LOCUS       gnlProkkaCCFHKELF_88   13636 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CCFHKELF_88.
ACCESSION   gnlProkkaCCFHKELF_88
VERSION     gnlProkkaCCFHKELF_88
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 19:05:49
            Original ID  :: gnl|Prokka|CCFHKELF_88
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13636
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13636
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[2838:3636]"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2839..3636
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..13636
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13636
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene"
                     /region_number="1"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /tool="antismash"
     CDS             2..109
                     /locus_tag="ctg86_1"
                     /transl_table=11
                     /translation="MCVLRRVSCVEHEKDTVLLSLSFILLQKNGYFKEK"
     CDS             complement(163..720)
                     /locus_tag="ctg86_2"
                     /transl_table=11
                     /translation="MKRKQLLYTEERKWEYGTILIEDGVCLIENGEGDILLADTLQHSP
                     IWVHHKGKWEQAGFQDQLVLACGEENISLSGGERIRYEKSVKRPLMALLDSLDDETFLA
                     FLQHLHSFGLSVFDCVFSYNKGVFSNTSAGQGVSFYHFSNDTAQCAMQHHYSNEGTGDR
                     FEWTASNGKRSIMYSAVQRGRK"
     CDS             890..2734
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177:asparagine synthase (glutamine-hydrolyzing)
                     (Score: 586.7; E-value: 8.6e-178)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg86_3"
                     /sec_met_domain="GATase_7 (E-value: 1.4e-48, bitscore:
                     155.4, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 2.1e-101, bitscore:
                     331.5, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGITGWVDFKKQLVQEKQTMDRMTDTLSKRGPDDSNVWGEHHVL
                     FGHKRLAVVDIEGGRQPMACTYKGDTYTIIYNGELYNTEDLRKELRARGHQFERTSDTE
                     VLLHSYIEWQEDCVDHLNGIFAFAVWDEKRNLLFAARDRLGVKPFFYTKEGSSFLFGSE
                     IKAILAHPDIKARVDRTGLSEIFGLGPSRTPGTGIFKGIKEIRPAHALTFSKDGLNIWR
                     YWNVESEKHTDSFDDTVANVRSLFQDAVTRQLVSDVPVCTFLSGGLDSSAITAIAAGHF
                     EKEGKAPLHTYSIDYEENDKFFQASAFQPNDDGPWIEKMTEAFGTTHHKCVISQKDLVD
                     HLEEAVLVKDLPGMADVDSSLLWFCREIKKDFVVSLSGECADEIFGGYPWFHTADVESG
                     FPWMRSTEERIKLLSDSWQKKLNLKEYVNAKYEETLAETPLLDGETGVDKARRQLFYLN
                     MLWFMTNLLDRKDRMSMGASLEVRVPFADHRLVEYVWNIPWEMKMHDNREKGILRKALE
                     GILPDDILYRKKSPYPKTHHPEYTKGVSEWLKTIRSQKDSVLHTLLDRKQLDQLLETEG
                     SSFKVPWFGQLMKGPQLIAHLAQIHTWFEAYRIDIDEG"
     CDS             2839..3636
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg86_4"
                     /sec_met_domain="phytoene_synt (E-value: 6.2e-31, bitscore:
                     99.1, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEIKEAYQQCGQIVSAREPACYKAFSFLPLKQRQAAWAVMAFCH
                     TAANADEKALSAIEAEAEDVFSGTYNGNHFLWKAFGHAYQTFTLDSKPFREFIAAQKAE
                     DKPFGNLDELLMHAYQTGGAAGLMLLPIMARRHQKQLTYAAGSLGLAIQLIRILRDIGT
                     GQQQKSRIPREVMQQFGYTEDDLQKGVVNKAFTMTWEYIAFEAEAYLEECQDALPLFPQ
                     YSQKTVKAALHLHRAVLEKIRAKQHDVFQHHFALTERSEADSL"
     CDS             complement(3674..4936)
                     /gene_functions="transport (smcogs) SMCOG1086:MATE efflux
                     family protein (Score: 326.6; E-value: 3.5e-99)"
                     /gene_kind="transport"
