LOCUS       c00076_gnlPro..        11294 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KJHFNGNC_76.
ACCESSION   c00076_gnlPro..
VERSION     c00076_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 21:10:50
            Original ID  :: gnl|Prokka|KJHFNGNC_76
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11294
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11294
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6674:9618]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      6675..9618
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..11294
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..11294
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             133..981
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP_bind_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg76_1"
                     /sec_met_domain="ATP_bind_3 (E-value: 6e-08, bitscore:
                     21.6, seeds: 28, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLEHLKEYLKGLGSVAVAFSSGVDSTFLLKVAHDVLGDKAIA
                     ITAQSCSFPKRELNEAKAFCEKEGIQHVICQSEELEIEGFSKNPPNRCYLCKKELFEKI
                     GDIAKKNGIEYIAEGSNMDDNGDYRPGLIAVKELGVKSPLREAKLTKAEIREYSKELGL
                     PTWDKQSFACLSSRFVYGETISEEKLGMVEKAEQLLLDYGFHQVRVRIHGSLARIEIMP
                     EEFPKLLEKNVREDIAKKFKEYGFTYVTMDILGYRMGSMNETLGENDKTTADSSLKGKN
                     E"
     CDS             978..2765
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M24"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg76_2"
                     /sec_met_domain="Peptidase_M24 (E-value: 2.5e-43, bitscore:
                     137.1, seeds: 437, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVKERIAALRARMKETGIDAYLIPTDDFHGSEYVGEYFKCRKYI
                     TGFTGSAGTAVIMQDMAGLWTDGRYFIQAADQLEGTGITLFKMGEPEVPTVHEFLKKNL
                     TQGRCLGFDGRTVSAKEAAELEKMLDENGVSLSVDHDLAGDIWENRPVLSCEPVTELDI
                     KWAGESRADKCARIRKAMEKKGADLFVLTSLDDIAWLLNIRGGDIHCCPVVLSYLVMTK
                     TEIRLFANEKAFQTDVLEALEKDGVTLFPYDSIYEYVKTFKKDKKVLLCKKKVNSRLVS
                     NIPADTRILDEENLTLLPKATKNPVEVENERIAHIRDGVAVTKFIYWLKKNVGRIPITE
                     LSAAEKLYEFRSEQEDFIDNSFDPIIAYGKHAAIVHYFATPETDIPLEPSGFLLADTGG
                     HYKEGTTDITRTVVMGPTTEEEKKYFTAVLRGTLNLGAARFLHGCTGVNLDILARQPLW
                     EMGEDFKHGTGHGVGYLLNVHEGPNSFRWKIVPGGNAVLEEGMITSDEPGYYREDEFGI
                     RHENLMVCKKAEKTEYGQFMCFEFLTMVPFDLDGVVSELMSVRERNLLNDYHAQVYEKI
                     SPYLNEEEKEWLKDATRAI"
     CDS             complement(2853..4619)
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     286.7; E-value: 2.2e-87)"
                     /gene_kind="resistance"
