LOCUS       gnlProkkaOIDMAAEK_55   15280 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OIDMAAEK_55.
ACCESSION   gnlProkkaOIDMAAEK_55
VERSION     gnlProkkaOIDMAAEK_55
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 19:31:58
            Original ID  :: gnl|Prokka|OIDMAAEK_55
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15280
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15280
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2091:5280]"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2092..5280
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     cand_cluster    1..15280
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15280
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     CDS             complement(2..100)
                     /locus_tag="ctg52_1"
                     /transl_table=11
                     /translation="MVGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG"
     CDS             complement(188..1630)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 158.6; E-value: 4e-48)"
                     /gene_kind="transport"
                     /locus_tag="ctg52_2"
                     /transl_table=11
                     /translation="MMMPSPAAKYYLRYIVKSRTIVSLIIFFSLITQVVFLAVPFLIKY
                     LVDHSLISKSTNSFLFLGIVVIIAVFILGLVMFIRNYFTIKLQAIISKSISNDFVEHLL
                     KLPLNFYENRTTGDIAMRVSNISMIREIMAKNGATVVLDIITLISFFIAMLTQSFKLAF
                     FAIGLAIIQFLLMMILIPRIKNLIHNDLSIQTTTQSFLVEALRAITFIKSNGLDHSILT
                     KWSNYYDKQIEAFSQRYHLDAIMDSISISIRYCAPLLLLWFGSKEVITGNLTLGGLLGF
                     SSLGTSFLLPIASLITSMQQFQLVGDTFERMQDVMETEPEQINQTSIIETELSKQDIKL
                     ENVTFTHHSLHILKEVSLNIKSGTKLALVGRTGSGKTTLSRIILGLYKPTKGKVFYGEQ
                     DLKNLNLYELRKQMGVVLQESFLFNDTIANNIAGFKSLSQDKIEQAAKRVQLHEDIIRM
                     PMDITQLSGKMAVCYQEGSVSA"
     CDS             complement(1627..2040)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg52_3"
                     /sec_met_domain="Peptidase_C39 (E-value: 4.5e-46, bitscore:
                     146.3, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRRVPLVRQMGQYECGPACLTMILSYYGSTISLNKISEQCDAQR
                     NGVSVSILKSVSEYYGLNCKVYQVSFKDLKKYINSYLPCIIFWDERHFVVLEQIKKGLF
                     HIIDPNRGKLKLSEEEFKRHYSKVILTFKKSDK"
     CDS             complement(2092..5280)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     1027.4; E-value: 0.0)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg52_4"
                     /sec_met_domain="DUF4135 (E-value: 1.8e-114, bitscore:
                     373.1, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.1e-89, bitscore:
                     290.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHTKFKRNSVWNRSSSISERKVRRSLNTNWDELTNRRFERWKSLV
                     ESDEGIRIEDVLATQNIDEETLKHTINAKEVEFINEGDHQGWLEIIQLVDEQSYKNVNI
                     EVRKDILFFSFIKPFLKIARGKLEEVLYSHSTKSLIKEELSPSVIDDLLNNLGETLSAI
                     SSRILILELNVARVSGKLRGETSEERASYFNQALLNDPAYVRSIREEYIVLTRLLATKT
                     MYWIQNTSDLLVRFHQDKGILESEFSNGQKLGKIISIDTGSGVSDTHNKGKTVAILNFE
                     TGIKIVYKPRSLEIDVKFNKFVNYLNGKNLSFDLKTVHTLNKKSYGWTQFISYKECQEE
                     LQIGKFYWRIGSYLAILYAMNAVDFHMQNLIADGEYPILVDLESLFHNNSTYTDTSAFS
                     RAQEHIERSVLRIGLLPRKINSKAGFEGIDLSALGAQEGQVSPHKTSTIVDRDKDTVRI
                     EEKNFPIPVSQHRPMLHGQIINTVAYEGNIIKGFEETYFLFMKYKQDMLEQIDSFKGVT
                     VRQILRGTSRYANLLKISLHPDFMRDGLDREMILDKLWLDTKLNPRLNQVVNSEKEGLF
                     LGDIPYFTSKPESTNMWDSSGRKINNFFKTSALNETKEKINEMNESDCHEQVSFIKTAI
                     LVIKDSYRKHKVFDINPRLHVFNPKDFFQEAIKIGDFLASRAIEGEQLDGQEDVSWIGS
                     FVDNQREDQFKISAANSSLYEGVGGISLFLAYLGRLSNNEKYTNLSKKALVAVHKNMSA
                     SSDLGAFGGIASYLYLLDHLSKLWNDEQLLKNELYSALNKLDSLIERDENNDILTGVAG
