LOCUS       c00118_gnlPro..         8359 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KJHFNGNC_118.
ACCESSION   c00118_gnlPro..
VERSION     c00118_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 21:10:50
            Original ID  :: gnl|Prokka|KJHFNGNC_118
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8359
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..8359
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[511:5860]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      512..5860
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..8359
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..8359
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             512..1948
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Vparvula"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg118_1"
                     /sec_met_domain="CT_Vparvula (E-value: 7.4e-137, bitscore:
                     445.7, seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNATQSLAGTRITSLLDANSFVEIGQGVTARSTDFNMTANKAPS
                     DGVITGYGVIDDKLVYVYSQDASVLNGTVGEMHAKKITRLYDLAMKTGAPVIGLVDCAG
                     IRLQEATDALEAFGQIYLKQTLASGVIPQITAIFGTCGGGMAVIPSLTDFTFMESKKGK
                     MFVNTPNALEGNNTDKCDTAAADFQSKETGVIDGVGTEDEILGQIRSLVSLLPSNNEDT
                     DNYTECTDDLNRVCADLANCAGDTAIALSQIADNGEFFETKADYAKDMVTGFIRLNGAT
                     VGAVANRSEVYDAEGKKTETFDGSISARGARKAADFVKFCDAFDIPVLTLTNATGFMAT
                     LCSEKMMAKSVGELVAAFADATVPKVNVIIGKAYGTAYVAMNSKSIGADLVYAWDNAEI
                     GMMDASLAAKIMYADADAAELNEKAAQYRELQNGVASAAARGYVDTVISPADTRKYVIG
                     AFEMLFTKREDRPSKKHGTV"
     CDS             1963..2718
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg118_2"
                     /sec_met_domain="OAD_gamma (E-value: 4.9e-28, bitscore:
                     86.6, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKMIKKITSVFMTFLVMAALVIGSTSVVFAADKVDDTVKSTLVTT
                     AEGLTDAIVQLKDEEIENYMSSGDDFTTSAMQSWQTSKDELGAKKDSNGETTVTFKDDQ
                     YTVTVPLKFEKAEANFVYVFDSQGTPTSMSVDVQYGMGKTLQRAGLNTLMGIGTVFVML
                     ILLSLLISLFRFIPNPEAKKAAEAKAAKAAKEAEAAAIAQTAPAQAEENLADDGELVAV
                     IAAAIAAAEGTTTDGFVVRSIRKVKRNRR"
     CDS             2746..3114
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 63.1; E-value:
                     5.3e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg118_3"
                     /sec_met_domain="Biotin_lipoyl (E-value: 6e-21, bitscore:
                     63.1, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSYTITVNGTAYEVTVEETGSVSAPAAAPKAAPKAAPAAAPKAA
                     APAAGAGAVKVTASVPGKVVKVAASVGQAVKAGDSVIILESMKMEIPVVAPQDGTIASI
                     DVAEGASVENGDTLATMN"
     CDS             3131..4279
