LOCUS       gnlProkkaNPMKDELJ_16   24508 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NPMKDELJ_16.
ACCESSION   gnlProkkaNPMKDELJ_16
VERSION     gnlProkkaNPMKDELJ_16
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 19:50:29
            Original ID  :: gnl|Prokka|NPMKDELJ_16
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 35718
            Orig. end    :: 60226
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24508
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14508]"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14508
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     cand_cluster    1..24508
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..24508
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="((LANC_like and (Lant_dehydr_N or Lant_dehydr_C))
                     and not (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             1261..2178
                     /gene_functions="transport (smcogs)
                     SMCOG1118:binding-protein-dependent transport systems
                     (Score: 356.8; E-value: 1.5e-108)"
                     /gene_kind="transport"
                     /locus_tag="ctg16_30"
                     /transl_table=11
                     /translation="MGPFLLKRLAQIIPVLFIISFVIFALVYIAGNPVALMLPDDASQE
                     EIDQLTASLGLDRPFIVQYGNYLLHLMQGDFGDSFRYNTSALPLVLERLPATLELAVAA
                     LTLAVCIAIPLGIWSATKQNSPLDLIAAGGAVLGKAMPNFWLGIMLILLFSVTLGWLPV
                     SGRGTFAHLLLPAITLATGIAAEMTRLLRSNMIEILSQDYIRTARSKGIRETLVVYKHA
                     LRNSLIPLVTITALQTSTVVGGTLITETVFSWPGIGQLLIQAVNTRDMAIVQACVFVIA
                     FLVIAMNLLADVLYRFLDPRIKYD"
     CDS             2195..3106
                     /gene_functions="transport (smcogs)
                     SMCOG1085:binding-protein-dependent transport systems
                     (Score: 308.4; E-value: 5.8e-94)"
                     /gene_kind="transport"
                     /locus_tag="ctg16_31"
                     /transl_table=11
                     /translation="MALQLERLPRIEKRRPHRAIKRWARLLLRSKTGTVGLAIVAAVIV
                     MAVFASLLAPYDPNEMNPANMLQPPVWVDGGTAAHILGTDNLGRDILSRVIYGSQISLL
                     VGIAAVAVAGFIGVTIGIVSGYYGGWVDSFFMRLVDSFLSIPNILFALVILSVFGPSVW
                     TLIIVLGVTNWVNYARLVRGEVLSLKEREFVKAARSIGVKNGMLMFRHLLPNVLPAFIV
                     ISTLSVATTIILEASLSFLGLGIQPPDVSWGGILSDGRDYLATSWWLATFPGLAITITV
                     LGIIFLGDWLRDVLDPRSQSRR"
     CDS             3119..4108
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 199; E-value:
                     1.5e-60)"
                     /gene_kind="transport"
                     /locus_tag="ctg16_32"
                     /transl_table=11
                     /translation="MEKEALLSVKGLRTEFYTEHGAIPSVNGVTFSIKRGETVAVVGES
                     GCGKSVTSLSIMGLISAPGKVVAGEIEFNGNDLTAISDSEYRKLRGNELSMIFQEPLTS
                     LNPLFTIGNQLSEVILLHQNVMKAEAKQQSINMLKKVGIPRAEQVYRSYPHALSGGMRQ
                     RVMIAIALACSPKLLIADEPTTALDVTIQAQILHLLRTLVKENGTAILLITHDLGVVAE
                     MADTVIVMYAGQVVEQTDVITLFEQPAHPYTVGLLASTPKIDEHQQTLPSIEGTVPTPD
                     TMPTGCRFSPRCPKAMARCKQEAPPMFEATKGHYVRCWLFDEKGGAAV"
     CDS             4105..5142
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 213.3; E-value:
                     6.5e-65)"
                     /gene_kind="transport"
                     /locus_tag="ctg16_33"
                     /transl_table=11
                     /translation="MSDVLLEAKGITKHFPVSEGVLKRKKALLRAVDGVDLTIYSGETL
                     GIVGESGCGKSTLGNVLMRLLEPTSGELTFDGSPFLTLRGEALRQKRADMQMVFQDPFS
                     SLNPRMKVIDIIAEPLKTHKKAQGKQLVERVYELLDIVGLDRSYAGRYPHEFSGGQRQR
                     IGIARAIALKPKLVICDEPVSALDVSIQAQILNLLARLQKEFQLTFLFIAHGLPAIKHI
                     SDRIAVMYLGKVVELADKDDLFNQPLHPYTAGLISAVPVTDPRKRHQRQRIIPEGDMPS
                     PVRPPSGCRFHTRCPYAQERCAVEEPVLVEKAAGHQVACHFPLMNRPGGAPDEHHWQNG
                     HAPLA"
     CDS             5102..6235
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1247:acetylornithine deacetylase (Score: 269.2;
                     E-value: 9.1e-82)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_34"
                     /transl_table=11
                     /translation="MNIIGKTDMLRLLETLVNIDSGSYYKTGVDAVGKKLIRAFEPLGF
                     KAAVYKQPTYGNHVLLQHVEATQPAILLLAHMDTVYPVGTVKERPFSIKGERAYGPGVI
                     DMKGSHVTAFAALKALCNANPHAAKNVALLLTSDEEIGAPTGRPLIEEHGKGKRALLVM
                     EPARKDGSLVTARRGGGRFTLDVSGKAAHAGVEPEKGRSAIAELAAKIIKLHALSDHDA
                     GISINAGLIEGGTSVNTVASRAKAQIDVRISKLNQAEPLEKRIRAICQQPWLDGTTITV
                     TGGVTRPPMERNRDTMELISLIKAIGTSMGLHVTETATGGSSDASFTSALGIPTIDGMG
                     PVGGNQHSEEEYLEIESLEERALLLAYTIEALSAKTK"
     CDS             complement(6711..8495)
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     262.3; E-value: 5.6e-80)"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 383.6; E-value:
                     2.8e-116)"
                     /gene_kind="transport"
                     /locus_tag="ctg16_35"
                     /transl_table=11
                     /translation="MGSTTERQVQLKEFVSLMHLYRPSLWLLGLALFLVLMETALSLAV
                     PLLTMNLVDITVESNFSGTTAALIAGVFIVQIILSGISMYMMIYIGQIMVAKLRKDLWH
                     KVLRLPVSFYDQNSSGETMSRITHDTNVIKNFFTDQLIPFLSGTIKILGSIIILFALNW
                     SITLLLLLIVPVSLAVLKPLGRKTYKVSKALQDETASFQGDLGRVLSDIRLVKSSIAED
                     PETSQGNNRIDQLLKHGLDTGKIMAIISPLMTTITLLVLVVVFGYGGIQVANGVLSAGT
                     LVAIVFYMFQIIPPISQMGHFFTQLQKAKGATERITYIMEEELESQSVSGVSYTHNQET
                     VARVNGIRFANVSFSYPNGNHILKNVSFTANAGEVTAIVGPSGAGKTTLFSLIERFYPP
                     SEGTIEYDNQPINYFDVHDWRQNIAYVAQDSPLMAGTIRYNLTYGHAEKSSDADIHVAL
                     EKANLSSFIASLPDGLETEVGERGILVSGGQRQRLAIARAILRNPQILLLDEATAHLDS
