LOCUS       c00080_gnlPro..        13025 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FJJECKHO_81.
ACCESSION   c00080_gnlPro..
VERSION     c00080_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 19:47:16
            Original ID  :: gnl|Prokka|FJJECKHO_81
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13025
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13025
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[977:3025]"
                     /cutoff="10000"
                     /detection_rule="(Flavoprotein and Phea_decarb and not
                     ubi_syn)"
                     /neighbourhood="10000"
                     /product="hydroxybenzoate2phenol"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      978..3025
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Flavoprotein and Phea_decarb and not
                     ubi_syn)"
                     /neighbourhood="10000"
                     /product="hydroxybenzoate2phenol"
                     /protocluster_number="1"
     cand_cluster    1..13025
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Flavoprotein and Phea_decarb and not
                     ubi_syn)"
                     /kind="single"
                     /product="hydroxybenzoate2phenol"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13025
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="hydroxybenzoate2phenol"
                     /region_number="1"
                     /rules="(Flavoprotein and Phea_decarb and not ubi_syn)"
                     /tool="gutsmash"
     CDS             complement(3..143)
                     /locus_tag="ctg80_1"
                     /transl_table=11
                     /translation="MFHTRNSSQNTAEFVLLDQLVEEDHLLRKIDKHIDFSFIIEKVKP
                     YY"
     CDS             complement(274..495)
                     /locus_tag="ctg80_2"
                     /transl_table=11
                     /translation="MVEGSSYYVKLECAPLPPLKDAEYERDRFSCRIVSVKEDVAKYAD
                     LTSGVRIQLHSAEEVLGRWEKTLEDLKR"
     CDS             complement(468..719)
                     /locus_tag="ctg80_3"
                     /transl_table=11
                     /translation="MSDRLFELLDGSCLNEKQHEAFVLQTVSEDGWPHAAMISAGEIIA
                     LSRTDIRIALWKNTMTSANILRTGTAQFTAWWKGAAIM"
     CDS             complement(734..919)
                     /locus_tag="ctg80_4"
                     /transl_table=11
                     /translation="MSKSPVEGAWEVYQCQTCFFTWRSCEPESITNPKKYNPAFKIDPK
                     ETETAIEVPAVPERKA"
     CDS             complement(978..2399)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydroxybenzoate2phenol: Phea_decarb"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg80_5"
                     /sec_met_domain="Phea_decarb (E-value: 1.9e-247, bitscore:
                     810.7, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAYQDFREFLAALEKEGQLLTVNEEVKPEPDLGAAARAASNLGDK
                     SPALLFNNIYGYHNAQIAMNVIGSWPNHAMMLGMPKDTPVKEQFFEFAKRYDQFPMPVK
                     REETAPFHENEITEDINLFDILPLFRINQGDGGYYLDKACVISRDLEDPDNFGKQNVGI
                     YRMQVKGKDRLGIQPVPQHDIAIHLRQAEERGINLPVTIALGCEPVITTAASTPLLYDQ
                     SEYEMAGAIQGEPYRIVKSKLSDLDVPWGAEVVLEGEIIAGEREYEGPFGEFTGHYSGG
                     RSMPIIKIKRVYHRNNPIFEHLYLGMPWTECDYMIGINTCVPLYQQLKEAYPNEIVAVN