                     TAVILINLFKRYKEEQILNLITKCGNRLIQNINVMEKGVGWKVPANPTPASGFAHGASG
                     IIWALYEIYAITEQTVFKEVAEKALEFERTLFIPEKNNWADIKLENGQFRNDNFVAWCN
                     GAAGIGLSRILILPHNQNELIKDEAHVAINTTLKYGFEHDHSLCHGDLGNLDILMYAAE
                     NFNKKLSVNVTELSHKILNDIKLRGWLTGFEKNNESPSLMMGYAGIGLGLLKIFAPTEV
                     PSVLRLQSPLELKL"
     CDS             5492..6076
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Flavoprotein"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg52_5"
                     /sec_met_domain="Flavoprotein (E-value: 2.5e-29, bitscore:
                     92.2, seeds: 143, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSISILKDKKLLIGICGSISSVGISSYLLYFKSFFKEIRVVMTKT
                     AEDLIPAHTVSYFCDHVYSEHGENGKRHSHVEIGRWADIYCIIPATANILGQTANGVAM
                     NLVATTVLAHPYNTIFFPNMNDLMWNKTVVSRNIEQLRKDGHIVIEPVEIMAFEIATGT
                     RKPNRGLITPDKALLAIEKGFKERTKHPSLT"
     CDS             complement(6094..6666)
                     /locus_tag="ctg52_6"
                     /transl_table=11
                     /translation="MDELKQIISKENFSSVIIDTCHPNDLVLQLIKSISCPVIILNSLE
                     TNVSDYNPGPILNQINNVSTLKHNVFQLSFTTFFDVGKHCIWKKNEYIPLAIQEFKILY
                     LLYLNSNKIVCSEELIEYADLTGRSSLYVHISSLREKVEDNPGDPKILQTNLEKGTSYL
                     TVHIFVLKKKQTQKMSCKKDDPKIILK"
     CDS             complement(6856..7062)
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg52_7"
                     /transl_table=11
                     /translation="MSQEAIIRSWKDPFSRENSTQNPAGNPFSELKEAQMDKLVGAGDM
                     EAACTFTLPGGGGVCTLTSECIC"
     CDS_motif       complement(6937..7062)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence:
                     MSQEAIIRSWKDPFSRENSTQNPAGNPFSELKEAQMDKLVGA"
                     /locus_tag="ctg52_7_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(6856..6936)
                     /prepeptide="core"
                     /locus_tag="ctg52_7_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-2.00"
                     /molecular_weight="2400.8"
                     /monoisotopic_mass="2399.0"
                     /core_sequence="GDMEAACTFTLPGGGGVCTLTSECIC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSQEAIIRSWKDPFSRENSTQNPAGNPFSELKEAQMDKLVG
                     A"
                     /leader_location="[6936:7062](-)"
                     /alternative_weights="2418.8"
     CDS             complement(7348..8082)
                     /locus_tag="ctg52_8"
                     /transl_table=11
                     /translation="MKNILFVERLKLKRSKLWIIYLLGPLLGVSLAYTNFIKNYNLFMN
                     PGDNPWVEAWTQVALFMGPFVLPIVVGIFAALVCRGEHVGGGWKQLLALPVKHSDIFLG
                     KFLTVVRMIFISMSILILLFIGFGYMLGISGSLPLLTILGYGIRGILACLPLILLQLIV
                     SIRSKTFGIPLAVSIVFTLPAIIIASTPLGQVYPWTQPMLAMSPEDESPIQSNFLFYSI
                     MVITCLGLLVYGIRSFTKRDLT"
     CDS             complement(8099..8857)
                     /locus_tag="ctg52_9"
                     /transl_table=11
                     /translation="MKKLLWADQLKLKRSSLLIVVLLVPLLIIAYELVNLTYRSEYVEK
                     QAEMFHAGSMWMYLLYDNSLLFGLGFPLAATLSASIIANIEHQANGWKQTLSFPVSRMR
                     IYVSKFICLVVSLFISSTIFLLGMVLLGKLVGFEGSVPWGLLFGDSYSMLVTVLPIMAF
                     QIWLSMVFSNQAFSILVGSVSSIMGLFLAAAQSTRWFPLAYPSQSSTVILQYEGIGYNP
                     DLSSYLCISLFLGIIILFLGSIHFAKRDAL"
     CDS             complement(8854..9765)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 184.7; E-value:
                     3.7e-56)"
                     /gene_kind="transport"
                     /locus_tag="ctg52_10"
                     /transl_table=11
                     /translation="MNDQIVVTHDLTKKYKKHTSVDGLNLRIRRGEIYGFLGPNGAGKT
                     TTIRMLLGLIKPTKGNIEIFGQNLNKNRLQILQRIGSLVESPTYYGNLTGYENLEAVRR