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg118_4"
                     /sec_met_domain="OAD_beta (E-value: 3.9e-157, bitscore:
                     511.5, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYVTETLSNLIHQTAFFNLTWGNYLMIAVACVFLYLAIKKGFEP
                     LLLVPIAFGMLLVNIYPDIMANPEDMSNGVGGLLHYFYILDEWSILPSLIFMGVGAMTD
                     FGPLIANPISFLMGAAAQLGIYAAYFLAIFLGFNGKAAAAISIIGGADGPTSIFLAGKL
                     GQTALMGPIAVAAYSYMSLVPIIQPPIMKLFTTEKERKIKMDQLRPVSKLEKILFPIVI
                     TIVVCLILPTTAPLVGMLMLGNLFRECGVVKQLTETASNALMYIVVILLGTSVGASTSA
                     EAFLNADTLKIVVLGLVAFAIGTFGGCMLGKLLCKLTHGKINPLIGSAGVSAVPMAARV
                     SQKVGAEADPTNFLLMHAMGPNVAGVIGTAVAAGTFMAIFGV"
     CDS             4448..5860
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: HMGL-like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: PYC_OADA"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg118_5"
                     /sec_met_domain="HMGL-like (E-value: 2.5e-47, bitscore:
                     150.5, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="PYC_OADA (E-value: 2.8e-59, bitscore:
                     189.1, seeds: 434, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAELEKKPVKIVETILRDAHQSQIATRMTTEQMLPIVDKLDKVGY
                     HAVECWGGATFDASLRFLHEDPWERLRKLRDGFKNTKLQMLFRGQNILGYRPYADDVVE
                     YFVQKSAANGIDIIRIFDCLNDLRNLQTAVSAANKEKAHAQVALSYTLGDAYTLEYWTD
                     IAKRIEDMGADSICIKDMAGLLLPNKATELVTALKETVKIPIDLHTHYTSGVASMTYLK
                     AVEAGVDIIDTAMSPFALGTSQPATEVMVETFKDTPYDTGFDQKLLSEIADYFRPIRDE
                     ALDSGLLNPKNLGVNIKTLLYQVPGGMLSNLTSQLKEQHAEDKFYDVLEEVPRVRKDLG
                     EPPLVTPSSQIVGTQAVFNVLMGERYKMVTKETKDILLGKYGATVKPFNPEVQKKCIGD
                     EKPITCRPADLLDNELEKLESEMAQYKEQDEDVLTYALFPQVAMDFFKYRQAQKTKVDE
                     KAADKKNGAYPV"
     CDS             5972..7432
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HI0933_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg118_6"
                     /sec_met_domain="HI0933_like (E-value: 2.5e-128, bitscore:
                     417.0, seeds: 46, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLPVVHIYIDRSEAETWNHDEIDNLQGKINTGEYSMSKVIIIGGG
                     AAGMMAGVFAARNHHEVHILEKNEKLGKKVFITGKGRCNVTNACDTEELFPAMMSNPKF
                     LYSSFYSFTPQDVMEFFEKAGVPLKVERGNRVFPQSDHSSDIIRALERELKKAGAKIHL
                     HTAVQEIVKKPVTESVTDSVNTLESEAALTESGSAAGKGRKGKKSPDIPQEKITGVILT
                     DGTFMEGDAVIVATGGFSYQSTGSTGDGYRFARELGLKVTDIAPSLVPLKTKEDYVPKL
                     QGLSLKNTGLTIKNGKKVLYEDFGEMMFTHFGVTGPMILSASAHIGAKLAKAPNGELSA
                     YLDLKPALTREQLDARILREFEAGPNKQFKNVIGVLFPSSLTPVMLELGGIPAEKKIHD
                     ISREERQHFIDLIKAFPFTITGMGEFKEAIITRGGVSVKEINPGTMESKKISGLYFAGE
