LOCUS       gnlProkkaIBIKFAKM_48   14407 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IBIKFAKM_48.
ACCESSION   gnlProkkaIBIKFAKM_48
VERSION     gnlProkkaIBIKFAKM_48
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 19:27:05
            Original ID  :: gnl|Prokka|IBIKFAKM_48
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 21096
            Orig. end    :: 35503
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14407
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:11612]"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11612
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     cand_cluster    1..14407
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14407
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="sactipeptide"
                     /region_number="1"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     CDS             complement(40..321)
                     /locus_tag="ctg48_24"
                     /transl_table=11
                     /translation="MSLESVKTHFTQWNGENDVTEFETSSATVEQAAETIGVSPGRIAK
                     TLSFRGEGDQAILIVAAGDAKINNKMFRQTFGLKARMLSPNGAGADRP"
     CDS             428..544
                     /locus_tag="ctg48_25"
                     /transl_table=11
                     /translation="MARCATSKCSVDEFDTSTVINTALTAKQASNNLYFHFI"
     CDS             complement(524..1669)
                     /locus_tag="ctg48_26"
                     /transl_table=11
                     /translation="MTGVISSSSIGEKINEWYMYIRRFSIPDAEYLRREIKQELDQMEE
                     DQDLHLYYSLMEFRHNLMLEYLEPLEKMRIEEQPRLSDLLLEIDKKQARLTGLLEYYFN
                     FFRGMYELDQREYVLAIQFFKKAESKLVFVKDKIDKAEFFFKMSEVYYYMKQTYVSMDY
                     ARQAFEIYSEQTTYDIRMIQCQSLFGANFLDLKQYEKAIAHFQKAFTLAKTEQQPQLMG
                     RTLYNIALCKQNQNSFESAIEYVKKSIQVFEGSKMLPSLPQAFFLITQIYFKLGKIDNA
                     CEYHKKGKEYSAAAGDTVYLTEFEFLESLYLSGPDEERIEKCFVFLESKMMYADIEDFA
                     LDVAKYYHQQENYKKASHYFLKVEEARQHIQGGVNLYEMEV"
     CDS             1899..3254
                     /locus_tag="ctg48_27"
                     /transl_table=11
                     /translation="MRKNKLSFKEKAGAEQEECLCFCEGEASREAMFQAPIELPEGFVV
                     DPAEAVANVTWNADSLSCVSDRCLIQTGPEPDEVGVQFAVRLQGTVTLLVSVSPVRNQY
                     GQGDGAVSVIHNAEIDQVVYYSDEPDDCPDISNITIENLVVVPPFYGSPLSVTGTIVLV
                     PEPEPVYAFTANPNDQSVSVIDTNTHTVVTTIALPYNAAGIEITPDKSAVFVLHPNNNV
                     ISVIDYDTLTVTATILLDQPPRLIRFIPNHEFAYVFTGTAIYVIGIDTLTVERSIPVEG
                     FDIAIDPNGLFAYVLNFGLVQKVDLSTGEVTGTIERELIVSSIETDSPERYAYVLEQEF
                     LFNYLTVIDLNTFTISNTQELEPDGQYRMFTSGTGVYLYDDFTGNLYSVSPNGAGVIGN
                     LPQSARDFAFTPNGDFLYATRFIEQSIIVYNTDDYSEETVISLGVSPGAITI"
     CDS             3293..4669
                     /locus_tag="ctg48_28"
                     /transl_table=11
                     /translation="MKKNDLSALQENCFCFCDEEISREAPFQVPIDIPKGFKVDSAEAS
                     AAVTWSTDNLSCVSEPCLIQTGPETEDIGVRYAVRVQGTIMLLVSVSPVRNQYGQGDGA
                     VSVIHTEEIDQVVYYAAQSDRCPDFSQMTVEDLLIVPPFYGSPLTVAGTLVLPPSPDPQ
                     SYVFTANTGDSTVSVIDADLNTVVKTILFSAVPTNLGVTFDKAFTYVLHGNTNLVSVID
                     NKTLTIINTITVGGGPRKIEFDPTDEYAYVMAAGSIYMIDTANQSVIDVIAIPGALDFA
                     LDPNGQYVYTANGSSWSVDKYDVNTGQLVESIIDTFEFPSLIATPYAGNFAYVLNGELW
                     PKGVTEISLSPLSRGGDFSRLFETLRTIVFSLDSTRAYFLEPYSEPFLINNLYVVNTAR
                     QRIIANVSLPGAFDLAVTPDKQYIYAAQPNDNAVTVYRTSDYTAVTVIPVGAGPSAIAM
                     "
     CDS             complement(4675..5376)
                     /locus_tag="ctg48_29"
