LOCUS       gnlProkkaMBPGOLJE_38   12813 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MBPGOLJE_38.
ACCESSION   gnlProkkaMBPGOLJE_38
VERSION     gnlProkkaMBPGOLJE_38
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 19:50:25
            Original ID  :: gnl|Prokka|MBPGOLJE_38
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12813
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12813
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[8744:10943]"
                     /cutoff="5000"
                     /detection_rule="(hr-t2pks-ksa and (t2fas or APE_KS2 or
                     ketoacyl-synt))"
                     /neighbourhood="20000"
                     /product="HR-T2PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      8745..10943
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(hr-t2pks-ksa and (t2fas or APE_KS2 or
                     ketoacyl-synt))"
                     /neighbourhood="20000"
                     /product="HR-T2PKS"
                     /protocluster_number="1"
     cand_cluster    1..12813
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(hr-t2pks-ksa and (t2fas or APE_KS2 or
                     ketoacyl-synt))"
                     /kind="single"
                     /product="HR-T2PKS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12813
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="HR-T2PKS"
                     /region_number="1"
                     /rules="(hr-t2pks-ksa and (t2fas or APE_KS2 or
                     ketoacyl-synt))"
                     /tool="antismash"
     CDS             complement(432..977)
                     /locus_tag="ctg38_1"
                     /transl_table=11
                     /translation="MKVFNCIFGILSIIGAIYCMFYPGLTFLNTGWIVTILLGVWGICS
                     VIDYFAKRKKAKAEQSEAIMGTLGLVVGIAAAVISILAMFMPGIRLMFDVIILCIFSGW
                     LVVDGISSVAMSLKVKKASSSGAWLIPLFCGILVIIGGIYGFFHLIFAAQTIGFMIGVL
                     LSIYGVKLILSAFEKPSV"
     CDS             complement(996..3008)
                     /locus_tag="ctg38_2"
                     /transl_table=11
                     /translation="MIXXXXLALAATLIASSALCGCQQSDSSTSAKFNSDVKDASKYTA
                     DENAQVYKTLDFSDEQEKEFAKKGFITAPDKLEIKTENGTVAWSQTAYDFIRNSSTPDS
                     ANPSLWRNTELNSLYGLFEVVDGVYQVRGYDVANVTFVKSDNGWIVFDCTTSSETAKAA
                     LELLESKFGKAHIAAVVVSHAHIDHYGGIGGLIDEKNVADSSLPLDEQIKSGKTLIIVP
                     EGYEKAVMEENVFAGNAMKRRTNFQYGSLLDKGGKGSLSVGIGLTPSSGTTTYISPSYE
                     VKKATETIKVDGVEMVFQLXXXXPAEMNTYLPKYKALWMAENCSGTMHNLYTLRGAEVR
                     DGNAWAQYIMEAKELFGDKTEVVFQAHNWPHWGNDVINDYMANTASVYKYIFSQTLMYI
                     NQGYTSTEIANMMELPDELNKVWYTRQYYGTLKHNVKAVYQKYMGWYDENPIHLDELEP
                     TEYSKKLVEYLGDTDKVLEMAKKDFDKGEYQWVAQITNTLVYADPENKDARYLCADALE
                     QLGYQAESGAWRNAYLTGAYELRNGTKNYPNSEGSGATALGMSTETMLDYLGICLDEKK
                     LEDQNLVINLEVTDKNAKYLLRINHGVLIYSQEKWSDKADATIKTKSAGILGIAQNNQK
                     LMDAGIEKVEGNSDIIKTLTSSVAEFPLYFNIIEP"
     CDS             3196..3918
                     /locus_tag="ctg38_3"
                     /transl_table=11
                     /translation="MRIAIVDDCENERNELCKRLSQSSFSRSYDIEICEYNSGTDFLNE
                     AMQNRFDLVFMDIYMEKENGIDAAQKLRKFDKDCLLVFTTTSTDHALEGFRVRALHYLV
                     KPYSDEELDMLLDEISQKISVEEKYIEIPSASDSLRIKLCDILYAEHFKHCIHIHCTDK
                     SEKSVRSTFAEFVMLFDDGDNFFVCNRGIIVNLEHIRDMNGNEFVLDNGERISISRSLV
                     KSAKSTFGEYIFGRRDLH"
     CDS             3915..5228
