LOCUS       c00029_gnlPro..        14948 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MBPGOLJE_29.
ACCESSION   c00029_gnlPro..
VERSION     c00029_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 21:06:53
            Original ID  :: gnl|Prokka|MBPGOLJE_29
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14948
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14948
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6193:10440]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      6194..10440
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..14948
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14948
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             complement(703..1065)
                     /locus_tag="ctg29_1"
                     /transl_table=11
                     /translation="VQFFEGKGYSDEFVCGMAKIVSVLENNNANLTLTGGCDEICSSCP
                     NRDNGSCDVTGKASCYDKRCLDLLGMKIGDTADWKELSRIARENIILKDRLSQVCGDCK
                     WSHICRDKADKMKSLH"
     CDS             complement(1091..1639)
                     /locus_tag="ctg29_2"
                     /transl_table=11
                     /translation="MTEAKTNSKSKSNVLSLVYMAMFVAIITVCAQIQIPMTVPFTLQT
                     LGIFMAAAMLGWKRGLISVAVYVLLGAIGVPVFAGFSGGIGVLGGPTGGYIIGFLFTAL
                     IVGLMTDFLGRKLWVLAVSMVAGLAVCYLFGTIWFMIAMHTDFVAALLTCVVPFLLADA
                     AKIVVATVLVNRLDKIVKL"
     CDS             complement(1910..2776)
                     /locus_tag="ctg29_3"
                     /transl_table=11
                     /translation="MPLVNAKEMLTKAKAGHYAVGQFNINNLEWTKSILLTAQELNSPV
                     ILGVSEGAGKYMCGYKTVVGMVNGMLEELNITVPVALHLDHGSYEGAKKCIEAGFSSIM
                     FDGSHYPIEENIEKTKELVATCNKLGLSLEAEVGAIGGEEDGVIGMGECADPKECKMVA
                     DLGVTMLAAGIGNIHGKYPANWKGLSFETLDAIQQLTGEMPLVLHGGTGIPADMIKKAI
                     SLGVSKINVNTECQLAFAAATRKYIEEGKDLEGKGFDPRKLLAPGAEAIKATVKEKMEL
                     FGSVNKA"
     CDS             3061..3186
                     /locus_tag="ctg29_4"
                     /transl_table=11
                     /translation="MIIFFVNYPVGVVLRPQVMTDILLQTKFYKYNKTTDIVTGG"
     CDS             3309..5048
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Trypsin_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1057:Trypsin-like peptidase (Score: 122; E-value:
                     1.3e-37)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg29_5"
                     /sec_met_domain="Trypsin_2 (E-value: 2.9e-38, bitscore:
                     122.0, seeds: 183, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNFDNNNMGGFEPQKPFTEKPVQNNNMNTEQTIPVSEPETQEEQ
                     AQNVQPQNGNTPYGDYIFGNNNQNTANNANPTENVPPYQQNQNPNPNTYAQPWQYGYGQ
                     YPYSGQNPQYNQNNQQYGQYQNNTGYNQNVPPYQQNMYGQPPYGNNGTYNQQYNPQMFA
                     QYPQKKTKGGIIALIIVLCSLLTIGFIGMMVYGFSADIKEDLNNDRSDSGNSFRLPNKD
                     STTPFETLPDTSSQGKTHDESDYSDKVNKDYSGMKLESNPKDAKTNNSYTAAKASEKVS
                     DSVVGILCYSDDVPDQADTTTASSQGSGIIFSQDGYVITNAHVIGNSKTAYAIRVVTSD
                     GKVYKAGVVGYDSRTDIAVLKMDDAKGLTPATFGDSSQLEVGQDIIVVGNPGGLDYQNT
                     TTKGVISALDRKLSTSSLTKYIQTDAAINPGNSGGPLVNYYGQVVGITTSKIVSETYEG
                     MGFAIPSQTVKSIVDTLVKNGYVEGRVKIGISGIAVTSDQASNYNIPQGIYVQSIVSGG
                     PCDGTSLKEGDIITEVDGETITSFADVYAILETHKPGDKIKVKYYSSSSGDGEVEITLQ
                     EDK"
     CDS             complement(5253..6050)
                     /locus_tag="ctg29_6"