                     /transl_table=11
                     /translation="MKKSTVFTLLLLLIGMAAYSFGWVQAVAEAAAQYVQMINNDAVRL
                     GLLACTAALLMLPAFLYLHYVTQSVKNMTAAFQKLTQSHQSCCDFQQHNLCSRYAEDVK
                     SLRDSYKNVRQTYVMAAVLCQVIIFGCMFEIVKAVPFRLHTPPALSMGLAMLLILYLLF
                     CMRTYLRQLFRHGSLFRKVFAGALAAAGIWWMLSFSISELLFLIILATIQQIGSFIYKR
                     FSYRSTASLDL"
     CDS             complement(5373..6653)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_30"
                     /sec_met_domain="Peptidase_M16 (E-value: 8.8e-15, bitscore:
                     46.4, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKAFFQQLDERTDIRYTDSGLKIFRLKFPRAHLRLCNVKIDFG
                     SRDVCIRAESGDTLLPYGTAHFLEHLLFWHNGRNLYSDFFAHGALLNAFTTYTDTNFMF
                     TSLPDRLRQTIPILLDALWNHSFDKKIVAQEKAVITSEIQTAHLNDQLSYHYQLISMLS
                     PSSPAAVFPAGRIEDIEALDISDLQKAYKAAYQTHRMTLFLIGGSENTETLLPPHLQLE
                     KRPDYHAERKIIPACPPALSQKMMLGDEERMEDTWTGLQIGALPGQNDLWVIKLYWDIA
                     ARILFQLDSPFFQEIQQTYRLEIDRLSAETYIYEDGGFLILHSQGTHSSAYIDVASYYV
                     TQKKEQVAAWLQYGKDSLTDAIIYDSDYVRKCFEWAAECDRCDCSFLDMYHIIQDMDAQ
                     VFLSLIDAMASSNKAIIHVSQKEAIRQ"
     CDS             complement(6658..7842)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_31"
                     /sec_met_domain="Peptidase_M16_C (E-value: 5.5e-07,
                     bitscore: 21.2, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQAKENGLEVNLLKTHQFSTISIAASFLKPIESAAEPEEETIYF
                     YGAAAYLKEQIIDDFGCAAGSRFMYSANLFFDQQLKTCGTRLIHPLYNGNLHVDALMKT
                     FADLSFPSSLSFEAVEKARNELLLKIEKKFTDPFSYSAARLAEEVFGNPMYGTGMFGRK
                     DRIKAIHPKRFHDATDFIVDLASQQKQLNILGQVQACDVRGHAPQTSAVTSERIPVNRH
                     VFETETRSAAGPSVLTLGFDCGEMKDASDYIKIQLIDGLLGKYGHSALFKHFREKDLAV
                     YHVITRYDVMNNLLLVSICTDQLHEIDIPPRVLEAVSAFHTDERELEQAKQFLRNELLL
                     QFDSPEGLLAYMGILRRFSCTKEALLDGISAVTCRDVLQFIATINYIGAHVVRG"
     CDS             complement(7808..8572)
                     /locus_tag="ctg48_32"
                     /transl_table=11
                     /translation="MPAATLPLCAVHMLWAVVIDFPVFLQAPPQQSRMHSFMRRSEFSF
                     YKREWNRFISSKAMLLNYAVMAAFSGFFSFQMMNTGIFNQQVIYIVISALLLICSPIAL
                     LYSIEKNDRMLLITLPIKRKTMFWAKYRFYSGLLAGGFLLVVMIVGFISGRPISVLTFL
                     QCIELLLAGAFIRLTADKKRPFFSWQTEQQLWSGFSKYRSYLFCLPLFLATLTGTAVSL
                     AVIPIAGLVIVYYLQKQDGGFFDTSKRERLGS"
     CDS             complement(8514..8891)
                     /locus_tag="ctg48_33"
                     /transl_table=11
                     /translation="MEGILYETELPAADFFTELLARPECRFVCRYLFEKNVILFYFTAV
                     LIWKRNAVRGANIVLARQVFVFYRLLHYFRSCAKQPLRQKEELDVSAACGDIRLCMSQR
                     RFDAGRHASALRGAYAVGGGH"
     CDS             complement(9111..9830)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 124.3; E-value:
                     1.1e-37)"
                     /gene_kind="transport"
                     /locus_tag="ctg48_34"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYERDNVILEQVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGRFTLCGIEAEAGMPQKTSDQLKTHRYFAADYPLLFTEITAKDYVS
                     FVHSLYQKDFSEQQFASLAEAFHFSKYINRRISELSLGNRQKVVLMTGLLLRAPLFILD
                     EPLVGLDVESIEVFYQKTREYCEAGGTILFSSHLLDVVQRFCDYAAILHNKQIQKVIPI
                     GEETDLRREFFEVIGHE"
     CDS             complement(9827..9988)
                     /locus_tag="ctg48_35"
                     /transl_table=11
                     /translation="MSPAQRRILLYILSFIFVIGAVVYFVKSDYLFTLIFIAIAILFGM
