LOCUS       c00051_gnlPro..        13305 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OIDMAAEK_54.
ACCESSION   c00051_gnlPro..
VERSION     c00051_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 21:08:12
            Original ID  :: gnl|Prokka|OIDMAAEK_54
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 92978
            Orig. end    :: 106283
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13305
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[102978:105503]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12525
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13305
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13305
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             153..929
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ECH_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg51_93"
                     /sec_met_domain="ECH_1 (E-value: 4.8e-65, bitscore: 212.0,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNAISLAVDQFVAVLTIHNPPANALSSRILEELSSCLDQCETDAG
                     VRSIIIHGEGRFFSAGADIKEFTSLKGNEDSSLLAERGQQLMERIESFPKPIIAAIHGA
                     ALGGGLELAMACHIRIATEDAKLGLPELNLGIIPGFAGTQRLPRYVGTAKALELIGSGE
                     PISGKEALDLGLVSIGAKDEAEVFEKAKALAAKFAEKSPQTLASLLELLYSNKVYSYEG
                     SLKLEAKRFGEAFESEDAKEGIQAFREKRKPQFKGE"
     CDS             944..1717
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ETF"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 159.7;
                     E-value: 2.4e-49)"
                     /gene_kind="electron_transport"
                     /locus_tag="ctg51_94"
                     /sec_met_domain="ETF (E-value: 4e-49, bitscore: 159.7,
                     seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLFVLMKRTFDTEEKIVIETGKIQDDGAEWIINPYDEYAIEEAI
                     QLKEKHGGTITAVTVGGEEAEKELRTALAMGCDQAVLINIEDDLEEPDQYSISQVLYHY
                     MKDQEFDLILGGNVAIDGGSGQVAPRLAELLDIPCITTITKLEINGTDAEAERDVEGDV
                     EKMKTTLPLLVTAQQGLNEPRYPSLPGIMKAKKKPLEELELDDLDLDEEDAEPKLKTIE
                     RFLPPKKEAGKLLQGEPAEQAKELVSLLRSEAKVI"
     CDS             1753..2730
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ETF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ETF_alpha"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 153.3;
                     E-value: 2.2e-47)"
                     /gene_kind="electron_transport"
                     /locus_tag="ctg51_95"
                     /sec_met_domain="ETF (E-value: 3.7e-47, bitscore: 153.3,
                     seeds: 129, tool: rule-based-clusters)"
                     /sec_met_domain="ETF_alpha (E-value: 3.9e-38, bitscore:
                     122.2, seeds: 511, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKKVIVLGEIRDGELRNVTFEAIAAGRTISGDGEVIGVLIGENV
                     QSIAQELIHYGADKVLTAEDPKLKTYTADGYSQVMRGVIEQENPDSVIFGHTAMGKDLS
                     PKLAARLQTGLISDAIDVSVTGGNVVFTRPIYSGKAFERVISTDPMIFATIRPNNIQAS
                     EKDTSRSGSIESINVSLTDLRTVIQEVVKKTADGVDLSEAKIIVAGGRGVKSKEGFQPL