                     /locus_tag="ctg86_5"
                     /transl_table=11
                     /translation="MFMGNADTLMLSQYSDNSVAAVGVSNQILNLIIVMFSFIATGTTV
                     IISQFLGSRQKKEAMEVAYVSIGANFFISLAISAVVFFAAVPLLHMMGLSDALMPDAKV
                     FLQVVGGLSFIQALIMTFSAILKSYGYTKDTMFVTIGMNILNIAGNFVVIFGLFGFPVL
                     GVAGVAMSTSIARVIGLIAMIVIVNKRIQLKMSLKKVFHMHKEHLRKLLKIGIPSAGEQ
                     LSYNLSQMIVTYFIAIMGAQALTTKVYTQNITMFILLFGTAISQGTQILIGRYIGGKQF
                     DAAYERCMKSLYWALGIAAATSVLMTIFSKDLIGLFTQSPDIIATASLLIAMTIILEPG
                     RSFNVIIINSLRAAGDAKFPVYMAMISMWGIGLPLAYLFGIHLGFGLAGIWISFIADEW
                     VRGILMYRRWRSRIWIQKGMA"
     CDS             5165..6028
                     /gene_functions="regulatory (smcogs) SMCOG1287:AraC family
                     transcriptional regulator (Score: 62.6; E-value: 5.4e-19)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg86_6"
                     /transl_table=11
                     /translation="MPRILFTVPPFPVFIAAGEGVFKKGETHVKRVFSVFDLIYVKQGT
                     LYITENETSFSVEGGEYILLSPGLEHYGTKGSDEATSYYWLHFDEHRYEFTAKGGSNWS
                     ELQQEKGSFEEPARYGLALPRKGKVQRPQFMAQQFEKLIDYSAENSDLPLRKQILFEEL
                     MLHLQKEAFQIPSAKERVAWEAARYLQEHYKEKTTIKDLSLALHYHQDYVSRCMQQVLG
                     VTPAQYTNRVRMTEAKRLLSSTNDKMGVIAETVGMEDPTYFSKLFKQIEGISPIEYRKI
                     VSRKVQ"
     CDS             6046..7059
                     /gene_functions="regulatory (smcogs) SMCOG1078:LacI family
                     transcription regulator (Score: 365; E-value: 6.3e-111)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg86_7"
                     /transl_table=11
                     /translation="MKTTIYDVAKAAGVSITTVSRVINNTGRISDKTRQKVMNVMNEMA
                     YTPNVHAAALTGKRTNMIALVAPDISNPFYGELAKSIEERADELGFQMLICSTDYDPKK
                     ETKYFSVLKQKKVDGIIFATGIESHDSMSALEEIASEQIPIAMISQDKPLLPMDIVVID
                     DVRGGYEAAKHLLSLGHTNIACIIGDGSTTGEKNRIKGFRQAMKEAGVPIDESLIIQTR
                     FSLESGKEEAGKLLDRNAPTAIFAFNDVLACAAIQAARIRSIKVPDDLSIIGFDNTILA
                     EMAAPPLTTIAQPIKEMGRSVIELLAEAIEGKRKAKQKIVLPPELVVRHSTSPLNT"
     CDS             7269..8297
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079:oxidoreductase (Score: 210.6; E-value: 6.6e-64)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg86_8"
                     /transl_table=11
                     /translation="MEHQVRCAVLGLGRLGYYHAKNLVTSVPGAKLVSVSDLLKGRAEQ
                     VARELGIEKWSEDPYEVLEDIDIDAVIIVTPTSTHGDMIIKAAENGKQIFVEKPLTLSL
                     EESRAVSEKVKETGVICQVGFMRRFDPAYADAKRRIDAGEIGKPIYYKGFTRDQGAPPA
                     EFIKHSGGIFIDCSIHDYDIARYLLGAEITSVSGHGRILNNPFMEQYGDVDQALTYIEF
                     DSGAAGDVEASRTSPYGHDIRAEVIGTEGSIFIGTLRHQHVTILSAKGSSYDIIPDFQT
                     RFHEAYCLELQHFAECVRDRKTPIVTDIDATINLEVGIAATNSFRSGRPVQLDVKRAYT
                     GM"
     CDS             complement(8349..8858)
                     /gene_functions="other (smcogs) SMCOG1250:DinB (Score:
                     156.2; E-value: 1.2e-47)"
                     /gene_kind="other"
                     /locus_tag="ctg86_9"
                     /transl_table=11
                     /translation="MTDAKQFYDYHSWANKKIFTHIENLPEETAYQEVKSVFPSVSDVL
                     LHMCRADYIWLNVLSGVAYQEIIDSAGKLESAQGNMAAIKQHAAELESQYHDFFSRQTD
                     LEQTFTMQHPKLGTLESTYADTILHVVNHGTYHRGNVTAMLRQLGHSGAPTDYMYYLYE
                     KRESKG"
     CDS             complement(8908..9519)
                     /locus_tag="ctg86_10"
