LOCUS       c00012_gnlPro..        13776 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KAHCKFMG_12.
ACCESSION   c00012_gnlPro..
VERSION     c00012_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 00:11:34
            Original ID  :: gnl|Prokka|KAHCKFMG_12
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 48384
            Orig. end    :: 62160
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13776
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[58384:61874]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13490
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13776
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13776
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             261..779
                     /locus_tag="ctg12_44"
                     /transl_table=11
                     /translation="MKAFLVPLLYSALLSGASLAFGETAAGTASPAAAAPAEKIPSAES
                     LINQAFSFAINIQQTLAGVQDKESADNAVKTLQDIQKDIRHFLQLQDKLNDAEKEKEDA
                     LIEKMKKRMEMLDNRCRQEGKRLFEARYYGSAALKDILENSDEFSDLVEPDEDGAHPGA
                     LRENEEAGQ"
     CDS             724..1653
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_45"
                     /sec_met_domain="adh_short_C2 (E-value: 4.1e-75, bitscore:
                     244.2, seeds: 358, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTGRTPVHSGKMKRPDSSPPPRFSPLFFHSRHALSPYGFLRGQV
                     HFKLAGTVKNGFTVGSMQKLAGKTAIVTGAGRGIGNAVARRFASEGAKVILISRSPSSC
                     GGAAEEINKEFPDSCKAYPCDVADYAAVQETMAAILKDFPQIDILVNNAGITRDSLMLR
                     MKEEDWDAVLDTNLKSAFNTVKALQRVLMKSPAGRIINMSSVIGLVGNIGQANYAASKA
                     GLIGFTKSLAQEFAPRKVTCNAIAPGFISTEMSNAIPDNLKEEIVKKIPLKEQGSVEDI
                     AALTAFLASDDARYITGQVIACDGGMTM"
     CDS             1677..2882
                     /locus_tag="ctg12_46"
                     /transl_table=11
                     /translation="MRGIFLVSCFLGGSALLAGCREENNSPRPATEDAARITSARQWGE
                     SRSALQKRELDRAAGPALPIPDDLPSRELVGTTRQIHQLIEASGNPARFESYTETVPAA
                     GASLRMIAIPGGTFLMGSPAEEPHRKPDEGPQHKVSISPFWISETEIPWELYTAFMENG
                     RPRAKDGQLLEEQPDDELWDSVTQPTAPYTAMNLGMGHGYEHGLPAISMSHHAASKFCE
                     WLSAQTGHYYRLPTEAEWEYACRAGSPGAYSYGNVEASLDQYAWYWNNSNDRYQKTGSK
                     KPNKWGLRDMHGNVAEWVLDSYVPDAYGKRSGLPAKDPLVIIPGAPHIVRGGSWEDDPD
                     SLRSAVRRASTPAWNRQDPQNPKSIWYLTDGGMIGFRVVRPMNIPDVMTMHRLWNFSKG
                     EP"
     CDS             3016..3318
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_47"
                     /sec_met_domain="Acetyltransf_1 (E-value: 3.6e-09,
                     bitscore: 28.9, seeds: 223, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVSPSFIPEQDAVAVHGSRIVGNIVDATSVIRADDGKEYEVLGM
                     GAIAVLPEYQSRGIGRRMIGYTRNRVREMGFRAIFLYGDPDYSSRCGFVPAETLG"
     CDS             complement(3446..4222)
                     /locus_tag="ctg12_48"
                     /transl_table=11
                     /translation="MTGAQEQKLKCICWDMATNNYEYRRVYLDKVKTDYGEFSSYNQKN
                     NVYKQLINEINRYDKDFRIETIKWLKNIDSEKENELFAQEIRMMVAMIIKEQSKNGRPN
