LOCUS       c00057_gnlPro..        13158 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AKIJKAMB_57.
ACCESSION   c00057_gnlPro..
VERSION     c00057_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 01:41:19
            Original ID  :: gnl|Prokka|AKIJKAMB_57
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13158
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13158
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:3298](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2..3298
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..13158
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13158
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             2..3298
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg57_1"
                     /sec_met_domain="PFOR_II (E-value: 4.5e-19, bitscore: 58.0,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 3e-55, bitscore: 176.7,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 7.8e-32, bitscore: 100.0,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.1e-12, bitscore:
                     37.3, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 1.9e-12, bitscore: 37.4,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 3.5e-08, bitscore: 22.5,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.9e-05, bitscore: 14.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 9e-26, bitscore: 78.9,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="ASQGLLLMIPNMYKIAGEFLPCVFHVSARTLASHALCIFGDHQDV
                     MSARQTGFAMLAEGSVQEVMDLAGVAHLSTIKSRVPFMNFFDGFRTSHEIQKIEMLEND
                     DLAPLIDQEALAEFRARALNPMKPVARGMAENPDHFFQHRESCNNYYEAVPAIVEEYMN
                     EISKITGRKYGLFDYYGAEDAERVIIAMGSVTEAAREAIDYLVANGEKVGMVAVHLYRP
                     FSAKHFLAAVPKTAKTIAVLDRTKEPGANGEPLYLDVKDCFYGAENAPVIVGGRYGLGS
                     KDTTPAQILSVFENLAMPMPKNHFTIGIVDDVTFTSLPQKEEIALGGEGMFEAKFYGLG
                     ADGTVGANKNSVKIIGDNTDKHCQAYFSYDSKKSGGFTCSHLRFGDNPIRSTYLVNTPN
                     FVACHVQAYLHMYDVTRGLRKNGSFLLNTIWEGEELAKNLPNKVKKYFAQNNISVYYIN
                     ATQIAMEIGLGNRTNTILQSAFFRITGVIPVDQAVEQMKKFIVKSYGKKGEDVVNKNYA
                     AVDRGGEYKTLTVDPAWANLPDDAKAENNDPAFINEVVRPINAQDGDLLPVSAFKGIED
                     GTWYQGTSKYEKRGVAAFVPEWNAENCIQCNKCAYVCPHASIRPFVLDAEEQKGAKFEQ
                     LKAVGKAFDGMTFRIQVDVLDCLGCGNCADICPGNPKKGGKALTMKHLESQLAEADNWT
                     YCAENVKSKQHLVDIKANVKNSQFATPLFEFSGACSGCGETPYVKLISQLFGDREMVAN
                     ATGCSSIYSGSVPSTPYTMNEKGHGPAWANSLFEDFCEFGLGMELANEKMRARLVKVMN
                     EAIASDCCPAEYKEVFAEWINNMLDAEKTKELAEKIIPMVEAAKDKCNHCKQIADLQQY
                     LVKRSQWIIGGDGASYDIGYGGLDHVIASGKDVNILVLDTEVYSNTGGQSSKATPVGAI
                     AKFAAAGKRVRKKDLGLMATTYGYVYVAQIAMGADQAQTLKAIREAEAYPGPSLIIAYA
                     PCINHGLKAGMGKSQEEEEKAVKCGYWHLWRYNPALEEEGKNPFQLDSKEPNWEDFQGF
                     LKGEVRYASVMKQYPAEAEELFKAAEENAKWRYNSYKRLARENWGADTAE"
