LOCUS       gnlProkkaHMNNPHKN_101   6862 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HMNNPHKN_101.
ACCESSION   gnlProkkaHMNNPHKN_101
VERSION     gnlProkkaHMNNPHKN_101
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 15:11:39
            Original ID  :: gnl|Prokka|HMNNPHKN_101
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6862
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..804
                     /NRPS_PKS="Domain: PKS_KR (35-160). E-value: 2.5e-08.
                     Score: 25.9. Matches aSDomain:
                     nrpspksdomains_ctg101_1_PKS_KR.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     121.9; E-value: 5.3e-37)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg101_1"
                     /transl_table=11
                     /translation="MVFDSLAACIFGPRQGAGNLSFFFHLPGRGLRQLAAALEKRHPGL
                     HASVLPCDLADETSLNTLISRLDSLPPGRTLLINNAGAGDYGDFADGRWEKIRSLLRLN
                     VESLTRLCHALIPVMKRNGGDIINLSSLGALLPIPDFAVYAATKAYVSSLSEALRLELR
                     EHGIRVMAVCPGPVSTGFGKAARRPGFTGNMMPGRNAFDTSVETVVKDSLRALARGRAR
                     VFPGMKIRLAAMLLAAAPLGLIRLFMGRRPRKVLPASNDSPSSAS"
     protocluster    1..6862
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[2373:3273]"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2374..3273
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..6862
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..6862
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene"
                     /region_number="1"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /tool="antismash"
     aSDomain        106..480
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg101_1_PKS_KR.1"
                     /evalue="2.50E-08"
                     /label="ctg101_1_PKS_KR.1"
                     /locus_tag="ctg101_1"
                     /protein_end="160"
                     /protein_start="35"
                     /score="25.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="AALEKRHPGLHASVLPCDLADETSLNTLISRLDSLPPGRTLLINN
                     AGAGDYGDFADGRWEKIRSLLRLNVESLTRLCHALIPVMKRNGGDIINLSSLGALLPIP
                     DFAVYAATKAYVSSLSEALRL"
     CDS             801..2372
                     /locus_tag="ctg101_2"
                     /transl_table=11
                     /translation="MKAHRRGIPRLTWFKLAVCLCLAAMAVSLFTPYPAQIIRALKGEP
                     EQAPPDSGTCPPQESPPAEQPGQEEQPITAVPSASGKEPGDERLYTPWTPERTIALPPV
                     QYPPFPPVLPTRPAEGAMTHIYELARGLNLKTQVNFQPGTLASRDRETKSNYQMTLSLN
                     VKQPKALTKKEDILKLNPKLEPMLPGLSTLFRHARVSPYYGQVYVRKQTEIRKNLASLL
                     KLLDRHNYYDTETILETAYPDTGRKLLWLQSEMDVVSDGSDGDRLAAMPDKILKSSFYQ
                     PSTSYRWKKRTDKPNPLLNPWQQRLASYKKTLEKAPAAEKTALRRKIDHAERVIEELKR
                     YSFLISEYDPFIVVPLGVVNQSSPFSPQFGDYAVVIVGDKLYPALVGDAGPRYKTGEGS