                     LRGLPEQQVNEVLETVRLSKVANRLTKEYSLGMKQRLGIAVALLSSPDLLILDEPTNGL
                     DPSGIQEIRELIKELPKSGMSVIVSSHLLSEIDQMATQVGIINNGKMIFQDSIASLHQK
                     RKPLLKVGVSDVIEAKTILNRKGLKVDLQKNYLWLSQTEPEFVSEINSILLHSGLSVFR
                     LEEKTRSLEDIFLELTGTEGSL"
     CDS             10008..10730
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 177.2; E-value: 6.2e-54)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg52_11"
                     /transl_table=11
                     /translation="MTLEENKILMVDDDEHILNLLITCFEKEGFSNISTAMTGSETLLK
                     IDQELPNIILLDVMLPDTDGFTLCSKIRSHTNVPILFLTAKTTDLDKLQGFSFGGDDYI
                     TKPFNPLEIVARVKAQLKRTTQLSSSYPLKQVYDYEYFKIDPNTGRLVVNGTRIDCPAQ
                     EMKLLIYFCEHPNQILSKHQIYKDVWGEFYGGDSTVMVHVRRLREKLEEDPSRPRWIKT
                     VRGQGYIFEAEPIDEDLF"
     CDS             10727..12166
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 163.7; E-value: 1.5e-49)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg52_12"
                     /transl_table=11
                     /translation="MKLRNRIAFYFVSRLFLLMFIWGLLMVGSIIFFSLVLGQNKMETP
                     HLSLKKIVAQTVVADKQFSINTKAKEDLLENRMWIQILDEQGDEVFSFNKPKNIPKHYI
                     LGELISDYMYPAKKGYQLSTWYETKNNQDLTWVLGKPMEKNNPFFYWVNNLWIVSIIMA
                     GIVIAIFYGKKLGAPLLFIVSWIENLSKEKYEEPYDRKFHSSKYRHNKSGYKTYQELMQ
                     ALSELTATLQRNKAERELLEKTREEWMAGVSHDLKTPLSVIKGYTVLLSSNEYEWENQQ
                     VRDFSLIMEERVEYMEKLIEDFNLTFQLKNESLPIHLEEKNVVKVIHDTLEKMKLLPES
                     ENKRFALESSHNKILFNMDERYLKRAVENLIANCIKHNPPGTKIKVILYQDVLHDNEIQ
                     ITIEDDGIGMDEETVECLFDRYFRGISASSNNSGTGLGMAIAQQIIKAHGGNIDIYSQP
                     GVGTRFKITFPNPPSKYNNVN"
     CDS             12265..12996
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 177.2; E-value: 6e-54)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg52_13"
                     /transl_table=11
                     /translation="MMAPKSRILLEDGCMNKIMIVEDSEDIRGLLQNYLEKYGYQTVVA
                     ADFTAVLDVFLREKPDVVLLDINLPAYDGYYWCRQIRQHSTSPIIFISARSGEMDQVMA
                     IENGGDDYIEKPFSYDIVLAKIKSQIRRAYGEYAAKQGEKVVEYAGVQLFVERFELRFQ
                     DEKSELSKKESKLLEVLLERGEKVTGRDRLMEKTWDTDIFIDDNTLNVYITRLRKKLRE
                     LNAPVSIEAVRGEGYQLRAQS"
     CDS             12993..13970
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 88.8; E-value: 7.2e-27)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg52_14"
                     /transl_table=11
                     /translation="MKLFLRSHAVLILLFLLQGLFVFFYYWFAGLHSFSHLFYILGVQL
                     LILAGYLVYRWYKDRGVYHWLSSGQEGTDIPYLGSSVFCSELYEKQMELIRLQHQKLHE
                     TEAKLDARVTYMNQWVHQVKTPLSVINLIIQEEDEPVFEQIKKEVRQIEFGLETLLYSS
                     RLDLFERDFKVEAVSLSELLQSVIQSYKRFFIQYRVYPKMDIRDDHQIYTDAKWLKFAI
                     GQVVTNAVKYSAGKSDRLELNVFRDEDRTVLDVKDYGVGIPPQDIKRVFDPYYTGENGR
                     RFQESTGIGLHLVKEITGKLNHTVDISSSPGEGTSVRFSFLTKM"
     CDS             14114..14887
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 212.6; E-value:
                     1e-64)"
                     /gene_kind="transport"
                     /locus_tag="ctg52_15"
                     /transl_table=11
                     /translation="MANMLEVKHINKTYKGQVSYQALKQISFSIEEGGFTAVMGPSGSG
                     KTTLLNIISTIDRPDSGDILIHGENPHRLKRTKLAHFRRKQLGFVFQDFNLLDTLTIGE
                     NIMLPLTLEKEAPSVIEEKLHGIAAKLGIENLLNKRTFEVSGGQRQRAAIARAVIHKPS
                     LILADEPTGNLDSKATKDVMETLQSLNRDDHVTALMVTHDPVAASYCRRVIFIKDGELF
                     NEIYRGENRQVFYEQILDVLSMLGGNANDLSSVRL"
ORIGIN
        1 cccccccccc cccccccccc cccccccccc cccccccccc cccccccccc cccccccccc
       61 cccccccccc cccccccccc cccccccccc cccccaccac cccccccccc gaccccccgc