     CDS             3423..3611
                     /locus_tag="ctg57_2"
                     /transl_table=11
                     /translation="MIGFVIWIIGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(3622..4482)
                     /locus_tag="ctg57_3"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVVPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNTESIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPEKD"
     CDS             complement(4510..5340)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg57_4"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.3e-29, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             complement(5337..6563)
                     /locus_tag="ctg57_5"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKGEREQKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             7036..8322
                     /locus_tag="ctg57_6"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFIRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RYFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFMAIFTLPQQFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLLIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVTMGIVLLALPLIKIAPADLLPYYEEWCHSLAVHQSTGAYDSFFYARP
                     IAVWTLPHFRALQIGMLGLLTLLFLGNFRKWSSFAFRAQALGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTATDKILFWCCFVLLCIVPIDIFVPVPIRDFITRTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             complement(8285..8617)
                     /locus_tag="ctg57_7"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGVPQ
                     CSRMVGRALKEVPDELSIPCHRVVNTAGRLVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(8645..11398)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 64.3; E-value: 4.2e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg57_8"
                     /sec_met_domain="Peripla_BP_1 (E-value: 6.1e-21, bitscore:
                     64.3, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTMRYLKWMLVLFCLIGMTACRQDTPRFRIGVAQCSDDSWRHKM
                     NDEILREAMFYNGVSVEIRSAGDDNSKQAEDVHYFMDEGVDLLIISANEAAPMTPIVEE
                     AYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGLSGST
                     PAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRRHPKIDAVYAHNDRIA
                     PGAYQAAKMAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQLAMDI
                     LEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVATQQVV
                     LYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDKLEEQRDQLIQLSHQ
                     LEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADKTLSGDQHRMLMLIQRNVNILLR
                     LVNQILDFRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDSMPDTDYHT
                     LADMEKLERIYFNLLSNAFKFTPENGKIAIRLSSLSKEDKRWIRFTVANTGSMISAEHI
                     RNVFDRFYKIDMHHTGSGIGLALVKAFVEMHGGMISVESDEKQGTVFTVELPVQSCEAV