                     /locus_tag="ctg76_3"
                     /transl_table=11
                     /translation="MSRSTIKDPAKSKSSETFFKVLRFIGRYRFLLIFSIILAAVSVIL
                     QLYVPILFGNAIDQVIAQHQVNFEMMWYYLSRILVMVILSSAATWLMNVINNRMTYQTV
                     KDIRAKAIRHIQVLPLSYLDGHSTGDIISRIIADTDILSDGMLLGFTQLFSGIVTIIGT
                     LIFMFSKNFWITLMVIVLTPVSFLVAKFISSHTFQMFRKQSDARGRQTALIEEMIGNQK
                     VVQAFGYEEKSSERFAKVNEELQECSLKAVFYSSLTNPSTRFVNNVIYACVALVGAFII
                     PGGRLTVGGLSVLLSYANQYMKPFNDISSVVTELQNALACAGRIFDLLEEEPEVAEASE
                     TLKDVKGEVDIKNVCFHYDESKKLIEDFNLHVKPGMRVAIVGPTGCGKSTFINLLMRFY
                     DVNSGSISVDGKPIRDITRHSLRSSYGMVLQETWIKNGTVRDNISIGKPEATDTEIIEA
                     AKLTHSWEFIRRLPKGLDTMLNEDSLSQGQKQLLCITRVMLCLPPMLILDEATSSIDTR
                     TELQIQEAFERMMEGRTSFIVAHRLSTIRNADLILVMKDGSIIEQGTHDELIAKGGFYH
                     TLYNSQFAKVSE"
     CDS             complement(4616..6430)
                     /locus_tag="ctg76_4"
                     /transl_table=11
                     /translation="MRSLTVYLKNYKKESILAPFFKFLEVVFDLIVPIVIAQIIDVGIA
                     NHDNKYIVQRFSILILMAALGLASTITAQFFAAKASVGFATELRQAVYDHVQHLSFTEL
                     DTLGTDTLITRLTDDINQVQNGLNMGLRLLLRSPFIVLGSMVMAFTIDFKCALVFAVAI
                     PFLFLVVFVIMFFSIPLFKKVQGKLDTVTGLTRENLTGVRVIRAFCREKEAVAEFDTRN
                     QELTKLNLFVGKLSALLNPVTYVLINIATVILIQKAGVEVNLGGMQQGQVVALYNYMAQ
                     MIVELIKLASLIITLNKSAASAGRVADILKVKSTMDYPSSSTYSAQISKDLATATADAS
                     LSENAIVFNDVTFEYSKAGAPSLSHISFSVKKGQTVGIIGGTGSGKTTLVNLISRFYDA
                     SKGTVLLDGQNIENYTRSDLRSRIGVVPQKAALFKGSIRDNLKWGREDASDEDLWQALT
                     TAQGKEVVEGKPGQLDFMLEQNGKNLSGGQKQRLTIARALVKKPEILILDDSASALDFA
                     TDAALRKSLNRLDWKVTTFLVSQRSSSIQQADLILVLDNGTLAGKGTHAELLRTCDTYR
                     EIYFSQFPEERARYSSVSAGNIMKEVTV"
     CDS             6675..7946
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg76_5"
                     /sec_met_domain="HGD-D (E-value: 1.6e-56, bitscore: 181.2,
                     seeds: 370, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIIETFGHYVENLTDKKPQSARRLLKTGWEAQNLKFRYMQDKRL
                     MPADRHLANLMMDTMLWPLQKPEDSVIVSIFTPCEMMQEVGLHPYNVEGFSCYLSASKA
                     ERAFLQQAENQGIAETLCSYHKTFLGAAQKGLLPKPKCIVYTNLTCDANLLTFRTLADF
                     YQVPVFAIDVPWNQTTENVQYVADQLKDLKIFLEKNTGKTISEDRLKERLACSKRTLEN
                     YKKYQQMRADRYVPSDLVTPLYAGMTNNILLGTAEEEKYTQMLLEDIKKAPAAKGKHIY
                     WMHTIPFWSDAVRQELCFSEKAQIVGCELAETCEPDFDPENPFEAMAERMVYHSLNGSA
                     LRRIEAGIRHAKQAGADGAVWFGHWGCKHTLGAAQLAKKKFEEAGLPLLILDGDGCDRS