      121 gtattgaagc aaaaatgtaa aattacgttg agcaaaaact gtcaattata ttctagcgtt
      181 tacattgcta tgcgctgacg ctgccctcct gataacatac tgccattttc cccgataatt
      241 gtgttatatc cattggcatt cttattatat cttcatgtaa ctgcactctc tttgctgctt
      301 gttcaatttt atcctgagat aagcttttaa atccagctat attgtttgca atagtatcat
      361 tgaaaagaaa gctttcttgt aatacgaccc ccatttgttt tcggagctcg taaaggttta
      421 aattcttcaa gtcctgttca ccataaaata cttttccctt agtgggtttg tataacccca
      481 gtataattct tgataaagtt gtctttccac tacctgtacg gcctacgaga gctaatttag
      541 tacctgactt aatgtttaat gaaacttctt taagaatatg taagctatga tgtgtaaatg
      601 tgacattttc aagttttata tcttgttttg atagttcagt ttcaattatt gaagtttggt
      661 tgatttgttc gggctcagtt tccataacat cttgcattcg ttcaaaagtg tcaccgacca
      721 attgaaattg ttgcatgctt gttattaaag aagcaatcgg caacaagaaa gatgttccta
      781 aactgctaaa ccctaataag cctccgagtg ttaaatttcc ggtgataact tcttttgatc
      841 caaaccataa taagagaagg ggtgcacaat atcggatgct tatacttatg ctatccatta
      901 tagcgtctaa gtggtatcgc tgtgaaaatg cttcgatttg tttatcatag taatttgacc
      961 actttgttag gatagaatga tctaaaccat ttgatttaat aaaagtgata gctcttagag
     1021 cttccactaa aaaactttgt gtggttgttt gaattgataa gtcattatgg attaaatttt
     1081 ttattcttgg aatcaaaatc atcattagta agaattgaat aattgccaat ccaatagcaa
     1141 aaaatgcaag cttaaatgat tgagttaaca tagcaataaa aaatgaaatc agagtaataa
     1201 tatctagtac tactgttgct ccattcttag ccataatctc ccttatcatg gaaatgttac
     1261 ttactctcat tgcaatatca ccggttgttc gattttcata aaaattaaga ggtaatttta
     1321 ataaatgttc cacaaaatcg tttgaaatgc ttttacttat aatagcttga agtttaattg
     1381 tgaaataatt gcggataaac ataacaagtc ccaatataaa aactgctatg atgactacaa
     1441 ttcctaaaaa tagaaaagaa tttgttgatt tacttattaa agaatgatcc actaaatatt
     1501 taattaaaaa aggaacggct aagaagacta cttgtgtgat cagtgaaaag aaaatgataa
     1561 gtgaaacaat agtacggctt ttaactatat aacgtaaata atactttgct gcgggtgatg
     1621 gcatcatcat ttatctgact tcttaaaagt caagattacc ttgctataat gtcttttaaa
     1681 ttcttcttcg gataatttca attttcctct gttggggtca attatatgaa aaagaccttt
     1741 tttaatctgt tctaaaacca caaagtgccg ttcatcccaa aatatgatgc agggaagata
     1801 tgaattgata tattttttca aatctttaaa cgaaacttgg tatactttgc agttaagccc
     1861 ataatattct gatactgatt ttaaaatgga tacagatacg ccatttcttt gggcatcaca
     1921 ttgttcactt attttattta gagatatagt actcccataa taacttaaaa tcatggtgag
     1981 acaggcgggc ccacactcat attgtcccat ttgccttact agaggaactc ttcttctcat
     2041 tggatcactc ctaagaaata gagccttaac aaagtaaggc tcattttaat tttacaattt
     2101 tagttctaaa ggtgattgga gtctcaaaac tgatggcact tcagtcggtg caaaaatctt
     2161 aagcaatcca agtcctatac ctgcataccc catcattaag gatggggatt cgttattttt
     2221 ttcaaatcca gttaaccatc ctctgagctt tatatcattt aaaattttat ggcttagttc
     2281 tgttacattt acgcttaact ttttattaaa gttttccgct gcgtacataa ggatgtccag
     2341 attacctaaa tcaccatggc ataaagaatg atcatgttca aaaccatatt ttagggttgt
     2401 attaattgcg acatgtgctt catcttttat caattcattt tgattgtgtg gcaggatcaa
     2461 tatcctactt aatcctatgc ctgctgcgcc attacaccaa gcaacaaaat tatcatttcg
     2521 aaactgtccg ttttcaagtt taatatctgc ccaattgttt ttttccggaa taaacaaagt
     2581 tctttcaaat tctaacgctt tttcagctac ctctttaaat acagtttgct cagtaattgc
     2641 gtaaatctca taaagagccc atataattcc tgaggcacca tgagcaaatc cggaggctgg
     2701 cgttgggttt gccgggactt tccatccaac tcccttttcc ataacgttta tattttgaat
     2761 aagacgattt ccgcattttg taatcaagtt taagatttgt tcttctttat accgtttaaa
     2821 caaatttatt aaaataactg ctgtcccagc cacccctgtt aaaatatcgt tgttttcatc
     2881 cctttcgatc aaagaatcta atttgttgag ggcagaataa agttcgtttt tcaatagttg
     2941 ttcatcattc cataattttg ataaatgatc caacaaataa aggtaagaag caattccccc
     3001 aaaggcacct aaatcactag atgcagacat atttttgtgt actgccacta aagctttttt
     3061 agatagattg gtgtattttt cattgttaga gaggcgacct aaataagcaa ggaagagaga
