LOCUS       gnlProkkaBHFMIGBI_63   10362 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BHFMIGBI_63.
ACCESSION   gnlProkkaBHFMIGBI_63
VERSION     gnlProkkaBHFMIGBI_63
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 15:14:55
            Original ID  :: gnl|Prokka|BHFMIGBI_63
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10362
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10362
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[5104:7303]"
                     /cutoff="5000"
                     /detection_rule="(hr-t2pks-ksa and (t2fas or APE_KS2 or
                     ketoacyl-synt))"
                     /neighbourhood="20000"
                     /product="HR-T2PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5105..7303
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(hr-t2pks-ksa and (t2fas or APE_KS2 or
                     ketoacyl-synt))"
                     /neighbourhood="20000"
                     /product="HR-T2PKS"
                     /protocluster_number="1"
     cand_cluster    1..10362
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(hr-t2pks-ksa and (t2fas or APE_KS2 or
                     ketoacyl-synt))"
                     /kind="single"
                     /product="HR-T2PKS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10362
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="HR-T2PKS"
                     /region_number="1"
                     /rules="(hr-t2pks-ksa and (t2fas or APE_KS2 or
                     ketoacyl-synt))"
                     /tool="antismash"
     CDS             117..308
                     /locus_tag="ctg63_1"
                     /transl_table=11
                     /translation="MKYPELSCNVYAEVDGENVLLIEIDREGRAKVYHENLRIDGVQKI
                     FEEINCNIESYIKYFGTK"
     CDS             complement(375..824)
                     /gene_functions="regulatory (smcogs)
                     SMCOG1171:transcriptional regulator, MerR family (Score:
                     81.3; E-value: 1.9e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg63_2"
                     /transl_table=11
                     /translation="MYTIGQVSQMCGIPVSTLRYYDKEGLFPHMERVSGIRRFSDRELE
                     TLRIIDCLKKSGLEIREIRKFMQWCAEGSSSYPQRRELFENQKKTVEKEIERLQKTLDM
                     LRFKCWYYDTAIADGNEDRINEMLPNNLPDDIQKLYDHAHSDDED"
     CDS             complement(975..1514)
                     /locus_tag="ctg63_3"
                     /transl_table=11
                     /translation="MKKQLMIFDFVYTGIAAILLLTIAILQNCGINITHENVIGIIVLI
                     ILFVLILLSTVNVLGCNYPTSKITFLRPILLFIALYIFYCMPFMGFIGKAGNVWNSIMF
                     AHFGITVSRQFYYISKSPIAEKFVKSPFVYTKGTEFFSSAGSFFKFLSVIIIPMTVIGI
                     ILNITTNGINVASIFS"
     CDS             complement(1710..2549)
                     /locus_tag="ctg63_4"
                     /transl_table=11
                     /translation="MTGLIIEGGARRGIFTAGITDCLLENKIHFDYVAGVSAGAEVALD
                     FTAKQEGRSRRVIMPHRTGDFSVLGFLSMDLDNMIYRFPYQDYPFDFDTFFASDTNCEF
                     VATDCVTGKAKYFSENKSEQRLLDSVRASCTVPILYQISEFEGGKYVDGSIADAVPFDR