                     LRLSREINPKAGPYSRPVSDLKVSYLIFPGSAEPEAGPPDYEKLTDRCRELLNEIGGMG
                     KGFKLHQWEDLLAPKPPPAPKPESGGTAETSADKRKKEEAPGNKPAPAPASPQTAPASS
                     AAKSAA"
     CDS             complement(2374..3273)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg101_3"
                     /sec_met_domain="phytoene_synt (E-value: 1.3e-18, bitscore:
                     55.5, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGLDHLLSAVSRSFYLSMRFLPREMRSGVAVGYLLARATDTVAD
                     AVDMDCRERLALLRMMGETVAGSASREVAATCFGRLGVLSTIQTHRGEAELLARFPECL
                     ALLENLSPHERMLVRQVLASIVEGQAWDLMYFESHAAVSCPEQLEHYTYMVAGCVGEFW
                     TRLGLLAQGPGFSTQPEEQLLRWGRHYGMGLQLVNILRDREEDLARGRSYLPAPDDRPW
                     LDRAERWLKEGVFYAESLRNGRLRFSTVLPAWLGLDTLELLQRADRRHPSSGKVKIARG
                     DVYFRMWKAFLFSWKEAL"
     CDS             complement(3270..4796)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 427.3; E-value:
                     1.3e-129)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg101_4"
                     /transl_table=11
                     /translation="MNEINRSPDLEMVVLKEISSAIVNERNGTALLRHILDVLYRRMKM
                     LRGTFTIRRGNDLMIEASHGLDEQEMKRGHYHVGEGITGHVAETGRPHVIEDISRDSRF
                     LNRTRTRKSGEKVAFICVPIIHLQQVIGTLSIDRAVDRDTDLERDQKLLEIVGNIVGDA
                     LAASLQAHEEHAALVAENEKLRELLTTNPGELIGNCSTMLQVYEQIRQVAPSDATVLIR
                     GSSGTGKELVARAVVNLSGRKDKPLVTLNCAAMPENLLESELFGHEKGSFTGATSRRIG
                     RAEAADGGTLFLDEIGDLSLQMQVKLLRFLQEKTFSRVGSNRELHADVRFIAATSRNLE
                     ELMAANKFREDLYYRLNIFPIVMPDLSKRKGDVMLLAEHFLSKFNLKYGKDIKRLSTPA
                     INMLMAYHWPGNVRELENCMERAVITAQDDCIYGYNLPASLQMPSHDVPYSRDGEAPAD
                     LPTMVDSFERELIVAALKRSPGNMSAAARELGISPRVLHYKMHRLGLQKS"
     CDS             complement(4994..6781)
                     /locus_tag="ctg101_5"
                     /transl_table=11
                     /translation="MNSPSPQSQPPDSVWYGWILKLFHHWKVGERQVTYVWAVLVGMVG
                     SCMSLFFEWMVEVIQWMLTGIWSDSRVGTFSLVEPEWRMFIPVAGGLVAGCILLFLKKR
                     MPGQATEYMEAMSIGNGLIKFRASALKVFSAAWSIASGAAIGKEGPIIQSSALIASTVG
                     QRLHVSIPRLRLLVGCGAAAGFTTAFHAPFSGCLFVSEIIIGTVSMDILAPLLIASCTG
                     FVMLHLLGDPTPLYSSPFESFTVFSQSLWCIALGAAAAVAARGWVCLLDAAARYLNGRQ
                     SLLPLRLAAAGLVVGILAVFYPEVVGNGQALITGLVHEDYGTREALVLLLVKVSAVAVV
                     FGCGTVGGAMTPTLYVGSMVGFIFSTVLTSLGMEGNHTVAYAMVGMASFFAVAAQAPLT
                     ALVMVVEFSMSGQMIYPLLIGVVSAYGTGKLIRARSMYAASLAGSPASVVSLPMAQVHV
                     HDLARHVVPQVAPDASLDDVSSLMLRNPGDLVFVVNKDGTYEGAIYPEDFLAVRRQMEE
                     RKGAAPADAGSLVRTGAPVLDAGTHLTDALKLFEQTHLPAFPVVWKNTGRLDGVLYRNA
                     LFQVITEMMKRESGGDVGM"
ORIGIN
        1 tgtgtttttg acagccttgc cgcctgcatc tttggccccc gacagggtgc gggaaatctc