                     /locus_tag="ctg38_4"
                     /transl_table=11
                     /translation="MTNVFCPMIELGAIIPGVVLAYLPIKKHLKLSKLRLFPVMILSLV
                     CLCTLCGFVCYRYNLKSFVLAIPIVLALSAAYCCSLKTSMWKSVSVLLAVCGVFACIAS
                     ITRAVDSITFPQNTTPWFEIQSAVLFNILCWMFVILAWYPATHGVSELLDDENIAQTWY
                     VFWILPIIFILLNFFIIPWNPNILHTGRIMQGYIVISVSLLVLLLIFYALLYFIAKSLN
                     RNNKLAQKNQFLNMQRAQYDALKVAIEETRQARHDMRHHFAVLNALAEQKNWEELEKYL
                     SSASQNIPDTELVLCKNHAVNAIIGHYYSKYKSNGIPFKLKIDIPEKLTVSESDICLVI
                     ANLLENAFEASMKLDRDKRQIKMYARPHSEKILLISVENAFNGEITEKDGFFGSSKRNG
                     NGIGTQSVRRIAEKDGGYCRFSHENGIFTADVMLHGKN"
     CDS             complement(5279..6301)
                     /locus_tag="ctg38_5"
                     /transl_table=11
                     /translation="MIDARKHTLDSVKKLTDYSDFNLYKMDICYDYSIDKIIDRGIFDD
                     ESALGAILQEVLPDYPVNLKMPNFGCSAFTMKNPDSVMMGRNYDFKNDTSSMLVYCSPK
                     DGYRSVAFAALDNVGANNPELSDETRLATLLSPFISLDGINEKGVSIAVLTLDSKPVRQ
                     QSGKPVIATTLAIRLILDRAASTEEAVTLFEKYDMFASSGRDYHFYVTDSNGDGRVIEY
                     DCNSDDRKLVVTKSPAVTNFFVMYKNFVKPYQKNGVYGHGRERYDKIINILEKNNSYTK
                     ETAWEALVSASQAPNPNDITSNTQWSIVYDNTNLTADISIRRDWNTVTKYSLKENKITE
                     "
     CDS             complement(6471..7532)
                     /locus_tag="ctg38_6"
                     /transl_table=11
                     /translation="MKKVILTGDRPTGRLHVGHYAGSLKERVKLQNSGEYDDIYIMIAD
                     AQALTDNAEHPEKVRQNILQVALDYLACGIDPNKSTIFVQSMIPELTELTFYYMNLVTV
                     SRVQRNPTVKAEIQMRNFEASIPVGFFCYPISQAADITAFRATAVPVGEDQLPMLEQCK
                     EIVHKFNSVYGETLTEPQIILPSNKACLRLPGIDGKAKMSKSLGNCIYLAEEPEDIKKK
                     VMSMFTDPNHLRVEDPGKVEGNPVFIYLDAFCRDEYFAEFWNDYSCLDELKAHYQRGGL
                     GDVKVKKFLNNVMQEELRPIRERRKEWENHLPDVLDILKEGSKVAKETAAKTLEDVRHS
                     MRIDYFTDNNLLK"
     CDS             7774..8460
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1141:acyltransferase (Score: 83.7; E-value: 2e-25)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_7"
                     /transl_table=11
                     /translation="MEYNYHKNAGQLAFIKFVKGLVHLLIRPKVEWKDKSLKKSLKGKP
                     VVFVCNHTHHFDGVVISSVLSRYKPYMLVKKSWYDKSGTGSFIRICRSIPVDFDTMDTN
                     WYAQSEGAVENGYSMLIFPEGGIAREGKMLPFKPGAALLAAKKGLDIIPIASLGEYKIL
                     FGKRQKILIGNPIKSECPENVRYSKYAKEISAEAEKQVKKLYLELEEKYGKGKVYYKED
                     FSSENL"
     CDS             8501..8743
                     /NRPS_PKS="Domain: PP-binding (6-75). E-value: 1.1e-11.
                     Score: 37.0. Matches aSDomain:
                     nrpspksdomains_ctg38_8_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_8"
                     /sec_met_domain="PP-binding (E-value: 2.3e-12, bitscore:
                     37.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNAIADQIKEMLVENLRIPENILTYDSELFGDEIGLDSIDSIEI
                     VAGIDTLFGIDMTGADREHFQSIRALTEYVESKQG"
     aSDomain        8519..8725
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg38_8_PP-binding.1"
                     /evalue="1.10E-11"
                     /label="ctg38_8_PP-binding.1"
                     /locus_tag="ctg38_8"
                     /protein_end="75"
                     /protein_start="6"
                     /score="37.0"
                     /tool="antismash"
                     /translation="DQIKEMLVENLRIPENILTYDSELFGDEIGLDSIDSIEIVAGIDT
                     LFGIDMTGADREHFQSIRALTEYV"
