LOCUS       c00071_gnlPro..        12823 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KCBGJHOB_71.
ACCESSION   c00071_gnlPro..
VERSION     c00071_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 20:18:24
            Original ID  :: gnl|Prokka|KCBGJHOB_71
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12823
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..528)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg71_1"
                     /sec_met_domain="POR (E-value: 1.9e-35, bitscore: 114.9,
                     seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQEIIIAGFGGQGVLSMGKILAYSGLMEDKEVTWMPAYGPEQRG
                     GTANVTVIVSDERISSPILSQYDTAIILNQPSLEKFEGKIKPGGILIYDGYGIIEPPTR
                     RDIRIYRIDAMDAANEKGMAKTFNMIVLGGLLKLRPVVSIESVIKALRKTLPERHHHLI
                     PMNEEAIRIGMEI"
     protocluster    1..12823
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:2823]"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1..2823
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
     cand_cluster    1..12823
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Fer4_7 and TPP_enzyme_C and POR and
                     POR_N and PFOR_II and not (EKR or Fer4_16))"
                     /kind="single"
                     /product="porA"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12823
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="porA"
                     /region_number="1"
                     /rules="(Fer4_7 and TPP_enzyme_C and POR and POR_N and
                     PFOR_II and not (EKR or Fer4_16))"
                     /tool="gutsmash"
     CDS             complement(542..1306)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg71_2"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2e-25, bitscore:
                     81.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKEEIIKPENLVYKKPTLMNDNPMHYCPGCSHGVVHKLIAEVIE
                     EMGMEDKTIGVSPVGCAVFAYNYLDIDWQEAAHGRAPAVATAIKRLWPGRLVFTYQGDG
                     DLACIGTAETIHALNRGENITIIFINNAIYGMTGGQMAPTTLVGMKTATCPYGRDVAIH
                     GYPLKMTEIAATLEGTAYVTRQSVHTVPAIRKAKKAIRKAFENSMNGKGSNLVEIVSTC
                     NSGWKMTPQASNDWMVEHMFPFYPLGDLKNKE"
     CDS             complement(1325..1492)
                     /locus_tag="ctg71_3"
                     /transl_table=11
                     /translation="MNIDLIRNILNILFMALALAAVITYFVASDFKVFIYVCAAAIFLK
                     LVEFFMRFML"
     CDS             complement(1499..2581)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg71_4"
                     /sec_met_domain="PFOR_II (E-value: 7.2e-29, bitscore: 92.6,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 3e-51, bitscore: 166.8,
                     seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEEVVLMKGNEAIAHAAIRIGVDGYFGYPITPQSEILETLAEEK
                     PWETTGMVVLQAESEVAAINMVYGGAASGKMVMTSSSSPGVSLKQEGISYIAGAELPCL
                     IVNVMRGGPGLGTIQPSQADYFQTVKGGGHGDYRLIALAPASVQEMADFVGIAFDLAFK
                     YRNPAIILADGVIGQMMEKVVLPEQRTRLTDEEVIARCPWATTGRTHHRTPNIITSLEL
                     DPAEMEKRNIHLQKKYAEIEENEVRFEELHCEDSEYLIVAFGSCARIAQKAMEMAREEG
                     IKVGLLRPITLWPFPSKAIAARAAQVKGILTVELNAGQMVEDVRLAVKCKVPVEHFGRL
                     GGIVPDPDEVITALKEKLIK"
