LOCUS       gnlProkkaBFLOGHPP_71    4065 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BFLOGHPP_71.
ACCESSION   gnlProkkaBFLOGHPP_71
VERSION     gnlProkkaBFLOGHPP_71
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 15:15:11
            Original ID  :: gnl|Prokka|BFLOGHPP_71
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4065
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4065
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[1033:3232]"
                     /cutoff="5000"
                     /detection_rule="(hr-t2pks-ksa and (t2fas or APE_KS2 or
                     ketoacyl-synt))"
                     /neighbourhood="20000"
                     /product="HR-T2PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1034..3232
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(hr-t2pks-ksa and (t2fas or APE_KS2 or
                     ketoacyl-synt))"
                     /neighbourhood="20000"
                     /product="HR-T2PKS"
                     /protocluster_number="1"
     cand_cluster    1..4065
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(hr-t2pks-ksa and (t2fas or APE_KS2 or
                     ketoacyl-synt))"
                     /kind="single"
                     /product="HR-T2PKS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..4065
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="HR-T2PKS"
                     /region_number="1"
                     /rules="(hr-t2pks-ksa and (t2fas or APE_KS2 or
                     ketoacyl-synt))"
                     /tool="antismash"
     CDS             63..749
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1141:acyltransferase (Score: 82.3; E-value: 5.4e-25)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg71_1"
                     /transl_table=11
                     /translation="MEYNYHKNAGQLAFIKFVKGLVHLLIRPKVEWKDKSLKKSLKGNP
                     VVFVCNHTHHFDGVVISSVLSRYKPYMLVKKSWYDKSGTGSFIRIWRSIPVDFDTMDTN
                     WYAQSEGAVENGYSMLIFPEGGIAREGKMLPFKPGAALLAAKKGLDIIPIASLGEYKIL
                     FGKRQKILIGNPIKSECPENVRCSKYAKEISAEAEKQVKKLYLELEEKYGKGKVYYKED
                     FSSENL"
     CDS             790..1032
                     /NRPS_PKS="Domain: PP-binding (6-75). E-value: 1.1e-11.
                     Score: 37.0. Matches aSDomain:
                     nrpspksdomains_ctg71_2_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg71_2"
                     /sec_met_domain="PP-binding (E-value: 9.6e-13, bitscore:
                     37.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNAIADQIKEMLVENLRIPENILTYDSELFGDEIGLDSIDSIEI
                     VAGIDTLFGIDMTGADREHFQSIRALTEYVESKQG"
     aSDomain        808..1014
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg71_2_PP-binding.1"
                     /evalue="1.10E-11"
                     /label="ctg71_2_PP-binding.1"
                     /locus_tag="ctg71_2"
                     /protein_end="75"
                     /protein_start="6"
                     /score="37.0"
                     /tool="antismash"
                     /translation="DQIKEMLVENLRIPENILTYDSELFGDEIGLDSIDSIEIVAGIDT
                     LFGIDMTGADREHFQSIRALTEYV"
