LOCUS       c00031_gnlPro..        16304 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NALLKCNB_31.
ACCESSION   c00031_gnlPro..
VERSION     c00031_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 19:49:32
            Original ID  :: gnl|Prokka|NALLKCNB_31
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16304
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16304
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3345:6304]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3346..6304
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16304
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16304
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(263..760)
                     /locus_tag="ctg31_1"
                     /transl_table=11
                     /translation="MSVYKSKFQPVMERWSLVLKIVLLTTGLMFLLRTFMLQSLQDQIA
                     SLLFGAILVSIYIYMLIVIPSFICLEKDQLVIKRVFGKKCIPYSCIKNAFVYDGVQNDV
                     RYFGSNGFLGYIGVMGSTHYGKYYSYVKNPNQQIFILTEKKNYLLSCENRDMFIKDLLI
                     HL"
     CDS             complement(760..1551)
                     /locus_tag="ctg31_2"
                     /transl_table=11
                     /translation="MKSKILTLGVGAAIAATSFSSCDNSNDFPNLAIASEENFVDDETT
                     AISMKKLSQEEQVYIHDMSLLSHNILNDTNAAEAFLNAPLEYARSLGIKSSIDTDDGTV
                     RFLLAICKPEFREAVIKRDIRRFVELCEKYDIFKNANSSNIKLLNHTAITRSKNCVDVQ
                     MGFFWIGEWILLGVAYVGAGIDYAALGGPVVCASRTINSEMALQVWDVETQDGSVYELA
                     DEYKNHYVQDLVKLVKEKRPEVMERYTDKELIEIIQKTLAI"
     CDS             complement(1541..2473)
                     /locus_tag="ctg31_3"
                     /transl_table=11
                     /translation="MSFKQMETYISECVKAFPTIRLVVFSGGECFSLKDDLYQAIYYAH
                     KKGLITRVVTNGYWAVSYEKALGILVLLKELGLNELNLSTGDDHQKWVPFDNIVNAIRA
                     AAKVDLPCLVNIETNPSSQFSEEDFKNHEELKEYIRDNKVIFSSGIWIPFDMEDKIKRD
                     TNYNELIKHRYVQRPIISHGCNSLFESIPIDPEGNVYACCGLACRKAKLLKIGNMNTAG
                     INKIYTRQFDDFLKVWAYVDGPKFILNKIAMETGKNIEVNADMHNCEACLLLLNDPSKI
                     EYIKNNISRYISEVVLKYNIKQKKANYEK"
     CDS             complement(2867..3133)
                     /locus_tag="ctg31_4"
                     /transl_table=11
                     /translation="LQRFKRKALLNRSSGEVAEWSIAAVLKTVVLRGTRGSNPCLSAIN
                     IDNQLFTRITPNFTPRKVKLGVLYYLRFVSCCSVFNYSNWRLF"
     CDS             3346..5574
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg31_5"
                     /sec_met_domain="Gly_radical (E-value: 3.3e-46, bitscore:
                     148.8, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1167.1, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFKDGLWSKEINVRDFVSNNITPYEGDASFLQGPTERTKA
                     VWNHCLKALEEERNNNGIRALDYTTVSTITSHPAGYIDKENELIVGLQTDQVLKRAIKP
                     FGGINVVMKACRENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGLDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKEIK
                     VLGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSQ
                     GTITETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESIGGRFNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNMTVLWSPELPEGFKAFCAQVSIDTSSVQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKDIPVLTGETL
                     KFEEVMANYKKVLIQIARVYNEAMNIIHYMHDKYYYEKAQMAFVDTDPRINLAYGVAGL
                     SIAIDSLSAIKYAHVKARRNDIGLTEGFDIEGAFPCFGNDDDRVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGIAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATQEDRIDNLVTMMDGYFTKGAHHLNVNVLN
                     REMLQDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             5579..6304
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.3;
                     E-value: 1.6e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg31_6"