                     RARKADSR"
     CDS             complement(10001..11347)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_36"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1081.4, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 5e-31,
                     bitscore: 98.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.3e-09, bitscore: 28.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.1e-23, bitscore: 75.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 5.1e-12, bitscore:
                     37.5, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.6e-11, bitscore: 36.0,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIEQMFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLN
                     KTAYELCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQLGNRAIR
                     HTITTSGSNEFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSIEQFKKTADMLFDN
                     GVLTCEITGGEIFVHPNANEILDYVCKKFKKVAVLTNGTLMRKESLELLKTYKQKIIVG
                     ISLDSVNSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKV
                     RDLGAKAFSYNWVDDFGRGRDIIHPTKDAEQHRKFMEYEQNVIDEFKDLIPIIPYERKR
                     AANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFNSPLVHKLWQAQAPRF
                     SEHCMKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     CDS             complement(11481..11612)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_functions="biosynthetic-additional (sactipeptides)
                     predicted sactipeptide"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_37"
                     /sec_met_domain="Subtilosin_A (E-value: 8.9e-31, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       complement(11583..11612)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="ctg48_37_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       complement(11481..11582)
                     /prepeptide="core"
                     /locus_tag="ctg48_37_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="33.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[11582:11612](-)"
     CDS             11927..12355
                     /locus_tag="ctg48_38"
                     /transl_table=11
                     /translation="MKQETPITLHVKSVIEDDGNQEVIEFRTTGFYYVKQNKVYLSYYE
                     EHDLGKVKTIVKVSEGEVLVMRSGAVKMNQRFVKGASTIAKYKMSFGELELKTSTKSIQ
                     SDLDEEKGRISIAYDMHVGDEQEHLHNMTITYEGGTHA"
     CDS             12352..14022
                     /locus_tag="ctg48_39"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLEIPKDKTHGD
                     YSTNMAMQLARVAKKAPRQIAEEIVAHFDKGKASIEKLDIAGPGFINFYMNNQYLTKLI
                     PSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRF
                     VNEEESERLAFFREYGLKYELEKLRKDLENFRVPFDVWYSETSLYQNGKIDKALEALRE
                     KGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWG
                     ADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKP
                     AADLDFSHIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     CDS             complement(13986..14159)
                     /locus_tag="ctg48_40"
                     /transl_table=11
                     /translation="MGALFLHLKPDEYLKKLYKTKKLVEKTSFSLQAKDKVRRLCPFDR
                     DYIFSGADTPIS"
     CDS             complement(14164..14406)
                     /locus_tag="ctg48_41"
                     /transl_table=11
                     /translation="MRHVLEDLTEKVRQNRLSVSGKNLYKKRKEKIERSFADSKQLHGL
                     RYCRLRGKRNVSEQVLLTAACQNMKKIATYLAKQG"
ORIGIN
        1 ggatcatgag ccaatccaat tgggcaaact cctccaattt catggcctgt ctgctccagc