     CDS             1034..3232
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (67-399). E-value:
                     7.5e-50. Score: 161.9. Matches aSDomain:
                     nrpspksdomains_ctg71_3_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     HR-T2PKS: hr-t2pks-ksa"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     HR-T2PKS: t2fas"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 82.3; E-value:
                     6.1e-25)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg71_3"
                     /sec_met_domain="hr-t2pks-ksa (E-value: 1.9e-106, bitscore:
                     344.7, seeds: 7, tool: rule-based-clusters)"
                     /sec_met_domain="t2fas (E-value: 1.6e-23, bitscore: 71.5,
                     seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADKKRCVVTGLGLICGVGDNVKDCWDAVTLGHSGIDEVKSVDTS
                     NCYAHKGAEVDKASSELSPENYDRSSLLCIHAANEAFEDANIDASEKNIGVILGSCVGG
                     AASIDKYYTDEIKGDGGKKEDIFKMGASAIANNVSAHFGLEGITANIVNACAAGTMSIG
                     YACDLIREGKGDVFIAGGSDSFSSLAFSGFHALHALDENACSPFNHSTGITLGEGSGIL
                     VIESYEHAVERGAKIYCEILGSGVSSDAYHITAPRPDGEGQMSAIRRAVESSALSFDDI
                     DYINAHGTGTAKNDEAEFLSLHTLFDGNDHLSVSSTKSMTGHCLGAAGSIEAVFSVKAI
                     KENLVPPTIGYSDEDLKVLSEKAGNIDFIPNKSHIKDVHYAMSNSFAFGGNNASIIFSD
                     NEHDIPDNSKNEKIYITGISKLTGTKTDEHSLNCNLTSEDYDKHGIKVAFYRKLDRFSQ
                     LQLLSGMDALADADIKIDKDNEYKTGIVIGTADGPMTEIVDFQKKAITRGTEKGSAFSF
                     PNTVYNAAGGYLSIFSGIKGYNATVANGNQAGLQSICYAADILADGNESVMLAAGTDEN
                     TKTNLELYTKAELLEKPLGEGSVTLVLETEESANGRNARKYAEIKGYAQAHRPVSYDNS
                     EVDSKAVVEVIEKACVNAGIEADDIDFVCCDDRKIIKTLMPCYDVSQEIGNARAAASAM
                     TAAYAAELLSDSEKNYEYGLALSMGAGGTYSAVILRKA"
     aSDomain        1235..2230
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg71_3_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="7.50E-50"
                     /label="ctg71_3_PKS_KS.1"
                     /locus_tag="ctg71_3"
                     /protein_end="399"
                     /protein_start="67"
                     /score="161.9"
                     /tool="antismash"
                     /translation="DRSSLLCIHAANEAFEDANIDASEKNIGVILGSCVGGAASIDKYY
                     TDEIKGDGGKKEDIFKMGASAIANNVSAHFGLEGITANIVNACAAGTMSIGYACDLIRE
                     GKGDVFIAGGSDSFSSLAFSGFHALHALDENACSPFNHSTGITLGEGSGILVIESYEHA
                     VERGAKIYCEILGSGVSSDAYHITAPRPDGEGQMSAIRRAVESSALSFDDIDYINAHGT
                     GTAKNDEAEFLSLHTLFDGNDHLSVSSTKSMTGHCLGAAGSIEAVFSVKAIKENLVPPT
                     IGYSDEDLKVLSEKAGNIDFIPNKSHIKDVHYAMSNSFAFGGNNASIIFSD"
     CDS             3248..3982
                     /NRPS_PKS="Domain: PKS_KR (3-167). E-value: 2.7e-16. Score:
                     51.8. Matches aSDomain: nrpspksdomains_ctg71_4_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     227.2; E-value: 3.6e-69)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg71_4"
                     /sec_met_domain="adh_short (E-value: 1.2e-40, bitscore:
                     127.8, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 2.4e-35, bitscore:
