LOCUS       c00023_gnlPro..        13495 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HIOFPGIA_23.
ACCESSION   c00023_gnlPro..
VERSION     c00023_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 00:18:29
            Original ID  :: gnl|Prokka|HIOFPGIA_23
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 204532
            Orig. end    :: 218027
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13495
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[214532:218025]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13493
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13495
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13495
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             788..2362
                     /locus_tag="ctg23_139"
                     /transl_table=11
                     /translation="MRKNRIRILSMVVFSLCLPFSLFAQIDKDMKEFDDFVKQQQKEFD
                     DFVSEQNKEFAEFLKETWKEYDLQKPVARPQRPEPVKPVSFDHKKPATKPQEVKVGEVT
                     RLPIPTVTPSATFSPSKGKTQIPVVPGGKDVAVEPEKDFAVLPEIKPEVKPEETVPAKR
                     SLSGVEFSFYSKDCVVNASLKNRLTLKGIAEKDISAGWETLSRSNYQPLIDDCLAFKKD
                     NALNDYGYLLLTRKVATELCGSTHSDEIALMQMFLLSQSGYRVKVARMDNRLTLFYASG
                     NMIYATCFITLNGVNYYRFDTTPDKTNSIYTYNRDFANAKNPVNMNITAPQPFSGTYVE
                     KTLQAKAYPSVKVCSKVNSGLISFYKDYPQCDFSVYVGAPVSQEVQQTVLPSLQAAVQG
                     KKQSEAANILINFVQTAFDYKTDGDQFGYEKPFFVDELFYYPYSDCEDRAVLYSYLVRT
                     LMGLDVVLLEYPNHMATAVCFDENIDGDYITVSGKKYIICDPTYIGASIGLAMPQFKNV
                     AAKVLKY"
     CDS             2375..3661
                     /locus_tag="ctg23_140"
                     /transl_table=11
                     /translation="MKNIKKYLCAIVMMVISMTAFAQEDVFSGDWLGANKEGDLKVAFT
                     LNCDGNWQLNPYNENARCNGFMEVNMLEPGGRESLMATYEFYVESMNGNELTLSFVGGR
                     PEVDAGISGQCKVVYKDDKLSFSGLDKGGKDAAFNGLTLVKSGSGADAIADAAADDGVP
                     LGVKILAVLQLILYIAVVLFIVGHMFFVWYKGARYKEVFTVEGMLNKRLAAGMPEKMTD
                     EEITEAWKLMDEAFATWTVIEKTDDDEFRKPTKMKQIKKSVLLIDQVIGMCPTDADVIE
                     RLNSLTDVINSGEERHFDGSRKLIWLGVIVGILMYWMMGVGMMFSTLIATGLYVVASRT
                     PQFLIDKRALRGGGNIHNGIFAGVFGLLAGAQTVRTIYKFNDGHKEYSDDHSQHWIALA
                     IGLVVLFVLAMMMAFWALLNYLRNYVLYF"
     CDS             3877..4170
                     /locus_tag="ctg23_141"
                     /transl_table=11
                     /translation="LKTKDEIIAILRNFKEEFGERYGIEKLGLFGSVARGEQKEDSDID
                     ICVKLQDPDYFTRMEIKESLEERFNAKVDVVSLTAIMRSLFRNHIEKDAIYI"
     CDS             4154..4540
                     /locus_tag="ctg23_142"
                     /transl_table=11
                     /translation="MQSISNADILDMLLFVEERINTTIERCGSVISVNDFLASPDKMDI
                     FDATCMRLQTIGETVKNIDNLTNHELLINYAGTPWRSIIGLRNIISHEYLSIDPEEIFK
                     IVKVHLPGLLLAIQQIRNDIAASI"
     CDS             4657..4899
                     /locus_tag="ctg23_143"
                     /transl_table=11
                     /translation="MISLMKFLGGDKISRRKFLATPDHSYFPICIEAMKLGIHVYVEKP
                     PVRTSFFCLLLTLNSQNLQNSFNRFTEPFMPLFLF"