                     AMYTHGLIAIVSTKTRYGGFAKAVGMRALTTPHGLGYCKMVIVVDEDVDPFNLPQVMWA
                     LSTKMHPKHDAVIIPDLSVLPLDPGSNPSGITHKMILDATTPVAPETRGHYSQPLDSPL
                     TTKEWEQKLMDLMNK"
     CDS             complement(2402..3025)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydroxybenzoate2phenol: Flavoprotein"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg80_6"
                     /sec_met_domain="Flavoprotein (E-value: 4.3e-30, bitscore:
                     94.9, seeds: 91, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGMKAEFKRKGGGKVKLVVGMTGATGAIFGVRLLQWLKAAGVET
                     HLVVSPWANVTIKHETGYTLQEVEQLATYTYSHKDQAAAISSGSFDTDGMIVAPCSMKS
                     LASIRTGMADNLLTRAADVMLKERKKLVLLTRETPLNQIHLENMLALTKMGTIILPPMP
                     AFYNQPSSLEEMVDHIVFRTLDQFGIRLPEAKRWNGIEKQKGGA"
     CDS             3085..3978
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     67.3; E-value: 2.9e-21)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg80_7"
                     /sec_met_domain="LysR_substrate (E-value: 2.4e-32,
                     bitscore: 102.3, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 9e-22, bitscore: 67.3,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRRRFLLDIRQPRYFITIAQEQKITSAAKKLHMAQPPLSRQLKQ
                     LEDELGVVLFDRNKKKQMTLTYEGAVFLKRAKEILHRFEDAVIEVQELKEEVAGTLAVG
                     STIYCAALMLEKVTQIKERYPHLTFNIWENEPATLLELLESRQIDAAVTTTLIKSDTVQ
                     FKQLDDIPCVLVLSDEAGYPCGDTIKMEDIPSFPLILLRPVNGKGVYNQVMNEFHRLNL
                     EPRIVCECHDSATLLSLVSSGFGASILPVTMIPVHMRNHVHTVHIENNPFIMTPAVMWR
                     TDSYLPKPAQQFLDLF"
     CDS             4094..4900
                     /locus_tag="ctg80_8"
                     /transl_table=11
                     /translation="MKKALLALFMVVSIAALAACGAGNDNQSKDNAKDGDLWASIKKKG
                     VLTVGTEGTYEPFTYHDKDTDKLTGYDVEVITEVAKRLGLKVDFKETQWDSMFAGLNSK
                     RFDVIANQVGKTDREDKYDFSDKYTTSRAVVVTKKDNNDIKSEADVKGKTSAQSLTSNY
                     NKLATNAGAKVEGVEGMAQALQMIQQGRVDMTYNDKLAVLNYLKTSGNKNVKIAFETGD
                     PQSTYFTFRKGSGEVVDQVNKALKEMKEDGTLSKISKKWFGEDVSK"
     CDS             4887..5591
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 90; E-value: 5.2e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg80_9"
                     /sec_met_domain="BPD_transp_1 (E-value: 1.6e-28, bitscore:
                     90.0, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFLNNLPALTLGTAIPWDLVQQSFWPILSGGIYYTIPLTILSFIF
                     GMILALITALARMSKVRPLRWVFSVYVSAIRGTPLLVQLFIIFYLFPAFNVTLDPFPSA
                     VIAFSLNVGAYASEIIRASILSVPKGQWEAGYTIGMTHQKTLFRVILPQAFRVSIPPLS
                     NTFISLIKDTSLASQILVAELFRKAQEIGARNLDQILVIYIEAAFIYWIICFLLSLVQH
                     VIERRLDRYVAK"
     CDS             5605..6348
                     /locus_tag="ctg80_10"
                     /transl_table=11
                     /translation="MLTVKGLNKSFGENEILKKIDMKIEKGKVIAILGPSGSGKTTLLR
                     CLNALEIPNRGELAFDDFSIDFSKKVKQADILKLRRKSGMVFQAYHLFPHRTALENVME
                     GPVQVQKRNKEEVRKEAIQLLDKVGLKDKMDLYPFQLSGGQQQRVGIARALAIQPELML
                     FDEPTSALDPELVGEVLKVIKDLANEGWTMVVVTHEIKFAQEVADEVIFIDGGVIVEQG
                     PPEQIFSAPKEERTQRFLNRILNPL"
     CDS             6669..7316
                     /locus_tag="ctg80_11"
                     /transl_table=11