                     EKIKNQIEINIENKFRKKKNIIVAEAIKKKFLTKIKDRMIALMESSILSIGDRSNYLFW
                     KTNIINAKDCASEDNLLAGNLKTRYENDLIRHRHRCAHNLTSYQQNLPTLSALAENEHR
                     YHNYFFRFTTLILIDEIFMLLYNEYIKQIECNISHI"
     CDS             complement(4356..5534)
                     /locus_tag="ctg12_49"
                     /transl_table=11
                     /translation="MKRLIKSLKEKQFVQPVTIALYDVGEQKRNLILDGQQRLTSILLA
                     YVGYLPDRKKFSDGDNEMLAKEDDSASDESDNSYKHNPILWKFSELLANQNSKEDIIKR
                     IHEDGRYAQLTDKEFIDLTDDFFENTFIGFSYIVPESRNPTTVQTVFSKLFRNINYFGR
                     KLDALESRKSLYFQDKNLVNYFEGKTENNSDVLCGIKIMENLQPYKIDFVRYLSILSQY
                     SANCSNERKVLVGYSAFGSRESFYADYVSYILGQGADEQESRPDKFNYFDFREVFPNNC
                     WKQRFLNLKIAIDRLKKIMGLNDRSSFSTWLEADYWLFGLIYHIVFKGSVLKEDLSMEI
                     KKDMSISLKNEIDEKIIDKKKDSSNYMKNINRLGNLRERLKDSCEIYGKYVQ"
     CDS             complement(6067..6174)
                     /locus_tag="ctg12_50"
                     /transl_table=11
                     /translation="MKEWLFVKICGLMVFVILLLTISYIIIHHDTKRIK"
     CDS             complement(6272..6982)
                     /locus_tag="ctg12_51"
                     /transl_table=11
                     /translation="MGSFAVSSEAATVFNYYTPGTDNYNSTIYGFYLGLGSSSLAPSDS
                     SSPSSLSGEIRLDSFTLRGAANNLGANVTYGFLVLNGSDNSVIGWSTNTGTTAAGINLT
                     FSFSSLDGSPLLLDAALTYRFLAVSQSVMDLMQDTSKTYLYAAGGTAAPTANTEGDTVT
                     ISGGLTAPGIRGHYDAEGAPGDSVVITGANGTNTFSLLSPIFTEIRGEMVPEPATVSLG
                     LLGLAALMMRRRRA"
     CDS             complement(6939..7127)
                     /locus_tag="ctg12_52"
                     /transl_table=11
                     /translation="MNYKYNILTLNIFNCLRIPNPIGEFQIRYKLPSKRNNKYEENTDI
                     FNRDGKLCCFLGGSDRF"
     CDS             7307..8014
                     /locus_tag="ctg12_53"
                     /transl_table=11
                     /translation="MNKLLSTLILSAGMSLSATAATSLLDSSIVGYSDFASQTADFGTR
                     KDSVSITSDDSNLTLSGITFNGYGANNRDVMSVTMVLDLSKINTPVAYTALFNAKNSSV
                     SWGVGLNTDRKLQGLWNNTSYSGPVVDTPLGTEGSLTISVVTGDLGTRIYFGDSATYYS
                     NSGLKFGNQQIDQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGL
                     LGLTALMMRRRRA"
     CDS             8269..8676
                     /locus_tag="ctg12_54"
                     /transl_table=11
                     /translation="MQSPASLSIRNSPSFQQSISPHGPDRCGSVRRQQTPSPKQGKGVG
                     KWLSLNLYPPFPSMNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPDE
                     FLFDGIGRLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(8710..9525)
                     /locus_tag="ctg12_55"
                     /transl_table=11
                     /translation="MMAFIEPHIHMVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSAD
                     GFRDYFVQLTECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLG
                     IGEIGLNRNTSHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLD
                     PCRVLVDHCEEHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADW
                     GDSDPLALTALACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(9528..9800)