     CDS             4956..6233
                     /locus_tag="ctg23_144"
                     /transl_table=11
                     /translation="MKHGIYILTILMALLSLPESGYASIPFFAVANDTIRRAVIYFDAN
                     EAKVDLSYKNNNQVIIILDSLLLGNLNTKYITALNVETFVSPDGDESYNRSLAARRNDS
                     IKEFLQRYNSDVSVDKIHFFSGGEDWSEFRKLVASDSNLPDREEVLILIDYHKNDVNKR
                     KQLLRKLNRGIAYRYIVHNIFPELRRSVITIVGETSKLGKEAFEPVSSVSGLFVSKQEE
                     ALPKDQPDKPVGESEKKQACEVDISEAEGPVKSQTVLAVKNNLLYDLALAPNIEVEIPI
                     GKRWSLNTEYKCPWWLNSKHDFCYQLLSGGMEGRCWLGNRQKRDRLTGHFIGFYAEGGI
                     YDFQLRGDGYQGKYYGAAGVTYGYARQLARHFSLEFSLGIGYLTTEYKKYTPYEGDIIW
                     TNSGRYNFIGPTKAKVSLVWLITTKR"
     CDS             6291..7238
                     /locus_tag="ctg23_145"
                     /transl_table=11
                     /translation="MLIGCSRRDILDDYPVSGVDIKLDWDGVTDQLPEGVRVIFYPKNG
                     DGRKVDKYLSVRGGEMKVPPGRYSVVVYNYNTESIRIRGEESYETIEAYTGNCNGLGIA
                     GTEKMVWSPDSLYVLNIDELKIEKSEEVLRLDWKLESVVKKYSFAVEAKGLEYVATVVG
                     SIDGLSDCYCIGKGRGVCSSQPIYFEVKKGDSKVTAFFTAFKQVKEMTMPTRMSTSERE
                     TSSEKGAIILILKFIKTDNTVQEATIDVTEIIGTLENAGTGEDGKPTPPPEIELPPDDK
                     IEVDKPDTPSGGGGGIGGDVDGWGPEDNVELPVN"
     CDS             7293..8282
                     /locus_tag="ctg23_146"
                     /transl_table=11
                     /translation="MKKILLAVTAALAITGCSQNEEFENAGQKAEINFGSIVGNSTRAA
                     IMTTDGFETFTVNGYKTSDKMGDAVSLASFMPNEVVTKTDGAWKHANVFYWPSNYVQFF
                     ATSPQQTLSLPSKGYPTFDYTVGGIADQKDLLVANQIDKQKSENAVELKFQHALTQVNF
                     SIKGDTKGFDYKVTNLTISGVDGTGTFKFDGTATVGAWAQDGKAAGTYTATYAEGSEIT
                     LINVTDLAATTKFDANPTASLFMLLPQTLKAGAKVAITYTAAPTGKTDVTDLTFTGTKE
                     VALTGAWIAGQKVRYTLTLSSDAKEITITPTVSEWGTSESDTPLTPSN"
     CDS             8537..9376
                     /locus_tag="ctg23_147"
                     /transl_table=11
                     /translation="MPSICQGTWDCQICPKAVSNAITHVIYQRGFHKPAQKCEENLILF
                     LMKGEILVNSKEYAGTMLKEGEFILQAIGSMFEMLAMTECECIYYRFIQPELFCDFRFN
                     HIMKEVSPPLIYTPLKIIPELQYFLNGSITYLKGDKVCRDLLSLKRKELAFVLGYYYSD
                     YDLSSLVHPLSKYVNSFQYFVIQNYKKVKTVEELAQLGGYTLSTFRRIFNNVFHEPVYE
                     WMLARRKEGILDDLNNSKCSISEICYKYGFESLPHFSNFCKKSFGASPRNLRRQDIS"
     CDS             complement(10001..10756)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_148"
                     /sec_met_domain="Fer4_7 (E-value: 1.1e-11, bitscore: 38.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 7.9e-25, bitscore: 80.3,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.8e-06, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQAGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISERKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIAKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNISISNIARLNRDFIIAKLKD"
     CDS             complement(10793..12772)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 202.6; E-value:
