LOCUS       gnlProkkaHNDMMMFM_404  10598 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HNDMMMFM_404.
ACCESSION   gnlProkkaHNDMMMFM_404
VERSION     gnlProkkaHNDMMMFM_404
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 19:13:52
            Original ID  :: gnl|Prokka|HNDMMMFM_404
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10598
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10598
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1284:5598]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1285..5598
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..10598
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10598
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             73..1221
                     /locus_tag="ctg404_1"
                     /transl_table=11
                     /translation="MIEKQSYQEPFSEVDKRKDDEMEIDLMAIFYKIITVRGVLCKAAG
                     VGVIIAIVVALSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSASKKDDKMTLESYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVLFGKSLLASLRKELKNKEIEQDK"
     CDS             1285..2004
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 56.8; E-value:
                     3.3e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg404_2"
                     /sec_met_domain="NTP_transf_3 (E-value: 6.8e-17, bitscore:
                     52.2, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CGIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLITPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             2025..3326
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 209;
                     E-value: 1.4e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg404_3"
                     /sec_met_domain="CTP_transf_like (E-value: 2.3e-13,
                     bitscore: 40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 9.7e-122, bitscore:
                     395.5, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.2e-63, bitscore:
                     204.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKTILENERALEVRELCMPIKEILELIPGTK"
     CDS             3343..4467
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 58.1;
                     E-value: 1.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg404_4"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.3e-20, bitscore:
                     63.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.1e-20, bitscore:
                     64.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIVRGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     CDS             4477..5598
                     /NRPS_PKS="Domain: Aminotran_5 (30-366). E-value: 2.4e-34.
                     Score: 110.7. Matches aSDomain:
                     nrpspksdomains_ctg404_5_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 75.9; E-value:
                     4.9e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg404_5"
                     /sec_met_domain="Aminotran_5 (E-value: 1.8e-31, bitscore:
                     99.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPKDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKVSKKYPKR
                     SYYCNLYLQYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFR
                     ICALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     aSDomain        4567..5574
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg404_5_Aminotran_5.1"