                     HSEFLVQEALNQLMLSRTTLVIAHRLSTVQHADKLVVVQSGEITGEGTHDELIEHHQFY
                     RELVDRQLYKKESPELIN"
     CDS             complement(8479..9393)
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 57.9; E-value: 2.8e-17)"
                     /gene_kind="other"
                     /locus_tag="ctg16_36"
                     /transl_table=11
                     /translation="MMDNRIGMEIRNLRKKLGMSQENISSSVVSQSAISKIENGKYVPN
                     LHVLEAIASKLGVPVDHFLTLTTCYNSEYIETTYEMIEQLSLNEEYEELNRLTAQLIDC
                     GEAVEFPNWFKDYIRIHHLFSEFQCKKKDAKTTLKKLKCMAGCLPFEQSIQTKFHLYLG
                     IIHSHMKKYSYSETLDYLQKSLASVEGIKGKNTYLHKKNLKIYILYQKAIIELNYHHYD
                     AALKDIGQGLQLSRNYACTAYVGQFLYYKGLCLEKKGVPFKNILKHYQEAHFFASFTNN
                     LPFKKLLSDKLSVRKEESYGFYN"
     CDS             9614..9871
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_b"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_37"
                     /sec_met_domain="TIGR03731 (E-value: 1.5e-17, bitscore:
                     56.6, seeds: 23, tool: rule-based-clusters)"
                     /sec_met_domain="mature_b (E-value: 3.3e-10, bitscore:
                     33.1, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALFILSELMTENDVSILLKCFLQLICAGVSLAKKIGEEYQMEKA
                     FDLDLEVVHTKAKDVEPDFTSVSFCTPGCGETGSFNSFCC"
     CDS             10001..13150
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155:Lantibiotic dehydratase domain protein (Score:
                     1046.6; E-value: 0.0)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_38"
                     /sec_met_domain="Lant_dehydr_N (E-value: 5.7e-187,
                     bitscore: 615.8, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 7.9e-15,
                     bitscore: 48.6, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 2.7e-39, bitscore:
                     128.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKSEQLLYEPVDTIMLRAPILSLSHDHQNASKDDIIPILKEYIE
                     RPEIKEALAVASPNLFQSLDKIHGDPRSKKTRNAVSSLLKFLIRMSSRPTPFGLFSGIA
                     IGELGDKTVGSLSDTKQHQKRARPDMEWLLGVVSKIEKNQTIARKLNVFFNDAVYETDD
                     RVYLHYFSNCGQLRSSVNQERKDNISIRKTVVVEFVQSVAKKPISISELMNQLQLTYTS
                     ASIDEIESFVWNLFQQEFLISELRPPIVNCAPLSYIIQILESIPEAKGIGAMLKGIEGD
                     IETYNQLPIGQGLDFFQALTAKMQDIHPSKQPLQVDLSLTCTEKVKINRSIGEQAANAA
                     EWLWRLSKNETGIAHLREYHVEFLEKYGINREIPLLDLLSDEKGLGAPPTYKYPPSTKS
                     VKPPQTKSTHRLLMEKYIQCLRENAKEISLTASDLQKLMDNDTDDVFAPNSGELFVEVL
                     ASSAEEIDKGNYQLAIGTNVGSQELGQTFGRFSDMIAIEENRHLMEEQKKIEETFTDVE
                     TEYVELSFLPQSGRASNVSITQSTRDLHTTIATNANGQNKKLLLEDILVGATLGRFYLK
                     SKKSNKRLVFTSNNMFNYENAPNCFRFLREVSLEDGKAIQGLNLGSLREFAFIPRITSG
                     KVILSPAIWKLNDQMEELSDFSAPLDQWIERFSTWMKKMQVPERVFMAYGDNRLYIHLK
                     NDNHLQELRSELRRRGRVQLQEMIGDYGEKQWVKSPLGRHNAELIVPFKKRPHVPAKPT
                     VMIKPVAEVPIECREKEPGTDWLYFKLYGPVHKQQKLISTQIRTLVAELENHKLINSWF
                     FIRYYDNEPHLRLRFHGDPKALLAGALPIFQKWYAAQRLAGNIKKVVIEPYEREIERYG
                     GLSLMPLMERYFEKDSLLTSDLLGLSSKQAFKEPLELVASMYVVYFLTEYGWHHERQLE
                     WISKWSEDPAYSKEFRPYRNDVLKWLDQEENWKALKEQKGFLFKLFSKNEAIIHELSHN
                     MDKTPMTNTEERVVGSLIHMHCNRLLGTDRDREKKAMAFVRQIIESQKHWNKTKGRPLN
                     V"
     CDS             13162..14508
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140:Lanthionine synthetase C family protein (Score:
                     427.5; E-value: 8.6e-130)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_39"
                     /sec_met_domain="LANC_like (E-value: 2.7e-84, bitscore:
                     276.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEKVVDDQEKQETKRIIARLTEKLNDPQKVEEIVMDKNNVTTIS
                     KVNPWDPVSLSHGFAGTILFFSELHKMYPEEKWDHVAHNHIVYASNYLKNGVHSISLFG
                     GITGFAFAVFNASENGTRYQNLLAKLDEVIRRVAENEIEEEKQRNGLGALPTFYDVIQG
                     YSGIGRYLLERRKDTPAFNGLIEAILRQFVEMTATITWEEHEVPGWYVTQENQFLEKDK
                     KIYPFGNFNLGLAHGIPGPLSFLSLCLLKGIEIPGQRQAITTIGNWLVRHAKSNSTGAP
                     VWAHRIGVKEAIANNYTVTDEREGWCYGNPGVARSLYLAGKALNHQPYQDMAVKCFLGI
                     KEKTLEELDLQSATFCHGKSGLLQIMVRMKNDLNINDFDKLIIQLENGIKGQYKDQHPL
                     GFKDFEIGSRTNELDKAGLLEGAAGVGLALLSMVRDDGDFFWDKAFLIS"
     CDS             14519..15091
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Flavoprotein"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_40"
                     /sec_met_domain="Flavoprotein (E-value: 8.7e-31, bitscore:
                     99.7, seeds: 143, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPEKEEKNILVGISGSISVINMPSYLAFFKHTYGHVKVIITEQAN
                     KLFPASSLSLFCDDIFQDHNETIDPNKSSHVGLARWADLFIVLPATANKIGQVANGLGM
                     DLLSSTILASTKPVLFCPNMNEAMWNNFFVKRNMALLEEGGHMIIPPVEKEAYEVASGS
                     IRKNFIIPDMYTIAQEMDKAMAVKEKS"
     CDS             15195..15917
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 187.7; E-value:
                     4.3e-57)"
                     /gene_kind="transport"
                     /locus_tag="ctg16_41"
                     /transl_table=11
                     /translation="MEKVIETKNLTKKVKGKPLVEEINLSIAKGEICGLIGPNGAGKTT
                     IMKLLTGLLIPTSGEVKLNQLDVHKQRKEAMRSVGAIIESPIFFEFMTGRGMLLNLARL
                     HGLNKQERQEKVAEALAIVGLGGRGDEKIRTYSLGMKQRLGIAQALLGNPEIVILDEPA
                     NGLDPMGMRELRELILQLNKERNITFLLSSHLLDELQKICSTLIIIKQGNVLFYGKQEE
                     IYNKAENNLEEIFIGMMS"
     CDS             15917..16741
                     /locus_tag="ctg16_42"
                     /transl_table=11
                     /translation="MRQLIISEFERLWSRWSIRLLVLTLPVLVIATGVYFRNHNRNISI