                     /transl_table=11
                     /translation="MNAIIHGIVLAFGLILPLGVQNVFIFQQGAWQKHIWRALPAVISA
                     SVCDTLLIVLAVAGVSVIVQELPVFETVMMAGGFLFLLYMGWVTWNSRPNTSQNEKHTF
                     TPKKQVAFAAAVSLLNPHAILDTIGVIGTSSLQYSGLEKWLFMAACIAVSWIWFISLAI
                     AGRLFQTIDTSGRLMLIVNKCSAAVMWAAAGYFGVSLFCN"
     CDS             9778..11091
                     /NRPS_PKS="Domain: Aminotran_1_2 (74-415). E-value:
                     1.3e-34. Score: 111.7. Matches aSDomain:
                     nrpspksdomains_ctg86_11_Aminotran_1_2.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 308; E-value: 1.6e-93)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg86_11"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1e-34, bitscore:
                     111.7, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQVNRSTVTAAIDELTSQGLLEGRRGGGTKVVNSTWSVLAAEPP
                     LDWSDYVRSGIHRANSSIIQAINQNEPRADIIRLGTGELSPDLVPADTIGRMFQQINPG
                     VLSLGYEQPKGNRQLREAVADHLKGKKIHVSPSAILIVSGALQALQLISIGLLKRDSVI
                     LTEKPSYLQSLHVFQSAGMRLRGLPMDDEGVKAGLVSSNRKQYGGQLLYTIPSFHNPTG
                     TVMSEQRRKEIISLSKIEQLPIIEDDAYGDLWFEEKPPQPLKAMDHEGNILYLGTFSKT
                     VSPGLRIGWLAGPEPVIERLADIKMQTDYGSSGLSQWAAAEWLSQGYYEEHLTWVRRKL
                     KERRDAAVHFLERYAGDIATWRIPAGGFYIWVTFHKNLPVSRFFYGLLKRQVLVNPGYI
                     YDGEDRNSIRLSYSYASLGDLETGIKAAAETARRLMMS"
     aSDomain        10000..11022
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg86_11_Aminotran_1_2.1"
                     /evalue="1.30E-34"
                     /label="ctg86_11_Aminotran_1_2.1"
                     /locus_tag="ctg86_11"
                     /protein_end="415"
                     /protein_start="74"
                     /score="111.7"
                     /tool="antismash"
                     /translation="DIIRLGTGELSPDLVPADTIGRMFQQINPGVLSLGYEQPKGNRQL
                     REAVADHLKGKKIHVSPSAILIVSGALQALQLISIGLLKRDSVILTEKPSYLQSLHVFQ
                     SAGMRLRGLPMDDEGVKAGLVSSNRKQYGGQLLYTIPSFHNPTGTVMSEQRRKEIISLS
                     KIEQLPIIEDDAYGDLWFEEKPPQPLKAMDHEGNILYLGTFSKTVSPGLRIGWLAGPEP
                     VIERLADIKMQTDYGSSGLSQWAAAEWLSQGYYEEHLTWVRRKLKERRDAAVHFLERYA
                     GDIATWRIPAGGFYIWVTFHKNLPVSRFFYGLLKRQVLVNPGYIYDGEDRNSIRLSYSY
                     A"
     CDS             complement(11099..11737)
                     /gene_functions="other (smcogs) SMCOG1286:Pentapeptide
                     repeat protein (Score: 35.4; E-value: 7.8e-11)"
                     /gene_kind="other"
                     /locus_tag="ctg86_12"
                     /transl_table=11
                     /translation="MNKIAIQKPNIPENLQTADFHDAVTQDDVISMHLFEDCTICGEDI
                     ERLCVEKTVFRNVVFIDVSFRHIELTDVIFEKCDLSNADFSGAVIHRTSVKQSKMVGMN
                     VAEATLRNVSFEECHGHFSSFSYSNMKQVRFDHCALMQSECSNTVLQQTHFDGCELEGA
                     SFTGTSLQNMDISTCRFEQLHVSLDKLKGCKIAPEHAIAFARALGAVIV"
     CDS             11943..12749
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036:alpha/beta hydrolase fold protein (Score: 125.9;
                     E-value: 4.1e-38)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg86_13"
                     /sec_met_domain="PF00561 (E-value: 8.7e-25, bitscore: 79.3,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.2e-19, bitscore:
                     62.4, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGHYVKTEEHVTLFVEDIGHGRPIIFLHGWPLNHKMFEYQMNELP
                     KRGFRFIGVDLRGYGQSDRPWEGYDYDTMADDVKAVIYTLQLENAILAGFSMGCAIAIR