                     /translation="VKQELVLRWTFYFAGLIILAFGVSLTIEGKALGISPWDAFHYSLF
                     QHFGLTVGQWSIIIGALIVGFTSLFTRAWPKIGALLNMVLIGVFIDFFNFILPAPSTYT
                     GSIIVFSLGVVLIGYGVGVYVSAGLGAGPRDSLMMLITEKTGWNVQWVRNGMELTILFA
                     AWGMGGPIGFGTILTAILTGLILRFSLPQSIQLLNYAVARRTAAVKASPPVH"
     CDS             7421..8095
                     /locus_tag="ctg80_12"
                     /transl_table=11
                     /translation="MKIYGIYMDRPLSQEENERFMSFISPEKREKCRRFYHKEDAHRTL
                     LGDVLVRSVISRQYQLDKSDIRFSTQEYGKPCIPDLPDAHFNISHSGRWVIGAFDSQPI
                     GIDIEKTKPISLEIAKRFFSKTEYSDLLAKDKDEQTDYFYHLWSMKESFIKQEGKGLSL
                     PLDSFSVRLHQDGQVSIELPDSHSPCYIKTYEVDPGYKMAVCAAHPDFPEDITIVSYEE
                     LL"
     CDS             complement(8090..9424)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg80_13"
                     /sec_met_domain="Aminotran_1_2 (E-value: 6.4e-24, bitscore:
                     75.0, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKYMSLVTRIEEMMQSTAYQEGDRLPSIRQMSARYQVSKSTVIR
                     ALQELEKRHLIYSVPKSGYYIVKKTGKSKSGQPGPIDFATSAPDPDVFPYLDFQHCINK
                     AIDTYKNDLFIYGTPKGLPSLIRVLRKLLANQQVFADERHIFITSGVQQALSLLCAMPF
                     PNGKEKIAIEQPGYHLMVEQLETLGIPAIGVKRTEEGLDIAEVERLFQTESIKFFYTMP
                     RFHNPLGCSLSERDKQELVRLAEAYDVYLVEDDYLGDLEENKKADPLYAYDLSSHVIYL
                     KSFSKMMFPGLRVGAAVLPEALTDTFYAYKKLNDIDCSMISQAALEIYLKSGMYGRHKE
                     KIRDSYKERSLKLHQAIQTHRQLGSGRFTFSSGQAPCMHTHLVLPQDLPASRVIHRLKK
                     QGVLLEAIDRHYLSDYQKENLLKINISNVKTEDIERGVKLLMSHL"
     CDS             9548..10486
                     /locus_tag="ctg80_14"
                     /transl_table=11
                     /translation="MVKHQQASAYTAAILYSFIIGLSFLFVKIALQTAEPFDILAHRFT
                     LAFAAATVPILFGWVKLSIRVKDVIAILPLALLYPALFFSFQAFGLVYSSSSEAGIIQA
                     AIPIFTMVFAAYVLKERPTWTQKGFTVLSVAGVMFIFVMKGVDVESASLKGSLLILLSA
                     LSSAMYNTAARKMTQRFKLTELTYIMSAIGFVVFNAIALVRHGAAGTVFTYFLPFREPG
                     FVLAIVYLGVLSSLVTSILSNYTLSRIEAFKMSAFNHVSTIVTMISGVVILNESLAWYH
                     LAGAVCIMIGVVGSNINLEKKTKRPGIPAKK"
     CDS             10540..11097
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) YcxB"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg80_15"
                     /sec_met_domain="YcxB (E-value: 3.2e-14, bitscore: 42.8,
                     seeds: 189, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQYASESINLPGEISFKDVREIFFYQIAKISCFYFLLFCAIFAA
                     VNFINGWPRIVYGSDALNLFMNSMLIIVMSVLFTLLLLLLLYVKFSRAYKKNERMKSKR
                     TYTLNQEGIRICSKKYDLIFNWDEITAVFEYKNIFRVNTSSGQYIAIPKRFFHSEVEMN
                     RFKEIILKNTETKKLKFKKDQH"
     CDS             complement(11112..12338)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 120.7; E-value: 2.3e-37)"
                     /gene_kind="transport"
                     /locus_tag="ctg80_16"
                     /sec_met_domain="MFS_1 (E-value: 6.9e-38, bitscore: 120.7,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTSPRMKWFVLLFTFVFAIGMNSFRNSFQFFMLPMADAFHADRS
                     LISVSVSIFMITTGIVQFFVGFFIDRFSVRKIMALGAVCISASFLVLPYSPNVHVFSAI
                     YGVLGGIGYSCAVGVTTQYFISRWFDTHKGLALAILTNANSAGLLLLSPIWAEAPYHAG