                     /transl_table=11
                     /translation="MKKRLKGFFQRLARWLNVREMRQHKVKAGVYIIIRLILVSLLTAG
                     ILNGKWENVMTCVLTLGLLMLPLFIDRKLSVALPSVLETIVVLFVFAANVMGELGAFYE
                     KIPIWDSLLHTVNGFICAGVGFGLTDILNRSERVKLSLSPMFVCLFSFCFSMTVGVVWE
                     FFEFGADMLFEKDMQKDTVITAIHSGLISGKPNVIMHIRDITSTVVNGENLGINGYLDI
                     GLIDTMKDLLVNFVGAVVFDTIGWFYLKGRSAGFLRNFIPVKK"
     CDS             complement(6194..7537)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg29_7"
                     /sec_met_domain="HGD-D (E-value: 1.5e-27, bitscore: 87.0,
                     seeds: 370, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGNSVMAELKYDKKTGRLLFTKQMKKEYTILMPNMAPIHFKILE
                     KVFNYYGYKSDLLDTTGPEIAQTGLKYVHNDTCYPALLVIGQFINALQSGKYDVHKVAL
                     MITQTGGGCRASNYIFLLRKALKKAGFEFVPVISLSFGMEHNSGFSLTLPLIRRFVGGL
                     VYGDQLMLLSNQTKPYEVNKGESMALVDEWTDKISDMLIQGKGYTLEEIDETLDKITKS
                     FTKIELNKVPKVKVGIVGEIYVKYSKMANNGLEDFLADQDCEVCVPGLMGFASFKVDNR
                     IEDYKMFGGSRVKYKFCSMLLNYLTKLEGLMVDAAEKYGFVPPHRYAHTKELVNGVIGY
                     GSKMGEGWLLTAEMIELADTGYENIVCTQPFGCLPNHINGKGAIRKIKEIRPNANIVTI
                     DYDPGAPKVNQENRIKLMLAVGKEELKKKLEAEKNGEKAESSEKSEKK"
     CDS             complement(7537..10440)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg29_8"
                     /sec_met_domain="HGD-D (E-value: 5.6e-18, bitscore: 55.6,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 6e-39, bitscore:
                     123.9, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKLGLDIGSTTIKCVVLDDENKLIYSTYERHYSRITEKIAEILAL
                     VRTRIDGVENASVALSGSAGMGVAESVGVDFIQEVYATRVAANTFIPGTDVIIELGGED
                     AKILFLTNGLEVRMNGTCAGGTGAFIDQMATLLNVKLEDMDELAKQHEKTYTIASRCGV
                     FAKTDIQPLLNQGARKSDIAESIFNAVVSQTVAGLAQGREIEGQIVYLGGPLTFMSELR
                     NCFDRTLGTKGICPENSLYYVACGAALCAEKTIDFDEVIEKVKNYRGSGNFAFNQPLFK
                     NEEEYKEFCDRHAKADVKQKELKGYTGKAYIGMDAGSTTVKGVVLNDDGELLYSKYLPS
                     KGNPVEIMKQFLDEVYEINPEINVVSSAVTGYGEDIVKNAFAVDYGIVETIAHFTAAKY
                     FMPDVEFIIDIGGQDIKCFKIHNGAIDNIFLNEACSSGCGSFLQTFANALGYEIADFAK
                     LGLFAKRPVDLGSRCTVFMNSSVKQAQKDGATIEDISAGLSLSVVKNALYKVIRASSPD
                     ELGKRVVVQGGTFLNDAVLRAFEQEMGVEVVRPNIAGLMGAYGAALYAKKKSKGVGKST
                     ITDKKGLDEFVHEIKVANCGMCNNNCRLTINSFGKGRKFIAGNRCERPITKKAPANDMN
                     MYAYKLNLIDSYKPVEGIRGKLGIPMALNMYELYPFWYRFFTELKFEVFHSPYSTRKLY
                     QRGQQTIPSDTVCFPAKLVHGHIQTLIDMGAETIFYPCLSYNFDEHLGDNHYNCPVVAY
                     YPEVIKNNMKDIRKVHFIKEYFGIHRPNDFPKKAYERLSFHFPDLTLNEVRNAAKLAYQ
                     EQENYRKKVIDKGNEIIAKAEKEGKKIFVLAGRPYHIDPEINHGIDRLISGFDVAIVSE
                     DVISPRVEHFRTHVLNQWTYHARLYAAAKYVTTRKDMELVQLVSFGCGVDAITTDEVRE
                     ILESKNKIYTQIKIDEITNLGAVKIRIRSLLAALEND"
     CDS             complement(10726..11379)
                     /locus_tag="ctg29_9"
                     /transl_table=11
                     /translation="MCQSVCAKAVLKEKFTMTILDSVKGTVNTAVDTISSVAQTIVEKN
                     RTNAKLNRLRLVMKSESELMNRAYIALGKIMYDSRKKGTEINDAECEKLLKVIDTSKAK
                     IAKARECYRKIVNSSNDIFYGNPEVAPEVKEDDIVDITVACSNEGDYKSSPFKEEKPVE
                     KQPEAVTEEKAEPEHLTNICDLKAELEAKREEGFSESADSDEADDGEAPHGELF"
     CDS             11524..12222
                     /locus_tag="ctg29_10"