       61 accattggga gagagcattc ttgcttttaa gccaaatgtt tgcctgaaca ttttgttgtt
      121 gattttggca tcgccggctg ccacaatcag aatcgcctga tctccttccc ctctgaagga
      181 cagggtcttg gcgattctac ccgggcttac gccgatcgtc tcagctgcct gttcaactgt
      241 cgcgctcgac gtttcgaact ccgtcacatc attttctcca ttccactgtg taaagtgggt
      301 ttttacactt tccagagaca tgctgcattt ccactatctt aaagattatt gaaaagatca
      361 tagcatggat tgggagactt tggtaaataa gggacgaaaa aaccgccgat ggacggcggt
      421 ttagatcatg gcgcgttgtg caacatcaaa atgttctgtt gatgaatttg atacctcgac
      481 tgtgataaat acagcactca cagctaaaca agcgagtaat aatttatact tccatttcat
      541 ataaattcac ccccccttga atgtgctgtc ttgcttcttc aacctttaaa aagtaatgag
      601 atgctttttt gtaattttcc tgttgatgat aatatttagc aacatcaagt gcgaagtcct
      661 caatatctgc atacatcatt ttactttcaa gaaaaacaaa acatttttct atccgttcct
      721 catccggtcc agacaagtat aaagattcca aaaattcaaa ctccgttaga tacacggtat
      781 ctcccgcagc tgcagaatac tcttttcctt ttttatgata ttcacaggcg ttatcaatct
      841 tacctaattt aaaataaatt tgtgtaatta ggaaaaaagc ttgtggcaat gaaggaagca
      901 ttttagatcc ttcaaatact tgaatagatt tttttacata ctctatcgct gattcaaaac
      961 tgttttggtt ttgcttgcag agtgctatgt tataaagtgt tcttcccatt aattggggct
     1021 gctgctctgt ttttgcaagt gtaaaggctt tttgaaaatg ggcaattgct ttttcgtatt
     1081 gttttaaatc caaaaagttg gctccgaata aggactggca ttgaatcatt ctgatatcat
     1141 atgtagtctg ttcactgtat atttcgaatg cttgacgtgc atagtccatg gagacataag
     1201 tttgtttcat ataataatag acttctgaca ttttgaaaaa gaattcagct ttatcgattt
     1261 tatctttcac aaaaaccagc ttgctctcag cttttttaaa gaattgaatg gctaatacat
     1321 attcccgctg atccagctca tacatgcctc tgaagaaatt aaaatagtac tcaagcagac
     1381 ctgttaaacg agcctgtttt ttatcaatct caagcaggag atcagacagt ctcggctgtt
     1441 cctcaatcct cattttttct aacggttcaa ggtactcaag catcaggttg tgccgaaact
     1501 ccatcagtga atagtacaaa tgaaggtctt ggtcttcttc catttgatcc agctcttgct
     1561 tgatttctcg tcgcaaatat tctgcatcgg gtatgctgaa tcggcgtatg tacatatacc
     1621 attcgttaat cttttctccg atggaagaag aagatatgac acctgtcacg tttgcaaatc
     1681 cctcccttca taattctata tatgtcatat tttatcatca acattcttgt gagaagcgca
     1741 aaaaaaccgc aattttttct ttcgttacac cgcatgtttg gagatatatt ttcaaaaaga
     1801 agcgtttacc ctcagtaatt tgtacaagca aacacgttac tcttccatat tctgttatat
     1861 ctgcgtgagc agtgtatgtc tgaaaaggaa gtgaaggaat gagaaaaaat aagctttcct
     1921 ttaaagaaaa agcaggagca gaacaagaag agtgcttatg tttttgtgag ggagaagcaa
     1981 gccgagaagc catgtttcaa gcgccgattg aattacctga aggatttgtc gttgatccgg
     2041 ctgaagctgt tgcaaacgtg acgtggaatg cagacagcct ttcttgtgtc agtgaccgtt
     2101 gcttaattca aacggggcca gagcctgatg aggtcggtgt tcaatttgca gtgcgtctgc
     2161 agggaaccgt tacgctgctc gtcagtgtct cacctgtgcg aaatcaatat ggacaagggg
     2221 atggggctgt ttccgtcatt cacaatgcag aaatcgatca agtcgtctat tattccgatg
     2281 aaccggatga ttgcccggat atcagtaaca tcacgattga gaaccttgtt gttgttccgc
     2341 cgttttacgg cagtccttta tcggtgacgg ggacgattgt gcttgtaccg gagccggaac
     2401 ccgtctacgc gtttacagcg aatccaaatg atcaatcagt ttctgtgatt gatacaaaca
     2461 cccatactgt tgtgacaacg attgctcttc cgtacaatgc ggcaggtatt gaaattacgc
     2521 cagataaaag cgctgtgttt gtcttacatc ccaacaataa tgtgatttct gtcatcgatt
     2581 atgacacatt aacagtgaca gcaactatat tgctggatca gccgcctcga ttgattagat
     2641 ttatccctaa tcatgagttt gcttatgttt tcaccggtac tgccatttat gtgattggaa
     2701 ttgatacgtt gactgttgag aggtctattc ctgtagaagg ttttgatatt gcaattgacc
     2761 ccaatgggtt gttcgcctat gttcttaatt ttggtttagt tcaaaaagtg gacctatcca
     2821 ccggtgaagt cacaggaacg attgaacgag agcttatcgt atcatccata gaaacagatt
     2881 ctccggagcg gtatgcgtat gtcttagaac aagaattctt attcaattat ttgacggtta