                     DAVDYATAINFPILSISEHLFITFNILLIFICAYVLTEEYQQKQIKLILLRAYSMSQIF
                     LSKFIVMATSLFICFFLYYVASFTVGQMMFETPERSILFGSEAVVTNGEMVLYALNYYG
                     IAFLTSLAALSLFCFIAIAMPSVNALLGSGICILFFFIVGPQLLEQSTAFAEGSNVSYV
                     VYASITKIQYTGISLLLSGGALSGWLIAVILFYLLVFLVGAYLIFTRRNYYA"
     CDS             16754..17521
                     /locus_tag="ctg16_43"
                     /transl_table=11
                     /translation="MKHLIASEFERLWRMRMIKILLLLLIGISFFSAHFLTWFDLGLYT
                     ADSETPLNAVNFPWFLLREVSFFVTLVIMPLFCVIVLNAPIKAKTYNLVLYRPFHRLEF
                     LLSKWGTLLLIAVFITAFIWLIGVVLGFFFYQVPDYVTFYGDLTRYSVLNGYIYSAKLY
                     FLFWAIMVAGIAIASVMSILAPNPIIAYFLLMIAYVVPIYFSNELSFFLMPTQSIFISL
                     SESNMPLLYMVLPLIALLGGGISSLLWVKQDFK"
     CDS             17542..18216
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 208; E-value: 2.2e-63)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg16_44"
                     /transl_table=11
                     /translation="MEHILIVDDEIQITSIVGELLHEEGYHTTVANDGMTAIKLIKEQD
                     FDLIILDIMMPYVNGLDVCRSVREFTDVPILFVTARTSINDQINGLNIGGDDYINKPFT
                     HEQLLARIKTHLRREKRKQQPTDELVYGKITLDRRTNELRYGETPLLLTNKEFKIMEML
                     MSNPKQVFSKDHLYETIWGVEATGQSHTVTEHIRNIRIRIHKVDPMANLIHTVWGVGYK
                     LE"
     CDS             18209..19633
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 147; E-value: 1.7e-44)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg16_45"
                     /transl_table=11
                     /translation="MNKKRTTIKQQIRLTIAKTILLSFFATIIVVLASWAIVMSIDDRY
                     YANYYESQVPKITDEVQSLNRELVDSQVLGAQQLEKAIPTPGMEYQVLDEQGTFLYGSF
                     SANVNTEDVHLLNKVNKSFLEDNTATTFIPIVDQNGSFAGSVVLQYKLESEVEALFNIF
                     FVCLFLTPFFFIMIFTYYYASKLGKNYYARIQKLIVATDLVRKQNLDFEIEADGNDEIT
                     KLSTSFNIMKQALQDSLYQQWNLEKNRSEFISSVSHDLKTPLTIMKANAQMLERKIKDD
                     RNKTYIANMIGEIERTENLVQELDTKMNDEESFFAIEIKTVEPGHFFKTEFAKYKDFVQ
                     NEGLEFHTSVLDYRKKANTIQIDVQKITQVIDNLISNSLRFAEPYDGHIDCHAECHDDY
                     VKVTVSDNGKGFTESDLHYVFQKFYQNNDSADPHKGLGLYIVKHIIEKHGGNVQAWNDK
                     GAVVSFQLPAVPKNSH"
     CDS             complement(19943..20611)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170:metallo-beta-lactamase family protein (Score:
                     79.9; E-value: 3.2e-24)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_46"
                     /transl_table=11
                     /translation="MNVIPVKTKGSNTYIIKDKRSIIVDTGGKGNVPRILNALQDEGIS
                     KDDISLIIITHAHIDHYGSVKELTKKIAAPVLIHKEDASDMEQGIISSLYGRNKFGKMI
                     LPFFETKTEEGYKADIVIDKNISLVPYGVSGEIISTPGHTNGSISVFLENKVAIIGDLL
                     MGGSLGGLINRTKPNLHYFVNNKHIEKKSIQSLQKQELHTIYVGHGGPLNMTQFSSMAF
                     "
     CDS             21221..22150
                     /locus_tag="ctg16_47"
                     /transl_table=11
                     /translation="MKNRISMCSIVLIASIVSGCSQSGSDEYIEVQPQKEQAPAFQYRL
                     QIDITPPEEGSASEIMNNLAVYLQEFDLGYEVKGNRDEDRYELDLELPRTAYLRQEPVQ
                     MSVTGGLLESESLYVKTEEWIAFDNEQGTYGFMLQTTPDVENTYLELSFKDVAYTPVDV
                     LERDEQYETLAKEAEATVNEGEIVFTVDGEQAADYFSKLIKTSLSYSFPGIVERSNDEI
                     EKKLTIGDVEVTTQIEEGVLQRESYRIPIEEDGGTWTVDIQIDYTDLAYVGEIGEIADY
                     EVLSKEAYNDYIVSEQQRDLEELINALN"
     CDS             complement(22212..23039)
                     /locus_tag="ctg16_48"
                     /transl_table=11
                     /translation="MNTLFLLFLLLTFFGLILGLIKPALVRFPTRKRVFAYGIPAFIIT
                     AFLFGNTLPSETAQSAQLDRSLEKIETLETSVQDKETEIEELTVALEEAEESLKESEEQ
                     LELVQADDSIEEQLEEAKLEWEEEFREQIEEELEERITAEISEDYEDKLAALDDKIKEK
                     EQTIEEKETAISKLEEEVASASTDSGNATATTETETAQSSESASTDSCGPGTVKINSAS
                     ESELQAIYEIGPDRAAQIIQLRPFSSYNDMKRIKGIGDARAEAIKNQGIVCFD"
ORIGIN
        1 acactcacag cagaagacgt gaaatttaca cttgaacgtg tcgctacaga tgaaacgctg
       61 caagaatatc cgaattatcg gcaaattaag gaagtcgaca ccatcgatga acggactttc
      121 cagatcatta cgcacgaacc tgagccatct ttgttgcacc gtttgtcacg acttgggtca
      181 ggcatcctgc cgaaacgcta cattgaagaa gaagggtggg accattttct cgcccatcca
      241 attgggacag gaccgtatga atttaaagaa tgggtccgtg attcacggat tgtgttgacg
      301 ccttatgacg attattttga agggccagta gaagagtggg atgaagtcgt cttccgcatt
      361 attccagaaa attcaacccg cgtatcggag ctgctgacag gcggagtcga tatcgccgtc
      421 aacatcccgc ctgctgattg ggaccgggtc aacggcaatg cagggacagc gatgaaatca
      481 gagacgtcca accggacgat gatgctaatt ctccgggcga cagacggcta cccgactgcc
      541 gatgtccgcg tccgcaaagc gcttaatttg gcaattgaca acggggcgat tacggacagc
      601 gccttgcgcg gggcagggac gccgactaaa acgcgcgtag cgccaggcaa ttttggtgcg
      661 gaggaatctt tgtatgatac gtatgactat gatcctgaag aagcaaagcg tctccttgaa
      721 gaagctggtt atggcgatgg atttgaaatg acgctccatt cccctagggg gcgctatttg
      781 caagatgctg aaatagccga gttgattggc ggcatgctgc aagcgatcaa tgtcagcgtc
      841 aatgtcgagc tgatggaatg gagcaatttc gtcgaaatgc gccaagcagg cgccaataaa
      901 gatgcttatt tgatcggctt aggaaattca atgtttgacg gcgcttacag tgtcgactgg
      961 taccgctctg atcgttttgt cggccaaact gactataaaa ataaagagat agacgcattg
     1021 ctcgaagctt cggctgtcaa tatggaccaa accgaacggg ctgagcaact gaaagaaatc
     1081 cagcgcattg ccgatgaaga gctgccccat ataatgcttc atcaagagac cgtcaattat
     1141 ggtgtcaatg atcggattga ttttgtccca aaaatggatg aaatgatcta cgcacctgaa
     1201 attaagagaa aataaaaacg acggccgggg gaacctggcc tttgcaaagg aggcgagcca
     1261 atgggccctt ttttactgaa gcgcttggca caaatcattc cagtgctatt cattatttcg
     1321 tttgtcattt tcgcgctcgt ctacatagcc ggcaaccctg tagcgctcat gttgccggat
     1381 gatgcgtccc aagaggagat agaccaattg acggcctcgc ttggtttaga taggccgttt