                     /sec_met_domain="Radical_SAM (E-value: 4.5e-30, bitscore:
                     97.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIEAKGG
                     TATDPEEIVRMAVSQKAFFGKKGGITFSGGEPTFQAKSLIPLFKRLKEAGIHICLDTNG
                     GLWNNDVEELLELTDLVLLDIKEFNPEHHQSLTGRSNEQTLKTAAWLETNHKPFWLRYV
                     LVPGYSDFEDDIRQLGEHLGTYQMIQRVEILPYHTLGVHKYEAMNKEYMLKGVKENTPE
                     QIEKAEKLFRQYFQTVQVN"
     CDS             complement(6537..7799)
                     /locus_tag="ctg31_7"
                     /transl_table=11
                     /translation="MMKEDEKWIKAFKDKLEDYSEPMPASGWERLERELMPVTEKRIYP
                     YRRWAVAAAAVVLVLTTAVSLYFLNSPVADEIRYATAPSLAVNPDVLPEPALPDVQVAV
                     SEPVKPVGTTSINPVSGYLAKNTDPVIVPEVSSLVEKRPEAVTEEKRSEPQQEAIAAIE
                     KKESATAQPPKRKEARRPSGKDKYQLPIGDSSAKRGGKWSMGVGIGNGGGLPTNGSENF
                     APRPMTNRVDLMTIMNGAVSIPADQEVIFEEGVPYLKSNTTAVVDYEHHQPVSFGLSVR
                     KSLPKGFSVETGLTYTLLSSDIKRQGDTKMQSQKLHYIGIPVRGNWNFLEKKYFTLYVS
                     AGGMVEKCVYGKLADDKVNVKPLQFSVAGAVGAQFNATDHVGLYVEPGVSYFFDDGSKV
                     QTIRKERPCNFNLQAGLRFTY"
     CDS             complement(7851..8399)
                     /locus_tag="ctg31_8"
                     /transl_table=11
                     /translation="MNELELSERCRQGDNRARKELYEQYAGRMLGVCLRYAGDRDMAQD
                     LVHDGFLKIFDSFDKFTWRGEGSLRAWMERVMVNTALQFLRKNDVMNQTTALDEVPETY
                     EEPDASAVEVIPQKVLMQFINELPAGYRTVFNLYTFEDKSHKEIAQMLGINEKSSASQL
                     FRAKSVLAKKVKEWLVTNG"
     CDS             8587..9339
                     /locus_tag="ctg31_9"
                     /transl_table=11
                     /translation="MKKFNLITFAVILMLLPILQSCLDDANNDEWVTCPPGGILAIGTM
                     KIPNADTPRDFFIALDNGDNVLPADTADIRNRKYTVAEGQRVFVGYLQMGEEKPGYENG
                     KIFTIEDILTKEIIPLTEATADSIGDDRINVTAHALTKDYLTIEYQYLGSMNENKKHML
                     NLVQNEITGPIKDDGYIYLEFRHNAFNDSPNQLGSSLVSFKLDSIAEQLATAKGIKLRV
                     NTIYDNIQYVTIDINEDKNLKIKSFHSQ"
     CDS             complement(9444..10442)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     -3.5; E-value: 38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg31_10"
                     /sec_met_domain="LysR_substrate (E-value: 1.6e-46,
                     bitscore: 150.8, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 1.6e-17, bitscore: 55.9,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRVKLKISIFALIDSISLINQRTMTIQQLEYILAVDQFRHFAKA
                     AEYCRVTQPTLSAMIQKLEDELGVKLFDRSMTPVCPTTIGKKVLEQARKILSEVICVKE
                     IISEEQHSLSGTFRLAVLPTIAPYLLPRFFPQLMEKYPDLDIRVMEMKTPDIRKALLTG
                     EADAAIIASMLDDAALTEETLFYEQFLGYVSKKEPLFKHDVIRTSDVTGERLWLLDEGH
                     CFRDQLVRFCQMEAVKISQMAYRLGSMETFMHMVESGKGITFIPELAVMQLSEEQKELV
                     RPFAIPRPTRQIVLVTRKDFIRTSLLQVLKEEIQAAVPKEMLTLQAVQCLV"
     CDS             10512..10985
                     /locus_tag="ctg31_11"
                     /transl_table=11
                     /translation="MKTLNYTHLEEKGANTIVLSLQQLLADFQIHYANLRGFHWNIKGH
                     GFFVLHSKFEDLYNGAAEKVDEIAERILMLGGTPANKYSDYLKMAQIKEVDGVNKADDA
                     LNHILETYGHLIAEERKILSLASSHNDEVTVAMMSDYLKEQEKMVWMLTAYNG"
     CDS             complement(11089..12087)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_130"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg31_12"
                     /sec_met_domain="Glyco_hydro_130 (E-value: 2.1e-69,
                     bitscore: 226.4, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEIKIAGAALPAMPWEERPAGCKDVVWRCSANPIIPRDLLPTSN
                     SIFNSAVVPFKDGYAGVFRCDDTNRRMRLHVGFSKDAVHWDINEEPLKFQCDDAEVGTW
                     VYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTYDFVTFHQLENAFIPFNRNGVLFPRK