                     /evalue="2.40E-34"
                     /label="ctg404_5_Aminotran_5.1"
                     /locus_tag="ctg404_5"
                     /protein_end="366"
                     /protein_start="30"
                     /score="110.7"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICL
                     NSLLPKDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDI
                     AMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASA
                     QKGLQAMTGLSFIIGNEEQIKVSKKYPKRSYYCNLYLQYENFERTGEMHFTPPVQTIYA
                     TRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPN
                     WDFEKIHDYCYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLKAALNHY"
     CDS             5595..5738
                     /locus_tag="ctg404_6"
                     /transl_table=11
                     /translation="MIAEILLKIRHFYFSLRGIHFHPESVISGVPIRSFRLVGKYGNIN
                     LR"
     CDS             5941..7425
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg404_7"
                     /sec_met_domain="Polysacc_synt (E-value: 1.6e-31, bitscore:
                     99.7, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENLKQKTVSGIMWSAIERFSLQGVQFIIQIILARLLLPSDYGMI
                     GMLAIFLQVAQVFIDSGFTNALIQKKDRTEEDFATVFYFNILVAVLFYGILFFSASLIA
                     DFYNMPTLVLVIRFIALSLIINALSAIHRTKLIISVNFKTQSKISLGAAFISGVIGIWM
                     AYVGCGVWALVWQTLLNSIILTILFYCLVHWKPLHTFSKSSFERLFNFGSKLLISSLIN
                     TVYRNLYTIVIGKKFSVVELGYYTRAEQFAIFPSNNLNALVSRVAYPILSSIQDDDKCL
                     TNAYRNYIRLSSYIIFPLMVGLLVLANPIISLLLTDKWSGVVILLQILCLDWMFDHLSQ
                     INLNLLWVKGRSDLSLRLEIIKKTIAIFILFVSIPFGLEVMCWGRVIYSLIATYLNTYY
                     TNSLIDLTLKLQVKDVFPSLILSFIMGGIVFICISFFETDIVKIVIGCITGMSFYILLS
                     FLFKLDSFFCILTLIIKTKNIDENIKKDFSSNSKDN"
     CDS             7379..8638
                     /locus_tag="ctg404_8"
                     /transl_table=11
                     /translation="MKILKKIFQVIVKIINHCVPVDSRSLYFIPHPNCRTDKYDIINYS
                     SDNVLVLLNYLLKKDSAEYYKIYVEIYDSSRISEYQEYIYGINPNIRCTFLCACVGRFF
                     FNKVSFKDMLYAFFCFCRASKCFTATFYYDFSFKKRSQQIICLGYYTPFKDDYHMGDHS
                     YDKFRNTTCNSFDYSIATSCLSARIISIDCGISYDKFKVLGFPRNDLLISKNNCNVIKR
                     EISKFAGYDVTKYIVYTPTFRDYETVTEGNLRSILGYVDCDLLKLSKILLKFNAALILK
                     LHPLQNKTVLKKDLPKGILVFEQTYKYGLYDLLSFSDGMITDYTSTYFDFLLVNKPVIF
                     NFYDIEEYRRVRGFSFEPIEFFCAGDIVYNYNELIDAVMGLLAGKDIHAEHRRHISLLM
                     NQFQDDNSTKRICDIFLNEI"
     CDS             8647..9396
                     /locus_tag="ctg404_9"
                     /transl_table=11
                     /translation="MNYAFVVQARLGSTRLPGKILKPFYGNQSILDLMVHKLSAISNIP
                     VIIATTNSVINEPIEKKALALGVKCFRGEENDVLKRFIDVAEYFDIQGIFRICSDNPFL
                     DVHAARQLVEIAMKSCNDYISFDIDGTPSIKTHFGFWGEFVTLDALKRVIGFTDDLLYR
                     EHVTNYIYSHPELFNIQWISGSPVVSKHHNIRLTIDTLEDFSVAQRIYRDLQEKRVEIS
                     IEVIVDYVRRHAEYIQLMKQQIKKNSK"
     CDS             9396..10436
                     /locus_tag="ctg404_10"
                     /transl_table=11
                     /translation="MKNTYIIGEIGQNHNGSVDLAKLIIELISRPVHEDVFGMDFMPMN
                     AVKMTKRDLSEELAVSQMNQIYDNPNSFGRTYGEHRAFLELDDQAHFEIYKYAKSLGLD
                     FIETLCAKGCLSLLKLFTPDRLKVASRDLTNLPLLEALAETHIPIILSTGMAGQRELDN