     1441 attgtccagt acggcaacta tctccttcat cttatgcaag gtgattttgg tgattcattc
     1501 cgctacaaca caagcgcatt gcctcttgtg cttgagcggc ttcctgcgac gttggaacta
     1561 gctgtcgccg ctttaacgct agctgtatgt attgcgattc cactcgggat ttggtcggcg
     1621 accaagcaaa actcaccgtt agacttgata gcagcaggtg gggcagtgct tggcaaagcg
     1681 atgcctaatt tttggcttgg catcatgttg atcttgcttt tttccgttac actcggctgg
     1741 ttgcctgttt caggaagagg gacgttcgcc catttactat tgcctgccat cacactggca
     1801 acagggatag cggcagaaat gacgaggctg ctccgttcga acatgattga aattttaagc
     1861 caagattata ttcgcaccgc cagaagcaaa ggaatccgtg aaacgttggt cgtttacaag
     1921 catgcccttc gcaactcgct cattccactc gtcacgatca ctgctttgca aacatcgact
     1981 gtggtcggcg gtacattgat tacagaaacg gtcttctcgt ggccaggaat cgggcagttg
     2041 ctcatccaag ccgtcaatac gagagacatg gcgattgtac aagcatgcgt gttcgtgatc
     2101 gcctttcttg tgatcgcaat gaatttgctt gcagacgtgc tttaccggtt ccttgatcca
     2161 cggattaaat acgactagga gggaaatcaa accgatggca ttgcaattgg aacggctccc
     2221 gagaatcgag aaacgacgtc cccatcgcgc cataaaacgg tgggcacggc tcctgctccg
     2281 cagcaaaacc gggactgtcg gattggcgat tgtcgccgct gttatcgtga tggccgtatt
     2341 tgccagcctc ttggcgccct acgatcctaa cgaaatgaac ccggccaaca tgcttcagcc
     2401 gcctgtttgg gttgatgggg gaacagctgc ccatattctt gggactgata atttagggcg
     2461 cgatatttta agccgcgtca tttacggttc gcaaatttcg cttcttgtcg ggattgccgc
     2521 tgtcgccgtc gctggtttca tcggcgtgac gattggcatc gtttccggct attatggagg
     2581 ctgggttgat tcgtttttta tgcgccttgt cgactcgttt ttgtctattc cgaacatctt
     2641 atttgccctt gttattttaa gcgtgttcgg tccgagtgtg tggacattga ttatcgtcct
     2701 tggcgttacc aattgggtaa actacgcccg ccttgtccgc ggggaagtac tgtcgttaaa
     2761 agaaagggaa tttgtgaaag ccgcccgctc gattggcgtt aaaaatggca tgctcatgtt
     2821 tcgccatttg ttgccgaatg tgctgcctgc cttcattgtc atttcaacgc tcagtgtagc
     2881 gacgacgatt attcttgaag cgtcgctcag ttttttaggc cttggcatcc aaccgcctga
     2941 cgtgtcttgg ggcggaattt tgagcgatgg gcgtgattat ttggctacga gctggtggtt
     3001 ggcaactttt ccaggcttag caatcacgat tacagtgctt ggcattattt tcttaggtga
     3061 ttggttgcgt gatgtgctcg atccacgtag ccaaagccgg cggtaaggag aggatcagat
     3121 ggaaaaagaa gcgctcttgt cagtgaaagg gcttaggacc gagttttata cagaacatgg
     3181 cgcgatcccg tcggtaaatg gtgttacatt ctccattaaa cgaggggaaa cagtggcagt
     3241 cgtcggcgag tcgggctgcg gaaaaagcgt aacatcgctc tcgatcatgg ggctcattag
     3301 cgctccagga aaagtcgttg ctggcgaaat tgaatttaac ggcaacgact tgacggcgat
     3361 cagcgacagc gagtaccgca agctgcgtgg aaatgaactg tcgatgattt tccaagagcc
     3421 cctcacatcg ttaaacccgt tatttacaat cggcaaccaa ctgtcggaag tgattttgct
     3481 tcaccaaaac gtaatgaaag cagaggccaa gcaacaaagc atcaatatgc ttaaaaaagt
     3541 cggcattcct agagcggaac aagtttatcg ttcttacccc catgctttaa gcggcggcat
     3601 gcgccaacgt gtgatgattg ccattgccct agcttgtagc ccgaaactgc tcattgccga
     3661 tgagccgacg actgcgcttg atgtcacgat tcaagcacaa attttgcact tgctgcggac
     3721 gcttgtgaag gaaaatggca cagcgatttt gctcattacc catgatcttg gcgtcgtcgc
     3781 tgaaatggcc gacacagtga tcgtcatgta cgctggacaa gtagtcgaac aaaccgatgt
     3841 catcacgctt tttgaacaac cagcacatcc gtatacggtc gggctgttgg caagcacgcc
     3901 gaaaatcgac gaacaccaac aaacgttgcc ctcgatcgaa ggcacagtgc cgacaccaga
     3961 cacgatgcca acaggctgcc gcttttcgcc ccgttgccca aaggcgatgg ctcgctgtaa
     4021 acaggaagca cctccgatgt tcgaagcaac aaagggccac tatgtccgtt gctggttgtt
     4081 tgatgagaag ggaggggcgg ctgtatgagc gatgtattat tggaagcaaa gggaattacg
     4141 aagcattttc cagttagcga aggcgtcctc aaacgaaaaa aagcgctgct ccgcgccgta
     4201 gacggtgtcg atttaacgat ttattcaggg gaaacactcg gtattgttgg tgaatctggc
     4261 tgtggcaagt ccacattagg gaatgtcttg atgcggttgc ttgaaccaac aagcggcgaa
     4321 ttgacatttg acggcagccc gtttttaacg ttaaggggag aagcattgcg gcaaaagcgg
     4381 gccgatatgc aaatggtttt ccaagatccg ttctcttctt taaatccacg gatgaaagta
     4441 atcgacatta ttgccgaacc gttaaagaca cataaaaaag cacaaggcaa acagttggtt
     4501 gaacgtgttt atgaattgct tgacattgtt ggattggatc gttcctatgc agggcgctat
     4561 ccccatgaat ttagcggcgg acagcgccag cgaattggca tcgcccgagc gattgccttg
     4621 aaaccgaagc tagtgatttg cgatgagccc gtgtcggcac tggatgtctc gatccaagca
     4681 caaattttaa atttgctggc gcggctgcaa aaagaatttc aattaacatt tctgtttatt
     4741 gcccatgggc tcccggcgat caagcatatt agcgaccgta tcgctgttat gtatttaggc
     4801 aaagtcgtcg agcttgccga taaagatgat ttatttaatc agccgctcca cccatataca
     4861 gcaggcttaa ttagcgccgt gccggtcact gacccacgaa agcgccatca acgacagcga
     4921 atcattcctg aaggcgatat gccaagcccc gttcgtccac cgagcggctg ccgcttccat
     4981 acacgctgcc cgtatgccca ggaacgttgc gctgtcgagg aacctgtatt agttgaaaaa
     5041 gcggctggcc atcaagtcgc ttgccatttt ccattaatga atcggccagg aggtgcgcca
     5101 gatgaacatc attggcaaaa cggacatgct ccgcttgctt gaaacactcg taaacattga
     5161 tagcggctcg tactataaaa caggggtgga cgctgtcggt aaaaaattaa tccgcgcttt
     5221 tgaaccatta gggtttaaag cagctgtgta caaacagcca acctatggaa accacgtatt
     5281 attgcaacat gtggaagcaa cgcaaccagc gattttgtta ttggcccaca tggacaccgt
     5341 ctatccggtc ggcaccgtca aagaaaggcc gttttccatt aaaggagaac gagcgtatgg
     5401 gccaggggtg attgacatga aaggcagcca cgtcaccgct ttcgcagcac taaaggcact
     5461 gtgtaacgcc aacccgcatg cagcgaaaaa cgtcgccctt ttgctgacga gcgatgaaga
     5521 aattggcgcc cctacaggca ggccgctcat tgaagaacat ggaaaaggaa aaagagcctt
     5581 gctcgttatg gaaccagcga gaaaagatgg ctcccttgtc accgcaagga gaggcggcgg
     5641 acggtttaca ttagatgtca gcggcaaagc agcccatgcc ggtgtcgagc cggaaaaagg
     5701 ccgcagcgcc attgctgagt tagccgctaa aataatcaaa ctgcacgccc tctctgacca
     5761 cgacgcaggc attagcatta acgctggcct cattgaaggc ggcacatccg tcaacaccgt
     5821 tgccagccgt gcaaaagcgc aaatcgatgt ccgcatttcg aagctgaacc aagcagaacc
     5881 gttggagaag cgcattcgcg ccatttgcca acaaccatgg cttgacggca ccaccattac
     5941 agtaacaggc ggagtaacac ggccaccaat ggaacggaat cgcgacacga tggaactcat
     6001 ttccctcata aaagccattg gcacctcaat gggcttacat gtaacagaaa cagcaacagg