                     INGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAPFEDSAWQCTKIGAGP
                     IPIETSEGWLLIYHGVLASCNGFVYSFGSALLDIDQPWKVKFRSGPYLISPQKDYECMG
                     DVPNVCFPCAALHDSETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII"
     CDS             complement(12142..13410)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg31_13"
                     /sec_met_domain="MFS_1 (E-value: 5.8e-11, bitscore: 34.4,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKPISPVCWVPTVYFAMGLPFVALSMVSVLMFSDMEVSNAQIA
                     FWTSLIMLPWTLKPLWSPFLEMFKTKKYFVVATEIITGLAFALVALSLPLPDFFRYAIA
                     LMGIIALSGATHDIAGDGVYLTELTATQQAKYIGWQGAFYNLAKILANGGLVWLAGMLK
                     DEFGVVHAWMIVMLMCAGIMILIGLYHIRILPSGGGASGEVNTMSDALNMLWEVIRSFF
                     QKKHIAFYIVFIILYRFAEGYAIKIVPLFLKASVADGGLGLSTQDIGLVYGTFGAGAFI
                     LGSLLAGYYISAFGLRKTLFSLCCAFNIPFLVYFLLALYQPSDLWIIGMAIVSEYLGYG
                     FGFVGLMLFMMQQVAPGKHQMAHYAFATGIMNLGVMLPGMMSGYLSDWLGYRDFFIWVL
                     IATIPAFIVTWLVPFTYPDGKKK"
     CDS             complement(13660..14673)
                     /locus_tag="ctg31_14"
                     /transl_table=11
                     /translation="MNRHLNFVTLICLITGFVSLASCSNDDDEMDKYQKIYIRTGVAPG
                     AEMGAAVVVDCVSNSSTADCSDFEIQLCAVQPVTRDATAALGVDTLKVDTYNSANKTKC
                     KLLPQDNYTIETSEVVLKTGQTVADSSFQVVLKNIEKLTNPGGYVLPVTLKGVTGMDEQ
                     AVSTSMKTVYIRIYTSVLYTSYTKPGNWSAVDRSAWSVSCSNVYADDDAKYGAHLAIDG
                     EINTTWFTWGVANAGECWWNTVLDRPVTLTGFSVTKQSAYGSGYNLRSAEIKVRKEGET
                     EWVTYPRVLTFRNFKGADPQYAAIEPPIPNVKEFRINCLTPDNYTGFAEINLYVKQ"
     CDS             complement(14696..15832)
                     /locus_tag="ctg31_15"
                     /transl_table=11
                     /translation="MKRITIKQCLLACFVLPMILAGCNNADYQVIDNAIYLNEASENGS
                     AKVTVDPENVTTTTLTVRVGQPVTENVTAVLTVDPSILKEYNEANETSYEVLPEQYFTY
                     DKEIKIAAGDVSAIPSEFRVKPYSNENGELYAIPVSLTEIQGPVSTIGLSSKFIILLDK
                     PLIQSVPFMNTTNAVKPSKDELWGVTTNEWSLEAWVQMDGFDINNQAIFNSGSSDHEVY
                     IRFGDAMIPYNSLQVKTLGSQVNTVTLFEKNKWYHLAFVYNSSGLLSIYINGVLDVTLQ
                     TKGGPVRFDKMNMVSSGSYFRNNCQMAQVRLWKSAISQTQIQSNMYFAVKPADPNLIGY
                     WKMDEGKGNAFADCTGHGYDLVAGGTLVWKEHVRFDKQ"
ORIGIN
        1 taagcaacca aagacagtgc aaagcccaac aagtaataaa agaacaaagt attaaataaa
       61 gcaaaaacac ccaattttac tttttagggt ataaaattgg gtattactct tgtaattcac
      121 agattttcaa catttattgc agagatacgg ggtttaatta ttaatgctct aaaaaactaa
      181 cgggaagaat aaaaaacata ttcttcccgt caagtaatac tataactata ttttccaaca
      241 ggttatatta atatccagca tattataagt gaatcaacaa atcttttata aacatatctc
      301 tgttctcaca gcttaagagg taattctttt tttctgttaa tataaaaatt tgttgattgg
      361 gattctttac ataggaataa tattttccat aatgggtact gcccattaca cctatatacc
      421 ccaaaaagcc attacttccg aaataacgga catcattttg aacaccgtca taaacaaaag
      481 cgttcttaat acaagaatac ggaatacatt tcttaccaaa cactcttttt ataacgagtt
      541 gatccttttc caaacatata aatgaaggaa tcactatcag catgtatatg tatatagata
      601 caagaatggc accaaataac aggcttgcga tttgatcctg caaagattgt agcataaaag
      661 ttcttaatag aaacataagg ccagtagtta ataagacaat ctttaatacc agagaccaac
      721 gctccattac cggctgaaat tttgatttat atacgctcat tatattgcta atgtcttctg
      781 tattatttca ataagttctt tatccgtata tcgttccata acctcaggac gtttttcttt
      841 tactaactta accaaatctt gaacatagtg atttttgtac tcatctgcta actcatatac
      901 acttccgtcc tgtgtttcaa cgtcccaaac ctgcaatgcc atttcactgt taattgttct
      961 ggaagcacat actacgggac caccaagtgc tgcataatca attcctgccc caacatatgc
     1021 aacacctaac aaaatccatt caccgatcca aaagaatccc atttgcacat ctacacagtt
     1081 tttacttctt gttattgcag tatggttcaa taatttaata ttggaagaat tggcattttt