                     YMARHEGADVDKLILLSAAAPAFTKRPGYPYGMRKQDIDDMIELFKADRPKTLADLGEQ
                     FFEKKVSPELRQWFLNLMLEASSYGTIHSGIALRDEDLRKELAAIKVPTLILHGRKDRI
                     APFDFAKELKRGIKQSELVPFANSGHGAFYEEKEKINSLIAQFSNS"
     CDS             complement(12744..13190)
                     /locus_tag="ctg86_14"
                     /transl_table=11
                     /translation="MDVVDELIELHEEHVSGLLRLCRQAGWPDYGEQELALLVQQGRFF
                     GYQNVSGDIISCIGLFLFGRLASIGLVIVDKEYQRLGLGRRMVNACITQTDENTAIRLC
                     ATKEGLPLYEKAGFHTAGSVRKYSCHSFQPYTKKLDSQMSGFFL"
ORIGIN
        1 cggctgtgtt ttgagaagag tttcttgtgt ggaacatgag aaagacaccg tccttttaag
       61 tctttctttt attttattac agaagaatgg atattttaag gaaaaataaa ggctgtcgag
      121 attttctcga cagcctgaag cggtgctcga tgcaccgctt ttttatttgc gcccccgttg
      181 gactgctgaa tacataatgg atcgctttcc gtttgaagcc gtccattcaa aacggtctcc
      241 tgtcccttcg ttgctgtagt gatgctgcat cgcgcattgt gcggtgtcat ttgaaaagtg
      301 ataaaaggac acaccctgcc ccgccgaagt attcgaaaag actcctttat tataagaaaa
      361 gacgcaatcg aataccgata agccgaagct gtgcaagtgc tgcagaaatg cgagaaaggt
      421 ttcgtcgtca agcgaatcca aaagcgccat gagcggccgc ttgactgatt tctcatagcg
      481 gatgcgttct cccccggaaa gggagatgtt ttcttcaccg catgccagaa ccaattgatc
      541 ctggaagccg gcttgctccc actttccttt atgatggacc cagattgggc tgtgttggag
      601 agtgtccgcc aaaagtatat caccttctcc gttttcgatt aaacagacgc cgtcttcgat
      661 gaggatggtg ccgtattccc attttcgttc ctctgtatat aacaattgtt tccgtttcat
      721 ccatgctgtc tcctttttct tcattcctct cttttctttc caattcaagc ctgtcccata
      781 caactctttt atggacaaat caactatctg cctatagatg cataaactta ctaaggtgct
      841 gaaagaaacg aaattgttac gaaagaaacg ggattggagc tgatgtcaca tgtgtggaat
      901 tacgggttgg gtcgatttta aaaagcagct cgtccaggaa aaacaaacga tggacagaat
      961 gacagacact ctttccaaac gagggcctga tgattcaaac gtttgggggg agcaccatgt
     1021 tttattcgga cataaaagac ttgcggttgt tgatattgaa ggaggacgcc agccgatggc
     1081 gtgtacctat aaaggggata cgtacaccat tatttacaat ggcgagctgt ataacacgga
     1141 agatttgcgc aaagaattgc gggcgcgggg ccatcaattc gagcgtacgt cagataccga
     1201 ggtgcttctg cacagctaca tcgagtggca ggaagactgt gtcgaccatc tcaatggcat
     1261 attcgctttc gctgtgtggg atgaaaagcg taatctgctg tttgccgcga gagaccgtct
     1321 cggtgtaaag ccattttttt acacgaagga aggctcttca tttctcttcg ggtcggaaat
     1381 caaagcaatc ctcgcgcacc ctgatataaa agcgcgagtg gacagaacgg gactttctga
     1441 aattttcggt cttggaccgt ccagaacccc gggcactggc atatttaaag gtataaaaga
     1501 aatccgcccg gctcatgcgc tgacattttc caaagacgga cttaatattt ggcgttattg
     1561 gaatgttgaa agcgaaaaac atacggacag ttttgatgac acggttgcca atgtcagatc
     1621 gttatttcag gacgcggtga cgcggcagct tgtgtcggat gtgcctgttt gcacattcct
     1681 atcaggcggt ctggactcaa gcgcgattac agcgattgcg gcgggccatt ttgaaaagga
     1741 aggaaaagca ccgcttcata cttattcgat tgattacgaa gagaacgata aattttttca
     1801 agcaagcgct tttcagccga atgatgacgg accatggatt gaaaaaatga cagaggcttt
     1861 cggcacaacg caccacaaat gcgtcatcag ccaaaaagat ctcgttgatc atttggagga
     1921 agctgtactg gtcaaagact tgccgggaat ggcggatgtc gactcatccc tgctgtggtt
     1981 ttgccgggaa atcaaaaagg actttgtcgt cagcctatcg ggagagtgcg cggatgagat
     2041 tttcggcggg tacccgtggt tccatacggc agatgttgag tctggctttc catggatgag
     2101 atcaacggag gagcggatca agctgctttc tgactcatgg cagaaaaaat tgaatctgaa
     2161 agaatacgta aatgccaaat atgaagaaac cttggcagaa acgccattat tagatggtga
     2221 aacgggtgtg gataaagcaa gaagacagct gttctattta aatatgcttt ggtttatgac
     2281 gaaccttttg gatcggaagg atcgcatgag catgggggcg agcctggaag tgcgggtgcc