                     HGGEGQTSTRLGAFLEMLGGAENE"
     CDS             7939..9618
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg76_6"
                     /sec_met_domain="HGD-D (E-value: 9.4e-18, bitscore: 53.8,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 6.5e-66, bitscore:
                     211.4, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTYYVCKYTPIELLESLGGECENFNHMPEGFDLADQVSHPNIC
                     GFGKTLLEGVMEGKIKELVLVSCCDTIRSVYDILLESGKLDFLYILDVLHCDSACSRER
                     MAVQLKGLAKAYAQYKGTEFDAGKFRAAFHAQEKITKSHIAVLGARMGQELFEMTSKAM
                     PLPVENDTCVHNRSVGNILPPEGASFDELMDWYAGEILGQIPCMRMMDPTGRKKLYNDP
                     SVAGIIYHTVKFCDFYSFEYAEIKNHTDVPLLKIESDYTIQSSGQLLTRLEAFAESIQP
                     ETLEQTIDGDTKGERKMGKGYFAGIDSGSTSTDVVILNKDHEIVTSIILPTGAGAAIGA
                     DRALAEALKEAGLQREDIDALVTTGYGRTAIKNGDKSITEITCHARGAHFLNPEVRTVI
                     DIGGQDSKVIRLDENGAVANFVMNDKCAAGTGRFLEMMARTMEMNLDQMSECGLEFKED
                     ITISSMCTVFAESEVVSLIAQNKATDDIVHGLNKAVAVKTAALTRRVGGEEKYMMTGGV
                     SKNKGLVKTLEEKLGTKLVISDKAQLCGALGAALFAADMADV"
     CDS             10122..11294
                     /locus_tag="ctg76_7"
                     /transl_table=11
                     /translation="MWEAINSFLTTVDNLVWGVPLMVLIMAGGILLTARLGLLQMRRLP
                     LALKWMFKNEEEGDGEISSFAALCTALSATIGTGNIVGVATAVCAGGPGALFWMILAAF
                     FGMATKFSEGLLAVKYRVVAEDGHSLGGPFYYIEKGMGTKWKWLAKIFAFFGVCVGLFG
                     IGTFSQVNGISSAVQNFFDPNKSNCVNIPFLGEYSWAVVISSLILAACVAAILIGGLKR
                     IATVSQIIVPFMAVIYLIFSVALILLNITEIPAAIVTVVKGAFNPSAVTGGVVGTMIVS
                     MQKGVARGIFSNEAGLGSAPIAAAAAQTKEPVRQGLVSMTGTFIDTIVICTMTGLSIVL
                     TGAWQVEGLEGVQVTTYAFQHGLPIPGQISAFVLMICLVFFAFTTILGWDY"
ORIGIN
        1 gaagctatag caccctgtta aataatacat ttgagaaagt tcaactttca cgctttgttg
       61 agccagatca atatacatta tttacgagga gtgctacagg tacaataaaa aacggacaag
      121 aggcagactg atatggaaaa taaactggaa catttaaaag aatatctgaa gggacttggc
      181 agtgtagcag ttgctttctc aagtggagtg gattctacat tcttattaaa agtagctcat
      241 gatgtgctgg gtgataaggc gattgcgatt acggctcaat cctgttcttt cccgaaaaga
      301 gagctgaatg aagcgaaggc attctgcgag aaagagggga ttcagcatgt gatctgccag
      361 tctgaggaat tggagattga aggattttca aagaatcctc cgaacagatg ttatttatgt
      421 aaaaaagaac tgtttgagaa gattggcgat attgcaaaaa agaatgggat tgaatatatt
      481 gcagagggat caaatatgga tgataacggc gattacagac caggtctgat cgccgtaaaa
      541 gaacttggag ttaagagccc gctacgtgag gcgaagctga cgaaagcgga gatcagagaa
      601 tactcaaagg aactggggct tccgacttgg gacaaacagt catttgcctg tctgtcctcc