       61 tcttttttct ttcaccttcc gggccgtggc ctgcgccagc ttgccgccgc cctggaaaaa
      121 cgccatcccg gccttcacgc ctccgtcctt ccctgcgacc tggcggacga aacctccctg
      181 aatacgctca tttcacgcct ggacagcctt cctccgggaa gaacccttct gattaacaac
      241 gccggagccg gtgattacgg agattttgcg gacggccgct gggaaaaaat acgttccttg
      301 ctgcgtctga acgtggaaag cctcacccgc ctgtgccatg cgctgatccc cgtcatgaag
      361 aggaacggag gggatatcat caacctcagt tccctgggag ccctcctgcc cattccggat
      421 tttgccgttt atgcggccac caaggcttat gtttccagcc tgtcggaagc gctgcggctg
      481 gaactgcgcg aacacggcat ccgcgtgatg gccgtctgcc ccggcccggt ttccacaggc
      541 ttcgggaaag cggcgcgccg ccccggcttc accggaaaca tgatgccggg gcgcaatgct
      601 tttgacacgt ccgttgaaac cgtcgtgaaa gacagcctcc gcgccctggc ccgcggacga
      661 gcccgggtct ttcccggcat gaaaatacgg ctggccgcca tgctgctggc tgccgccccg
      721 ctggggctga tacgcctttt catgggcaga cgtccccgga aagtcctgcc ggcatccaat
      781 gattctcctt cttcagcatc atgaaagcgc accgccgcgg aataccccgc ctcacctggt
      841 tcaagctcgc agtctgcctc tgcctggcag ccatggctgt ctccctgttc acgccgtacc
      901 ccgcccagat catacgcgcc ctgaaagggg agccggaaca ggcgccgccg gattccggaa
      961 cctgtccgcc ccaggaatcc ccccccgcgg aacagcccgg gcaggaagaa cagccaataa
     1021 ccgctgtgcc atctgcctcc ggaaaggaac ccggggatga acggctgtac actccatgga
     1081 cgccggagcg cacaatcgcc cttcccccgg tgcagtaccc cccatttcct cccgtgcttc
     1141 ccacaaggcc cgcggaaggg gccatgaccc atatttatga actggcccgc ggcctgaacc
     1201 tgaaaacgca ggttaatttc caacccggca ccctggcctc cagggacagg gaaaccaaaa
     1261 gcaattacca gatgaccctt tccctgaacg tcaaacagcc caaagcattg acgaaaaagg
     1321 aagacattct gaagctcaat ccgaaactgg aacccatgct tcccggcctg tccaccctgt
     1381 tcaggcatgc gcgcgtctcc ccttattacg ggcaggttta cgtccgcaaa cagacggaaa
     1441 tccgtaaaaa cctggcctcc ctgctcaaac ttctggaccg ccataattat tacgatacgg
     1501 agaccattct ggaaaccgcc tatccggaca cgggaaggaa gcttctctgg ctgcaaagtg
     1561 aaatggatgt tgtttccgac ggctcggacg gggaccggct ggccgccatg ccggataaaa
     1621 tcctgaaaag ctccttctat cagcccagca cttcctaccg ctggaaaaag cgcacagaca
     1681 agcccaatcc cctgctcaac ccctggcagc agaggctggc ctcctacaag aagacgctgg
     1741 aaaaagcccc cgccgcggaa aaaacggctc tgcgccgcaa aatagaccat gcggaacggg
     1801 tcattgagga actgaagcgg tacagcttcc tgatctcgga atacgatccg ttcatcgtgg
     1861 ttccgctggg agtcgtcaac cagtcctctc ccttctcccc gcagttcggg gactatgccg
     1921 tcgtcatcgt gggagacaag ttgtacccgg ccctggtggg agacgccggg ccgcgctaca
     1981 aaactgggga ggggtccctg cgcctgagcc gtgaaatcaa ccccaaggcg ggcccttaca
     2041 gccgccccgt ctccgacctg aaggtaagtt acctgatttt tcccggttcc gcagagcctg
     2101 aggccggccc acccgactat gaaaaactta cggacagatg ccgggaactt ctcaacgaaa
     2161 taggcggcat ggggaaagga ttcaaactcc accaatggga agacctgctg gcgcccaagc
     2221 cgccgcccgc cccaaaaccg gaaagcggcg gcacagcgga aacatccgcg gataagcgga
     2281 aaaaggagga agcccccggg aacaagcccg cgccggcccc ggcttccccg caaactgcac