     CDS             8745..10943
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (66-399). E-value:
                     3.3e-50. Score: 163.1. Matches aSDomain:
                     nrpspksdomains_ctg38_9_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     HR-T2PKS: hr-t2pks-ksa"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     HR-T2PKS: t2fas"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 80.3; E-value:
                     2.4e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg38_9"
                     /sec_met_domain="hr-t2pks-ksa (E-value: 1.5e-106, bitscore:
                     346.3, seeds: 7, tool: rule-based-clusters)"
                     /sec_met_domain="t2fas (E-value: 3.9e-23, bitscore: 71.5,
                     seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADKKRCVVTGLGLICGVGDNVKDCWDAVTLGHSGIDEVKSVDTS
                     NCYAHKGAEVDKASSELSPENYDRSSLLCIHAANEAFEDANIDASEKNIGVILGSCVGG
                     AASIDKYYTDEIKGDGGKKEDIFKMGASAIANNVSAHFGLEGITANIVNACAAGTMSIG
                     YACDLIREGKGDVFIAGGSDSFSSLAFSGFHALHALDENACSPFNHSTGITLGEGSGIL
                     VIESYEHAVERGAKIYCEILGSGVSSDAYHITAPRPDGEGQMSAIRRAVESSALSFDDI
                     DYINAHGTGTAKNDEAEFLSLHTLFDGNDHLSVSSTKSMTGHCLGAAGSIEAVFSVKAI
                     KENLVPPTIGYSDEDLKVLSEKAGNIDFIPNKSHTKDVHYAMSNSFAFGGNNASIIFSD
                     NEHDIPDNSKNEKIYITGISKLTGTKTDEHSLNCNLTSEDYDKHGIKVAFYRKLDRFSQ
                     LQLLSGMDALADADIKIDKDNEYKTGIVIGTADGPMTEIVDFQKKAITRGTEKGSAFSF
                     PNTVYNAAGGYLSIFSGIKGYNATVANGNQAGLQSICYAADILADGNESVMLAAGTDEN
                     TKTNLELYTKAELLEKPLGEGSVTLVLETEESANGRNARKYAEIKGYAQAHRPVSYDNS
                     EVDSKAVVEVIEKACVNAGIEADNIDFVCCDDRKIIKTLMPCYDVSQEIGNARAAASAM
                     TAAYAAELLSDSEKNYEYGLALSMGAGGTYSAVILKKA"
     aSDomain        8943..9941
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg38_9_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="3.30E-50"
                     /label="ctg38_9_PKS_KS.1"
                     /locus_tag="ctg38_9"
                     /protein_end="399"
                     /protein_start="66"
                     /score="163.1"
                     /tool="antismash"
                     /translation="YDRSSLLCIHAANEAFEDANIDASEKNIGVILGSCVGGAASIDKY
                     YTDEIKGDGGKKEDIFKMGASAIANNVSAHFGLEGITANIVNACAAGTMSIGYACDLIR
                     EGKGDVFIAGGSDSFSSLAFSGFHALHALDENACSPFNHSTGITLGEGSGILVIESYEH
                     AVERGAKIYCEILGSGVSSDAYHITAPRPDGEGQMSAIRRAVESSALSFDDIDYINAHG
                     TGTAKNDEAEFLSLHTLFDGNDHLSVSSTKSMTGHCLGAAGSIEAVFSVKAIKENLVPP
                     TIGYSDEDLKVLSEKAGNIDFIPNKSHTKDVHYAMSNSFAFGGNNASIIFSD"
     CDS             10959..11693
                     /NRPS_PKS="Domain: PKS_KR (3-167). E-value: 2.7e-16. Score:
                     51.8. Matches aSDomain: nrpspksdomains_ctg38_10_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     227.2; E-value: 3.6e-69)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_10"
                     /sec_met_domain="adh_short (E-value: 2.9e-40, bitscore:
                     127.8, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 5.7e-35, bitscore:
                     111.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTALVTGSSRGIGKACALKLAELGYDIAVNCNSNLEMAQKAVD
                     EITSLGRKAVAYKANTADIDEVKDMFRSIQQDFGGIDVLVNNAGVVDDAYLLMIKDESL
                     ERSLDINIKGYFNCARQASLKMLRKKSGIIINISSVSSVLAVEGQSVYSATKGAVNAMT
                     HTLAKELAKYGIRVNAVAPGFIETEMMNGIPEELQKKYLEAIPEKRFGTVQDVANVVGQ