                     /transl_table=11
                     /translation="MPEKKITKAIVCPMCGEMSKADVYTSINPSVTKGVRRRALDGELF
                     AWKCPSCGYSARLTYPILYNDMKNRFMVYFIPKIDHFQLCDNELEEKYSNLRNISKRIV
                     PTFNSFKEKIFIFESGLDDMSVELTKLAISQTVSKKLNGAEIHDGYLSMYDRERNTMGF
                     TYFTGEKHTPYVQTARLEIYVKSKKIVDSLAYKDKKLKGFLKIDREWAENILYRYKRMK
                     HIEKLNKLKE"
     CDS             complement(12507..13511)
                     /locus_tag="ctg29_11"
                     /transl_table=11
                     /translation="MAVTFEGMERRMPKIEKCLAEYGIANLEEARKICNDLGFDPYDIV
                     KGVQPIAFENAGWAYTLGCAVAVKKGAKTASEAAEAIGIGLEAFCIPGSVAEQRNVGRG
                     HGNLGAMLLRDETKCFAFLAGHESFAAAEGAIGIARNANKARKEPLRVILNGLGKDAAY
                     IISRINGFTYVKTQFDYFTSELKIVEERAFSDGERAAVRCYGADDVREGVAIMQHENVG
                     VSITGNSTNPTRFQHLVAGTYKKWANENGVKYFSVASGGGTGRTLHPDNMGAGPASYGL
                     TDSMGRMHGDAQFAGSSSVPAHVEMMGLIGMGNNPMVGATVACAVAVYEAVNK"
     CDS             complement(13533..14225)
                     /locus_tag="ctg29_12"
                     /transl_table=11
                     /translation="MIYSKEVENMCTVAKGPKHGPAPIPEEGKWVKSYDIKDISGLSHG
                     IGWCAPQQGACKLTLNVKDGIVEEALVETIGCSGMTHSAAMAAEILPNKTLLECLNTDL
                     VCDAINTAMKNIFEQLVYGRSQTAFSEGGLPIGAGMEDLGKGLRSQVGTMYSTNAKGVR
                     YMEMAEGYVLKTALDENDEVIGYQFVKLGKMLEDIRHGVEPNEAYKNNIGQYGRFDGAA
                     KYIDPREE"
     CDS             complement(14439..14633)
                     /locus_tag="ctg29_13"
                     /transl_table=11
                     /translation="MKNLRLKSARAAKDLSQQQLAELVKVSRQTISAIEKGDYNPTINL
                     CIAICKALDKTLDELFWEE"
     CDS             complement(14630..14947)
                     /locus_tag="ctg29_14"
                     /transl_table=11
                     /translation="VLEINWAELSVQMFIGLFLSTAVFVGISILNDAYFTSNKGRRSLL
                     GSLAFVAGAECLGIAFGNKTFVTNGIANLDIIPIIVMIWTISIFVIVVIKKIIDKKAVE
                     E"
ORIGIN
        1 atacttaaag ttatacagtt taaataataa tccaatttcc tccaaaagtc aatattttca
       61 ttcgtgaaga tagtttttta agtcaaatac tttaatgccc gagcgttatt ttctatatta
      121 aggtaacttt gtagccgagt gcctcggcag tcaattcgtg aagacagttt gtacaataga
      181 aaactaaaaa tgcccgagcg tgactttcta tattaaggta gttttttcaa ccaagtgcct
      241 ctacagccaa ttcgtgaaaa tagtttgtac aatagaaaac taaaaatgcc cgagcgtgaa
      301 attgttattg tctgtaccaa cctgtagggg cgttcatcgg acgcccacag gtaacggcag
      361 aattttcata acagattaaa ttttataaat gccgcaaaac aattgttata ttgtaggggc
      421 gaaccgtgtg cattgcacac ggtttgcacg caatgcgtgc aaattcgata cacaacattt
      481 atcacatcaa aacatatgtg actaaacaaa atgtttcatc aaggcgggcg tccaatgaac
      541 gcccctacaa cacaaattgc aaaaacaatt acaaatattt gctcgggcaa aatatgtttt
      601 aaaatataca aactgtctgc acaaacaggg aacggcggct cgccgtaaac aaaagacctc
      661 acgaaattcg tgaggtcttt tatcatgata tatctatgag gattaatgaa gacttttcat
      721 tttatcggct ttatcacggc atatatgcga ccatttgcag tcgccgcaca cctgtgaaag
      781 cctgtctttt aaaattatat tttcccttgc aattctcgaa agctctttcc aatcggcagt
      841 atcgccgatt ttcattccga gtaaatcaag acatcttttg tcatagcatg acgccttgcc
      901 cgtaacatcg cagctgccgt tgtcacggtt cggacacgat gaacaaattt cgtcacaacc
      961 gcccgtaagt gtaaggtttg cgttgttatt ttcaagaacc gacactattt ttgccattcc
     1021 gcagacaaat tcatcgctgt aacccttgcc ttcaaaaaac tgcacacaaa ggctgtgatg
     1081 cggtctgaac ttaaagctta acgattttgt caagacgatt caccaaaact gttgcaacaa
