LOCUS       gnlProkkaBHJHNLFJ_118   1833 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BHJHNLFJ_118.
ACCESSION   gnlProkkaBHJHNLFJ_118
VERSION     gnlProkkaBHJHNLFJ_118
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 18:47:13
            Original ID  :: gnl|Prokka|BHJHNLFJ_118
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 1833
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..1833
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[0:1833]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..1833
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..1833
                     /SMILES="NC(CC(C)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..1833
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS             1..1833
                     /NRPS_PKS="Domain: AMP-binding (24-412). E-value: 4.9e-107.
                     Score: 349.9. Matches aSDomain:
                     nrpspksdomains_ctg116_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (517-585). E-value: 3.1e-28. Score:
                     89.7. Matches aSDomain: nrpspksdomains_ctg116_1_PCP.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     352.5; E-value: 5.2e-107)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg116_1"
                     /sec_met_domain="AMP-binding (E-value: 2.7e-116, bitscore:
                     374.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 5.4e-20, bitscore:
                     58.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQALLEAWKGKALPVPTDKTVHQLFEETAQRHKDRPAVTYNGQSW
                     TYGELNAKANRLARILMDCGISPDDRVGILTKPSLEMSAAVLGVLKAGAAFVPIDPDYP
                     DQRIEYILQDSGAKLLLKQEGISVPDSFSGDVILLDGSRTILSLPLDENDEENPETAVT
                     AENLAYMIYTSGTTGQPKGVMVEHHALVNLCFWHHDAFSMTAEDRSAKYAGFGFDASIW
                     EMFPTWTIGAELHVIDEAIRLDIVRLNDYFETNGVTITFLPTQLAEQFMELENTSLRVL
                     LTGGDKLKRAVKKPYTLVNNYGPTENTVVATSAEIHPEEGSLSIGRAIANTRVYILGEG
                     NQVQPEGVAGELCVAGRGLARGYLNREDETAKRFVADPFVPGERMYRTGDLVKWTGGGI
                     EYIGRIDQQVKVRGYRIELSEIEVQLAQLSEVQDAAVTAVKDKGGNTAIAAYVTPETAD
                     IEALKSALKETLPDYMIPAFWVTLNELPVTANGKVDRKALPEPDIEAGSGEYKAPTTDM
                     EELLAGIWQDVLGMSEVGVTDNFFSLGGDSIKGIQMASRLNQHGWKLEMKDLFQHPTIE
                     ELTQYVERAEGKQADQGPVEGEVILTPIQRWFFEN"
     aSDomain        73..1236
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg116_1_AMP-binding.1"
                     /evalue="4.90E-107"
                     /label="ctg116_1_AMP-binding.1"
                     /locus_tag="ctg116_1"
                     /protein_end="412"
                     /protein_start="24"
                     /score="349.9"
                     /specificity="substrate consensus: Leu"
                     /tool="antismash"
                     /translation="FEETAQRHKDRPAVTYNGQSWTYGELNAKANRLARILMDCGISPD
                     DRVGILTKPSLEMSAAVLGVLKAGAAFVPIDPDYPDQRIEYILQDSGAKLLLKQEGISV
                     PDSFSGDVILLDGSRTILSLPLDENDEENPETAVTAENLAYMIYTSGTTGQPKGVMVEH
                     HALVNLCFWHHDAFSMTAEDRSAKYAGFGFDASIWEMFPTWTIGAELHVIDEAIRLDIV
                     RLNDYFETNGVTITFLPTQLAEQFMELENTSLRVLLTGGDKLKRAVKKPYTLVNNYGPT
                     ENTVVATSAEIHPEEGSLSIGRAIANTRVYILGEGNQVQPEGVAGELCVAGRGLARGYL
                     NREDETAKRFVADPFVPGERMYRTGDLVKWTGGGIEYIGRIDQQVKVR"
     aSModule        73..1755
                     /complete
                     /domains="nrpspksdomains_ctg116_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg116_1_PCP.1"
                     /locus_tags="ctg116_1"
                     /monomer_pairings="Leu -> Leu"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       259..300
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg116_1_0001"
                     /evalue="5.40E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg116_1"
                     /protein_end="100"
                     /protein_start="86"
                     /score="19.4"
                     /tool="antismash"
                     /translation="LGVLKAGAAFVPID"
     CDS_motif       502..561
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg116_1_0002"
                     /evalue="4.10E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg116_1"
                     /protein_end="187"
                     /protein_start="167"
                     /score="34.6"
                     /tool="antismash"
                     /translation="AYMIYTSGTTGQPKGVMVEH"
     CDS_motif       901..930