     CDS             complement(2593..2823)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg71_5"
                     /sec_met_domain="Fer4_7 (E-value: 1.6e-12, bitscore: 40.4,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 2e-08, bitscore: 26.5,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 2.4e-08, bitscore: 26.4,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.1e-05, bitscore: 18.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKIKGAIVVDTERCKGCNLCVVACPLHVIALNAKQVNKKGYTFA
                     HQVLEDTCNGCASCATVCPDGCITVYKVKQQ"
     CDS             complement(2834..3130)
                     /locus_tag="ctg71_6"
                     /transl_table=11
                     /translation="MRQSCLMTEELQDIKTLIEQGDTERAIHALTNFIRNDAHVNDEPY
                     YLLGNAYRKMGNWQQALNNYLEAIERNPESPAVSARDMIMNILNFYNKDMYNQ"
     CDS             3248..3409
                     /locus_tag="ctg71_7"
                     /transl_table=11
                     /translation="MISSNGLIIIEMVSSETVDRGTVLFILKGGICLNCICHDIFGGKY
                     MVNRLYVF"
     CDS             complement(3500..4597)
                     /locus_tag="ctg71_8"
                     /transl_table=11
                     /translation="MKKILFLMLLCLPFIAMAQTDPKYLAGAITLDDGKVSFKTEIQAP
                     SLTKDQLYETMLKWATERFKPEGKFNARVLYTNEDEGTIAAGGEEYLVFSSSALSLDRT
                     RIYYQMFITCGNGKCDIEMTRIRYWYDEARDGGEKYSAEEWIVDDMALNKSKTKLAPIC
                     GKFRRETIDLKDTLFKSIQDTLGNKVLNNSQIAVAPTSGVTATPISNTTTIITATPVTP
                     PAQPAIIGGSEGNTEIKVANNVTPSKEQSIDDQIKASSRMTITAGNDEQFEIGKECWGG
                     FGQLFGKEVAFCIIDQSKSMGNMLMDQSDNYKISFYKQGSSEPWLIVNCKKLMKQTVTG
                     EEAKKMNPSNNGQKAYNMYVGEVIK"
     CDS             complement(4704..5138)
                     /locus_tag="ctg71_9"
                     /transl_table=11
                     /translation="MKKVGLASDHAGFELKEFVKTWLTEKGYPCKDFGTYSTESCDYAD
                     YAHPLALAIEAGECGPGVAICGSGEGISMTLNKHQGIRAALCWIPEIAHLSRQHNDANV
                     LVMPGRFIDHEMAEKILDEFFNSGFEGGRHQKRIEKIPVK"
     CDS             complement(5135..7147)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transketolase_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transket_pyr"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transketolase_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg71_10"
                     /sec_met_domain="Transketolase_C (E-value: 1.6e-08,
                     bitscore: 27.0, seeds: 80, tool: rule-based-clusters)"
                     /sec_met_domain="Transket_pyr (E-value: 1.6e-35, bitscore:
                     114.8, seeds: 81, tool: rule-based-clusters)"
                     /sec_met_domain="Transketolase_N (E-value: 6.3e-96,
                     bitscore: 313.6, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNEKKLMNRAADNIRILAASMVEKANSGHPGGAMGGADFVNVLFS
                     EFLVYDPENPRWEGRDRFFLDPGHMSPMLYSTLALTGKFTMEELAQFRQWGSPTPGHPE
                     VDIMRGIENTSGPLGQGHTFAVGAAIAAKFLKARLGNVMDQTIYAYISDGGIQEEISQG
                     AGRLAGHLGLDNLIMFYDSNDIQLSTATDAVTSEDVAKKYEAWHWKVIIINGNDPDAIR
                     TALTEAKAVTGQPTLIIGKTIMGKGARKADDSSYERNCATHGAPLGGDAYINTIKNLGG
                     DPTNPFQIFPEVKELYAKRAEELKKIVAEKYAAKAEWTKANPELAAKLELWFSGKAPKV