                     AAEPDTTLVSADSRTTDVLLAEEEELEKGYDSSKSSVLIIDDNEDIRSYVHTLLHTDYT
                     VIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLTACSL
                     DEQRIQGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDK
                     DFVERFKSLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKA
                     ASLLASSDMTVAEIGYEVGFSSPSYFAKCYKEQFGESPTDFLKRKG"
     CDS             complement(11731..12849)
                     /locus_tag="ctg57_9"
                     /transl_table=11
                     /translation="MKHISNFLRSKSWNVFLFLYLALPLFAQKEYKIDQVSVVNVGDGR
                     LLFRELKTEKALNGEHRIIDGYHSAYVLASFKDGFYDGGYKEYVDNILITEGSYKEGRK
                     DGLFKINSKFDGKLKEEKSYKEGKLDGTSKSYFTTGKVESERNFRMGKEHGKQLSYESD
                     GTLRKEHNYKDGKQVGKQYTFLKGTYDLYETVYFNEEGLQDGEYSSVFTFGSPRILGSY
                     KNGKKNGRWTTFAESGDTLMIETYLDGKEDGLHVSFANGSGVRQKEYYMKNDRKDGLYR
                     EYNLENGELRYEATYQAGRLHGKERRLIVSNRFDYWETSTYVNGRQNGPFEARYVKNDQ
                     LRECGEYKNGRRVGRWKRYTIDGKLEKEWDEN"
ORIGIN
        1 tgcttctcag ggtcttctcc tgatgatccc taacatgtac aaaattgccg gtgaattctt
       61 gccatgcgta ttccatgtat cagcgcgtac attggcttct cacgcattgt gtatcttcgg
      121 tgaccatcag gatgtaatgt cagctcgtca gactggcttt gctatgttgg ctgaaggttc
      181 tgtacaggaa gttatggatt tggccggtgt tgctcacctg tctactatca agtcacgcgt
      241 tcctttcatg aacttcttcg atggtttccg tacttctcac gaaatccaga agatcgaaat
      301 gttggaaaac gacgacctcg ctccgctgat cgaccaggaa gctttggctg aattccgtgc
      361 ccgtgcactg aatccgatga agccggttgc ccgtggtatg gctgaaaacc ccgaccactt
      421 cttccaacat cgtgaatcat gcaacaacta ctatgaagca gttcccgcta tcgtagaaga
      481 atacatgaat gaaatttcta agattacagg tcgcaaatac ggtttgtttg attactacgg
      541 agcagaagat gcagaacgcg taattatcgc tatgggttct gtaacagaag ctgcccgcga
      601 agctatcgac tacttggtag caaacggcga aaaagtgggt atggttgccg tacacttgta
      661 tcgtccgttc tctgctaaac acttcctggc tgctgtacct aagactgcta aaactatcgc
      721 agttcttgac cgtactaaag aaccgggtgc taacggcgaa cctctttacc ttgacgttaa
      781 agactgcttc tacggtgcag aaaatgctcc ggttatcgtt ggcggtcgct acggtttggg
      841 ttcaaaagat actactcctg ctcaaatcct ttcagtattc gaaaacttgg ctatgccaat
      901 gccgaagaac cacttcacta tcggtatcgt agacgacgtt actttcactt ctcttcctca
      961 aaaagaagaa atcgctttag gcggcgaagg tatgttcgaa gctaaattct acggtttggg
     1021 tgctgacggt acagtaggtg ctaacaagaa ctctgtaaag attatcggtg acaacactga
     1081 caaacactgc caggcttact tctcttatga ctctaagaag tcgggcggtt tcacttgttc
     1141 tcacttgcgt ttcggtgaca atccaatccg ttctacttat ctggtaaata ctccgaactt
     1201 cgttgcttgt cacgttcagg cttacctgca catgtacgac gtaacacgtg gtttgcgtaa
     1261 gaacggttct ttcttgctga acaccatctg ggaaggcgaa gaactggcta agaacctgcc
     1321 taacaaggtg aagaaatact ttgcacagaa caacatctct gtatactata tcaacgcaac
     1381 tcagattgca atggaaattg gtttgggcaa ccgtaccaat acaatccttc agtctgcatt
     1441 cttccgtatc acaggcgtaa tccctgtaga tcaagctgtt gaacagatga agaaattcat