                     ALDVITRYHSNIAILHCVSQYPTHPNNLNLRTITYLKKHYNKFEIGFSDHTIGISAATA
                     AVAMGAEIIEKHVTIDRHMKGTDQLGSLGPDGVNRMIRDIRIAECWLGTEDLYIEKGVE
                     KSKIKLERSIATRKYIPAGSIIQESDIHLLSPGDGYKWIDKKNVIGHFAKQDISANEII
                     YPDFIE"
ORIGIN
        1 ctacttcctt cagttctttg ggtatgatga ttgcttctat tgctaatttg ataaagaaat
       61 aaatgaccta ttatgattga aaagcaatct tatcaagaac cgttttctga agtggataaa
      121 aggaaagatg atgaaatgga aatagacttg atggctattt tttataagat tattactgtt
      181 cgtggagtac tatgcaaagc tgctggagtg ggagtaataa ttgctatagt ggtggcattg
      241 agcattccca agcaatatac agtaaaggtt accctttctc ctgaaatggg caatgcgaag
      301 ggaagtaatg gtttagccgg acttgctgcc tcgtttttag gagatggggc tctaataggg
      361 gaaagcacag atgccttgaa cgcttctctt tcagcagata ttgtttcttc aactcctttt
      421 ttattggaac ttttagaaat ggaagtctcc gcttctaaaa aggatgataa aatgactttg
      481 gagtcttatc tcgatgaaga gtcatctcct tggtgggatt atcttatagg ttttccgggc
      541 atagtaatag gaggagttaa atcattattc ggagaagata cggttcctgc cagtggaggg
      601 cggcaaggaa ctatcgaatt gacgaaagaa gtaaatgaga agattaattt tcttaaaaag
      661 aagattagtg catccattga taagaaaacc gccataacga gcattactgt caccttacaa
      721 aatccgcaga tcactgcggt tatagcagat tctgtcgttc ataaattaca ggaatatatt
      781 attgggtatc gaacttcaaa agtaaaagaa gactgtgcgt atttggaacg gttgtttaaa
      841 gaacgtcagc aggaatatta tgctgctcaa agaaaatatg cggattatgt agacgcccat
      901 gataatgtgg ttcttcaaag tgtacgtgct gagcaggagc gtttacagaa cgacatgagt
      961 ttggcttatc agatatatag tcaggttgct aatcagttgc aggtatccag agccaaagta
     1021 caggaggaaa agccagtctt tgcagtagtt gagcctgccg ttgtaccttt gaaaccttca
     1081 ggtatgggac tcaaaattta tattttatta tttgtgttcc tgtccgtatc tggtactctc
     1141 gtgtgggtgc tttttggcaa aagtctgctg gctagcttga gaaaagagct gaaaaataag
     1201 gagatagaac aggataaatg atgctaaaac gtcgtttaca acattcttac atcaattaaa
     1261 ttcacttact atattattaa acgaatgata cgtacagcta tgataatggc tgcgggcatg
     1321 ggaacccgtt ttggccaata tacagaattg atacctaaag ggttcgtcaa agtgggaggt
     1381 attccaatga tagttcgttc tattgatact ttgttatcat gtggcattga gcgaattgta
     1441 atcggtacag gatataaaca agaagtttat gaagaattga agacagacta tcctatgctt
     1501 gaaacctgtt ttagtcctcg ttatgctgaa acaaatagta tgtatacttt atataatacg
     1561 cgggagattc tgggcaatga tgatttttta ttgttagagt cagatttgat ttttgagaaa
     1621 caagcaataa tgagcttatt ggagtgtcct gcggcagatg caatgctaat aactccagtg
     1681 acaaagtttc aagatcagta ttatgtggaa catgatgata attttcgcct ttcttcatgt
     1741 tctgtcaata agaataaact aaacgctaaa ggcgaattgg tcggcatcca taaactatcc
     1801 ggttcctttt acaaaataat gtgtgctgat tatgcgagta ttgttgatga acaacccaat
     1861 ttgggatatg agtatgaatt actacgaata tcttgttctc aatctcctgt ttatgtgcat
     1921 aaagtagaag ggctgaaatg gtatgaaatc gatgacatat cagatttgga atatgcagag
     1981 aaatatattg ttccgtattg ttaattaaaa taatatatca aattatgagt aagacagttt
     2041 atattgggat gactgcggat attatgcatc caggacttat ccgcattatt aatgaggcta
     2101 ctaaatacgg tgatgttata attggtcttc ttacagataa agctattgcg gagcataaac
     2161 gccttcctta tctgacctat gaacaacgaa aagaggtagt tcagaatatt aaaggcgtat
     2221 gtaaagttgt tcctcaagaa gaatggagct atgttgagaa tctcaaacgc attaaacctg
     2281 actatataat tcatggtgac gactggaaaa ccgggccttt acgtgaagaa cgtgtgcgcg
     2341 tatttgaagt gatgaatgaa cagggaggaa aggttatcga aattccatat actttgggaa
     2401 ttaattcatc ttctttggat aaagatatta aggctatagg tacaaccccc gatgtacgtt