                     NWNAIEQKAGDATRSASAKVLGVLATEVENMIVSSADLSNSDKTDGFLKKTHAFTKDDF
                     TGAFLQAGVSELTMACCCLGMALHGGVIAACATFFVFSDYMKPAVRMAALMELPVKFIW
                     THDAFRVGEDGPTHEPVEQEAQIRLMEKLKNHKGHNSMLVLRPADAEETTVAWKLAMEN
                     TSTPTALIFSRQNIANLPAGNDYSQAAKGAYIVAGSDENPDIILVASGSEVSTLEAGAE
                     LLRKDGIKIRIVSAPSEGLFRSQSKEYQNSVIPTEAKVFGLTAGLPVNLEGLVGANGKV
                     FGLESFGFSAPYKVLDEKLGFTAQNVYNQVKEMLA"
     CDS             complement(7282..8880)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg71_11"
                     /sec_met_domain="FGGY_C (E-value: 6.1e-30, bitscore: 96.8,
                     seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="FGGY_N (E-value: 7.3e-20, bitscore: 64.0,
                     seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSDAKSTIEAGKAILGIEFGSTRIKAVLIDQENKPIAQGSHSWE
                     NQLVDGLWTYSVEAIWHGLQDCYADLRSNVKKLYDTEIETLAAIGVSAMMHGYMAFNKE
                     EEILVPFRTWRNTNTGPAAAALSELFVYNIPLRWSISHLYQAILDNEEHVSDIDYLTTL
                     AGFIHWQITGQKVLGIGDASGMLPIDPATKNYSAGMIAKFDKLVAPKGYPWKLTDILPK
                     VLPAGENAGFLTPEGAKRLDVSGHLKAGIPVCPPEGDAGTGMVATNAVKQRTGNVSAGT
                     SSFSMIVLEKELSKPYEMIDMVTTPDGSLVAMVHCNNCTSDLNAWINLFKEYQELLGIP
                     VDMNELYGKLYNHALAGDADCGGLISYNYISGEPVTGLADGRPLFVRSANDKFSLANFM
                     RTHLYASVGVLKIGNDILFNEEKIKVDRITGHGGLFKTKGVGQRILAAAINSPISVMET
                     AGEGGAWGIALLGSYLVNNEKKQSLADFLEDKVFAGDAGIEISPTAEDVAGFNTYIENY
                     KAGLPVEEAATQFKK"
     CDS             complement(8983..10512)
                     /locus_tag="ctg71_12"
                     /transl_table=11
                     /translation="MEKAFDQYEVWFVTGAQLLYGGDAVVAVDAHSNEMVNGLNESGKL
                     PVKVVYKGTANSSKEVEAVFKAANNDEKCIGVITWMHTFSPAKMWIHGLQQLKKPLLHL
                     HTQFNKEIPWDTMDMDFMNLNQSAHGDREFGHICTRMRIRRKVVVGYWKDEDTQHKIAV
                     WMRVCAGWADSQDMLIIRFGDQMNNVAVTDGDKVEAEQRMGYHVDYCPASELMEYHKNI
                     KDTDVEALVATYFNEYDHDASLEDKSTEAYQKVWNAAKAELALRAILKAKGAKGFTTNF
                     DDLGQTDGSYFDQIPGLASQRLMAEGYGFGAEGDWKSAALYRTVWVMNQGLSQGCSFLE
                     DYTLNFDGANSAILQSHMLEVCPLIAASKPRLEVHFLGIGIRKSQTARLVFTSKVGSGC
                     TATVVDLGNRFRLIVNDVECIEPKPLPKLPVASALWIPMPNFEVGAGAWILAGGTHHSC
                     FSYDLTAEYWEDYAEIAGIEMIRIDKDTTISNFKKELRMNEVYYMLNKALC"
     CDS             complement(10552..11304)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldolase_II"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg71_13"
                     /sec_met_domain="Aldolase_II (E-value: 3.6e-53, bitscore:
                     172.7, seeds: 389, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCRCNNLPIDKLAYCHITQLFIMLEKLKEKVFRANLDLVKHGLVI
                     FTWGNVSAIDRETGLVVIKPSGVSYDDMKAEDMVVVNLDGNVVEGSLRPSSDTPTHVVL
                     YKAFPEIGGVVHTHSTYATAWAQAGMDIPNIGTTHADYFHDAIPCTADMTEEEVKGAYE
                     QETGNVIVKRFKKLNPVHTPGVLVKNHGPFAWGKDANDAVHNAVVMEQVAKMASIAFAA
                     NPHLTMNSLLIEKHFSRKHGPNAYYGQK"
     CDS             complement(11309..11986)
                     /locus_tag="ctg71_14"
                     /transl_table=11
                     /translation="MTTYYNINPKFYVSVDCIIFGFDEGELKLLLLKRNFEPAMGKWSL