     1141 aaaaatatca tacttttcac ataattctac aaatcttcta atatctctct ttattacagc
     1201 ctctcgaaat tccggcttac aaattgctaa taaaaaacgt acagtaccgt catcagtatc
     1261 tatagagctt tttattccca aagaccgggc atattccaaa ggggcattca aaaaggcttc
     1321 cgctgcattt gtatcattta aaatattatg tgataataaa ctcatatcgt gaatatacac
     1381 ctgttcctcc tgtgataact ttttcataga aatagcagta gtttcatcat ctacaaaatt
     1441 ttcttctgac gcaatagcta aattaggaaa atcatttgaa ttatcacatg aagaaaatga
     1501 agtagcagct attgctgccc caacacctaa agttaaaatt ttacttttca tagttcgctt
     1561 tcttttgttt aatattatac tttaatacaa cctcagatat atatctggat atattgtttt
     1621 taatatactc tattttagag ggatcattca acagcaatag acaggcttca caattatgca
     1681 tatcagcatt aacctcaata tttttcccgg tttccattgc tattttattt aatataaatt
     1741 tcggcccatc aacataagcc catactttta aaaaatcatc aaattgtctt gtatatattt
     1801 tatttatacc ggcagtattc atatttccaa tttttaaaag cttagctttt ctacaagcca
     1861 gtccacaaca agcatacaca ttcccttccg gatcaatagg aatactctca aatagactgt
     1921 tgcacccatg ggatattata ggtctctgca catatctatg ttttattaat tcattataat
     1981 ttgtatcacg tttaatttta tcctccatat caaatggaat ccatatacca gaagaaaaga
     2041 taactttatt atcccgtata tactctttta actcttcatg atttttgaaa tcttcctcag
     2101 aaaactgtga acttggattc gtttctatat tcaccaaaca aggcaaatcc actttagctg
     2161 ctgctcttat agcatttacg atattatcaa agggcaccca tttttgatga tcatcccccg
     2221 tgcttaaatt taattcattt aaccccaact cctttagtaa caccaaaatt ccaagagcct
     2281 tttcataact aacagcccaa tacccattag taacaaccct tgttataagc ccctttttat
     2341 gtgcataata aatagcttga tataaatcat cttttaagga aaaacattct ccaccactaa
     2401 agacaaccag cctaatcgta gggaaagctt ttacacattc cgatatatag gtttccattt
     2461 gtttaaatga cattctcccc ctacgttctt agttacactc aaaacaacaa ttcttacacg
     2521 ctgccgtaca ataataagtt gtcaacaatg ataaggtatt aggtgatata aaattcagta
     2581 attccatggc taattattca cttaagagtt taaactcttt caaaatatta cttatatggc
     2641 aaatatactt tatttttgtt acagccaaac ggttaaacac gaaattttaa tctaattata
     2701 caattttatc aatgtgaata acaacttaca aaattataat tttattagat tagaaaggaa
     2761 gtagcattca tagccctcac attctacatt tgtagaaaca gattcaatca aaacaaaaga
     2821 tatataatta ttagccctct atagacacac tgcataagca ggaaatttag aatagcctcc
     2881 agttggaata attaaatacg gaacagcaag aaacaaatct taaataatac aaaacaccca
     2941 attttacttt tctgggtgta aaattgggtg ttattcttgt aaacaactga ttatcaatgt
     3001 ttattgcgga gagacaggga ttcgaacccc gggtacctcg cagtacaacg gttttcaaga
     3061 ccgccgcaat cgaccactct gccacctctc cagaactacg gttaagtagt gcttttctct
     3121 taaagcgctg caaaggtacg aatcattttt taacttgcaa attattccgc aaaaaaatat
     3181 tagaaaagta tatttggaag taataactgc tatctagctt ctccccataa ataggtattt
     3241 ttatgctatt caacataaaa taggaccctt ttatatacct aaaccgaaaa aaggttgtaa
     3301 atttgcgcgc tctaaaggat aactaaccac taactgatta attttatgga actgaataag
     3361 acctttaaag atggactttg gagcaaagaa atcaatgtaa gggatttcgt tagtaacaac
     3421 atcactcctt atgaagggga tgcttctttc ctgcaaggac ctaccgaacg caccaaagct
     3481 gtctggaatc actgtctcaa agctctcgaa gaagagagaa acaataatgg tattcgtgca
     3541 ctcgactaca caactgtatc tactataacc tctcaccctg ccggctacat cgataaagaa
     3601 aacgaactga tcgtcggact acagaccgat caggtgttaa aacgtgccat caaaccgttt
     3661 ggcggaatca atgtggttat gaaagcttgc cgtgaaaacg gagtggaagt agatgacaga
     3721 gttaaggata tcttcactca ctatcgcaag actcacaatg atggggtatt cgatgtgtat
     3781 accgaagaaa ttcgttcgtt ccgttcattg ggattcctta ccggacttcc cgacaactat
     3841 gcacgcggac gtatcatcgg tgattatcgc cgcctggctc tctatggtct tgaccgtctg
     3901 atagaagcta aaaaagaaga tctgcataat ctgacaggtc ctatgactga agcccgcatt
     3961 cgtcttcgcg aagaagtagc cgagcaaatc aaggccctga aagagattaa agtattgggc
     4021 gaatattatg gtttggatct gagccgaccg gcatataccg cacaggaagc tgtacaatgg
     4081 gtgtatatgg cttatctggc tgccgtaaaa gagcaggatg gtgctgccat gtcactgggt
     4141 aatgtatctt cattcctcga catctatctt gaatatgaat taagccaggg tacgataacc