                     /locus_tag="ctg12_56"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             10001..10702
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_57"
                     /sec_met_domain="SucD_FumR (E-value: 2.4e-13, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             10724..12682
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.1; E-value:
                     4.2e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_58"
                     /sec_met_domain="FAD_binding_2 (E-value: 3.9e-54, bitscore:
                     176.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.1e-37,
                     bitscore: 120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             12723..13490
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.5; E-value: 8.6)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_59"
                     /sec_met_domain="Fer2_3 (E-value: 2.1e-23, bitscore: 74.4,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 7.1e-11, bitscore: 34.5,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4e-06, bitscore: 19.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKTLNLTLKVWRQENREAKGRIETYAAKDIPVDASFLEMLDIVN
                     EGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPERQVTTCQLHMRKFKDGDTVWIE
                     PFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAPNANNIAVEKVKADAAFDAAAC
                     IGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSKRVLAMMKQMEAEGFGNCTNQY
                     ECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
ORIGIN
        1 ccctggtgca ggctctgaag cattatgaag gaacactggt cttcatctcc cacgatgtgc
       61 acttcatccg ttccctggca caaaaaaccc tgcatgtgaa ccgggggacc atcaccgcct
      121 acgcaggcgg atatgactac tatctggaaa agtcaggcat tctggacgat gaaaaaggcg
      181 gcatcacggc ggaataaggc tcttttttca gtttcccctt tttccttgcc gtggatttca
      241 tcctgcctta aaagaacagg atgaaggctt ttcttgttcc tctcttatat tctgcgcttc
      301 tgtccggagc ctctcttgca tttggtgaaa cggccgccgg aacggcttcc cccgcagcag
      361 cggctccggc ggaaaaaatt ccttccgcgg aatccctgat caaccaggcc ttttcctttg
      421 ccatcaatat ccagcagacg ttggcaggcg ttcaggacaa ggaaagcgcg gacaacgccg
      481 tcaaaacgct gcaggacatt cagaaggaca tccggcattt cctccagctt caggataaat
      541 tgaacgatgc ggaaaaggag aaagaagacg ccttgataga aaaaatgaaa aaacgaatgg
      601 aaatgctgga caaccgctgc aggcaggaag gcaaacgcct gtttgaggcc cgctattacg
      661 gttccgccgc cttaaaggac attttggaaa attcggatga attcagcgac ctggtagaac
      721 cggatgaaga cggggcgcac cccggtgcac tccgggaaaa tgaagaggcc ggacagtagc
      781 cccccgcccc gtttctcccc cctctttttt cattcccggc acgccctttc cccgtatggg
      841 ttcctgcgcg gccaagtcca tttcaagctt gccggaaccg tgaaaaacgg gtttactgtg
      901 ggcagcatgc aaaagttagc aggtaaaaca gccatcgtta ccggcgcggg ccgcggaatc
      961 ggcaatgccg tcgcgcgccg cttcgcttcg gaaggagcca aggtcatcct gatcagccgc
     1021 agtccatcca gctgcggggg ggccgcagaa gaaatcaaca aggaatttcc ggattcctgc
     1081 aaggcctacc cctgcgacgt agcggattac gcggccgttc aggaaaccat ggccgccatt
     1141 ttgaaagact tcccgcagat tgacatcctg gtgaacaacg ccggcatcac gcgggactcc