                     VLDLDAVTGGYNLQIAWSTAYLAAQAIQ"
     CDS             7618..8289
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cytidylate_kin"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg118_7"
                     /sec_met_domain="Cytidylate_kin (E-value: 1.8e-78,
                     bitscore: 252.0, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGCNIAIDGPAGAGKSTIAKKVAKELSFIYVDTGAMYRAMALYLL
                     NHGVNGENQEEIEAVCSGADISIEYKNGEQIVILNGENVNAMIRTEQVGNMASKSSANP
                     KVRAHLLKLQRTLAEKNDVVMDGRDIGTTILPNAEVKIYLTASADTRAKRRALEYEQKG
                     ESFDLDQIRKDIIERDERDMNREISPLKQADDAVLVDSSEMGIDDVVNAILNVYKEKVQ
                     K"
ORIGIN
        1 ggacgtcctt gttttccagt attttcagga ggtaataaag gttcaatgcg aagccattct
       61 tcatcagtca actcatatcg tctcaacata gtgaacaccc ctttttcttt attttatcat
      121 gaaaaaggga aataaaacat gcgttttgtg caatttttat ttttcagaca cgctctagtg
      181 tgccgacaag ttgattcttg aaacaatctt gcaggataga aataagaaat tcagacgcag
      241 gattgttcga gaaatcaact tgtcgacaca ctggtttgcg ggagagggtg aaatacagga
      301 caatacaaaa taaccgtaat accctctatt aaataggaag aaatgctcaa aaaaacaaaa
      361 tttggagaaa cctgacaaat ttttctgcta tatttttaac gaaaatgaca aataaatgtt
      421 gaaattttct gccggaaaag gtaaaattaa aatcggctaa atttttgggt taacttttaa
      481 atattctcat aaagatggag ggcaaacaag aatgagtaat gcaacacaaa gcttagcagg
      541 cacaagaatt acttctttgc ttgacgcaaa cagttttgtc gaaatcggac agggtgtaac
      601 agccagatcc acagatttca acatgactgc aaacaaggca ccatctgacg gtgttatcac
      661 cggatatggt gtgatcgatg acaaactggt ttatgtatac agccaggatg catctgtatt
      721 aaacggtact gttggtgaaa tgcatgcaaa gaagatcaca agactttatg atcttgccat
      781 gaaaacaggc gctccggtta tcggacttgt tgactgtgca ggtatccgtc ttcaggaagc
      841 aacagacgca ctggaagctt tcggacagat ctatctgaaa cagacactgg catccggtgt
      901 gatcccgcag atcacagcaa tcttcggaac atgcggcggt ggtatggcag ttatcccgtc
      961 cctgacagat ttcacattca tggaatccaa aaaaggaaaa atgttcgtca acacaccaaa
     1021 cgcactggaa ggaaacaaca cagacaaatg cgacacagca gcagctgatt tccagagcaa
     1081 agagacaggt gtgatcgatg gcgttggtac agaggatgag attcttggcc agatccgttc
     1141 cttagtatca cttcttcctt ctaataatga agacacagac aattacacag agtgtacaga
     1201 tgatcttaac cgcgtatgcg cagatcttgc aaactgtgca ggtgacacag caatcgcact
     1261 ttcccagatc gctgacaacg gtgaattctt cgagacaaaa gcagactatg caaaagacat
     1321 ggttacaggc tttatccgtt taaacggcgc tacagtaggt gctgttgcaa acagaagcga
     1381 agtatatgac gcagaaggca agaaaacaga aacatttgac ggaagcatct ctgcaagagg
     1441 cgcaagaaaa gcagcagatt tcgtgaaatt ctgcgacgct tttgatattc cggtacttac
     1501 acttacaaac gcaacaggct tcatggcaac cttatgcagc gagaagatga tggcgaaatc
     1561 cgtaggtgaa ctggtagctg cattcgcaga tgcaactgtt ccgaaggtaa atgtgatcat
     1621 cggcaaagct tacggtacag cttacgtggc aatgaacagc aaatctatcg gtgcagacct