                     WQSTYTILGIVMAAVLLPLFVIGMKHPPYAQAESVKKSYDWRGFWNVMKQSRLIHILYF
                     GVCTCGFTMGIIDAHLVPMLKDAHVSHVNGMMAAFGAFIIIGGLLAGWLSDLLGSRSVM
                     LSILFFIRLLSLICLLIPILGIHHSDLWYFGFILLFGLSYTGVIPLTAASISESYQTGL
                     IGSLLGINFFIHQVAGALSVYAGGLFFDMTHGYLLIVAVCIVFVGLSAVIELVPFLDKQ
                     KAKETHQSI"
ORIGIN
        1 ctgtagtaag gtttcacctt ttcaatgatg aaagagaagt ctatgtgttt atcaattttc
       61 cgaagcaggt gatcctcttc aacgagttgg tcaagcagaa caaattcggc tgtgttttga
      121 gaagagtttc ttgtgtggaa catgagaaag acaccgtcct tttaagtctt tcttttattt
      181 tattacagaa gaatggatat tttaaggaaa aataaaggct gtcgagattt tctcgacagc
      241 ctgagcctga cgcatggcgt caggctatcg atattaccgt tttaaatctt ccagggtctt
      301 ttcccatctg cccagcacct cttcagcgct gtgaagctgt atacggacac ctgaagtcaa
      361 atcagcgtat ttcgcaacgt cctccttcac tgaaacaatg cggcaggaaa aacggtctct
      421 ttcatattcg gcatctttca aaggcggtaa aggcgcgcat tcaagcttta cataatagct
      481 gctcccttcc accatgccgt gaactgtgct gttcctgtgc gaaggatgtt ggccgaagtc
      541 attgtgtttt tccacagagc gattcggata tcagttcggc tcagcgcgat aatttcacct
      601 gcactgatca tagcggcatg cggccagcca tcctctgata ctgtttgcag aacgaaggcc
      661 tcatgctgct tctcattcag gcagctcccg tcaagcagct caaagagacg gtctgacata
      721 ctgttcacgc ggatcaagcc tttcgttccg gcaccgccgg aacttcaatt gctgtttctg
      781 tttcctttgg atcaatttta aacgctggat tgtatttttt gggatttgta atgctttccg
      841 gttcacagga tctccatgta aaaaagcatg tttggcactg ataaacttcc catgcgcctt
      901 ctacaggcga tttgctcatg acttctccct tttttgagtc gcatcgagga catgtatgca
      961 tttcgaacat cctttcctta tttattcatt aaatccatta gtttttgttc ccattctttc
     1021 gttgttagcg gagaatcaag cggctgtgaa taatggcctc ttgtttccgg cgcaaccggt
     1081 gtagtggcgt cgagaatcat tttgtgagtg attcctgatg gattggatcc cggatcaagc
     1141 ggcaggacag ataagtccgg aatgatgacc gcatcgtgtt tcggatgcat tttggtcgaa
     1201 agcgcccaca tgacctgcgg aaggttgaat ggatcgacat cctcatcaac gacaatgacc
     1261 attttgcagt agccgagtcc gtgcggcgtt gtgagtgcgc gcatgccgac cgctttcgca
     1321 aatccgccat agcgggtttt tgtggaaaca atcgcgatta aaccgtgtgt gtacatggcg
     1381 ttcactgcca caatttcgtt cgggtacgct tcttttaact gctgataaag cggcacgcat
     1441 gtgttaatgc caatcatgta atcgcattct gtccaaggca tgcctaagta taaatgttca
     1501 aagatcggat tgtttctgtg atagacgcgt ttaattttga taatcggcat gctgcgtccg
     1561 ccggaataat ggcctgtgaa ttcaccgaac ggcccttcat attcgcgctc tccggcaata
     1621 atctcacctt caagcaccac ttcagcaccc caaggaacat caagatcaga cagctttgat
     1681 ttgacgatgc gatatggttc gccttgaatc gcgcctgcca tttcgtattc tgattgatca
     1741 tagagaagcg gagtcgatgc cgccgttgta atgaccggct cacagccgag cgcaatggtg
     1801 accggaagat tgatgccgcg ttcttcagct tggcgcagat ggattgcaat atcgtgctgc
     1861 gggacaggct gaatgccgag gcggtctttt cctttgacct gcattctgta aatgccgaca
     1921 ttttgtttgc cgaagttgtc agggtcttca agatcacggg agatgacaca cgctttgtct
     1981 aaatagtagc ctccatcacc ttggttaatt ctgaaaagag gcagtatatc gaacaaattg
     2041 atatcttctg tgatttcatt ttcatgaaat ggtgctgttt cctcacgttt gaccggcatc
     2101 ggaaactggt cataacgctt tgcgaattca aaaaactgtt cttttaccgg tgtgtctttc
     2161 ggcatgccca gcatcatggc atggtttggc caagagccga tgacattcat cgcaatttgg
     2221 gcgttatgat agccgtaaat gttgttaaat aagagcgcgg ggcttttatc gccaagattg
     2281 ctggctgccc gtgcggcggc ccctaaatcc ggttccggct ttacctcttc attcactgta
     2341 agcagctgtc cttctttttc aagggcagcg agaaattctc tgaaatcttg ataagccatg