                     111.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTALVTGSSRGIGKACALKLAELGYDIAVNCNSNLEMAQKAVD
                     EITSLGRKAVAYKANTADIDEVKDMFRSIQQDFGGIDVLVNNAGVVDDAYLLMIKDESL
                     ERSLDINIKGYFNCARQASLKMLRKKSGIIINISSVSSVLAVEGQSVYSATKGAVNAMT
                     HTLAKELAKYGIRVNAVAPGFIETEMMNGIPEELQKKYLEAIPEKRFGTVQDVANVVGQ
                     LCSDDFSYMTGQVLVLDGGLSL"
     aSDomain        3257..3748
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg71_4_PKS_KR.1"
                     /evalue="2.70E-16"
                     /label="ctg71_4_PKS_KR.1"
                     /locus_tag="ctg71_4"
                     /protein_end="167"
                     /protein_start="3"
                     /score="51.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TALVTGSSRGIGKACALKLAELGYDIAVNCNSNLEMAQKAVDEIT
                     SLGRKAVAYKANTADIDEVKDMFRSIQQDFGGIDVLVNNAGVVDDAYLLMIKDESLERS
                     LDINIKGYFNCARQASLKMLRKKSGIIINISSVSSVLAVEGQSVYSATKGAVNAMTHTL
                     A"
     CDS             3979..4065
                     /locus_tag="ctg71_5"
                     /transl_table=11
                     /translation="MMNLLEINQRIKQRPPFQMIERVTELEPN"
ORIGIN
        1 atttgaccgt tgaatttttt taaaataaaa atataatatt ctaaaaaacg agggtaaaga
       61 gtatggagta caattatcat aaaaatgcag gacagcttgc attcataaaa tttgtaaaag
      121 gtcttgtgca tcttcttatt cgcccgaagg ttgaatggaa agacaagagc cttaaaaaga
      181 gcctcaaggg caatcctgtt gtgtttgtgt gcaaccacac tcaccacttt gacggagttg
      241 tgataagctc tgtactcagc agatacaagc cgtatatgct tgttaaaaaa agctggtacg
      301 acaagagcgg aacaggctcg tttatccgaa tttggcgcag tattcccgtt gactttgaca
      361 ccatggacac aaactggtat gcgcaaagtg agggtgcggt tgaaaacgga tattcaatgc
      421 ttatcttccc cgagggcgga attgcaagag agggcaaaat gctcccgttc aagcccggtg
      481 cggcattgct tgcggcaaaa aaaggtcttg acataatccc gattgcatct ttgggtgagt
      541 ataaaattct ttttggaaag aggcagaaaa ttttaatcgg caatccgata aaatccgaat
      601 gtcccgaaaa tgttcgctgc tcaaaatatg caaaagaaat aagtgccgag gccgaaaagc
      661 aggtcaaaaa gctttatctt gagcttgaag aaaaatacgg caaaggcaag gtttattaca
      721 aagaagattt ttcttcggaa aatttataat aaaatcaaaa aaatcaaaat tttaagtgag
      781 gtaattaaaa tgaacaatgc tattgcagat cagattaagg aaatgctcgt agaaaacctt
      841 agaattcccg aaaacattct tacatacgat tcagaacttt tcggtgacga aatcggtctt
      901 gactcaatcg actcaatcga aatcgttgca ggcatcgaca cacttttcgg tattgatatg
      961 acaggtgcag accgtgagca cttccaatca atcagagcac ttacagaata tgtagaaagc
     1021 aagcagggtt aatatggctg acaaaaagag atgtgttgtc acaggactcg gacttatctg
     1081 cggcgtcggt gacaatgtaa aggattgctg ggatgccgta acactaggtc actccggcat
     1141 tgatgaggtt aagtcggttg acacctcaaa ctgttatgca cacaagggtg cagaggttga
     1201 caaggcatcg tcagagcttt ctcccgaaaa ctatgaccgt tcttcccttc tctgtattca
     1261 tgccgcaaac gaggcttttg aagatgcaaa cattgacgca tccgaaaaga acatcggtgt
     1321 tattcttggc agttgtgtag gcggtgcggc aagcattgac aaatattaca cagacgaaat
     1381 caagggtgac ggcggtaaaa aagaagatat tttcaaaatg ggtgcttcgg caattgccaa
     1441 caatgtttcc gctcatttcg gacttgaggg cattaccgca aacatcgtca acgcttgtgc
     1501 ggcaggcaca atgagcatcg gctatgcctg tgaccttatc cgtgagggca agggtgatgt