                     LCSDDFSYMTGQVLVLDGGLSL"
     aSDomain        10968..11459
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg38_10_PKS_KR.1"
                     /evalue="2.70E-16"
                     /label="ctg38_10_PKS_KR.1"
                     /locus_tag="ctg38_10"
                     /protein_end="167"
                     /protein_start="3"
                     /score="51.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TALVTGSSRGIGKACALKLAELGYDIAVNCNSNLEMAQKAVDEIT
                     SLGRKAVAYKANTADIDEVKDMFRSIQQDFGGIDVLVNNAGVVDDAYLLMIKDESLERS
                     LDINIKGYFNCARQASLKMLRKKSGIIINISSVSSVLAVEGQSVYSATKGAVNAMTHTL
                     A"
     CDS             11690..12145
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1270:UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine
                     (Score: 94.1; E-value: 1.6e-28)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_11"
                     /transl_table=11
                     /translation="MMNLLEINQRIKQRPPFQMIERVTELEPNVSATGIKNVSVNEPYF
                     AGHFPDTPIMPGVLLIESAAQLCSLVFAPESVEEDKLYVLLKVKDFKMLRPVIPGDTLI
                     ISVNVTMSTKSAFEFACVIKVDGEVRAKGSLLFTTMDKNAVYKPSQE"
     CDS             12148..12813
                     /locus_tag="ctg38_12"
                     /transl_table=11
                     /translation="MKVLVLNGSPKGEKSNTLNITKAFLDGFSADTEVEYITVKKETIK
                     PCMGCFSCWSRTPGKCVIKDDMQKIYEKINSADIIIESFPLYFFGMPSQMKALTDRCLP
                     YMLPYSGNVAEDKEASFHELRDEAMHEKRLAVITTCGYVSAEPMYPALIKQLDLICGNG
                     NYTMIKCPEGELFIAEKAERQRKAYLDSITEAGREFCENRCLCDETMKKISKPILSPKG
                     "
ORIGIN
        1 tgtgaccctc tgcttgtaag gcagatgctc tcccagctga gctatgctcc cacattttta
       61 taatcggaaa gcactcccgt taagaagtgc tttccgtttt ggaggcgaca cccggatttg
      121 aaccggggcg tcagagtttt gcagactcgt gccttaccac ttggctatgt cgccgaatac
      181 tgagcaatgt cactcaacag gcattattct atcataataa aattcatttg tcaatactga
      241 atttgcattt taacaacaaa atttaacgga aaatttctac actgatattt tatgcatcaa
      301 acagaaaaat gacacctctg tttttgattc ctcataaagc cccgaaccct caaagatgca
      361 atactctgaa ggttcgggat tttggggtta tcatactttt cttaaaaaga gaagaaaaca
      421 agataagtat cttacacgct cggcttttca aatgccgaaa gaataagctt tacaccgtag
      481 attgacaaaa ggacaccaat cataaatccg attgtctgtg cggcaaatat aaggtggaaa
      541 aatccgtaga taccgccgat tatgacgagt attccgcaga aaagcggaat aagccatgca
      601 cctgaggaag atgctttttt gaccttgagt gacattgcaa cggacgagat accgtccact
      661 acaagccaac ctgagaaaat gcagagaatg ataacatcaa acataagtct tatgcccggc
      721 ataaacatag caagaattga aattactgcc gctgcaatgc cgacaacaag accgagtgtt
      781 cccattatcg cttcactctg ttcagccttt gcctttttgc gttttgcaaa gtagtcaatc
      841 acggagcata ttccccatac tccgagaaga attgtcacta tccaaccggt attaaggaag
      901 gtaagtcccg gatagaacat acaataaatc gcaccgatta tcgacaatat gccgaaaata
      961 caattaaata ctttcatagt cacctcatac tttaattagg gttcaataat attgaaatac
     1021 agcgggaatt cggcaacgct tgatgtaagg gttttgatga tgtcactgtt gccctcaacc
     1081 ttttcaatgc cggcgtccat aagtttctga ttgttctgtg caatgccgag aatacctgcg
     1141 ctcttggttt tgattgttgc gtcagcctta tcgctccact tttcctgtga atagataagc
     1201 acaccgtgat ttatgcgaag aagatatttt gcgtttttat cggtcacttc aagattgatt
     1261 acaaggttct gatcttcaag cttcttttcg tcaagacaga ttccgagata atccaacatt
     1321 gtttcggtac tcataccgag agctgttgca cctgaacctt cggaattcgg ataatttttt
     1381 gtaccgttac gaagctcata agcacctgta agataagcgt ttctccatgc accgctttca
     1441 gcctgatagc cgagctgttc gagtgcgtct gcgcaaagat agcgggcgtc tttattttcg