                     AFEQGCSRVLVLLTKPENEPCTDYRKFEFLINKKYKDYPNLINALMTRFDRYNEQCKRM
                     KQLEEDGILMVLRPSHKYVKSFEMNTDVLDEAYNAGKNLAKEKLAEIEDFLNVLEKK"
     CDS             2626..3195
                     /locus_tag="ctg63_5"
                     /transl_table=11
                     /translation="MTDLRIVKTRTNIKNSLIDLLAEKNVSKITVTELAEKAMINRKTF
                     YRHYHTVQDVVDDINYDIVNDVISHAKKSDRDGNNLVNQLNFIGLSIVENKEQINKILK
                     NSPEVFGSGRSVELLKRFIEVSIRPVLNFKNETKLKYLVEFVVSGFISVYVRWFNDGCA
                     ESSEKLADAVNEFVLGALSEYVRPKS"
     CDS             complement(3196..3900)
                     /locus_tag="ctg63_6"
                     /transl_table=11
                     /translation="MKVLVLNGSPKGEKSNTLNITKAFLDGFSADTEVEYITVKKETIK
                     PCMGCFSCWSRTPGKCVIKDDMQKIYEKINSADIIIESFPLYFFGMPSQMKALTDRCLP
                     YMLPYSGNVAEDKEASFHELRDEAMHEKRLLVITTCGYVSAEPMYPALIKQLDLICGNG
                     NYTMIKCPEGELFIAEKAERQRKAYLDSITEAGREFCENRCLCDETMKKISKPILSPKG
                     FEAITKAHWKMS"
     CDS             complement(3903..4358)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1270:UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine
                     (Score: 92.6; E-value: 4.5e-28)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg63_7"
                     /transl_table=11
                     /translation="MMNLLEINQRIKQRPPFQMIERVTELEPNVSATGIKNVSVNEPYF
                     SGHFPDTPIMPGVLLIESAAQLCSLVFAPESVEEDKLYVLLKVKDFKMLRPVIPGDTLI
                     ISVNVTMSTKSAFEFACVIKVDGEVRAKGNLLFTTMDKNAVYKPSQE"
     CDS             complement(4355..5089)
                     /NRPS_PKS="Domain: PKS_KR (3-167). E-value: 2.7e-16. Score:
                     51.8. Matches aSDomain: nrpspksdomains_ctg63_8_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     227.2; E-value: 3.6e-69)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg63_8"
                     /sec_met_domain="adh_short (E-value: 3.1e-40, bitscore:
                     127.8, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 6.2e-35, bitscore:
                     111.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTALVTGSSRGIGKACALKLAELGYDIAVNCNSNLEMAQKAVD
                     EITSLGRKAVAYKANTADIDEVKDMFRSIQQDFGGIDVLVNNAGVVDDAYLLMIKDESL
                     ERSLDINIKGYFNCARQASLKMLRKKSGIIINISSVSSVLAVEGQSVYSATKGAVNAMT
                     HTLAKELAKYGIRVNAVAPGFIETEMMNGIPEELQKKYLEAIPEKRFGTVQDVANVVGQ
                     LCSDDFSYMTGQVLVLDGGLSL"
     aSDomain        complement(4589..5080)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg63_8_PKS_KR.1"
                     /evalue="2.70E-16"
                     /label="ctg63_8_PKS_KR.1"
                     /locus_tag="ctg63_8"
                     /protein_end="167"
                     /protein_start="3"
                     /score="51.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TALVTGSSRGIGKACALKLAELGYDIAVNCNSNLEMAQKAVDEIT
                     SLGRKAVAYKANTADIDEVKDMFRSIQQDFGGIDVLVNNAGVVDDAYLLMIKDESLERS
                     LDINIKGYFNCARQASLKMLRKKSGIIINISSVSSVLAVEGQSVYSATKGAVNAMTHTL