                     3.8e-62)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_149"
                     /sec_met_domain="FAD_binding_2 (E-value: 9.2e-62, bitscore:
                     202.6, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.2e-36,
                     bitscore: 118.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKIDSKIPEGPVAEKWTNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKG
                     GDYRAREANVYRLAEVSNAIIDQCVAQGVPFAREYGGTLDNRSFGGAQVSRTFYAKGQT
                     GQQLLLGAYSALSRQVNVGTVKLYTRYEMQDVVIVDGRARGIIAKNLVTGELERFAAHA
                     VVIATGGYGNAYFLSTNAMGCNCTAAISCYRKGAVFANPAYVQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKKEDAVKLQKGEIKGSDIPEEDRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSEAINRLGIDVVLQRYGNLFDMYEEITDVNPGE
                     LAKEINGVKYYNPMMIYPAIHYTMGGIWVDYELQTTIKGLFAIGECNFSDHGANRLGAS
                     ALMQGLADGYFVLPYTIQNYLADQITVPRFSTDLPEFAEAEKAVQAKIDKFMSIQGKES
                     VDSIHKKLGHVMWEYVGMGRTAEGLKKGIAELKEIRKEFETNLFIPGSKEGMNVELDKA
                     IRLYDFITMGELVAYDALNRNESCGGHFREEYQTEEGEAKRDDENFFYVACWEYQGDDE
                     KAPVLHKEPLVYEAIKVQTRNYKS"
     CDS             complement(12810..13493)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_150"
                     /sec_met_domain="SucD_FumR (E-value: 7.8e-131, bitscore:
                     426.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VGRKVVMSVTGIALVLFLTFHMAMNLVAIISADGYNMICEFLGAN
                     WYALVATAGLAALFVIHIIYAFWLTMQNRKARGSERYAVVDKPKTVEWASQNMLVLGLI
                     VIVGLGLHLFNFWAKMQLPELMHNMGMHADTLTLAYAANGAYHIQQTFSSPVYVVLYLV
                     WLFALWFHLTHGFWSSMQSLGWNNKVWINRWKCISNIYSTIVVLGFALVVVVFFVKTLI
                     CGGAC"
ORIGIN
        1 cttgtatgaa atccgaagct gcaaggatgc ttgctttgca aagagcggct tatctgtatt
       61 cattgcagca aggggtacaa ttgagacttc tctcggacgt tttttccacc atggagactg
      121 ccagtaatac atacgaagac caaagaaaca aaatgcttgt attgggagtg atcgaacatc
      181 ccgttcaaca tgtttcctac cggattgagc atgaatatac ttctatattt ggagagaaat
      241 ttctggaggt atcttttact ccatcgaatg atagttgcga tttttcttat cattccatta
      301 gtgagttgat gcttttgttt acgaaagaaa gggttgagga agaagaggtg aaattcaatt
      361 tattgttgga atcggatagt tgtagggagc aatcagacca gtcatggttt cagcttaagg
      421 gaacacagtc atctcctcaa ataatttcat atatgaacgg agttgaaatt tgttcttcac
      481 aggaaggctg ttggtatgaa gatgccggtt ttggaggtca ggacggattg gagaagatgg
      541 atatgaggaa tgccttttgg aatgcctata tgtcttcttt ggtgaaggca ctgttgttat
      601 atccgttttc tgatgtaaat gtcaagcagg tggacgatcg tttcaatggc ggcactgatt
      661 ccggttgtgg tttgtatcgg gagaaggttg tcgctgtctt gtccatttcc ccctttatca
      721 aagatatacg gaataataag ctgtatgtgg attggcagat aacagaacaa caaaatataa
      781 taaggaaatg aggaaaaata ggatacgaat actatctatg gtagtttttt cattgtgttt
      841 gccgtttagt ctttttgcgc aaatagataa agacatgaag gagtttgacg attttgtgaa
      901 gcagcagcaa aaagagtttg atgattttgt gagcgaacag aataaggaat ttgccgaatt
      961 tctgaaagaa acctggaaag agtatgactt gcagaagccg gtggcacgtc ctcaaaggcc
     1021 ggagcctgta aaaccggtca gctttgacca taagaagccg gcaacaaaac cgcaagaggt
