LOCUS       c00123_gnlPro..        16325 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FNDMBKJJ_123.
ACCESSION   c00123_gnlPro..
VERSION     c00123_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 00:10:17
            Original ID  :: gnl|Prokka|FNDMBKJJ_123
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16325
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16325
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1763:6325]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1764..6325
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..16325
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16325
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             3..137
                     /locus_tag="ctg123_1"
                     /transl_table=11
                     /translation="RKTFAEKPAEFDPRKYLGPARDNMEKLYKHKILNVLGSDNKLAE"
     CDS             complement(216..1367)
                     /locus_tag="ctg123_2"
                     /transl_table=11
                     /translation="MNTEALSTYQEIITNDTANTRAYIEAAECCRSLAKYQQALKYYEQ
                     ALDLNPENKYVRIQYIGLLLSLQKFQDALGESSLMTEKDSSAIALHLQAQSFEGMGELL
                     PATGCYYNIQEKYPDDYLAAAKLAALNIAGSYFNEAIEATEKYRQIDTTNIAVNRQNAL
                     AYCLNKDYPTAIQRYEYLVSQGDSSFHTCYYLGISYYAEEKYYEAHDFLEAARKHDPEN
                     VNLLYYLGRACAKTSWKKLGVEYLEKALDLTIPKDSNMVRLYIGMTDCYKMAQMPKEQI
                     ESIRERYRKYDKQNHKLLYDMAFIYFYSLKDKKNTERCLEAFLKTRPKEDKEEEAKLNE
                     RGELVLGTKNYYNAAANWLKDIQSKQKIEDFFLGGNVPAQKPE"
     CDS             complement(1764..2924)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg123_3"
                     /sec_met_domain="OAD_beta (E-value: 3.7e-153, bitscore:
                     500.7, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDFINFLGNNLADFWTYTGFANATGGHIAMIIIGLGFIYLAVAK
                     EFEPMLLIPIGFGILIGNIPFNMDAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYMIALEMGFDPMQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRLLTTKHERVIRMKPPRAVSHTEKVIFP
                     IIGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDVITILLGLTVGAS
                     TQASEFLTLDSIKIFALGALSFIIATASGVIFVKIFNLFLKKGNKINPLIGNAGVSAVP
                     DSARISQVVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             complement(2926..3360)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 66.7; E-value:
                     4e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg123_4"
                     /sec_met_domain="Biotin_lipoyl (E-value: 2.3e-21, bitscore:
                     66.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYKYKINGNSYKVTIGDIEDNIAHVEVNGTHYKVEMEKQPKAT
                     PKPAVVRPMPNSPAAPTTPVVKPAAPSTGKSGVKSPLPGVILDIKVNVGDTVKRGQTII
                     ILEAMKMENNINADKDGKVTAINVNKGDSVLEGNDLVIIE"
     CDS             complement(3385..4305)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg123_5"
                     /sec_met_domain="OAD_gamma (E-value: 9.7e-15, bitscore:
                     46.2, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTKIGIFLSLLLLIGLTSCGEQKSNNKLLLNEVLIDNQNNFQD
                     DYGLHSAWIEIFNKSYGSADLAACLLKVSSQPGDTVTYFIPKGDILTLVKPRQHALFWA
                     DGEPNRGTFHTSFKLNPETANWVGLFDSGRKLLDQVVIPAGTLGPNQSYARISDGAADW
                     EVKGGSKDKYVTPSTNNKTLDSNAKMEKFEEHDSVGIGMSISAMSVVFCGLILLFIAFK
                     VVGKVAVNLSKRNAMKAKGIDKVEAKELSQAPGEVYAAISMALHEMQDEVHDVEETVLT
                     ITRVKRSYSPWSSKIYTLRENPNRK"
     CDS             complement(4337..5890)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg123_6"
                     /sec_met_domain="CT_Btheta (E-value: 5.6e-290, bitscore:
                     953.0, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKIKELIERRAVARIGGGEKAIAKQHEKGKYTARERLAML
                     LDEGSFEEMDMFVEHRCTNFGMEKKHYPGDGVVTGCGTIEGRLVYVFAQDFTVSAGSLS
