LOCUS       gnlProkkaBILODBNM_74    1875 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BILODBNM_74.
ACCESSION   gnlProkkaBILODBNM_74
VERSION     gnlProkkaBILODBNM_74
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 19:54:28
            Original ID  :: gnl|Prokka|BILODBNM_74
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 1875
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..1875
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[1:1873]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2..1873
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..1875
                     /SMILES="NC(CC(C)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..1875
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             2..1873
                     /NRPS_PKS="Domain: AMP-binding (1-383). E-value: 7.3e-105.
                     Score: 342.7. Matches aSDomain:
                     nrpspksdomains_ctg74_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (488-556). E-value: 3.2e-28. Score:
                     89.6. Matches aSDomain: nrpspksdomains_ctg74_1_PCP.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     335.6; E-value: 6.7e-102)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg74_1"
                     /sec_met_domain="AMP-binding (E-value: 2.9e-116, bitscore:
                     374.5, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 5.6e-20, bitscore:
                     58.0, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 5.4e-20, bitscore:
                     57.7, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRHKDRRAVTYNGQSWTYGELNAKANRLARILMDCGISPDDRVGI
                     LTKPSLEMSAAVLGVLKAGAAFVPIDPDYPDQRIEYILQDSGAKLLLKQEGISVPDSFS
                     GDVILLDGSRTILSLPLDENDEENPETAVTAENLAYMIYTSGTTGQPKGVMVEHHALVN
                     LCFWHHDAFSMTAEDRSAKYAGFGFDASIWEMFPTWTIGAELHVIDEAIRLDIVRLNDY
                     FETNGVTITFLPTQLAEQFMELENTSLRVLLTGGDKLKRAVKKPYTLVNNYGPTENTVV
                     ATSAEIHPEEGSLSIGRAIANTRVYILGEGNQVQPEGVAGELCVAGRGLARGYLNREDE
                     TAKRFVADPFVPGERMYRTGDLVKWTGGGIEYIGRIDQQVKVRGYRIELSEIEVQLAQL
                     SEVQDAAVTAVKDKGGNTAIAAYVTPEIADIEALKSALKETLPDYMIPAFWVTLNELPV
                     TANGKVDRKALPEPDIEAGSGEYKAPTTDMEELLAGIWQDVLGMSEVGVTDNFFSLGGD
                     SIKGIQMASRLNQHGWKLEMKDLFQHPTIEELTQYVERAEGKQADQGPVEGEVILTPIQ
                     RWFFEKNFTNKHHWNQSVMLHAKKGFGPERVEKTLQALIEHHDALRMV"
     aSDomain        5..1150
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg74_1_AMP-binding.1"
                     /evalue="7.30E-105"
                     /label="ctg74_1_AMP-binding.1"
                     /locus_tag="ctg74_1"
                     /protein_end="383"
                     /protein_start="1"
                     /score="342.7"
                     /specificity="substrate consensus: Leu"
                     /tool="antismash"
                     /translation="RHKDRRAVTYNGQSWTYGELNAKANRLARILMDCGISPDDRVGIL
                     TKPSLEMSAAVLGVLKAGAAFVPIDPDYPDQRIEYILQDSGAKLLLKQEGISVPDSFSG
                     DVILLDGSRTILSLPLDENDEENPETAVTAENLAYMIYTSGTTGQPKGVMVEHHALVNL
                     CFWHHDAFSMTAEDRSAKYAGFGFDASIWEMFPTWTIGAELHVIDEAIRLDIVRLNDYF
                     ETNGVTITFLPTQLAEQFMELENTSLRVLLTGGDKLKRAVKKPYTLVNNYGPTENTVVA
                     TSAEIHPEEGSLSIGRAIANTRVYILGEGNQVQPEGVAGELCVAGRGLARGYLNREDET
                     AKRFVADPFVPGERMYRTGDLVKWTGGGIEYIGRIDQQVKVR"
     aSModule        5..1669
                     /complete
                     /domains="nrpspksdomains_ctg74_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg74_1_PCP.1"
                     /locus_tags="ctg74_1"
                     /monomer_pairings="Leu -> Leu"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       173..214
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg74_1_0001"
                     /evalue="5.50E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg74_1"
                     /protein_end="71"
                     /protein_start="57"
                     /score="19.4"
                     /tool="antismash"
                     /translation="LGVLKAGAAFVPID"
     CDS_motif       416..475
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg74_1_0002"
                     /evalue="4.20E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg74_1"
                     /protein_end="158"
                     /protein_start="138"
                     /score="34.5"
                     /tool="antismash"
                     /translation="AYMIYTSGTTGQPKGVMVEH"