     1501 cgttaagtct tacggcaaga agggtgaaga cgttgtaaac aagaactatg ctgctgtaga
     1561 ccgcggtggt gaatacaaga ctctaactgt tgatcctgct tgggctaacc tgccggatga
     1621 tgcaaaagca gaaaacaatg atcctgcttt catcaacgaa gtagttcgtc cgatcaatgc
     1681 acaggacggt gacttgctgc cggtatctgc attcaagggt atcgaagacg gtacttggta
     1741 tcaaggtact tccaaatacg aaaaacgtgg tgtagctgca ttcgttcccg aatggaatgc
     1801 tgaaaactgt attcagtgta acaagtgtgc ttacgtttgt cctcacgctt ctatccgtcc
     1861 gttcgtactc gatgctgaag agcagaaggg tgctaagttc gagcaactga aagctgtagg
     1921 taaagcattc gatggtatga cattccgtat tcaggtagac gttctcgact gtctgggttg
     1981 cggtaactgt gccgacatct gtccgggtaa tccgaagaag ggtggcaagg cattgaccat
     2041 gaaacacctt gaaagccagt tggccgaagc tgataactgg acttactgcg ctgaaaacgt
     2101 gaagagcaaa caacacctgg tagacatcaa ggctaacgtg aagaactctc agttcgcaac
     2161 tccgttgttt gagttctcag gcgcttgctc cggttgtggt gaaactccgt acgtgaaact
     2221 gatttctcag ttgttcggtg accgtgaaat ggttgctaac gctacaggat gttcttctat
     2281 ctactccggt tcagttcctt ctactccgta cactatgaac gaaaagggtc acggtcctgc
     2341 atgggctaac tccttgttcg aagacttctg tgaatttggt ctgggtatgg aactggctaa
     2401 cgaaaagatg cgtgcccgtc tggtgaaagt aatgaacgaa gctatcgctt ctgattgctg
     2461 cccggctgaa tacaaagaag tatttgctga atggatcaac aatatgctgg atgcagaaaa
     2521 gactaaggaa ctggccgaaa agatcattcc gatggtagaa gctgctaaag ataaatgcaa
     2581 ccactgcaag caaatcgctg atctgcaaca atatcttgtt aaacgcagcc aatggatcat
     2641 cggtggtgac ggtgcttctt atgatatcgg ttacggtggt cttgaccatg taatcgcttc
     2701 cggtaaggac gttaacatcc ttgtattgga tactgaggtt tactctaaca caggtggtca
     2761 gtcttctaaa gctactccgg taggcgctat cgctaagttt gctgctgcag gtaagcgtgt
     2821 acgtaagaaa gacctcggtc tgatggctac tacttacggt tatgtatatg ttgctcagat
     2881 tgctatgggt gctgaccagg ctcaaactct gaaagctatc cgcgaagcag aagcatatcc
     2941 cggaccatct ttgattatcg cttacgctcc gtgtatcaac cacggtctga aagccggtat
     3001 gggtaagagc caggaagaag aagaaaaggc tgttaagtgc ggttactggc acttgtggcg
     3061 ttacaaccct gctttggaag aagaaggcaa gaacccattc caattggata gcaaagaacc
     3121 gaactgggaa gatttccaag gtttcttgaa gggtgaagtt cgttacgctt ctgtaatgaa
     3181 acaatatcct gctgaagctg aagaactgtt taaagctgct gaagaaaacg ctaaatggcg
     3241 ttacaacagc tacaaacgtc ttgccagaga aaactgggga gctgatacag ctgaataata
     3301 agtagaaata ctttgtacat aataaaaggc aggaattctg gaaacagatt cctgcctttt
     3361 ttgtttatat cttagaagta acgattactt ctcacgaaga tattcattaa aactctaaag
     3421 atatgatcgg atttgttatt tggattatcg gtttgatact gactttcaga gctgccatag
     3481 agatttggaa tataaatgcg gctgtagaga aaagacttat agcgattgta ttaatcgttc
     3541 ttaccagctg gctgggacta cttttctact acttctatgg taaagaaaga atggcgggat
     3601 ggttgaagta gtgtttgcat atcaatcttt ctcaggaatc caactgttca ccagttcctg
     3661 atgttcttcc atccattgac gggcagcctg tctttccgtt gtctgcgcct cttccagagc
     3721 agtcattaag gagctgattt ccgcatctgt cagacgaatg ttgcccaaaa gttcggcagc
     3781 aaaagggtct ttctcgctaa aacctttcca tgctatggta tgaatggatt ccgtatttcc