      661 aggtttgtct atggagagac catcagtgag gaaaagcttg gaatggttga gaaagcagag
      721 cagcttttac ttgactatgg attccatcag gtacgtgtcc gtattcacgg ttcacttgca
      781 agaattgaga tcatgccgga ggaatttccg aaacttctgg aaaaaaatgt ccgagaggat
      841 attgcaaaga aatttaagga gtatggattc acttatgtga ccatggatat tctgggatat
      901 cgtatgggaa gtatgaacga aacacttggc gaaaatgata aaacgactgc agatagcagc
      961 cttaagggta aaaacgaatg acagtaaaag agagaatagc agcacttcgt gcacgcatga
     1021 aagagacagg aattgatgca tatctgattc ctacagatga ttttcatggt tcagaatatg
     1081 taggtgaata tttcaaatgc agaaaatata tcacaggatt taccggttct gcaggcactg
     1141 cggtgatcat gcaggatatg gcaggattat ggacggatgg acgttatttt atccaggctg
     1201 cagatcagct ggagggaaca ggaattactt tatttaaaat gggtgaaccg gaagttccca
     1261 cagttcatga atttctgaaa aaaaatctga cacagggaag gtgtctggga tttgacggac
     1321 gtactgtcag tgcaaaagag gcagcagaat tggagaaaat gctggatgaa aacggtgtgt
     1381 ctctcagtgt tgatcacgat ctggcaggcg atatatggga aaaccgtccg gtactttcct
     1441 gtgaaccggt tacagagctg gatataaaat gggcaggaga atccagagct gataaatgcg
     1501 caagaatccg caaagcaatg gagaagaagg gtgcagattt atttgtactg acttctctgg
     1561 atgatattgc ctggctgtta aatatacgtg ggggagatat ccactgttgt ccggtggttc
     1621 tttcttatct tgtaatgaca aaaacagaga tcagactttt tgcaaatgag aaagcctttc
     1681 agacagacgt actggaagcg ctggaaaaag atggtgtgac cctttttccc tatgacagta
     1741 tctatgagta tgtgaaaaca tttaaaaagg acaaaaaagt tcttctctgc aaaaagaaag
     1801 tcaacagtcg tctggttagc aatattccgg cagacacccg gattctggat gaagaaaatc
     1861 ttacacttct tcccaaggca acgaagaatc ctgttgaggt ggaaaatgaa cgcattgcgc
     1921 atatcagaga cggagttgca gttacaaagt tcatatactg gttaaagaag aatgttggaa
     1981 ggattccaat cacagaatta agtgcagcag aaaagctgta tgaattccgt tcggaacagg
     2041 aggatttcat agataacagt tttgatccga ttattgccta tggaaagcat gctgctattg
     2101 tacattattt tgcaacaccc gaaacggata ttcctctgga accatccggc tttcttctgg
     2161 cagatacagg aggacattat aaagagggaa ctactgatat tacccgtact gttgtcatgg
     2221 ggccgactac tgaggaagag aaaaagtact tcacagcagt tttgcgggga actctgaatc
     2281 tgggagctgc cagatttctt catggctgta ccggtgtaaa cctggatatt ctggcgagac
     2341 agccgttgtg ggaaatggga gaggatttta aacatggaac cggtcatgga gtaggatatc
     2401 ttctgaatgt ccatgaagga cccaatagct tccgatggaa aattgttccg ggtggaaatg
     2461 cagtgctgga ggagggaatg atcacctctg atgagccggg atattacaga gaggatgaat
     2521 ttggaatccg tcatgaaaat ctgatggtct gtaaaaaagc tgaaaaaaca gagtatggtc
     2581 agtttatgtg ctttgaattt ctgactatgg taccttttga cctggatgga gtggtgtcgg
     2641 aactgatgag tgtccgggaa cgtaaccttc tcaatgatta ccatgcgcag gtatatgaga
     2701 agatttctcc gtatttgaac gaagaagaaa aagaatggct gaaagatgct acccgggcaa
     2761 tctgataaaa ataaaaaaac attttacaaa atcaaaaaga ggaacagccg tgatggacag