     4201 gaaacattcg ctcaggaact gatcgaccaa ttcgttatca aactccgtat ggtacgccac
     4261 ttgcgtatgc agtcgtacaa cgatattttt gcgggtgatc ccacatgggt gaccgaatct
     4321 atcggtggac gtttcaatga cggacgtacc aaagttacta aaacttcttt ccgcttcttg
     4381 cagacacttt ataacttagg cccgtcaccg gaacctaaca tgactgtact atggagccct
     4441 gagttacccg aaggtttcaa agcattctgt gcacaagtat ctatcgacac ttcttccgta
     4501 caatacgaaa acgacgacct aatgcgtgaa gtccgtcaat cggatgacta cggaatcgct
     4561 tgttgtgttt catatcagga aatcggaaag cagattcaat tcttcggcgc acgtgccaac
     4621 cttgccaaag ccctgctact ggctatcaac ggaggacgtt gcgaaaatac aggtacagtt
     4681 atggtaaaag acatccctgt attgaccggt gaaacactga agttcgaaga agtaatggcc
     4741 aactataaga aagtattgat acaaattgca cgtgtataca acgaagcaat gaatatcata
     4801 cattacatgc acgataagta ttactacgaa aaggcacaga tggctttcgt ggatactgat
     4861 ccccgcatta acctcgctta tggtgtagcc ggactttcaa tcgccatcga ttcactgtcc
     4921 gccatcaaat atgcacatgt gaaagcccgt cgcaacgaca tcggactgac ggagggattc
     4981 gatatcgaag gtgctttccc ttgtttcggt aatgacgatg accgtgtaga ccacctgggt
     5041 gtggacctgg tatatttctt tagcgaagaa ttaaagaaac tccccgtata taagaatgcc
     5101 cgtcctaccc tttcgctgct gactatcact tcgaacgtaa tgtatggcaa gaagaccggt
     5161 gccactcctg acggacgcgc caaaggcatt gcctttgctc ccggtgccaa ccccatgcac
     5221 ggacgtgata aaaatggtgc aatcgcctca ctgagttctg tagccaagtt gcgttatcgc
     5281 gactcacagg atggtatcag caatacattc tcaatcgttc ccaaatcatt gggagcaaca
     5341 caagaagacc gtatcgacaa tctggtgacc atgatggacg gatattttac aaaaggcgca
     5401 caccacctga acgtaaacgt gctgaaccgg gaaatgttgc aggatgcgat ggaacatccc
     5461 gaaaagtatc cgcaactgac tatccgtgtc tcaggatatg ccgttaattt cgtgaaattg
     5521 agccgcgaac atcagttgga agtaatcagc cgcagtttcc acgaaagaat gtaattgaat
     5581 gataaacgta cactcatacg agtcaatggg aacattcgac gggccgggtc tccggctcgt
     5641 cgttttcctt caagggtgta acttccgttg cctctattgt gccaatccgg acacaattga
     5701 agccaaagga gggacagcaa ccgaccctga ggaaatagtt cgcatggccg tcagtcagaa
     5761 agctttcttc ggtaaaaagg gaggtatcac cttttccggt ggagagccta cttttcaagc
     5821 aaaatcgctt atcccacttt ttaaaagact aaaggaagca ggaatccata tttgccttga
     5881 taccaatggc gggctatgga acaatgatgt agaggaacta ttggaattga ctgatctggt
     5941 tttattagat atcaaagaat ttaatccgga acatcatcag tctttaaccg gaagaagcaa
     6001 cgagcagacc ctgaaaaccg cagcctggct tgaaaccaat cataaaccat tctggttgcg
     6061 atacgtatta gtgcccggct acagtgactt cgaagacgat atccggcagc tgggagagca
     6121 tcttggaacg taccagatga ttcagcgtgt agaaatattg ccttaccaca ccttgggtgt
     6181 tcacaaatat gaagcaatga acaaagaata tatgctgaaa ggagtgaaag agaatactcc
     6241 ggagcagata gaaaaggctg agaaactatt caggcaatat ttccagaccg tacaagtaaa
     6301 ttgacttata taagtgtcga aattcgtatt cgccacagat tacacgaatt tacacagata
     6361 aagattcatt ggcaatcaac agattaagtt cattctgcgg tgaattatga cgactgcact
     6421 tatttataat tttgtaagtc acgatataaa agtctccctg ttcttgcctt aattcattac
     6481 aatacaaggc aagaacaggg agataatgta accggcatat tttttgccat cctactttaa
     6541 taagtgaatc gcaatcctgc ctgcaagtta aagttacaag gcctttcttt tcggatggtt
     6601 tgtactttgg agccatcatc aaagaaatac gaaactcccg gttccacata taggccgaca
     6661 tgatctgtcg cattgaattg cgctcccacg gcaccggcta cagaaaattg caaaggcttc
     6721 acattcacct tatcatccgc caactttcca taaacacact tttcaaccat tcctccggca
     6781 gatacataga gtgtaaaata tttcttttcc agaaaattcc agtttccacg tacaggaata
     6841 cctatataat gcaatttctg actctgcatc ttggtatccc cctgccgttt gatgtcagaa
     6901 gacaacaatg tataagtcaa tcccgtctct acagagaaac ctttgggaag agacttacgt
     6961 acagacagtc cgaagctaac cggctgatga tgttcataat ccaccacggc agttgtattg
     7021 gacttcaggt aagggactcc ttcttcaaat ataacttcct gatcggcagg aatactcaca
     7081 gctccattca tgatcgtcat caagtcgacc ctgttagtca tcggacgggg cgcaaaattt
     7141 tcggaaccat ttgtcggaag tccacctcca ttaccgatac ccactcccat cgaccattta