     1141 caatctttgc agcatctgca agaaggaacg gaacaacgca ggtgagaagt gcggcaacaa
     1201 agtctgtatg cattgcaatc ataaaccaga ttgtaccgaa aagatagcat actgcaaggc
     1261 ctgcaaccat tgaaaccgca agcacccaaa gctttctgcc gagaaaatca gtcataagtc
     1321 caacgataag tgccgtaaag aggaaaccga tgatataacc gcctgtcgga ccgccgagaa
     1381 cgccgattcc gcctgagaat cctgcaaaca cgggaacacc gattgcaccg aggagaacat
     1441 aaaccgcaac gctgatgagt cctcttttcc aaccgagcat agccgcagcc ataaagatgc
     1501 cgagagtctg aagtgtgaac ggaactgtca tcggaatctg aatctgtgcg cacactgtga
     1561 tgattgcgac gaacatcgcc atatacacaa ggcttaatac attacttttt gatttactgt
     1621 ttgtttttgc ttctgtcata aaattacctc tcctttgcaa aaccgcttct tttgttttgc
     1681 agattgtcaa ccaaattatt ttatcggttg acaattatta tagtaccgat tatcgcattt
     1741 gtcaacccga tttatgtttt aaagtgacaa ttacaatccg ttttgatgta acaattgact
     1801 ttacaaccgt cttataatac aactgagtta accaaacaga acataaaaac agggacagca
     1861 ttttgctgtc cctgaaattt ttgtaaagat taagtttgcg tgcttacaat taagccttgt
     1921 taaccgaacc gaagagttcc atcttttcct taacagtagc cttgatagcc tctgcaccgg
     1981 gagcgaggag ctttcttgga tcgaagccct tgccttcgag atccttgccc tcttcaatgt
     2041 actttcttgt agctgctgca aatgcgagct ggcactctgt gttaacattg atctttgaaa
     2101 cgccgagtga gatagccttc ttgatcatgt cggcagggat acctgtaccg ccgtggagaa
     2161 cgagcggcat ctcgcctgta agctgctgga tagcgtcaag agtttcaaag ctgaggccct
     2221 tccagtttgc aggatactta ccgtgaatgt taccgatacc tgctgcgagc attgttacgc
     2281 cgaggtctgc aaccattttg cattccttag gatctgcgca ttcgcccatg ccgattacgc
     2341 cgtcttcctc gccgccgatt gcaccaacct cagcctcaag tgaaagaccg agcttgttac
     2401 aagttgcaac gagttccttt gttttttcaa tgttttcttc gatcggatag tgtgaaccgt
     2461 cgaacatgat tgagctgaaa ccggcttcga tgcacttctt agcgccttca tatgaaccgt
     2521 ggtcaaggtg gagagcaaca ggaactgtga tgttgagttc ctcgagcata ccgtttacca
     2581 taccaacgac tgttttgtag ccgcacatat atttaccggc accctcagat acaccgagga
     2641 taacaggtga gttgagttcc tgtgctgtta aaagaattga ttttgtccat tcaaggttgt
     2701 tgatgttgaa ctgacctact gcatagtggc ctgcctttgc ttttgtaagc atttctttag
     2761 cgtttactaa tggcatttta atcttccttt tttaaaaaat ttcagcagac aagcgtcccc
     2821 acctgccgat ttaagtttat tatacaatat atttttgaaa atataaagac ctaaaaagaa
     2881 gatttagtga aaattttaac aattagtcga aaaattcttc attttgtcct gttttagtca
     2941 attatcacta aactttcaaa ataaactcac acttccgtaa cacaacaagg ttgattttga
     3001 ttttgtgaaa aggtataata taaatgtaaa ttacaatact tgattttggt caagcgttgt
     3061 atgataatat tttttgtaaa ctatcccgta ggggtagtct tgcgaccgca agtaatgaca
     3121 gatattttat tgcaaacaaa gttttataaa tataacaaaa caaccgatat agtgactggc
     3181 ggatgatatc cgcccctacg aaatatttgt tcatttcggc aatttgcttg caaaaaattt
     3241 tgtttcatta cttaaggaca aacgcagttt gtaccccacg gtaacaaata aatgtaggag
     3301 taacttttat ggacaatttt gacaacaaca atatgggtgg gtttgaaccg caaaagccgt
     3361 tcaccgaaaa gcccgtacaa aacaataata tgaacacgga acagacaatt cccgtttccg
     3421 aacccgaaac acaggaagaa caggctcaga atgttcagcc gcagaacggc aacacaccgt
     3481 acggtgatta tattttcggc aacaacaatc aaaacacggc aaacaatgca aatccgactg
     3541 aaaatgttcc gccgtatcag cagaatcaaa atccgaatcc gaacacctac gctcagccgt
     3601 ggcagtacgg ttacggtcag tatccctaca gcggacagaa tccgcagtat aatcagaaca
     3661 atcagcagta cggacagtat caaaacaaca caggatacaa tcagaatgta cctccgtatc
     3721 agcagaatat gtacggacag cctccctatg gcaacaacgg tacatacaat cagcaataca
     3781 atccgcagat gttcgcacag tacccccaaa agaaaacaaa gggcggaata attgcgttga
     3841 ttatcgttct ctgttcactt cttacaatcg gttttatcgg catgatggtg tacggatttt