                     ETMSLKICKIMDQAMKMGAPCIGINDSGGARIQEGINALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMMEGTSYMFLTGPKVVKTVTGEDVSQENLGGASVHST
                     KSGVTHFTAQTEEEGFELIRKLLSYIPQNNLEEAPYVDCTDPIDRLEDSLNDIIPDSPT
                     KPYDMYEVIGAIVDNGEFLEIQKDYAKNIIIGFARFNGQSVGIVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPIVSLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTI
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVEVLYAREAKDQENPAQFLA
                     EKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRVIRALQQLQTKKLSNPAKKHGNIPL
                     "
     CDS             complement(5921..6325)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg123_7"
                     /sec_met_domain="Glyoxalase_4 (E-value: 5.7e-24, bitscore:
                     75.8, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIEAVEDQKVRTA
                     FLKVGETKIELLEPTCPESTIAKFIENKGAGVHHVAFAVEDGVANALAEAESKEIRLID
                     KAPRKGAEGLNIAFLHPKSTLGVLTELCEH"
     CDS             complement(6499..7497)
                     /locus_tag="ctg123_8"
                     /transl_table=11
                     /translation="MPLKLTTYYRGKDIPDLPGTNTFHSKELFQIYESTPGYTPLLIVA
                     TEEGRPVARLLAAIRKTKKWLPSSLVKQCVVYGAGEFLDTSLPASKEKEEEIFGEMLEH
                     LTQEASRTCILIEFRNLDNSMFGYRFFRKNDFFPVNWLRVRNSLHSTQKAEDRFSPSRI
                     RQIRKGLKNGAKVVEAHTVEEIKEFSRMLHKVYSSRIRRYFPANDFFRHMNSMLIRGKQ
                     AKIFIVKYKEKIIGGSVCIYSGENAFIWFSGGMRKTYALQSPGILAVWKALEDAHERGF
                     RHMEFMDVGLPFRKHGYRDFVLRFGGKQSSTRRWFRISWPWLNNLLVKFYV"
     CDS             7800..10940
                     /locus_tag="ctg123_9"
                     /transl_table=11
                     /translation="MILGLTLLCAPSAISVYAENGVNDITVQAVMQTKTVKGTVLDENG
                     EPLIGVSIVVKGTSTGTITDFDGKFSINLPAGSKELVVSYIGYKEQAIIVSGNAPLNIK
                     MVPDTQALDEVVVIGYGTVKKRDLTGAVASVKSEDITMNPGVNPMDALQGKIAGLDITN
                     SSGQAGSSPTVQLRGTRSLQLDEDGNISSDAFKPTYIIDGMPGDIATLNPNDIESIEVL
                     KDASSTAIYGSSGANGVIIVTTKGSKSGKPVINFNAYAGTTMGARVPKMRTGDSYINYI
                     KDSYKPVGTTNEEEIFGERYDAIKNNQWVNWGDEVLHSGLKQNYSISVAGGTEKTKAYF
                     SLNYTDEKSMYENDDYKVYSTRVRIDQEINKWINAGINVQASFSNKNSRNAVLERALFA
                     TPLGVPYNEDGSITEFPIPGSSSDPNPLADEQDGVYKNNTKAGRAYVDAYLEWKPVKGL
                     SVKSQLGGSYSQSRAGKFMGEGSYNVLKGSTVAYGEATNKTGYNYKWENIVTYHNTFNK
                     AHDLTITGVTSWNYNQSEEYYVYGENPATNDMLWYALQNADNKKLNSKYLMSKGMGFIG
                     RVNYSYKGKYLFSASSRYEADSRLSKDNRWNLFPAVSVGWRISDEAFMAGTKSWLDNLK
                     LRVGYGVAGTTAGIAEYSSMASLENVTTSLGGMTVPSAKFTEYITNRNLTWEKTHDLNI
                     GIDASFLNNRIDLTVDLYRTKTTDVILSQALPTSIMGNYTGSTTYKMNKNAAETENRGI
                     ELALNTRNIVKKDFTWSSTVTFTANKEKIKSLIEGQDMMFNAKKGDMVFKVGEGVGSFY
                     RYKVLGIWQYSEKETAALFGCEPGDIKLDLPSVKKDGNGYYYMNPEGERVDITAENPYG
                     VRADYDRQVIGRNTPDWTLGFKNNFRYKDFDLSVFLYARWGQMMNYGSVIGKYSPNPDY
                     NIPTYFTYYDKTIEADQDVLFYAIDKSKDRSAYEGYDSMYYVDGSFFKLKNVTLGYTLP
                     GKLTKRFGISNLRVYATMTNLFTYSPNKYVKNYDPEMNGSINFPLSRDCIFGLNLTF"
     CDS             10952..12907
                     /locus_tag="ctg123_10"
                     /transl_table=11
                     /translation="MKKIYSLVLLVAGVFSWGSCSLDEVNPNNSGQFSDGSYTLETYKA
                     FTNSCYTALINNIYQSSDYLVCTEAGTDIWEEPKSGSSYQRYHSYNGMKTDDSYYYKVW
                     QYSYLCINSCNIVIDGAENVTGDENEINECVAQARCLRAYYYMNLVEQFGNVDLQLKAA
                     DSENISFDAHRSTVPEIYATIIEDLKFAVENLPVSFSDYYSRVTKKSAMGLLARAYING
                     AGYDLKDTDGVSFLEKAYDTATTMINNKAIYEWYMHPAFADVFNENNNRNNEEALFIAA
                     GAERNSDAYTNGNYSQSEMFRHFLPSLGTYTDLGLVDKTSNFVYGRPNSNIFLPSKYLM
                     DCFAADMNDSRFRYSFISAYSSYSIPAWGATYEYGGSACAKEITSTLATKFGIPASNIG
                     KKVYPHFNLESNSTADANYCQLAIWNADGTAKTTQDKTDGNILHPAMPLDPAEAHQYAV