     1561 gttcatcgca ggcggttcgg acagcttttc ttcacttgca ttcagcggtt tccacgctct
     1621 ccatgcgctt gacgaaaacg cctgttcccc gttcaatcac agcacaggta tcacgctcgg
     1681 cgagggttcg ggtattcttg taatcgaaag ctacgaacac gctgttgaac gaggcgcaaa
     1741 gatttactgt gaaattctcg gttcgggtgt aagcagtgac gcttaccaca ttaccgcacc
     1801 ccgtcccgac ggtgaaggtc agatgagtgc aatcagaagg gctgtggaaa gctctgctct
     1861 tagtttcgac gatatcgact acataaacgc acacggaacg ggtactgcca aaaatgacga
     1921 ggctgaattt ctttcacttc acacactttt tgacggcaac gaccaccttt ctgtcagctc
     1981 aacaaaatct atgacaggtc attgcctcgg tgcggcaggt tcaattgagg ctgtattttc
     2041 cgtaaaagca ataaaagaga acctcgttcc ccctacaatc ggctactccg atgaggattt
     2101 gaaggtgctt tccgaaaagg cgggcaacat tgactttatt ccgaacaaga gccacataaa
     2161 agatgttcac tatgcaatgt caaactcatt tgcattcggc ggcaacaacg caagcatcat
     2221 tttctcggac aacgagcatg atattcccga caacagtaaa aatgaaaaaa tttacattac
     2281 gggcatttca aagcttacag gcacaaagac tgacgaacac agccttaact gcaatcttac
     2341 ctccgaggat tatgacaaac acggaatcaa ggttgcattt tacagaaagc ttgaccgttt
     2401 cagccagctc cagcttttga gcggtatgga cgcacttgca gacgctgaca ttaaaattga
     2461 caaagacaac gaatataaaa caggtattgt aatcggcacg gctgacggcc ctatgaccga
     2521 aattgttgat ttccagaaaa aggcaatcac aagaggcacc gaaaagggca gtgctttttc
     2581 attcccgaat acggtttaca atgccgcagg cggttatctg agcattttct caggtatcaa
     2641 gggctacaac gcaactgttg caaacggcaa tcaggcagga ctgcagagta tttgctatgc
     2701 cgctgatatt cttgcagacg gcaacgaaag cgttatgctt gccgcaggta ccgatgaaaa
     2761 tacaaagaca aaccttgaac tctatacaaa ggccgaattg cttgaaaagc cgctcggtga
     2821 gggctctgta actctcgttc ttgaaacaga ggaaagtgca aacggcagaa atgcacgcaa
     2881 gtatgcagaa attaagggtt atgcacaggc tcaccgccct gtatcttatg acaactcaga
     2941 ggttgacagc aaggctgttg ttgaggttat cgaaaaggct tgtgtgaatg ccggcatcga
     3001 ggcagacgat atcgactttg tatgctgtga cgacaggaag attatcaaga cgcttatgcc
     3061 ctgctatgat gtatcgcagg aaatcggcaa tgcaagagcc gcagcaagcg caatgacagc
     3121 ggcatatgcg gctgagcttc tttctgacag cgagaaaaat tacgaatacg gacttgctct
     3181 ttcaatgggt gcgggcggaa catactctgc tgtaatcctg aggaaagcgt aaaaatcgga
     3241 ggtaaatatg agcaaaaccg ctcttgtaac aggttcatca aggggcattg gcaaggcttg
     3301 cgctttaaag cttgcagagc ttggatatga cattgccgtg aactgcaatt caaatttaga
     3361 aatggctcaa aaggctgttg acgaaattac atcactcggc agaaaagccg ttgcctacaa
     3421 ggcaaacacg gcagatattg acgaagtaaa ggatatgttc cgcagtattc agcaggactt
     3481 cggcggaatt gatgtgcttg tcaacaacgc aggtgtggtt gacgacgctt accttttgat
     3541 gattaaagac gagtcgcttg aaagaagtct tgacattaat atcaaaggat atttcaattg
     3601 tgcaagacag gcatcgctta aaatgctccg caaaaagagc ggaatcatca tcaacatttc
     3661 ttccgtaagc tctgttcttg cagttgaagg tcagtcggtt tacagtgcaa caaagggtgc
     3721 ggtaaacgct atgacacaca cgcttgcaaa ggaacttgca aagtacggaa tcagagtaaa
     3781 cgcagttgca cccggtttta tcgaaaccga aatgatgaac ggcattcccg aagaattgca
     3841 aaaaaagtat cttgaggcta ttcccgaaaa gagattcggc acagttcagg atgtcgcaaa
     3901 tgtagtcgga cagctttgca gtgacgattt ttcatatatg acaggtcagg tgcttgtgct
     3961 tgacggagga ctcagcttat gatgaatctg cttgaaatca atcagagaat aaaacaaaga
     4021 ccaccctttc agatgattga gagggtgacc gagcttgagc cgaat
//