     2461 taaaatcact tcgtcgtttg ataaatgcca aacccgtagt tcgtattttg gaggctcatg
     2521 atggactatg tggcttgata attgaaaatc aggaaatatt aaaaggggat aagagggaag
     2581 tatttgacgg aatgtggtct agtagcctta cggattcaac cagtaaaggt aaacctgata
     2641 ttgaggcggt tgatttaact acccgattgc aagatttgaa taatattctg gagtgtacta
     2701 ctaaacctat tatttttgat ggagatacag gtggtaaaat tgaacatttc gtatttacag
     2761 tacgcacttt agaacgtcat ggaatttcag ctataataat tgaagataaa gttggattaa
     2821 aaaagaattc attgtttggt acggatgtta ttcaaactca agatacaatc gaaggtttct
     2881 gcaataagat caaagcagga aaggcatctc agattactga tgattttatg attatcgctc
     2941 gtattgagag ccttatagcg ggaaagccgg taagtgatgc tttagagaga gcttttgcat
     3001 atgtccaagc gggagcggac ggtattatga tacatagcaa aaataagtcg ggtgaagata
     3061 taaaagaatt ttgtttggcg tttcgaaaac agtatgctca tgtacctatc gtggttgtgc
     3121 ctactacata tgatcatatt tatgagtctg aattgtgtga ttggggtgtg aatataatta
     3181 tttatgctaa tcatatgctt cgtgccgctt atcctgctat gatgaatgtc gcaaagacaa
     3241 tattagagaa tgaacgtgct ttagaggtgc gcgaactgtg tatgcccata aaagaaatat
     3301 tggaactgat tccaggtact aaataaaaag aggaatatca ttatgttaag cgtagaaaaa
     3361 gtttatgaaa cgtttctgag tcatgacgtt gattttttta caggagttcc agactcatta
     3421 ctaaaaaata tttgtgccta tatcacagac catacttcac gtgagaaaca tatcatagct
     3481 gctaatgaag gtgcggctgt aggaattgct tcaggttatt atatggcatc aggtaaggtt
     3541 cctgtggttt atatgcaaaa ttccggcttg ggtaatactg ttaatcctct gctgtctctt
     3601 gcagatgaac aagtatacag ttttccaatg cttttgatga ttggctggcg tggtgaaccg
     3661 ggaacaaaag atgaacctca gcataaaaaa cagggtgagg taactttaga tttgttgaaa
     3721 gcaatgcgga ttccttatat aattcttgat tcaaatgaga atgatgcatt tattcagctc
     3781 catgatatca tacaatcagc aaaaactaag aatattcctc atgcaataat tattcggaaa
     3841 gatgtttttg gcaaatataa acttcaaaaa gaattcggat gtaattatcc tttatctcgt
     3901 gaggatgctt tgcaaatagt tgtggattat ctgcctgaaa attcagtggt cgtttctact
     3961 actggcaagc tttctcgtga gttatttgaa tatcgagaaa tgaaagagca aggtcatgaa
     4021 catgattttc tcacggtagg ctctatggga catagttcat caatctcttt gggtattgct
     4081 atagcaaagc aagatagacc tgtttattgc ttggatggtg atggagcatt tattatgcat
     4141 ttaggggcaa ttagtaacat tggcgattta tctcctaaaa actattatca tattttgttt
     4201 aacaatggtg ctcacgagtc tgtaggagga cagcctactt taggatttag tttagatatt
     4261 ccggctattg tccgggggag cggatataag catacttata ctgtttgtac aaaagttgaa
     4321 attgaagaag caatgaagca gcttccaaag ttatgtggtc ctgttttgtt ggaaataaag
     4381 gttaaaatag attctcggga gaatttggga cgtcccacga ctactcctat agagaataag
     4441 gagcatttta tggatttttt aaaataaata tattcgatga aaatagaaag aaaaatatta
     4501 ttaaatcctg ggcctgccac tactactgac agtgtaaaaa tggcacaagt tgttccggat
     4561 atttgtcctc gcgagaaaga attcgcaggt atgatgaaac aacttcggga cgatttggtc
     4621 agagttgctc atgggaattt ggaaaaacat acagctgtat tattttgtgg ctcaggaacc
     4681 atcaatattg atatatgtct aaattctctt cttcctaaag acaaaagggt gcttatagtg
     4741 aataatgggg catatagtac ccgtgctgta gaagtgtgtc aatattatgg tttgcctcat
     4801 attaatttgg aattttctgt ttatgaacgt cctgatttat cggtagtgga aaatgtgtta
     4861 caagaaaatc ctgatatagc tatggtttat actactcatc acgagacggg tacaggaatt
     4921 ctgaacccta ttcgcgagat gggcgctata gctcataaat atcaggctaa atttgtcgtc
     4981 gatactactt cttctttggg catgattcct tttgatatag agaaagataa tgtagatttt
     5041 tgtatggcat ctgctcaaaa aggacttcaa gcgatgacag gtctttcttt tattataggc
     5101 aatgaggaac agattaaggt ttcaaaaaaa tatcccaagc gttcttacta ttgtaatctt