     1501 ggatctgcat atacaagtgt gtttgtaatc tgtgcaaccc actgatactc tcccttgtca
     1561 aagtcttttt tagccatttc aagaaccttg tctgtgtcgc cgagatactc tacaagcttc
     1621 tttgaatatt ctgtcggttc aagctcatca agatgaatgg ggttttcgtc ataccaaccc
     1681 atatacttct gataaaccgc ctttacattg tgcttgagag ttccgtaata ctggcgtgtg
     1741 taccaaacct tgttgagttc atctggaagc tccatcatat ttgcaatttc ggttgatgta
     1801 tagccctgat tgatgtacat aagtgtctgt gagaatatgt acttatagac agaggctgtg
     1861 tttgccatgt agtcattgat tacatcgttg ccccaatgag gccagttgtg agcctggaaa
     1921 actacttcgg ttttatctcc gaaaagctcc tttgcctcca taatgtactg cgcccacgca
     1981 ttgccgtcac gaacctctgc gcctctgagt gtgtagaggt tgtgcattgt gccggaacag
     2041 ttttcagcca tccacaaagc cttgtatttt ggaaggtagg tgttcatctc ggcaggcgnn
     2101 nnnnnnnnaa gctggaacac catttcaaca ccgtcaacct tgatggtttc ggtagctttc
     2161 tttacctcat aagacggtga aatgtatgtt gttgtgccgc ttgaaggggt aagaccgata
     2221 cctaccgaca aactgccctt accgccctta tcaagcaatg atccgtactg aaagttggtt
     2281 ctgcgtttca ttgcgtttcc tgcaaaaaca ttttcttcca taacagcctt ttcgtagcct
     2341 tcgggaacga taatgagcgt tttgccggac ttaatctgtt catcaagcgg aagtgatgaa
     2401 tctgcaacat tcttttcgtc aataagtccg ccgataccgc cgtagtggtc aatgtgagcg
     2461 tggcttacaa caacagcggc aatatgcgcc ttgccgaact tagattcaag cagttcaagc
     2521 gccgcctttg cagtttcgga gcttgttgta cagtcaaaaa caatccagcc gttgtcgctc
     2581 tttacaaagg ttacattggc aacatcgtag cctctgacct gataaacacc gtcaacaact
     2641 tcaaaaagtc cataaagcga gttaagctcc gtgtttctcc aaaggcttgg gtttgcactg
     2701 tcgggagttg acgagtttct gataaagtca tatgctgtct ggctccatgc aacagttccg
     2761 ttctcggttt tgatttcgag tttgtcgggt gctgttataa agcccttttt tgcaaattcc
     2821 ttttcctgtt catcggaaaa gtcaagggtc ttatacacct gtgcgttttc gtcagccgta
     2881 tattttgacg catcctttac atcgctgttg aattttgcgg atgtactgct gtcgctctgc
     2941 tgacatccgc aaagtgcaga tgaggcaatc aatgttgccg ccaaagcaag gcnnnnnnnn
     3001 nnaatcatag aatatttcct ccgtgttttt atctgtccat gattttttgg tttaagctga
     3061 attataataa ataattgtca tttagtccat acatttggca caaagtgaaa atttttgtca
     3121 cgaaatgcaa attaaagtca ctatttgaga tattatgtga tacaataaga gtgataatta
     3181 tgcaggaggt acggtatgag gattgcaata gttgatgatt gcgaaaatga gcgaaatgaa
     3241 ctttgcaaaa gactttctca aagctcattt tcaaggtcat atgatattga aatttgcgaa
     3301 tataacagcg gaacggattt tctgaatgag gcaatgcaga acagatttga ccttgttttt
     3361 atggatatat atatggaaaa ggaaaacgga attgatgcgg cacaaaagct gaggaagttt
     3421 gacaaagatt gtctgcttgt tttcacaacc acatcaaccg accacgcact tgaaggtttt
     3481 agggttcggg cattgcacta tcttgtgaag ccgtacagcg atgaagagct tgatatgttg
     3541 cttgatgaga tttcgcagaa aatttccgtt gaagaaaaat acattgaaat accctctgca
     3601 agtgactcgt tgcgtataaa gctttgcgac attttgtatg ccgagcattt taagcactgc
     3661 atacatattc attgtacgga caaatccgaa aagtctgtgc gcagtacatt tgccgaattt
     3721 gtaatgctgt ttgatgacgg ggataatttc tttgtgtgca accgaggaat catagtaaat
     3781 cttgaacaca tcagggatat gaacggcaat gaatttgttc ttgacaacgg tgaaagaatc
     3841 tccataagtc gaagtcttgt aaaaagcgca aaaagcacct ttggcgaata tattttcggc
     3901 aggagggatt tgcattgaca aatgttttct gtccgatgat tgaactcggt gcaatcatcc
     3961 ccggtgttgt acttgcatat cttccgataa aaaaacatct caaactatca aagctcaggc
     4021 tgtttcctgt gatgatttta tcacttgtgt gcctttgtac attgtgcggt tttgtttgtt
     4081 acagatacaa tctgaaatcg tttgtgcttg caataccgat agtgcttgct ctttcggcag
     4141 catactgttg ttcactcaaa acatccatgt ggaaatcggt gagtgtgtta cttgcggtat
     4201 gcggagtgtt tgcctgcatt gcgagcatta cacgggcggt tgattcgata acatttccgc
     4261 agaacacaac gccgtggttt gaaattcaat cggctgtgct gttcaatatt ctatgctgga