     2821 ctgttccttt ttgatttatt atctggcttg ttttattcag aaacttttgc aaactggctg
     2881 ttatataaag tatggtaaaa tccacctttt gcaatcagct catcatgagt accctgctca
     2941 atgatacttc cgtctttcat aacaagaatc agatctgcat ttcggatggt tgaaagcctg
     3001 tgagctacga taaagcttgt tcttccctcc atcattcgtt caaacgcttc ctgaatttgt
     3061 aattctgttc gtgtatcaat actggaagtg gcttcatcca ggatcagcat cggaggcaga
     3121 cagagcataa ctcgtgtgat acacagcagc tgtttctgtc cctggcttaa gctgtcttcg
     3181 ttgagcatgg tgtccagtcc tttaggaagc ctccggataa attcccagct gtgggtaagc
     3241 ttggctgctt cgatgatttc agtatctgta gcttccggtt ttccaatcga gatattgtcg
     3301 cggacagttc cgtttttgat ccatgtttcc tgaagcacca taccatagct gcttctgaga
     3361 gaatggcggg taatgtctct gatcggtttg ccgtcaacgg aaatagatcc ggaatttaca
     3421 tcatagaatc tcatcagaag gttgataaag gttgacttac cgcatccggt aggtcctaca
     3481 atggcaacgc gcatacctgg ttttacatgg agattaaagt cctcaatcag tttctttgat
     3541 tcatcataat ggaagcacac attcttaata tctacttcac cctttacatc tttcagtgtc
     3601 tcagaagcct ctgcaacttc cggttcctcc tccagcagat cgaagattct gcctgcacag
     3661 gcaagagcat tctgaagttc tgtaacaacg gaactgatat cattgaatgg tttcatatac
     3721 tggttggcat aggagagaag tacggaaagt cctccgactg tcagtctgcc tccagggata
     3781 atgaatgcac ccaccagtgc aacacaggca taaataacat tattgacaaa acgggtggaa
     3841 gggtttgtca ggctgctgta aaaaacagcc ttcagactgc attcctgtaa ttcttcgtta
     3901 acctttgcaa aacgttcaga agatttttcc tcatatccaa aagcctgaac aaccttctgg
     3961 tttccaatca tctcttcgat gagagcagtc tgacgtcctc tggcatcgct ttgcttccgg
     4021 aacatctgga aggtatggga agaaataaat ttggccacca aaaagcttac gggggtcagg
     4081 acaatgacca tcaatgtaat ccagaagttt ttggagaaca tgaagatcag tgttccgatg
     4141 atcgttacga ttccggaaaa aagctgggta aatccaagca gcataccatc ggatagaata
     4201 tctgtatctg cgataatacg gctgatgata tctccggtac tgtgtccgtc aaggtaagag
     4261 aggggaagta cctgaatgtg tcggatggct ttggcacgta tatcctttac tgtctggtag
     4321 gtcatgcggt tattgatcac attcataagc cacgtggcag cagaagagag gatgaccatt
     4381 acaaggatac gtgacaggta ataccacatc atttcgaagt ttacctgatg ttgggcaatg
     4441 acctgatcaa tggcatttcc gaacaggatt gggacataca gctgaaggat aacggaaact
     4501 gctgccagta tgatactgaa gatcagcaga aaacggtatc ttccgatgaa acgcagtact
     4561 ttaaaaaaag tttcgctgct tttgctttta gcaggatctt ttattgttga tctgctcata
     4621 cagtcacctc cttcattata ttacctgcag atacagagga gtatctggct ctttcttccg
     4681 gaaactgaga gaagtagatt tcccggtaag tatcacaggt acgcagcagt tcagcatgag
     4741 tacccttacc tgccagagta ccgttatcaa ggacaaggat caagtctgcc tgctgaatgc
     4801 tggaggaacg ctgggatacc agaaatgtag ttactttcca gtcaagtctg ttgagagact
     4861 tacgcagtgc tgcatcagtg gcaaagtcca gggcactggc actgtcatcc agaatcagga