     1081 taaagtaggg gaggtgacac gactccccat tccgacagtg actccaagtg cgacattttc
     1141 tccttcaaag gggaaaacac agattccggt tgtaccggga ggtaaagatg tggctgtaga
     1201 accggaaaag gattttgcgg tgctccctga aataaaaccg gaagtgaagc ctgaagaaac
     1261 cgttccggcc aaacgctcac tttccggtgt agagttttcg ttctatagta aagattgtgt
     1321 tgtcaatgct tcattgaaga accggctcac tttaaaaggg attgcagaga aagatatttc
     1381 tgccggatgg gagacgttat cgcgtagcaa ctatcagcct ttgatagacg actgtctggc
     1441 ttttaaaaag gataatgccc tgaatgacta tggttatctg ctgttgacga ggaaagttgc
     1501 tactgaacta tgtggaagta ctcattccga tgaaatagct cttatgcaaa tgtttctcct
     1561 ttctcaatcg ggatataggg ttaaggtggc gcgtatggat aaccgcctta ctttattcta
     1621 tgcttcgggt aacatgattt atgctacctg ttttataact ttgaatggag taaactatta
     1681 caggtttgat actaccccgg ataaaactaa ttctatttac acttacaacc gtgatttcgc
     1741 caatgcgaag aacccggtaa atatgaatat cactgctcct caaccctttt caggaactta
     1801 cgtggagaaa acgttgcaag cgaaagctta tccatccgtc aaagtctgct cgaaagtaaa
     1861 ttcgggactt atttccttct ataaggatta tccgcaatgt gacttttctg tctatgtggg
     1921 agctcctgtc agtcaggaag tacaacagac ggtgcttcca tcattgcaag ctgccgtaca
     1981 agggaaaaaa caatcggaag ccgctaatat actgattaat ttcgtgcaga cagcttttga
     2041 ttataagaca gatggtgacc agtttggtta tgaaaagcct ttctttgtgg atgagctgtt
     2101 ctactatcct tattccgatt gcgaagaccg tgctgtgtta tactcttatt tggtacgtac
     2161 tcttatgggg cttgatgttg tattgttgga atatcccaat cacatggcaa cagcggtctg
     2221 ttttgatgaa aacattgacg gagattatat aactgtaagc ggaaagaagt acataatttg
     2281 tgatccgact tatattggag cttctatcgg gcttgctatg ccgcaattta agaacgtggc
     2341 agccaaagtg ttgaaatatt aattttatta tattatgaag aatattaaaa agtatttgtg
     2401 tgccattgta atgatggtta tttcgatgac tgcatttgcg caggaagatg tttttagcgg
     2461 tgactggcta ggagcaaata aagaaggcga tttaaaggtt gcgttcacat tgaattgtga
     2521 tggtaattgg caattgaatc cttataatga gaatgccaga tgcaatggat ttatggaagt
     2581 gaatatgctg gaacccggtg gaagggaatc tttgatggca acttatgagt tttacgtcga
     2641 gagtatgaac gggaatgaac tgactctttc ttttgtaggc ggacgtccgg aggttgatgc
     2701 cgggatttcc ggtcaatgca aagtcgttta taaagatgat aagttgtcgt tttccggact
     2761 tgataaaggc ggaaaagatg ctgcctttaa tggattgaca cttgtaaaaa gcggtagtgg
     2821 agctgatgca atagctgatg ctgcggcgga tgacggagtt cctttgggag taaagatatt
     2881 ggctgttctc caactgattt tgtatattgc cgttgtttta tttattgtgg ggcatatgtt
     2941 ttttgtatgg tataagggcg cacgttataa agaggttttt acggtagaag gaatgttgaa
     3001 taaacgcctt gcagccggaa tgccggagaa aatgacggat gaagagataa cggaggcgtg
     3061 gaagctgatg gatgaggcct ttgctacttg gacggtgatt gaaaaaacag atgatgatga
     3121 attcagaaag ccgacaaaga tgaagcaaat taagaaatct gttcttttga ttgatcaggt
     3181 tatcggtatg tgtcctactg atgctgatgt catagaacgc ttaaactcat tgactgatgt
     3241 gattaatagt ggtgaagaac gtcattttga tggttccagg aaattaatct ggttaggtgt
     3301 cattgtgggt atcttgatgt attggatgat gggagtcggt atgatgtttt ctactttaat
     3361 agctaccggt ttgtatgtgg tagcgagcag gacgcctcaa ttcttaattg ataagcgggc
     3421 acttcgtggc ggtggaaata ttcataatgg tatttttgcc ggagtgttcg ggttattggc
     3481 aggagcgcag acagtgcgga caatatacaa gtttaatgat ggtcataaag aatattctga
     3541 tgatcattca caacattgga ttgctttggc aatcggactt gtcgttttgt ttgtattggc