                     MGGFVQEDESVDAAAKRVLAELTGLENVYMEQVGTFGDLERDPGERVISVAYYALVNVN
                     EYDRELVQQHNAHWTKIDELPQLIFDHPIMISKARELMKHKASYNPIGFNLLPELFTLT
                     QLQNLYEAIYGEPMDKRNFRKRVAEMDFIEKTDLIDKSGSRRGAYLYKFNDKAYRKDPK
                     FKL"
ORIGIN
        1 aatctccatt ccgattcgga tggcttcttc attcatcggt atcagatgat ggtgacgttc
       61 gggtaatgtt ttgcgtaaag cttttattac actttcaatg gatactacgg gacgtagttt
      121 tagcaagcct cctaagacaa tcatgttgaa ggtctttgcc attccttttt cgttggcggc
      181 atccattgcg tcaatacgat agattcgtat gtccctacgt gtcggaggct cgatgattcc
      241 gtatccgtca taaatgagaa taccacctgg tttaattttg ccttcaaact tttccaatga
      301 gggttggttc agtatgatgg ctgtgtcata ttggctgaga atgggtgaag agatgcgttc
      361 atcactgaca atcaccgtta cgttagcggt tcctccccgt tgttcgggac cgtatgccgg
      421 catccaggtt acttccttgt cttccatcag tccggaatag gcaagtatct tacccatgga
      481 tagcacaccc tgaccgccga atcctgctat aatgatttcc tgtttcatgg tttctgtctt
      541 tttattcttt atttttcaaa tcacccagcg gatagaaagg gaacatgtgt tccaccatcc
      601 agtcattgga tgcttgcgga gtcattttcc aaccggaatt acaagtcgat acaatttcca
      661 ccaaattaga acctttgcca ttcattgaat tttcaaatgc cttgcggata gcctttttgg
      721 ctttgcggat ggcgggaact gtatgtacgg actggcgggt aacgtaggcg gtgccttcca
      781 aagtggcggc aatttctgtc attttcagcg gatagccgtg aatggctaca tcacgaccat
      841 aggggcaggt ggctgttttc atgccaacca gagtggtagg agccatttgc ccaccggtca
      901 ttccataaat ggcattgttg ataaagatga tagtaatgtt ttcaccacga tttaaagcat
      961 ggatagtttc ggcagtaccg atacatgcca agtcaccatc tccttggtag gtaaatacca
     1021 gacgtccggg ccataaacgc ttaatggcgg tagctacggc tggtgcgcgt ccgtgggcgg
     1081 cttcttgcca atcgatgtct agataattgt atgcaaatac ggcacatcct actggtgaca
     1141 caccgattgt cttatcttcc atgcccattt cttcaataac ttcggctatt aacttgtgaa
     1201 ccacaccgtg gctgcatccg gggcaataat gcatcggatt gtcattcatc agtgtcggtt
     1261 tcttataaac caggttttcg ggttttatga tttcttcttt tgtcatagtt tctcctccta
     1321 ttgtttataa catgaaccgc ataaagaatt ccaccagctt gagaaaaata gctgctgcac
     1381 agacatagat gaatactttg aagtcacttg ccacaaagta agtgatgaca gctgctaatg
     1441 ccagtgccat gaaaagtatg ttcaatatat ttctgatcag atcgatattc atacggtctt
     1501 attttattag tttctctttc agtgcagtga ttacttcatc cggatcgggg acaataccac
     1561 ccagacgtcc gaagtgttct acaggcactt tacattttac agccagacgg acatcttcta
     1621 ccatttgtcc ggcgttcaat tctacagtga ggataccttt tacctgtgcg gcgcgtgctg
     1681 caatagcttt cgacgggaac ggccataggg taataggacg gagcaaacca actttgatgc
     1741 cttcttcccg agccatttcc attgcctttt gggcaatgcg ggcgcaagag ccgaaagcta
     1801 cgatcaaata ttctgaatct tcgcagtgaa gttcttcgaa gcgtacttca ttctcttcta
     1861 tttctgcata ttttttctga agatgaatat tgcgcttttc catttcggcg ggatcgagtt
     1921 ctaatgaggt aatgatgttg ggggtacggt ggtgggttct gccggtagtg gcccacggac
     1981 aacgggcaat gacttcttca tctgtcaggc gtgtgcgctg ttcgggtaat actacttttt
     2041 ccatcatctg cccgataacg ccatctgcca gaataatggc gggattgcgg tatttgaaag
     2101 ccaaatcaaa agctatacct acgaaatctg ccatttcctg tactgatgca ggtgccaggg
     2161 ctatgagacg atagtctccg tgaccgccac ctttcactgt ttggaaatag tcggcctgac
     2221 taggttggat ggttcctaat ccgggacctc cgcgcatgac attgacaatc aggcagggga
     2281 gttcggcacc ggcaatgtac gagatgcctt cctgctttaa actaacgccg ggactggagg
     2341 atgaggtcat taccatttta ccgcttgctg caccgccata taccatgttg attgctgcga