     4321 tgtttgtaat tcttgcatgg tatcctgcaa cacacggtgt gagtgaactg ctcgatgatg
     4381 aaaacattgc ccagacatgg tatgtattct ggattttacc gataatattc atcttgctca
     4441 acttttttat aatcccatgg aatcctaaca ttctccatac aggaagaatt atgcagggtt
     4501 acattgttat cagcgtatca cttcttgtgc tgttgctcat tttctacgct ttactgtatt
     4561 ttattgcaaa aagtctgaat cgcaataaca aacttgctca gaaaaatcaa tttttgaata
     4621 tgcagagggc acagtatgac gcattaaaag tcgctattga agaaacccgt caggcacggc
     4681 atgatatgcg acatcacttt gccgtactta atgctcttgc cgagcaaaag aactgggaag
     4741 aacttgaaaa atacctttcg tcagcatcgc agaatattcc cgacacagag cttgtactct
     4801 gtaaaaacca cgctgttaat gcgattatcg gacattatta ttcaaaatac aagagcaatg
     4861 gtattccgtt taaactaaaa attgacatcc ccgaaaagtt gacagtttcg gaatccgata
     4921 tctgtcttgt aatcgcaaat ttgcttgaaa atgcatttga ggcgagcatg aagcttgaca
     4981 gagataaacg gcagattaaa atgtatgccc gtccgcattc cgaaaagata ttgcttattt
     5041 ccgtagagaa tgctttcaac ggagagatta ccgaaaagga cggatttttc ggttcgtcaa
     5101 agcgaaacgg taacggtatc ggtacgcagt cggtacgcag aattgccgaa aaagacggcg
     5161 gttattgcag attttctcac gaaaacggaa tttttacggc ggatgttatg ctgcacggca
     5221 aaaactgaat cggacattat taaagggaag aaaccatttc ggtttcttcc ctgttttttt
     5281 attccgtaat tttattttct tttagcgaat attttgtcac cgtgttccaa tctcggcgga
     5341 ttgaaatatc agcggtaagg tttgtgttgt cataaacaat cgaccattga gtattgcttg
     5401 ttatatcgtt cggattcggt gcttgtgatg ccgaaacaag agcctcccat gctgtttctt
     5461 ttgtgtaact attattcttt tcaagaatat tgattatctt atcataccgc tctctgccgt
     5521 gaccgtaaac accgtttttc tgataaggct ttacaaaatt tttgtacatc acaaaaaagt
     5581 ttgtaacggc aggcgatttt gtaacaacaa gctttcggtc atcgctgttg caatcgtact
     5641 caataacacg accgtcaccg tttgaatcgg taacataaaa gtgataatct cttccgcttg
     5701 aggcgaacat atcgtatttt tcaaaaagtg taaccgcctc ttcggttgac gcagctctgt
     5761 caagtataag acggattgca agcgttgtgg cgataacagg ctttccgctt tgctgacgga
     5821 cgggcttgct gtcaagtgtg agaactgcga ttgacacgcc cttttcattg attccgtcaa
     5881 ggctgataaa cggtgagagc aaggttgcaa gccttgtttc atcactcaac tcggggttgt
     5941 ttgcacctac attatcaagt gccgcaaacg caaccgacct gtagccgtcc tttggcgaac
     6001 aatacacaag cattgacgag gtgtcgttct taaaatcata gtttcgcccc atcattacgc
     6061 tgtcgggatt tttcattgta aaggcactgc acccgaaatt cggcatttta agattgacgg
     6121 gataatcggg cagaacctcc tgcaaaattg caccgagagc cgactcatca tcaaaaatcc
     6181 ctctgtcaat gattttatca atgctgtaat cgtagcatat atccatttta taaaggttaa
     6241 aatcgctgta atcggtcagc tttttaacag aatcaagcgt atgctttctt gcgtcaatca
     6301 taatgtatcc tccttaaaac ggggtgtttt caacgcaata atagcataat atttttattt
     6361 tttcaacaat tttgagtcaa ttcgcaataa ttttttcata agaaaaatcg gaaagacaga
     6421 atttttgatt tctgtccttc cgacctgtat tttacatatt gaattttaaa ttatttaaga
     6481 agattattgt ctgtaaaata atcgattctc atagaatgac ggacatcctc aagtgttttt
     6541 gcggcagttt cctttgcaac cttactgccc tctttgagaa tatcgagaac atcgggaaga
     6601 tgattttccc attcttttct gcgttcacga ataggacgaa gctcctcctg cataacattg
     6661 ttaaggaatt tcttaacctt gacatcaccg agtccgccac gctgataatg agccttgagt
     6721 tcgtcaagac agctgtaatc attccaaaat tccgcaaaat actcgtcacg gcagaatgcg
     6781 tcaagataga taaacacggg attgccctca accttgccgg gatcctcaac acgaagatga
     6841 ttcgggtcgg taaacattga cataaccttt ttcttgatat cctcgggttc ttctgcaaga
     6901 taaatgcagt tgccgaggga tttgctcatc tttgccttgc cgtcaatacc gggcagtcgc
     6961 agacaagcct tgttgctcgg aagaataatc tgcggttccg taagagtttc gccgtaaacg
     7021 gaattgaact tgtgaacaat ctccttgcat tgttcaagca tcggaagctg atcctcgccg
     7081 acaggaacgg cagttgcacg gaatgccgtg atatcagccg cctgactgat tggataacag