     6061 cggcagttcc gacgcttcct tcacatcggc cctcggcatt ccgaccattg acggcatggg
     6121 cccagtcggg ggaaaccaac atagcgaaga agaatatttg gaaatcgaat cgctcgaaga
     6181 acgtgccctg ctgttggctt acacaatcga agcgttgtca gctaaaacga aataggaaca
     6241 gcaaataacg caagcgtcac agccattgcg acgtttgcgt tttactattt catgttctcg
     6301 tcaaaaaaga gagaaaccag acagcatgat gctgctcatc cgtaggactg cgcgaaaaaa
     6361 gaaagggagc tgaccaataa gtcagctcat tttatagtag gttatcgtct atatcttcaa
     6421 gctcaatagg ttagctattc taagcttgaa tgaacaaagc gataatcaac aggatagaga
     6481 aaagcagaaa ggcgccattt aaaatgagcc caatcatttt gacagatggt ttggcggctt
     6541 tcaacgcgaa caagattcca acaatagaga gcaatgtcca caagccaatc gtatatgtcg
     6601 gctcaaattg aaaaagagtg cttacataat acaaaagaac gcttaaacaa aacaagataa
     6661 tggataacac aaatcttcac tactttcctt taaaagtcta gcgtgctctt ttagttgatc
     6721 aactcgggag attctttctt atataattgg cgatcgacaa gttcacgata aaattggtgg
     6781 tgctcgatta actcatcgtg tgttccttcg cctgttattt ccccgctctg gacaacgacc
     6841 aatttgtctg catgctgcac ggtcgacaat cgatgggcaa ttactagcgt tgtcctagaa
     6901 agcatgagtt gattgagcgc ttcttgtact aaaaattccg aatggctgtc aagatgggcg
     6961 gtggcctcgt ctaacaataa aatttgcgga tttcgtaaaa tggcccgagc gatcgcaagc
     7021 ctttgtcttt gcccgccaga tactaaaatg cccctttcac ccacttctgt ttctaagccg
     7081 tctggcaaag aggcaataaa tgaagataaa tttgcttttt ctaaggctac gtgaatgtcg
     7141 gcatcgctgc ttttttcagc atggccatac gtaagattgt agcgaatcgt acccgccatt
     7201 agcggagaat cttgggcaac ataggcaatg ttttgtctcc aatcatggac atcaaagtaa
     7261 ttgattggtt gattatcgta ctctatcgtc ccttcgcttg gtggataaaa tcgttcaatt
     7321 aatgaaaata aggtggtttt gcctgcaccg ctaggcccga caattgccgt tacttcaccg
     7381 gcattagcgg tgaaacttac atttttcagg atatggttgc cattcggata ggagaaagac
     7441 acattggcaa atcgaatgcc gtttacgcgg gcaactgttt cttgattgtg tgtataagat
     7501 acacctgaca ccgattgaga ttccaattcc tcctccataa tatatgtgat ccgttctgtt
     7561 gcgccttttg ctttttgcaa ttgcgtaaaa aagtggccca tttgtgagat tggagggata
     7621 atctggaaca tgtaaaaaac aatcgcaact aatgtgccgg ccgataagac cccattggca
     7681 acttgtatcc ccccgtaacc aaagacgacg actaatacta acaaggtaat ggttgtcatc
     7741 aatggagaaa taatggccat tatttttccg gtgtccaatc catgttttaa cagttgatcg
     7801 attctgttgt tgccctgaga cgtttccggg tcttccgcta tagacgattt gactaacctg
     7861 atatccgaca acacacgccc taaatcccct tgaaatgaag ctgtctcatc ttgcaacgct
     7921 ttcgacactt tgtatgtttt tctacctagt ggttttaata cagctagcga cacagggaca
     7981 atcaataata agagaagcgt aatgctccaa tttaatgcaa acaggataat aatcgaacca
     8041 agtattttaa tcgttcccga taaaaaagga atcaattggt cggtaaaaaa atttttaata
     8101 acatttgtgt catgggtaat tctgctcatt gtttctccag agctattctg gtcataaaat
     8161 gagactggca atcgtaacac tttgtgccaa agatctttac gtaattttgc caccattatc
     8221 tggccaatgt agatcatcat atacatagag atgcctgaca gaatgatttg cacgataaag
     8281 acgcctgcga ttagggcagc ggttgtgccg ctgaaatttg attcaacggt tatgtccaca
     8341 aggttcattg ttaatagggg gacagcaaga gatagcgccg tctccatcag gactaagaac
     8401 agagctagcc caagtagcca tagtgagggg cggtaaagat gcatcaggga aacgaactct
     8461 tttaattgaa cctgtcgttc agttgtagaa cccatatgat tcttcctttc tgaccgagag
     8521 tttgtctgat agcagttttt tgaaaggcaa attatttgta aagctagcaa aaaaatgggc
     8581 ttcctggtag tgctttaaaa tgtttttgaa gggaacgcct tttttttcta aacaaagacc
     8641 tttataataa agaaattgcc cgacatacgc cgtacaagca taattcctag ataattgcag
     8701 gccttgtcct atatctttta aagcagcatc atagtgatgg tagttcagtt caatgattgc
     8761 tttttggtac aaaatataga tttttaagtt ttttttgtgc aaataggtgt tctttccttt
     8821 aattccttca acggatgcaa ggcttttttg taagtagtct aacgtttcgc tatatgaata
     8881 ttttttcatg tgggaatgga taatgcctaa atataaatgg aactttgttt gaatagactg
     8941 ttcaaatggc aaacagccag ccatgcattt taatttcttt aatgtggtct tagcatcctt
     9001 tttcttgcat tggaattcag agaatagatg atggatcctt atataatcct taaaccaatt
     9061 agggaattcc accgcctcgc cacagtcaat taattgtgca gttagcctgt tcagttcctc
     9121 gtactcttca tttaacgaga gttgctcaat catttcataa gtggtttcga tgtattcact
     9181 attgtagcac gtggtgagcg ttaaaaaatg gtcgacaggc acccctagct tagaagcaat
     9241 ggcttcaagc acgtgtaagt ttgggacgta ctttccattt tcaattttgc ttattgccga
     9301 ttggctgaca acgctagagc taatattttc ttgcgacatg ccaagtttct ttcttaagtt
     9361 ccggatctcc atgccaattc gattatccat catatgcatc ttccttatca taacctgtat
     9421 tagttggttt ttttaagtga ggatgttatc gaaagattat caggcattta tcagaaatat
     9481 atcagattaa ccaaatctca acatttattt tccaaaaaaa tggggtctat agtaatgaca
     9541 ttttcaaaaa acaaacaaag ttattctaat tgtcataatt tataagagat actgtcaaaa
     9601 aacaagctca accttggcat tgttcatttt aagcgaatta atgactgaaa acgatgtttc
     9661 cattttgcta aaatgttttt tacagttaat ttgcgccggg gtttccctgg caaaaaaaat
     9721 aggggaggaa tatcaaatgg aaaaagcatt tgacttggat ttggaagtag tacacacgaa
     9781 agcgaaggat gtagaaccag atttcacaag cgttagtttc tgtactcctg gttgcgggga
     9841 aacaggtagc tttaatagct tctgctgcta agaaaaaagg cttttgatca tttacatggg
     9901 attgcccctc aaaaatcttg tatttttcta aaatacagat ttataaaatt gagcaagggc
     9961 aatcctgttt gtttttcatt tgaaagggga gttcatggcg atgagaaaaa gcgaacaatt
    10021 attatatgag cctgtagaca caatcatgtt gagagcaccg attttgtcat tatcgcatga
    10081 ccatcaaaac gcgtcaaaag acgatattat ccccattttg aaagaataca tagaacggcc
    10141 tgaaataaaa gaagcactag cggttgccag ccctaattta tttcagtctt tagataaaat
    10201 tcatggcgat ccccgttcca aaaaaacgag gaacgctgtt tccagcttgt taaagttttt
    10261 aataaggatg tctagccgtc caactccttt tggtttgttt tcaggcatag ctataggcga
    10321 acttggcgat aagacagtgg gatctttatc tgacacgaag caacaccaaa agagagcgcg
    10381 tccagatatg gagtggttgc ttggcgtagt tagcaaaata gaaaaaaacc aaacgatcgc
    10441 tagaaagctt aatgtttttt ttaatgatgc tgtgtatgag acggacgatc gagtctacct
    10501 tcattatttt tctaactgtg ggcagttaag aagcagtgta aatcaagagc gcaaagacaa
    10561 tatttccatc agaaaaacgg tggtggtaga gtttgtccaa tcagtagcga aaaaaccgat
    10621 ttcaatttct gaattaatga accagcttca attaacatat acgagcgcct ctatagacga