                     YCSLKTLTEEEKAQYPGLVLNVFDLYDENGTARATYDKPSAASALWLSIYPALSKFNMP
                     GNKFVGRDVQRKTVDVMIMRMAEVYLIAAEASVRLNKGDAAKYINVLRTRAGAGTVSES
                     QVDLNYVFDEYARELCGECGRWYLLKRNAAFETRLAAYNKRAAEHFKKEFYLRPIPTKY
                     LDAINNPAEFGQNAGY"
     CDS             13094..13636
                     /locus_tag="ctg123_11"
                     /transl_table=11
                     /translation="MIEEMLAYNREFVKNEGYKEYITNKYPDKKIAILSCMDTRLTALL
                     PAALGIKNGDVKMIKNAGGVISHPFGSVIRSLLVAIFELGVEEIMVIAHSDCGACHMHS
                     EEMLEKMKARGINADYIHMMSFCGVDFHSWLDGFEDTEKSVRGTVDFIVHHPLIPSDVK
                     VHGFIIDSTTGELTRIV"
     CDS             13828..14571
                     /locus_tag="ctg123_12"
                     /transl_table=11
                     /translation="MHSFVTNGVSVLFDFCLTAGFTIRFDVIVLCNSFFHNEYISQCKD
                     TISFLITIGLRYLCIHKSNENGNNMENFSELIKNRRSMRKFTDEELTQDEVVALMKAAL
                     MSPSSKRSNSWQFVVVDDKEKLKELSHCKEQASSFIADAALAIVVMADPLASDVWIEDA
                     SIASIMIQLQAEDLGLGSCWVQVRERFTATGMPSDEFVHGILDIPLQLQILSVIAIGHK
                     GMERKPFNEEHLQWEKIHINKFGGK"
     CDS             14574..14909
                     /locus_tag="ctg123_13"
                     /transl_table=11
                     /translation="MGAVKANNNKDTYKATAVAFIVIGTLFLINKLLPFASIGLPWVMN
                     KDNLLLYASISFLIFKRDKSVGFVLLGLWLVMNIGLVMSLLGSLSGYLLPLALLIIGII
                     LFWVSKR"
     CDS             14917..15711
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Shikimate_DH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) F420_oxidored"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg123_14"
                     /sec_met_domain="Shikimate_DH (E-value: 1.5e-10, bitscore:
                     32.5, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="F420_oxidored (E-value: 8.2e-13, bitscore:
                     40.1, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRSIEDTPVVFLGAGNLATNLAKALYRKGFRIMQVYSRTEESAR
                     TLANEVEAEYITDLKGVSNEARLYIISLKDAAFVELLPQITDGKQHALLVHTAGSIPMN
                     IWEGHAERYGVFYPMQTFSKQREVDFREVPFFIEAKRPEDAELLKAVAGTLSDKVYEAD
                     SEQRRSLHLAAVFTCNFTNHMYALAAELLEKYHLPFDVMLPLIDETARKVHELAPRDAQ
                     TGPAVRYDENVMNKHLSMLAGSQALQEIYKLMSKSIHEHHQL"
     CDS             15692..16213
                     /locus_tag="ctg123_15"
                     /transl_table=11
                     /translation="MSTINYDLSRIKALAFDVDGVLSSTTVPLHPSGEPMRTVNIKDGY
                     AIQLAVKKGLHIAIITGGRTEAVRIRFAALGVKDLYMGSAVKIHDYRDFRDKYGLSDDE
                     ILYMGDDVPDIEVMRECGLPCCPKDAVPEVKSVAKYISYADGGHGCGRDVVEQVLKAHG
                     KWMAEDAFGW"
ORIGIN
        1 tccgtaagac tttcgctgaa aaaccagctg aattcgaccc acgtaagtat cttggtccgg
       61 ctcgtgacaa catggaaaaa ctgtacaagc acaaaatcct taatgtgctg ggttcagaca
      121 acaaattggc tgaataatca cagattatcc tattatatag aaaggctgca atcgtttgac
      181 ggttgcagcc tttttacgta atattctcta tctgcttatt ccggtttctg agcgggcaca
      241 tttcctccca agaagaaatc ttctatcttt tgcttacttt gaatgtcttt cagccagtta
      301 gctgcagcat tataataatt cttagtgcct aaaacgagtt cgcctcgttc gtttagtttc
      361 gcttcttctt ccttatcttc tttcgggcgt gtttttaaga atgcttccag acagcgttcg
      421 gtgtttttct tgtctttcag cgaatagaaa taaatgaaag ccatatcata gagcagctta
      481 tgattttgtt tatcgtattt ccggtagcgt tctctgatcg attcaatctg ctctttaggc
      541 atctgtgcca ttttgtagca gtcggtcatg ccaatataga gccgtaccat attactgtct
      601 ttgggaatag tcagatcaag cgctttttcg agatactcta cgcctaactt cttccatgaa
      661 gtcttggcgc aggcacggcc gagataataa agcaggttta cgttttcagg atcatgtttt
      721 cgggcggctt ccagaaagtc atgtgcttcg taatatttct cttccgcata atagctgata
      781 cccagataat aacaggtatg aaaagaactg tcgccctggc tcaccaggta ttcataacgc
      841 tggatagcgg taggataatc cttattcaga caatatgcca gtgcattctg gcggttgaca
