LOCUS       c00159_gnlPro..         3723 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GEGFMLIK_159.
ACCESSION   c00159_gnlPro..
VERSION     c00159_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 21:01:36
            Original ID  :: gnl|Prokka|GEGFMLIK_159
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3723
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3723
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[392:3620]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      393..3620
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..3723
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..3723
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(2..61)
                     /locus_tag="ctg159_1"
                     /transl_table=11
                     /translation="MSTQTTLTPVSAITDIQICA"
     CDS             393..2015
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg159_2"
                     /sec_met_domain="TPP_enzyme_C (E-value: 8.7e-44, bitscore:
                     137.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISGAEIMVKCLEAEGVDIVFGYPGAAICPFYDKVYDSSITHILV
                     RQEQNAAHAASGYARCSNRPGVCVATSGPGATNLITGIATAYTDSIPIVAITGQVRSDL
                     LGRDVFQEADITGACEPFVKHSYLVSKTEDLPRVFKEAFHIASTGRPGPVLIDIPVDIQ
                     ENEIESFEYPESVNIIGYKPNTKGHAIQVKKAVEAINASKRPVIVSGGGVLSSGIKLKL
                     QKFAETTGIPVISTMMGIGVMPSEHELYLGMLGTHGKAVANRALHEADLVIVCGARLGD
                     RAVAAPDQMSENTKVIHIDIDPAEIGKNVKTEIPIVGDMKNVINMLLDSIGDYKVTTMW
                     SETVKNWKKDLYREPPVFDGFVEPRTLVGHLSAMFRSKAILVADVGQNQIWCANNFRIR
                     EGRFLTTGGMGTMGYSIPAAIGAKFARPDRDVIVICGDGSFQMGLNELATIAGNQLGIK
                     IIIMKNARLGMVRELQDKHYGGRHSATILNGDPDFLKIADAYGIDHAEAHSNKEAENII
                     KGIVDSEKPFILVCDVHPDTPSI"
     CDS             2028..2519
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg159_3"
                     /sec_met_domain="ALS_ss_C (E-value: 5.4e-31, bitscore:
                     94.9, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQYTLSILVENQAGVLSKISGLFSRRGFNIDSLAVGVTQDPSVSR
                     ITIVANGDEYIVEQLEKQLNKLIPVIKVKRLNEGEFISRELVLIKVHCAASKRAEIVKT
                     VEIMQAKIVDVSPSSVTVEYCECASRINTLVDLLKPYGIREIVRTGTVAIDRGTASVSV
                     "
     CDS             2580..3620
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg159_4"
                     /sec_met_domain="IlvN (E-value: 1.4e-84, bitscore: 269.8,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1.7e-61, bitscore: 194.9,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDYTKNMTAPIYYQSDCNLDLLKGKKIAIIGYGSQGHAHALNLR
                     DSGCDVIVGLYKGSKSWAKAEAQGFKVYTSAEAAKQADIIMILINDEKQAALYKNDIEP
                     NLEAGNMLMFAHGFNIHFGCIKPPKDVDVTMVAPKGPGHTVRSEYQVGKGVPCLVAVEQ
                     DATGQAKDLALAYALGIGGARAGVLETTFRTETETDLFGEQAVLCGGVCALMQAGFETL
                     CDAGYDPRNAYFECIHEMKLIVDLIYQSGFAGMRYSISNTAEYGDYITGPKIITEDTKK
                     AMRKVLSDIQDGTFAKDFLLDMSDAGSQVHFKAMRKIAAEAPAEVFGKEVRKLYSWSDE
                     DKLINN"
ORIGIN
        1 ttgcacaaat ctggatgtcc gttatcgccg acacaggcgt cagcgtagtc tgcgtactca
       61 ttgccgcaag actcctcaaa aagaaatatt gatttcctca acaatcatta ctgttcccga
      121 gcaggtaaaa ctgttcggga attttcttgt tattactctt atacagatac ttttttggtc
      181 agcattttgc ttttgttgtt aatcatttat tatatctttt tcaggcgatg acagaataat
      241 ttaaaatcct gcaaaaaatt taatttatgg gcaatactgc tctttacttt ttaaggtatt
      301 tattgtataa ttagcggtaa agtaaaaagg tatatttaat gttacaaaac accttttgct
      361 cacaataaaa aggataggag ggacaaaaca taatgatcag cggtgctgaa attatggtaa
      421 aatgtttgga agccgagggc gttgacatag tctttggtta tcccggtgcg gctatctgcc
      481 cattttacga taaagtttac gactcgagca ttacccacat tcttgttcgt caggaacaga
      541 acgctgctca tgcggcaagc ggctatgcaa gatgcagtaa tcgtcccggt gtttgcgtgg
      601 caacttccgg tcccggtgca accaacctca tcacaggcat tgcaaccgcc tatacggact