    10681 aattgaatcg tttgtttgga atttattcca acaagaattt cttatcagtg aattaaggcc
    10741 gccaatcgtt aactgcgcgc ctttatccta tatcatacag atccttgagt ccatccccga
    10801 agcgaaggga ataggggcga tgttaaaagg aattgaaggc gatatagaaa cgtataacca
    10861 attgcctatc ggacagggat tggatttctt tcaagcgcta acggctaaaa tgcaagacat
    10921 tcatcctagc aaacagccgt tgcaagtgga cctgagctta acatgtacag aaaaggttaa
    10981 gataaatcgt tcaattggcg aacaagcggc caatgcggca gagtggctgt ggaggctttc
    11041 aaaaaatgag actggaatcg cccatttacg ggaataccat gttgaatttc ttgagaaata
    11101 tgggataaat cgagaaattc ctctgctaga cttgttaagc gatgagaaag gtttaggggc
    11161 accgccaacc tataaatacc caccttcaac aaaaagtgtt aaaccgcctc aaacgaagag
    11221 cactcatcgt ttgttaatgg aaaaatacat ccagtgttta agggagaatg cgaaggaaat
    11281 atcattgacc gcctctgacc tgcaaaagct aatggataac gacacagatg acgtttttgc
    11341 tccgaattca ggggaattat ttgttgaagt gcttgcttca tcagcagagg aaattgataa
    11401 aggcaactat cagttggcaa taggaaccaa tgttggttcc caagagctag gccaaacatt
    11461 cggccgtttc tcggacatga tcgctatcga agagaatagg cacttgatgg aagaacaaaa
    11521 gaaaatagaa gaaacgttta cggatgttga aaccgaatac gtagagttga gttttctgcc
    11581 ccaaagtggc cgtgcaagca acgtttccat tacgcaatcc acacgggatt tacatacaac
    11641 cattgccacc aatgcaaacg gccaaaacaa aaagctgttg ttagaagata tattagttgg
    11701 ggcgacactt gggaggttct atttaaaatc gaagaaatca aataaacgtc tcgtatttac
    11761 atcaaataac atgtttaatt acgagaatgc accaaattgt ttccggtttt taagggaggt
    11821 ttctttagaa gatggaaagg cgattcaagg gttgaatttg ggaagcctta gagagtttgc
    11881 ttttattcct agaattacgt ctggaaaagt cattctctcg ccggcaattt ggaaattaaa
    11941 cgatcaaatg gaagaactgt ctgatttctc tgcgccactt gatcaatgga ttgagcgatt
    12001 ttcaacatgg atgaaaaaaa tgcaggtacc agaacgggtc tttatggctt atggggataa
    12061 ccgattgtac atccacttaa aaaacgacaa ccatttgcaa gaattaaggt cggaactaag
    12121 gcgcagagga agggtgcagt tacaagaaat gatcggcgat tatggggaga agcagtgggt
    12181 aaaaagccct ttaggcagac ataacgccga attaattgtt ccattcaaga aaaggcctca
    12241 tgtgccagca aaaccgacgg tgatgattaa gccagttgca gaagtgccaa ttgaatgcag
    12301 agaaaaagaa cctgggacag actggctcta ttttaagctt tatgggcctg tccacaagca
    12361 gcaaaaactg atttctacac aaattcgaac gcttgtagcc gagttagaga accacaaact
    12421 cataaatagc tggttcttta ttcgctatta tgacaatgag ccccatttgc ggctaaggtt
    12481 tcacggagat ccgaaagctt tgttggctgg cgcactgccg atatttcaaa aatggtatgc
    12541 agcccagcgt cttgcgggga acattaaaaa agttgtgatt gagccgtatg aacgggaaat
    12601 tgaacgatac ggcggccttt cgctcatgcc tctaatggag cgatactttg aaaaagatag
    12661 tttgttgaca tccgatttgc ttggtttaag tagtaagcaa gcattcaaag aaccgctaga
    12721 attagtcgcg tctatgtatg ttgtttactt tttaacggaa tacggttggc accatgaaag
    12781 gcaattggag tggatttcca agtggagcga agatccagct tactccaaag agtttaggcc
    12841 ttatcggaac gatgtgctta aatggctaga ccaagaagaa aactggaagg ctctaaagga
    12901 gcagaaaggc tttctcttta agctgttttc caaaaacgaa gcaatcatac acgagctttc
    12961 ccataatatg gacaagacgc cgatgacaaa tacagaggaa agagttgtcg ggagcttgat
    13021 ccatatgcat tgcaaccggt tgctcggcac agaccgtgat agggagaaaa aagcaatggc
    13081 gtttgtgcgc caaattattg aaagtcaaaa gcattggaac aaaacgaaag ggcgaccatt
    13141 aaacgtatga ggtgatccac cgtgatagag aaggtagttg atgaccaaga aaaacaagaa
    13201 acgaaacgaa ttattgcccg tttgaccgag aaactaaacg atccacaaaa agtggaagag
    13261 attgtaatgg ataagaacaa tgtcacgacg attagcaaag taaatccgtg ggaccctgtt
    13321 tctttatctc atggttttgc aggaacgatt ttattcttct ctgaattgca taaaatgtat
    13381 cctgaagaga agtgggatca tgtggcccat aatcatattg tctacgctag caactatcta
    13441 aaaaatgggg tccattctat ctctttattt ggtggaatta caggatttgc ttttgctgtg
    13501 ttcaatgcat ctgaaaatgg tacaagatac cagaacttat tggcaaaact ggatgaagtg
    13561 attcgtaggg tagcagagaa tgagatcgaa gaagaaaaac aaaggaatgg tctcggcgct
    13621 ctaccaactt tttatgatgt gatccaagga tattctggaa ttggaaggta tttgcttgaa
    13681 agaagaaagg atacgccagc ttttaacggc ttaattgaag cgattttgcg ccagtttgtt
    13741 gaaatgactg ccaccataac atgggaagag catgaggttc caggatggta tgttacgcaa
    13801 gagaatcaat ttttagagaa ggataaaaag atttatccat ttggcaactt caatttgggc
    13861 cttgcccatg gcatcccagg accgttaagt tttttatctt tatgcctact aaaaggaata
    13921 gagatcccag gacaaaggca agcaataacg acgattggca attggctcgt ccgtcatgct
    13981 aaaagcaatt caactggcgc cccagtttgg gctcaccgca taggcgtcaa agaagccata
    14041 gccaacaact ataccgtcac agatgaacgg gaaggctggt gttatggcaa tcctggtgtt
    14101 gcccggtcgc tctatttagc aggaaaagcg ctgaaccatc agccctatca agacatggcg
    14161 gttaaatgtt tccttggcat taaggaaaaa acattagaag aactagactt gcaaagtgcg
    14221 acgttttgcc acggaaagag tggtttgttg caaatcatgg tgcggatgaa aaacgacctt
    14281 aacatcaatg actttgacaa gctcattatt caattggaaa acgggattaa gggacagtat
    14341 aaggatcagc atccgttggg atttaaagat tttgaaatcg gaagccgaac aaacgagtta
    14401 gataaagcgg gcttattgga aggggcagct ggcgttggat tggccttatt gtcgatggtc
    14461 cgtgacgacg gtgatttctt ctgggataaa gcgtttttaa tcagttaggg gtgaggatgt
    14521 gccggaaaag gaagaaaaaa acatactagt tgggatttct ggatcgatct ctgtcataaa
    14581 catgccctcc tatttagcct tttttaaaca tacgtatggc catgtcaagg tcatcatcac
    14641 agagcaagcc aataagttgt tcccggcttc ttccttgtcg ttgttttgtg atgacatttt
    14701 ccaggatcac aatgaaacca tagatccaaa caagtcgagc catgtcgggt tagctaggtg
    14761 ggcagatcta tttattgtcc ttcctgctac ggcaaataaa atcggccaag ttgctaatgg
    14821 cttaggcatg gatctgctgt catcaaccat attagcttct acgaagcctg tacttttttg
    14881 cccaaacatg aatgaggcga tgtggaacaa tttctttgta aaaagaaaca tggcattact
    14941 tgaagaggga ggacatatga tcattcctcc agtggagaaa gaagcatatg aagtggcttc
    15001 aggaagcatt cgcaaaaact tcattattcc agatatgtat accatcgctc aagaaatgga
    15061 taaagctatg gctgtaaaag aaaaaagcta ggacgcagta cggagcgtct ggcttttttg
    15121 tgttttagcg aatttttgat ttttttctga cggggaaaag ggataatcag ttttagaata
    15181 aggagtgata gccaatggaa aaggtcattg agacaaagaa tttaacaaag aaagtaaaag
    15241 gaaaaccgtt agtggaagaa atcaatcttt ccatcgcaaa gggggagata tgtggtctta