     3841 atatatcagc ttcgggtcct gaagaacttt cagcttgaaa cggtcgaaca tccagtgagg
     3901 cgtccatccc gtcacgacaa tccagtcttt cttatcaatc gctttcttta gggaagcagt
     3961 catggcaggt ccgctcgaag tcatcagttt ataatccaat ccatagtctt tgatggcctg
     4021 atcggtagct ttcataatac cggctccggc atcaataccg acaatctgac cggagaaacg
     4081 ttccttttcc gcgttcagtt cttcgattga gttgatcgta acgtaatccg gaaccaccag
     4141 cccgatacgg gcaccatcat aaatatcccc gataacttcg agtttatccc cgtattgttt
     4201 catataatct tccatagtga caggcatcca gacatccata aatacgtctg ctttcttacg
     4261 ggagatagag gtaaatatag gtgcaaggtc ggcattcagc aactttacat cgtacccctg
     4321 atcttcaaaa atcgctttgg caaggtttgt cattgcaata ccttccgacc agttggcata
     4381 agcgatactt atcttcttac tctttccgtt gtctccgcag gaaacgaagg ttaagagtat
     4441 gccggcaata aacattgccg caatcatttt tatcttattc attgattatt cctttctttg
     4501 gtgtgattct tatttctttt tactttttct gttatctgcc ataccctgag tgatgcggtc
     4561 cagcacgatc gccaatatca cgactgcgat accgccttca aatccgagtc cgattttcat
     4621 ttgggtgata cctttcagca cgatttctcc caatcctccg gcagaaatca tggcagcaat
     4681 cactaccatc gaaagtgaca tcatgatcgt ctggttgatt cccgtcagaa tagtaggcaa
     4741 cgccaaaggc aattgcacct tataaagaag ctgccaggga gtagctccaa aagagcggga
     4801 ggcttctact acgtttttag gaacctgacg aatgcccaga ccggtcagac gaaccacagg
     4861 aggcattgca aagatgatgg tggcaaaagc tcccggcaca gttcccaatc cgaagaatag
     4921 aacggcagga atcagataga caaaggcagg cattgtctgc ataaagtcga ggacagggcg
     4981 cattatcttg ttacaacgat cactgttggc agtccagatt cccaacggaa cgcctaaaag
     5041 caatgccaga caagtggaag aaagtaccaa tgccaatgtc tgcatcgttt cttcccaaaa
     5101 gcccatgccg taaataagca ataaacccaa gagggtaaat acggctgtcc ccttacccga
     5161 cttaaaccag gcgagcgcag ccagcactgc aattgtgata taaaaaggta ttccaaacag
     5221 tacgtgctga aaaccgtcta tgaatcctcc gatccccatg ctgagagcat caaaaaagga
     5281 agcaaaatgt tctgtgagcc aattaatggc agtctctata tattgtccga tatttatcat
     5341 aattctattg cgttttgaat gatttcatta atttcttctt tatcttttcc cgttacttcg
     5401 atgatcaatg aggaaagtgg cactacgcct tcaaactccc gattctcatt tacgacccag
     5461 attggcgagt tcgtttttgt catcaacgga agaatatctt ccagcaccgt atcacccagc
     5521 actgaatgaa cttcatgcct tactacggac tcgatggagc ggatttgctc ttttcgtagt
     5581 ttcagcaagt cattcaaccg cacctctcct actaacagat tattggaatc gactaccgga
     5641 agaacggtca gattccgttc gcgcatctta cggatcagca cctccgggcc ttctttcttc
     5701 aaacgtgcca ctatgggttt atctaccata acagaggaag ctgttataat cttgcttcga
     5761 tctacattct ccacaaatcg ttctacataa gcgttggcag gttcggtcag gatttcttcc
     5821 gatgtaccga tttgtacaat ttctccatcc ttcatgatag caatccggtc acccaattta
     5881 atcgcttcac tcaggtcgtg agtaataaag acaatcgttt ttttcatctt cgactgcaaa
     5941 gtcagcagtt catcctgcat ctgcacacgg atcaaaggat cgagtgccga gaaggcctca
     6001 tccatcaaca ggacttcggg attattggcc aaagcccgcg ccagcccgac acgctgctgc
     6061 atcccacccg acagttcact taccatctga ttctcgtagc ctttcagccc caccagttgc
     6121 atgctttcca tcgctttctg ctcccgttct ccctttttta ctccctgtag ttcgagcccg