     2341 cggcttcatc agccgcaaaa agcgccgcat aagctacaga gcctccttcc aggaaaaaag
     2401 aaaggctttc cacatccgga aataaacgtc tccgcgcgca atcttcacct tcccggaaga
     2461 cggatgccgc cgatccgccc gctggagcaa ttccagcgtg tccagcccca gccaggcggg
     2521 caggacagtg gaaaaacgca gccgcccgtt ccgcagagat tccgcgtaaa acaccccttc
     2581 cttcagccag cgttccgcac ggtccagcca tggacggtca tctggggcgg gcaagtagct
     2641 tcttccgcgg gcgaggtctt cctcccggtc acgcagaata ttcaccaact gcagccccat
     2701 gccgtagtgc ctgccccagc gcaaaagctg ctcctccggc tgcgtgctga agcccggccc
     2761 ctgagccagc aaacccagcc tggtccagaa ttcccctacg cagccggcca ccatgtaagt
     2821 ataatgttcc agctgttccg gacatgagac ggcagcatgg ctttcaaaat acatcaaatc
     2881 ccacgcctgt ccctccacga tggaggccag cacctgccgc accagcatcc gttcatgcgg
     2941 ggaaaggttt tccagaagcg ccaggcattc gggaaaacgg gccagcaatt ccgcctcccc
     3001 ccggtgcgtc tggattgtgg aaagaacgcc cagacggcca aaacaggtgg cggcaacctc
     3061 ccgggaggca gagccggcca ccgtctcccc catcatcctc aaaagcgcca ggcgctcccg
     3121 gcaatccata tccacggcat ccgccaccgt atccgtggca cgcgccagca gatagcccac
     3181 ggccacgccg gagcgcattt cccggggcag gaagcgcatg ctcagataaa aggaccggga
     3241 gacggccgat aaaagatggt caaggccttt catgatttct gcaggcccag cctgtgcatc
     3301 ttataatgga gtactcgcgg ggaaatgccc agttcccggg ccgcggcgga catattgccc
     3361 ggagaacgtt tcaatgcggc tacaatcaat tcccgttcaa aggaatctac catggtcggc
     3421 aaatcggcag gagcctcccc gtcacgggaa taagggacgt catggctggg catctgaagg
     3481 gaggcgggaa ggttgtaacc gtaaatgcag tcgtcctgcg ccgtaatgac ggcacgttcc
     3541 atgcagtttt ccagctcccg gacgttgccg ggccagtggt aagccatgag catgttgatg
     3601 gcgggggtgg acagccgttt gatgtccttt ccgtatttca ggttgaactt ggaaagaaaa
     3661 tgttccgcca gcagcatgac gtcccccttg cgtttggaga ggtccggcat aacgatgggg
     3721 aaaatgttca accggtaata caagtcttcc cggaacttgt tcgccgccat caattcctcc
     3781 agattgcggc tggtggcggc gatgaagcgc acgtctgcat gaagctccct gttgcttccc
     3841 acgcgggaaa aggtcttttc ctgaagaaag cgcagcagct tcacctgcat ctgaaggctt
     3901 aaatccccga tttcatccag aaacagggtg ccgccgtccg ccgcctccgc ccggccgatg
     3961 cggcggctgg tggccccggt aaaagaaccc ttttcatgac cgaacagctc gctttccagc
     4021 aggttctccg gcatggccgc acaattcagc gtgaccagcg gcttatcctt tctgccgctc
     4081 agattcacca cggcgcgcgc caccagttcc ttccccgttc cggaacttcc ccgtatcagc
     4141 accgtggcat cgctgggcgc cacctggcgg atctgttcat acacctggag catagtgctg
     4201 caattgccaa tcaattcgcc cggattagtc gtcaaaagct cccgcagttt ttcattttcc
     4261 gcaaccaggg cggcatgttc ctcatgcgcc tggaggctgg cagccagagc atccccaaca
     4321 atattgccta caatctccaa cagtttctga tcccgttcca ggtcggtgtc ccggtccacg
     4381 gcacggtcaa tgctcaacgt gccgatgacc tgctgcaaat gaatgatggg aacgcagatg
     4441 aaggctactt tttcaccgct tttgcgcgtg cgagtacggt tcaggaacct ggaatcccgg
     4501 gaaatatcct caatcacatg gggcctgccc gtttccgcca catgccccgt aatgccttcc
     4561 cccacatggt aatggccgcg tttcatttcc tgctcgtcca ggccgtggga ggcttcaatc