     3901 cggctgacat aaaagaagat ttgaacaacg accgaagtga ttcgggcaat tcgttcagac
     3961 ttccgaataa agacagcaca acaccgtttg aaacccttcc cgacacatct tcgcagggta
     4021 aaactcacga tgagtcggac tacagtgaca aggtgaacaa ggattactcg ggtatgaagc
     4081 ttgaaagcaa tccgaaagac gcaaaaacaa acaacagcta cacagccgca aaagcgtcag
     4141 aaaaggtttc cgactcggta gtcggcattc tctgttactc ggacgatgta cccgatcagg
     4201 ctgacacaac aaccgcatct tcacagggaa gcggaattat cttctcacag gacggctatg
     4261 ttatcacaaa cgctcatgta atcggcaaca gcaaaacagc ctatgcaatc agagttgtaa
     4321 catctgacgg caaggtatac aaggcaggtg ttgtaggtta cgattcaaga accgatattg
     4381 cagttctcaa aatggacgat gcaaagggac ttactcctgc aacattcggc gattcgtcac
     4441 agcttgaggt tggtcaggat attatcgtag tcggcaatcc cggcggtctt gactatcaga
     4501 acacaacaac caagggcgtt atttcggcgc ttgacagaaa actttcaaca tcaagcctta
     4561 caaagtacat tcagaccgat gccgcaatca atccgggcaa ctcgggcggt ccgcttgtaa
     4621 actactacgg tcaggttgtc ggaattacaa cttcaaagat tgtttccgaa acttacgaag
     4681 gtatgggctt tgcaattccg tcacagacag taaaaagcat tgttgacaca cttgtaaaga
     4741 acggctatgt tgaaggcaga gtaaaaatcg gcatttcggg cattgcagta acctccgatc
     4801 aggcatcaaa ttacaacatt ccgcagggca tttatgttca gagtatcgta tcgggcggtc
     4861 cgtgtgacgg cacaagcctt aaagaaggcg atatcatcac agaggttgac ggcgaaacaa
     4921 ttacaagctt tgcagatgtt tatgcgattc ttgaaaccca caagccgggg gacaaaatca
     4981 aggttaaata ttacagctca tcatcgggcg acggtgaggt tgaaatcaca cttcaggaag
     5041 ataagtaatt ttaatataag aatatcacca aaagcaagag ggcagtcacg gcaatgtgac
     5101 tgccctcttg ctaattgaaa attaaaagta aaaaattgca ggggtgaacc gtgttcgccc
     5161 gttcgtgtgc gatgcacacg attgaacgca tagcgttcaa atatcatatg caactcattt
     5221 atataattta attttgcata tacattgcgt cattattttt taacggggat aaaattccgc
     5281 aaaaatcctg cacttcttcc tttcaggtaa aaccaaccta tggtgtcaaa aactaccgct
     5341 cctacaaaat taacaagcaa atctttcatt gtatcgatca gaccgatgtc aaggtaaccg
     5401 ttaataccga gattttcacc gttcacaacg gttgatgtta tatctctgat gtgcattatc
     5461 acattcggct tgcccgaaat caaacccgaa tgtattgccg tgattacggt gtccttttgc
     5521 atatcctttt caaaaagcat atccgcacca aactcaaaaa actcccacac aacaccgact
     5581 gtcattgaaa agcagaacga aaacaggcac acaaacatgg gcgagaggct caatttcacc
     5641 cgctcgcttc tgttcaaaat atcggtcagt ccaaaaccaa cgcctgcaca gataaagccg
     5701 ttcacagtat ggagcaatga atcccatatc ggaatctttt cgtagaacgc accgagctca
     5761 cccataacat ttgccgcaaa cacgaacagc acaacaatcg tttcaagcac actcggcaac
     5821 gctaccgaca gctttcggtc gatgaacaac ggaagcatca acagtccgag cgttaacacg
     5881 caggtcatga cattctccca ttttccgttt aaaatgccgg cagtcaaaag tgacacaagt
     5941 atgagcctta taatgatgta aacgcctgcc ttaaccttgt gctgtcgcat ttcacgcaca
     6001 ttcagccacc gtgcaagcct ttgaaaaaat cctttaagtc gttttttcat aatatccccc
     6061 gatttttaca cttatttttt ccttaaaaac gagataaacc cctgtaaaat tgtattagct
     6121 ttttctgcct gatattaccg caaaataaaa aagccaccgc catctgcgat ggctcataag
     6181 cattgatatt aaattacttt ttctctgact tctctgacga ttcggctttt tcgccatttt
     6241 tttcagcctc aagctttttc ttgagttcct ctttgccgac agcaagcatc agcttgatac
     6301 ggttctcctg gttgaccttc ggagcacccg gatcatagtc gatggtaacg atattggcat
     6361 tcggtctgat ttctttaatc tttctgattg cgcccttacc gttgatatga ttcggcagac
     6421 aaccgaaagg ctgtgtgcat acgatattct catagcctgt atcggcaagt tcaatcatct
     6481 cggctgtcag caaccagccc tcacccatct tactgccgta gccgataaca ccgtttacaa
     6541 gctcctttgt gtgagcatat ctgtgaggcg gaacaaagcc gtacttttca gcggcatcaa
     6601 ccataagtcc ctcaagcttt gtgaggtagt taagaagcat cgaacagaat ttgtatttaa