      901 gcgatgttgg tggtgtcaat ctgccgatat ttctccgtgg cttcaattgc ttcgttgaaa
      961 taagaaccgg ctatgttcag tgcggcgagc ttggcggcgg caagatagtc gtcggggtat
     1021 ttctcctgta tattatagta gcaccccgtg gcggggagaa gctctcccat accttcgaaa
     1081 ctttgggcct gcagatgcaa ggcgatggcg gaactgtctt tctctgtcat cagactactt
     1141 tctcctaaag catcctgaaa cttctgtaaa gagagcagta gtccgatgta ttgaatacgc
     1201 acatatttgt tttccggatt cagatcaagt gcctgttcat aatatttcag tgcctgttgg
     1261 tatttggcca atgaacggca gcattcggct gcttcgatat atgcacgggt attggcagtg
     1321 tcattggtta tgatttcctg ataagtggaa agtgcttctg tattcatccc aagtccccgt
     1381 tgtgctttac ctttttgcaa gagtagggga attgtcggct tttctttggc aatgagagtg
     1441 agagctgcct cgtaatcgta gtttgctatt gcttcctgaa catgattgat gcgctgcgcc
     1501 atcaccaggg tggtggtaca aaggaaggcg aggagaataa tccgtttcat aaatatttat
     1561 tttagtgtgt cgtaacaaag acgcaagatg ctaaaaaata tcgtatttac gaattattcg
     1621 tagccttttt ggaatagatt aacggaatga taagagaaga taacataatg ataagtgcgg
     1681 atattgcatc taaaacagca atatccgcac ctaatatttt gtcccggcat tccgaatgga
     1741 agcctgacag gggcaccttg tccctacatt aagaatccta acaggatacc ggcagcaaca
     1801 gctgaaccga ttacacctgc tacgttcgga cccatagcgt gcatcagcaa gtagttggtt
     1861 ggatcatatt ccagaccgac aacttgtgag atacgtgcag agtcgggaac ggcagataca
     1921 cctgcattac cgatcaacgg attgatctta ttgcccttct tgaggaagag gttgaagatc
     1981 ttaacgaaga tcacacctga tgcggtagca atgataaatg acagtgcacc gagggcaaag
     2041 atcttgatgg agtcgagtgt caggaactcg gaagcctgag tagaggcacc tactgtcaaa
     2101 cctaacagga tagtgataac gtcaatcagc ggaccgctgg ctgtgttagc cagacgacgg
     2161 gttacaccac tttctttcaa caggttaccg aagaacagca tacccagcag aggcagaccg
     2221 gaaggaacca ggaagcaggt cagcaacaga ccgataatcg ggaaaatcac tttctctgta
     2281 tgagaaacgg cacgtggcgg tttcatacgg ataacgcgtt cgtgtttggt ggtgagcaga
     2341 cgcatgatag gcggctgtat caccggaact aacgccatat aggagtaggc ggataccgca
     2401 atggctccca ttaagttagg tgccagcttg gacgaaagga agatagccgt cggaccatct
     2461 gctccaccga tgataccgat agcaccggcc tgcatcgggt caaatcccat ttccaatgcg
     2521 atcatgtatg caccgaagat accaaactgg gcagccgcac cgatcagcat cagcttcgga
     2581 ttggagatta gcgccgagaa gtctgtcatg gcaccgatac ctaagaagat gagcggtgga
     2641 taccagccgg acgttactcc ctgatacaat atgttcaata cagaaccttc ttcatatata
     2701 ccgactttta gtccggcgtc catattgaaa ggtatattac cgatcagaat accgaatccg
     2761 ataggaatta acaacatcgg ctcgaactct ttggctacag ctaagtaaat aaagcctaaa
     2821 ccgataatga tcatagcaat atgtccacct gtcgcgttgg caaatcccgt gtaggtccag
     2881 aaatcggcaa ggttatttcc taaaaagtta ataaaatctc ccatattatt caataattac
     2941 gaggtcatta ccttcaagaa cagaatctcc cttgttgaca ttgatggcag tcactttacc
     3001 gtctttgtct gcattgatat tgttttccat cttcatggct tccaatataa tgatagtctg
     3061 tcctcttttc actgtatcac ctacatttac tttgatgtca aggataacgc ctggcagtgg
     3121 ggacttaacg cctgatttgc cggtagaagg agcagccggt tttactaccg gtgtggtagg
     3181 agcagccggt gagttaggca tagggcgtac tactgccggt ttgggagtag ctttcggttg
     3241 tttctccatt tctactttgt aatgcgtacc gttcacttct acatgagcga tattatcttc
     3301 aatatctccg atggttactt tgtatgagtt accgttgatt ttatatttat attctttcat
     3361 cgttttatct ttttagggaa tgatttactt tctgttagga ttttcacgca aggtgtaaat
     3421 cttcgaactc cacggtgaat aactgcgctt cacacgagtg atggtcagca ccgtttcttc
     3481 tacgtcgtgt acctcatcct gcatttcgtg taatgccatt gaaatagcag cataaacttc
     3541 acccggagcc tgtgaaagct ctttcgcttc gactttatcg atgcctttag ccttcatcgc
     3601 attgcgtttg ctcaggttga cagcaacttt acctaccacc ttgaaggcaa tgaagagaag
     3661 aatcaatccg cagaatacta cgctcatggc tgaaatagac ataccgatac cgactgagtc
     3721 atgttcttcg aacttttcca tcttggcatt actgtcaagg gttttgttgt tcgtgctcgg
     3781 ggttacgtat ttgtctttgc ttccgccttt tacttcccag tctgctgctc cgtcgcttat
     3841 gcgtgcataa gactggttgg gacctaaagt tcctgctggt atgacaactt gatcaagtag
     3901 ctttctgcct gaatcaaaaa gaccgaccca attggctgtt tcgggattca gtttgaagct