     2401 atcaagctcc tcctttttgt ttttcaatcc cattccagcg cttcgcttca ggaagccgaa
     2461 tgccgaattg gtccaacgtt ctaaaaacaa tatggtcaac catttcctct aagctgctcg
     2521 gctgattata aaatgccggc atcggaggaa gaatgattgt acccattttc gtaagcgcta
     2581 gcatattttc gagatgaatt tggttcaaag gcgtctctct cgttaagagg acgagttttt
     2641 ttctctcctt gagcatgaca tccgccgcac gtgtcagcag attatccgcc atgccggtgc
     2701 gaatgcttgc gagagatttc atgctgcacg gcgcaacaat cattccatcg gtatcaaacg
     2761 acccgcttga aatggctgcc gcctgatcct tatgtgagta agtgtatgtg gccagttgtt
     2821 ctacttcttg taaggtatag cctgtttcgt gtttgatcgt gacgtttgcc caaggagaca
     2881 caacgagatg ggtttccact ccggcggcct tcagccactg cagcagcctg accccaaaaa
     2941 tggcccctgt tgcccctgtc attccgacaa cgagtttcac tttgccccct cctttacgct
     3001 tgaattctgc tttcattcca atcatactcc tgatatatcc atatgaaaaa tatctattaa
     3061 atctatattt aatacctaaa aggtatgata aggaggcgct ttcttttgga tattcgccag
     3121 cctcgatact tcattaccat tgcccaagaa cagaaaatta cgtccgcagc caaaaagctt
     3181 cacatggcgc agccgccttt aagcaggcag ctcaaacagc tggaggacga gcttggtgtt
     3241 gttctgtttg accggaacaa gaaaaaacaa atgactctta catatgaagg agctgttttt
     3301 ctaaaaagag caaaagagat tctgcatagg tttgaagatg cagtcattga ggtacaggag
     3361 ctgaaggagg aagtagccgg tacacttgcc gtgggatcaa cgatttattg cgcggctctg
     3421 atgcttgaaa aagtaacaca gatcaaagag agataccccc atctcacctt taatatttgg
     3481 gaaaatgagc ccgcgacact gttagagctg ctggaaagcc ggcaaatcga tgcggcggtc
     3541 acgacaacac tgatcaaaag tgacacagta caattcaagc agcttgatga cattccatgt
     3601 gtgctcgtgc tttcagatga agccggatat ccgtgcggag acaccattaa gatggaggac
     3661 attccttcat ttccgctgat cctgctgcgg cctgtcaacg gaaaaggcgt ctataatcag
     3721 gtcatgaatg aatttcatcg tttgaacctg gagccgcgca ttgtttgtga atgccacgac
     3781 tctgcaactt tgctcagcct cgtgtcatcc ggattcggcg cgtctatttt gcctgtcaca
     3841 atgattcccg ttcatatgag aaatcacgtt cacaccgtcc atatcgaaaa taatcccttc
     3901 attatgacac cggctgtcat gtggagaacg gacagttatt tgcctaaacc ggcacagcaa
     3961 tttttggatt tattttaaaa gattttgcct tatgaaaacc aattacttga ctcatactaa
     4021 aaaaaagtta tcctttagat ttgtaagcta tttttttatt tcaataaaat caaccagaaa
     4081 agtggggaat aagatgaaaa aagcattatt ggctttattc atggtcgtaa gtattgcagc
     4141 tcttgcagct tgcggagcag gaaatgacaa tcagtcaaaa gataatgcca aagatggcga
     4201 tctttgggct tcaattaaga aaaaaggtgt gctcacagtc ggaacggaag gaacatatga
     4261 gccgttcact taccacgaca aagacactga taaactgact ggctatgatg tcgaagttat
     4321 cacagaagtc gcaaaacgcc tcgggcttaa agtcgacttt aaggaaacac aatgggacag
     4381 catgtttgcc ggcctgaatt ccaaacggtt tgacgtcatt gccaaccaag tcggaaaaac
     4441 agatcgtgaa gacaaatatg atttctcaga taaatacaca acatcaagag ccgttgtcgt
     4501 tacgaaaaaa gacaacaacg atattaagtc agaagcagat gtaaaaggaa aaacatcagc
     4561 tcaatcactg acaagcaact acaacaaatt agctacaaat gccggcgcta aagtagaagg
     4621 cgttgaaggt atggcgcagg cccttcaaat gatccagcaa ggccgcgtcg atatgacata
     4681 caacgataaa cttgccgtat tgaactactt aaaaacatct ggcaataaaa acgtgaaaat
     4741 cgcgtttgaa acaggtgatc ctcagtcaac atatttcacg ttccgtaaag gaagcggcga
     4801 ggttgttgat caagtcaaca aagcattaaa agaaatgaaa gaggacggga ctctttctaa
     4861 aatttctaaa aaatggttcg gcgaagatgt ttctaaataa tctgccggca ttgacgcttg
     4921 gcacggcgat cccgtgggat ctggtgcagc agtcattctg gccgatactt tcagggggaa
     4981 tctactatac gattcccctt acgattcttt cctttatatt cggaatgatc ctggcgctga