     6661 ctctgcttcc tccgaacatc ttgtagtcct caatacggtt atcaacctta aatgatgcaa
     6721 aacccataag accgggtacg caaacctcgc aatcctgatc tgcaagaaag tcctcaagac
     6781 cgttgttagc cattttggag tattttacat agatttcgcc gacaataccg actttaacct
     6841 tcggcacttt gttaagctca atttttgtga atgactttgt aattttatca agagtttcgt
     6901 caatttcttc aagagtgtag cccttgccct gtatgagcat atcggaaatc ttatccgtcc
     6961 actcatcaac aagcgccata ctttcgccct tgttcacctc atagggcttt gtctggtttg
     7021 aaagcagcat taactggtcg ccgtacacaa gaccgccgac aaatctgcgg ataagcggaa
     7081 gtgtgagcga aaagccgctg ttgtgctcca taccgaacga aagtgaaatt acgggaacga
     7141 actcaaagcc tgcctttttg agagcctttc tcaaaaggaa aatgtagttt gacgcacgac
     7201 atccgccgcc tgtctgagta atcatcaggg caaccttgtg aacatcatac tttccgcttt
     7261 gcagagcatt gatgaactga cctataacca gcaaagccgg ataacaggta tcgttgtgaa
     7321 catatttaag acctgtctgc gcaatctccg gacccgttgt gtcgagcaaa tcagacttat
     7381 agccgtagta gttgaacacc ttttcaagta ttttaaaatg aataggcgcc atattgggca
     7441 taagaattgt gtattccttt ttcatctgct ttgtaaacag caaacgacct gtttttttgt
     7501 catacttcaa ctctgccata acagaatttc ctttcatcaa tcgttttcaa gcgcagcaag
     7561 caaactgcgg attcggattt taactgctcc gaggtttgta atttcatcta tcttaatctg
     7621 agtgtaaatc ttatttttgc tttcaagaat ttctcttacc tcatcggttg taatcgcatc
     7681 aacaccgcag ccgaaggata caagctgaac aagctccatg tcctttcttg ttgtaacata
     7741 ttttgccgcc gcataaagtc ttgcgtggta tgtccactgg ttgagaacat gagtccggaa
     7801 atgttcaact ctcggagaaa taacatcttc gctgacgatt gcaacatcaa agcctgagat
     7861 aagtctgtcg attccgtggt taatttcggg atcaatatga tatggtctgc ctgcaagaac
     7921 aaaaatcttt ttgccctctt tttcagcctt ggcaataatc tcgttgccct tgtcaataac
     7981 cttttttctg taattttcct gttcctgata tgcaagctta gccgcatttc ttacctcgtt
     8041 aagagtgagg tcggggaagt ggaacgaaag tctttcatag gctttcttag gaaaatcgtt
     8101 cgggcggtga ataccaaagt attcctttat gaagtgaacc ttgcgtatat ccttcatatt
     8161 gtttttgata acctcggggt agtaagcaac aacaggacag ttgtaatggt tatctccgag
     8221 atgctcgtca aaattatagg aaagacaggg gtagaaaatt gtttctgcac ccatatcaat
     8281 aagagtctga atgtgaccgt gaacaagctt tgcagggaag caaacggtat cgctcggaat
     8341 tgtctgctga cctctctgat aaagctttct tgttgaatac ggtgagtgga acacctcaaa
     8401 tttaagttct gtaaagaatc tgtaccagaa cggataaagc tcatacatat tgagcgccat
     8461 aggaattcca agcttacctc ttatgccttc aacaggcttg taggaatcaa tgagattcag
     8521 cttataggca tacatattca tatcgtttgc aggagctttc tttgtgattg gtctttcaca
     8581 acggtttccc gcaataaact ttctgccctt gccgaatgaa tttattgtaa gacggcagtt
     8641 gttgttgcac ataccgcagt ttgcaacctt gatttcgtga acgaattcat caagtccctt
     8701 tttgtcggta attgtactct tgccaacgcc ctttgacttt ttctttgcgt aaagagccgc
     8761 accgtaagca cccataagtc ctgcaatgtt aggacggaca acttcaacgc ccatttcctg
     8821 ttcaaatgca cgcaaaacag cgtcgttaag gaaagtaccg ccctgaacta caacacgctt
     8881 gccgagttcg tcggggcttg acgcacgaat aaccttgtaa agggcattct ttacaacgct
     8941 gagtgaaaga cctgccgaga tatcttcaat tgttgcgccg tctttctgag cctgcttaac
     9001 gcttgaattc atgaatacgg tacagcgtga gccgaggtca acgggacgct ttgcaaaaag
     9061 tccgagcttt gcaaagtcgg caatctcata tccgagagcg tttgcaaaag tctgcaaaaa
     9121 gcttccgcaa cccgatgaac aagcctcatt aaggaatata ttgtcaattg caccgttatg
     9181 tatcttaaag catttgatat cctgtccgcc gatatcgatg ataaattcaa catcgggcat
     9241 aaagtatttt gcggcggtaa agtgggcgat tgtttcaaca atgccgtaat caaccgcaaa
     9301 tgcgttcttt acaatgtcct caccgtaacc tgttacggca gaagaaacaa catttatttc
     9361 gggatttatt tcgtaaacct cgtcaaggaa ttgcttcata atctcaacgg ggtttccctt