     6181 aaagctatat tatgcaagac agaacggtga ggaagcagac cgaagttctg aaagaccata
     6241 gccagttctt tccggcgaat ctgcaacagt tccttatccg acactttggc tatgtctgtt
     6301 ccattgataa tcacttctcc ggaagtaggg cgtatcaaac ggttgatgca gcggagtaaa
     6361 gtggactttc cactaccgga cagccccata atgacgaata tttcgccttc attaatggaa
     6421 agattcgcat ctttcaccgc aactgtacat ccggtcgctt tcaatatttc actttttgtt
     6481 ttaccttctt tcaacatctt caaagccttc tgcttctcat tgccaaaaac cagatagaga
     6541 tctttaattt ctattttact catacaataa aatggtttag gttattaaaa taatatacac
     6601 agcaagacaa gaacaaacga taacaggaat ctttctttat atcgtataaa gttctgattt
     6661 aaatacggga caaataacaa tgaatcccga aataattaat aaaatgatta ttgacagact
     6721 gagtaattaa aaaaggaata gaatttgata agataatcct ttcaacgaat agcaaaaaat
     6781 agcattttta tgtataaaaa cagcctgttc cagtatcttg ctggcacaaa gatacaaaaa
     6841 acggattaaa catacaaatt atattcaaaa tccggggcat acagagggct ttatttgtaa
     6901 tgatatggaa agtttccggg taatattccc ctatcactca gcaaaataga acaaaccggc
     6961 agataaatat aaaataagtt tgaatatttc acttaaacac cgtatatttg gcgtcaataa
     7021 ctaaactaga tttatatgtt caacagggct attacaattt tcctggggaa ggataattgt
     7081 cattacacaa caaaagaaaa acaaacaggt actgccacac tagacgacaa aagccaagta
     7141 cagttcctta gtaaaaagaa ccccaaaatg ccgtttttct atagccggcg gaatctctac
     7201 atgataggtt tcctgctcgc ttttatagtg actctgctcg aatttatacg aggacggcat
     7261 caaaacttta tggtcttctc ggacgctact caattcttct ggcaaggcat cagcccatac
     7321 acaactgaat ttgtagaagc tcacggacgc tacttccttt attctccagt tttcacggta
     7381 ttgttcgctc cgtttgcgta tctgcctgca tggctgggac ctttcgcgtg gaatctattc
     7441 aattattcgc tgttctttat ggcgatcttc acgctgcccc aacaattcac ccagcagcag
     7501 aaatgccgta tgttcctttt tctgttactg attttaggac aaagtttact ttcatttcag
     7561 tataacataa cggtagccta tttattctta ttcgcctata cgttattgga aaaagaccgt
     7621 ggatttctgg ctgttctgtt aatcatgatt tcgggatgta ccaaagtata tggaattttc
     7681 gaactggcat tgttgctgtg ctatcctcac gtatggcgta actttggcta tgccgttaca
     7741 atgggcattg tattgcttgc attaccgtta atcaaaatag ctcctgcaga tttgctcccc
     7801 tattatgaag aatggtgcca tagtcttgct gttcatcagt ccaccggagc ttatgattca
     7861 tttttctatg cccgccccat tgcagtatgg acattgccac acttccgtgc acttcagata
     7921 ggaatgctcg gcttgctgac tctgctcttt ttggggaatt tccgcaaatg gtcgtctttt
     7981 gccttccgtg cccaggcttt gggcattctc atgggctggg tagtattact gagtgactcc
     8041 gccgagaagc atacctatat tatcgcattg gcaggtttca tgctctggta ttggagcaga
     8101 ccaacacgta ccgcaacaga caagattcta ttttggtgct gttttgtgct gttatgtatc
     8161 gttcctatcg acatattcgt ccctgtaccc atcagagatt tcattaccag gaccttatgg
     8221 cttcatgtat gggttttctt tattgtatgg atacggatga tatggcttac cttccttgca
     8281 tccttcattc atccacgtgc cacaaatgtt ctttcagatt aacgcatccg ttagctttga
     8341 aagaaacttc ttctgccagc aagagttgtt tttgttccac ccaaccgggg accagccttc
     8401 cggcggtatt tacaactcta tggcagggaa tggataattc atccggcact tctttcaatg
     8461 cacgtcccac catacgcgag cattggggta cccccaacaa caaagcaata cctccatagg