     2941 ttgacttaaa tacgtttacg atcagcaata cccaagaact ggagcctgac ggtcaatata
     3001 gaatgtttac gagcggaaca ggtgtgtatt tatatgacga ctttaccggc aatttatatt
     3061 ctgtcagtcc gaatggtgca ggcgttatag gaaatcttcc gcaatcggca agagactttg
     3121 cgtttactcc gaatggcgat tttctgtatg caactcgttt tatagagcag agcatcattg
     3181 tttacaacac agatgattat tctgaggaaa ctgtgatatc tcttggggtt tcaccgggtg
     3241 ccattacgat ttaaccgctg catgttgtgc atttttaaaa ggacgtgaat tcatgaaaaa
     3301 gaatgatctt tctgctttac aggaaaattg tttctgtttt tgtgatgagg aaattagccg
     3361 ggaagcgccg tttcaagtgc caatagatat ccctaagggc ttcaaggttg attcagccga
     3421 agcgtcagcg gctgttacat ggagtacaga caatttgtcc tgtgtcagtg agccttgctt
     3481 aatccagact gggccggaaa cagaagatat tggtgttcga tatgctgtga gagtacaagg
     3541 gaccattatg cttcttgtca gtgtgtcgcc tgtgcgaaat caatatggac aaggagacgg
     3601 ggcggtttct gtgattcata ctgaagagat tgatcaagtt gtttattatg cagcacagtc
     3661 tgaccgctgt cctgatttta gtcagatgac agtggaagat cttctcatcg tgccgccttt
     3721 ctacggcagt ccgctcacgg tggccgggac acttgttttg ccgccatcgc cagaccctca
     3781 atcgtatgtg tttactgcca atactggaga cagcacggtt tcggtcattg atgcagattt
     3841 aaacactgtt gtaaaaacaa tcctgttttc tgctgtgcca actaatctag gcgttacttt
     3901 cgataaagca ttcacgtatg tcctccatgg gaataccaac cttgtctcag tgattgataa
     3961 taaaacatta accatcataa ataccattac tgttggagga ggaccgagaa agatcgaatt
     4021 tgatccaaca gatgagtacg cctacgtgat ggccgccgga tctatatata tgattgacac
     4081 ggccaatcaa tcagtaattg atgtaatcgc gatacccggc gctttagact ttgctcttga
     4141 tccgaatgga cagtatgtct ataccgctaa tggaagcagt tggtcggttg ataaatatga
     4201 tgtaaatact gggcagttgg tagaaagtat catagataca tttgaatttc ccagtttaat
     4261 tgcaactcct tacgctggaa attttgcgta cgtgttgaat ggtgagctgt ggccgaaagg
     4321 tgtaacggag attagtttgt ctccattaag caggggaggg gacttcagcc gtttatttga
     4381 aacgctgagg acgattgtat tttctctcga tagcactaga gcttattttc tagagccata
     4441 tagtgaaccg tttcttatta ataacttata tgtagttaat acggccagac agaggatcat
     4501 tgcaaacgtg tctctccccg gcgcttttga cctcgccgta acgccggaca aacagtatat
     4561 ttatgcggca cagcccaacg acaatgctgt gaccgtgtac cgcacaagtg attatacagc
     4621 cgtgacggtg attccggttg gcgcgggtcc gtctgcgatt gcgatgtagc tattttatag
     4681 atcaagagaa gcggtgctgc gataagagaa tcgtttataa ataaatgatc cgatttgctg
     4741 aatggtagcc aggataatca gaaacagcag ttcacttata gagaaactga gcatccacca
     4801 aatcccggct gctgccagcg ctcccgcaaa cacttttctg aacaggctgc cgtgccggaa
     4861 aagctgccgc aaataagttc gcatgcaaaa caataaatac agaatcagta gcatcgcaag
     4921 tcccattgaa agggcagggg gcgtgtgaag gcggaaaggg acggctttaa cgatttcgaa
     4981 catgcagccg aatatgatga cttggcacaa cacggcagcc atcacgtatg tttggcggac
     5041 gtttttatag ctgtcacgca gcgatttgac gtcttctgca tatcggctgc acaagttgtg
     5101 ttgctgaaag tcacagcagc tttgatgaga ctgtgtgagt ttctgaaaag ctgctgtcat
     5161 gtttttcacg gattgggtga cataatgaag atatagaaaa gcaggcagca tcaggagggc
     5221 agcggtacaa gccagcagtc cgagccgaac agcatcattg ttgatcatct gtacatattg
     5281 ggcggcggct tcggcaacgg cctgaaccca tccgaaggaa taagccgcca tacctataag
     5341 cagcaataaa agggtaaaga cagtgctttt tttcattgtc tgatcgcctc tttctgagaa
     5401 acgtgaatga tcgctttgtt agaagatgcc attgcatcaa tgagagacaa gaaaacctgc
     5461 gcatccatat cttgaatgat gtggtacatg tcaagaaacg agcaatcgca cctgtcacac
     5521 tcggctgccc actcgaagca tttacgcaca taatcgctgt cataaatgat cgcgtctgtc
     5581 aaagagtcct tgccgtattg aagccaggcg gcaacctgtt ctttcttctg tgtgacatag
     5641 tatgaagcca catcgatata agctgaagaa tgggtccctt gactgtgaag gatcaagaaa
     5701 ccgccatcct catagatata agtctcggct gacaagcgat cgatttccag acggtacgtt
     5761 tgctgaatct cttgaaaaaa cggtgaatct aattgaaata gaatacgagc cgcgatatcc