     3961 ggtatggaag gttccacgat taggttcgcc atctgcccaa aataacgcat gttggcgtgg
     4021 ctttactaat gtaagtatgt caccttttgg gataaaatag gttactgtat cgcccggctg
     4081 gctgcttact ttcaataaac aagctgctaa gtctgcgcta ccgtatgatt tgttgaatat
     4141 ttcaatccat gcactgtgca agccgtagtc atcctgaaag ttgttttgat tgtctatcag
     4201 gacttcattc agcaatagct tattgttcga cttttgctct ccgcaggaag tcaatccaat
     4261 cagcaacagc agagaaagga atattccgat tttggttttg ttcataatcg ttcttgtttt
     4321 aatgtgaaaa gtaggattac aacggaatat taccatgctt cttagccgga ttactcaatt
     4381 tcttagtctg caactgctgc aaagcacgga tcacacggaa acgtgtgttg cgcggttcaa
     4441 tcacatcgtc gatgtagcca tatttagctg cattgtaagg attggcgaac aatttcgtgt
     4501 attctgcttc tttctctgca aggaattgag ctgggttttc ctgatctttg gcttcgcgtg
     4561 cgtacaatac ttctactgct cctgcaccac ccattactgc gatttcggca gtaggccatg
     4621 cgtagttcat gtcaccgcga agttgcttac agctcattac gatgtgagaa ccaccgtaag
     4681 atttacgcaa tgtgatagta actttaggca cagtagcttc accgtaagca tacaacagtt
     4741 tagcaccatg gaggataacg ccattgtatt cctgacctgt tcccggaagg aagcccggta
     4801 cgtctaccaa cgatacgata ggaatattga atgcatcgca gaaacgaacg aaacgtgcac
     4861 ccttacgaga tgcgttacta tcgagcacac cagccagata cttaggctga ttagcaacga
     4921 tacctaccga ttgtccgttg aaacgggcga aaccgatgat gatattcttt gcataatctt
     4981 tctggatttc aaggaattca ccgttgtcca caatagcgcc gatcacttcg tacatgtcat
     5041 acggtttagt agggctgtcg gggataatat cgttcaaaga atcttccaga cggtcgattg
     5101 ggtctgtgca atctacataa ggagcttctt caaggttgtt ttgaggaata tagctcaaca
     5161 gtttgcgaat cagttcgaaa ccttcttctt ctgtttgggc ggtgaaatga gtcacacccg
     5221 atttagtgga gtgaacgctt gcgccaccga ggttttcctg gctaacgtct tcacctgtaa
     5281 cggtcttcac cactttcggt ccggtgagga acatataaga agtgccttcc atcatcagtg
     5341 taaagtcggt cagagccgga gaataaacag caccaccggc acaaggaccg aagataccgg
     5401 aaatctgcgg aataacacct gaagcaagga tgttgcgttg gaagatttct gcataacctg
     5461 ccaaagcgtt gataccttcc tggatacgtg caccacccga gtcgttgata ccgatacaag
     5521 gagcacccat cttcatggcc tgatccataa ttttacaaat cttcaatgac attgtttctg
     5581 acagtgaacc ggcagaaact gtgaagtcct gtgcgaacac atataccaga cgtccttcga
     5641 ttgtaccgca gccggttact acaccgtctc ccggataatg ttttttctcc attccgaagt
     5701 tcgtgcatct gtgctcaacg aacatgtcca tttcttcgaa gctaccctcg tcaagcagca
     5761 tagccagacg ctcgcgtgct gtgtatttcc ctttttcatg ttgcttcgca attgcttttt
     5821 cgccgcctcc gatacgtgct acggcacggc gttcaataag ctctttaatt ttttcaagtt
     5881 gattactcat gagttcttgt tgttttttta gagtttatga ttagtgttcg cagagttctg
     5941 tcagcacacc cagtgttgat ttcgggtgaa ggaaagcgat gttcagacct tcggcacctt
     6001 tgcggggagc cttgtcaatc agacggattt ctttgctttc tgcttctgcc aaagcattag
     6061 ctacgccatc ttctacggca aatgctacgt gatgaacacc tgcacctttg ttttcaataa
     6121 atttagcaat ggtgctttcg gggcaagtcg gctccaacaa ttcgattttt gtttcaccta
     6181 cctttaaaaa agcggttctt actttttgat cttctactgc ttcgatgttg taacatttca
     6241 gacccaatac gttttcgtag taaggaaggg cttcttcgat gctttttaca gcaatgccca
     6301 gatgctcaat gtgtgaaatc ttcataacta tattttttta tatggtttaa ttatgtgctt
     6361 atatggcata aaacagcaca aagaaagaca tttcttgtct aataaagaaa tatttctgca
     6421 tttaattatt ggggaataaa gcataaaaaa tgctccggat gggtgacaaa gacgggtttt
     6481 gtaatcttga gattacattt agacataaaa cttgaccaga agattattca gccatggcca
     6541 gctgatacgg aaccagcggc gggtactgct ttgtttgcct ccgaaacgga gtacgaaatc
     6601 acgataacca tgcttgcgga agggaagtcc tacatccatg aactccatgt gacggaatcc
     6661 ccgttcatgg gcatcttcaa gtgctttcca tactgccagt atgccgggtg actgcagtgc
     6721 ataggtcttt cgcattcctc ctgaaaacca gataaaagca ttttcgccgg aatagatgca
     6781 gacggagccg ccgataatct tttccttgta ttttacgatg aatatttttg cctgttttcc
     6841 tctgataagc atgctgttca tgtggcggaa aaagtcattg gcagggaaat atctccgtat
     6901 tcgtgaagaa taaactttgt gcagcatccg cgagaattcc ttaatctctt ccaccgtatg
     6961 ggcttctact actttggctc cgtttttgag ccctttccgg atctgacgga tacgtgatgg
     7021 gctgaaacgg tcttccgctt tctgcgtact atgcagagag ttacggacac gcagccagtt