     3121 aataccacct acaccctcgt ataatgaact atttgcagct gaaatcttga attgatcctc
     3181 tcgttgattg tcaacaaacg atccgatcca agatacatcc tcttgtccat ctaactgttc
     3241 accttcaatc gccctactag caagaaagtc tccgatttta atagcttctt gaaaaaaatc
     3301 ttttgggtta aaaacgtgta atcgaggatt tatatcaaat actttatgtt tacgataaga
     3361 atccttaatt actaaaatag ctgtttttat aaagcttact tgttcatgac agtcactttc
     3421 attcatttca tttatttttt cctttgtctc atttaaggca cttgttttaa aaaaattgtt
     3481 gatttttcga ccgctggaat cccacatatt tgtagattca ggcttgcttg tgaaatatgg
     3541 gatatcccca aggaataagc cttccttttc actatttaca acttggttca atcgtggatt
     3601 caattttgta tctagccaca atttatctaa aatcatttca cgatctaagc cgtctctcat
     3661 gaaatctgga tgtaaactta ttttcagaag gtttgcatag cgagatgtac cacgcaatat
     3721 ttgtcttaca gtaacccctt taaaagaatc tatttgttcg agcatgtctt gtttatattt
     3781 catgaaaagg aagtaggttt cttcaaatcc ttttataata tttccttcgt aagcaacagt
     3841 attaatgatt tgtccatgca gcataggtct atgctgacta actggaattg gaaagttttt
     3901 ttcttctatc ctgactgtat ctttatctcg atcaactatt gtactggttt tatgcggaga
     3961 tacttgtcct tcttgtgcac ctaatgcact aaggtcaatt ccttcaaatc cagctttact
     4021 atttattttt ctcggtaata acccaattcg taaaactgac cgttcaatat gttcttgtgc
     4081 gcgactaaaa gcactggtat ctgtatacgt agaattatta tgaaataaag attctaaatc
     4141 aactaaaata ggatattctc catcagcaat taaattttgc atatgaaaat ctaccgcatt
     4201 cattgcatat aagatagcca aataacttcc aatacgccaa taaaactttc caatttgcag
     4261 ttcttcctga cattctttat aagagataaa ctgcgtccat ccataagatt ttttgttaag
     4321 tgtgtgtaca gtttttaagt caaaacttaa atttttacca tttagataat ttacaaattt
     4381 attaaatttt acgtctattt ctaatgaacg aggcttatac acaattttaa ttccagtttc
     4441 aaagtttaaa atggcgactg tttttccttt gttatgagta tctgagacgc cacttcctgt
     4501 atcgatggaa ataattttcc ctaatttttg accattacta aactcagatt ctaatatccc
     4561 tttatcctga tgaaatctta caaggagatc agaagtattt tgaatccaat acattgtttt
     4621 tgttgctaac agccttgtta aaactatgta ttcttctcga attgatcgaa catatgccgg
     4681 gtcatttaaa agggcttgat tgaaataaga ggctcgttct tcagaagttt caccccgcag
     4741 ctttcctgat acccttgcta catttaactc caatattaat atccgactac ttatagctga
     4801 taaagtttca ccaagattat taagtaaatc atcaattacc gacggactaa gttcttcctt
     4861 tatcagagat ttagtagagt gagaatataa tacttcctct aatttgcctc ttgctatttt
     4921 caaaaatggt tttataaaac taaagaagag aatatctttt ctaacttcta tatttacatt
     4981 tttataggat tgttcatcaa ctagctgaat aatttcaagc catccttgat gatcaccttc
     5041 attaataaat tccacttctt ttgcattgat agtatgcttt agggtttctt cgtcaatatt
     5101 ttgggtggct aatacatcct caattcgaat cccctcatca ctttcaacaa ggcttttcca
     5161 tctttcgaag cgtctgtttg ttagttcatc ccaattagta ttaagtgaac gccttacttt
     5221 tctttcactt atcgaagaag acctattcca taccgaattc cgtttgaatt ttgtatgcat
     5281 attgaacacc tcatttttaa taaatttgaa caattaatat tccttaatta tccataaata
     5341 tagcagagcc atttaaaagt taaaagaatt ttaaaagaag tttaggttta ttttatatgt
     5401 gtttattaag aatatttaat atttggaata aacaccacaa aaagaataat tgtgtagtat
     5461 gattgtttaa aatttacagg gggagaaaaa aatgagtatt tcaatattaa aagataaaaa
     5521 gttattgatc gggatttgcg gatcaatctc atctgtcggc atctcctcgt atctcttata
     5581 ttttaaaagc ttctttaagg aaataagggt tgttatgaca aaaacagcgg aagaccttat
     5641 tccagctcat actgtttctt atttttgtga ccatgtatac tcagaacatg gggaaaacgg
     5701 aaaaagacat agccacgtag aaattggccg ctgggcggac atatattgca ttattccagc
     5761 tacagcgaac atcttaggac aaactgctaa tggtgtagca atgaatttag ttgcaactac
     5821 tgtattagct catccatata acactatttt ctttcctaat atgaacgatt taatgtggaa
     5881 taaaacagtt gtttccagga atattgaaca attaagaaaa gatgggcata ttgttattga
     5941 accagttgaa attatggcgt ttgagattgc gacgggtaca agaaaaccta atcgtggtct
     6001 aattacaccc gacaaagctt tattagcaat agaaaaaggt tttaaagaaa gaacaaaaca
     6061 cccctcacta acataaatgg gatgactcaa aagtcatttt aaaatgattt ttgggtcatc
     6121 ctttttacac gacatttttt gagtctgctt ttttttcaag acaaatatat gtactgtcag