     5041 ttacggcgct tgccagaatg tcgaaagtga gacctttgag atgggtgttc agcgtatacg
     5101 tatccgcaat acgcggcact cctcttctcg ttcaattgtt catcattttc tatctgttcc
     5161 cggcctttaa cgtcacatta gatccatttc caagcgcagt tatcgccttt tcattaaacg
     5221 tcggcgccta tgcatctgaa atcattcggg catctatttt atccgtgccg aaagggcaat
     5281 gggaagccgg ctacacaatt ggcatgacac atcaaaaaac gctgttccgc gtcattttgc
     5341 cgcaggcgtt tcgtgtgtcg atcccgccat tatccaatac ctttatcagc ctgattaaag
     5401 atacatccct cgcctctcaa attctggtcg ctgagctgtt cagaaaagcc caggaaatcg
     5461 gcgcgcggaa tcttgatcaa attttagtga tctatattga agcagccttt atttattgga
     5521 ttatctgctt cctgctttca ctcgtccagc atgtcatcga acggcgtctt gaccgctacg
     5581 tggccaaata aggaggttct gagtatgctt accgttaaag gattaaacaa atcattcggt
     5641 gaaaatgaaa ttttaaaaaa gatagatatg aagattgaaa aaggaaaagt catcgccata
     5701 cttgggcctt caggttcagg gaaaacgacg ctgctccgct gcctgaacgc tctggagatc
     5761 ccaaatcgcg gagagcttgc atttgatgat ttctccatcg atttctccaa aaaggtgaaa
     5821 caggcggata tcctaaagct tcgccgaaaa tccggaatgg tgtttcaggc gtatcacctg
     5881 ttcccgcacc gcacagccct cgaaaacgtg atggagggcc ctgttcaggt gcaaaaacgg
     5941 aacaaagagg aagtcagaaa agaagcgatt cagcttcttg ataaagtcgg attgaaggac
     6001 aaaatggatt tatatccatt ccagctttcc ggcggacagc agcagcgcgt cggcatcgcc
     6061 cgcgcactgg cgattcagcc tgagctcatg ctgtttgacg aaccgacctc agcgcttgat
     6121 cccgagcttg tcggagaggt gctgaaggtt atcaaggact tggccaatga aggctggacc
     6181 atggtcgtcg tgacccacga aatcaagttc gcgcaggaag ttgcggatga agtcatcttc
     6241 atcgacggcg gcgttatcgt ggagcaggga ccgccggagc aaattttctc cgcaccaaaa
     6301 gaagagcgga cacagcggtt cttgaaccgg attttgaacc cgctgtaata agaaaaacag
     6361 ggcgtcagcg ccctgtttca gattattgac aaaatcctaa aacgattttc gttttaggat
     6421 tttgtcattt tcagcgtgat tgaaaacctt tgaagtctag gaagggcgag cattggagca
     6481 catcgaatgt taaattcgtg agcaccgaag cgcaggcctg acaacgaatg caagggtttg
     6541 ccaacacgct gaaacagggc gccggcggcg gccctgtttt tttgttgagc ccctttcgcc
     6601 tattccgccc ttctgtcaga tgtgctacaa tgacaatcga ctgattttta cgaaagaagg
     6661 gacctcacgt gaagcaagaa cttgttctgc gctggacatt ttattttgcc ggtttgatca
     6721 ttttggcttt tggtgtatcc ctgacgatag aaggaaaagc actcggcatt agtccgtggg
     6781 atgcatttca ttacagcctg tttcagcact tcgggcttac cgtcggccag tggtccatca
     6841 ttattggagc gctcatcgtc ggattcacgt cattgtttac gagagcttgg ccaaaaattg
     6901 gggccctcct gaatatggtg ctcattggtg tatttataga ttttttcaat ttcattctgc
     6961 ctgccccctc gacctacaca ggctcgatca tcgtcttctc tctaggcgtg gtgctgattg
     7021 gttacggcgt cggtgtttat gtatcagcag gccttggcgc ggggccgcgt gattcactga
     7081 tgatgctgat tacagaaaaa accggctgga atgtgcaatg ggtgcggaac ggcatggaat
     7141 taaccatttt gtttgcggca tggggcatgg gcggaccgat cggttttggc accattttga
     7201 ccgccatcct caccggactc attctgcgtt tttcattgcc gcagtcaatc cagttgctga
     7261 attatgctgt ggcaaggcgg acagccgctg tgaaagcatc tccgcctgta cactaaaaca
     7321 aagccgcctt ggctttgttt ttttattttc tcctctatat gagtcttgtg gaagtatgat
     7381 aggatggttt tgacaatctt ttgcagacgg aggatctaga atgaagattt acggaattta
     7441 tatggaccgc ccgctttcac aggaagaaaa tgaacggttc atgtctttca tatcacctga
     7501 aaaacgggag aaatgccgga gattttatca taaagaagat gctcaccgca ccctgctggg
     7561 agatgtgctc gttcgctcag tcataagcag gcagtatcag ttggacaaat ccgatatccg
     7621 cttcagcacg caggaatacg ggaagccgtg catccctgat cttcccgacg ctcatttcaa
     7681 catttctcac tccggccgct gggtcattgg tgcgtttgat tcacagccga tcggcataga