    15301 tcggtcccaa tggcgctggg aaaacaacaa ttatgaagct gttgacagga ttgctcatcc
    15361 ctacaagcgg agaagtgaag ctcaatcaat tggatgtgca taaacaacga aaggaagcga
    15421 tgcgctccgt tggtgccatt attgaatcgc ctattttctt tgagttcatg acgggccgcg
    15481 gaatgctctt aaatcttgcc cggctccatg gcctgaacaa acaggaacgg caagagaaag
    15541 tcgcagaagc attggcgatt gttgggttag gcggccgcgg cgatgaaaaa atacgtacgt
    15601 attccttagg aatgaagcaa cgcttaggga ttgcccaagc gctgttaggc aacccagaga
    15661 ttgtcatatt ggatgagcct gccaacggct tagacccgat ggggatgagg gaattgaggg
    15721 aattgatctt gcaattaaat aaggaaagaa atattacgtt cttactatca agccacttgc
    15781 tcgacgaact ccaaaagata tgcagcacgc tcattattat caagcaggga aatgtccttt
    15841 tttatggaaa acaagaagag atttataaca aggcagagaa taatttagaa gagattttta
    15901 ttgggatgat gtcataatga gacagctaat cattagtgaa ttcgaacggt tatggtcgag
    15961 atggtccatt cggctgctcg tattgacctt gccggtgcta gtcattgcta ctggtgttta
    16021 tttccgaaac cataatcgca acatttcaat agatgctgtt gattacgcaa ccgccataaa
    16081 ttttcctatt ctcagcatat cagaacattt gtttatcacg tttaacattc tgctcatttt
    16141 tatttgtgct tatgtgctaa cagaggaata tcagcaaaaa caaatcaaat taattttgct
    16201 tcgtgcttat tccatgagcc aaatttttct gtctaaattc attgtgatgg ccacttcttt
    16261 attcatctgt ttctttcttt attatgtggc ttccttcacc gttgggcaga tgatgtttga
    16321 gacgccagaa aggtcgattc tttttggttc tgaagcagtc gttacaaatg gtgagatggt
    16381 tctttatgca ttgaactatt atggaattgc ttttcttact agtcttgcgg cactctcttt
    16441 attttgcttt attgcgattg caatgccctc tgtcaatgct ttattaggta gcggcatttg
    16501 catcctcttc tttttcattg tcggtccaca gctgttagag caatcgaccg cttttgccga
    16561 aggaagcaat gtttcttatg tggtatatgc atccataaca aaaattcaat acaccggtat
    16621 ctcgttattg ctttcaggcg gggcattgag cggttggcta atagcagtta ttttgtttta
    16681 tttgttggtc tttcttgtag gagcatattt gatttttact cgccgaaatt attatgcata
    16741 aaggagccgt atgatgaaac atttaattgc aagtgaattc gagcggcttt ggaggatgag
    16801 aatgataaaa atcctcttac tgctgctcat agggatctcc tttttttccg ctcacttttt
    16861 gacttggttt gatttaggtc tttatactgc agatagtgaa acgccgttaa atgctgttaa
    16921 ctttccctgg tttttgttaa gggaagtctc tttctttgtg acactagtca tcatgccatt
    16981 gttttgtgtg attgttttga acgcaccaat aaaagcaaaa acgtacaact tagtgttgta
    17041 ccggccattt caccgtttag aatttttact gtctaaatgg ggaacgctgc tcttgattgc
    17101 tgtcttcatt accgcgttta tctggctcat tggggtcgtg ctaggctttt tcttttacca
    17161 agttccagat tatgtgactt tttatggcga tctaacacgc tactctgtac tgaatgggta
    17221 catctattca gccaagctct attttctgtt ttgggcgatc atggtcgctg gaattgctat
    17281 tgccagtgtt atgtcgattt tggcaccaaa cccgatcatt gcttacttcc tattgatgat
    17341 tgcctacgtg gtgccgattt atttttcaaa tgagttgtcg tttttcttga tgcccactca
    17401 atccattttt atttcgcttt cggaaagcaa catgccattg ctttatatgg tgttgccttt
    17461 gattgctctg cttggcggag ggatttcaag tttattatgg gtaaagcaag attttaaata
    17521 aatgttttgt gaggggataa aatggagcac attctgattg tcgatgatga aattcaaatt
    17581 acttcaattg tgggagagct attacatgaa gaaggctacc atacaacagt cgccaacgat
    17641 ggaatgaccg cgataaagtt gatcaaggaa caggattttg atttaatcat cctcgatatc
    17701 atgatgcctt atgtgaacgg gttagacgtt tgccgtagcg taagggaatt tacggatgtt
    17761 ccgattttat ttgttaccgc tcgaacaagt atcaacgacc aaattaatgg gctaaacata
    17821 ggaggagatg actacataaa caaaccgttt acccatgaac agctgcttgc tagaatcaaa
    17881 acccatttaa ggcgggaaaa acggaaacaa caaccaacag atgaacttgt ctatggaaaa
    17941 ataacacttg accggcggac aaatgagctc cgctatggcg aaaccccatt gttgctcaca
    18001 aacaaagagt ttaaaattat ggaaatgtta atgagcaatc caaaacaagt cttttcgaaa
    18061 gaccatttat acgaaacgat ttggggagta gaagcgactg gacaatcaca cactgtgact
    18121 gaacatatcc gaaatatccg gatacgcatt cataaggtcg atccaatggc aaacctgatc
    18181 cataccgtgt ggggagtggg ctataaactt gaataaaaaa agaacgacca ttaaacagca
    18241 aatccgatta acaatagcca agacgatttt attaagtttc ttcgctacca tcattgtcgt
    18301 tttggcaagt tgggcgattg tcatgagcat cgatgaccgc tattatgcca attactatga
    18361 gagccaagtc cccaaaataa ccgatgaagt gcaaagtttg aatcgagagc tcgtcgattc
    18421 acaagtgttg ggggcacaac aactagaaaa ggccattccc accccaggaa tggaatatca
    18481 agtgctagac gaacaaggaa cattcttgta cggttcattt tccgctaacg tcaacacgga
    18541 agacgtccat ttgctaaata aggtcaacaa atcatttttg gaagataaca ccgccacaac
    18601 gtttatcccg attgtcgacc aaaatggttc atttgctggc agcgtcgtac ttcaatataa
    18661 gctagaatca gaagtcgaag ccttatttaa tatttttttt gtttgcctgt tcctcacgcc
    18721 atttttcttt attatgatct ttacctatta ttatgcgagc aaactaggaa aaaactatta
    18781 cgcaaggatc caaaagttga ttgtcgcgac agatttggtc cgaaagcaaa atttagattt
    18841 tgaaatcgag gccgacggaa atgatgaaat caccaaactt tcgacttcct tcaatataat
    18901 gaaacaagcg ttgcaagact ccctttatca gcaatggaac ttggaaaaaa accgttctga
    18961 gtttatttcc tctgtctccc atgacttaaa aacgccattg acgatcatga aagcaaacgc
    19021 gcaaatgttg gagagaaaga taaaggatga tcggaacaaa acatatattg ctaatatgat
    19081 tggcgaaatt gagcggacgg aaaacctcgt acaagagctt gatacaaaaa tgaacgacga
    19141 agagtctttt tttgccattg aaataaaaac cgtcgaacca ggtcattttt ttaaaactga
    19201 atttgcaaag tacaaagatt ttgttcaaaa cgaaggactg gagtttcaca cttccgttct
    19261 cgactacaga aaaaaagcga acacgattca gatagatgtg caaaaaataa cgcaagtgat
    19321 agacaacctc atatcaaaca gcttacgctt tgctgaacca tatgatgggc atattgattg
    19381 tcacgcagaa tgccatgacg attacgtaaa agtgactgta agcgacaatg gaaaaggctt
    19441 cactgaatca gacttgcatt acgtctttca aaaattttac cagaataacg atagtgctga
    19501 ccctcataaa ggacttgggc tttacatcgt caaacacata atcgaaaaac atggcggaaa
    19561 cgttcaagca tggaatgaca aaggcgcagt ggtttccttt cagttacctg ctgtcccgaa
    19621 aaacagccac tagcattttg cgctagtggc acttcacgct ttcgttttgt aaaataaatc
    19681 aagcttcctt catagcagtc ggacttagat cgggacaggt caaataaagt gggagaaatc
    19741 cgaaaataac atacacttgt caaataagtc gaacagaaag ttcttttgac ctcatcttaa
    19801 tgcatgaatc gactttacct cgtacaaaca tgtgattttc tatgtaataa aagaaaatag
    19861 gccttaacag gctgtttaag atctttatgt tactgttttg cctgtgtctt ttaattgggc