     8521 tagatacttt tcccacaggt atctgggata cgacttcgta cacttccttc cgaaaggatt
     8581 cggaaaagct ctctttatct actttataat ctttcatata tccctcttta cgatatcaat
     8641 gaaatcatcc tttccttttc aggaaatctg tcgggctctc tccaaactgc tctttatagc
     8701 acttggcgaa ataagaaggt gaactgaaac cgacttcata accaatctcc gctacggtca
     8761 tgtccgaaga agcaagcaaa gaagctgcct tcttcaaacg ggcgatacgg agcaattcat
     8821 tcggagagta gttagtcaat gatttaatct tgcgataaag ctgcacacgg cttagtccca
     8881 tgtctttgcc caagtcctcc acattcaaac cggagtctcc cattttctct tcaatcaatg
     8941 acttgaatct ttctacaaaa tccttgtcca tatcgcagac atcttctttt gccaatgtct
     9001 gcccgtcacc aaagaactgt ttcagacgac ggtgagaatc gatcagattg cggacacgtg
     9061 ccagcaacag ctgtgaactg aacggctttg aaatataaga atccgcacca ccgtcatatc
     9121 cctgaatacg ctgttcgtcc agtgaacacg ctgtcagcag aataaccgga atatgacagg
     9181 tctgtaactc acttttcagc cggcggcaac attcaatgcc atcaatgccc ggcatcatca
     9241 catcagaaat gatcaggtcc ggaacatact tcatagcctt acggattcct tcggagccgt
     9301 ctgccgcttc aatcaccgta tagtctgtat gcaacagcgt atgaacatac gaacggatat
     9361 cctcattatc atcaataatc aatacggacg atttggaaga gtcatatcct ttttccagtt
     9421 cttcctcttc tgccaataga acatctgttg tacgggaatc cgcagaaaca agggtggtat
     9481 ccggttcggc agcaacagcc tcgcaagact gtacaggcag ttcaacggta aagaccgtgc
     9541 cctgtttctc atcgctctct acagagatca taccaccgtg catttctacg aaggctttta
     9601 ccaatgccag tccgattccc gaaccggtat ggtgcatatc gatcttatag aaacggtcga
     9661 atacattgcg gatatgttcg gcagaaatca tggaaccggt atttgccacc gtgaaacgta
     9721 tccatcgctt gtcctcttta ctaagggaag acagacggat ggctattttc ccgttttccg
     9781 gtgtaaactt aaaggcattg gacaggagat tgaaataaat acgttccagc ttctccatgt
     9841 ctgccagtgt atgataatcc gtatccggca tactatcaaa agaaaaatgg atatgcttct
     9901 tacgggctgc cgcctgaaaa gactcattcc atccttcgaa agaagaaagg acatccaccg
     9961 taaccggagt atattccatc ttgccgtttt catatttacg gaaatccaga atctgattga
    10021 ccagacgcag aaggatgttc acattccgct gaatcagcat gagcatccgg tgctgatctc
    10081 cgctcagtgt cttgtccgcc aacaaatgtt ctaccggatc ggcaaccaat gtcaacggag
    10141 tacggaagtc gtgagaaata ttggtgaaga ataccagctt ggcatgagta gcttcttcca
    10201 gttgatgaga aagttgtatc aattggtcac gctgttcttc cagtttgtca cgttgctctt
    10261 ccaattgttg cttctgctta aaaagttctt tattcaagcg attctttgag cggagtgatt
    10321 tataaacgac caataataag ccggctacca ataaaaggat aatcagactg ccgtataaaa
    10381 cgacctgttg tgtagctacc tgagagagat agccaccgat acgtccgttg agcgtttcaa
    10441 tctttttgtc gagttcggaa atgtgtgtgg tctgcaactg catgacgtgt gcgttggtac
    10501 ggtccacaac agcggtattc atcaccgttt ctttgggata gggtttcttc tccagaatat
    10561 ccatagccag ttgcagtacc ttatcaccat tggtcggata gataaaggtg gcatccagca
    10621 cactgtccag aaccagttcc agtccgtttc ccttacccgg caaggcatct atgccgacaa
    10681 aaatcatttc cttctcccgc cctgccatct ttgctgcctg ataggcaccc ggagcgatac
    10741 ggtcattatg ggcatacaca gcatcaatct taggatgcct ccgaagcata ctatccattt
    10801 ctatctctgc cggaccacgt tcccaagcag catccgcttt atcaatcagc tttatatccg