     4921 tttcaggttt ttttaccagg gcacgggcaa tggtaagtct ttgtttctgg ccgccggaaa
     4981 ggtttttacc gttctgttcc agcataaaat caagctgtcc cggtttaccc tctactacct
     5041 cttttccctg tgctgtggta agtgcctgcc atagatcctc gtcagaggca tcttcccggc
     5101 cccatttcag attgtcccgg atagagcctt tgaaaagagc tgccttctgt ggaacaacgc
     5161 cgattctgga gcggagatca cttctggtgt aattttcaat attctgacca tccagcagaa
     5221 cagttccttt gctggcatca tagaatctgg agatcagatt taccagagtg gtttttccgc
     5281 ttcctgtacc accgataata cctacggtct gtcccttttt tacagaaaaa ctgatatggg
     5341 aaagactggg ggcaccggct ttgctgtact caaaggttac gtcattgaat acgatggcat
     5401 tttcagaaag tgatgcatca gcagttgctg ttgcaaggtc cttcgatatc tgagcagaat
     5461 atgtggagga agaggggtaa tccatagtag atttcacttt caggatatct gccacacgtc
     5521 ctgcgctggc tgcagatttg ttcagggtga tgatcaggga ggcaagcttg atcagttcca
     5581 cgatcatctg agccatatag ttataaaggg caacaacctg tccctgctgc ataccgccaa
     5641 gatttacttc tactcctgct ttctggatca gaataacagt agcaatattg atcagtacgt
     5701 aagtgaccgg atttaacaaa gcggaaagct ttcctacaaa gagatttaac tttgtcagct
     5761 cctgattgcg ggtatcaaat tctgcaactg cctctttttc gcggcagaat gcacggataa
     5821 cgcggacgcc tgtaaggttt tctctggtca gtccggttac tgtgtccagt tttccctgta
     5881 cctttttaaa cagaggaata ctgaaaaaca taatgacaaa gacaaccaga aacagaaacg
     5941 ggatcgcaac agcaaaaacc agagcacatt taaaatcaat ggtaaatgcc atgaccatgg
     6001 atccaagtac gataaacgga cttcgaagaa gaagacgaag ccccatgttc agtccgttct
     6061 ggacctgatt gatatcgtcg gtaagtcttg tgatcagggt gtctgttccc agggtatcca
     6121 gctctgtaaa agacagatgc tgtacatggt cataaactgc ctgtcttaat tctgtggcaa
     6181 agcccacgct ggctttagcg gcaaagaact gagctgtgat ggtactggca agaccaagag
     6241 ccgccattag tataagaata gaaaatctct ggacaatgta tttgttgtca tggtttgcaa
     6301 tacctacatc aatgatctgt gcaatgacga taggcacgat caggtcaaat acaacctcca
     6361 gaaatttaaa aaatggcgcc aggatgcttt cttttttgta gttttttaaa taaaccgtca
     6421 atgaacgcat tttaaaaatt ccttcctttc gtaaaaaatc tttcctatat tatttcttcc
     6481 tttttttgaa aaataataca ttcaaaagtg tatcatttga gacttttttg tcaagaagaa
     6541 tgtgcaaaaa cagatgaact ttggagaaaa ttcagcttga cttcaaaaaa agatattatt
     6601 aaaatattcc gtggcactat ttgtgcactg acaattgata aattattatt accataatga
     6661 ggaagagaca gactatggag attattgaga catttggtca ttatgtggaa aatctgacgg
     6721 ataaaaagcc tcagtcagcc cgccggctgt taaaaaccgg ctgggaggcg cagaatctga
     6781 agttccgtta catgcaggac aagagactga tgcctgcaga caggcatctt gcaaacctga
     6841 tgatggatac catgctgtgg ccccttcaga aaccggaaga ttctgttatt gtaagtattt
     6901 ttacaccctg cgaaatgatg caggaggtgg gattacatcc ctataatgta gaaggatttt
     6961 cctgctatct ttctgcaagc aaagcagaga gggcattttt gcagcaggca gagaatcagg
     7021 gaattgcaga gacactgtgc agttatcaca agacatttct tggtgcagcg cagaaaggac