     5161 tatttgcagt atgagaattt tgagagaaca ggtgaaatgc attttactcc accggtacaa
     5221 actatttacg ccactcgtca ggcattaaat gaatattttg aagtgggtga agaagctaag
     5281 tttgcccgtc acaaaagagt ttttgaggct attcattcag gtataaatga aattggtctt
     5341 aaaagtgtaa taaagcgtga atggcagtca ggactggttg tctcagttca atacccagaa
     5401 gatcccaact gggattttga gaaaatacat gattattgtt atgagcgtgg atttacgatt
     5461 tatccaggta agatatcaac tgaggatact tttagaatct gtgctttagg agagatagaa
     5521 gtagatgata ttgagaactt ctttaaagta ctaaaagctg cattaaatca ttataacgtc
     5581 acattaccga tgtcatgatt gcagaaatat tattgaagat tcgtcatttt tatttttccc
     5641 ttcgtggtat acacttccat ccggaaagtg ttatttctgg agtgcctatt cgtagctttc
     5701 gcttagtagg caaatatggc aatattaatt tgaggtgatg cattaggagt tctttattct
     5761 tataaaaagg catcggtagt tataggagat aatgtttgtg tagggtaatt tgcttttagt
     5821 gggagagacc atattagaat tgcggtaagg ggcgaagaag ataataacca attagtgaga
     5881 atattggaaa aatataattg atatcggtaa atgtagttgt ttttatactg tatttaagta
     5941 atggaaaatc taaagcagaa aactgtatca ggaataatgt ggagcgctat agaacgtttc
     6001 tctttacaag gagtacagtt tataattcaa ataatattag ctcgtttgtt actaccatcg
     6061 gattatggta tgatcgggat gttagctatt tttcttcaag tcgctcaagt atttatagat
     6121 agcggtttta caaatgcttt aatccagaaa aaagatagaa ctgaagagga ttttgccact
     6181 gtcttttatt ttaatattct tgtcgcagta ttattctatg gtatattgtt tttttcggct
     6241 tctttgattg cagactttta taatatgccg actttagttc ttgtaattcg ttttatagca
     6301 ttgtcgttga taataaatgc tttatcggct attcacagaa cgaaattaat tatttctgta
     6361 aactttaaaa ctcaatctaa aatttcatta ggtgcagctt ttatatcagg cgtgattgga
     6421 atatggatgg cttatgtcgg ttgcggggtt tgggctttag tttggcaaac tctcttaaat
     6481 agtataattt tgacaatttt gttttactgt ttagttcatt ggaaaccttt acatactttc
     6541 tccaaaagtt cttttgaaag attattcaat ttcggatcta aattattgat ctcaagtctt
     6601 atcaatacag tatatcgtaa tctgtatacc attgtaatag gaaaaaagtt ttctgttgta
     6661 gagcttggtt actatacaag agcagaacaa tttgctattt ttccttccaa taatttaaat
     6721 gctttagttt ctagagtagc gtatcctatt ttaagttcca ttcaagatga tgataaatgt
     6781 ttaacaaacg catatcgaaa ttatatcaga ttatcctcat atataatttt tcctttaatg
     6841 gtaggtttac ttgttttggc taatcctatt attagtctat tgttaacaga taaatggtct
     6901 ggggttgtta ttcttttaca gatattatgt ttggattgga tgtttgatca tttgagccaa
     6961 attaatttga atttattatg ggttaaagga agatctgatc tgtcgttacg tcttgaaata
     7021 ataaaaaaga cgattgctat attcattctt tttgtgtcaa ttccatttgg gcttgaggtg
     7081 atgtgttggg gtagagttat ttactctctg atagcgacat atttgaatac atattatact
     7141 aattctctta ttgatttgac cttaaagttg caagttaaag atgtatttcc aagtttaata
     7201 ctctctttca taatgggggg gatcgttttt atatgtattt ctttctttga aactgatata
     7261 gtaaaaattg tgattggatg tattactggg atgtcctttt atattttact ttcttttctt
     7321 tttaagctag attctttttt ttgtatttta acattgatca ttaaaactaa aaacatagat
     7381 gaaaatatta aaaaagattt ttcaagtaat agtaaagata attaaccatt gtgtgccagt
     7441 tgatagtaga tcattgtatt ttattcctca tcctaattgt agaacagata aatatgatat
     7501 tataaattat tcgtcagata atgttctcgt tctgttaaat tatttgctaa aaaaagatag
     7561 tgctgaatat tataaaatat atgttgaaat ttatgattct tctcgtattt cagaatatca
     7621 agaatatatt tatggcataa atcctaatat taggtgtact tttttatgtg catgtgttgg
     7681 acgttttttc tttaataaag tatcttttaa ggatatgttg tatgcctttt tttgtttttg
     7741 tagagcaagt aaatgtttta cagctacttt ttattatgat ttttcattta aaaaacgctc
     7801 tcaacagatt atttgtttgg ggtattatac tccattcaaa gatgattatc atatgggaga
     7861 tcattcttat gataaatttc gtaatacaac atgtaactca tttgattact ctattgctac