     7081 gactggaaaa aagtcgttct ttcggaagaa acggtaaccg aacatggaat tatccagatt
     7141 gcggaattca ataagaatgc aggtgcgtga tgcttcttgt gtgagatgct ccagcatttc
     7201 accgaaaatt tcttcctcct tctctttact tgccggtaga gaagtgtcca gaaattcacc
     7261 tgcaccatat accacacatt gtttgacaag agaggaggga agccactttt tggtcttgcg
     7321 tatggcggca agcaggcgtg ctacaggtct gccttcttct gttgccacta tcagtagcgg
     7381 ggtatatccc ggagtcgatt catagatctg aaacaactcc ttggaatgaa aagtattggt
     7441 tcccggtaaa tcgggaatgt cttttccgcg ataatatgtt gttagtttaa gtggcatcca
     7501 aatacaaatt tacacttttt attcttcatt caacaataaa aaagagaatt tgttggctta
     7561 gcctaaaatt tgtcttttta tcctttgcat atatttgagg aaaaaaaggc ttggaaaagc
     7621 gaatttttgt attattgtcg tcctttgtga gtacagaagt aaaatggaaa cgtctatgta
     7681 aaagattatg ctaattgtat tttactaaac aaaggaaaat taatattaac tttaaattaa
     7741 aacgaatgag agagaatgca tttgttgaag cgtggaagac acagcataga cgcgtttcca
     7801 tgattttagg gctgacttta ttgtgtgccc cttctgccat atctgtttat gcagaaaatg
     7861 gtgtgaatga tattactgtg caagccgtca tgcagacaaa gacagtgaaa ggaactgttt
     7921 tagatgaaaa tggagaaccg ttgatcggtg tttctattgt ggtgaaaggt acaagtacag
     7981 gtacgataac tgattttgac ggtaagttct ccattaatct tccggccgga agtaaagaac
     8041 tggttgtttc ttatatcgga tataaagaac aggctatcat tgtgagtgga aatgccccgc
     8101 tgaatataaa gatggttccg gatacacagg ctttggatga ggtagtggtc atcggttacg
     8161 gtacggtaaa gaaacgtgat ttgacaggtg cggttgcttc tgtgaaatca gaggatatca
     8221 ccatgaatcc gggcgtgaat ccgatggatg cgctgcaagg taaaattgca ggtctggata
     8281 tcactaattc ttcaggtcag gcaggttcgt caccgacagt tcagttgcgt ggtacccgct
     8341 ctttacagtt ggatgaggat ggtaatatct cttcagatgc atttaagccg acttatatta
     8401 tcgatggtat gccgggtgat attgctacct tgaatcccaa tgatattgaa tctatcgaag
     8461 tactgaaaga tgcatcttct acagctatct acggttcaag tggtgcgaat ggtgttatta
     8521 tcgtgactac gaaaggatcc aagagtggaa aaccggtcat caattttaat gcttatgccg
     8581 gaacgactat gggtgcccga gttcctaaga tgcgtacggg tgactcatac attaattata
     8641 taaaagattc ttataagcct gtcggtacta ccaatgagga ggaaattttc ggtgaaagat
     8701 acgatgccat caaaaacaac caatgggtaa actggggaga tgaagtatta cactcaggct
     8761 tgaagcagaa ctatagtatt tccgttgccg gaggtactga gaagacgaaa gcttatttct
     8821 cgttgaacta tactgatgag aagagtatgt atgagaatga tgactataaa gtgtactcta
     8881 cccgtgtccg tatagatcag gaaatcaata aatggattaa tgccggtatt aatgttcagg
     8941 catctttctc caacaagaat tcacgtaatg ccgttttaga aagagcattg tttgctaccc
     9001 cattgggtgt tccttataat gaagatggct ctatcacgga attcccgatt ccaggttcat
     9061 catcagaccc gaatccgtta gcagacgaac aggatggagt atataagaat aatactaaag
     9121 caggaagggc ttatgttgac gcttatctgg aatggaaacc ggtaaaagga ttgtctgtca
     9181 agtcacagct tggaggcagt tattctcaat ctcgtgccgg taaatttatg ggagaaggct
     9241 cttataatgt gttgaaaggc agtacggtgg catatggcga agctaccaat aagacgggat
     9301 ataattacaa atgggaaaac atagtaactt atcacaatac atttaataaa gctcatgacc
     9361 tgacaattac aggggttact tcctggaatt acaatcagag tgaagaatat tatgtctatg
     9421 gtgaaaaccc ggcgaccaat gatatgttgt ggtatgcatt gcagaatgct gataataaga
     9481 aactgaacag caaatatctg atgtcgaagg ggatgggctt tatcggtcgt gtcaactact
     9541 catacaaagg taaatacctg ttctctgctt ccagtcgtta tgaagcggat tcccgtttgt
     9601 cgaaagacaa tagatggaat ttattcccgg cagtttctgt aggctggaga atctcggatg
     9661 aagcatttat ggctggtaca aaaagctggt tggataactt gaaactgcgt gtaggctatg
     9721 gtgttgccgg aactactgcc ggtattgctg aatacagttc tatggcatct ttggaaaatg
     9781 tgacaacctc tttgggagga atgactgttc cgtcagccaa gtttacggag tatatcacta
     9841 accgtaatct gacatgggaa aagactcatg acttgaatat tggtattgac gccagcttcc
     9901 tcaataatcg tattgatctg acggtggatt tgtatcggac aaaaacaacg gatgtaattc
     9961 tttcgcaggc attgccgaca tctattatgg gtaattacac aggtagcact acttataaaa
    10021 tgaacaagaa tgctgctgaa acagaaaatc gcggtattga acttgctctt aatacccgta
    10081 atattgtgaa gaaagatttt acttggagct caacagtgac atttaccgcc aacaaagaaa