                     QELAEVLGAAVGASRGACDADYCDYALQIGQTGKVVTPDLYIACGISGAIQHLAGMSNS
                     KVIVAINKDPEADIFKIADYGIVGDLFEVVPLLTEEFKQLNIHS"
     CDS             2927..4435
                     /locus_tag="ctg51_96"
                     /transl_table=11
                     /translation="MKGMIRGMSEHQAVIQTDIVKGTINKNIYGHFAEHLGRGIYEGIW
                     VGTDSDIPNINGIRKDVLEALKQLHIPVLRWPGGCFADEYHWANGVGDRKTMLNTNWGG
                     TIESNEFGTHEFMMLCELLECEPYICGNVGSGTVQEMAEWIEYMTFEEGTPMSDWRKQN
                     GREEPWNLKYFGVGNENWGCGGNMHPEYYADLYRRFQTYVRNYSGNDIYKIAGGANVDD
                     FNWTDVLMKKAAGLMDGLSLHYYTIPGDFWKGKGSATEFTEDEWFITMKKAKYIDELIQ
                     KHGTIMDRYDPEQRVGLIIDEWGTWFDPEPGTNPGFLYQQNTIRDALVAASHFHIFHQH
                     CRRVQMANIAQTVNVLQAMILTEGERMLLTPTYHVFNMFKVHQDASLLATETMSADYEW
                     NGETLPQISISASKQAEGDINITICNIDHQNKAEAEIELRGLHKAADHSGVILTAEKMN
                     AHNTFDDPHHVKPESFRQYTLSKNKLKVKLPPMSVVLLTLRADS"
     CDS             4757..5071
                     /locus_tag="ctg51_97"
                     /transl_table=11
                     /translation="MAIVKATDQSFSAETSEGVVLADFWAPWCGPCKMIAPVLEELDQE
                     MGDKLKIVKIDVDENQETAGKYGVMSIPTLLVLKDGEVVETSVGFKPKEALQELVNKHL
                     "
     CDS             5207..6979
                     /locus_tag="ctg51_98"
                     /transl_table=11
                     /translation="MNKQLKEKLALLPDQPGCYLMKDRQQTVIYVGKAKVLKNRVRSYF
                     TGSHDAKTQRLVTEIEDFEYIVTSSNLEALILEMNLIKKHDPKYNVMLKDDKTYPFIKL
                     THERHPRLIVTRNVKKDKGRYFGPYPNVQAARETKKLLDRLYPLRKCSKLPDRVCLYYH
                     LGQCLAPCVKDISEETNRELVESITRFLRGGYNEVKKELEEKMNEAAENLEFERAKELR
                     DQMAHIESTMEKQKMTMNDLVDRDVFAYAYDKGWMCVQVFFIRQGKLIERDVSMFPLYQ
                     EADEEFLTFIGQFYSKNNHFLPKEILVPDSVDQSMIEQLLETNVHQPKKGPKKELLMLA
                     HKNAKIALKEKFSLIERDEERSIGAVQKLGEALNIYTPHRIEAFDNSNIQGTNPVSAMI
                     VFIDGKPYKKEYRKYKIKTVTGPDDYGSMREVVRRRYTRVLRENLPLPDLIIIDGGKGQ
                     INAARDVIENELGLDIPIAGLAKDEKHRTSNLLIGDPLEVVYLERNSQEFYLLQRIQDE
                     VHRFAISFHRQIRGKSAFQSVLDDIPGIGEKRKKMLLKHFGSVKKMKEASLEDIKKAGV
                     PTAAAQLLYDKLQK"
     CDS             7349..8575
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AA_kinase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg51_99"
                     /sec_met_domain="AA_kinase (E-value: 6.6e-56, bitscore:
                     182.3, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLIVQKFGGTSVGSVEKIQNAANRAIAEKQKGHQVVVVVSAMGK
                     STDELVSLAKAISDQPSKREMDMLLATGEQVTISLLSMALQEKGYDAVSYTGWQAGIRT
                     EAIHGNARITDIDTSVLADQLEKGKIVIVAGFQGMTEDCEITTLGRGGSDTTAVALAAA
                     LKADKCDIYTDVPGVFTTDPRYVKSARKLAGISYDEMLELANLGAGVLHPRAVEFAKNH
                     QVPLEVRSSTETEAGTLIEEESSMEQNLIVRGIAFEDQITRVTIYGLTSGLTTLSTIFT
                     TLAKRNINVDIIIQTQAEDKTGISFSVKTEDADQTVAVLEEYKDALEFEKIETESKLAK
                     VSIVGSGMVSNPGVAAEMFAVLAQKNILIKMVSTSEIKVSTVVSENDMVKAVESLHDAF