                     A"
     CDS             complement(5105..7303)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (66-399). E-value:
                     4.6e-50. Score: 162.6. Matches aSDomain:
                     nrpspksdomains_ctg63_9_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     HR-T2PKS: hr-t2pks-ksa"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     HR-T2PKS: t2fas"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 80.3; E-value:
                     2.4e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg63_9"
                     /sec_met_domain="hr-t2pks-ksa (E-value: 7.5e-106, bitscore:
                     344.1, seeds: 7, tool: rule-based-clusters)"
                     /sec_met_domain="t2fas (E-value: 4.2e-23, bitscore: 71.5,
                     seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADKKRCVVTGLGLICGVGDNVKDCWDAVTLGHSGIDEVKSVDTS
                     NCYAHKGAEVDKASSELSPENYDRSSLLCIHAANEAFEDASIDASEKNIGVILGSCVGG
                     AASIDKYYTDEIKGDGGKKEDIFKMGASAIANNVSAHFGLEGITANIVNACAAGTMSIG
                     YACDLIREGKGDVFIAGGSDSFSSLAFSGFHALHALDENACSPFNHSTGITLGEGSGIL
                     VIESYEHAVERGAKIYCEILGSGVSSDAYHITAPRPDGEGQMSAIRRAVESSALSFDDI
                     DYINAHGTGTAKNDEAEFLSLHTLFDGNDHLSVSSTKSMTGHCLGAAGSIEAVFSVKAI
                     KENLVPPTIGYSDEDLKVLSEKAGNIDFIPNKSHTKDVHYAMSNSFAFGGNNASIIFSD
                     NEHDIPDNSKNEKIYITGISKLTGTKTDEHSLNCNLTSEDYDKHGIKVAFYRKLDRFSQ
                     LQLLSGMDALADADIKIDKDNEYKTGIVIGTADGPMTEIVDFQKKAITRGTEKGSAFSF
                     PNTVYNAAGGYLSIFSGIKGYNATVANGNQAGLQSICYAADILADGNESVMLAAGTDEN
                     TKTNLELYTKAELLEKPLGEGSVTLVLETEESANGRNARKYAEIKGYAQAHRPVSYDNS
                     EVDSKAVVEVIEKACVNAGIEADNIDFVCCDDRKIIKTLMPCYDVSQEIGNARAAASAM
                     TAAYAAELLSDSEKNYEYGLALSMGAGGTYSAVILRKA"
     aSDomain        complement(6107..7105)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg63_9_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="4.60E-50"
                     /label="ctg63_9_PKS_KS.1"
                     /locus_tag="ctg63_9"
                     /protein_end="399"
                     /protein_start="66"
                     /score="162.6"
                     /tool="antismash"
                     /translation="YDRSSLLCIHAANEAFEDASIDASEKNIGVILGSCVGGAASIDKY
                     YTDEIKGDGGKKEDIFKMGASAIANNVSAHFGLEGITANIVNACAAGTMSIGYACDLIR
                     EGKGDVFIAGGSDSFSSLAFSGFHALHALDENACSPFNHSTGITLGEGSGILVIESYEH
                     AVERGAKIYCEILGSGVSSDAYHITAPRPDGEGQMSAIRRAVESSALSFDDIDYINAHG
                     TGTAKNDEAEFLSLHTLFDGNDHLSVSSTKSMTGHCLGAAGSIEAVFSVKAIKENLVPP
                     TIGYSDEDLKVLSEKAGNIDFIPNKSHTKDVHYAMSNSFAFGGNNASIIFSD"
     CDS             complement(7305..7547)
                     /NRPS_PKS="Domain: PP-binding (6-75). E-value: 1.1e-11.
                     Score: 37.0. Matches aSDomain:
                     nrpspksdomains_ctg63_10_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg63_10"
                     /sec_met_domain="PP-binding (E-value: 2.5e-12, bitscore:
                     37.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNAIADQIKEMLVENLRIPENILTYDSELFGDEIGLDSIDSIEI
                     VAGIDTLFGIDMTGADREHFQSIRALTEYVESKQG"
     aSDomain        complement(7323..7529)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg63_10_PP-binding.1"
                     /evalue="1.10E-11"
                     /label="ctg63_10_PP-binding.1"
                     /locus_tag="ctg63_10"
                     /protein_end="75"
                     /protein_start="6"
                     /score="37.0"
                     /tool="antismash"
                     /translation="DQIKEMLVENLRIPENILTYDSELFGDEIGLDSIDSIEIVAGIDT
                     LFGIDMTGADREHFQSIRALTEYV"
     CDS             complement(7588..8274)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1141:acyltransferase (Score: 82.6; E-value: 4.5e-25)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg63_11"
                     /transl_table=11
                     /translation="MEYNYHKNAGQLAFIKFVKGLVHLLIRPKVEWKDKSLKKSLKGKP
                     VVFVCNHTHHFDGVVISSVLSRYKPYMLVKKSWYDKSGTGSFIRICRSIPVDFDTMDTN
                     WYAQSEGAVENGYSMLIFPEGGIAREGKMLPFKPGAALLAAKKGLDIIPIASLGEYKIL
                     FGKRQKILIGNPIKSECPENVRCSKYAKEISAEAEKQVKKLYLELEEKYGKGKVYYKED
                     FSSENL"
     CDS             8516..9577
                     /locus_tag="ctg63_12"
                     /transl_table=11
                     /translation="MKKVILTGDRPTGRLHVGHYAGSLKERVKLQNSGEYDDIYLMIAD
                     AQALTDNAEHPEKVRQNILQVALDYLACGIDPNKSTIFVQSMIPELTELTFYYMNLVTV
                     SRVQRNPTVKAEIQMRNFEASIPVGFFCYPISQAADITAFRATAVPVGEDQLPMLEQCK
                     EIVHKFNSVYGETLTEPQIILPSNKACLRLPGIDGKAKMSKSLGNCIYLAEEPEDIKKK
                     VMSMFTDPNHLRVEDPGKVEGNPVFIYLDAFCRDEYFAEFWNDYSCLDELKAHYQRGGL
                     GDVKVKKFLNNVMQEELRPIRERRKEWENHLPDVLNILKEGSKVAKETAAKTLEDVRHS
                     MRIDYFTDNNLLK"
     CDS             9747..10361
                     /locus_tag="ctg63_13"
                     /transl_table=11
                     /translation="MIDARKHTLDSVKKLTDYSDFNLYKMDICYDYSIDKIIDRGIFDD
                     ESALGAILQEVLPDYPVNLKMPNFGCSAFTMKNPDSVMMGRNYDFKNDTSSMLVYCSPK
                     NGYRSVAFAALDNVGANNPELSDETRLATLLSPFISLDGINEKGVSIAVLTLDSKPVRQ
                     QSGKPVIATTLAIRLILDRAASTEEAVTLFEKYDMFASSGRD"
ORIGIN
        1 tttctcttac cataactctg cctctttcag tttctaaccc gagtataaca catcgcaaaa
       61 gcgattacaa gttaaattac ataatgtatc ctcatataaa ttaccgaggt ggttaggtga
      121 aatatccgga gttatcgtgc aatgtttatg ctgaggttga cggtgagaat gttttgctga
      181 ttgaaattga cagagagggc agagcaaagg tttatcatga aaatttaaga attgacgggg
      241 tgcagaaaat ttttgaagaa atcaactgca acattgaaag ctacataaaa tatttcggaa
      301 caaaataaaa tagcacaaaa taaaacgccc tccgtttgga gagcgtaatt ctgtgaattt
      361 acaaattatc aaaattaatc ttcgtcatcg ctgtgggcat ggtcatacag cttttgaata
      421 tcatcgggaa gattgttcgg gagcatttcg ttgattctgt cctcgttgcc gtcagcaatg
      481 gcagtatcgt agtaccagca cttaaagcgg agcatatcaa gcgtcttttg aagacgctca