     1201 ctgatgctcc gcatgaaaga ggaagactgg gatgccgttc tggacaccaa cctgaaaagc
     1261 gcgttcaata cggtcaaggc cctccagcgc gttctcatga aatccccggc cgggcgcatc
     1321 atcaacatga gctccgtcat cggtctcgtc ggcaacatcg gccaggccaa ttacgccgct
     1381 tccaaggcgg gcctcatcgg tttcaccaaa tcactggctc aggaattcgc tccgcgcaaa
     1441 gtcacgtgca acgccattgc tcccggcttc atctccacgg aaatgtccaa tgccattccc
     1501 gacaatctca aggaagaaat cgttaagaaa atacctttga aagaacaagg ttccgtggaa
     1561 gatatcgccg ccctgacggc cttccttgcc tctgacgatg cccgttacat caccgggcag
     1621 gtcattgcct gcgacggagg catgacgatg tagggcattc cggttttctc cattccatgc
     1681 gcggcatttt ccttgtttcc tgctttctgg gaggaagcgc cctgctggcc gggtgccggg
     1741 aagaaaataa ttccccccgc ccggccacgg aagatgccgc gcgcattacc agcgcacgcc
     1801 aatggggaga aagccgatcc gcgctgcaaa aacgggaact ggaccgcgct gccggtcctg
     1861 cccttcctat tccggatgac ctgccgtccc gggagctggt cggcacgacg cgccaaatcc
     1921 atcagctcat tgaagcttcc ggaaatccgg cacgttttga atcctacacg gaaacggttc
     1981 ccgcggcggg agcttccctg cgcatgatcg ccataccggg aggaacgttc ctcatgggga
     2041 gtcccgcgga agagccgcac cggaaaccgg acgaaggacc gcagcataaa gtgagcatct
     2101 ctcccttctg gatctcggaa acggaaatcc cctgggaact ttatacggcc ttcatggaaa
     2161 acgggcgtcc gcgcgccaag gacggccagc ttctggagga acagccggat gacgaactgt
     2221 gggactccgt tacgcagcct accgccccct acaccgccat gaacctgggc atgggccacg
     2281 gctatgaaca cggtctgccc gccatctcca tgtcccacca cgccgccagc aaattctgcg
     2341 aatggctgag cgcccagacc gggcattact accgcctgcc cacggaggcg gaatgggaat
     2401 acgcctgccg ggccggctcc cccggcgcct attcttacgg aaacgtggaa gcctctctgg
     2461 accagtacgc ctggtactgg aacaactcca atgaccgcta ccagaaaaca ggctctaaaa
     2521 aaccaaataa gtggggactc cgggacatgc acggaaatgt ggcggaatgg gttttggact
     2581 cttacgttcc ggatgcctac ggcaaacgga gcggcttgcc cgcgaaagac cctctggtca
     2641 tcatccccgg cgcccctcac atcgttcgcg gcggttcgtg ggaagacgac ccggacagcc
     2701 tgagaagcgc tgtgcgccgc gccagcaccc ccgcctggaa ccgtcaggat cctcaaaacc
     2761 ctaaaagcat ctggtacctg acggacggag gcatgatcgg gttccgcgtg gtgcgcccca
     2821 tgaacattcc ggacgttatg acaatgcacc gcctctggaa tttctccaag ggggaaccgt
     2881 aaagaacaac ccttcatgac cattgcatta agaacggaac aatccgcaga ccatgccaaa
     2941 acggaacatg tcacgagaga agcgttctga aactatttcg tccccggctg caatgaacat
     3001 tacctgctcc atatcatgcg cgtcagtcct tccttcatcc cggagcagga tgcagtcgcc
     3061 gtccacggca gccgcatcgt cgggaacatc gttgatgcaa cgtccgtcat cagggcagac
     3121 gatggaaaag aatatgaagt gctgggcatg ggggccattg ccgttcttcc ggaataccag
     3181 agccggggaa taggacggcg gatgatcggc tacaccagga accgggtgcg tgaaatgggc
     3241 ttccgtgcca ttttcctgta cggcgacccg gactactctt cacgctgcgg attcgttccc
     3301 gcggaaacgc tgggataata tgtatgcagc ggtctcgcat ttgttgcatt aacaaatgtg
     3361 taatgaaata ttattaatat aacaacatta atatatattt cataacaacg tgcattctac
     3421 aatcaagata caaaaataaa aataattata tatgcgatat attacattct atttgtttta
     3481 tatactcatt atataagagc ataaatattt catctatgag tatcaatgta gtgaaacgga
     3541 aaaaatagtt gtgataacgg tgctcgtttt ctgccaaagc actcaatgtt ggaagatttt
     3601 gctggtaaga agttaaatta tgtgcacatc tatgacgatg tctgataagg tcattctcat
     3661 atcttgtttt taaattccca gcaagcaaat tgtcttctga agcacaatct tttgcattaa