     5821 caataaagct ttatcaccca cagatcgttt tgcccgggaa gtgcgccgat ctgtaatccg
     5881 gtccatgtat cttccatccg ctcctcatca cccagcatca ttttttgtga gagggctgga
     5941 gggcatgccg ggatgatttt tctttcagca tgataatccg gacgcttttc cagctggagg
     6001 tgaggaggca aaagcgtttc tgtattttct gagcccccaa tcaaaaacag cgtcatccga
     6061 tgggtttggt aggcagcctt ataggctttt tgtaaatcac tgatgtccag cgcctcaata
     6121 tcttcgattc tgcctgcggg gaaaacggca gctggtgagg agggagaaag catgctgatc
     6181 agctgataat gatatgagag ctgatcgtta aggtgtgctg tttgaatttc gcttgtaatc
     6241 acagcttttt cctgagcgac aatcttcttg tcaaatgagt ggttccataa agcatcaagc
     6301 aggatgggga tcgtttgtct gagccgatcc ggtaatgagg taaacatgaa attggtatcg
     6361 gtgtaggtag tgaatgcgtt taaaagcgcg ccatgcgcaa aaaaatcact gtacagattg
     6421 cggccgttat gccagaagag aagatgctct aaaaaatgcg ctgtgccata cggaagcagt
     6481 gtatcaccgg attctgcccg tatacataca tcccggcttc caaaatcgat ttttacattg
     6541 cacagccgca ggtgggcgcg ggggaatttc aatctgaata tttttagtcc gctgtctgtg
     6601 tatctgatat cggttcgttc atccagttgt tgaaaaaagg ctttattttc catctcttca
     6661 tccccttact acatgagctc cgatataatt gatggtcgct atgaattgca atacatcacg
     6721 gcatgtaacc gctgagatgc catccagcaa ggcttctttc gtgcaggaga agcggcgcag
     6781 gatccccata taggccaata gaccttcggg agaatcgaat tgcagcagca attcattgcg
     6841 taaaaactgc tttgcctgtt ctagttcccg ctcatctgta tgaaaagctg agacagcttc
     6901 caaaacgcgc gggggaatgt ctatctcatg aagctgatct gtacatattg aaacaagcag
     6961 caaattgttc atgacatcgt aacgggtgat aacgtgatag actgccagat ctttctctct
     7021 gaagtgcttg aataaagcgg aatggccgta ctttcccagt aatccgtcta ttagctgtat
     7081 tttgatataa tcactggcat ctttcatctc tccgcagtca aatccgagtg tcaagacgga
     7141 aggacctgca gcgctgcgtg tctctgtttc aaaaacatgc cggtttacgg gtattctttc
     7201 ggacgttaca gcggacgttt gcggggcatg tccccgaaca tcacatgctt gtacttgtcc
     7261 caatatgttc agctgttttt gctgggacgc taaatcaacg ataaagtccg ttgcgtcgtg
     7321 aaaccgttta ggatgaatcg cctttatcct gtctttccgg ccaaacatgc ctgtgccgta
     7381 catcgggttt ccgaagacct cctcagccaa gcgcgccgcc gagtaggaga agggatcagt
     7441 gaatttcttt tcgattttca gcagcagctc attcctggcc ttttcaactg cttcgaatga
     7501 aagagaagaa gggaaagaca agtctgcaaa agttttcatc agggcgtcaa catgaagatt
     7561 cccgttatat aatgggtgaa tcaaacgggt cccgcaggtt ttcagctgct gatcaaaaaa
     7621 gagattcgct gagtacatga aacggctgcc ggcagcacaa ccgaaatcgt caatgatttg
     7681 ctccttcagg tatgcggcgg cgccgtaaaa ataaatcgtt tcttcctcag gttccgccgc
     7741 gctttcgatc ggtttcagaa agctcgcggc gattgatata gttgaaaatt gatgagtctt
     7801 cagcaggtta acttccaagc cgttctcttt tgcttgtatc aaagaaacca ccatcctgtt
     7861 tttgcaggta atagactatg accagaccgg ctatcggaat gaccgccaag gatacagcgg
     7921 tgccggttaa tgtggctaag aataggggaa gacaaaacag ataagaccga tattttgaga
     7981 aaccgctcca tagctgctgc tccgtctgcc agctgaagaa gggccttttt ttatccgcag
     8041 ttaacctgat aaaagctccc gccagcagca actcaatgca ctgcaaaaaa gtgagaactg
     8101 aaatcggacg gccgctgatg aaacccacaa tcatcacgac aaggagaaat ccgcctgcca
     8161 ataggcctga ataaaagcga tatttcgccc aaaacatcgt tttccgcttg atcggaagcg
     8221 tgatgagcag catgcggtca tttttttcaa tcgagtacaa aagggcgatc ggcgagcaga
     8281 tgagcagaag cgcggaaatc acgatataaa tcacttgctg attgaagatg ccggtattca
     8341 tcatctggaa cgaaaagaag ccgctgaacg ccgccattac cgcgtaattt aacagcatcg
     8401 ctttagaaga gataaatcgg ttccattctc ttttgtaaaa cgaaaactca gatcgccgca
     8461 taaatgaatg catcctgctc tgctgcggag gcgcctgcag aaagacagga aagtcaatga
     8521 ccaccgccca cagcatatgc accgcgcaaa gcggaagcgt ggcggccggc atcaaagcgg
     8581 cgctgagaca tacacaggcg aatatcgccg catgcagcag aaacatcaag ttcttctttt