     7141 aaaaatccca caggaatgct tgcctcaaaa ttacgcatct gaatttctgc cttaacggtg
     7201 gggttacgct gaacacggga cacggttacg aggttcatat aatagaaagt aagctctgta
     7261 agctcgggaa tcattgactg aacaaaaatt gttgacttgt tcggatctat tccgcaggca
     7321 aggtagtcga gcgcaacctg caaaatattc tgtcttacct tttcgggatg ctcggcattg
     7381 tcggtaagag cctgagcgtc tgcaatcata atgtatatat catcatattc gcccgaattc
     7441 tggagcttta ctctctcctt gagcgaacct gcatagtgac cgacatgaag tctgcccgta
     7501 ggacggtcac ctgttaaaat tacttttttc ataggtttct cctttgttta ccttgattca
     7561 aaggcaaaat tcttttctat gattatatca ccataaacaa cagccgtcaa catttgtaaa
     7621 aaagctaaaa agaaaaatat tccataataa ttcccatata ttttatgcca caaaattcga
     7681 cagaatgttg cataagacac acgcaaaatt catttgaccg ttgaattttt tttaaataaa
     7741 aatataatat tttaaaaaac gagggtaaag agtatggagt acaattatca taaaaatgca
     7801 ggacagcttg cattcataaa atttgtaaaa ggtcttgtgc atcttcttat tcgcccgaag
     7861 gttgaatgga aggacaagag ccttaaaaag agcctcaagg gcaagcctgt tgtgtttgta
     7921 tgcaaccaca ctcaccactt tgacggagtt gtgataagct ctgtactcag cagatacaag
     7981 ccgtatatgc ttgttaaaaa aagctggtat gacaagagcg ggacaggctc gtttatccga
     8041 atttgccgca gtattcccgt tgactttgac accatggaca caaactggta tgcacaaagt
     8101 gagggtgcgg ttgaaaacgg atattcaatg cttatcttcc ccgagggcgg aattgcaaga
     8161 gagggcaaaa tgctcccgtt caagcccggt gcggcattgc ttgcggcaaa aaaaggtctt
     8221 gacataatcc cgattgcatc tttgggtgag tataaaattc tttttggaaa gaggcagaaa
     8281 attttaatcg gcaatccgat aaaatccgaa tgtcccgaaa atgttcgcta ctcaaaatat
     8341 gcaaaagaaa taagtgccga agccgaaaag caggtcaaaa agctttatct tgagcttgaa
     8401 gaaaaatacg gcaaaggcaa ggtttattac aaagaagatt tttcttcgga aaatttataa
     8461 taaaatcaaa aaaatcaaaa ttttaagtga ggtaattaaa atgaacaatg ctattgcaga
     8521 tcagattaag gaaatgctcg tagaaaacct tagaattccc gaaaacattc ttacatacga
     8581 ttcagaactt ttcggtgacg aaatcggtct tgactcaatc gactcaatcg aaatcgttgc
     8641 aggcatcgac acacttttcg gtattgatat gacaggtgca gaccgtgagc acttccaatc
     8701 aatcagagca cttacagaat atgtagaaag caagcagggt taatatggct gacaaaaaga
     8761 gatgtgttgt cacaggactc ggacttatct gcggcgtcgg tgacaatgta aaggattgct
     8821 gggatgccgt aacactcggt cactccggca ttgatgaggt taagtcggtt gacacctcaa
     8881 actgttatgc acacaagggt gcagaggttg acaaggcatc gtcagagctt tctcccgaaa
     8941 actatgaccg ttcttccctt ctctgtattc atgccgcaaa cgaggctttt gaagatgcaa
     9001 acattgacgc atccgaaaag aacatcggtg ttattcttgg cagttgtgta ggcggtgcgg
     9061 caagcattga caaatattac acagacgaaa tcaagggtga cggcggtaaa aaagaagata
     9121 ttttcaaaat gggtgcttcg gcaattgcca acaatgtttc cgctcatttc ggacttgagg
     9181 gcattaccgc aaacatcgtc aacgcttgtg cggcaggcac aatgagcatc ggctatgcct
     9241 gtgaccttat ccgtgagggc aagggtgatg tgttcatcgc aggcggttcg gacagctttt
     9301 cttcacttgc attcagcggt ttccacgctc tccatgcgct tgacgaaaac gcctgttccc
     9361 cgttcaatca cagcacaggt atcacgctcg gcgagggttc gggtattctt gtaatcgaaa
     9421 gctacgaaca cgctgttgaa cgaggcgcaa agatttactg tgaaattctc ggttcgggtg
     9481 taagcagtga cgcttaccac attaccgctc cccgtcccga cggtgaaggt cagatgagtg
     9541 caatcagaag ggctgttgaa agctctgctc ttagttttga cgatatcgac tacataaacg
     9601 cacacggaac tggtactgcc aaaaatgacg aggctgaatt tctttcactt cacacacttt
     9661 ttgacggcaa cgaccacctt tctgtcagct caacaaaatc tatgacaggt cattgcctcg
     9721 gtgcggccgg ctcaattgag gctgtatttt ccgtaaaagc aataaaagaa aacctcgttc
     9781 cgcctacaat cggctactcc gatgaggatt tgaaggtgct ttccgaaaag gcgggcaaca
     9841 ttgactttat tccgaacaag agccacacaa aagatgttca ctatgcaatg tcaaactcat
     9901 ttgcattcgg cggcaacaac gcaagcatca ttttctcgga caacgagcat gatattcccg
     9961 acaacagtaa aaatgaaaaa atttacatta cgggcatttc aaagcttaca ggcacaaaga