     3721 ttatatttgt tttccaaaac aaatagttgc tcctatctcc aatagacaat atggaagatt
     3781 ccataagtgc tatcattcta tcttttattt ttgtcaaaaa cttcttcttt atagcttctg
     3841 ctacaattat gtttttcttt tttctaaatt tattttcaat atttatttca atttgatttt
     3901 tgattttctc attcggcctc ccattttttg attgctcttt tattatcatt gcaaccatca
     3961 tcctaatctc ttgagcaaaa agttcattct ctttttcaga atcaatattt tttaaccatt
     4021 ttatggtctc tattctaaaa tctttatcgt acctattaat ttcatttatc aattgcttat
     4081 agacattatt tttttgatta taagaagaaa attctccata atcagtttta actttatcaa
     4141 gatacacacg ccgatactcg taattatttg ttgccatatc ccaacaaata catttcaatt
     4201 tttgttcctg agctccagtc atttttagaa aaagagattg tactacataa tcgcaaagcg
     4261 gataagtttc catattacac cctacaggta aacaagcatt aacgccgtct ttaaggatat
     4321 aaaaaatagg agtctttata aatttcgaat gaatactatt gtacatactt tccatatatt
     4381 tcacatgaat cctttagtcg ttctcttaaa ttcccaagac gatttatatt tttcatataa
     4441 ttactactat cttttttctt atcgataatt ttttcgtcta tttcattttt aagagaaatg
     4501 ctcatatcct tttttatttc catagataag tcttccttta gcacactacc tttaaataca
     4561 atatgatata ttaatccgaa aagccaataa tcagcctcca gccatgtact aaatgaactt
     4621 cgatcgttta atcccataat tttttttaat cgatcgatag caattttaag attgagaaaa
     4681 cgttgtttcc aacaattatt aggaaaaact tctctaaaat caaaataatt aaatttgtcc
     4741 ggcctactct cttgttcgtc tgctccctga cctaatatgt aagaaacata gtcagcgtaa
     4801 aaactctcac gtgatccaaa cgcggaatat cccacaagaa cctttctttc attactgcaa
     4861 tttgccgagt attgcgaaag aattgataaa taacgaacaa agtcgatttt gtatggctgc
     4921 aagttttcca taatctttat tccacataat acatcgctat tgttttccgt tttcccttca
     4981 aaataattta ctaaattctt atcttgaaaa tataatgatt tacgactttc taatgcatca
     5041 agcttccttc caaaatagtt tatatttctg aacaactttg aaaaaacggt ttgtactgtt
     5101 gttggatttc tactttctgg aacaatatac gaaaaaccaa taaaagtatt ttcgaaaaaa
     5161 tcatccgtaa ggtctataaa ttctttatct gttaattgtg cataccttcc gtcttcatgt
     5221 attcgcttga tgatatcttc tttgctattc tgattagcta ataattcact gaatttccaa
     5281 agaataggat tatgtttata agaattatcc gattcatcag aagcactatc gtcttcttta
     5341 gctaacattt cattatcacc atctgaaaat ttttttctgt ccggtaaata ccctacatac
     5401 gcaagaagta tagatgtaag tcgttgttgt ccatccagaa ttaagttgcg tttttgctcg
     5461 ccgacatcat aaagagctat tgttacaggt tgtacaaatt gcttctcttt aagtgatttt
     5521 ataagccgtt tcatatctcg ttcttgccaa acgaaatgcc tttgataatc aggaagttca
     5581 atatttcttg taagcattaa atcaatccaa tgtttcaagg aatattctcc gtagtatact
     5641 ctatcatcta atgattccat ataaaaaata tttaatggta ataattttat gggcaaattt
     5701 actattattc tgtaagtcga actaaatttc aattatcaaa ttcagcgaat tatgggttac
     5761 agttactgaa atttatattt taattcatac tcttcaagtt ttctgtataa cgttattctt
     5821 cttattccga gcagtttgga agaaacacta cgatttccag ctggtccgtg ttaaggcacg
     5881 taaaattgtt ccttatcctt cgcattattg cacatgacga aattgacggg cgaagccggt
     5941 ttaatcaatg gtgtatacaa cctgcaggta tgatatatac tgcctttttc agaaaactat
     6001 cagtgtcttg ttctatgtca taaactgttt cagttgttcg attaaatccg tagttttgca
     6061 cttgtactat ttgatacgtt tggtgtcatg atgtatgata atataggaaa tagtcaacag
     6121 taaaataaca aataccatca gaccacatat tttcacaaaa agccactcct tcatagcaac
     6181 tatttttccc ctatataatc tttgaaaata aaaaacaagg gctgttcttg cgaaacagcc