     2401 cttcactttc tgcctgtaac accaccatac cggtagtttc ccaaggtttc tcttcggcca
     2461 gcgtttccaa tatttccgat tggggagtga tgggatagcc aaagtaaccg tctactccga
     2521 tacggatggc ggcgtgggct atggcttcat ttcccttcat taaaacgact tcttctgcca
     2581 tatttgttac atttattgtt gttttacttt atacacagta atgcatccgt ccggacagac
     2641 tgtggcacat gatgcgcaac cattgcaggt atcctctaat acctggtggg cgaatgtgta
     2701 tcctttttta ttcacttgtt tggcattgag cgcgattaca tgtagcggac atgccactac
     2761 acatagattg caacctttgc aacgctctgt gtctactaca atagcacctt taatctttgc
     2821 catgggttag ttattattga ttatacatgt ctttgttata gaaattcaga atattcataa
     2881 tcatgtcacg ggcggaaacg gcgggacttt ccggattacg ctcgatggct tccaaataat
     2941 tgttcaaagc ttgttgccag tttcccattt tgcggtaggc gttacccagt aagtaatagg
     3001 gttcatcgtt gacgtgcgca tcgtttcgga tgaaattagt tagcgcatga atagctctct
     3061 ccgtatcacc ctgttcgata agtgtcttta tgtcctgtaa ttcttccgtc ataaggcatg
     3121 attgtctcat tgttgtttac aaagatactc tttatttgtt atgaaaggga agattggagc
     3181 agaaaaaacg actttcttgc taaaaacatt taaaaaaagg agagaaagat agggaaaaaa
     3241 tggaagaatg atttcttcta atggtttgat tattatagaa atggtttcaa gtgaaacggt
     3301 tgatagagga acggtgttat ttattcttaa aggggggata tgtttgaatt gtatttgtca
     3361 tgatattttt ggggggaagt atatggtaaa tcgtttgtat gttttttagg gggagttgtc
     3421 aggttatctc cccccctaaa tattttatgt attatcgtat agaattaact gtcacggcat
     3481 aaatatatag aagaaaagat tattttatta cttcacctac atacatatta tatgccttct
     3541 ggccgttgtt actggggttc attttttttg cttcctcacc ggtaactgtc tgtttcatca
     3601 gtttcttaca gtttactatc aaccacggct cactactacc ttgcttgtag aacgaaattt
     3661 tataattgtc gctttgatcc attagcatat tgcccattga tttggattgg tcaattatgc
     3721 agaatgctac ttctttgccg aataactgac cgaaacctcc ccaacattct ttaccaattt
     3781 cgaattgttc atcgtttccg gcagtaattg tcatacgtga agatgccttg atttggtcat
     3841 ctatgctttg ttctttgcta ggagttacat tattggctac ttttatttcg gtattaccct
     3901 cagaaccacc gatgatagcc ggttgggcag ggggagttac cggagtggcg gtaatgattg
     3961 tggttgtatt tgatatcgga gtggctgtta cacccgaagt aggagcaact gcaatttgtg
     4021 agttgttcaa gactttgttg cccaatgtat cttggatgga tttgaacagt gtgtctttca
     4081 agtcaattgt ttctcttctg aatttgccgc agatgggagc cagtttggtt ttcgatttgt
     4141 ttaaagccat atcgtctaca atccattcct ctgcgctgta tttttctcct ccgtcacgag
     4201 cttcatcata ccaatagcgg atacgggtca tttcgatatc acattttccg tttccgcagg
     4261 tgataaacat ctgataataa attctggttc tgtccaatga caatgcagag gatgagaata
     4321 ccagatattc ttcgccacct gctgcaatgg ttccttcatc ttcattggtg taaagaacac
     4381 gtgcattgaa cttgccttcg ggcttgaaac gttctgtagc ccatttcagc attgtctcat
     4441 atagctggtc tttcgttaaa gacggtgcct gtatttctgt tttgaaagaa actttaccgt
     4501 catccaaagt tattgctccc gccagatatt tgggatctgt ctgtgccata gcgatgaatg
     4561 gcaggcataa gagcattaaa aaaagaattt tcttcatagt aatatatctt attttatatt
     4621 ttaatctaag caaagatagg aataaaaaaa aagagaagct ataaagcctc tcttttttta
     4681 cttttattat tattgcgtga attttacttt acaggtatct tttcaatgcg tttttggtga
     4741 cgtccgcctt caaagccgct gttaaagaat tcatctaata ttttttcagc catttcatgg
     4801 tctatgaatc gtcctggcat taccagaaca ttggcatcat tgtgttgacg tgacaaatgg
     4861 gctatctcgg gaatccagca tagtgccgca cggataccct gatgtttgtt caatgtcatg
     4921 ctgatccctt caccgcttcc gcaaatagct actccgggtc cgcattctcc ggcttctata