     4621 atcaaatcgt tcccgcggcg gatggtgaac gtgccgcgca gcattttcat gcggcggtaa
     4681 agcacgtcca gaatatgccg gagcaaagcc gtgccgttgc gttcattgac aatggcggag
     4741 ctgatttctt tcagcacgac catctccaaa tccggtgacc tgtttatttc attcatgcaa
     4801 tccggggctg ggcgaatatt aaccgcacgc ccccgccata ccaacaactt tttcttccac
     4861 cgccatgcag ccgggcaaaa aaacggtacg gggaatatgg ataacatccc agcaattaat
     4921 gttgatgata ttacgaacgg ggaacaaaag atttttacaa aaatgtaata tacatccctt
     4981 gtttcgttcc gttttacatg cccacgtctc cgccggactc ccgtttcatc atctccgtga
     5041 taacctggaa caacgcgttg cggtacagca cgccgtccag ccgaccggta ttcttccaga
     5101 ccacgggaaa ggctggcaga tgggtttgtt caaacagctt caaggcatcc gtcagatggg
     5161 tgccggcgtc cagcacggga gcgcccgtac ggaccaggga cccggcatcg gccggggccg
     5221 cccccttccg ctcctccatc tgccggcgaa ccgccagaaa gtcctccgga tagatggccc
     5281 cttcataagt tccatcctta ttcaccacaa aaaccagatc tccgggattc cgcagcatca
     5341 gggaagagac atcatccagg gaagcatccg gggccacctg gggcaccacg tgccgcgcca
     5401 ggtcatgcac atggacttgc gccatgggca gactgacgac ggacgccgga ctgccggcca
     5461 ggctggcggc atacatggaa cgcgcgcgaa tcagttttcc cgtgccataa gcgcttacga
     5521 caccgatcag caagggataa atcatctgtc cgctcatgga aaactccacc accatcacca
     5581 gagccgtcag gggggcctgg gcagctacgg cgaaaaagga cgccataccc accatcgcat
     5641 acgccaccgt atggttgccc tccattccca gggacgtcag aaccgtactg aagataaaac
     5701 ccaccatgct ccccacgtac agggtgggcg tcatggctcc ccccaccgtg ccgcagccga
     5761 acaccaccgc cacggcagac accttcacca gaagcaggac gagcgcctcc cgcgtgccgt
     5821 aatcctcatg gaccagcccg gtaatgagag cctgaccgtt gcccaccact tccggataaa
     5881 aaacggccag aatccccacg accagcccgg cggccgccaa tcgcagcggc agaagggact
     5941 ggcggccatt caaatatctg gcggccgcat ccagcaaaca gacccatccc ctggccgcca
     6001 cggccgccgc cgcccccagg gcgatgcacc agagagactg ggaaaagaca gtaaagcttt
     6061 caaacgggga actgtacaaa ggggtgggat cccccagcag atgcagcatc acgaacccgg
     6121 tacaggaggc gataagcagg ggggccagaa tatccatgct cacggtgccg atgataattt
     6181 cactcacgaa caggcagccg gaaaaagggg catggaacgc cgtcgtgaat ccggctgccg
     6241 ctccgcagcc gaccagcaac cggagccgcg gaatggatac atgcagacgc tgccccacgg
     6301 tagacgcaat cagggcggaa gactggatga taggcccttc cttgccgatg gccgcgccgg
     6361 aagcgatgct ccatgccgcg gaaaaaactt tcagggcgga ggcccggaac ttgatcagcc
     6421 cgttcccgat ggacatggcc tccatatatt ccgtagcctg ccccggcatc ctcttcttca
     6481 ggaatagcag aatgcagccg gccaccaggc cgcccgccac cggaataaac atgcgccatt
     6541 ccggctccac cagggaaaag gttcctacgc gggaatccga ccagatgccg gtgagcatcc
     6601 actggatcac ttccaccatc cactcgaaaa acagagacat gcaggagccc accatgccga
     6661 cgagaacggc ccatacataa gtaacctgcc tttcccccac cttccaatga tggaacagtt
     6721 ttaaaatcca tccgtaccag acggaatccg gcggctggga ctggggggac ggagaattca
     6781 tggaaaagaa ggcaatacta ttccattgtg acaaaaaaat acctccggct gttcgatacg
     6841 ggagaaaaaa ctgcccagcc cc
//