     7201 ccaccacgtt tagcagaaga gtctccgata ggcaactgat acttgtcttt accggacggt
     7261 cgccgcgctt ctttcctctt tggaggctgc gccgtcgcac tttctttttt ctcgattgca
     7321 gcaattgctt cctgttgcgg ctcagatctc ttttcctccg tcactgcctc cggtcgcttc
     7381 tctaccaggg aggatacctc cggaacaatc accggatcag tattctttgc caaatagccc
     7441 gaaacagggt taatactcgt cgttcctacc ggcttaactg gttcggatac agctacctgt
     7501 acatccggca aggcaggttc cggcaataca tccgggttga cagccagtga aggagccgtt
     7561 gcataacgga tttcatcagc taccggacta ttcagaaaat acaaactgac agcagtcgtt
     7621 agcaccaata ccacagctgc cgcagcaacc gcccaccggc gatacggata tattcgtttt
     7681 tcggttacag gcatcagttc cctttccagt cgttcccaac cggaagcagg catcggctcc
     7741 gaataatctt cgagcttatc cttgaatgct ttaatccatt tttcgtcttc tttcatcatt
     7801 ctatttcatt tttgaaatcc aaggttcacc tcagtatctg taaatacatg tcaaccattg
     7861 gtcaccaacc attctttcac tttctttgcc aatacacttt ttgcgcgaaa aagctgtgag
     7921 gcagaagatt tttcattaat ccccaacatc tgtgcgattt ccttgtgcga cttatcttca
     7981 aaggtgtata aattgaatac ggtacgatat ccggcaggga gttcattaat aaattgcatc
     8041 agcactttct gtggtattac ttcaacagcc gaagcatccg gttcttcata cgtttcggga
     8101 acttcatcca gtgccgtggt ctggttcatc acgtcgttct ttcttaagaa ctgtaaagcc
     8161 gtattcacca ttacacgctc catccatgct ctcagagagc cttcaccccg ccaggtaaac
     8221 ttgtcgaagg agtcgaaaat cttcaggaaa ccgtcgtgta ccaagtcttg tgccatgtct
     8281 ctgtctccgg cataacgaag acagacacca agcatgcgcc ctgcgtactg ctcataaagt
     8341 tctttgcggg cacgattatc tccctgcctg caacgttccg acagctctaa ttcattcatt
     8401 ctcctaaaca cgtgtttacc ttataaatgc agcaaagata gaaatactgc acagagagaa
     8461 caactctttt atcacttttg tttctttaac attttaggat gcaatatttc atcacttcct
     8521 gcattttctc aatacaataa agaataaatc tcaatggata aataggataa aaccaacaag
     8581 aaacttatga agaaatttaa tttaataact tttgccgtca tcctgatgtt attgcccatt
     8641 ttacagtcat gtctggacga tgccaacaac gacgagtggg tcacttgtcc tccgggtgga
     8701 atattggcca tcggcacaat gaagattccc aatgcggaca ctccaaggga ctttttcatt
     8761 gcattggaca atggagacaa tgtacttccg gcagatacgg ccgatatacg caacaggaaa
     8821 tacactgttg cagaaggtca aagagtcttc gttggctatc tgcagatggg agaagagaaa
     8881 cctggatatg agaacggtaa aatattcacg atagaagata tattgacgaa agagatcatc
     8941 ccactgacgg aagctacagc agacagcatt ggagacgacc gtatcaacgt cacagcgcat
     9001 gcacttacga aagattatct gaccatcgaa tatcaatatc tgggcagcat gaatgaaaat
     9061 aaaaaacaca tgctgaactt ggtacaaaac gaaataacag gtcccataaa agatgacgga
     9121 tatatctatc tggagttccg gcataatgcc tttaatgact cccccaatca attgggttcg
     9181 agccttgttt ctttcaagct ggatagtata gccgagcaat tggcgacagc caaaggaata
     9241 aaactccgtg tgaacaccat ttatgacaat atacagtatg tcacaataga tatcaacgaa
     9301 gacaaaaact taaaaataaa atcatttcat tctcaataaa acaacaagaa acacctacac
     9361 aatcaggcaa aacgagtaat aattctgata cataaaagaa ataaggcggc gatgtttgtg
     9421 aaaatatcgc cgtcgttttt atattatacc agacactgaa cggcctgcag ggtaagcatc
     9481 tccttgggaa ccgccgcctg aatctcctct ttcaaaacct gcagcagact ggtgcggatg
     9541 aagtctttcc gggtcaccag gacaatctga cgggtaggcc gcgggatagc aaacggacgg
     9601 accagttctt tctgctcttc gctcaattgc atcactgcca gttcaggaat aaacgtaatc
     9661 cccttaccac tctccaccat atgcataaag gtttccatac tacccagccg atacgccatt
     9721 tggctgatct taaccgcttc catctgacaa aaacgaacca actgatcgcg gaagcaatgc
     9781 ccttcgtcaa gaagccaaag ccgttcccct gtcacatcgg acgtacgaat cacatcgtgc
     9841 ttgaacaacg gttccttctt tgagacatag cccaggaatt gctcgtagaa taaggtctct
     9901 tccgttaatg cggcatcatc cagcatgctg gcaatgatag cagcatccgc ttcaccggtc
     9961 agcagagcct tgcgaatgtc gggcgtcttc atctccatca cccgtatatc aagatccggg
    10021 tatttctcca tcagttgcgg aaagaaacgg ggcagaagat aaggtgcaat cgtcggtaac
    10081 actgccaatc ggaatgtacc cgacagggag tgctgttctt cgctgatgat ctccttgaca
    10141 cagataactt ccgaaagaat cttacgggcc tgttccagca ctttcttacc aatggtagta
    10201 gggcaaaccg gtgtcatgct acggtcgaac agtttcaccc ccaattcgtc ttccagcttt