     4981 gccagtgcaa gcggatgggc gtaatctgca tagtcacagc tttctgtact gtatgtaccg
     5041 aaatctttgc atggataacc tttttcagtc aaccatgttt ttacaaactc tttcagttca
     5101 aatcctgcat gatcggatgc cagtcctact tttttcatgc cagcatttct tttacttggt
     5161 tatacacgtt ctgtgcggta aagcccagct tttcatccaa tactttgtaa ggagcggaga
     5221 atccgaatga ttccagaccg aatactttac cgttggcacc taccaaacct tcaaggttta
     5281 caggaagacc ggcagtcaga ccgaatactt tagcctctgt gggaatgaca ctgttttggt
     5341 attccttgct ttggctgcgg aacaatccct cagaaggagc ggatacgata cgtattttta
     5401 tgccatcctt gcggagaagt tctgcacctg cttccaaagt ggaaacttcg gaacctgaag
     5461 cgactaggat tatatccgga ttttcgtcgg aacctgcaac aatataagcg ccttttgcag
     5521 cctgtgagta gtcgtttcct gcaggcagat tcgcgatatt ctggcgggag aagattagtg
     5581 cggtgggggt gctggtattt tccatggcca atttccacgc tacagtggtc tcttccgcat
     5641 ctgccggacg gagtaccaac atagaattgt gccctttgtg gtttttcagt ttttccatca
     5701 ggcggatttg tgcttcttgt tctaccggtt cgtgagtagg accgtcttca cctacacgga
     5761 atgcgtcgtg tgtccagatg aacttgacgg gaagttccat caaggcagcc atacgtacgg
     5821 cgggtttcat atagtctgag aatacgaaga aagtagcaca tgcagcaatc acgcctccgt
     5881 gaagtgccat acctaggcag cagcaagcca tggttaattc ggaaacacct gcttgcagaa
     5941 acgcgccggt gaagtcatct ttagtgaatg catgtgtttt cttcaagaaa ccgtcggtct
     6001 tgtctgagtt tgacaggtcg gccgaagaaa caatcatgtt ttctacttct gtagctagta
     6061 caccgagaac tttggcagaa gcactgcgtg tagcatctcc ggctttttgt tcaatagcat
     6121 tccaatttac tttcggagct ttgcctgaga accacagttc caatttagct gccagttcgg
     6181 gattagcttt agtccattca gctttagctg catatttttc tgcaacaatt tttttcagtt
     6241 cttctgcacg tttggcatac aactctttta cttcagggaa gatttggaaa ggattggttg
     6301 gatcgccacc taagtttttg attgtattga tgtaagcatc acctcccaaa ggggcaccgt
     6361 gggtggcaca gttacgttca taactggaat catccgcttt gcgtgcacct ttacccataa
     6421 tggtcttacc gataattaat gtgggctgac cggttacggc tttcgcttct gtcagagctg
     6481 tgcggattgc atcgggatca ttaccattga taataattac tttccagtgc catgcttcgt
     6541 atttcttggc aacatcttcg ctggtaacag catcggtagc ggtagacagc tggatgtcgt
     6601 ttgaatcata aaacatgatc agattgtcca gtcccaaatg acctgccaaa cgtcctgcac
     6661 cctgagaaat ttcttcttga atgccaccat cggatatata ggcatagata gtctggtcca
     6721 tgacattacc cagacgggct ttcagaaatt tggcagcgat agcagcacct actgcaaaag
     6781 tgtgtccttg tcctaacgga ccggaagtat tttcaatacc gcgcatgatg tccacttcag
     6841 ggtgtcccgg agtcggactt ccccattgac ggaactgtgc cagttcttcc atggtgaact
     6901 tgccggtcag tgccaaagtg gaatataaca tcggtgacat gtggcctgga tcaaggaaga
     6961 aacggtcacg tccttcccaa cgcggatttt caggatcgta aactaaaaac tcagagaaaa
     7021 gtacattcac aaaatcagcg ccacccatag ctccacccgg atgtcctgaa ttagctttct
     7081 ctaccatcga agcagccaga atacggatgt tgtccgctgc acggttcata agtttctttt
     7141 cgttcatatt aaaataatat tataatttga atgctattag tgagtcggtt tatccttgct
     7201 attttattta atatctgcaa agataactct ttatgtgtaa accacaacat gtaaagaggc
     7261 tcttttttaa acctgtttga ctcacttctt aaattgggtc gctgcttctt caacaggcag
     7321 tcctgcctta tagttttcga tatatgtgtt gaatccggct acatcttcgg ctgttggcga
     7381 tatttcaata ccggcatcac cggcgaatac tttgtcttcc agaaaatctg ccagggattg
     7441 tttcttttca ttgttgacaa ggtaagaacc tagcagggcg attccccatg cgccaccttc
     7501 accggcagtt tccattacgg aaatagggga gtttatagct gctgcaagta ttctctggcc
     7561 tacacctttc gtcttgaata atccgccgtg tcctgtgatt ctgtctactt tgattttctc