     1681 tgtatatgca tgggataacg cagagatcgg tatgatggat gcttccctgg cagccaagat
     1741 catgtatgca gatgcagatg ctgctgaact gaatgaaaaa gctgctcagt acagagagct
     1801 tcagaatggt gttgcttccg cagcagcaag aggctatgtt gacactgtga tcagcccggc
     1861 tgacacaaga aaatatgtaa tcggtgcatt tgagatgctg ttcacaaaga gagaagatcg
     1921 tccgtctaag aaacatggaa cggtctaagc ggggtgacgc atatgaaaat gatcaaaaaa
     1981 ataacttctg tattcatgac atttctcgta atggctgcgc tggtgatcgg cagcacctct
     2041 gtggtatttg ccgcagataa ggttgatgat actgttaagt ccacactggt aactacagca
     2101 gaaggactga cagatgccat tgtccagctt aaagatgaag aaatcgagaa ttacatgagt
     2161 tcaggagatg actttacaac aagtgccatg cagtcctggc agacatccaa ggatgaactt
     2221 ggcgcaaaga aggacagcaa tggtgaaact actgtaactt tcaaagatga tcagtacaca
     2281 gttactgttc ctcttaaatt tgagaaagca gaagcaaact ttgtatatgt ctttgactca
     2341 cagggaacac cgacttccat gtctgtagat gtacagtatg gtatgggcaa gactcttcag
     2401 agagcaggtc ttaatactct gatgggtatt ggaactgtat tcgtaatgct gattttatta
     2461 agccttctga tttctctgtt cagatttatt ccgaatccgg aagcaaagaa agcagcagaa
     2521 gcaaaagcag ccaaagctgc aaaagaggca gaggcagcag ccatcgcaca gacagcacct
     2581 gcacaggcag aagagaacct tgcagatgac ggagagctgg tagctgttat cgcagcagcc
     2641 atcgcagcag cagaaggaac tacaacagac ggcttcgtag ttcgttccat ccgtaaagta
     2701 aaaagaaata gaagataatt gtcatttatt taggaggatt ttaaaatgaa aagctataca
     2761 attacagtaa atggtacagc atatgaagta actgttgaag aaacaggaag cgtatccgct
     2821 cctgcagcag ctccaaaagc agcacctaag gctgcacctg cagcagctcc gaaagcagca
     2881 gctcctgcag caggcgccgg cgcagtaaaa gtaactgctt ccgtacctgg taaagttgtc
     2941 aaagtagcag caagcgttgg acaggcagta aaagccggag acagcgtaat tattcttgaa
     3001 tccatgaaaa tggaaatccc tgtagtagct cctcaggacg gtactatcgc aagcattgat
     3061 gttgcagaag gtgcctctgt agaaaacgga gatactttag caacaatgaa ctaagacggg
     3121 aggtagtcaa atgtcttatg taacagaaac attgtccaac ctgattcacc agacagcatt
     3181 cttcaatctg acatggggca attacctgat gatcgcagta gcctgcgtat tcctttatct
     3241 tgctatcaag aagggattcg agccgcttct gcttgttcct atcgcattcg gtatgctgct
     3301 tgtaaatatc tatccggaca ttatggcaaa tccggaagac atgtctaacg gtgtaggcgg
     3361 acttcttcat tatttctaca tccttgatga gtggagtatc ttaccatccc tgatcttcat
     3421 gggtgtaggt gccatgacag acttcggtcc gctgatcgca aacccgatca gcttcctgat
     3481 gggtgctgca gcacagcttg gtatctatgc agcttacttc cttgcaatct tccttggatt
     3541 caacggaaaa gcagcagcag caatctccat catcggtggt gcagatggtc cgacctccat
     3601 tttccttgca ggtaagcttg gtcagactgc tcttatggga ccgatcgccg tggcggcata
     3661 ttcttatatg tcactggttc cgatcatcca gcctccgatc atgaaactgt tcacaacaga
     3721 gaaagaacgt aagatcaaaa tggatcagct tcgcccggtt tccaaactgg agaagatcct
     3781 gttcccgatc gttatcacaa tcgttgtctg cctgattttg cctacaacag ctccgctggt
     3841 tggtatgctc atgcttggta acctgttcag agagtgcggt gttgtaaaac agctgacaga