     7741 tatcgaaaaa acgaaaccga tcagccttga gatcgccaag cgcttctttt caaaaacaga
     7801 gtacagcgac cttttagcaa aagacaagga cgagcagaca gactattttt atcatctatg
     7861 gtcaatgaaa gaaagcttta tcaaacagga aggcaaaggc ttatcgcttc cgcttgattc
     7921 cttttcagtg cgcctgcacc aggacggaca agtatccatt gagcttccgg acagccattc
     7981 cccatgctat atcaaaacgt atgaggtcga tcccggctac aaaatggctg tatgcgccgc
     8041 acaccctgat ttccccgagg atatcacaat agtctcgtac gaagagcttt tataaatggc
     8101 tcatcaacag cttgacaccg cgctcaatat cttccgtttt cacattggaa atattgattt
     8161 ttaatagatt ttctttctga taatctgata aataatgacg gtctatcgcc tcaaggagaa
     8221 ccccttgttt tttcagtcta tgaatcactc ttgaggcggg cagatcctga ggaagcacca
     8281 ggtgggtgtg catgcagggt gcctgcccgc tggagaacgt aaagcggccg cttcccagct
     8341 gcctgtgtgt ttgaatggct tgatgaagct tcagcgaccg ctctttataa gaatctctga
     8401 ttttctcctt atgcctgccg tacataccgc ttttcaggta aatctccaat gccgcttgag
     8461 aaatcatcga acagtcgatg tcgttcagct ttttgtacgc atagaacgtg tcagtcagcg
     8521 cttcgggcaa aacagccgcc cccacgcgaa ggccggggaa catcattttc gagaagcttt
     8581 tcaaatagat gacatgtgag gacagatcat atgcgtacag cggatctgcc tttttatttt
     8641 cctccagatc accgaggtaa tcatcctcaa cgagatagac atcatacgct tctgccagtc
     8701 tcacaagctc ctgtttatca cgctctgaca atgagcagcc aagcgggtta tggaagcgcg
     8761 gcatcgtata aaaaaattta atcgattctg tttgaaataa ccgctcaacc tcggctatat
     8821 caagtccctc ttccgttcgt ttcaccccga tggcgggaat cccaagcgtc tcaagctgtt
     8881 cgaccatcaa atggtagccc ggctgttcaa tggcgatctt ctctttccca tttgggaacg
     8941 gcatggcaca aagcagagat aacgcctgct ggacacctga tgtaatgaaa atatgccgtt
     9001 catccgcaaa tacctgttga ttggccaaga gctttcggag tacacggatg agtgatggaa
     9061 gcccctttgg cgtcccataa ataaacaaat cgtttttgta tgtatcaatc gctttgttga
     9121 tacagtgctg aaaatcaaga tacggaaaca catctggatc cggcgcagat gtggcaaagt
     9181 cgatggggcc aggctgcccg ctttttgatt tccctgtctt tttcacaata taatagccgc
     9241 ttttcggaac agaatagata aggtggcgct tttccagctc ctgcagcgcg cggatcactg
     9301 tgcttttgct gacttggtag cgggcggaca tctgacggat agatggaagc ctgtctcctt
     9361 cttgataggc ggtgctttgc atcatctcct ctatcctcgt tactagactc atatatttct
     9421 ccatgccttc tccccctgtt ttgtaccggt acagttcatt gtttttctca ttgtaccgtt
     9481 ctgaccgcgg tcatacaata aagagagcga ccggcgctgc aattcaggta aaggagcact
     9541 tcccattatg gttaaacatc agcaagcctc cgcttatacg gcggctatct tatattcgtt
     9601 cattatcggt ttatcctttc tattcgtaaa aatcgcactg caaacagcag agccgtttga
     9661 tattttggcg catcggttca cccttgcgtt tgctgcggcg actgtaccga tcttattcgg
     9721 ctgggtaaag ctatcaatcc gtgtaaagga cgtcattgcc attttgccgc tcgccctgct
     9781 gtatcccgcg ttatttttca gctttcaggc attcggcctt gtgtactcgt cctcctctga
     9841 agcgggaatt attcaggcag ccattccgat tttcacgatg gtctttgccg cttatgtttt
     9901 aaaggaacgc ccaacgtgga cgcaaaaagg gttcacggtt ttatccgttg ccggcgtcat
     9961 gtttattttt gtgatgaaag gcgttgacgt ggaatcagcc agcttaaaag ggtctttgct
    10021 gatcctattg tccgctttgt cttcagcgat gtacaatact gctgccagaa aaatgacgca
    10081 gcggttcaag ctgaccgagc tcacctacat catgtcagcc atcggctttg tcgtcttcaa
    10141 cgccatcgcc cttgtgcgtc acggagcggc gggaacagtc ttcacttatt ttctgccgtt
    10201 ccgggagcca ggcttcgttc tcgccattgt gtatttgggc gtgctgtctt cactcgtcac
    10261 ttcaattctg tctaactata cgctgtcgcg aattgaggcg tttaaaatga gtgcttttaa
    10321 tcatgtatct accattgtga cgatgatttc aggagttgtg attctcaacg aaagcctggc