     6241 ctcatccgcc gatttttcgc catcaggaag ctcaagccct gcggcggcgc atcatcagcg
     6301 cggccagtcc cagcaggccc agggaaaccg tggctggttc cggcaccatt tcccctcgga
     6361 tttccgtgaa aatcggggat aataagctga aagtattggt tccgttggct cccgtaataa
     6421 cgacagaatc accaggcgct ccctcggcgt cataatggcc gcggatgccg ggagcagtca
     6481 atccgccgct gatcgttacg gtatctcctt ccgtgttagc agtaggggcg gctgttcccc
     6541 ccgcagcata taaatacgtt ttagacgtat cctgcatcaa gtccatcacg gactggctca
     6601 cggccaggaa acggtatgtc aatgccgcat caagaagcag gggagaacca tccagggaag
     6661 aaaaactgaa cgtcagatta atccctgctg cagtagttcc cgtattggtg ctccagccga
     6721 tgaccgaatt gtcggagcca ttcagcacca ggaagccgta agtgacatta gcgcccaaat
     6781 tgttggcggc tccgcgcagc gtaaaactgt ccagtctgat ctctccggac agggaggagg
     6841 gagaagagga atcggaagga gccagggaag aagaccccag gccaagataa aacccataga
     6901 tggtactatt gtaattatcc gtaccgggag tgtaataatt aaaaacggtc gctgcctccg
     6961 aggaaacagc aaagcttccc atcgcgatta aaaatgtcag tgttttcttc atatttatta
     7021 ttccttttgg atggcaactt gtagcgaatt tggaattccc caatcggatt tggaatccgc
     7081 aagcaattaa aaatattaag agttagtata ttgtatttat aattcattga aaataatgat
     7141 tttttaatat ctctggtcct tttgctaaga tgacgggtca gtctttgtta ttcattggtt
     7201 tcatgattga tttggcctct ttttcattac ttgacggatt ccaaattcgt tattcaagca
     7261 caagtacata cattgaacct tgcatcattt tattaagata ctgaccatga ataaattatt
     7321 atccaccctg attctttcgg ccggcatgag cctaagcgct accgcggcta cctctctgct
     7381 ggatagctcc atcgtgggat attcggactt tgcctcccaa acggcggatt tcggcacccg
     7441 gaaagattcc gtttccatca cgtctgacga cagcaatctg acgttatccg ggataacctt
     7501 caacggatac ggtgccaaca accgcgacgt tatgtctgtg acgatggttc ttgacctgtc
     7561 caaaatcaac actccggtcg cctataccgc tctgtttaac gccaaaaaca gcagtgtaag
     7621 ctggggcgtg ggcctgaaca cggaccggaa actccaggga ttatggaaca acacctcata
     7681 cagcgggccc gtcgttgaca ccccgctggg cacggaaggt tccctgacca tttccgtagt
     7741 caccggagat cttggcaccc gcatctattt tggagacagc gctacgtact attccaacag
     7801 cggcctgaaa ttcggcaacc agcaaattga tcagattctc atggacgcag gactggctga
     7861 atccatcgaa cagctctaca ttcacgactc cctcctttcc caggaacaag ttggtcaact
     7921 gatgagtgaa atcgccagca ttccggaacc cgccacggct tccctgggcc tgctgggact
     7981 gaccgcgctg atgatgcgcc gccgcagggc ataagcctgt accgtccgcc tccctatatt
     8041 caaaggccgg ctcacaaaat cgtgagccgg ccttttcctt atccgttcaa acatctgccg
     8101 aaaaaacaga ggggaaaagc ttccatttgc tgcggcaacc tcacggccag cacttgacgg
     8161 aaaaatggca ttcagtctcc cccggtaggg tcatttcaag agcttccggc cccgccccac
     8221 ttccgtacac gccccttttt cccatgccgg gacagccgga accggagcat gcaaagcccg
     8281 gcttccctca gcatccggaa cagcccatcc tttcagcaat ccatttcccc gcacggtccg
     8341 gatcgctgcg gttccgtccg tcggcaacag actccttccc cgaaacaggg aaaaggagtg
     8401 ggaaaatggc tgagcttgaa cctttatccc ccgttcccgt ccatgaacct tcaaaaacag
     8461 cagctgctac tgcgcctgtt ccggtatttc aaaagcagaa aaggagaacc gcgttttttc
     8521 aacaaacgga atatatgcct tctggccgcc gccggcgcct acatcctgac tcccgacgaa
     8581 ttcctgtttg acggaatcgg caggctgggc cttctggatg acgcggcggt catcctgggc
     8641 gccgtcctca ccgtcttttt cccggacggg gactagaggg ccgtaccctc cgccgcgcct
     8701 cgggcggaat tagcgggacg acactttccg gaacttcggg gactgtccca tgaatgtctc