     2341 gttcgccgat caccggcttg tggaatatgt ttggaatatt ccgtgggaaa tgaaaatgca
     2401 tgataatcgg gaaaaaggca ttttacgcaa agcgcttgaa ggtattttgc ctgatgacat
     2461 tctgtatcgc aaaaaaagcc cgtatccgaa aacacatcat ccggaatata caaaaggcgt
     2521 cagcgaatgg ctgaaaacga tcagaagcca aaaggactcc gtgctccata ccttgctgga
     2581 cagaaaacaa ttagatcagc ttttagaaac ggaaggctcc tccttcaagg tgccgtggtt
     2641 cggacagctc atgaagggac ctcagctgat cgcccatctt gctcaaattc atacatggtt
     2701 tgaagcgtat cgcattgata ttgatgaagg ataaagaaaa agccgattct gctcaaagga
     2761 atcggctttt tcttcatata caattgcgag aaaacataat agacttgaag aagcagtgat
     2821 acataggagt gaacagaaat gaaagagata aaagaagcct atcagcaatg cggccagatc
     2881 gtcagcgccc gcgaaccagc ctgttacaaa gcattttcgt ttcttccgct gaagcaaagg
     2941 caggcagctt gggcggttat ggcgttttgc catacggcag ccaatgcgga tgagaaggcg
     3001 ttatctgcca ttgaagcgga ggcggaagat gttttttccg gtacgtataa cgggaatcat
     3061 tttttgtgga aggctttcgg ccatgcgtac caaaccttta cactggacag caagccattc
     3121 cgtgagttca ttgccgcaca gaaagcggaa gataaaccgt ttggaaacct tgatgaattg
     3181 ctcatgcacg cataccagac aggcggcgca gccggattga tgctgctccc gattatggcg
     3241 cgccggcatc agaaacagct gacatatgca gccggttctc tcggtttagc gattcagctg
     3301 attcggattc tgagagatat cggcactggc caacagcaaa aaagccgtat ccctcgggaa
     3361 gtgatgcagc aatttggata tacagaggac gaccttcaaa aaggcgtcgt gaataaggcg
     3421 ttcacaatga cgtgggagta tatcgctttt gaagcagaag cctaccttga agagtgtcag
     3481 gatgccttgc cgctatttcc gcagtattct caaaaaacgg tgaaagccgc tcttcatttg
     3541 caccgggctg ttttagaaaa aatccgggcg aagcagcacg atgtatttca acatcacttc
     3601 gctctcacag agagaagtga agcagattct ctctgatatc taaaaaaaca cccggtcttg
     3661 attgagccgg gtgttatgcc ataccttttt gaatccaaat acgtgagcgc catcttctgt
     3721 acattaagat tccccggacc cattcatccg cgataaaaga aatccaaatg ccggcaagac
     3781 cgaaaccgag atggatgccg aaaagataag caagcgggag gccgatgccc cacattgaaa
     3841 tcattgccat gtaaaccggg aatttcgcat cccccgcagc ccgcagagag ttaatgataa
     3901 tgacattaaa cgagcggcct ggttcaagaa taatggtcat ggcaatcaat aggcttgcag
     3961 ttgctataat gtcagggctt tgtgtgaaga gtccgatcag gtcttttgaa aagatcgtca
     4021 tcaaaacaga ggtagccgca gcaattccga gtgcccaata taagctcttc atgcagcgct
     4081 cataagcggc atcaaattgt ttgccgccga tataacggcc gattaagatt tgtgtaccct
     4141 ggctgatcgc agtgccgaac agcaaaataa acatcgtaat attttgcgta tacacttttg
     4201 ttgtcaacgc ctgcgcgccc atgatggcga taaaatacgt aacaatcatt tgcgaaaggt
     4261 tgtatgaaag ctgctctccc gcagaaggaa tgccgatttt cagcagcttg cgcaaatgct
     4321 ctttatgcat atgaaagact tttttcagcg acatcttcag ctggatgcgt ttgttgacaa
     4381 tcacaatcat cgcgattaat ccgatgacgc gggcgataga tgtggacatg gccacaccgg
     4441 caacaccgag aacaggaaag ccgaacaaac cgaaaatcac aacaaagttt ccggcaatgt
     4501 ttaaaatgtt catgccgata gtgacaaaca ttgtatcttt tgtgtagccg tagcttttta
     4561 agatcgcgct gaatgtcatg attaaagcct gaataaagga cagacctccg acaacttgta
     4621 aaaagacttt cgcatcaggc atcagtgcgt ctgataatcc catcatatga agcagaggga
     4681 cagccgcgaa aaagacgacg gcgctgatgg ccaggctgat gaagaagttg gcgccgattg
     4741 acacataagc gacttccatg gcttctttct tttgccgtga gcctagaaat tgtgaaatga
     4801 taacggtcgt tcctgttgcg ataaagctga acatcacgat aattaaattt aaaatctggt
     4861 tgctgacgcc gactgctgcc acgctgttat ccgagtattg gctgagcatc agtgtatcgg
     4921 cattacccat aaacatatat aatgagacct caataaagat cggccaagta agcgaaaata
     4981 atgagaacgt tttgtcagcg gtttttttca aagcagttga tttgaagaca gcttgtttca
     5041 tagtgtctaa cccctttcgt aaataaaatc aacgttttaa agtgtacctc catttcctta
     5101 taataaaaag ggatagaaac gatacttctt gtaaaaatcc gacttaaaaa ggaggatgat