     3601 aatgatgatg gcgttctggg cacttctgaa ctatttacgt aattatgttc tgtacttttg
     3661 atggataaaa ctaacatggt tgttaataat ggattcggca gcataattag gctatttatg
     3721 ttttgaagta gaatttagag tagcaggtgt acaggggatc gatgaaaatt cgatgacctg
     3781 tgcatcttat tttaattagt gatactacaa aatatgatta agaacttgct aattccaata
     3841 taaattttaa tatttgcatt ataacaatag tgtcaattga aaacaaaaga tgaaataatc
     3901 gctattctcc ggaattttaa ggaagaattt ggggagagat atggaattga aaagttggga
     3961 ctttttggtt ctgtggctcg tggtgagcag aaagaggata gtgatattga tatttgtgta
     4021 aagcttcaag atccggatta ttttactcga atggaaataa aagagtcatt agaagagcgt
     4081 tttaatgcaa aagtggatgt cgtgtcttta accgcaatta tgcgtagttt atttcgcaat
     4141 catatagaga aagatgcaat ctatatctaa tgctgacata ttggatatgc ttctttttgt
     4201 agaagaacgt attaatacaa ctatagaaag atgtggtagt gtcatttctg taaatgattt
     4261 cttagcttct cctgataaga tggatatttt tgatgcaact tgtatgcgtt tgcaaaccat
     4321 aggtgaaact gttaagaata tagataacct gactaatcat gaattattga taaattatgc
     4381 cggtactcca tggaggagca tcattggact gcgcaatatt atttctcatg aatatttatc
     4441 tattgacccc gaagaaattt ttaaaatagt aaaagtgcat ctgcctggat tgcttcttgc
     4501 aattcagcag atcaggaatg atattgctgc tagtatatga gacctttgta gcttttctat
     4561 tttttattat gcaaacggta gtctttaggt accactccca tccgctttgt acactcctta
     4621 tagaaatgtg atctattcat aaacccactt tgatacatga tttctttaat gaaatttttg
     4681 ggtggggata aaatatctcg tagaaaattc ctggcgactc ccgatcatag ttatttcccg
     4741 atttgtatag aggcgatgaa gcttggcatc catgtgtatg tggaaaagcc gcctgtcaga
     4801 acttcctttt tctgtttatt attgacctta aactctcaaa acttgcaaaa tagtttcaat
     4861 cgtttcacag aacctttcat gcctttgttt ttattctaaa agtatgattc gatttgtttt
     4921 ctaacttcta tatttgttat cagaaacgaa cgacaatgaa acatggtatc tatatattga
     4981 ctattcttat ggctttatta agccttccag aaagtgggta tgcttcgatt ccatttttcg
     5041 ctgttgcgaa tgatacaatc cggcgggcag tgatatattt tgatgcgaat gaagcgaaag
     5101 tggatcttag ttataagaat aataatcagg taattataat tttagattct ttgcttctcg
     5161 gaaatttaaa tacgaaatat ataacagcgc tgaatgtgga aacttttgtt tctcctgatg
     5221 gtgatgaatc ttataataga agtttggctg ctcggagaaa tgattcgata aaggaattct
     5281 tacaacggta taattcggat gttagtgttg ataagattca ttttttttca gggggagagg
     5341 attggtcgga gtttcgtaag ttggtggcat ccgactctaa cttaccagat cgggaagaag
     5401 tgctgatatt gattgattat cataagaatg atgtcaataa acggaagcaa ctgttgcgaa
     5461 aattgaatcg gggaattgct taccgataca ttgttcacaa tatctttcca gaactgcgga
     5521 gatcggttat tacgattgtc ggagaaactt cgaaattagg taaagaggct tttgaaccgg
     5581 tatcttctgt ctccgggttg tttgtttcaa agcaggaaga ggcgcttccg aaagatcaac
     5641 ctgataagcc tgtgggagaa agtgaaaaaa aacaggcctg tgaggtcgat atatcggagg
     5701 cagaagggcc ggtgaaaagc caaactgtac ttgcagtgaa gaataatctg ttatatgatt
     5761 tggcattggc gccaaatata gaagtggaaa ttccgatagg caagaggtgg tctttgaata
     5821 ctgaatataa atgtccgtgg tggctgaata gcaaacatga tttctgctat cagctccttt
     5881 cgggagggat ggaaggacgt tgttggctgg gaaaccgtca gaagcgtgac cgattgaccg
     5941 gacattttat cggattttat gctgaaggcg ggatatatga cttccagctg cgtggagatg
     6001 gctatcaagg taagtattac ggagctgcgg gagtgactta tggatatgca cggcaattgg