     7621 ttcattgaaa agaatgtcat tacctatctt aagaactccg actgaagcgt ataaatgggt
     7681 acgcatgaag ttggcgaggc tgaatttgtc atttgcagaa cgtacaaaca atggccttcc
     7741 gtcggcaagt cctgtcacgg gttcacctga aatataatta tatgaaataa gaccaccgca
     7801 atctgcatca cctgcgagcg catgattgta aagttttcca tataattcat tcatatctac
     7861 aggtataccc agcagttctt ggtattcctt aaacagattg atccaggcat tgaggtcgga
     7921 ggtgcagttg ttgcaatgta ccatagctac aaggcttccg tcgggagtgg tgaccatgtc
     7981 aatcatttcg tatggcttgg acaactcttt ttccaacaca atcatggaaa atgaggaagt
     8041 gcctgctgat acattcccgg tacgttgctt gacagcgttg gttgctacca tgccagttcc
     8101 ggcatctcct tccggaggac agacaggtat acctgctttt aaatggcccg acacgtccag
     8161 cctcttggca ccttctggtg taaggaaccc tgcattctcg ccggcgggta agactttggg
     8221 caggatatct gtcagtttcc aggggtatcc tttaggagct accaacttgt cgaacttggc
     8281 tatcattccg gcagaataat tcttggtagc cgggtctatg ggaagcattc ctgatgcatc
     8341 acctatgccc agaacttttt gacctgtaat ttgccaatga atgaaacctg caagggtggt
     8401 cagatagtca atgtcactta cgtgctcttc attgtctaaa atagcttggt ataaatgaga
     8461 aatgctccat ctcagaggaa tattatatac gaataattca gataaagcgg ctgctgccgg
     8521 accggtattg gtgtttctcc atgtacggaa aggtacaagg atttcttctt ctttattgaa
     8581 tgccatataa ccatgcatca tggcactgac accgattgct gccaaggttt ctatttctgt
     8641 gtcatatagc ttttttacgt tggaacggag atctgcatag cagtcttgca ggccatgcca
     8701 gatagcttcc acactgtaag tccacagtcc gtctaccaat tgattttccc agctatggct
     8761 tccttgggca atgggcttgt tttcctggtc aatcaaaaca gctttgattc gcgttgatcc
     8821 gaattctatg cctagaatag cttttcctgc ttcgatggtt gattttgcat ctgatttcat
     8881 attaaaacct ataatttaag gtacaacaat aatgatgata aaataaggtg ggatgtgcca
     8941 agaatcttat tagccttgac acatcccctc ttcatggatg aattagcaaa gtgctttgtt
     9001 cagcatatag tagacttcgt tcatgcgaag ctctttcttg aagttgctga tggtagtatc
     9061 tttgtcaata cggatcattt cgatacctgc aatttcagca tagtcttccc aatattctgc
     9121 tgtcagatca taagagaagc aagaatgatg tgttccacct gccaggatcc atgcgcctgc
     9181 acctacttcg aaattaggca tcggaatcca cagggcggaa gcaaccggta atttgggcaa
     9241 cggtttcggt tcgatgcatt ctacgtcgtt cacgatcaga cggaaacggt tacccaagtc
     9301 tactacagtg gcggtacaac ctgaacctac ttttgaagtg aatacaagac gggctgtctg
     9361 gctcttgcga atacctatac ctaggaagtg tacttccaga cgtggtttgg aagcggcgat
     9421 aagaggacaa acttccagca tatgtgattg caggatagca ctgtttgcac catcgaagtt
     9481 caatgtgtaa tcttccaaga aagaacaacc ttgggaaagt ccttggttca tcacccatac
     9541 agtgcggtag agagctgctg atttccagtc accttccgca ccgaatccgt agccttcagc
     9601 catcagacgc tgggaagcca gtcccggaat ctgatcgaag tagctgccgt ctgtttggcc
     9661 caaatcatca aaattagtag tgaatccttt agcgcctttg gctttgagga tggcacgaag
     9721 agctaattcg gcttttgcag cattccatac tttctgataa gcttcggttg atttatcttc
     9781 taatgaagca tcgtggtcgt attcgttaaa gtaagttgct acaagtgctt ctacatctgt
     9841 atccttgata tttttatggt attccatcag ttcgcttgcc ggacagtaat ctacgtggta
     9901 ccccatacgt tgttctgctt ccactttatc accgtcagtt acagctacat tattcatctg
     9961 atcgccgaaa cggatgatca gcatatcctg agagtctgcc caacctgcac aaacgcgcat
    10021 ccaaacggca atcttgtgct gggtgtcttc gtctttccag taacctacca ctactttgcg
    10081 gcggatgcgc atacgggtac agatatgtcc gaattcgcgg tcaccatggg cggattgatt
    10141 cagattcatg aagtccatat ccatggtatc ccaaggaatt tccttattga attgagtgtg