    10021 ctgacgaaca cagccttaac tgcaacctta cctccgaaga ttatgacaaa cacggaatca
    10081 aggttgcatt ttacagaaag cttgaccgtt tcagccagct ccagcttttg agcggtatgg
    10141 acgcacttgc agacgctgac attaaaattg acaaagacaa cgaatataaa acaggtattg
    10201 taatcggcac ggctgacggc cctatgaccg aaattgttga tttccagaaa aaggcaatca
    10261 caagaggtac cgaaaagggc agtgcttttt cattcccgaa tacggtttac aatgccgcag
    10321 gcggttatct gagcattttc tcaggcatca agggctacaa cgcaactgtt gcaaacggca
    10381 atcaggcagg actgcagagt atttgctatg ccgctgatat tcttgcagac ggcaacgaaa
    10441 gcgttatgct tgccgcaggt accgatgaaa atacaaagac aaaccttgaa ctctatacaa
    10501 aggccgaatt gcttgaaaaa ccgctcggtg agggctctgt aactctcgtt cttgaaacag
    10561 aggaaagtgc aaacggcaga aatgcacgca agtatgcaga aattaagggc tatgcacagg
    10621 ctcaccgccc tgtatcttat gacaactcag aggttgacag caaggctgtt gttgaggtta
    10681 tcgaaaaggc ttgtgtgaat gccggcattg aggcagacaa tatcgacttt gtatgctgtg
    10741 acgacaggaa gattatcaag acgcttatgc catgctatga tgtatcgcag gaaatcggca
    10801 atgcaagagc cgcagcaagc gcaatgacag cggcatatgc ggctgagctt ctttctgaca
    10861 gcgagaaaaa ttacgaatac ggacttgctc tttcaatggg tgcgggcgga acatactctg
    10921 ccgtaatcct gaagaaagcg taaaaatcgg aggtaaatat gagcaaaacc gctcttgtaa
    10981 caggttcatc aaggggcatt ggcaaggctt gcgctttaaa gcttgcagag cttggatatg
    11041 acattgccgt gaactgcaat tcaaatttag aaatggctca aaaggctgtt gacgaaatta
    11101 catcactcgg cagaaaagcc gttgcctaca aggcaaacac ggcagatatt gacgaagtaa
    11161 aggatatgtt ccgcagtatt cagcaggact tcggcggaat tgatgtgctt gtcaacaacg
    11221 caggtgtggt tgacgacgct taccttttga tgattaaaga cgagtcgctt gaaagaagtc
    11281 ttgacattaa tatcaaagga tatttcaatt gtgcaagaca ggcatcgctt aaaatgctcc
    11341 gcaaaaagag cggaatcatc atcaacattt cttccgtaag ctctgttctt gcagttgaag
    11401 gtcagtcggt ttacagtgca acaaagggtg cggtaaacgc tatgactcac acgcttgcaa
    11461 aggaacttgc aaagtacgga atcagagtaa acgcagttgc acccggtttt atcgaaaccg
    11521 aaatgatgaa cggcattccc gaagaattgc agaaaaagta tcttgaggct attcccgaaa
    11581 agagattcgg cacagttcag gatgtcgcaa atgtcgttgg acagctttgc agtgacgatt
    11641 tttcatatat gacaggtcag gtgcttgtgc ttgacggagg actcagctta tgatgaatct
    11701 gcttgaaatc aatcaaagaa taaaacaaag accacccttt cagatgattg agagggtgac
    11761 cgagcttgag ccgaatgttt cggcaacagg tataaaaaat gtgtcggtga acgagccgta
    11821 ttttgcaggt cattttcccg acacaccgat tatgccggga gtattgctca ttgaatctgc
    11881 ggcacagctt tgcagtcttg tatttgctcc cgaaagcgtt gaggaggaca agctgtatgt
    11941 tcttctaaaa gtcaaggatt tcaaaatgct ccgccccgtt attccgggtg acacgcttat
    12001 tatcagcgta aatgttacaa tgtcaacaaa gtcggcattt gaatttgcgt gtgtcatcaa
    12061 ggttgacggt gaagtgaggg caaagggaag tcttttgttt accacaatgg ataaaaatgc
    12121 ggtttacaag ccgtcacagg agtgattatg aaggttctcg tattaaacgg tagtccaaag
    12181 ggcgaaaaaa gcaatactct caacattaca aaagcatttc ttgacggctt ttcagccgat
    12241 acggaagttg aatatatcac ggttaaaaag gaaacaatca agccgtgtat gggttgcttt
    12301 tcgtgttgga gcagaacacc cggcaaatgt gttataaagg acgatatgca gaaaatctac
    12361 gaaaagatta attctgccga tattatcatt gagagctttc cgctctactt tttcggtatg
    12421 ccgtcacaga tgaaagcatt aaccgacaga tgtctgccgt atatgctccc ctattcggga
    12481 aatgttgccg aggacaaaga agcctctttc catgaactgc gtgatgaagc aatgcacgaa
    12541 aagaggcttg cggttattac aacttgcggc tatgtgagtg ccgaaccgat gtatcccgca
    12601 cttataaaac agcttgattt gatttgcggt aacggcaatt acacgatgat aaaatgcccc
    12661 gagggcgagc tttttattgc agaaaaagct gaaaggcaga gaaaggcata ccttgattca
    12721 atcacggagg caggcaggga attctgcgaa aaccgctgcc tttgcgatga aacaatgaaa
    12781 aaaatttcaa agcctattct ctcccccaaa gga
//