     5161 tcaaatgcct cgcatcctgt ttacagtccc gccttttccg gtatttatcg cagctgggga
     5221 aggggttttt aaaaaaggag aaacccatgt gaaacgtgta ttctccgtgt ttgatctgat
     5281 atatgtcaaa cagggaacgt tatatataac ggaaaatgaa acatcgtttt ctgttgaagg
     5341 cggcgagtac atcttgcttt ctcccggtct tgaacactac gggacgaagg gcagtgatga
     5401 agcaacctcc tactattggc ttcacttcga tgaacatcga tatgaattta cggcaaaggg
     5461 aggcagcaac tggtctgagc ttcagcagga aaaagggagc ttcgaagagc cggcccgcta
     5521 cggattggct ttgccgagaa aaggcaaggt gcagcgcccg cagtttatgg cgcagcagtt
     5581 tgaaaagctg atcgattact ccgcggaaaa ctctgatttg ccgctcagaa agcaaatttt
     5641 atttgaggag ctgatgctgc atcttcaaaa agaagcgttc caaataccgt ctgcgaaaga
     5701 gcgggtagcc tgggaggcgg cccggtactt acaggagcac tataaggaaa agacgacaat
     5761 caaggatctg tcgctcgccc ttcactatca tcaggattat gtgagccgct gcatgcagca
     5821 ggtgctcggc gtaactccgg cacaatacac gaaccgggtg agaatgacgg aagcgaagcg
     5881 tcttttatcc tctacaaatg ataaaatggg cgttattgcg gaaacggtcg gaatggaaga
     5941 tccgacatac ttttcaaaac tctttaagca gatagaaggc atttcaccaa ttgaataccg
     6001 gaaaattgtc agccggaaag ttcaataacc agacgaggga tgaacatgaa aacaacaatt
     6061 tacgatgtgg caaaggcggc gggtgtctcg atcacaactg tgtcccgtgt gataaacaat
     6121 acggggagaa tcagcgataa aacacggcag aaggtcatga atgtcatgaa tgaaatggca
     6181 tacacgccca atgtccacgc cgcggcgtta acgggaaaac gaacgaatat gattgctctc
     6241 gtggcgcctg atatttcaaa tccgttttac ggcgaactgg ccaaaagcat tgaggaaaga
     6301 gcggatgagc tcggttttca aatgttgatt tgcagcaccg attacgatcc aaaaaaagaa
     6361 acaaagtatt tttctgtgct gaaacagaaa aaggtggatg gcattatttt tgcaacaggg
     6421 attgaaagcc atgacagtat gtctgctttg gaggaaatcg ccagtgaaca aattccgatt
     6481 gccatgattt ctcaggataa gccgcttctt ccgatggata ttgttgtgat agatgacgtt
     6541 cgtggcggat atgaggctgc caagcatctt ctgtcactcg gccacacgaa catcgcctgc
     6601 attatcggag acgggtcaac gacaggcgaa aaaaatagaa tcaaaggctt ccgtcaggcg
     6661 atgaaggaag cgggcgtgcc cattgatgaa tcacttatca tccagacgcg gttttccttg
     6721 gaaagcggca aggaagaagc gggaaaattg ctcgacagaa acgctccgac tgctattttt
     6781 gccttcaacg acgtattggc ttgtgccgcc atacaagctg cgagaataag aagcataaaa
     6841 gtgccggatg atctttctat cattggtttt gataatacga tactcgcaga aatggcggct
     6901 ccgcccctga caaccatagc ccagccgata aaagagatgg ggcggagcgt catcgaactg
     6961 ctggcagaag caatagaggg aaaacgaaag gcgaaacaaa aaatagtgct cccgcctgag
     7021 cttgtagtca gacattctac atcaccgctc aacacatgag cccgctaatg agcgggtttt
     7081 ttcattatga cagttgaagc aaaaaaaaac atattgcgtg taaaccaatg gcagtgtaaa
     7141 atgaaaccat cttttgagaa agcgcttgcg caaaatggca gagcggatag aaccgctgtt
     7201 tttttagttg ttaagagaaa gcgctttctc aaagcgagcc tgaaatgaga taaaggagag
     7261 gatgggacgt ggaacatcaa gtaagatgtg cagtattggg attaggaagg ctgggttatt
     7321 atcatgcgaa aaatctcgtc accagtgtgc cgggggcaaa gctggttagt gtcagtgacc
     7381 tgttaaaagg gagagcggag caggttgcca gagaactcgg tatcgaaaaa tggtcagagg
     7441 acccgtatga agtgttagaa gatattgaca ttgatgctgt cattatcgta acgccgacaa
     7501 gcacacatgg tgatatgatc atcaaagctg ccgagaacgg caaacagatc tttgttgaaa
     7561 aaccgctgac attaagcctt gaggaatcaa gagcagtttc tgaaaaagtg aaagagacag
     7621 gtgtcatctg ccaagtcggc tttatgagac ggttcgatcc agcatacgca gatgccaaac
     7681 ggcggatcga cgctggagaa atcggcaaac ctatctatta taaaggcttt acgcgcgacc
     7741 aaggcgcgcc tcccgcagaa tttatcaaac acagcggtgg aatttttatc gactgttcca
     7801 tccatgacta tgatattgcc cgttatttgc taggggcgga aattacttct gtttcaggac
     7861 acggcaggat tctgaacaat ccgtttatgg agcagtacgg cgatgtggat caggcgctga
     7921 cgtatattga atttgactcc ggcgcagcgg gggacgtcga ggcaagcaga acctctccat