     7921 ttcttgttta agtgctagaa taatttcaat agattgtgga atctcatatg ataaattcaa
     7981 agtcttagga tttcccagaa atgatttgtt gatatcgaaa aataattgca atgttattaa
     8041 aagagaaatt tcgaaatttg cgggatatga tgtaactaaa tatatagttt atactccaac
     8101 ttttcgtgat tatgagactg ttactgaagg taatttgcgt tcaatactcg gatatgttga
     8161 ttgtgatttg ttgaagttat cgaaaatact attgaagttt aatgcggctt taattcttaa
     8221 attacatcct ttgcagaata aaacagtctt aaaaaaagat ttacccaaag gtatacttgt
     8281 ttttgaacaa acatataaat atggattgta tgatcttttg tcattttcag atggaatgat
     8341 tactgattat acttctacct attttgattt tttattggta aataagccag tcatatttaa
     8401 tttctacgat attgaagaat atcgtagagt aagaggtttc tcatttgagc caatagaatt
     8461 tttttgtgca ggtgatattg tttacaatta taatgaattg atagatgctg tgatgggact
     8521 tctggctggg aaagatattc atgctgaaca tcgacgtcat atttctttat tgatgaatca
     8581 atttcaagat gataattcaa caaagagaat atgtgacata tttttaaatg aaatataata
     8641 aataaaatga attatgcatt tgtggtgcag gcacgtttag gttctacacg tttgcctgga
     8701 aaaatattga aacctttcta tggtaatcaa tcgattcttg acttaatggt tcataagctt
     8761 tctgctatat cgaatattcc agtaattatt gctacaacaa attctgttat caatgaacct
     8821 attgaaaaga aggcacttgc attaggggta aagtgcttca gaggtgagga gaatgatgtt
     8881 ttaaaacgat tcattgatgt tgctgaatat tttgatatac agggtatatt ccgaatatgt
     8941 tctgataatc catttttaga tgtacatgcg gcaaggcaat tggtcgaaat agcaatgaaa
     9001 tcttgtaacg attatataag ttttgatatt gatggtactc catcaattaa aactcatttc
     9061 ggtttttggg gagaatttgt aacgcttgat gcgctgaagc gagttatagg atttactgat
     9121 gatttattgt atcgtgaaca tgttactaat tatatatata gtcatcctga actttttaat
     9181 attcaatgga tttcaggatc tccagtcgtg tcaaaacatc ataatattcg actcacgatt
     9241 gatacgttag aagatttttc tgtagcacag agaatatata gggatttaca agaaaaaaga
     9301 gtggaaatat cgatagaagt gattgtagac tatgttcgaa gacatgcaga atacattcaa
     9361 ctgatgaaac aacaaataaa aaaaaattct aaataatgaa gaatacttat attattggtg
     9421 aaatagggca gaatcataat ggttctgttg acttggctaa gttgattatt gaattaatct
     9481 cacgacctgt acatgaggat gtttttggta tggatttcat gccaatgaat gctgttaaaa
     9541 tgactaaaag agatttatca gaagaattgg ctgtttctca aatgaatcaa atatatgaca
     9601 atcctaattc ttttgggcgt acttatggtg aacatcgtgc ttttcttgag cttgatgatc
     9661 aagcgcattt tgagatttat aaatatgcta agtcattagg attagatttt atcgagacgt
     9721 tatgtgccaa aggatgtctg tctttgctta aactgttcac accggatagg ctaaaagttg
     9781 ctagtcgtga tttgactaac ttaccattgc ttgaagcatt agcagaaact catattccta
     9841 ttatattatc gacaggaatg gctggtcaaa gagaacttga caatgcatta gatgtgataa
     9901 cgagatatca tagtaatata gctattctac attgtgtatc tcagtatcca actcatccaa
     9961 ataatttgaa tctacgtaca ataacatatt tgaagaagca ttacaataag tttgagatag
    10021 gtttttctga tcatacaata ggtatttctg ctgctacagc tgctgtagcg atgggagcgg
    10081 aaattataga aaagcatgta acaattgatc ggcatatgaa aggaacagac cagcttggct
    10141 ctttaggtcc agatggggtt aatcgtatga ttcgagatat tcgcatagca gagtgttggc
    10201 ttggtactga agatctttat atagaaaaag gtgtggagaa gtctaagata aaacttgaac
    10261 gttctattgc cactcgaaaa tatattccag caggtagtat tattcaagag tcggacattc
    10321 atttactgag tcctggtgat ggttataaat ggatagataa aaaaaatgta attggtcatt
    10381 ttgctaaaca agatatatca gcgaatgaaa taatatatcc tgattttatt gaatagatat
    10441 attcctactg caacttgtat tacggtatag agtactgcct gctataagct aagtagtgat
    10501 taataaataa gggtaaaata ctaaaaaaat gaaagagata aagcttatac ttacagatat
    10561 tgatggcgtt tggactgatg gcggaatgtt ttatgatc
//