    10141 aaattaaatc tttgatcgaa gggcaggata tgatgttcaa tgcaaaaaag ggtgatatgg
    10201 tgttcaaagt cggcgaagga gtcggttctt tctatagata taaagtgttg ggtatctggc
    10261 aatatagcga aaaggaaact gctgctttgt tcggatgcga accgggcgat attaagctgg
    10321 atttacctag tgtgaagaag gacggaaatg gttattatta tatgaatcct gaaggagagc
    10381 gcgttgatat tacggcagaa aatccttatg gtgtacgtgc ggattatgat cgtcaggtaa
    10441 taggtcgtaa tactccggac tggacattgg gctttaagaa taatttcaga tacaaagatt
    10501 ttgatttgtc tgtcttcctt tatgcacgtt gggggcaaat gatgaactat ggcagtgtga
    10561 taggtaaata ttcgcctaat ccggattaca atattcctac ttattttact tactatgaca
    10621 agacgatcga agcagatcag gatgtcttgt tctatgctat cgataaatcc aaggatagaa
    10681 gtgcttatga aggatatgat tcgatgtatt atgtggatgg atcattcttt aaacttaaaa
    10741 acgtaacatt gggttatacg ttacccggta aacttacaaa acgttttggt atcagtaatc
    10801 tgagagttta tgcgacaatg accaacctgt ttacttattc gccaaacaaa tatgtgaaga
    10861 attacgatcc ggaaatgaac ggaagcatca acttcccatt gtctcgtgat tgcatatttg
    10921 gtcttaattt aactttctaa aaaatagcaa tatgaaaaag atatatagtt tagttctact
    10981 tgttgccggt gttttttctt ggggctcttg cagtcttgat gaagtgaacc ccaacaactc
    11041 gggtcagttc tccgatggtt cttatacatt ggaaacttat aaggcattca ccaactcgtg
    11101 ctatacagcc ttgatcaaca acatctatca gagtagtgac tatctggttt gtacggaagc
    11161 gggtactgat atttgggaag aacccaaatc gggctccagc tatcagcgtt atcatagtta
    11221 taacggtatg aaaaccgatg atagctatta ttataaagtg tggcaatatt cttatctgtg
    11281 tatcaacagc tgtaatattg tgattgacgg agctgagaat gtgacagggg atgagaatga
    11341 aatcaatgaa tgtgtggcac aggccagatg tctgcgtgct tactattata tgaatttggt
    11401 ggagcagttt ggaaatgtcg atttgcagtt gaaggctgcc gatagcgaga atatttcttt
    11461 tgatgctcac cgttctaccg ttcccgaaat ttatgctacc attatcgaag acctgaagtt
    11521 tgccgtagag aatctgcccg taagtttcag tgattactat agccgcgtta caaagaaatc
    11581 ggcgatggga ttattggcac gtgcatatat taatggtgcc ggttatgatc tgaaagatac
    11641 cgatggtgtc agctttctgg aaaaagccta tgatacggcg acaaccatga ttaataataa
    11701 agcgatttat gagtggtata tgcatcctgc ttttgccgat gtattcaacg aaaataataa
    11761 tcgtaacaat gaagaagctc tgttcattgc tgcgggtgcc gaaagaaatt cggacgctta
    11821 caccaatggt aactactcac aaagtgaaat gttccgtcac ttcttacctt cgttgggaac
    11881 atatacggat ctgggtttgg tagacaagac ttcaaacttc gtttacggtc gtccgaacag
    11941 taatatcttc ctgccatcca aatatctgat ggactgtttt gctgctgata tgaacgactc
    12001 tcgttttcgt tattcattta tctcagctta ctcgtcttat tctataccgg catggggggc
    12061 gacttatgaa tatggaggtt cagcgtgtgc caaagaaatc acaagcacac ttgctactaa
    12121 atttggtatt cccgcatcta atataggtaa gaaagtttat cctcatttta acttggaatc
    12181 caatagtaca gccgatgcta attactgcca gctggctatc tggaatgcag atggaacagc
    12241 gaagactact caggataaaa cagatggtaa tattcttcat cctgctatgc ctttagatcc
    12301 ggcagaagct catcaatatg ccgtttattg ttctttgaag acgctgacag aagaggaaaa
    12361 agctcaatat ccggggttgg ttcttaatgt tttcgatctt tacgatgaga atggaacagc
    12421 cagggctacc tatgacaagc ctagtgctgc cagtgctttg tggttatcta tttatccggc
    12481 tctttctaaa ttcaatatgc cgggtaataa gtttgtcggc agagacgttc agagaaaaac
    12541 tgtggatgtg atgatcatgc gtatggcgga agtttacctg attgctgctg aagcatcggt
    12601 acgcttgaac aagggagatg ctgccaaata tattaatgta ctccgtacgc gtgccggtgc
    12661 cggtacggtc agtgagtcgc aagtggatct gaattatgtt ttcgatgaat atgcccgtga
    12721 actttgtggc gaatgtggcc gctggtattt gctgaaacgt aatgctgctt ttgagactcg
    12781 tttggctgct tataataagc gtgctgccga gcactttaag aaagaattct atttgcgtcc
    12841 tattcctacg aaatatctgg atgcgatcaa taatccggca gaattcggac aaaacgccgg
    12901 ttattaatca gttaattaat aatcaagcat aattaatagg agccgggcag gagatttctc
    12961 ttgtccggct ctttgtttcc agacctgtat cctacgtaaa agtttaaaaa ggatttccgg
    13021 tatattttca ttatttcctg atacagcctt ttattatttt ctttattttt gtgtgtccaa
    13081 acaaaatagc gctatgatag aagaaatgct tgcttataat agagagttcg ttaagaacga
    13141 gggatataaa gaatatataa cgaataagta tcccgataaa aagattgcta tcttatcctg
    13201 tatggataca cgcctgacag ctttactccc ggccgcacta ggcattaaga acggagacgt