     8761 cggattttcc aggagaagac gttccgtttc ctgccgggaa aaaccgcgcc tgcgtagctc
     8821 gcaggccagg gccgtcagcg ccaggggatc ggaatccccc cagtccgccg cggaattggc
     8881 ccagacacgg tccattccgt acaattccag aatatccgcc gcccgcttgg gattcagctt
     8941 actggtggga taaagggtca gcccggccca gtaaccggcc tccttcacca gcgggaaggt
     9001 atgttcctca cagtgatcca ccagcacgcg gcaagggtcc agatccggac ggtttttcag
     9061 ggcggaaaga atcattacgg tccccttaag cttgtcttcc agatggggag tgtgaatcag
     9121 cacaagctgg ttgaggcgca ccgccagatc cagatgctct tcaaaaatag tcatttcatg
     9181 ggaagtattc cggttcagcc ctatttcccc gatgccgagg acattgggcc ggtcaatgaa
     9241 ctccggaatc agtttcatca catcccgcgc gaaagccacg tcctgcgcct ccttgggatt
     9301 gatgcacagc catgtgtaat ggtccatgcc gaacttggcc gccctggcgg gttcgcattc
     9361 cgtaagctgt acgaaataat cccggaaacc gtccgcggac gaacggtcgt aaccggccca
     9421 gaacgccggt tcccctaccg ccaggcagcc ggcctgcgcc atggcccggt attcgtccgt
     9481 ggtgcggcac accatatgta tatgaggttc tatgaaagcc atcattctta tttgctgagg
     9541 ttcggggctc cgcaggccgc tttggctgcg gcggtttccg gcacggtgtc atccctgtag
     9601 gaaagggctt ccagaatggc ccggacgcgt ccggggccgg atgcggacaa gaggggaaga
     9661 acatccatca gggcatggta gcggaaatcc gcctcccctt ccccgcggtc cacccggtcc
     9721 agaaatgcgg ccacatccag aacgccggcg cgcgccgctg cgaaatccgc gtccagcacc
     9781 tcctttttac ttcttttcat gcacagacga tacgcctatg cggaaagcct cgtcaagccg
     9841 gaacaggcaa caaaatgata accattccaa acttataaac agcaacctct ttccccggtt
     9901 tttcaaaaat ccgaaaagcg ccggaaattc aagaagaggc ttgccatccg ggcttgaacc
     9961 gggcatcctg tgaagacgca tttatttcat tagagcgcct atgaatgcac tagtaaaaac
    10021 catatgtaca ttcgtgacat cctccatcgg ccgcaaaatc attgtggctc tgacggggtt
    10081 atgtttggtc ttgttccttg cgggacacct ggcaggcaac cttctcatct tcggaggccc
    10141 tgaatggatc aacacctacg cccacggcct gcactccatg ccggaagcag ccctctgggg
    10201 aatccgcgcg gggcttgcgg tgatcttcat catccacgtc tggctgacca tccagctgaa
    10261 gctggaaaac catgcggccc gcgaacccta cgtgttcaag aacaccatta aggcaacgct
    10321 ctcctcccgc tacatgatct ataccggttt gaccgtcctg gtgttcctga tctaccacct
    10381 gtaccagtac accctgcgcg tgggatacga ccccgcccag ttcaccacct ttatttccga
    10441 cggtacggtg gaaacctttg acgtgtacaa gatgatcgtg accggattct ccaacgtatg
    10501 gtgctccgcc ttctacatcc tggccgttct gatgctgttc agccatctgc gccacggggt
    10561 acagtccatc ttccagactg tgggcgtcga ttcccgcaaa atccggccct tctacaactt
    10621 tatcgccatc gcctacggcg cgattatctg cctgggcttc atctccgtgc cggtctcggt
    10681 tcttctgggt atcatcaaat aaccatcaac tcctctcaaa gtcatgatta attttcccgt
    10741 aagcgactgg atgccggatg ccaaaattcc ctccggccct attcaggaca aatggtccaa
    10801 gtacaaactt gagtccaaac tgatcaatcc gaacaacaag cgcaagtaca cggtacttgt
    10861 ggtaggttcc ggcctggctg gcgcctccgc tgccgccacg cttgccgaac ttggctacaa
    10921 cgtcaaatgc ttctgctacc aggacagccc ccgccgcgcc cactccattg cggcccaggg
    10981 cggcattaac gcggccaaga actaccagaa cgacggcgac tccgtttacc gcctgtttta
    11041 cgacaccgtt aaaggcggcg acttccgcgc ccgtgaagcc aatgtctacc gtctggcgga
    11101 agtctcctcc aacatcattg accagtgtgt ggcccagggc gttcccttcg gccgtgaata
    11161 cggcggcctg ctggacaacc gctccttcgg tggcgcccag ctcaagcgaa ccttctacgc
    11221 acgcggacag acgggccagc agctcctgct gggtgcctac caggccctgg aaaaggaagt