                     ELSKHPSAV"
     CDS             complement(8619..9065)
                     /locus_tag="ctg51_100"
                     /transl_table=11
                     /translation="MKSKFEESIDNLKEIEMNAYAYELIREIVLPDMLGQDYSSMMYWA
                     GKHLARKFPLESWEEFPAFFEEAGWGTLTNVSAKKQELEFELEGPIISNRLKHQKEPCF
                     QLEAGFIAEQIQLMNDQIAESYEQVKKRADKVVLTVKWDMKDPV"
     CDS             9359..9967
                     /locus_tag="ctg51_101"
                     /transl_table=11
                     /translation="MSGNREFYFRRLHSLLGVIPVGIFLIQHLVVNQFAARGAEAFNSA
                     AHFMDSLPFRYALEIFIIFLPLIYHAVYGVYIAFTAKNNAGQYSYMRNWLFVLQRVTGI
                     ITLIFVSWHVWETRIAAQMGAEVNFDMMANILSSPAMLGFYIVGVLSTIFHFSNGLWSF
                     AVTWGITVTPRSQRISTYVTLIIFVALSYVGLKAIFAFV"
     CDS             10001..11761
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 296; E-value:
                     1.7e-90)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg51_102"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.9e-90, bitscore:
                     296.0, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 8.2e-43,
                     bitscore: 138.2, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQSSIIVVGGGLAGLMATIKAAESGMAVKLFSIVPVKRSHSVCA
                     QGGINGAVNTKGEGDSPWEHFDDTVYGGDFLANQPPVKAMCEAAPSIIHLLDRMGVMFN
                     RTPEGLLDFRRFGGTQHHRTAYAGATTGQQLLYALDEQVRRYEVAGLVTKYEGWEFLGA
                     VLDDDRTCRGIVAQNLTNMQIESFRSDAVIMATGGPGIIFGKSTNSMINTGSAASIVYQ
                     QGAYYANGEFIQIHPTAIPGDDKLRLMSESARGEGGRVWTYKDGKPWYFLEEKYPAYGN
                     LVPRDIATREIFDVCVNQKLGINGENMVYLDLSHKDPKELDIKLGGIIEIYEKFMGDDP
                     RKLPMKIFPAVHYSMGGLWVDYDQMTNIPGLFAAGECDYSMHGGNRLGANSLLSAIYGG
                     MVAGPNAVKYVNGLESSAEDMSSSLFDAHVKKEEEKWADIMSMDGTENAYVLHKELGEW
                     MTANVTVVRHNDKLLKTDDKIQELMERFKKININDTTKWSNQGAMFTRQFSNMLQLARV
                     ITLGAYNRNESRGAHYKPDYPERNDDEWLKTTMAKHVSPYEAPEFEYQDVDVSLITPRK
                     RDYSKKKVAK"
     CDS             11764..12525
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 96.2; E-value: 3.7e-30)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg51_103"
                     /sec_met_domain="Fer2_3 (E-value: 6.2e-30, bitscore: 96.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 2.3e-11, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00042, bitscore: 13.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEQKTIRFIITRQDTADSTPYDEEFEIPYRPNLNVISALMEIRR
                     NPVNVKGEKTTPVTWDMNCLEEVCGACSMVINGKPRQSCTALIDQLEQPIRLKPMKTFP
                     VVRDLQVDRSRMFDSLKKVKAWIPIDGTYDLGPGPRMPEKRRQWAYELSKCMTCGVCLE
                     ACPNVNSKSKFMGPAPMSQVRLFNAHPTGSMNKSERLEALMDEGGLADCGNSQNCVQSC
                     PKGIPLTTSIAALNRDTNLQAFRNFFGSDRV"
     CDS             12585..13028
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg51_104"
                     /sec_met_domain="HBT (E-value: 1.3e-13, bitscore: 44.0,
                     seeds: 132, tool: rule-based-clusters)"
