaagtga atgggggttg aagtatgcga
     4321 ataatgaggt ctgttatccg gctactctga tagtcggcga tattataaaa gcacttaaaa
     4381 gcgggaaata tgatatttca aaaatagccg tagccatcac ccaaacggga ggacaatgcc
     4441 gtgccagcaa ctatatttcc ttgataaaaa aggcgttggt ggatgccgga tatacggata
     4501 ttccggtaat ctctatctct gtgggcagtg acatagataa tgaccagccc gcgttcaagg
     4561 tcaactggat gaaagtagta ccgataactt ttcatgccgt tttgtatagt gattgcattg
     4621 ctaagtttta ttatgcgtct gtggtacgtg agaaagaagc aggtgcatcg gcaaagctgc
     4681 gtgataaata cctgcaactg gcacctgaag tgatactgag aagagacata aaggggttga
     4741 actctttgtt gcaatcggca atcactgaat ttaatgaggt atgtagggct gtagatactc
     4801 ctaaagtcgg aattgtagga gaaatcttct tgaaattcaa tcctttcgca caaaaagaga
     4861 tcattgattg gctgataggc cgcaagatag aagtggttcc gccgattctg gctgactttt
     4921 tcatgcaggg gtttgtgaac aggaaagtca atacggattc ttacataaaa aacagacagt
     4981 tgcctgagtt tatttacgac tggatctaca agtttgtaaa gaaacagatt gataaaataa
     5041 atgagacagc aagtaagttc cgttactttg cccccttcaa tgatatcttt gaagaagcgg
     5101 aaggagctaa aagcgttatt tcgctgaatg cccaattcgg tgaaggctgg ttgttgccgg
     5161 ctgaaatcgt gtcttacgcc cggcaagggg tgaacaatgt agtgagtttg caaccttttg
     5221 gctgcatagc gaatcatatc gtatccagag gagtcgaaaa acgtataaaa agtttctatc
     5281 cggatataaa tttgctatct ttagactttg atagtggtgt gagcgacgta aacataacaa
     5341 accgtatgct tttgtttatt gataatctga aaaatgcgac aatgaattat gacaacaact
     5401 aataataatg aagatttgga gaaaaagata attgaggctg ccaaagaact atttatagag
     5461 aatgggttcg cagaaaccag tatgagtgat atcgctgcta aagtaggtat caacagaccg
     5521 gcacttcact attatttccg aacgaaggat aagatgtttc aggccgtttt tggtaatatc
     5581 atactttctt ttattcccaa aatacatgat ataatcattc agcaggacaa acctgtctcc
     5641 gagagtatcg gtgaaattgt agatgcttat tataaagtat tcacggaaaa tccatgtttg
     5701 ccattgttca tggtgaggga gatgcatcgt gatatgaacc atttaagcac tactatcaag
     5761 gagttgcgcc tggaacaata tctccataaa atcatggatg ttttacagga agaaatgaat
     5821 gacgggagac tgaaaacagt tcctttgcca ttcgtattct atacttttta tagtgcattg
     5881 acagttcctt tcctgacaaa gaatctcagt gcttctttct ttttggagaa ggatgattct
     5941 tttgaggata ttctggttca gtggaaacct tatatcgtca ggcagatgga aacgttgctg
     6001 gtagcgagct agagaaaact tatttcaata caggtaataa tttgtagaga gttttccttg
     6061 tcattatttt ctgattcagg aagctgacga tatatccggt gatgcaggcg gcgataagag
     6121 acccctcgcg aacaccttcg atgcattgcg aaagcaggag agagagtatg actgccagag
     6181 tgaccagcgt aacatcaaaa cagactttga actttccgaa ctctttgtta taacggcggg
     6241 aggcgtattt tacaaaagcc tctgcactca tcattgctac tttgggtttg agttcgagta
     6301 cgactcctat ggattgtatc atgcatcctg tgagtaataa ggctattgac attccgtaat
     6361 tgtcgggatg cagattactg gtgagtgcca tattaaaatc aatgaatgcc gaaaagataa
     6421 aagagaacgg caattgaaga agtatttcaa tagtgtcctg tcgggtctta ttttttctga
     6481 tgacccagaa ctgtcccaga ataagcagca tattgatcag aaacgtacaa gttcctaatg
     6541 ataaagggct gttcaggctt agcacataat tgacgctgga tataggtgtg gttcctaatg
     6601 cagaacgcac aatcaacact attccggcag ccagaaaata caatccgata acaaatacca
     6661 aatacctttt aaaaacgtct ttcattccca tatcttacta tcttatataa tcgtattttt
     6721 cttcattcta taaagaagaa tatgcaaagg tcccgttttt tcgtctgata taagttatcc
     6781 gattccacac agtttttgtc atatccgaaa caaatcgtat ttttacgtcg aaaagaagga
     6841 ggtataaatg gtaaaatctc gtatttttga taataggcag ttgttaaagg aacatccgga
     6901 aattcctcat tataaagagg aagtagtctg ctttatgagt gaatataagg acaggagcta
     6961 tccggaaaac gaacgttact ttaatcgtga actttatatg atactcgttc ttgaaggtcg