    10381 ctggtatcat cttgccgggg ctgtttgtat tatgattggc gtggtgggga gcaatatcaa
    10441 tctggagaaa aaaacaaagc gccctggtat acctgcaaaa aaatgagaaa ttatgctaga
    10501 ctgaaaggaa aaacatggtt agaggtgtaa gtttatcgta tgattcaata tgctagtgaa
    10561 agtatcaatc ttccaggaga aatctctttt aaggatgtaa gagaaatctt tttttatcaa
    10621 atcgcaaaaa tatcatgctt ttactttctg ttgttttgcg ccatatttgc tgcagttaac
    10681 ttcattaacg gatggccccg tatcgtttat ggcagtgacg cgcttaactt gtttatgaac
    10741 agtatgttga ttatcgtgat gtccgttctg tttacactgc tgctcctcct tcttctatat
    10801 gtgaagtttt ccagagcata caagaagaac gaacggatga aatctaaaag aacatatact
    10861 ctgaaccaag aaggaattcg tatatgttct aaaaaatatg acctcatttt caattgggat
    10921 gaaatcacgg ctgttttcga atataaaaat atcttcaggg tcaatacatc aagtggccaa
    10981 tatattgcga tcccaaaacg tttttttcat tccgaagtgg agatgaacag attcaaggag
    11041 attatcctta aaaataccga aacaaaaaaa ctcaaattta aaaaggatca gcattgacag
    11101 tgctgatcct tttatattga ttggtgggtt tcttttgcct tttgtttatc taaaaacggc
    11161 accagctcta ttactgccga taaacccaca aacacgatgc acacagcgac aatcagcaaa
    11221 taaccatgag tcatgtcaaa aaacaaaccg cccgcataca cgctgagagc tccggcaacc
    11281 tgatggataa agaaattgat gcctaacagc gatccgatca atcctgtttg atagctttcc
    11341 gaaattgacg ccgcggtcag cgggatcacg cctgtgtaac tgagcccgaa taacaggata
    11401 aacccgaagt accaaaggtc gctgtgatga attccgagaa tgggaatgag caggcaaatg
    11461 aggctgagca gccgaatgaa aaataagatg gatagcatga cgcttctgct gccgaggaga
    11521 tcggacagcc agcctgccaa taatccgcca atgataataa acgccccgaa cgcggccatc
    11581 attccgttga catgagagac atgtgcatcc ttcagcatcg gaacgagatg agcatcaatg
    11641 attcccatcg taaatccgca agtacacacg ccgaagtaca ggatatgaat gaggcgggat
    11701 tgcttcatca cgttccaaaa cccccgccaa tcataagatt ttttcacaga ctccgcttgc
    11761 gcatacggcg ggtgcttcat cccaatgacg aagagcggca gcagaacagc cgccatgacg
    11821 attcccaaaa tcgtataggt gctctgccag ccggcatgat acggagcctc agcccaaatg
    11881 ggcgagagaa gcagcaggcc cgcagagttg gcattggtca aaatagcaag cgccagacct
    11941 ttgtgtgtgt caaaccaacg gctgatgaaa tactgggtcg tcacgccgac cgcgcaggaa
    12001 tagccgattc cgccaagcac accgtaaatg gcggaaaaca catgaacatt cggtgaataa
    12061 ggaagcacca aaaagcttgc gctgatgcag acagctccaa gcgccataat ttttctgaca
    12121 ctgaaacggt cgatgaaaaa accgacaaaa aactggacga tgccggttgt gatcataaaa
    12181 atgctgacag aaaccgaaat cagcgacctg tcggcatgga aggcatccgc cattggcagc
    12241 ataaaaaatt gaaaggaatt tctgaatgag ttcattccga tggcgaaaac aaacgtaaac
    12301 agcaatacaa accatttcat cctgggagac gtgcgcatgt ttcgacctgc ctttatttga
    12361 gtatttcgac tattatacca tgcgaaaatt ggcattcaac acaaaaaaaa gcggaacagc
    12421 cgaagctgtc cgcttttgat cacggttgaa tgatcggatg ctgattcaag atcgcaaaaa
    12481 tccgttctgc gacttcttcc gtttgtgaca gcaggaacat gtgtcctccg tcaaattgat
    12541 ggaatgtgat gtcttttgcc cacttcttcc agccttccgc atctcgtatg cattttttat
    12601 catcaagccc gttaaagaca tgaacaggcg actggatctg ggccagatcg taaagctcaa
    12661 attgttcaag agcccggtaa tctgatcgga aagaaggcag gaaaaaggac atgacctcct
    12721 tattttcaac aagctctgcg ggcattccgc ctaattggat aatatgatcg agaaactgat
    12781 catcaggcag gtgggacact ttcttccggt gaatatgagg cggctggatt gcagaaatga
    12841 taaccgcctg cggaaagatg ccctcacgct caagcttttg cgccagcctg aaggtgatca
    12901 ttccgcccat actgtgtccg aacagcacaa acggccgatc agggcgaagg ttcagttctt
    12961 gcttgtacaa atctgtcagc tcttcgagat cctcaatggc tgacgtttga ttcgtgccgt
    13021 gtccc
//