      541 atttcctttt ctacggtttt tttctgattt tcaaaaagtt ctcgcctttg cggataggac
      601 gaactgccct cggcgcacca ttgcataaat tttcttattt ccctgatttc aagtcccgat
      661 tttttgaggc agtcaattat gcggagtgtt tcaagctctc tgtcggaaaa tctgcggata
      721 cccgacaccc tctccatatg cggaaaaagt ccctctttgt cgtaataacg cagggttgaa
      781 acaggaatac cgcacatctg agatacctga ccgattgtgt acataaaatc actccaaaac
      841 attctaaaag gtcttgacct aaagccaagt ttatctgtca atacaatcat actgcataat
      901 gatttggttg tcaattgaat tgtttttaaa ataaaaaatt aacggagcag attttaattt
      961 ctgctccgtg tttgttagga aaatatgctt gccacattga ttccgtttgt ggttatgttt
     1021 aatattattc cgattacggt catcgggatg attatgactg aaagaaattt aaagaatgat
     1081 cccgcactgg aaaaaaattc agtgcctttg gtatagacaa aaggtgattt tacaaatttt
     1141 tcggctatgg gtgatttgga gatgtagtag aattgtcttg atactgtaat gccgaagtgg
     1201 gcgaacatta tactgttcca cacatttccc gccttgccga taaagcccat aaacggcata
     1261 caataaaaaa tgtataacgc aatgaacagc aatatcggtc tgagaaaagt tatttttgag
     1321 gtgggatagt tacatcccaa aacattaacc gtactgagca aaattaggac aaacaggatt
     1381 atcagaacaa taatgcctat tacattttcg tgtgtaatat taatgccgca attttggagt
     1441 atggcaattg tcaaaagcaa gatagctgcg atacccgtgt acacaaagtc aaaaatcatt
     1501 agttgctttt tcatataaat ctccgtgttt taaaatatat gctgaatata ccatgttttt
     1561 tgacattata caatactatt gttatttaat tggaataagt cacatattga acacttttta
     1621 cttgttgaaa ttgcatataa aaagaaagca aggcacgaaa ttgcaccttg ctttttggga
     1681 agatatatta atgtaacttg ttgttttgat tatttctttt cgagaacatt gaggaaatct
     1741 tcaatttcgg caagcttttc tttggcaaga tttttgccgg cgttatatgc ctcgtcaagc
     1801 acatccgtgt tcatctcaaa tgattttaca tacttgtgtg acgggcggag taccataagt
     1861 atgccgtcct cctcaagctg tttcattctt ttgcattgct cattatagcg gtcaaatctc
     1921 gtcataagag cgttgatgag gttcggatag tccttgtatt ttttgttgat taaaaattca
     1981 aacttgcgat agtccgtgca aggctcattt tcgggttttg tcaaaagcac aagcacacgg
     2041 gaacagccct gttcaaacgc acggtcaaag ggaacagcgt cggcaatact gccgtcaaca
     2101 tactttccgc cctcaaattc gcttatctga tagagaatag gaactgtgca ggacgctctt
     2161 acggagtcaa gcaatcgctg ttcgcttttg ttctcggaaa aatattttgc cttgcctgtt
     2221 acgcagtcgg ttgccacaaa ttcgcagttt gtatctgacg caaaaaatgt atcaaaatcg
     2281 aacggatagt cctgataagg aaatctgtaa atcatattgt caagatccat tgaaagaaaa
     2341 ccgagaaccg aaaaatcgcc tgttctgtgg ggcataataa ccctgcggga acgaccttcc
     2401 tgttttgcgg taaaatcaag ggcgacctca gctcccgccg aaactcctgc aacatagtca
     2461 aagtgtattt tgttttcaag cagacagtcg gttataccgg cggtaaaaat tcctcgcctt
     2521 gctccgcctt caattatcag acctgtcata aggacctccg ttgactcaaa aaaattttgg
     2581 tgctataatc aaactgtttt atggggtgat agtatggatg ctaatgtgac tgaccttcgc
     2641 attgtaaaaa caagaaccaa tataaaaaat tcgctgattg atttgcttgc cgaaaaaaat
     2701 gtttccaaaa tcacggtgac tgagcttgca gaaaaggcga tgattaaccg caaaaccttt
     2761 taccgccatt atcacacggt tcaggatgtt gtcgatgata tcaattacga tatagtcaac
     2821 gatgttatca gccatgcgaa aaaatccgac cgtgacggca acaatcttgt gaatcagctg
     2881 aattttatcg gtctttccat tgttgaaaat aaagaacaga ttaataaaat tctgaaaaat
     2941 tctcccgagg tgttcggctc gggacgctct gttgagcttt tgaaaagatt tatcgaggtt