    10261 tggatcattg cactcaaagt aggttgcgtc acccggcaat actcggcagc tttagcaaaa
    10321 tgccggaact ggtccacagc cagaatatat tccaattgtt gtatagtcat cgttctctga
    10381 tttattaaag atatagaatc tatcaatgca aagatagaaa ttttcagttt gacacgaatc
    10441 attttgtgcc gtatctttgt tccagataaa aagaagaaat atagtattaa ctcaaaaaaa
    10501 acaatatcat tatgaagact ttaaattata cacatttgga agaaaaagga gctaacacca
    10561 tcgtactgtc attacagcaa ctgcttgccg attttcagat tcattatgca aacctgagag
    10621 gatttcactg gaacatcaaa ggacacggtt tcttcgtact gcacagcaag tttgaagatt
    10681 tatataatgg agccgccgaa aaggtggacg aaatagccga acgtatactg atgctgggag
    10741 gaactcccgc caataaatac agtgactatc tgaagatggc gcagatcaag gaagtggacg
    10801 gagtgaataa ggccgacgac gctctgaatc atattctcga aacttacggg catctgattg
    10861 cggaagaacg taaaatcctg tctctcgcct cttcacacaa cgacgaagta acagtggcca
    10921 tgatgagcga ctacctgaaa gaacaggaaa agatggtttg gatgctgact gcatacaacg
    10981 gataacagcc gaaagggtgt agccatctga ccgaaaaggt gtagccatac aaacaaaagg
    11041 gtgtagccat cccggcggga tagctacacc cttcctgttt tattcgattc agatgatact
    11101 tgtacgtttg gtaaattcaa taatctccgg aatgtatccg aatgcgagcc cggtcactgt
    11161 atccgcacac ccataataga tggcaatccg tccggtctcc gaatcatgaa gcgccgcgca
    11221 tgggaaacag acattaggca catcacccat acattcgtaa tccttctgag gtgaaatcag
    11281 ataaggcccc gaacggaatt ttactttcca gggctgatcg atgtcaagca gtgccgaacc
    11341 aaaactatac acaaaaccgt tgcaggaagc caatacacca tgatagatca gcaaccagcc
    11401 ttccgaggtt tcaatcggga taggccctgc accgatcttg gtacactgcc aggcactgtc
    11461 ttcgaacgga gccggcgaca taacatgacg atgacgtccc caaaactcca tatcgggaga
    11521 ctcgctatag aaaatatctc caaaaggagt atgcccatta tcactcgggc ggctcaacat
    11581 cgcaaaacga ccgtttatct tacgagggaa caagactcca ttccgattga agggaataaa
    11641 ggcattctcc aactggtgaa aagtaacaaa atcataggtg taggccacac cgatagtagg
    11701 accatgatag ccattacacc aggtcacata gtagcggtct tcgataaagc aaacccgtgg
    11761 gtcatatcca tagacccagg ttccaacctc agcatcatca cattgaaact ttaacggttc
    11821 ttcgttgata tcccaatgaa cagcatcctt gctgaatccc acatgcaaac gcatgcgacg
    11881 attagtatca tcacaacgga acacccctgc atagccatcc ttaaacggaa ctacggcact
    11941 gttgaatata ctgtttgaag tagggagcaa gtcgcgcgga ataatcggat tggccgaaca
    12001 acgccacact acatctttac atcctgccgg acgttcttcc caaggcatag ccggcaaagc
    12061 agcacctgca attttaattt cttccatgat tcgattaaat taatattatg tatatatctt
    12121 gtttatattg aaaatctctt tttatttctt ctttccgtcc ggatatgtga aaggtaccag
    12181 ccaagtcacg ataaaagccg gtatggtagc gataagtacc cagataaaga aatcgcgata
    12241 acccagccaa tcgctcaggt atccgctcat cattccggga agcatcaccc ccagattcat
    12301 aataccggta gcaaaagcat aatgtgccat ctgatgtttg ccgggagcca cttgctgcat
    12361 cataaagagc atcaatccga caaaaccaaa cccgtaaccc aagtattcag acacaatggc
    12421 cataccaata atccatagat cggaaggctg gtaaagggct aacaggaaat ataccaagaa
    12481 cggaatatta aaagcgcaac ataaagaaaa caaagtcttc cgaagtccga aagccgaaat
    12541 gtaataaccg gccaaaagcg aaccgagaat aaaagctccc gctccgaacg taccatatac
    12601 cagtccgata tcctgagtgc tgagtcccaa tccaccatcc gcaaccgacg ctttcaggaa
    12661 caacggtaca atcttgatgg catatccttc ggcaaaccgg tacaaaatga taaagacaat
    12721 gtagaaagca atatgttttt tttggaaaaa agagcggatg acttcccaaa gcatattcaa
    12781 tgcgtcactc atcgtattca cttcaccgga agctcctcct cccgaaggca aaatccggat
    12841 gtggtaaaga ccgatcagaa tcataatacc cgcacacatc aacatgacaa tcatccaggc
    12901 atgtaccact ccaaattcat ccttcagcat acctgccagc caaaccaagc ctccgttggc
    12961 aagtatcttg gctagattat aaaaagctcc ctgccaaccg atatacttgg cttgctgggt
    13021 agcagtcagt tcagtcaggt atactccgtc acccgcaatg tcatgagtcg caccactgag
    13081 agcaatgatc cccatcagag cgatggcata acgaaaaaag tcgggcagcg gcagcgaaag
    13141 tgctaccaat gcaaatgcca gtccggtaat gatttccgta gcgacaacaa agtatttttt
    13201 cgttttaaac atttccagaa acggactcca taaaggcttc aatgtccagg gaagcataat