     8641 tgacgaagtg gttgcttagc acaactccga aaataatgga gtaaacggta aaaaacgaaa
     8701 acctgccgag ccaaaacaat gtttgcgccc ctgacagcgt tccgtttcca aataagaaca
     8761 gcggtaaaat aaaaaagaat aacgttcttc tcaaacaggt atcgacaaac aaaacgacac
     8821 tctgggcgag ccaaaagctc cgtgaagaaa tcggcagcag gcagctcagt ttcatataag
     8881 attccttcca ttgagatgtc acagaaagaa acaccatata tgcgttcatt aagagaagcg
     8941 cgagtatgat atacgttttg cgcaacaccg attcatcaat gccggcctgg cggatcagcc
     9001 cgatttcaaa tacggccaga atgacaaggc ctgcggcaat gcggatggcg tcctttttcc
     9061 cttgccggct gtaaagctgt ttgaacagca aagacatgat ggggattatg ttattcatgg
     9121 ccgatcacct cgaaaaattc ccgccgcaga tcggtctcct ctccaatcgg aatgaccttt
     9181 tggatctgtt tgttgtgaag aatggccgcg taatcacaaa atctttgcac gacatcgagc
     9241 agatgagaag aaaacaaaat ggtcccgcct gcttcacagt actcgcgcgt tttctgataa
     9301 aaaacctcta tcgattccac atccaaaccg acgagcggct catccaaaat aaatagggga
     9361 gcgcgcagca ataagcctgt catcaataca accttttgcc tgttccccaa ggacagctcc
     9421 gaaattctcc tgttgatgta tttcgaaaaa tgaaaggcct cggccaaact ggcaaactgc
     9481 tgctctgaaa aatccttttg ataaagcgaa tggacgaaag acacatagtc cttcgccgta
     9541 atttctgtaa atagcagcgg ataatcggcg gcgaagtaac ggtgagtctt cagctgatct
     9601 gatgttttct gcggcatgcc ggcctccgct tcaattccgc acagtgtaaa gcgcccgctg
     9661 aaattgcggt tcacgcctgt cagcgtatta atcagtgtcg tttttccggc gccgtttacc
     9721 ccaagcagcc cgtaaacggc gcctttttct aaatgtaaat ccacttgttc taagatgacg
     9781 ttgtcccgtt cataccaaac ggatacatcg tgtatatcca aaatgctcat cgcgagtcag
     9841 ccttccgcgc gcgcattccg aacagaatgg caatggcaat gaaaatcagc gtaaacagat
     9901 aatcgctttt gacaaaatag acgactgcgc cgatgacaaa gataaatgaa aggatataca
     9961 gtaaaattct tctttgtgct ggtgacaaat cgtttccctc ctaaataagc tggaccacgt
    10021 cttctaattg ttcatttttc gcccaagagc aaatgttttt tcggtgatat ttgttagagt
    10081 tcagcccttt taagtaacag cctccgcaat agccgctgaa cgggcatttg tctttcatgc
    10141 aatgttcgct gaaccgcggc gcctgcgctt gccacagttt atggacgaga ggggagttaa
    10201 agatgctttc ataggaatca tgaaaaatat ttcccaatga aaattccttt ggaaagaggg
    10261 cgcaaggacg tacttcgccg aacgggctga tcacaatgga cttccagcca gcgccgcaat
    10321 ttgccgcgcg ttttctctca tagggaataa tcggaatcag atctttaaac tcatcaatca
    10381 cattttgctc gtattccata aacttgcggt gctgctcggc gtctttcgtt ggatggataa
    10441 tatccctgcc tcttccgaaa tcgtcaaccc aattgtaaga aaacgccttc gctccgagat
    10501 cccgaacctt ttgggccata tcgtggattt cccacatgtt tttttcgaag acagacatgg
    10561 cgactctgac aaatataccg tggtcactca acaattttat cgttttacaa gtttgggcaa
    10621 aagagccttt tctccctcta aaggagtcat ggacctcgga attgacacta tcaagagaaa
    10681 tgccgacgat gattttttgc ttgtaagtct tcaaaagctc caggctctct tttcgcatga
    10741 gtgttccgtt tgttaagaca gcgacttttt tgaacttttt acacacatag tcaagaatct
    10801 cattggcgtt tggatggaca aaaatttctc cgcctgtgat ttcgcatgtc aatacaccgt
    10861 tatcaaacag catatcagcc gtttttttga attgctcaat cgacacggtg ccgagcgctt
    10921 caggcgagct ttccaaataa cagtgggcgc atttcaaatt acagcggtgc gtcagttcaa
    10981 aggtggcgtg caggggcatc ggaaattcat tgcttccgct cgtggtgatg gtatggcgga
    11041 tggcccggtt tccaagctgg ataacctgct tgttctggag catgttgagc atgtcgtaat
    11101 accaatcttt atggtcttcc ggtgattcat catacactgc acattgctca gctaaaatct
    11161 gctcagctgt tttttggcca tccatgcgca tgcagagctc gtaagctgtt ttgttgagat
    11221 ccaaatactc aaagtcagaa atggagacat tatcgcgcaa gtagtcgatt tctaacacgc
    11281 cgccctcagg aagctggtga actcttacac tttcattaat aaatggaaac atctgctcta
    11341 taaacaaaat accatcccct atacatatga ttcaaatgaa aaacggttgt gtatgtatat
    11401 ccaagaggta gattttagtt aaaaattgta atttacttaa aaagggcata gtagaatgac
    11461 tatgcccttt tgggagatcc ttacccccat agaccgaata gacctgttgc accggcaatt