     6061 cacggcattt ttctcttgaa ttcagtcttg gcatagggta tttgacaaca gaatataaaa
     6121 aatatactcc ttatgaggga gatattatat ggacaaatag tgggcgttat aactttattg
     6181 gtcctaccaa ggcgaaagtt tctttggtat ggctgataac aacaaagaga taggagggcg
     6241 caatgcgaaa tacaagatac aggtttcttg tgcttttgtc ctcgctgctg atgttaattg
     6301 gatgtagccg tcgcgatata ttggatgatt atcccgtaag tggggtagat ataaagctgg
     6361 attgggatgg agtgacagat caactgccgg agggagttcg ggtgattttt tatccgaaga
     6421 acggagatgg caggaaagta gataagtacc tttcggtacg aggcggagaa atgaaagttc
     6481 ctccgggacg gtattcggta gtagtctaca actataacac ggaatctata cgaatcaggg
     6541 gtgaagagtc ctatgaaacg atagaagcct acacgggaaa ctgcaacggt ttagggattg
     6601 caggaacgga aaagatggtt tggtcaccgg attcattgta tgtgttgaat atagatgagc
     6661 tgaaaataga gaagagtgaa gaagtgcttc gcttagactg gaagttggaa tctgtggtga
     6721 agaaatattc ttttgcagta gaggctaaag gcttggagta tgttgcaaca gtggtaggaa
     6781 gcattgatgg attatccgat tgttactgta taggcaaagg tcgtggagtg tgtagctcac
     6841 aacctatcta ctttgaggta aagaagggag atagtaaggt aacggcattt ttcaccgctt
     6901 tcaaacaagt aaaggaaatg acaatgccga cgcgaatgtc aacatcagag agagaaactt
     6961 ctagtgagaa aggtgctata atattaatat tgaaatttat caaaacagat aatacagttc
     7021 aggaagcaac aattgatgtt actgaaataa taggtacact tgaaaatgct ggaacagggg
     7081 aagatggaaa gccaacccca ccaccggaga ttgagttacc gcctgatgat aagattgagg
     7141 ttgataagcc ggatacacct tcgggtggag gtggaggtat tggaggagat gttgatggat
     7201 ggggacccga agataatgta gagttacccg tgaattaaaa tagatgctat aaacaaaata
     7261 taacaatatt ataaacttta aaaaatacag ttatgaagaa gattttattg gcagttacag
     7321 ctgctttagc aattacgggt tgctcacaga atgaagagtt tgagaatgca ggacagaaag
     7381 ctgaaattaa ttttggaagt atagttggta attcaactag ggctgctata atgacaactg
     7441 acggctttga aacatttact gttaatggat ataaaacatc tgataagatg ggggatgcgg
     7501 ttagtttggc atcgtttatg cctaatgaag tggttacgaa aacggatggt gcatggaaac
     7561 atgccaacgt tttttattgg ccaagtaact atgttcagtt ttttgcgact tctcctcaac
     7621 agactttatc actaccaagt aaaggatatc caacatttga ctatactgta ggtggtattg
     7681 ctgatcaaaa agatttattg gttgctaacc aaatagataa acaaaagagt gagaatgctg
     7741 tggagttaaa atttcagcat gctttaactc aggttaattt ctcaattaaa ggtgatacta
     7801 agggatttga ttataaggtg actaacctaa caattagtgg cgtagatggt acaggtacat
     7861 ttaaatttga tggtacagca actgttggtg catgggcaca ggatggaaaa gctgctggta
     7921 catatacagc tacttatgct gagggttcag aaatcacgtt gattaatgtt actgatcttg
     7981 ccgctacaac taagtttgat gctaatccta cagcttcttt atttatgtta ttgcctcaaa
     8041 ctttgaaggc tggtgctaaa gttgctataa cttatacagc tgctcctaca ggaaagacag
     8101 atgttactga cttaaccttc actggaacga aagaagtagc acttacaggt gcatggatcg
     8161 ctggtcagaa ggtacgttat acattaacat tgtctagtga tgctaaagag attactatta
     8221 ctccgactgt gtcagaatgg ggtacatcag aatccgatac ccctttgact ccttctaatt
     8281 aatctttata ataatatact aattaggcat ttaaatggga cagtaatatt ctgtcccatt
     8341 gctatttaaa gtttaaatat ttttctatta accaagttac tgatattact tttaaaatca
     8401 ccattaaaat atagttgtat ttgatttatc ctctcacttc aacctctttt tcacttttct
     8461 ttcttttttt atggcaatat gaaagatttc atatattttt gctggcagca taaacaaaaa