     3001 tcaataagac ctgtgcttaa ttttaaaaat gaaacaaaac tcaaatacct tgttgagttt
     3061 gtcgtttcgg gattcatctc ggtttatgtc cgttggttca atgacggctg tgcagaaagc
     3121 tccgaaaagc ttgcagacgc tgtcaacgag tttgttctcg gagcattgtc cgaatatgtt
     3181 cgcccgaaaa gctgattaac tcattttcca atgagcctta gtaattgcct cgaatccttt
     3241 gggggagaga ataggctttg aaattttttt cattgtttcg tcgcaaagac agcggttttc
     3301 gcagaattcc ctgcctgcct ccgtgattga atcaaggtat gcctttctct gcctttcagc
     3361 tttttctgca ataaaaagct cgccctcggg gcattttatc atcgtgtaat tgccgttacc
     3421 gcaaatcaaa tcaagctgtt ttataagtgc gggatacatc ggttcggcac tcacatagcc
     3481 gcaagtcgta ataaccaaaa gcctcttttc gtgcattgct tcatcacgca gttcatggaa
     3541 agaggcttct ttgtcctcgg caacatttcc cgaatagggg agcatatacg gcagacatct
     3601 gtcggttaat gctttcatct gtgacggcat accgaaaaag tagagcggaa agctctcaat
     3661 gataatatcg gcagaattaa tcttttcgta gattttctgc atatcgtcct ttataacaca
     3721 tttgccgggt gttctgctcc aacacgaaaa gcaacccata cacggcttga ttgtttcctt
     3781 tttaaccgtg atatattcaa cttccgtatc ggctgaaaag ccgtcaagaa atgcttttgt
     3841 aatgttgaga gtattgcttt tttcgccctt tggactaccg tttaatacga gaactttcat
     3901 aatcactcct gtgacggctt gtaaaccgca tttttatcca ttgtggtaaa caaaagattt
     3961 ccctttgccc tcacttcacc gtcaaccttg atgacacacg caaattcaaa tgccgacttt
     4021 gttgacattg taacatttac gctgataata agcgtatcac ccggaataac ggggcggagc
     4081 attttgaaat ccttgacttt tagaagaaca tataacttgt cctcctcaac gctttcggga
     4141 gcaaatacaa gactgcaaag ctgtgccgca gattcaatga gcaatactcc cggcataatc
     4201 ggtgtgtcgg gaaaatgacc tgaaaaatac ggctcgttca ccgacacatt tttaatacct
     4261 gttgccgaaa cattcggctc aagctcggtt accctctcaa tcatctgaaa gggtggtctt
     4321 tgttttattc tttgattgat ttcaagcaga ttcatcataa gctgagtcct ccgtcaagca
     4381 caagcacctg acctgtcata tatgaaaaat cgtcactgca aagctgtccg acgacatttg
     4441 cgacatcctg aactgtgccg aatctctttt cgggaatagc ctcaagatac tttttctgca
     4501 attcttcagg aatgccgttc atcatttcgg tttcgataaa accgggtgca actgcgttta
     4561 ctctgattcc gtactttgca agttcctttg caagcgtgtg tgtcatagcg tttaccgcac
     4621 cctttgttgc actgtaaacc gactgacctt caactgcaag aacagagctt acggaagaaa
     4681 tgttgatgat gattccgctc tttttgcgga gcattttaag cgatgcctgt cttgcacaat
     4741 tgaaatatcc tttgatatta atgtcaagac ttctttcaag cgactcgtcc ttaatcatca
     4801 aaaggtaagc gtcgtcaacc acacctgcgt tgttgacaag cacatcaatt ccgccgaagt
     4861 cctgctgaat actgcggaac atatccttta cttcgtcaat atctgccgtg tttgccttgt
     4921 aggcaacggc ttttctgccg agtgatgtaa tttcgtcaac agccttttga gccatttcta
     4981 aatttgaatt gcagttcacg gcaatgtcat atccaagctc tgcaagcttt aaagcgcaag
     5041 ccttgccaat gccccttgat gaacctgtta caagagcggt tttgctcata tttacctccg
     5101 atttttacgc tttcctcagg attacagcag agtatgttcc gcccgcaccc attgaaagag
     5161 caagtccgta ttcgtaattt ttctcgctgt cagaaagaag ctcagccgca tatgccgctg
     5221 tcattgcact tgctgcggct cttgcattgc cgatttcctg cgatacatca tagcacggca
     5281 taagcgtctt gataatcttc ctgtcgtcac agcatacaaa gtcgatattg tctgcctcaa
     5341 tgccggcatt cacacaagcc ttttcgataa cctcaacaac agccttgctg tcaacctctg
     5401 agttgtcata cgatacaggg cggtgagcct gtgcatagcc cttaatttct gcatacttgc