     CDS_motif       815..844
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg74_1_0003"
                     /evalue="3.30E-03"
                     /label="NRPS-A_a5"
                     /locus_tag="ctg74_1"
                     /protein_end="281"
                     /protein_start="271"
                     /score="10.1"
                     /tool="antismash"
                     /translation="NYGPTENTVV"
     CDS_motif       947..1036
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg74_1_0004"
                     /evalue="2.40E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg74_1"
                     /protein_end="345"
                     /protein_start="315"
                     /score="51.8"
                     /tool="antismash"
                     /translation="PEGVAGELCVAGRGLARGYLNREDETAKRF"
     CDS_motif       1115..1180
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg74_1_0005"
                     /evalue="1.20E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg74_1"
                     /protein_end="393"
                     /protein_start="371"
                     /score="36.5"
                     /tool="antismash"
                     /translation="YIGRIDQQVKVRGYRIELSEIE"
     aSDomain        1466..1669
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg74_1_PCP.1"
                     /evalue="3.20E-28"
                     /label="ctg74_1_PCP.1"
                     /locus_tag="ctg74_1"
                     /protein_end="556"
                     /protein_start="488"
                     /score="89.6"
                     /tool="antismash"
                     /translation="EELLAGIWQDVLGMSEVGVTDNFFSLGGDSIKGIQMASRLNQHGW
                     KLEMKDLFQHPTIEELTQYVERA"
     CDS_motif       1715..1744
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg74_1_0006"
                     /evalue="3.90E-05"
                     /label="NRPS-E1"
                     /locus_tag="ctg74_1"
                     /protein_end="581"
                     /protein_start="571"
                     /score="16.3"
                     /tool="antismash"
                     /translation="LTPIQRWFFE"
ORIGIN
        1 ccagcgccac aaagaccgcc gggctgtcac ctacaacggc caatcttgga cgtacggcga
       61 gctgaatgcg aaggcaaacc gtctcgcgcg gattctgatg gactgcggca tcagcccgga
      121 tgaccgcgtc ggcattctca cgaagccgtc gcttgaaatg tccgccgcgg tgcttggcgt
      181 cttaaaagcg ggagcggcgt ttgtgccgat tgatcctgac tacccggatc agcggattga
      241 gtatatttta caggacagcg gcgcgaagct tctcttgaag caagaaggca tttcagtgcc
      301 ggatagcttc tcaggagacg ttattcttct cgacggaagc cgcacgattc taagcttgcc
      361 gcttgatgaa aacgatgagg aaaatccaga gacggctgta accgcggaga acttggcgta
      421 catgatttac acgtcaggaa cgaccggaca gccgaagggt gtcatggtcg agcaccatgc
      481 gcttgtgaac ctgtgcttct ggcaccacga cgcgttcagc atgacagcgg aggaccgcag
      541 tgcgaagtac gcgggcttcg ggttcgacgc ttccatttgg gagatgttcc cgacctggac
      601 gatcggcgcc gaacttcacg tcattgatga agcgatccgc ctcgatatcg tccgcctgaa
      661 cgattatttt gaaacgaacg gcgtaacgat cacgttcctg ccgacacagc ttgcggaaca
      721 gttcatggag cttgagaaca catcactccg tgttctcttg acaggcggag acaagctgaa
      781 gcgcgccgtg aaaaagccgt acacactcgt caacaactac gggccgacag aaaacacggt
      841 cgttgccaca agcgcagaaa tccatccgga ggaaggttcg ctttccatcg gacgggccat
      901 tgccaatacg agagtgtaca ttctcggcga gggcaatcag gtgcagccgg aaggcgtagc
      961 cggagagctt tgcgtggcgg gacgcggatt agcgcgaggc tatctgaatc gagaagacga
     1021 aaccgcgaag cggtttgtcg ctgatccgtt tgtgccgggt gagcgcatgt accgcaccgg
     1081 cgatttggtg aaatggacgg gcggcggcat cgaatacatc ggccggatcg accagcaggt
     1141 caaggtccgc ggctaccgga tcgagctttc agaaattgaa gtccagctcg cccagctttc
     1201 tgaggtgcag gatgcggcgg tgacagctgt caaagataaa ggaggcaaca cagcgatcgc
     1261 ggcgtatgtc acaccggaaa tagctgacat agaagcactg aaatcagcac tgaaggaaac
     1321 cctgccggat tacatgatcc cggcgttctg ggtgacgctg aacgagcttc cggttacggc
     1381 aaacggcaaa gtggaccgca aagccttgcc tgagccggac atcgaagcgg gaagcggaga
     1441 atacaaagcg ccgacgaccg acatggaaga gctgcttgcc ggcatctggc aggacgtgct
     1501 tggaatgtct gaagtcggtg tcaccgacaa tttcttctcg cttggcggag attccatcaa
     1561 aggaattcaa atggcgagcc gcttgaacca gcacggctgg aagctggaaa tgaaagatct
     1621 cttccagcac ccgacgatcg aagagcttac ccagtacgta gagcgtgccg aaggcaaaca
     1681 ggcagaccaa ggcccggtgg agggcgaagt catcctgacg ccgatccagc gctggttctt
     1741 tgaaaagaac ttcacgaaca agcaccactg gaaccaatct gtgatgcttc acgccaaaaa
     1801 gggctttggt cctgaacggg tggagaaaac attgcaggcg ctgatcgagc atcatgacgc
     1861 gctccgtatg gtcta
//