     6181 ataagaggta cccttttcca aatttgtttg aagaatcttt ggatctccag ggttatcctc
     6241 tactttttct ctaagagaac taatgtgtac ataaagactt gacctaccag taaggtcagc
     6301 atattcaata agttcttcag aacagactat tttatttgaa tttaaataaa gcaaatataa
     6361 aattttaaat tcttgtattg ctagagggat atattcattc tttttccaaa tacaatgctt
     6421 tccaacgtcg aaaaaagttg tgaaagacaa ttgaaaaaca ttatgtttta gggttgaaac
     6481 attatttatt tgatttaata ttggaccagg gttataatct gaaacgttag tttctaagga
     6541 gttaagtatt atgactgggc aagatatcga ttttatcagt tgcaacacta agtcattagg
     6601 gtggcaagta tcgatgatta cagaggaaaa attttctttg gatattattt gttttagttc
     6661 atccaatgtg ttaacattta ttatttcaat ctggcgttaa taaatgattc atatatgctt
     6721 ggaaatagct attttctgaa caaacgagag ttttccccaa tgatttaccc tcctgttttt
     6781 taagaatttt ctaatagttt atataataaa atataggctg ttccttctga agggaaacag
     6841 cctatataaa tcaaattaac aaatacattc agaagttaga gtacaaacac cgccgccacc
     6901 aggcaatgta aaagtacatg ctgcttccat gtctcccgca cctactaact tatccatttg
     6961 tgcttctttc agctcactga atgggttacc agctggattt tgtgtagaat tttcacggga
     7021 aaaaggatct ttccatgaac gaatgatagc ttcttgactc attgtattca cccccttatt
     7081 aagtatagta ttatattaac tcataatcaa aaaaatggaa gagatattat taaatgtaaa
     7141 aaaatgttta aataaagagt cttaagatat ctttatattt cttatgtctt atgctttgaa
     7201 acatcacctt ttccattagt cgtttagttt caaagaatac aaccaaaaag atttagtctt
     7261 accttcatat aaatttctgt tttacatagc gctagtcaaa ttagtttacc ttgtctcgaa
     7321 ttctcataag tttataccgc atatacccta cgtaaggtct cgtttagtaa aacttcttat
     7381 tccgtaaacc aggagaccga gacacgttat taccataatt gagtaaaaca ggaaatttga
     7441 ttgaatcggt gattcatctt cgggtgacat tgctaacata ggctgtgtcc atggatatac
     7501 ttgacctaat ggtgtactgg caataataat ggccggtaat gtaaaaacaa tgctaacagc
     7561 gagtggtatg ccaaatgttt tagacctgat tgaaacaata agctgcaata aaattaatgg
     7621 taaacaagct aagatccctc taattccata acctagaatt gtaagtaaag gaagactccc
     7681 gcttatgcct aacatataac cgaatccaat aaataagagg attaaaatgg acatactaat
     7741 gaatatcatg cggaccactg ttagaaactt tcccagaaag atatctgagt gtttgactgg
     7801 taaggctaga agctgtttcc aaccgcctcc tacatgttcc cccctgcaaa caagggcggc
     7861 gaaaattccc actacgatag gcaatacaaa aggacccata aataaggcaa cttgtgtcca
     7921 agcctctacc cagggattgt ctccgggatt cataaaaagg ttatagtttt taataaagtt
     7981 agtgtatgcc agggatacac ctaacaaagg ccctaataag tagatgatcc ataactttga
     8041 tcgcttaagc tttaaacgtt ctacaaataa aatgtttttc aagtatttcg cctccttttt
     8101 acaaagcatc ccgtttagca aaatgaatag agcctagaaa taatataatt atccctaaga
     8161 aaaggctaat gcaaaggtaa gatgaaagat ctgggttata tcctatacct tcatactgca
     8221 gaatgactgt cgaagattga ctaggataag ccagcggaaa ccatctcgtt gattgagcag
     8281 ctgccaaaaa caaacccatt atagatgata ctgatcctac aagaattgag aatgcttggt
     8341 tgctaaacac catagataac catatctgga atgccattat aggcagtact gtaactaaca
     8401 tgctgtaact atctccaaac aaaagtcccc aaggtacact gccttcgaat cctaccagtt
     8461 tgcccagcag taccatgccg agcaagaaga ttgttgacga aataaataaa ctgactacta
     8521 agcaaataaa tttacttaca taaattcgca ttctagatac aggaaaagaa agggtttgct
     8581 tccatccgtt tgcttgatgc tctatatttg ctattattga cgcagaaagt gtggcggcta
     8641 atggaaaacc cagaccaaat aacaaactgt tatcatacag taaatacatc cacattgatc
     8701 cagcatggaa catttcagct tgtttttcca cgtattcaga tcgataagta agatttacca
     8761 actcatatgc tataatgagt aagggaacca ataagactac aatcaataac gacgaacgtt
     8821 tcagttttaa ttgatctgcc cataataact ttttcataga cttccctctg taccggttaa
     8881 ttctaaaaaa atatcctcaa gtgatcgtgt cttttcttca agtcgaaata cagacagccc
     8941 tgaatgaaga agtatggaat tgatttctga aacgaattcc ggttctgttt gagacagcca
     9001 caaataattt ttttgtaaat caacctttaa tcctttcctg tttaatattg tttttgcttc
     9061 gattacgtca ctaacaccga cttttaatag tggttttctt ttttgatgta aacttgcaat
     9121 cgagtcctga aaaatcattt ttccattgtt gataattccc acttgagtag ccatttgatc
     9181 tatttcactc aataagtggc tggatacaat aacactcatt cccgatttag gcaattcttt