    11521 tcaaaatcag ggataggacc gtccactaga caagcggctc cgatcgagca tgttgcacaa
    11581 cctttgtttt ctacaatgac agcttttttc ataattgaat cctccctttt tttttgtttt
    11641 tctaacagat ctatgttgta cttttatctt aaaactatca aattactaat tcaatacata
    11701 tattttgaaa aaaatgtgaa aaggaaatga tagatttcgg aaaaatgtaa catttactaa
    11761 aggtaattag tgatatgatt ttctcttcta tataaggaaa tgctttttat gaggtttatc
    11821 ttcaaatctg atgagcaatg atggtaagat agaagcagtt gaagtttaca aaccgaatga
    11881 ttatactatt caagtcaaag tggaatgatg aaaaggacgt gtcagaatga agcaagagac
    11941 accgataaca ctccatgtga agtctgtgat cgaggatgac ggaaaccaag aagtcatcga
    12001 attccgcacc accggatttt actatgtaaa acaaaataaa gtgtatctat cttattatga
    12061 agaacacgac ttaggcaaag tcaaaacgat tgtgaaagta agcgaaggcg aagtcctggt
    12121 catgaggtca ggcgctgtca aaatgaatca gcgtttcgta aagggagctt ccacaattgc
    12181 taaatataaa atgtcatttg gtgagcttga gctgaaaaca agcacaaaat cgattcaatc
    12241 tgatctcgat gaagaaaaag gccgtatcag catcgcatat gacatgcatg tcggagacga
    12301 gcaggagcat ttacataata tgacgatcac gtatgaggga ggaactcacg catgaacatt
    12361 gcggaacaaa tgaaggacgt gctgaaagaa gaaatcaaag cggccgttct gaaagcggga
    12421 ctggctgaag aaagccagat tcccaatgtt gttttagaaa taccgaaaga taaaacacac
    12481 ggcgactact caacgaatat ggcgatgcag ctggcaagag tggcaaaaaa agcgccgcgc
    12541 caaatcgctg aagagattgt cgcccatttt gataaaggaa aggcttcgat tgaaaaactg
    12601 gatatcgccg gcccgggttt tatcaatttc tatatgaaca atcaatattt aacaaagctg
    12661 attccgtctg tactggaagc aggggaagca tacggggaaa cgaacatcgg aaacggtgaa
    12721 cgagttcagg tagaattcgt atcagcgaat ccgacgggag accttcacct cgggcatgcg
    12781 cgcggggcgg ctgtcggcga ttccttgtgc aacgtgcttt caaaagcggg ttacgatgta
    12841 agccgcgaat actacattaa cgatgcgggt aaccaaatca acaatctggc gctttctgtt
    12901 gaagtccgtt actttgaagc actcggattg gaaaaaccga tgccggagga tggctaccgc
    12961 ggcgaggata tcattgcgat cggaaagcgt ctcgctgagg aatacggtga tcgtttcgtt
    13021 aacgaagaag aaagtgaacg cctcgcgttt ttccgtgaat acggcctgaa atatgagctg
    13081 gaaaagcttc gcaaggactt ggaaaacttc cgtgtgccgt ttgatgtgtg gtattcagaa
    13141 acttcactgt accaaaatgg aaaaatcgac aaggcgcttg aagcgctccg cgaaaaaggc
    13201 catgtctatg aagaagacgg cgcgacttgg ttccgttcca cgacgtttgg cgatgataaa
    13261 gaccgcgtat tgatcaagaa ggacggcacg tacacgtacc tgcttcctga tatcgcgtat
    13321 cataaggaca agcttgaccg cggctttgat aagctgatca acgtttgggg cgccgatcac
    13381 cacggctaca tcccgcgtat gaaagcggca atcgaagcgc tgggctatga aaaaggaacg
    13441 cttgaagtag aaatcattca gctcgttcac ctttacaaaa acggcgagaa aatgaaaatg
    13501 agcaaacgga ccggtaaagc cgtaacgatg cgtgacctga ttgaagaagt cggcttggat
    13561 gccgttcgtt acttctttgc gatgcgaagt gcggacaccc atatggattt tgacttagat
    13621 cttgctgtat caacatctaa cgaaaaccct gtgtattatg cacaatacgc gcatgcacgt
    13681 atttgcagca tgcttcgcca aggggaagag caggggctta aaccggcggc agatcttgat
    13741 ttcagccata ttcaatcaga aaaagaatac gatctgctga aaacgatcgg cggcttccca
    13801 gaggcagtgg cggaagcagc ggaaaaacga attccgcacc gtgtcactaa ctatatttat
    13861 gatctggctt ctgctctgca cagcttctac aacgcagaga aagtcatcga ccctgaaaat
    13921 gaagagaaaa gccgcgcgcg cctggcttta atgaaggcaa cgcaaattac gctgaacaat
    13981 gcgcttcagc tgatcggcgt atcggctccg gaaaaaatgt aatcacgatc aaaaggacaa
    14041 agtcttcgga ctttgtcctt agcttgtaga gaaaacgacg ttttttctac aagctttttt
    14101 gttttataca gtttctttag atattcatca ggtttcagat gcagaaaaag cgctcccaca
    14161 tgcctagccc tgcttggcta ggtatgtggc aatcttcttc atgttctggc atgcggctgt
    14221 gaggagaact tgttcactca catttcgttt tcccctcaac ctgcaatagc gaagcccatg
    14281 cagctgtttt gaatctgcaa agcttcgctc tattttttct tttctttttt tgtagaggtt
    14341 ttttcctgaa acagacaagc gattttgtct gaccttttct gtaagatctt ccaatacatg
    14401 acgagta
//