     7021 ttccgagatt ttgctgaatg gggaatttat tgtgatagag cctgatatgt tgcttgttca
     7081 tggagcgaat tatctcaccg accatcttta ttcgagtccg gatattaagt ttatcaccct
     7141 ctccatttcc gagtccatgc ggacggatga ctcttatctt acccagataa cggctattct
     7201 gttggcaacg atgaggcaga ataagcaata taccatacag ctgaccgcat acgaatctca
     7261 aatcattcgt aatgaactgg aagtgttgat gcgtttgctg aatataaaac atcagtttct
     7321 tttccggcga atacaggcgg cttgcaatgc cttatttttg gatatagccg attttctttc
     7381 ccgaaagact atcataaaaa aggaggtcag tcgtaaagac catgttttac aggaatttca
     7441 tgcgcttgtt acccgaaatt tcagagaaga gcatttcgtt agtttctatg cggataagct
     7501 ggccatcagt gagcagtacc ttgcacgtat cgttcgtgcc ggaacgggaa aaagtgtgaa
     7561 tacgattatt aatgagttac tgatcatgga agcccgtacc ttgctgagtt ccactaaatc
     7621 tacggtaggg gatattgctt cccggcttgg ctttagtgat gctgccggtt tctgtaagtt
     7681 tttcaagagg aatatggggc agactcctct caattatcgg aagggattat ggatttaagt
     7741 gaaaatgaat gtaggttgat gtgatcccat aacgaacgga tacatcaacc tacatgaaat
     7801 atataatgaa ctggttttga cttatcagcc aatgagtgat aggatatctt ctacgatctg
     7861 ttcatccgtc agatggttgg cacgaagcag ttcctgtata tcataacggt ctacaaattc
     7921 ttttttagct ccgtagttga gtactttcat atctgtagcg ccatagtaac gggcaatctt
     7981 ttcaccgaaa ccaccatcca gaactccgtc ttccagggta atcactaatt cgtggtcggc
     8041 tttcagttcg tccatcagtt cgctgtccac acctgtgatg tagcggggat tgataagggt
     8101 ggcatcaatg ttggctttat ctttcagcaa tgacagaacc gattgcccta atccgaagaa
     8161 ggagcctaat gcaagaattg ctactttgga gccgcggtgg gcgactttat aacgattgag
     8221 attgctatag tcggattcca ccggttcacc gcaactgatt acatctgtgg caggtacacg
     8281 gatagccacc ggatgctcat tttggcagat gctccattcc agcatggcta gatattcctc
     8341 tttacaggta ggtgccagat agaccatatt ggggatattg ctgataagcg gaatatcgaa
     8401 gaaacagaga tgcgttacat cattcatacc ggataacgtc ccccagaata ccaacagaac
     8461 agccggatta ttattgatac agagatcttg cgatagctgg tcgtaagagc gttgtataaa
     8521 ggtgctgtac actccgtaaa ccggttttcc gccattggct gcgataccgg aagcaagtgc
     8581 cactgcatgc tcttcggcaa taccgacatc tacaaactgc ttgcctgctt cctgacgacg
     8641 gtcgggagtg aagcctagaa cagcgggggt gcccgaagta atggtaacta cacgcttgtc
     8701 ttctttcatc ttttttagca gatattgagc ggttacttca ctataatctt ctgcgtcgtc
     8761 gttcactttt gattctccgg tttctagatc aaacggagtg cgccagtgat aggtctcctt
     8821 gtcctgttct gcaggctcgt aacctttgcc ttttaatgta ttgatgtgga ctactatcgg
     8881 atgctgtata tctttaactt tggagaaagc ctcgatcagt gcttccacat ggttgccgtc
     8941 attcacgtac atatagtcca gccccatcgc tttgaagaag ttgcattcac attgaccgtt
     9001 actgtcgcgc aaatctttca gattcttgta taaacctccg tgattttcgg caatggacat
     9061 ctgattgtca ttgacaataa taatcatgtt agttccgagt tctgctacgt agtccagtcc
     9121 ctcgaaggct tcgcctccgc ttagtgaacc gtcgcctatt acagcgatga tattttcgtt
     9181 gccacctgtc aggtcacgtc cttttgccag tccgcttgcc aagctgatcg aagtagaagt
     9241 atgaccgatc acaaagaaat catgttcact ttcctgtggt tctgagtagc cggatacatg
     9301 gtcatattca gcaggatgga gaaaagcatc tttacgtccg gtcagcatct tatgtacgta
     9361 actctgatgt gatacatcat atacaatttt atctttcggt gaattgaaaa catagtgcag
     9421 ggcaatggtc gcttctacca ttccgaagtt agggccgaag tgcccgccat gttcactcag
     9481 tttttgtaag agggatgcac ggatttcgtg acttaaatca ttcagttcct gaaacgataa
     9541 cttctttacg tctgcgggag agtaaatatt ttctaaatac atatcaaatt gtttttttat
     9601 gtttatacct atatttttat ttcactgcaa agatactgcc ggatttgaaa tctgtttgta
     9661 tatgaattac ggattctt
//