     9241 aattagctct cttatttctt ggataccgga tggatctaaa ccatttgtcg gttcatccag
     9301 aattaataaa tcaggactgc ttaacagggc aactgcaatt cccaaacgtt gtttcattcc
     9361 aagggaatac tccttagtca gtcgatttgc tactttagat aaccttacag tttccaatac
     9421 ttcattgacc tgttgttccg gaagtcctcg taacctccta acagcttcta agttttcgta
     9481 acctgttaaa ttaccataat aagttggaga ttctaccagt gacccgattc tttgcaatat
     9541 ctgcaaacga ttcttgttta ggttttggcc aaagatttcg atgtttcctt ttgttggttt
     9601 aattaaacct aataacattc ggatggttgt tgttttacca gcaccattcg gtccaagaaa
     9661 accataaatt tcgccgcgcc taatccttaa gtttaatcca tcaacagaag tatgcttttt
     9721 atacttttta gtcagatcgt gtgttaccac tatttgatca ttcatttgtc tctcacctca
     9781 cttttatcat aagcgatgtt ctttaaacac aaacgaaact cttcctaaac attcacttaa
     9841 cgacatccct ggtttatttt ctgtatgtag ttatattgat acctgaatat caaggttaaa
     9901 aattcgaaag aatattctga acccttaacg aaagttaaat tctttccttt tctgaccttt
     9961 atgtcattga tctcatataa aataagaaat aaaaaggagg gtaacttatg acgttagaag
    10021 agaacaaaat cctcatggtg gatgatgacg aacatatctt aaacttatta ataacttgct
    10081 ttgaaaagga aggtttcagc aatatttcca cagctatgac agggagcgaa acccttctga
    10141 aaatcgatca ggaacttcca aatattattt tattagatgt catgcttccg gacactgatg
    10201 gcttcacctt atgcagcaaa atacgctcgc atacaaatgt gccgatactc ttcttaacgg
    10261 caaaaacaac agatttagat aaattgcaag ggtttagttt tgggggagat gactatatta
    10321 ctaaaccatt taatccacta gaaattgtag ctcgtgtaaa agcccaatta aagagaacga
    10381 ctcaactctc ttcttcttac cctctaaaac aggtatacga ttatgaatat tttaaaatag
    10441 atcccaatac cggaagactt gttgttaacg ggacaagaat agattgccct gctcaggaaa
    10501 tgaaacttct gatttatttc tgtgaacatc ccaatcaaat tttaagtaaa caccaaattt
    10561 ataaagatgt gtggggggag ttttatggcg gagatagtac tgtaatggta catgtaagac
    10621 gattacgtga aaaattagag gaagacccga gcagacctag atggattaaa acggttcgag
    10681 gacagggcta tatatttgaa gcagagccta tagatgagga tttattttga agctgagaaa
    10741 taggatagca ttttacttcg tatcgagact ttttttactc atgtttattt ggggtctgct
    10801 catggtgggc agtatcatat ttttcagcct cgtcttaggt caaaataaaa tggaaacgcc
    10861 gcacttatcc ttaaaaaaaa ttgttgccca aacagttgtt gcagataaac aattttccat
    10921 aaatacgaaa gcaaaagaag atttattaga gaatcggatg tggattcaaa ttttagatga
    10981 acaaggagat gaggtttttt cttttaataa acctaaaaat atacctaagc attatattct
    11041 tggagaatta atatcagatt acatgtatcc tgccaaaaaa ggttatcaat tatctacgtg
    11101 gtacgaaacg aaaaacaatc aggatttaac atgggtattg ggaaagccga tggaaaaaaa
    11161 taaccctttt ttctattggg tgaataactt gtggattgtt tctattatta tggcaggaat
    11221 tgtcattgca atattttacg gaaaaaaact aggtgctccc ctgctgttta ttgtatcttg
    11281 gattgagaat ttgtctaaag aaaaatatga agaaccttat gatcggaagt ttcattcaag
    11341 caaatataga cataataaat ctggatataa aacctatcaa gaattaatgc aggctctgtc
    11401 tgaacttacc gcaacgcttc aaaggaataa ggctgagcga gaattattgg aaaagacacg
    11461 agaagagtgg atggccggtg tctcacatga tttaaaaacc cctctttcgg ttattaaggg
    11521 atatacggtt cttttatctt caaatgaata tgagtgggaa aatcagcaag tgcgtgattt
    11581 ttccttaata atggaagaac gtgtcgaata tatggaaaag ctgattgaag atttcaactt
    11641 aacttttcaa ttgaaaaatg agtcgcttcc aatccatctt gaagaaaaaa acgtagtgaa
    11701 agtaattcat gacactttag aaaaaatgaa gctgctaccg gagtcagaaa ataagagatt
    11761 cgctttagaa tccagtcaca ataagatact ttttaatatg gatgaaaggt acctaaagcg
    11821 cgcagttgaa aacttgattg ctaattgtat taaacataat cctccgggca ctaaaataaa
    11881 ggtcatatta tatcaggacg tgttacatga caacgaaata caaattacaa tagaagacga
    11941 tgggatagga atggacgaag agacggttga atgtttattt gatcggtatt tcagagggat
    12001 aagcgcttcg tcaaataact ccgggactgg attaggaatg gctattgctc agcaaattat
    12061 caaggcgcat ggtggaaata ttgatatata cagtcagccg ggagttggca caagatttaa
    12121 aattaccttt ccgaatccgc catctaagta taacaatgtc aattagaaat tacgttgaga
    12181 aagggtgaag cgggtctttt ataaaggctc gctttctcat gttgcagaga agcgatgaaa