      661 ctattccgat tgttgccatt acaggtcagg ttcgttccga ccttctcggc agagatgtct
      721 ttcaggaagc tgacatcacg ggagcttgtg aaccgtttgt aaagcacagt tatctcgtca
      781 gcaaaacaga agaccttccg agagttttca aagaggcttt ccatattgcc tcaaccggca
      841 gacccggtcc tgtacttatc gacattcccg ttgatattca ggaaaatgaa attgaaagtt
      901 ttgaatatcc cgaaagcgta aacattatcg gttacaagcc gaacactaag ggacacgcaa
      961 ttcaggttaa aaaggctgtt gaggccatca acgcaagcaa gcgtcctgtt atcgtatcag
     1021 gcggcggcgt gctgagttcg ggtatcaagc ttaaacttca aaaatttgca gaaactacgg
     1081 gtatccccgt tatttcaact atgatgggca tcggtgttat gcccagcgag catgagcttt
     1141 atctcggaat gctcggcact cacggcaagg ctgttgccaa ccgtgctctt cacgaagccg
     1201 accttgtaat cgtatgcggt gcaagactcg gtgacagagc tgttgcggct cccgaccaga
     1261 tgagtgaaaa cacaaaggta attcacattg acattgaccc tgctgaaatc ggtaagaatg
     1321 ttaaaacaga aattccgatt gtaggcgata tgaaaaatgt catcaatatg ctgcttgaca
     1381 gcatcggcga ttacaaggtt acaacaatgt ggagcgaaac cgtaaagaac tggaaaaaag
     1441 acctttaccg tgagcctccc gtttttgacg gctttgttga gccgagaaca cttgtcggtc
     1501 atctcagtgc aatgttccgc tcaaaggcaa ttcttgttgc cgatgtagga caaaatcaaa
     1561 tctggtgtgc aaacaacttc cgtattcgtg agggcagatt cctcacaaca ggcggtatgg
     1621 gtacaatggg ttactcaatt cccgctgcaa tcggtgcaaa gtttgcaaga cccgaccgtg
     1681 atgttattgt aatctgcggt gacggcagtt ttcagatggg gcttaatgag cttgcgacta
     1741 ttgcaggcaa tcagctcgga attaaaatca tcattatgaa aaacgcacga ctcggaatgg
     1801 ttcgtgaact tcaggacaaa cactacggcg gcagacactc cgcaacaatt ctcaacggtg
     1861 atcccgactt cttgaagatt gccgatgctt acggcattga ccatgcagag gctcattcaa
     1921 acaaggaagc cgaaaacatc atcaagggta ttgttgattc ggaaaaaccg ttcattcttg
     1981 tttgcgatgt tcaccccgac actccgtcaa tttaatgagg tgataaaatg cagtatacat
     2041 tatcaatact tgttgaaaat caggcgggcg ttctttcaaa aatttcggga cttttctctc
     2101 gccgaggttt taacatcgac tcactcgcag taggtgttac tcaggacccg tcggtttccc
     2161 gaatcacaat cgttgcaaac ggtgacgagt acattgttga acagcttgaa aaacagctca
     2221 acaagctcat tcccgtcatc aaggtaaaaa ggcttaacga gggcgaattt atcagccgtg
     2281 agcttgtttt aatcaaggtt cactgcgccg cctcaaaaag agccgaaatt gtcaaaacgg
     2341 ttgaaattat gcaggcgaaa atcgttgatg tatccccttc gtcagttacc gttgagtact
     2401 gcgaatgtgc aagccgcatc aacacgcttg ttgacttact caagccttat ggtatccgtg
     2461 agattgtaag aacaggtact gttgccattg acagaggcac agcttcggtt tccgtttaat
     2521 cttacagtta gcatatattt taatttatat gccgcgtttg cggtaaggag gactttaata
     2581 tgaaagacta cacaaaaaac atgacagcac caatctacta tcagtcagat tgcaaccttg
     2641 accttctcaa gggtaagaaa attgctatta tcggttacgg cagccagggt catgcacacg
     2701 ctctcaacct cagggattca ggttgcgatg taatcgtcgg tctttacaaa ggcagcaaga
     2761 gctgggcaaa ggctgaggca cagggcttta aggtatatac atcggcagag gctgcaaagc
     2821 aggctgacat catcatgatt cttatcaacg atgaaaagca ggcagctctt tacaagaacg
     2881 acatcgagcc aaacctcgaa gcaggcaata tgcttatgtt cgctcacggc tttaacattc
     2941 acttcggttg catcaagcct ccaaaggatg ttgatgttac aatggtagct cctaagggac
     3001 cgggtcacac agttcgttca gagtatcagg ttggtaaggg tgtaccttgc ctcgttgctg
     3061 ttgagcagga tgctacaggt caggctaagg atctcgcact tgcatatgca ctcggtatcg
     3121 gcggtgcaag agccggcgtt cttgaaacaa cattcagaac agaaacagaa acagacctct
     3181 tcggtgagca ggctgttctt tgcggcggtg tttgcgcact tatgcaggca ggttttgaaa
     3241 cactttgcga tgccggttac gacccaagaa atgcttactt tgagtgtatc catgagatga
     3301 agctcatcgt tgaccttatc tatcagtcag gttttgcagg catgagatat tcaatctcta
     3361 acacagctga gtacggtgac tacatcacag gtccaaagat catcacagag gatactaaga
     3421 aggctatgag aaaggttctt tctgacattc aggacggtac atttgctaag gacttcctcc
     3481 ttgacatgag cgatgccggt tcacaggttc acttcaaggc tatgagaaag atcgctgccg
     3541 aagctcctgc cgaagtattc ggtaaggaag ttagaaagct ctacagctgg tctgacgaag
     3601 ataagctcat caacaactaa tgcgagtacc tcgctcgtag ttcgtgaagt tagtttgata
     3661 tattcaaatt tctgtcaccc gagcattaca tagtacgaat ttagggtagc ttgattttca
     3721 agc
//