     7081 ttctgccaaa gcctaaatgt attgtttata ccaacctgac ctgcgatgct aacctgctca
     7141 ccttccgtac cctggcagat ttttaccagg tacctgtatt tgccattgat gtaccatgga
     7201 atcagaccac agagaatgta cagtatgtgg cagatcagtt aaaggattta aaaatatttc
     7261 tggaaaaaaa tacaggaaaa acaatctctg aggacagatt aaaggaacgt cttgcctgca
     7321 gtaagcggac tctggagaat tacaaaaaat atcagcagat gcgtgcagac agatatgtgc
     7381 cctctgatct ggtcacaccc ttgtatgcag gaatgacaaa caatatcctt ctgggaacag
     7441 cagaagaaga gaagtataca cagatgcttc ttgaagatat taagaaagca ccggcagcga
     7501 aagggaagca catttactgg atgcatacca ttccattctg gtcggatgca gtgcgccagg
     7561 agctttgctt cagtgagaaa gcccagatcg taggatgtga acttgcagaa acctgtgagc
     7621 cggattttga tcctgagaac ccctttgaag caatggcaga aagaatggta tatcattcac
     7681 tgaacggaag tgcccttaga aggattgaag ccggtatccg ccatgcgaaa caggcaggag
     7741 cagacggtgc tgtgtggttt ggacattggg gatgtaaaca tacgcttggt gcggcacagc
     7801 ttgcaaagaa gaagttcgag gaagccggtc tgcccctttt gatcctggac ggtgacgggt
     7861 gtgatcgaag ccatggagga gaaggacaga cttccaccag gctgggagct tttctggaaa
     7921 tgctgggagg tgctgagaat gaataaaact tactatgtct gtaaatatac cccaattgaa
     7981 cttctggaat ctcttggcgg ggaatgtgag aactttaatc atatgccgga gggatttgac
     8041 ctggccgatc aggtttcaca tcccaatatc tgcggttttg gaaaaacact tctggaagga
     8101 gtcatggagg ggaaaatcaa ggaacttgtc ctggtgagct gctgtgatac tatccggagt
     8161 gtctatgaca ttctgcttga aagcggcaag ctggattttc tctatatttt ggatgtgctt
     8221 cactgtgaca gtgcctgtag cagagagcgt atggctgtac agttaaaagg gctggcgaag
     8281 gcttatgcac agtacaaagg cacagagttt gatgccggaa aattccgggc tgctttccat
     8341 gcacaggaga aaatcacaaa gtcccatatt gcagtgcttg gcgccagaat ggggcaggaa
     8401 ttatttgaaa tgaccagcaa agctatgcct cttcctgtag agaatgatac ctgcgtgcat
     8461 aaccgttctg tgggaaatat acttccaccg gagggtgctt cttttgatga gctgatggac
     8521 tggtatgcag gtgagattct ggggcagatt ccatgtatgc gtatgatgga cccgacaggt
     8581 cgtaagaagc tttataatga tccgtctgtt gcggggatta tttatcatac agtgaagttt
     8641 tgtgattttt acagcttcga atatgctgag atcaagaatc atacagatgt acctctttta
     8701 aaaatcgaat cagattatac tattcagagc agcggtcagc ttcttaccag actggaagct
     8761 tttgcagaga gcattcagcc tgaaacactg gagcagacca tagatggaga cacaaaagga
     8821 gagagaaaaa tgggaaaagg ttatttcgca gggattgaca gtggttctac cagtacagat
     8881 gtggtgattt taaataaaga tcatgagatt gtgaccagca ttatcttgcc tacaggagca
     8941 ggagctgcta tcggagcaga ccgtgccctt gcagaggcat tgaaggaggc cggattgcag
     9001 agagaagata ttgatgcgct ggttactact ggatacggac gtacagctat taaaaatggt
     9061 gataagagta tcacagagat cacctgtcat gcaagaggtg cgcatttcct gaatccggaa
     9121 gtccgtactg ttattgatat tggcggacag gacagcaagg tgatccgact ggatgagaac