     8521 caaacacagt cagcgtatgc catctatttg tcaaggaacc tgggattgtc aaatatgtcc
     8581 aaaagcggtg agtaatgcca ttactcatgt gatttatcag cgtggttttc ataaaccggc
     8641 tcaaaagtgt gaagaaaatc ttatcctttt tttgatgaag ggagaaatac tggtcaatag
     8701 taaggaatat gcggggacaa tgcttaagga aggtgaattt atccttcagg ccattggctc
     8761 tatgtttgag atgcttgcta tgactgaatg tgagtgcatt tattatcgtt ttatccagcc
     8821 cgaactgttt tgtgatttcc gtttcaatca tatcatgaag gaagtatctc ctccacttat
     8881 ttatactcca ttaaaaataa ttccagaact acaatatttc cttaatgggt ctatcactta
     8941 tctgaaaggg gataaagtct gtcgggattt gctatctctg aaacgaaaag aattggcgtt
     9001 tgtattggga tactattatt ccgattatga tctttcgagc ttggtgcatc cactctctaa
     9061 atatgtaaac agtttccaat acttcgttat tcaaaactat aagaaagtaa agacagtgga
     9121 agaactggca caattgggtg gatataccct tagtacattc cgtcgtatct tcaataacgt
     9181 ctttcatgaa cctgtttatg aatggatgct ggcgagacgt aaagagggca ttctggacga
     9241 cttgaacaac tctaaatgta gcatctcgga gatatgctat aaatatggtt ttgaatcttt
     9301 accccatttt tctaatttct gcaagaaatc ttttggtgcc tctccacgta atttacgtag
     9361 gcaagacatt tcataaatgc aactatgtaa gataattgcg gttcaccggt ttcacccaat
     9421 tctctaaatg ccgatgaata aggtaatagc gggtgaaagc aagggagaaa ttcaggtgaa
     9481 actgaacctt cttggtttca cctattgagt ttattcatac cgactgttgg acatatagat
     9541 ccaaggtgtt ggatatatag ctccaagatg ctagatatat agatgcaaca actcaagtat
     9601 taacacatga gaactaaggt gttaagacct ggcggccaaa gtactacatc cgcacagttc
     9661 actcattaat acctgaaagc ggatttgcta taagcatatc cggattagct ataatgataa
     9721 ttgttttagc tcaagggata ttttaataag acaggtgaaa gcggtaacga atgattttac
     9781 cttatttcaa tcctcgcttt cacccgtaat tctctcattc ataacagttt tggctataag
     9841 gtgaaatcgg tgaaacttat gaattaaaag ttcatgttac tgatccgtat taataataat
     9901 tgtggtctac tcatacataa agaaatcccc tgtcgaacta gccggcaggg gattctgtca
     9961 ttaatcaaat taagctctcg ctattgaaat ctagcagttt ctagtctttt aattttgcga
    10021 tgatgaagtc gcggttcaag cgagcgatgt tgctgataga aatattcttc ggacattcag
    10081 cttcacaagc acgagtgttt gtacagttac cgaatcccag ttcgtccatc tttgacaaca
    10141 tagcttttgc acggcgcaaa gcttccggtt tgccttgcgg caacaagttc aactggctaa
    10201 cttttgcaga aacgaacaac atagcagaac cattcttaca tgcagctaca caagcaccgc
    10261 aaccgataca agaagcagca tccatagctt cgtcagcgat cggtttcgcg atcaggatag
    10321 cgttagcatc ctgcggagca cctgtgcgta cgcttacata accaccagct tgcataatct
    10381 tgtcgtatgc agtacggtct accatcaagt ctttgatgac agggaaacca gccgaacgcc
    10441 aaggttcaac agtgatggta tcaccgtcgt tgaaacgacg catatagatt tggcaagtag
    10501 tagcacctgt tgcaggaccg tgcgggtgtc cgttgatgta aagagaacac ataccgcaga
    10561 taccttcgcg gcagtcatga tcgaatacta ccggttcttt tctttcgctg atgagctgtt
    10621 cgttcagaat atccagcatt tcgaggaagg aagtatcacc ggggatatct ttcatttggt
    10681 aggtttcaaa agcaccttta gctttcggac cagcttggcg ccataccttc agtgtaaatg
    10741 atatattttt atccattttc ttctaattct tttaaatgtt taacttcacc gattagctct
    10801 tgtagttacg agtctgaacc ttgatagctt cgtataccag cggttctttg tgtaataccg
    10861 gagccttttc atcgtcacct tgatattccc agcatgctac atagaagaag ttttcgtcat
    10921 cacgttttgc ttctccttct tcagtctggt attcttcacg gaagtgacca ccacaacttt
    10981 cgttacggtt caatgcatcg taagcaacaa gctcacccat agtgatgaag tcgtacagac