    11281 ggccaaggga cacattgaaa tgttctcccg ccatgaaatg atggatctgg tgttggtgga
    11341 cggcgaagcc aagggcatcg tcacccgcaa tctggttacc ggcgaaatca aatcctacgc
    11401 aggggatacc gtcctgctct gcacgggcgg ctacggcaac gtgttcttcc tgtccaccaa
    11461 cgcgatgggc tgcaacgtca ctgccgccta caaggcctac aagcgcggtg ccttcttcgc
    11521 caacccctgc ttcacacaaa tccaccccac ctgcattccg gtcaagggcg actaccagtc
    11581 caaactgacg ctgatgtcgg aatccctccg caacagcggc cgcatctggg tgcccaagtc
    11641 ccgtgaaacc gcagaaaaaa tccgtaaaaa ggaaatcaag ccttccgatg ttcccgaaga
    11701 agaacgggac tactacctgg aacgcaagta tccctccttc ggcaacctgg ccccgcgcga
    11761 catttcctcc cgcgccgcca aggaagcctg cgacgacggc cgcggcgtgg ccgtcaccgg
    11821 caagggcgtc ttcctggatt ttgcggatga aatcaagcgc atgggccgcg aatggattga
    11881 cggccaatac ggtaatctgt ttgacatgta cgaagaaatc acggacgacg acccccatga
    11941 aacgcccatg atgatctacc ccgcctccca ctacaccatg ggcggcctgt gggtggacta
    12001 caacctcatg tccaatgtga aggggctgca cgtcctcggt gaagccaact tctccgacca
    12061 cggcgccaac cgcctgggag cctccgccct gatgcagggc ctgtctgacg gctacttcgt
    12121 cattcccgcc acgctgcccg cttacctgac gaccaccaaa cccggcgccg tcaccaccgc
    12181 cgccccggaa ttcaaggctg cggaagacga agtgaaggaa cgcatcaaca agctcctgaa
    12241 tgtgaagggc accaagacgg tggactcctt ccaccgggaa ctgggcctca ttatgtggga
    12301 agactgcggc atggcccgca cggaagaaag cctgacccac gccattgaac gcattcccca
    12361 gctccgcaag gaattctggg aaaacgtgcg cgtaaccggc acggcggacg gcatcaacgc
    12421 ggaactggaa aaagcctgcc gcgtggccga cttcctggaa ttcgcccagc tgctctgcta
    12481 tgacgccctg aaccgccagg aatcctgcgg cgcccacttc cgcgtggaat accagctgcc
    12541 ggacggcgaa gctaagcgca acgacgatga atacgcctat gtagccgcct gggaatacac
    12601 tggcgtggac agcctgcctg ttctccacaa ggaaccgctg accttcgaga acgtgcacct
    12661 tgccatccgc agctacaagt aaagatagcc aatacattaa cactcaaaag aaagattata
    12721 acatggctaa aacactcaat ctcactctca aggtctggcg ccaggaaaac cgggaagcca
    12781 agggccgcat tgagacctat gccgccaagg acattccggt ggacgcctcc ttcctggaaa
    12841 tgctggacat cgtcaatgaa ggcctggtca aggaaggcaa ggaacccatc cattttgacc
    12901 acgactgccg ggaaggcatc tgcggcatgt gctccctaac catcaacggc attccccacg
    12961 ggccggaacg ccaggtgacc acttgccagc ttcacatgcg caagttcaag gacggcgata
    13021 ccgtctggat tgaacccttc cgcgcgaagg ctttcccaat cctgcgggac ctgatggtgg
    13081 accgctccgc cctggaccgc atcatcgccg ccggaggcta tattgacgtg cgtaccggtt
    13141 ccgcgccgaa cgccaacaac atcgccgtgg aaaaagtgaa ggcggacgcc gcctttgacg
    13201 cggccgcctg catcggctgt ggcgcctgcg tggcctcctg taaaaacgcc tccgccatgc
    13261 tgttcacctc cgccaagatc gcccatctca atctgctgcc gcagggccag ccggaacgtt
    13321 ccaagcgcgt cctggccatg atgaagcaga tggaagcgga aggcttcggc aactgcacga
    13381 accagtatga atgtgaagcc gcctgcccga aaggcatcag cgtggacaac atcgcccgcc
    13441 tcaaccgcga cttcatgcgg gccaacgcca aggaaggcct ctgtttctaa agaagattcc
    13501 ttcttaagac gctctgtaaa aactcccggc ggcatcggct gtcgggagtt tttttcatta
    13561 ccaggtttcc ttgaagcagg aataaaatac cagacagttg cttcctcatc gtcgcgcagc
    13621 gtaaaaaatt gttacaccgg aaggcaccca gtaatccagg agaccgtact tggaaatgcc
    13681 ggacgaaacc taagcaggcc ccgtccgaca gcgacggccc catctttctc cgagaaagaa
    13741 aaatattgat tacaggaatt agactgatgc ccggaa
//