     9181 ggtgcagttg caaattttgt tatgaatgac aaatgtgcgg caggaaccgg acgatttctg
     9241 gaaatgatgg cacgtaccat ggaaatgaat ctggatcaga tgagcgaatg tgggctggaa
     9301 ttcaaagaag atattacaat ttccagtatg tgtacagtat ttgcagaatc agaagttgta
     9361 tccctgatcg cccagaataa ggcaacagat gatattgtcc atggcctgaa taaggcggtt
     9421 gccgtaaaga ctgccgccct taccagacgt gtgggcggtg aggagaaata tatgatgacc
     9481 ggtggtgttt ctaagaataa gggcctggta aagacactgg aagagaagct tggaacaaag
     9541 ctggtgatca gtgacaaggc tcagctttgc ggtgcacttg gcgcagcact gtttgcggct
     9601 gatatggctg atgtataaaa attatttaaa tatccaggga ttttacaagg tggaaatctc
     9661 tggaattttt atactttttt tataaaagtt taattttcta ttgacgagtt caaatttaag
     9721 agctatagta taccacagta acagcaaatt aacgaggtga agtttgcagg aaagaggaag
     9781 ccacacaaaa ggctataccc gccgaaggag taaaactctc aggttccctg gatgcaggga
     9841 agaactgcaa atggatcgtt tctctggaga cacccgttag atcgggggcc gaaggtgcaa
     9901 ataacacgaa ttatcaatag ctgcccacaa atggttatct gattcgtgtc ttgaatctct
     9961 caggcaaaag gacagaggat gctttatcat ccccgctgat tcatatgaac tatatgaaca
    10021 gtattttctg aacttctgat ttttgaaacg gtctgttatt actttgtttc ccagctgtac
    10081 aatatattac actttttaaa agaaaaagga gatttattat tatgtgggaa gcgatcaatt
    10141 cttttttgac aacagtagac aatctggtct ggggcgtgcc ccttatggtc ctgatcatgg
    10201 caggtggtat cctgttaact gccagacttg gacttcttca gatgcgaaga ctccctcttg
    10261 cattgaaatg gatgtttaag aacgaagaag aaggcgatgg tgagatttcc agctttgcag
    10321 ctttatgtac agcactgagc gccacaatcg gaaccggtaa tatcgtcggt gttgcaactg
    10381 ctgtctgtgc cggaggtccc ggagctttat tctggatgat tcttgcagca ttcttcggaa
    10441 tggcaacaaa attttccgaa ggtcttcttg cagtgaaata ccgtgtggta gcagaagacg
    10501 gtcacagcct tggtggtcct ttctattata ttgagaaagg tatgggaaca aaatggaaat
    10561 ggcttgcaaa gatctttgca ttctttggtg tatgtgtagg tcttttcgga atcggtacat
    10621 tcagccaggt aaatggtatt tccagtgcag ttcagaactt ctttgatccg aacaaatcaa
    10681 actgcgtaaa tattccgttc cttggagagt attcctgggc agttgtaatt tcttccctga
    10741 ttcttgcagc ctgtgttgca gcaatcctca tcggtggtct gaaacgaatt gcaacagtca
    10801 gccagattat tgtaccgttt atggcggtga tctatctgat cttcagtgta gcgctgattc
    10861 ttttaaacat tacagagatc ccggcagcta tcgtaacagt tgtgaaggga gcctttaatc
    10921 cgtcagcagt gacaggcggt gtggtaggaa caatgatcgt atccatgcag aaaggtgtgg
    10981 ctcgtggtat cttttcaaat gaagcaggtc ttggtagcgc acctatcgca gcggcagcag
    11041 ctcagacaaa agagcctgta cgtcagggtc ttgtaagcat gactggtaca tttattgata
    11101 caatcgtgat ctgtacaatg acaggccttt ccatcgtgct gacaggtgca tggcaggtag
    11161 aaggtctgga aggtgttcag gtaacaacct atgcattcca gcatggactt ccgatccctg
    11221 gacagatttc tgcatttgta ttaatgatct gtctggtatt ctttgcattt actacaattc
    11281 ttggatggga ttat
//