                     /sec_met_domain="HBT_2 (E-value: 4.8e-10, bitscore: 32.8,
                     seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLPAYIDMPFQEWKTSFSFFNKVSVRFSETDMFGHMNNVTPFIY
                     FEEVRISYFKKLNMMSENKQTMTVVASQQCDYLRQVMPYEELRIYVKTSAVGSSSLTLH
                     YLGENLEGEPCFTGAVVMVQVSKESGKAVSWTDEEKETLLHTR"
     CDS             13144..13305
                     /locus_tag="ctg51_105"
                     /transl_table=11
                     /translation="LKEKEFQSKPLLTKREREVFELLVQDKTTKEIASELFISEKTVRN
                     HISNGMHIV"
ORIGIN
        1 cgcctcgccc ggcagatgat ttttggaacg attgacgaaa ccgtgacaac ttgggtgatg
       61 aatgaccaaa agtacgatct cgctgcgctt tcagacagcg ttttagaatt attggtgtcc
      121 ggaattcata ataagtaaag gagttctgtc ctatgaatgc aatatcactg gcagttgatc
      181 aatttgtggc agttttgacg attcacaatc cgccggcaaa tgcgctttcc agccggatat
      241 tagaagagct gtcttcctgt cttgatcaat gtgagacaga tgcaggcgta cgaagcatta
      301 tcattcacgg cgagggaaga tttttctcag ccggcgctga tattaaagaa tttacatcgc
      361 ttaaaggcaa tgaggattcc tcattgctcg ctgagcgcgg ccagcagtta atggagagaa
      421 tcgaaagctt tccaaaaccg attatcgcag cgattcacgg cgctgctctc ggaggcgggc
      481 tggagcttgc gatggcctgt catatcagaa tcgcaacaga agatgctaag ctggggctcc
      541 cggagcttaa tctcggtatc attccaggtt ttgcggggac acagcgcctt ccgagatatg
      601 tcggtacagc caaagcactg gagctcatcg gatcaggaga accgatatcc ggaaaagaag
      661 cgcttgatct cggacttgtc tcaattggag cgaaagatga ggcagaagtg tttgaaaaag
      721 caaaagcact tgccgctaag tttgcagaga aaagcccgca aacgctggca tctttgcttg
      781 aacttcttta ttccaacaag gtgtattcct atgaaggcag cttaaagctt gaagcaaagc
      841 gatttgggga agcatttgag tcagaggacg ccaaggaagg catccaggca tttcgcgaaa
      901 aaagaaagcc tcagttcaaa ggcgaataaa aggggatatg atcatgaatc tatttgtact
      961 gatgaaacgg acgtttgaca cagaagaaaa aatcgtcatt gaaacaggaa agattcagga
     1021 tgacggagcg gaatggatca ttaatccata tgatgagtac gcgatagaag aagccatcca
     1081 gctgaaggaa aagcatggcg gcacgatcac cgccgtcacg gtcggcggtg aagaagcgga
     1141 gaaagaattg cgtacggcgc ttgccatggg ttgtgaccaa gctgttttaa tcaacataga
     1201 agatgatctt gaagaacccg accaatattc catttctcaa gttttatacc actatatgaa
     1261 ggatcaggag tttgatttga ttctcggcgg aaatgttgcc attgacggag gatcaggaca
     1321 agtggcgcct cggcttgccg agctactgga cattccgtgt atcactacga tcaccaaact
     1381 cgaaatcaac ggcactgatg cagaagcaga aagggacgtc gaaggggatg ttgaaaaaat
     1441 gaaaacgacg ctcccattgc ttgtcacagc tcagcagggc ttaaacgagc cgcgctatcc
     1501 atcgcttccg ggaattatga aggctaagaa aaagccgctt gaagagcttg aacttgatga
     1561 tcttgatctg gacgaagagg atgctgaacc aaagctgaaa accattgaac gttttctgcc
     1621 gccgaaaaaa gaagccggga agcttctcca aggtgagcct gctgaacagg caaaagagct
     1681 tgtttcattg ctccgcagcg aagctaaagt catttaaaac ttggacattc aaagaaacag
     1741 ggggatgtta gaatgggaaa aaaagtgatc gtgcttggag aaatacgcga tggggaattg
     1801 cgaaatgtca cctttgaagc aatagctgca ggaagaacca tttcaggaga tggggaagtc
     1861 atcggtgttc tcatcggtga aaatgtacaa agcattgcac aagagcttat tcattacgga
     1921 gcagataaag ttcttaccgc tgaggacccg aagctgaaaa catacacggc agacgggtac