    13261 taaaatgatc aagaatgcag gaggcgtcat ttcccatcct ttcggtagtg tgattcgcag
    13321 tctgcttgtc gctatcttcg agttaggtgt ggaggaaata atggtgattg cccattctga
    13381 ttgtggagcc tgccatatgc acagtgaaga aatgcttgag aagatgaagg cacggggtat
    13441 taatgccgat tatattcata tgatgagttt ttgtggagtc gattttcatt cttggctaga
    13501 tggctttgaa gatacggaga agtcggtaag gggaacggtc gattttatag ttcatcatcc
    13561 tttgattccg tcggacgtga aagtgcacgg gtttatcata gactccacta ctggagaact
    13621 gacgcgaatt gtataggaaa tcgccctttc tgcctatcag gaactgcata aaacatggtg
    13681 tcactatcgc aacaggatag tgtcactatc actgtctcat ggtgtcacta tgtcattggg
    13741 ataccgacac tatcccaaat gaaaaaaata aggcagcttt ttatcggctg cctttatctt
    13801 tctgcggtta tatactttct ttgactcatg cactcgtttg taacaaacgg ggtgtccgtg
    13861 ctctttgatt tctgcctcac ggctggcttt acgattcgct ttgatgtaat cgtcttgtgt
    13921 aattcgtttt ttcataatga atatatttct cagtgcaaag atacaatttc atttcttatt
    13981 acgatcggtt tgcgctatct ttgcatacat aaatcaaatg aaaacggaaa taatatggaa
    14041 aatttcagtg aactgataaa gaatcgccgc agtatgcgca aatttacgga tgaggagtta
    14101 acacaggatg aggttgtggc actgatgaaa gctgccttaa tgtctcccag ttccaaacgt
    14161 agtaatagct ggcagtttgt ggtagtcgat gataaagaaa agttgaaaga actgtctcac
    14221 tgcaaagaac aggcttcttc tttcattgca gacgctgctt tggcgattgt cgtgatggca
    14281 gatccattgg cgagcgatgt ctggattgaa gatgcttcta ttgcttccat catgatacag
    14341 ttgcaggcgg aagatttggg gctgggaagc tgttgggtac aggttcgcga acgtttcact
    14401 gcaaccggaa tgccgtctga cgagtttgtt catggaattt tggatattcc tttgcaactg
    14461 cagattcttt ccgtgattgc catcggacat aagggaatgg aacgtaagcc tttcaacgaa
    14521 gaacacctcc agtgggagaa aattcatatt aataagttcg gaggaaaata acgatgggag
    14581 ctgtcaaagc aaataataat aaagatactt ataaggctac tgccgtcgct tttattgtta
    14641 tcggaactct tttcctgata aataaactgc tcccctttgc ttctataggt ttgccttggg
    14701 tgatgaataa ggacaatttg ttgttgtatg cctctatcag ttttcttatt ttcaagcgtg
    14761 acaagtcggt cggctttgtg ctgttgggac tgtggctggt aatgaatatc ggtttggtaa
    14821 tgtcattgct cggttccttg tccggttatc tgttgccatt ggcactgttg atcatcggaa
    14881 ttattttatt ttgggtttca aaacgttaaa gaaacaatga aaagaagtat tgaagatacg
    14941 cccgttgtgt ttctcggcgc cggaaatctg gcaactaatc tggcgaaagc gctttaccgg
    15001 aaaggattcc gtatcatgca ggtgtacagc cgaacggaag aatcggctcg tacgttagcc
    15061 aatgaagtgg aagcggaata tatcactgat ttaaaaggcg tatcgaatga agcgagatta
    15121 tatattattt cattgaaaga tgccgctttc gtcgaactgt tgcctcagat cactgatggg
    15181 aagcagcatg cgctgctggt acatacggca ggtagcatcc cgatgaatat ttgggaaggt
    15241 catgcggaac gctacggagt attttatccg atgcagacgt tcagcaaaca acgtgaagtt
    15301 gattttcggg aagtaccttt ctttattgag gcaaaaagac cggaagatgc cgagctgctg
    15361 aaagcggttg ccggtacgct ctctgataag gtgtacgaag ccgattcgga gcaacgcaga
    15421 agtcttcatc tggcagccgt ctttacctgt aactttacca accatatgta tgctcttgcc
    15481 gccgaattgc tggaaaaata tcatttgcca tttgatgtca tgcttcccct gattgacgaa
    15541 acggcacgca aagtgcatga actcgctcct cgtgatgcgc agaccggacc ggctgtacgc
    15601 tatgacgaga atgtgatgaa caagcatctt tctatgctgg caggcagtca ggcattacag
    15661 gaaatttata aattaatgag taaaagtatt catgagcacc atcaattatg atctatcccg
    15721 catcaaagcg ctggcttttg atgttgacgg agtattgagt tcgacaacag tcccgttgca
    15781 tccttccgga gaaccgatgc gtacggtgaa tattaaagac ggttatgcca ttcagctggc
    15841 agtaaagaaa ggactccata ttgctatcat taccggtgga cggacagaag cggtacgtat
    15901 ccggtttgca gcattgggtg tgaaggatct gtatatgggg tctgcagtga aaattcatga
    15961 ttaccgtgat ttccgcgata aatacggtct gtctgatgac gaaattctgt atatgggcga
    16021 tgatgtgcct gatatagaag tgatgcgtga gtgtgggttg ccttgttgtc ccaaagatgc
    16081 agttccggaa gttaagtcgg ttgcgaagta tatatcttat gccgatggcg gtcatggctg
    16141 tggacgtgat gtggtggaac aagtattgaa agctcatggt aagtggatgg cggaagatgc
    16201 tttcggctgg tgagttgtaa atcactaaat gataaataaa actatgcttg gaaatttaga
    16261 taaatatcag attatattag cctccaattc tccccgccgg aaagaactga tgtcaggctt
    16321 gggag
//