     7981 acggacatga catccgggcg gaggtgatcg ggacagaggg cagtattttc attgggacat
     8041 tgagacatca acatgtgacc atcctttcgg ctaaagggag cagttatgat atcattccag
     8101 actttcaaac tcgttttcat gaagcctact gcttggagct tcagcatttt gccgagtgtg
     8161 tccgggatcg aaaaacaccg attgtgacag atattgatgc gacgatcaat ttagaagtgg
     8221 gtatcgccgc aaccaattcc tttcgaagcg gcaggccggt acagctagat gtgaagcgcg
     8281 cttatacagg tatgtaaaag ctaatatgtt gcattttagg ctttccgcaa aaaaaagcaa
     8341 ggacattttt agcccttgct ttctcttttc tcatataaat agtacatata atcagtaggt
     8401 gcgccagaat ggcccagctg tctcagcatg gcggttacgt ttcctctgtg gtaagtgccg
     8461 tgattgacga catgcaggat ggtgtctgca taggttgatt ccagtgtacc tagtttcgga
     8521 tgctgcattg tgaaggtctg ttctaagtcc gtctggcggc tgaagaaatc atgatactgt
     8581 gactccagct cggcagcgtg ctgtttaatc gctgccatat taccttgcgc ggactctaat
     8641 ttgcctgcgc tgtctataat ctcttggtag gccactcccg aaagaacatt cagccaaatg
     8701 tagtcagccc tgcacatatg aagcagcacg tcgctgacag aaggaaatac gctctttact
     8761 tcttgatagg cagtttcctc cggcaggttt tcgatatggg taaatatttt cttgtttgcc
     8821 caagaatgat agtcataaaa ctgttttgca tcagtcataa gcatgccccc ttttctaaga
     8881 aattcgtttt tttcatctgt ttctccttca attgcaaaag agtgacaccc caaaatatcc
     8941 tgccgctgcc cacattaccg ctgcagagca tttgtttacg atcagcataa gcctgccgct
     9001 cgtatctatc gtctgaaaca accggcccgc tattgcaagg ctgataaacc aaatccaaga
     9061 cacagcgatg caggcggcca taaagagcca tttctcaagc cccgaatatt gaagagagct
     9121 cgtgccgatg acgccgatcg tgtccagaat ggcatgcggg tttaaaagag aaacagcggc
     9181 cgcaaatgca acttgctttt ttggtgtgaa cgtatgtttc tcattttggc ttgtgttcgg
     9241 acggctgttc caagtcaccc agcccatata gagcaaaaat aaaaatccgc cggccatcat
     9301 gactgtctca aacacaggca gctcctgcac aatgacagac acgcccgcaa cggctaatac
     9361 gattaacagg gtatcgcaga ctgaagcact gatgacagct gggagagccc gccaaatatg
     9421 cttttgccac gcgccttgct gaaaaataaa cacattctgc actcccagcg gcaaaattaa
     9481 gccaaacgcg agcacaattc cgtgaatgat tgcattcatg ctgaaaaagc tcccttcaca
     9541 tttttttcaa tcataagaga gattgtcact aaagtctcca gccatttggt tgggttagga
     9601 accagccaaa tgtataatgt gtaaaaaagg gggggcatga ccttgtcgca atggcagcca
     9661 agccgaaagt cggatgttcc gctgcatcgg cagatcgaac aatatatgaa agacaagatt
     9721 cttcacggag agtgggctgt agggacgaaa atcccctcac agagaacgct ggccgacatg
     9781 tttcaagtca accgcagcac agtcacagca gccatagatg aactcacgtc tcaaggcttg
     9841 ttagagggaa gaagaggcgg cggtacgaag gttgtaaaca gtacttggag cgtgctggcg
     9901 gctgagcctc cgcttgattg gagcgattac gtccgttcgg gcattcatcg cgccaattct
     9961 tccatcattc aagctattaa tcagaacgaa ccaagagcgg atatcatcag attaggaact
    10021 ggagaacttt caccggatct tgtgcctgct gacacaattg gacggatgtt tcagcaaatc
    10081 aatccgggcg tcctgtcttt aggatatgag cagccgaaag gaaaccgtca gctgcgggag
    10141 gcagtggccg accatttaaa aggaaagaag atccatgtgt caccgtctgc aattttaatt
    10201 gtgtccggtg cacttcaggc acttcagctc atctcaattg gacttttaaa acgagattct
    10261 gtcattttga cggagaagcc gtcctacctt caatccttgc atgtatttca atcagctggg
    10321 atgcggcttc gcggcttgcc gatggatgat gaaggggtca aagcggggct tgtttcttct
    10381 aatcgaaaac aatatggagg acagctgctt tacacgattc cgtcgtttca taatccgaca
    10441 ggcacagtca tgtcagagca gcgaaggaaa gagatcatca gcctgtcaaa aatagagcag
    10501 ctgcccatca ttgaggatga tgcgtacggt gatttatggt ttgaagaaaa accgccgcag
    10561 ccgttgaaag caatggatca tgagggcaat attctgtatc tgggcacgtt ttcaaaaacg
    10621 gttagccccg gcctgcgaat cggctggctt gccggtccgg agccggttat tgaaaggttg
    10681 gcggacatta aaatgcagac agactacgga tcaagcggcc tgtcccagtg ggcggctgcc
    10741 gagtggctgt cacaggggta ttatgaagag catctgactt gggtacgcag gaagcttaaa