    13261 gagagaagtc cagaaagcaa tctgtgcatt cgacacttcc atatcggaaa acataaggac
    13321 agaaaccatc gaaagggcca caaacggcaa tcccatagca aagtaaacag taggcaccca
    13381 acatacaggg cttatcggct ttttattcat cagttagttt tttataataa ttccatcggt
    13441 taacaattcc agtaagcaaa gataggggat attaaaaaca taacccaaga ttacgacaag
    13501 aagttgcttt cattatttaa taatacaact cacccgggaa aactactaac ctctatcacc
    13561 ctttttttat taaactttat caatacgaca cacgcaaaga agcaccgaag actttcatcc
    13621 ccgatgcctc tcgccccctt atctacaatc taaacacctc tattgcttca catataaatt
    13681 tatctcagca aacccggtat aattatccgg agtcagacag tttattctga attcctttac
    13741 attcgggata ggtggttcga tggccgcata ttgcggatca gcccctttaa aatttctgaa
    13801 agtcaagact ctcgggtaag taacccactc ggtttcaccc tctttccgaa ccttaatctc
    13861 agcacttctc agattataac ccgatccgta ggcactctgt ttagtgaccg aaaatccggt
    13921 taaggtaaca ggccggtcca gtaccgtatt ccaccaacac tctccggcat tagccactcc
    13981 ccatgtaaac caagtagtat ttatctcacc gtcaatagcc agatgtgcac catatttggc
    14041 atcatcatcg gcataaacat tgctgcaact tacactccac gcacttcgat ctacagcgga
    14101 ccaattcccg ggtttcgtat aactggtata aagcacgctg gtataaatcc ggatataaac
    14161 cgtcttcata gatgtactga cagcctgttc gtccatgccc gtaactcctt taagcgtcac
    14221 gggaagcaca tatccgccag gattagtcaa cttttctata ttcttcaaaa cgacctgaaa
    14281 agatgaatcg gccactgtct gtcccgtttt taagacaact tcacttgttt caatggtata
    14341 attatcttgg ggcaacaact tacatttcgt cttattggca gaattgtaag tatccacttt
    14401 cagcgtatct actcccaaag cggcagtggc atcccgcgta accggctgta cggcacacaa
    14461 ttgtatttca aaatcagaac agtcggcagt agaggaattg ctcacacaat ccaccactac
    14521 cgcagcaccc atttcggccc ccggtgcaac tcccgttctg atatatatct tttgatattt
    14581 gtccatttca tcatcatcgt tgctgcacga agccaacgat acaaagcctg ttatcaggca
    14641 gattaaggtc acaaaattca aatgtctatt catatcttat cttcttttta catagttatt
    14701 gcttatcaaa acgaacatgc tctttccaga caagagttcc tcctgccacc aaatcgtatc
    14761 cgtgtccggt acagtcggca aaggcatttc ctttaccttc atccattttc caatagccta
    14821 tcaggttcgg atcggcgggt ttcacggcaa aatacatgtt ggactgaatt tgcgtctggc
    14881 tgattgcgct cttccaaaga cgcacctggg ccatctgaca attgttgcgg aagtagctac
    14941 cgctcgaaac catgttcatc ttgtcgaatc taaccgggcc accctttgtc tgcagagtca
    15001 cgtcgagcac tccgttgata taaatcgaca ataacccgga agaattataa acgaaggcca
    15061 gatgatacca cttattcttc tcaaacaaag tcaccgtatt gacctgactt ccaagtgtct
    15121 tcacctgtaa tgaattataa gggatcatag cgtcaccgaa acggatataa acctcgtggt
    15181 cgctgctgcc cgaattaaat atagcctgat tattaatatc gaatccgtcc atctgtaccc
    15241 aagcctcgag tgaccattca ttggttgtca ctccccacaa ttcgtccttg gagggcttca
    15301 cggcattggt cgtattcata aacggtacag actgtatcag cggcttatcc agcaaaatga
    15361 taaacttcga cgaaagcccg attgtggaca ccggtccctg aatttctgtg agagataccg
    15421 gaatagcata caattctccg ttttcgtttg aataaggttt cactctaaac tcactgggga
    15481 ttgcgctaac atcgcctgcc gctatcttta tctctttgtc ataagtaaaa tactgctcgg
    15541 gaaggacttc gtacgaagtt tcattagctt cattgtactc tttaagaata gaaggatcta
    15601 ccgtcaggac agcagtcaca ttttcggtta caggctgtcc cacacgtacg gtcagagtag
    15661 ttgttgttac attttcagga tcaacggtaa cctttgccga accattctcg gatgcttcat
    15721 tcaaataaat cgcattgtcg ataacctggt aatcggcatt gttgcatcct gccaggatca
    15781 tcggcagaac gaaacaggca agcaaacatt gttttattgt tattcttttc ataatcaaat
    15841 tctttaaagt cattttacag caggattcat tattctgatt gcttcacgca ggtacttata
    15901 ttcgatgtcg cccggatagt catattccat gtgataggtg cctactccac ccttccgtac
    15961 ctgttttccg tcaatagtcg gagtccagcg tgccatgccg gcaagtgctc tcattttgtt
    16021 tccgtaacga tctacataat cacctcctcc tgtcggagca taagattcga aattctccgt
    16081 aacgatgtac atattagcca ctttctccgg aggaagtatt cctttaaagt tggcaatcgt
    16141 accagccaga cgtctgtcaa gattagcatc ggaattaccc gcaaggttag agtatgcctg
    16201 cacaatgaaa tagtcaaagt aaggcccggt ttccggatga atactttgag gctcgccatc
    16261 aatcacaagt aaccgtcccg tacctgattt aggtccgatt cttt
//