     1981 agccaggtca tgagaggtgt tatcgagcaa gaaaatcctg attcagtcat cttcgggcat
     2041 acggcaatgg gcaaggatct ttcaccgaag cttgctgccc ggctgcaaac aggcttaatt
     2101 tctgatgcta tagatgtaag cgttaccgga gggaatgttg tgttcacacg gccgatttac
     2161 tcggggaaag cttttgaacg cgtcatttca accgatccga tgatctttgc aacaattcgc
     2221 cccaataaca ttcaagcttc agaaaaagac accagcagat cggggagcat cgaaagcata
     2281 aatgtctctc ttactgacct tcgcaccgtg attcaagagg tcgtgaaaaa aacggcggac
     2341 ggcgttgatc tctccgaagc aaaaattatc gttgcgggcg gccgaggagt caaaagcaag
     2401 gagggatttc agcctctgca ggagcttgca gaggtgctag gggccgcggt cggggcttct
     2461 cgcggggcat gtgacgctga ttattgcgat tacgcgctcc aaatcgggca gaccgggaaa
     2521 gtcgttactc cggatttgta cattgcatgc ggcatttccg gcgccatcca gcatttggcc
     2581 ggcatgtcaa acagcaaggt gatcgtcgcc atcaataaag accccgaagc cgatatcttt
     2641 aaaatagcgg attacggcat cgtcggtgat ttatttgaag ttgtcccgtt attaactgag
     2701 gaattcaaac aattgaatat acactcataa aggaaatccc ggactttaaa agttcgggat
     2761 tttttcatat ttataaatac atacgtacaa atataaaaac aatagaaaat gtcgttgaca
     2821 tgtacgaaca tatataatat ggttacttta aaagcgctta cattcatgct gactcctcag
     2881 gcaaaagaca gatcacatat ttgactgtgg tgcttttcat atccgtatga aaggaatgat
     2941 cagaggcatg tctgaacatc aagcagtgat tcaaacagat atcgtaaaag gaaccattaa
     3001 caaaaatata tacggtcatt ttgctgagca tttaggaaga gggatttatg aggggatctg
     3061 ggttggaacg gactcagaca tccccaatat caacgggata cgaaaggacg tgctggaggc
     3121 gctcaaacag ctgcacattc ctgtcctcag gtggccgggc gggtgttttg cggacgaata
     3181 ccattgggca aacggtgtcg gtgaccgtaa gacaatgctg aacactaact ggggcggtac
     3241 aattgaatca aatgaattcg gaacgcatga atttatgatg ctttgcgagc tgcttgaatg
     3301 tgagccatat atttgcggca atgtcggaag cggaaccgtt caggaaatgg cggagtggat
     3361 tgagtatatg acatttgaag aaggcacgcc gatgtcagac tggagaaaac aaaatggaag
     3421 agaagagcct tggaatctga aatatttcgg cgtgggtaat gaaaattggg gctgcggcgg
     3481 caacatgcat cccgaatact acgcagatct gtaccggcgt tttcagactt atgtccgcaa
     3541 ttacagcggg aatgacattt ataaaattgc aggcggagca aatgtggatg attttaattg
     3601 gacggacgtg cttatgaaaa aagccgctgg cctgatggac gggttgagtc ttcattatta
     3661 cacgattccg ggggatttct ggaagggcaa aggatcagcc acagaattca cagaagatga
     3721 gtggtttatt acgatgaaaa aagccaaata catcgatgaa ttgattcaaa aacacggcac
     3781 gattatggac cggtacgatc cggagcagcg ggtcgggctg attattgatg aatggggcac
     3841 gtggtttgat cccgagccag gcacgaatcc cggtttctta tatcagcaaa acaccattcg
     3901 tgatgcactg gtggcggctt ctcatttcca cattttccat cagcattgcc gccgggtgca
     3961 aatggccaac atcgcccaaa cagtaaatgt tcttcaagcg atgattttga ctgagggaga
     4021 gcggatgctt ttgacaccga cgtaccatgt attcaatatg tttaaggtgc accaggacgc
     4081 ttctctttta gccacagaga caatgtctgc cgactatgaa tggaacggtg aaacgcttcc
     4141 gcaaatcagc atttcagcgt cgaaacaagc tgaaggcgat atcaatatca caatttgcaa
     4201 catcgatcac caaaacaaag cagaggcgga aatcgagctg aggggcctac acaaggcagc
     4261 ggaccattcc ggagtcattc ttacggcaga aaaaatgaat gcgcataaca cgtttgacga
     4321 tcctcatcat gtcaaaccgg aatccttcag acaatacacg ctcagcaaaa acaaactgaa