    10801 gaaaggagag acgccgccgt tcattttctc gagcggtatg ccggggacat tgccacgtgg
    10861 cggattcccg caggcggctt ttatatttgg gtgacatttc acaaaaacct gcctgttagc
    10921 cgtttctttt atggattgct gaaacggcag gtgcttgtga atcccggcta tatttatgac
    10981 ggtgaagacc gaaacagcat caggctgtca tattcctatg catctcttgg agatttggaa
    11041 actggcatta aagcggcagc tgaaacagca cgccgcctga tgatgtccta ggctttggtt
    11101 atacgatgac agctcccagt gccctggcga aggcaatcgc atgctcaggt gcgattttgc
    11161 agcctttcaa tttgtcgagg gagacatgaa gctgttcaaa acggcacgtg ctgatgtcca
    11221 tgttttgaag ggatgtgccg gtaaagctgg cgccttccaa ttcgcatccg tcaaagtgtg
    11281 tctgctggag caccgtattg ctgcattcac tttgcataag agcacaatga tcaaatcgaa
    11341 cttgtttcat atttgaatac gaaaatgagc tgaaatgtcc gtggcattcc tcgaatgaaa
    11401 cattccgaag cgttgcttcc gccacattca ttccaaccat ttttgactgc ttaactgaag
    11461 ttctgtgaat gacagccccg ctgaaatcgg cgtttgataa atcgcacttt tcaaagatca
    11521 catcggtcag ttcaatatgc cgaaaagaca catcgataaa gacgacattt ctgaataccg
    11581 ttttttcaac acagagtctt tcgatatctt cgccgcagat ggtacaatct tcaaacaaat
    11641 gcatgctgat tacatcatcc tgcgtcacgg catcatgaaa atctgcggtt tgcaggtttt
    11701 ccggtatgtt cggtttttga attgcgattt tattcatgtg atgacatcct ttgctgtccg
    11761 aaaaacagag gcttccgggt tcaatttaat agatcgttaa ggaaattgat acatatagta
    11821 aatcgtgaag agccttttct tggtacagca gcccgcttgt tttgtaagca taaatggaaa
    11881 gcttcctata cgtcaaggcg tttacagggc gaaaaagcca aagggaacag gaggaatgcg
    11941 gaatggggca ttacgtcaaa accgaggagc atgtgacact gtttgtagag gatatcggac
    12001 atggaaggcc gatcatcttt ttgcacgggt ggccgttgaa tcataagatg tttgaatatc
    12061 aaatgaatga gcttccgaaa aggggatttc gttttatcgg cgttgatttg cggggatatg
    12121 ggcaatctga ccgcccttgg gaaggctacg attatgacac gatggccgat gatgtgaaag
    12181 cagtcattta tacgctgcag cttgagaatg cgattcttgc cggtttttca atgggctgcg
    12241 ccattgcaat ccgttatatg gcaaggcatg aaggagccga tgttgataag ctgattttac
    12301 tgtctgcggc agcccccgcg tttacaaaac gcccgggtta tccgtacggg atgaggaagc
    12361 aggatattga cgatatgatt gaattgttca aagctgatcg gcccaaaaca ctggctgatt
    12421 taggggaaca gttttttgag aaaaaagtgt ctccagagct taggcagtgg tttctcaatc
    12481 tgatgctgga ggcttcctcc tacgggacga tccactcggg catcgcatta agagatgaag
    12541 atctcagaaa ggaacttgct gcaatcaagg tgccgacgct gatcctgcac gggagaaagg
    12601 atagaattgc gccgtttgat tttgcgaaag aattgaagcg cggcatcaaa cagtcggaat
    12661 tggttccgtt tgcaaacagc gggcacggag cattttatga ggaaaaagag aagattaaca
    12721 gtttgattgc gcagttctcc aactcataag aaaaaacccg acatttgaga atcaagcttt
    12781 tttgtataag gttgaaaact gtgacagctg tactttcgca ctgaaccagc cgtatgaaaa
    12841 cctgcttttt cataaagcgg caaaccttct tttgtggcgc aaagcctgat ggcggtgttt
    12901 tcatccgttt gggtgataca ggcgtttacc atacgccggc cgagaccgag ccgttgatat
    12961 tccttgtcaa cgataacgag gccgatagaa gcaagacggc caaacaaaaa caagccgatg
    13021 caggaaataa tatcaccgct gacattttga tagccgaaaa agcgtccttg ctggacaagc
    13081 agtgccagct cttgttcgcc gtaatccggc cacccggctt gcctgcaaag ccgcaataag
    13141 ccggaaacat gttcttcatg aagctcaatc agctcatcca ctacatccat aagatcacct
    13201 gcttgttcct agtgttttgt acatgacaat atgagtgcct atgccgggaa tctcaaacgg
    13261 ttcgccgagt tcttcccacc caagttttga atagtagcct ttcacatggc ttctggcatt
    13321 gcaccagacc gcctgaacgc cgttctccgc cagtttctct tccgagtgtt tgatcagcgt
    13381 gctcccgcct ttttgatcgc gatatcctac aagcgttgcc atgcctctca gccgatatgc
    13441 tggggattct gttattaatg gctgaatttg cggggaaaaa gaggcgatgc tgatcagctt
    13501 tccttcaaaa aacgcgccga gatgaaagga gccttttgca tgatcctctt catatttgca
    13561 ttgttcaatg gattgatggg gacgcagaat gcggtgccgg atttcatacg tatcttccgc
    13621 ggaaatggtt ttgact
//