    12241 gcattatgat gggggcatca aataatgatg gctccgaaaa gccgtatcct tttggaggat
    12301 ggttgcatga ataaaatcat gattgtggaa gacagtgaag acattcgcgg actattgcag
    12361 aattaccttg aaaaatacgg atatcaaaca gtggtcgccg cggattttac agctgttctt
    12421 gatgtctttt tgcgggaaaa gcccgatgtg gtgctgcttg atatcaattt gccggcatat
    12481 gacggatatt attggtgccg gcagatccgc cagcactcca caagcccgat catctttatt
    12541 tctgccagaa gcggggaaat ggatcaggtg atggcgattg aaaatggggg agacgattat
    12601 atcgaaaaac cgttttctta tgatattgtg cttgcgaaaa tcaaaagcca gatccggagg
    12661 gcgtacgggg agtacgccgc aaagcaggga gagaaagtgg ttgaatatgc cggcgttcag
    12721 ctctttgtgg aacggtttga actgcgtttt caggatgaaa aaagcgagct ttctaaaaaa
    12781 gaaagcaagc ttttggaagt gctgcttgag cggggagaaa aggtgacggg aagagaccgg
    12841 ctcatggaaa aaacgtggga caccgacata ttcatcgatg ataatacact taacgtgtat
    12901 atcacgcggc tcagaaaaaa actgcgggag ctgaatgcgc ctgtttctat tgaagcggtg
    12961 cggggcgaag gctaccagct gagggcgcag tcatgaagct gtttctccgg tctcatgcag
    13021 tgctgattct gctttttctc cttcaaggac tgtttgtctt cttttattac tggtttgcgg
    13081 gtcttcattc tttttctcac ttgttttaca tattgggcgt gcagcttctt attttggcgg
    13141 gctatcttgt ctatcgctgg tataaagacc gcggcgtgta tcattggctc agctcggggc
    13201 aggaagggac ggatatcccg tatctcggtt cctcagtgtt ctgttcagag ctgtatgaaa
    13261 agcagatgga gctgatccgg ctgcagcacc agaagctcca tgagaccgaa gccaagctgg
    13321 acgcgcgggt gacgtatatg aatcaatggg tgcaccaagt aaaaacgccg ctgtcggtca
    13381 ttaatttaat cattcaggaa gaggatgagc ccgtctttga acaaatcaaa aaagaggtcc
    13441 ggcagattga attcgggctg gagacgctcc tttattcatc aaggctcgac ctgtttgagc
    13501 gggattttaa agtcgaagcg gtgtccttat cagagcttct ccaatcggtc attcaaagct
    13561 ataaacgatt ttttattcaa taccgcgtct atccgaaaat ggatattcgc gatgatcatc
    13621 agatttacac cgatgccaaa tggctcaaat ttgcgatcgg ccaagtcgtc acaaatgcgg
    13681 tcaaatattc ggcaggcaag agtgacagac tggagctgaa tgtcttccgc gatgaagaca
    13741 ggacggtgct tgatgtcaaa gattacggtg tcggcattcc cccgcaagat atcaagcggg
    13801 tgtttgaccc ttattacacc ggcgaaaacg ggcggcgttt ccaagaatct acgggaatcg
    13861 gcctccatct cgtcaaagaa attacgggca agctcaatca tacggtggac atcagctcgt
    13921 cccccggtga agggacatcg gtccgatttt catttcttac aaaaatgtaa gactgcgtta
    13981 agaaaacaac atagctcatt ctgtttcccc ttgataacat ggatttacgt caaggggatt
    14041 tttatgttga acgtcccggc actacatgaa agcagcccag atcaacaaga ataaaaccat
    14101 aaggaggatt ctcatggcga atatgcttga agtcaaacat ataaataaaa cctataaagg
    14161 acaagtatcc tatcaagctt taaaacaaat ttcattttca atagaagaag gcgggttcac
    14221 ggcggtgatg ggaccgtccg gctccggaaa aacaacactt ttgaatatca tttcaacgat
    14281 cgaccggccg gattcaggcg atatcctgat tcacggagaa aacccgcacc ggctgaagcg
    14341 gacaaagctc gctcatttcc gccgcaagca gctcgggttt gtgtttcagg atttcaacct
    14401 cctggacacg ctgacaatcg gtgaaaatat catgctgccg ttaacgcttg aaaaagaagc
    14461 gccgtctgta atagaagaaa aactgcacgg catcgcggca aagctcggta tcgaaaacct
    14521 gcttaacaag cggacgtttg aagtatccgg aggccagcgc cagcgggccg ccatcgcaag
    14581 agcggtcatt cataagccgt cactcattct ggccgatgaa ccaactggaa accttgattc
    14641 caaagcgaca aaagacgtca tggaaacgtt gcagagcctg aatcgggatg atcatgtcac
    14701 ggctttgatg gtgacccacg atccggttgc ggcaagctac tgccgccgcg tcatctttat
    14761 aaaagacggc gaattgttta atgagattta ccgcggggaa aaccgccaag tcttttatga
    14821 acaaattctt gatgtgctgt ctatgctggg gggaaacgca aatgaccttt cttcagttcg
    14881 cttataaaaa cgtcacgaga aacaaaaggg cctatcttgc attcttttta agcagcgcct
    14941 tttccgtttt gattttcttt acctttgcga tgttcctgtt tcatccggca ttaaaggagg
    15001 gctacattaa aggagggcta cctgaataat atcgccaaaa aaggcttaac cgccgcggaa
    15061 tggatgatct ttgttttttc tttcttattt gttctgtatt cggttaacgc atttttgaaa
    15121 tcgagaaata aagaattcgg catcctgctc atgcagggca tcacgccggg gcagctgaga
    15181 aagctcatta cggcggaaaa tatgatcatc ggcgttatgt caattgcagc cggcattatc
    15241 ggaggggtca ttttttcaaa gacgttcttt acggtcggcg
//