     3901 aacagcttcc aatgccctga tgtatatcgt agttatcctt ctgggtacat ccgtaggtgc
     3961 ttccacaagt gcagaagcat tcttaaacgc agatactctg aagatcgtag ttttaggtct
     4021 tgttgcattc gcaatcggta cattcggcgg atgtatgctt ggtaaactgc tctgcaaact
     4081 gactcatgga aagatcaacc cgctgatcgg ttccgcaggt gtatccgcag tacctatggc
     4141 agcccgtgta tcccagaaag tgggtgcaga ggcagatcct acaaacttcc ttctgatgca
     4201 cgcaatgggc ccgaacgttg ccggtgttat cggtacagcc gtagcagccg gaacattcat
     4261 ggctattttc ggtgtataat tgaatgaaat gagttccctg cttttattgc ggatgcaata
     4321 agcagtggaa cagctattcg atatagagcc acagggtatg acaactgtct gaaccctgaa
     4381 gtaatattgg ctgagttatt gagaacaaaa tgatcagtaa cgaacaaact ataaaggaga
     4441 tttaataatg gcagaattag agaaaaaacc tgttaaaatt gtggaaacca ttctccgtga
     4501 tgctcatcag tcccagatcg caacacgtat gaccacagaa cagatgcttc cgatcgtaga
     4561 taaacttgac aaagtcggct atcacgcagt agagtgctgg ggtggtgcaa cattcgatgc
     4621 atcccttcgt ttccttcacg aagatccatg ggaaagactt cgtaaattac gtgacggctt
     4681 caaaaacaca aaacttcaga tgcttttccg tggacagaac atccttggat accgtccata
     4741 cgcagatgac gttgtagaat acttcgtaca gaaatctgca gcaaacggaa tcgacatcat
     4801 ccgtattttt gactgcctca atgaccttcg taacctgcag acagcagtaa gcgctgcaaa
     4861 caaagagaag gctcatgcac aggtagctct ttcctacaca ttaggagatg cttacacact
     4921 ggaatactgg acagacattg caaaacgtat tgaagatatg ggcgctgatt ccatctgtat
     4981 caaagatatg gcaggtcttc tccttccaaa caaagctaca gagcttgtaa cagcattaaa
     5041 agaaacagtt aagatcccga tcgaccttca tacacattac acctcaggtg tagcttccat
     5101 gacttactta aaagcagtag aagcaggtgt ggatatcatc gatacagcaa tgtctccatt
     5161 tgcactggga acatcccagc ctgcaacaga ggttatggtt gagacattca aagatacacc
     5221 atacgacaca ggatttgatc agaagcttct ctccgagatc gctgactact tccgtccgat
     5281 ccgtgacgaa gctcttgaca gcggactgct caatccgaag aaccttggtg ttaacatcaa
     5341 aactttactg taccaggtac cgggcggtat gctctccaac ctgacttccc agctgaaaga
     5401 acagcacgca gaagacaaat tctacgatgt tctcgaggaa gttccgcgtg tacgtaaaga
     5461 ccttggtgaa ccgccacttg ttactccgtc ttcccagatc gttggtacac aggctgtatt
     5521 caacgtactc atgggcgaga gatacaaaat ggttacaaaa gaaacaaaag atatcctgtt
     5581 aggaaaatac ggcgcaactg taaaaccgtt taatccggaa gtacagaaga agtgcatcgg
     5641 cgatgagaaa ccgatcacat gccgtcctgc agaccttctt gacaacgagc ttgagaaact
     5701 tgagagcgaa atggctcagt acaaagaaca ggatgaagac gtattaacat acgcactgtt
     5761 cccacaggta gctatggact tcttcaaata ccgtcaggct cagaaaacaa aagttgacga
     5821 gaaagcagct gacaaaaaga acggagcata tcctgtataa ttgatcagta attaaatatg
     5881 tccaaacgaa aaaaggagct tgcgcaagca ggctcctttg cgttattatg aaagaatatg
     5941 atacccggga atataatgtg ccaatgggta tatgctgcca gtggtacata tctatattga
     6001 tcgtagcgaa gcggagacgt ggaaccatga tgaaatagac aatctgcagg gtaaaataaa
     6061 tacaggagaa tattccatga gcaaagttat aataatcggc ggcggagccg ccggaatgat