     5461 gtgcatttct gccgtttgca ctttcttctg tttcaagaac gagagttaca gagccctcac
     5521 cgagcggttt ttcaagcaat tcggcctttg tatagagttc aaggtttgtc tttgtatttt
     5581 catcggtacc tgcggcaagc ataacgcttt cgttgccgtc tgcaagaata tcagcggcat
     5641 agcaaatact ctgcagtcct gcctgattgc cgtttgcaac agttgcgttg tagcccttga
     5701 tacctgagaa aatgctcaga taaccgcctg cggcattgta aaccgtattc gggaatgaaa
     5761 aagcactgcc cttttcggta cctcttgtga ttgccttttt ctggaaatca acaatttcgg
     5821 tcatagggcc gtcagccgtg ccgattacga tacctgtttt atattcgttg tccttgtcaa
     5881 tttttatgtc agcgtctgca agtgcgtcca taccgctcaa aagctggagc tggctgaaac
     5941 ggtcaagctt tctgtaaaat gcaaccttga ttccgtgttt gtcataatct tcggaggtaa
     6001 gattgcagtt aaggctgtgt tcgtcagtct ttgtgcctgt aagctttgaa atgcccgtaa
     6061 tgtaaatttt ttcattttta ctgttgtcgg gaatatcatg ctcgttgtcc gagaaaatga
     6121 tgcttgcgtt gttgccgccg aatgcaaatg agtttgacat tgcatagtga acatcttttg
     6181 tgtggctctt gttcggaata aagtcaatgt tgcccgcctt ttcggaaagc accttcaaat
     6241 cctcatcgga gtagccgatt gtaggcggaa cgaggttttc ttttattgct tttacggaaa
     6301 atacagcctc aattgagccg gccgcaccga ggcaatgacc tgtcatagat tttgttgagc
     6361 tgacagaaag gtggtcgttg ccgtcaaaaa gtgtgtgaag tgaaagaaat tcagcctcgt
     6421 catttttggc agtacccgtt ccgtgtgcgt ttatgtagtc gatatcgtca aaactaagag
     6481 cagagctttc aacagccctt ctgattgcac tcatctgacc ttcaccgtcg ggacggggag
     6541 cggtaatgtg gtaagcgtca ctgcttacac ccgaaccgag aatttcacag taaatctttg
     6601 cacctcgttc aacagcgtgt tcgtagcttt cgattacaag aatacccgaa ccctcgccga
     6661 gcgtgatacc tgtgctgtga ttgaacgggg aacaggcgtt ttcgtcaagc gcatggagag
     6721 cgtggaaacc gctgaatgca agtgaagaaa agctgtccga accgcctgcg atgaacacat
     6781 cacccttgcc ctcacggata aggtcacagg catagccgat gctcattgtg cctgccgcac
     6841 aagcgttgac gatgtttgcg gtaatgccct caagtccgaa atgagcggaa acattgttgg
     6901 caattgccga agcacccatt ttgaaaatat cttctttttt accgccgtca cccttgattt
     6961 cgtctgtgta atatttgtca atgcttgccg caccgcctac acaactgcca agaataacac
     7021 cgatgttttt ttcggatgcg tcaatgcttg catcttcaaa agcctcgttt gcggcatgaa
     7081 tacagagaag ggaagaacgg tcatagtttt cgggagaaag ctctgacgat gccttgtcaa
     7141 cctctgcacc tttgtgtgca taacagtttg aggtgtcaac cgacttaacc tcatcaatgc
     7201 cggagtgacc gagtgttacg gcatcccagc aatcctttac attgtcaccg acgccgcaga
     7261 taagtccgag tcctgtgaca acacatctct ttttgtcagc catattaacc ctgcttgctt
     7321 tctacatatt ctgtaagtgc tctgattgat tggaagtgct cacggtctgc acctgtcata
     7381 tcaataccga aaagtgtgtc gatgcctgca acgatttcga ttgagtcgat tgagtcaaga
     7441 ccgatttcgt caccgaaaag ttctgaatcg tatgtaagaa tgttttcggg aattctaagg
     7501 ttttctacga gcatttcctt aatctgatct gcaatagcat tgttcatttt aattacctca
     7561 cttaaaattt tgattttttt gattttatta taaattttcc gaagaaaaat cttctttgta
     7621 ataaaccttg cctttgccgt atttttcttc aagctcaaga taaagctttt tgacctgctt
     7681 ttcggcttcg gcacttattt cttttgcata ttttgagcag cgaacatttt cgggacattc
     7741 ggattttatc ggattgccga ttaaaatttt ctgcctcttt ccaaaaagaa ttttatactc
     7801 acccaaagat gcaatcggga ttatgtcaag accttttttt gccgcaagca atgccgcacc
     7861 gggcttgaac gggagcattt tgccctctct tgcaattccg ccctcgggga agataagcat