     9421 tgatggcaga tattttgaat agagcagctc accgtcatca ttgagaacaa caccctttac
     9481 ggttgttgaa cctgcgtcca ttcctatata agccttgcct gtgtagccct ttagctcctt
     9541 ctgcttaaca tcagcctttg catgacggtc gcagaattcc ttgtactcct cttcgttttt
     9601 aaagagcggc tgattgaacg caaagttacc gctgccacgg tagttcttta ccttttcgat
     9661 aacctcgtca aaatcaatag tcttttcggc acacaaagcc gcaccgcagg caacataata
     9721 aagtgaattt tcggggcaga tgccctttgt tccgagcgtg cggtcaaagc agtttcgcag
     9781 ttcgctcata aatgtaagag gtccgccgag atatacaatc tgaccttcaa tttctctgcc
     9841 ctgtgcaaga cctgcaacag tctggcttac aaccgcattg aaaatactct ctgcgatgtc
     9901 gctcttcctc gcaccctgat taaggagcgg ctgaatatcg gtctttgcaa acacaccgca
     9961 tcttgatgcg attgtgtatg tcttttcgtg ctgttttgca agctcgtcca tatcctcaag
    10021 cttaacattc agaagtgttg ccatctggtc aataaacgca cccgtgccgc cggcgcaggt
    10081 accgttcatt cttacctcaa gtccgtttgt gagaaacaat atctttgcat cctcaccgcc
    10141 gagttcaatt ataacatctg tacccggaat aaaagtattg gcggcaactc ttgttgcgta
    10201 aacctcctga ataaaatcaa cgccgacaga ctcggcaaca cccattccgg cagaacccga
    10261 aagagccacc gaggcatttt caacgccgtc aatccttgtc cgtacaagtg caagaatttc
    10321 tgcaatcttt tccgtaattc gggaataatg cctttcatat gtgctgtata ttaatttgtt
    10381 ttcgtcgtca agcacaacac attttattgt tgttgagcca atatccaatc ctaatttcaa
    10441 cttgtgcctc cgaaatcaat acatagtaat ctcattgtgc atatctaatt aattatagta
    10501 ttttttgcca agaaaataat tctaattcag aatattttca cctttgatga attttaccat
    10561 ttttatcaca aaaattcaat acacataaag ggcataatgt ataatctact gcatataatt
    10621 tgccctcaaa agcaaagcgg agcattgttc cgactttaat atatcttaaa aatgcagaaa
    10681 aacctgccga aatcggcagg tctttagctt taagtattta aattatcaga aaagttcacc
    10741 gtgaggagct tcaccgtcat ctgcctcgtc tgaatctgcg gactcggaga atccttcttc
    10801 acgctttgcc tcaagctctg ccttgaggtc gcagatgttt gtaagatgct cgggttctgc
    10861 cttttcttcg gtaacagcct cgggctgttt ttcaacaggc ttttcctctt taaaaggaga
    10921 tgacttgtag tcgccctcat ttgagcaagc tactgtaata tcaacaatat catcctcttt
    10981 aacctcggga gcaacctcgg gattgccgta gaaaatatcg tttgagctgt tgacaatctt
    11041 tctgtaacac tctcttgctt ttgcgatttt ggcctttgaa gtgtcaataa ccttcaaaag
    11101 cttttcgcac tcggcgtcat taatttcagt gcctttcttt ctgctgtcgt acataatctt
    11161 tccgagagca atatatgctc tgttcataag ctcgctttcg cttttcataa caagtcttaa
    11221 tctgttgagc tttgcgtttg ttctgttctt ttctactatt gtctgagcta ccgatgaaat
    11281 tgtatcaacg gctgtattta ctgttccttt tacactgtca agtatcgtca tagtaaattt
    11341 ctcctttaaa accgctttgg cacaaacact ctgacacatt ctgccgtggc gaataatatt
    11401 aaacttattt ctattattat gacagatttt tttgataaaa tcaacatttt tttaaaattt
    11461 acttgttaaa atcacggtca attgctataa ttagtttcat agagtgttaa agaggtggtt
    11521 tggatgcctg aaaagaaaat taccaaggca atcgtctgcc caatgtgcgg tgaaatgagc
    11581 aaggctgatg tttacaccag catcaacccg tccgtaacaa agggtgtgcg cagaagagcg
    11641 cttgacggtg agctttttgc gtggaaatgt ccgtcatgcg gatactccgc aaggctcaca
    11701 tatccgattc tctacaatga tatgaagaat cgttttatgg tgtatttcat tcccaaaatt
    11761 gatcattttc agctctgcga caacgagctt gaagaaaaat acagcaatct ccgcaacata
    11821 agcaaacgaa ttgttccgac cttcaattcg ttcaaggaga aaatttttat ctttgagtcg
    11881 ggacttgacg atatgtcggt tgagcttaca aagcttgcaa tcagccaaac ggtttcaaaa
    11941 aagcttaacg gtgcggaaat tcatgacgga tacctttcaa tgtacgatcg tgaacgcaac
    12001 acaatgggat ttacatattt tacaggtgaa aagcatacgc cgtatgttca gacagcaaga
    12061 cttgaaattt atgttaaatc gaagaaaatt gtcgattcgc ttgcatataa ggacaaaaag
    12121 ttaaagggct ttcttaaaat tgaccgtgaa tgggcagaaa acattctcta ccgctacaag