    19921 acatcgataa gcttagggct ggctaaaatg ccatactaga aaattgagtc atgtttaaag
    19981 ggcctccatg gccaacataa atagtatgca actcctgctt ttgtagactc tgaatgcttt
    20041 tcttttctat gtgtttgttg ttaacaaagt agtgtagatt tggtttcgtt ctatttatta
    20101 agccgcctag agatccaccc attaaaaggt cgccaataat agctaccttg ttttctaaga
    20161 acacggagat ggaaccattt gtgtgtccag gggtagaaat aatttcacct gatacaccat
    20221 aagggactaa ggaaatgttc ttgtcgatga cgatatctgc tttataccct tcttccgttt
    20281 ttgtttcaaa aaacggtaaa atcatcttgc caaatttgtt tctgccgtat aaagacgaga
    20341 tgattccttg ctccatatcg cttgcatctt ctttatgaat taatacagga gctgcaattt
    20401 tctttgtaag ttctttaact gaaccataat gatcaatatg agcatgagta ataatgatta
    20461 aagaaatatc atctttagaa attccctcat cttgtaatgc gtttaaaatt ctaggaacat
    20521 tcccttttcc accggtatcc acaatgatcg agcgcttatc tttaataata taagtgtttg
    20581 aaccttttgt tttaactgga ataacattca accagacttc cctcctttag atatttaaac
    20641 ctccatagta acaatacaca tcaaatagag tgaaaattat cctttatgaa gactcattat
    20701 aaatgaagaa tgaattacct gaaaagtttt cattcaaaaa agtaagtgat gaaccaattt
    20761 actgtattgt ttgatttatt ctctaatgat gaaagcatga ataaaaagat tagagattct
    20821 agtttgcacg atataaatat gagcttgatt ttgcattgta cattttgtat cgatcttgct
    20881 acagaaaaag tgattcccat ggaatgaaat gaacctgtgt gatactaagg ataagtgaga
    20941 taatagtagg ttctcctttt tatttaggaa gcttgggagg ttagtccaat tacgaaagtt
    21001 ccttttctgc gaaagccata gacgacttcc acccgattct ataaactgga agatgagtag
    21061 taaagccgat ttgcagatat aagaaaaaaa cgataacgaa cgattaattc gtggatatag
    21121 agagaaaagc tagtattcta ataaggcagt tgctagcaaa aatcgagaaa aacaggcatt
    21181 agccgatact taagtactaa aagaaggtgg aaacaaagtg atgaaaaaca gaataagcat
    21241 gtgcagtatt gtcctaatcg caagcatcgt ttccgggtgt agccagagtg gaagcgacga
    21301 atatattgaa gtacaaccac aaaaagaaca agctcccgct tttcagtata gattgcaaat
    21361 tgatattacg ccgcccgaag agggaagcgc ttccgaaatc atgaacaact tagctgtcta
    21421 tttacaagaa ttcgacctcg gctatgaagt gaaaggaaat cgagacgaag accggtatga
    21481 acttgattta gaactgccac gaactgcata tctaagacaa gagcccgtac aaatgagcgt
    21541 aacaggcggg ttgctagaaa gcgagtctct atatgtgaaa acggaagagt ggatcgcgtt
    21601 tgacaatgaa caaggtacct atgggtttat gctgcaaacc actccagatg tagagaatac
    21661 atatttggaa ctatccttta aagatgtcgc ctatacaccg gttgatgtgc ttgagcggga
    21721 tgagcagtat gaaacgttgg caaaagaagc agaagcaacg gttaatgaag gagagattgt
    21781 ctttaccgtt gacggcgagc aagcggcaga ctatttcagt aagctcatca agacaagcct
    21841 ttcatacagc tttccaggca tagtcgaacg atcaaatgat gaaattgaaa aaaagcttac
    21901 aataggagac gtggaggtca ccacccagat cgaggagggg gtcttgcagc gtgaaagtta
    21961 taggattccg atagaagaag acggaggtac atggacagtc gatattcaaa ttgattacac
    22021 cgacctagcg tatgtgggag aaatcggcga aattgctgac tacgaagtgc tgtcgaagga
    22081 agcttataat gattacattg taagcgaaca gcaacgagac cttgaagaat tgatcaatgc
    22141 ccttaactag cgctttggaa atgtataagc cactagcagg aatacgctag tggctcaaga
    22201 cattaaccat gctaatcaaa gcagacaatt ccttggtttt taattgcttc ggcacgggcg
    22261 tcgccaattc ctttaattcg tttcatgtca ttataagagg aaaagggccg gagttgaata
    22321 atttgtgcgg ctcgatctgg accaatttca taaatcgctt gcaactcaga ctccgaagca
    22381 ctgttgattt tcaccgttcc aggcccacaa ctatcggtac tcgcgctttc tgaagactgt
    22441 gcggtttccg tttctgtggt agcggttgca tttccactat cagtcgaggc gctggccact
    22501 tcttcttcca acttcgagat agccgtttcc ttctcttcaa tcgtttgctc tttttctttg
    22561 attttatcgt ctaatgcagc aagcttgtcc tcataatctt cgctgatttc agcagtgatg
    22621 cgttcttcca gttcttcctc gatctgttcc cgaaattcct cttcccattc gagtttggct
    22681 tcctctaatt gctcttcaat agaatcgtca gcttgtacga gctccaactg ctcttcagac
    22741 tcttttaacg attcctctgc ttcctctaac gcaacagtca attcttcaat ttctgtttct
    22801 ttgtcttgta cggatgtttc tagggtttcg attttttcta gcgaacgatc tagttgcgcg
    22861 gattgggccg tttcggacgg aagcgtgttg ccaaataaaa atgcggtaat gataaatgct
    22921 ggaatgccgt acgcaaaaac gcgctttcta gttggaaagc gaaccagagc aggcttaatt
    22981 agccctaaaa tgagaccgaa aaaagtaagc aataaaaata aaagaaataa cgtattcaag
    23041 ctagttcctc ctttgtggtg taatatggta attgtaacaa actatcagac tatcgtcatg
    23101 ggttaatttg cgtgggggaa agagttggct catttatgag tttttaataa aaataaaagg
    23161 acgcgcacct atgggttatt tgatgtacat tcatgttcta ttcagaattt agcattatgt
    23221 aaaaacaact ttgaaaccat gattatccta tttgaattgt aaatctgatt tagttttagt
    23281 cgtagacgtg tactttttta aaggacggtg tgttgatatg aaagattttc tttcgagcgc
    23341 tcttcttatt tgtggttggc tttttaccgc tatcagtgcc tatctactgt tttggacagt
    23401 ggtaactccc ttatgggcaa ttatcccttt tcttgttttc ttaagtatgg gcttgttatg
    23461 tcttcgtatt tctaaaaaac taaataatag aagacaatga acgttcttct atcaatagtg
    23521 gaaaatcaag agtagctaga aaaacactag ttgccctgtt tctcatagct accttaatca
    23581 attggtagaa actactagca atacttactg atttaaagta aactaatgga aaagacctgt
    23641 gtaataagtc gttgttttta tttagtattt tagctgattg tctggtaagg aaattatgta
    23701 aagccaaagc ttgaattcaa gaatatacta aaaagaaaca aggagaactg cgatgcaagg
    23761 aactgaccgt actgtgatga tgcattttcc taatagtcaa caagcatctt cattaaaaat
    23821 tattcaagaa ccaactagtc aaattcgtgc gttttacttt aaaaaaagtt tgttggcaca
    23881 agtggaagaa cttgagtatg caaacaatta cgctatttat tttctatttt ccgatttaga
    23941 aaatcctagt gtatacattg gtcaatcaac ccaaggcatt aaacgactga gagaccattt
    24001 acgagaaaaa gatttttggc aatacgggat cttatttgta actgataata acagctttga
    24061 taagctggcc attgactttc tagaacatca atttattcaa ctatttaaac gctcgtcctt
    24121 tattgttgaa aaccgtgacc tacgtaatac aaaaccgaca attaattggt ttgcccatgc
    24181 aaccatgaat acatttacga atcaaattac atttcttcta gaagcgcttg gcgtttctat
    24241 tcaagaagaa gagaaagaaa acgaccggaa gctttttcct gctgaaggag aacgagaggc
    24301 ttctttatac atacatgatg gacagttctt cttaacaaaa ggctcaatcc ttcatcgtcc
    24361 ccaggaacgt ctgaaaaact ggaatgatca aggaaaactt tattataagc tgaatgcacg
    24421 gattgaccag ctaatcgatg taaaacaagc agaggtgatt gacggaggaa ccgtacgtct
    24481 tcttcaggat gtcgtctgct caagtcct
//