     6121 ggcaggggtt tttgcagccc gtaaccatca tgaagttcat atattagaga agaacgagaa
     6181 actgggaaag aaagtcttca tcacaggaaa aggcagatgc aatgtgacaa atgcctgcga
     6241 cacagaagaa ctctttcctg caatgatgag caatcccaag ttcctctaca gcagtttcta
     6301 ttcatttacc cctcaggatg taatggagtt ctttgagaaa gcaggtgtcc ctctgaaggt
     6361 agagcgtgga aacagagtat tcccacagtc tgaccattct tcagacatca tccgcgctct
     6421 ggagcgtgag ctgaagaaag caggagcaaa gattcatctt catactgctg tacaggaaat
     6481 cgtaaagaaa cctgtaacgg aatctgtaac agattccgta aatacccttg aatcagaagc
     6541 cgcattaaca gaatcaggat ctgctgcagg aaaaggcaga aaaggaaaaa aatcacctga
     6601 cataccgcag gagaagatca caggagtcat ccttacagac ggaaccttca tggaaggaga
     6661 tgcagtcatt gtggcaaccg gtggattctc ttatcagagt accggttcca caggtgacgg
     6721 ataccgcttc gcaagagaac tgggactgaa agtcacggac attgctccct cccttgtgcc
     6781 attaaagaca aaagaagact atgtccctaa gcttcaggga ctttccctta agaatacagg
     6841 acttaccata aagaatggaa agaaagtact ttacgaggat ttcggagaga tgatgttcac
     6901 ccatttcgga gtcacaggtc caatgatcct ctccgccagt gcccacatcg gtgcaaaact
     6961 ggcgaaagca ccaaacggcg aactgtccgc atatctggat ctgaagcctg cactcaccag
     7021 agaacagctg gatgccagga tcctgcgtga atttgaagca ggaccaaaca aacagttcaa
     7081 gaacgtgatc ggcgtacttt tcccgtcatc tctgactccg gtaatgctgg aactgggtgg
     7141 aatccccgca gagaagaaaa tccacgacat ctccagagaa gaacgccagc acttcattga
     7201 ccttatcaaa gccttcccct tcacaatcac aggaatgggt gagttcaaag aagccatcat
     7261 caccagaggc ggcgtctctg tcaaagagat caatcccgga acaatggaat caaagaaaat
     7321 ctcaggtctt tacttcgcag gcgaggtact ggatctggat gcagtgacag gtggatataa
     7381 cttacagatt gcctggtcta ccgcatatct ggcagcacag gccatacagt aagctgctta
     7441 ctatagaaac aacagaaaca agcagatgat gagtaccgtg tatgcgaatt atatctatga
     7501 ttcggttatg agcaagtagc gaagcggatt gcgaatatcc gcttgactga ttaataaaca
     7561 ttaataataa aacagagaaa atctgtttga ataatagaaa caggaggaac cacgaaaatg
     7621 ggatgtaaca tagccatcga cggacctgca ggagcaggaa agagcaccat cgcaaagaaa
     7681 gtagcgaaag aattatcatt tatctatgta gatacaggag ccatgtacag ggcaatggct
     7741 ttatatcttc tgaaccatgg cgtaaacgga gaaaatcagg aagagatcga ggctgtatgt
     7801 tccggcgctg acatctccat cgaatacaaa aacggagaac agattgtcat cctcaacgga
     7861 gagaacgtaa atgctatgat ccgcaccgaa caggtaggaa acatggcatc caaaagctcc
     7921 gcaaacccga aagtcagagc tcatcttctg aaacttcaga gaactctggc agagaaaaac
     7981 gacgtagtca tggacggcag agatatcggc acaaccatcc ttccaaacgc agaagtaaaa
     8041 atctacctca cagcaagcgc agacaccaga gcaaaaagaa gagcactgga atatgaacag
     8101 aagggagaat ccttcgacct ggaccagatc cgaaaagaca tcatcgagcg cgacgaacgc
     8161 gacatgaacc gcgaaatctc ccctctgaaa caggcagacg acgcagtgct tgtagattct
     8221 tcggaaatgg gaattgatga tgttgtaaat gcgattctta atgtatataa agaaaaggtg
     8281 cagaaatgat cagataactg cctgtagttc atcagaagat gacacacgca aagatatctg
     8341 acacaggatt tcacgctct
//