    11041 ggattgcttt gtcaagctct acgttcatac cttctttaga accggggata aacagattcg
    11101 tttcgaattc cttgcggatt tctttcagtt cggcaatacc tttcttcaag ccttctgccg
    11161 tacgtcccat acctacatat tcccacataa catgacccag tttcttgtgg atagaatcaa
    11221 cagattcttt accctggatg ctcatgaact tgtcgatctt agcttgaact gccttttctg
    11281 cttcagcaaa ttcaggaaga tcagtagaga aacgaggaac agtgatttga tctgccagat
    11341 aattctggat ggtataaggc aatacgaagt aaccgtcagc caaaccttgc atcaatgcag
    11401 aagcaccgag gcggtttgca ccgtggtcgg agaagttaca ttcaccgata gcgaacagac
    11461 ccttgatagt ggtttgcagt tcgtagtcta cccagatacc acccattgta tagtggatag
    11521 ccggataaat catcatcgga ttataatatt ttacgccatt aatttctttt gccagttcgc
    11581 ccggattaac gtcagtgatt tcttcgtaca tatcgaagag gttaccataa cgttgaagaa
    11641 caacgtcgat acccaaacgg ttgatagctt cagagaagtc gaggaatacg gccaaacctg
    11701 tgttgtttac accgaaacca gcgtcgcaac gttctttagc ggcacggctg gcaacgtcac
    11761 gcggaaccaa gttaccgaat gccggatagc ggcgttccaa gtaatagtcg cggtcttctt
    11821 ccggaatatc acttcctttg atttcgcctt tctggagttt tacagcatct tctttctttt
    11881 tcggaaccca gatacgaccg tcgttacgga gagattcaga catcaaagtc agcttagact
    11941 gcttgtcacc atgtaccgga atacaagtcg ggtgaatctg aacgtatgca ggatttgcga
    12001 atacagcacc cttgcggtag caagagatag cagctgtaca gttacaaccc atagcgttag
    12061 tagacaggaa gtaagcgtta ccataaccac cggtagcgat tactacagcg tgagcagcga
    12121 aacgttccaa ttcgcctgtt acaagatttt ttgcgatgat accgcgggca cgtccatcaa
    12181 cgatgacaac atcctgcatt tcatagcggg tatacagttt aacagtacct acgtttacct
    12241 gacggctcaa tgcagagtaa gcacccagta gcaactgctg accagtctgg cctttagcgt
    12301 agaaagtacg agatacctgt gcgccaccga aagaacggtt gtccagcgta ccgccatatt
    12361 cgcgagcgaa aggaacacct tgcgctacac attggtcgat gatagcgtta gacacttcag
    12421 ccaaacgata tacgtttgct tcacgggcac gatagtcgcc accttttaca gtatcgtaga
    12481 acagacggta aaccgagtca ccatcatttt gataattctt tgcagcattg ataccaccct
    12541 gtgcagcgat agagtgtgca cgacggggag aatcctgaat acagaaattg aatactctga
    12601 aacccatttc accaagtgaa gcagcggcag aagcacctgc cagacccgta cccacaacga
    12661 tgatgtccaa acgacgttta ttagcggggt tcaccaattt ctggtgagct ttatagttgg
    12721 tccatttctc agccaccggg ccttctggaa tttttgaatc tatcttgatc ataatattat
    12781 ttacaattta atcatttaca atttactatt tagcaagcac cgccacaaat cagtgttttc
    12841 acgaagaata ccactactac cagtgcgaaa ccgagtacaa caatcgtaga atagatgtta
    12901 gaaatacatt tccaacgatt gatccatact ttgttgttcc atcccagtga ttgcatagag
    12961 ctccagaaac cgtgagtcag gtggaaccac aaagcaaaca gccaaacgag gtaaagaact
    13021 acgtaaaccg ggctagagaa agtctgctgg atgtgataag caccgttagc ggcataagcc
    13081 agcgtcagtg tatcagcgtg catgcccatg ttgtgcatca gttccggcaa ctgcattttt
    13141 gcccagaagt tgaagaggtg caaaccaaga cctacgataa cgatcagacc cagcaccaac
    13201 atgttttgag atgcccattc tacagttttt ggtttgtcaa ccactgcata gcgttcgcta
    13261 ccacgcgctt tgcgattctg cattgtcagc cagaatgcgt agatgatgtg aatcacaaaa
    13321 agagcggcta gtcctgcggt agctactaac gcataccagt ttgctcccag gaactcacaa
    13381 atcatgttgt aaccatcagc cgagatgatt gcaaccaagt tcatcgccat gtgaaatgtt
    13441 agaaacagga caagggcgat accggtaacg ctcatcacca ctttccttcc tacag
//