    10861 ggaatttact gatggcagcc ataaatccct gatgccgttc cattgcagga gtcgaaccgc
    10921 tcaatcctgt cagttctact atatttccct tccctttcag actggaggca atatagtttc
    10981 ctaccgaacg accaatttca taattatcgg ctccgatata ggcagtatat ttatccgaaa
    11041 gaatcttccg gtctacaaga ataacgggga tgcctttctg ataagcttct tctacaatcg
    11101 gagtcatagg agcagcttcg ttagcggaaa taatcagcag atcgactcct tcgtccataa
    11161 aataatggac atcttccgcc tgcttactgt tatcatcccc tgccgaacgg atttccaccg
    11221 aaacaccatt ataaaacatc gcttcccgaa gaatctcatc attcatctta tgtcgccatg
    11281 aatcatcgct gcattgagcc accccaatac gaaaacgggg tgtatcctgc cggcaagccg
    11341 tcatcccgat taaacaaaac agcaccagca tccacttcag atatctcatc gtcttcatcc
    11401 atctcatcat ttcgtagttc tttctgtaat ccaattaaga acaaaaataa gaaataatac
    11461 tgtaaagttc tctaacttca gctatttatt attctaaaaa gaaggaaagc agtcctcttt
    11521 cagaccatcg gaaagtatta acaaaagtat aaagcgtaaa acaaacactt aatcaatgtt
    11581 ataaaacata gcgttttact tggataattt gcagatttca cagaagtccg tatctttgca
    11641 ctgtgttttt catagtatta gatttaaggt taacaaaggt tggagcaagg cgttgctcct
    11701 ttttttatgc cctgaccttt catctaccgg ttagttttca tcccattcct tttccagttt
    11761 accatcaata gtgtagcgtt tccatcgtcc tacacggcga ccattcttat attccccaca
    11821 ttcacgaagc tggtcattct ttacataacg agcttcgaac ggtccgttct gccttccgtt
    11881 cacataggta gaagtttccc aataatcaaa gcggttgctc actatcagcc gtcgttcctt
    11941 gccatgcaat ctgccggcct gataggtagc ttcatatctc aattcaccat tttccagatt
    12001 atattcacgg tataaaccgt ctttacgatc gttcttcata taatattctt tctgccttac
    12061 cccacttccg ttggcaaatg agacatggag tccatcttct tttccatcca gataggtttc
    12121 aatcatcagc gtatctccgc tttcagcaaa agtagtccac cgaccattct tctttccatt
    12181 cttataacta cccagtatac gtggcgagcc aaacgtaaac acggacgaat attcaccgtc
    12241 ctgcaaacct tcttcattga aataaacggt ctcatacaaa tcatatgtac ctttcagaaa
    12301 agtatactgt ttgcctacct gcttcccgtc cttgtaatta tgctctttcc gcaaagtacc
    12361 gtcagattcg tacgacagtt gcttcccgtg ctctttcccc atccggaagt ttctttcact
    12421 ttccactttt ccggtagtaa agtaactttt gctcgtaccg tccagcttac cttccttata
    12481 ggacttttct tctttcagct taccgtcaaa cttggagtta atcttgaaga ggccatcctt
    12541 ccgcccttct ttataacttc cttccgttat taatatattg tccacatatt ctttgtatcc
    12601 gccatcataa aaaccatctt taaaagatgc cagcacatag gcggaatgat aaccatctat
    12661 gatgcgatgt tcgccattca atgctttttc cgttttcagt tcccgaaaca acagtctgcc
    12721 atcgcctaca ttgacaacgg atacctgatc gatcttatat tccttttgcg caaacaaagg
    12781 aagagcaaga tataaaaaca aaaatacgtt ccagcttttt gatctgagga agtttgaaat
    12841 gtgtttcata aagtagtttt ctctttttaa tttattattt aaagacctgc cgcaaagata
    12901 ggcaatcggc ttataaaaca aggaaagaaa gagggggaca attagagaaa agaacatctg
    12961 ttattatcat tctaataatt aacagattaa gtagtaaatc aaaacacagg gaagggggac
    13021 atttactgaa ataagaaaca gaaaagaaga tgtgtcaaaa gcaactaaat tcccctcctt
    13081 caggaaggag gagagtttag ttgcttttga cacatttaca tttgcagtat taaatatcac
    13141 aacaaaatat aagtgtat
//