    12181 cgcatgaagc atattgaaaa gcttaacaag ctgaaagagt aagctgttac tgtagtcagt
    12241 cgattctttt ggtttaaaaa agaatctgca aataagtaac atatacactg taaagaatat
    12301 ccgtaaacat aaactcgtta aagcaaacat gcataaaaat ttccgccatt acgattgggg
    12361 cggcggaatc attcagctta atattttttg tatttgcaat tccaacttgt taaaatgccg
    12421 atacaatcgg ggattttcgt tgcacaaaaa atcagggatc gactcaaaga gccgacccct
    12481 ttttaattta ttgaaaagat tggtaattac ttgttaacag cttcataaac tgcaactgcg
    12541 caagcaactg tagcaccaac catcgggttg ttacccatac cgataaggcc catcatttca
    12601 acatgagcag gaacagaaga tgaacctgcg aactgagcgt caccgtgcat tctgcccatt
    12661 gagtctgtaa gaccgtatga tgcaggacct gcacccatgt tatcggggtg aagtgtacgg
    12721 cctgtaccgc cgcctgatgc aaccgagaaa tacttaacgc cgttctcatt tgcccacttc
    12781 ttgtatgtac ctgcaacgag gtgctggaaa cgagtcgggt tagtagagtt acctgtgata
    12841 gatacaccta cattttcatg ctgcatgatt gcaacacctt cacgaacatc gtcagcgccg
    12901 tagcagcgaa ctgcagctct ttcaccgtct gagaaagctc tctcttcaac gattttaagc
    12961 tctgatgtga aatagtcaaa ctgagtcttt acatatgtaa agccgttgat tcttgaaata
    13021 atgtaagcag catccttgcc aagaccgtta aggataacac ggagcggctc ttttcttgct
    13081 ttgttagcgt tacgagcgat accgatagca ccctctgctg ctgcaaagct ttcgtgacct
    13141 gcgaggaatg caaagcactt tgtttcatct ctgaggagca ttgcgccgag gttaccgtga
    13201 ccacggccaa catttctctg ctcagctact gagccgggaa tacagaaagc ctcaagaccg
    13261 ataccgatag cttctgctgc ctctgaagca gtctttgcgc ccttcttaac tgcaactgca
    13321 caaccgagtg tgtaagccca gcctgcgttt tcaaatgcga tcggctgaac gccctttacg
    13381 atgtcgtagg gatcaaaacc gagatcgtta caaatttttc ttgcctcttc aagatttgca
    13441 ataccgtatt cggcaaggca cttctcaatt ttaggcattc ttctttccat accttcaaat
    13501 gttactgcca ttatggtgtc ctccttaccg aattattctt cacgagggtc aatgtactta
    13561 gctgcgccgt caaaacgacc gtactgaccg atgttgttct tgtatgcttc gtttggctca
    13621 acgccgtgac gaatgtcctc gagcattttg ccgagcttta cgaactgata gccgataact
    13681 tcatcgttct cgtcaagtgc tgtcttgaga acatagcctt cagccatttc catgtaacga
    13741 acgcccttag cgtttgtgct gtacattgta ccaacctggc tgcgaagacc cttaccgaga
    13801 tcctccatac ctgcgccgat tggaagaccg ccctctgaga aagctgtctg gcttctgccg
    13861 taaacgagct gctcgaagat gttcttcata gctgtgttga tagcgtcaca aacgaggtct
    13921 gtgttaagac actcaaggag tgttttgtta ggaagaattt ctgctgccat agctgcagag
    13981 tgagtcatac ccgaacaacc gattgtttca acaagagcct cttcaacgat accgtcttta
    14041 acattaagtg taagcttgca ggcaccctgc tgaggagcac accagccaat gccgtgtgaa
    14101 agacctgaaa tgtctttaat gtcataagat tttacccatt tgccctcttc gggaataggt
    14161 gcaggaccgt gcttaggtcc ctttgctaca gtgcacatat tttcaacttc ttttgaataa
    14221 atcatgtgta cttctccttt caataaattg tatgagtccg aaatcctcaa acacctatat
    14281 tatacggctt aacccgacat ttttcaagca tttttcgtta atttttacaa ttcccccaca
    14341 ttgtaatatt tgccgtggca attttccgtt tgattttgaa aaggtaaaaa taaaaacggc
    14401 aaccgtgaaa caaatcaccg attgccgtta aagtttactt attcttccca aaacaattcg
    14461 tcaagggttt tgtcaagcgc tttacatatt gctatgcaaa ggttaattgt gggattgtag
    14521 tcgccctttt caattgcgct tattgtctgt cttgacacct ttacaagttc cgcaagctgt
    14581 tgctgtgaca aatcctttgc ggcacgggcg ctttttaatc ttaaattctt cattcttcaa
    14641 ctgccttttt gtcaattatt tttttgatga caactatcac aaaaatactt attgtccaaa
    14701 tcattacaat gataggaata atgtcaagat ttgctattcc gtttgtaaca aaggttttgt
    14761 tgccgaaagc aattcccaaa cattctgctc ccgcaacaaa tgccaaagag cctaaaagac
    14821 tccttctgcc tttattcgat gtgaaatatg cgtcatttaa aatgcttatt ccgacgaata
    14881 cggcggttga aagaaacagt cctatgaaca tttgaacgct gagttcagcc caattaatct
    14941 ccaaaaca
//