    10201 tagatgtaac agtggtttct ttaactgctg cagaccgtga atccacattt tagcagggga
    10261 gaaagtgtgc atccaagtga tgacaccgat acatttttca tcgttgttgg ctgctttgaa
    10321 cactgcttcc acttctttag aagaattggc tgttccttta tatactactt ttacaggaag
    10381 tttccctgat tcgttcaatc cgtttaccat ttcattggag tgagcgtcta ctgctacaac
    10441 tgcgtcacct ccgtacagaa gctgtgctcc tgttacaaac catacttcat actgatcaaa
    10501 tgctttttcc ataatgttat attttaaaag ggttattaat ttctttgttt cttatttctg
    10561 tccataatag gcattggggc cgtgtttgcg gctgaaatgc ttttctatta ataaagaatt
    10621 catcgttaaa tgagggttgg cggcaaaagc gatacttgcc attttggcta cctgttccat
    10681 gactactgca ttatgcacag catcattggc atcttttccc catgcaaaag gaccatgatt
    10741 ttttactagt actcccggag tatgtacagg gttcagtttc ttgaaacgtt tcacaatcac
    10801 attgcctgtt tcctgttcat aggcaccttt tacttcctct tctgtcatat ctgcggtaca
    10861 aggaatggcg tcatggaaat aatcggcatg agtcgttccg atattgggaa tatccattcc
    10921 ggcttgtgcc caggcggtgg cataggtgga gtgggtatgt accactccac ctatttcggg
    10981 gaatgcttta tatagaacta catgggtggg agtatctgaa gacggacgaa gagaaccttc
    11041 taccacgttg ccgtccagat ttactacaac catgtcttca gctttcatat catcgtatga
    11101 tacaccactg ggtttgatta ctaccaagcc tgtttcacga tcaatggcag aaacatttcc
    11161 ccatgtaaaa ataactagtc cgtgtttcac caaatccaga ttggcacgga atactttttc
    11221 ttttaatttt tctaacataa tgaataattg ggtaatgtgg caatatgcta atttgtcaat
    11281 tggcaaatta ttgcatcggc acattatttt aaagtttaaa tttcggatcc tttctgtagg
    11341 ccttatcatt aaatttataa agataagcac ctcgtcggga acctgatttg tctatcaaat
    11401 ctgttttttc aatgaaatcc atttcggcta cccgcttgcg gaaattccgc ttgtccatcg
    11461 gttcgccata gattgcttca tatagatttt gcaactgtgt cagggtaaac aattcgggca
    11521 gcaggttaaa accaattgga ttgtatgatg ctttgtgctt cattagttca cgtgctttgg
    11581 aaatcatgat cggatgatcg aaaatgagct gtggcagttc gtctattttt gtccaatggg
    11641 cattgtgctg ctgcactagt tccctgtcat attcatttac attgactaaa gcataatagg
    11701 ctactgatat aactcgttct cctggatcgc gctctaagtc gccaaatgtg cctacttgtt
    11761 ccatatatac attttccaat ccggtcagtt ctgccaatac ccgtttggcg gcagcgtcta
    11821 cactttcgtc ttcttgtacg aatcctccca tcaaagacca ttttcccata gctggttcaa
    11881 aatttcgttt tagtagaagc agttttaatt ctccttcgtc aaaaccgaaa atgatacagt
    11941 ctacagatac atagaattta ggatttatgt tataataggt ggtcatggtt tagtgtcggt
    12001 ttaaaattaa caggctgtat tcttcaagat aattcaaagc atacagcctt taatttatgg
    12061 tttaccagaa ataagcatag aatagtgcgc aaagcagaac tacacctaaa gaggttataa
    12121 catcccattt gttccagctc tttctgataa gttccttgta actgccggta aaggtgatgg
    12181 cttccacttg tttggcggtt ggagccggag tgaagcatga tacaacaacc attaacaaca
    12241 aaaggaatac aagtaaccat atttcaaaaa taagccagtt tgtctgccaa aaccaagttg
    12301 tattttccca aaaccagccg gtcatcacat cttttccggt gttggtgagg atattagtca
    12361 gcaaacggat cataccaatt aggaaaccga caatcatggc agtttcaccg gctttcggag
    12421 tgattttctt ggagaatata ccaagtgcaa atacggctac cattgcaggt gcaaggagag
    12481 actgtatacc ttgcagatag tcgtaaaggc tgccgagact catcattaca ggaatccatg
    12541 ccatgccgag gataactaca actacggtag cgatacgtcc taccataaca taagtagctt
    12601 cacttttgtt cttaaacatg ggtttgtaaa agtcttctgt aaaaagtgtg gcacatgaat
    12661 taaagaaagc agccagtgaa gcaaccaatg cacagatgaa tccaatagtt acaatacctt
    12721 ttacaccggc aggcagaaca tcctttacca ttacagcaaa agctgcatct gtatttgaca
    12781 tatcaaattc accttttgca gccaaggcgg cagctaccat ccc
//