     7921 tgaatatccg ttttcaaccg caccctcact ttgcgcatac cagtttgtgt ccatggtgtc
     7981 aaagtcaacg ggaatactgc ggcaaattcg gataaacgag cctgttccgc tcttgtcgta
     8041 ccagcttttt ttaacaagca tatacggctt gtatctgctg agtacagagc ttatcacaac
     8101 tccgtcaaag tggtgagtgt ggttgcatac aaacacaaca ggcttgccct tgaggctctt
     8161 tttaaggctc ttgtccttcc attcaacctt agggcgaata agaagatgca caagaccttt
     8221 tacaaatttt atgaatgcaa gctgtcctgc atttttatga taattgtact ccatactctt
     8281 taccctcgtt ttttagaata ttatattttt attttaaaag aattcaacgg tcaaatgaat
     8341 tttgcgtgtg tcttatgcaa cattctgtcg aattttgtgg cataaaatat atgggaatta
     8401 ttatggaata tttttctttt tagctttttt acaaatgttg acggctgttg tttatggtga
     8461 tataatcata gaaaagaatt ttgcctttga atcaaggtaa acaaaggaga aacctatgaa
     8521 aaaagtaatt ttaacaggtg accgtcctac gggcagactt catgtcggtc actatgcagg
     8581 ttcgctcaag gagagagtaa agctccagaa ttcgggcgaa tatgatgata tataccttat
     8641 gattgcagac gctcaggctc ttaccgacaa tgccgagcat cccgaaaagg taagacagaa
     8701 tattttgcag gttgcgcttg actaccttgc ctgcggaata gatccgaaca agtcaacaat
     8761 ttttgttcag tcaatgattc ccgagcttac agagcttact ttctattata tgaacctcgt
     8821 aaccgtgtcc cgtgttcagc gtaaccccac cgttaaggca gaaattcaga tgcgtaattt
     8881 tgaggcaagc attcctgtgg gatttttctg ttatccaatc agtcaggcgg ctgatatcac
     8941 ggcattccgt gcaactgccg ttcctgtcgg cgaggatcag cttccgatgc ttgaacaatg
     9001 caaagagatt gttcacaagt tcaattccgt ttacggcgaa actcttacgg aaccgcagat
     9061 tattcttccg agcaacaagg cttgtctgcg actgcccggt attgacggca aggcaaagat
     9121 gagcaaatcc ctcggcaact gcatttatct tgcagaagaa cccgaggata tcaagaaaaa
     9181 ggttatgtca atgtttaccg acccgaatca tcttcgtgtt gaggatcccg gcaaggttga
     9241 gggcaacccc gtatttatct atcttgacgc attctgccgt gatgagtatt ttgcggaatt
     9301 ttggaatgat tacagctgtc ttgacgaact caaggctcat tatcagcgtg gcggactcgg
     9361 tgatgtcaag gttaagaaat tccttaacaa tgttatgcag gaggagcttc gtcctattcg
     9421 tgaacgcaga aaagaatggg aaaatcatct tcccgatgtt ctcaatattc tcaaagaggg
     9481 cagtaaagtt gcaaaggaaa ctgccgcaaa aacacttgag gatgtccgtc attctatgag
     9541 aatcgattat tttacagaca ataatcttct taaataattt aaaattcaat atgtaaaata
     9601 aaggtcggaa ggacagaaat caaaaattct gtctttccga tttttcttat gaaaaaatta
     9661 ttgcgaatcg actcaaaatt gttgaaaaaa taataatatt atgctattat tgcgttgaaa
     9721 acaccccgtt ttaaggagaa tacattatga ttgacgcaag aaagcatacg cttgattctg
     9781 ttaaaaagct gaccgattac agcgatttta acctttataa aatggatata tgctacgatt
     9841 acagcattga taaaatcatt gacagaggga tttttgatga tgagtcggct ctcggtgcaa
     9901 ttttgcagga ggttctgccc gattatcccg tcaatcttaa aatgccgaat ttcgggtgca
     9961 gtgcctttac aatgaaaaat cccgacagcg taatgatggg gcgaaactat gattttaaga
    10021 acgacacctc gtcaatgctt gtgtattgtt cgccaaagaa cggctacagg tcggttgcgt
    10081 ttgcggcact tgataatgta ggtgcaaaca accccgagtt gagtgatgaa acaaggcttg
    10141 caaccttgct ctcaccgttt atcagccttg acggaatcaa tgaaaagggc gtgtcaatcg
    10201 cagttctcac acttgacagc aagcccgtcc gtcagcaaag cggaaagcct gttattgcca
    10261 caacgcttgc aatccgtctt atacttgaca gagctgcgtc aaccgaagag gcggttacac
    10321 tttttgaaaa atacgatatg ttcgcctcaa gcggaagaga tt
//