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg116_1_0003"
                     /evalue="3.20E-03"
                     /label="NRPS-A_a5"
                     /locus_tag="ctg116_1"
                     /protein_end="310"
                     /protein_start="300"
                     /score="10.1"
                     /tool="antismash"
                     /translation="NYGPTENTVV"
     CDS_motif       1033..1122
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg116_1_0004"
                     /evalue="2.30E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg116_1"
                     /protein_end="374"
                     /protein_start="344"
                     /score="51.8"
                     /tool="antismash"
                     /translation="PEGVAGELCVAGRGLARGYLNREDETAKRF"
     CDS_motif       1201..1266
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg116_1_0005"
                     /evalue="1.20E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg116_1"
                     /protein_end="422"
                     /protein_start="400"
                     /score="36.5"
                     /tool="antismash"
                     /translation="YIGRIDQQVKVRGYRIELSEIE"
     aSDomain        1552..1755
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg116_1_PCP.1"
                     /evalue="3.10E-28"
                     /label="ctg116_1_PCP.1"
                     /locus_tag="ctg116_1"
                     /protein_end="585"
                     /protein_start="517"
                     /score="89.7"
                     /tool="antismash"
                     /translation="EELLAGIWQDVLGMSEVGVTDNFFSLGGDSIKGIQMASRLNQHGW
                     KLEMKDLFQHPTIEELTQYVERA"
     CDS_motif       1801..1830
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg116_1_0006"
                     /evalue="3.80E-05"
                     /label="NRPS-E1"
                     /locus_tag="ctg116_1"
                     /protein_end="610"
                     /protein_start="600"
                     /score="16.3"
                     /tool="antismash"
                     /translation="LTPIQRWFFE"
ORIGIN
        1 aatcaagcgc ttcttgaggc atggaagggc aaagcgctgc ctgtgccgac agacaaaacg
       61 gttcatcagc tattcgaaga gactgcccag cgccacaaag accgcccggc tgtcacatac
      121 aacggccagt cttggacgta cggcgagctg aatgcgaagg caaaccgtct cgcgcggatt
      181 ctgatggact gcggcatcag cccggatgac cgcgtcggca ttctcacgaa gccgtcgctt
      241 gaaatgtccg ccgcggtgct tggcgtctta aaagcgggag cggcgtttgt gccgattgat
      301 cctgactacc cggatcagcg gattgagtat attttacagg acagcggcgc gaagcttctc
      361 ttgaagcaag aaggcatttc agtgccggat agcttctcag gagacgttat tcttctcgac
      421 ggaagccgca cgattctaag cttgccgctt gatgaaaacg atgaggaaaa tccagagacg
      481 gctgtaaccg cggagaactt ggcgtacatg atttacacgt caggaacgac cggacagccg
      541 aagggtgtca tggtcgagca ccatgcgctt gtgaacctgt gcttctggca ccacgacgcg
      601 ttcagcatga cagcggagga ccgcagtgcg aagtacgcgg gcttcgggtt cgacgcttcc
      661 atttgggaga tgttcccgac ctggacgatc ggcgccgaac ttcacgtcat tgatgaagcg
      721 atccgcctcg atatcgtccg cctgaacgat tattttgaaa cgaacggcgt aacgatcacg
      781 ttcctgccga cacagcttgc ggaacagttc atggagcttg agaacacatc actccgtgtt
      841 ctcttgacag gcggagacaa gctgaagcgc gccgtgaaaa agccgtacac actcgtcaac
      901 aactacgggc cgacagaaaa cacggtcgtt gccacaagcg cagaaatcca tccggaggaa
      961 ggttcgcttt ccatcggacg ggccattgcc aatacgagag tgtacattct cggcgagggc
     1021 aatcaggtgc agccggaagg cgtagccgga gagctttgcg tggcgggacg cggattagcg
     1081 cgaggctatc tgaatcgaga agacgaaacc gcgaagcggt ttgtcgctga tccgtttgtg
     1141 ccgggtgagc gcatgtaccg caccggcgat ttggtgaaat ggacgggcgg cggcatcgaa
     1201 tacatcggcc ggatcgacca gcaggtcaag gtccgcggct accggatcga gctttcagaa
     1261 attgaagtcc agctcgccca gctttctgag gtgcaggatg cggcggtgac agctgtcaaa
     1321 gataaaggag gcaacacagc gatcgcggcg tatgtcacac cggaaacagc tgacatagaa
     1381 gcactgaaat cagcactgaa ggaaaccctg ccggattaca tgatcccggc gttctgggtg
     1441 acgctgaacg agcttccggt tacggcaaac ggcaaagtgg accgcaaagc cttgcctgag
     1501 ccggacatcg aagcgggaag cggagaatac aaagcgccga cgaccgacat ggaagagctg
     1561 cttgccggca tctggcagga cgtgcttgga atgtctgaag tcggtgtcac cgacaatttc
     1621 ttctcgcttg gcggagattc catcaaagga attcaaatgg cgagccgctt gaaccagcac
     1681 ggctggaagc tggaaatgaa agatctcttc cagcacccga cgatcgaaga gcttacccag
     1741 tacgtagagc gtgccgaagg caaacaggca gaccaaggcc cggtggaggg cgaagtcatc
     1801 ctgacgccga tccagcgctg gttctttgaa aat
//