     4381 agtaaaactc ccgccaatgt cagtcgtctt acttacgctg cgtgctgatt cttaatcgcg
     4441 caagaacgcc ggagcttcat gccggcgctc tttttcaggt tttaaaacag ctccggcagg
     4501 gcatggtaaa gtacatgaca gtgaagagga gatgtgatct ttgcttcgta ccattttaat
     4561 gattattggg gcaattgtag tgatcggggc cattatcaga tttgtgtttt aaaaaaagag
     4621 catatcccat tcaaccatat aaaaatgagt aaaccggctg tgatcaggaa aaaataattt
     4681 gtaagcatta aaatagcgtg aacgaatggg agatgctata ctaaaaatca tcatttcaca
     4741 ttggaggaat tcaataatgg ctatcgtaaa agcaactgat caatctttct cagctgaaac
     4801 aagcgaaggc gtcgtactgg cagacttctg ggctccttgg tgcggacctt gtaaaatgat
     4861 tgcacctgtt cttgaagaat tggatcaaga aatgggagac aaactgaaaa tcgtaaaaat
     4921 cgatgtagac gaaaaccaag aaactgccgg aaaatacggc gttatgagca tcccgactct
     4981 tcttgtgtta aaagacggcg aagtagttga aacttcagtc ggcttcaaac caaaagaagc
     5041 gcttcaagag cttgtaaaca aacatcttta attttccgct gcttacatgc cagagcgatt
     5101 ccgattgagg gatcgctttt tttattcgcc aattgtgaac catagagaaa aacaaacgtt
     5161 cgtgttaaac tggaaataaa ggattaaaca taaggaaggg taacatatga acaaacaact
     5221 gaaagaaaaa ctcgccctcc ttcctgatca accgggttgt tatctcatga aggaccggca
     5281 gcagactgtg atctacgtag ggaaagcaaa agtgctgaaa aacagagtgc gctcctactt
     5341 caccggttct cacgacgcga aaacccaaag gcttgtgacg gaaatcgagg attttgaata
     5401 tatcgtgacg tcctccaatc ttgaagcgct tattttagaa atgaatctga tcaaaaagca
     5461 tgatccgaaa tacaacgtca tgctcaaaga cgacaaaacc tatcctttca taaaactcac
     5521 ccatgaacgc cacccaaggc tgattgtcac acgcaatgtc aaaaaagaca aagggcgcta
     5581 tttcgggccg tatccgaatg tacaggcagc aagggaaaca aaaaaactgc tcgaccgtct
     5641 gtatcctctc agaaaatgct ccaagctccc ggacagagtg tgcctttact atcatctggg
     5701 ccaatgcctc gctccgtgtg taaaggatat ttccgaagag acgaacagag agctggttga
     5761 aagcattaca cgtttcttaa ggggcggcta taatgaggtc aaaaaagagc ttgaagagaa
     5821 aatgaatgaa gctgctgaga atcttgagtt tgaacgagca aaagagcttc gtgaccaaat
     5881 ggcccatatt gaatcaacga tggaaaaaca aaaaatgacg atgaacgatc tagtcgaccg
     5941 tgatgtgttc gcgtacgcgt acgataaggg ctggatgtgc gtgcaggtct ttttcatccg
     6001 ccaaggaaag ctcattgaac gcgatgtcag catgttcccg ctttatcagg aagcagatga
     6061 agagttcctc acgttcatcg ggcagttcta ttcaaaaaac aaccacttcc ttccgaagga
     6121 gattttagtt ccggacagcg tagatcaatc catgatcgag cagctgctgg aaacaaacgt
     6181 tcaccagccg aaaaaaggcc cgaaaaaaga actgctcatg cttgcccata aaaatgcgaa
     6241 aatcgcattg aaagaaaaat tctctttaat cgaacgggac gaggagcgtt caatcggggc
     6301 agtgcagaaa ctaggtgagg cattaaatat ttatacgccg cacagaattg aagcgtttga
     6361 taactcaaat atacagggga caaacccggt ttccgcgatg attgtgttta tcgatggcaa
     6421 accatacaaa aaggaatacc gcaaatataa aatcaaaact gttacagggc cggatgatta
     6481 cggttctatg agagaggttg tcagaagacg ctatacgaga gtgcttcgtg agaatctgcc
     6541 gctgcccgat ctgatcatca ttgacggagg aaaagggcag atcaacgcag caagggatgt
     6601 cattgaaaat gaactcggct tggatatccc gatcgccggt ttagcgaaag atgaaaaaca
     6661 cagaacctca aatttactga tcggtgatcc gctggaggtg gtgtatctgg aacgaaacag
     6721 ccaggaattt tacctcctgc agcgcattca ggacgaggtg caccgttttg caatcagttt
     6781 tcacaggcaa atccgcggaa aaagcgcgtt tcaatccgtt ttggacgaca tcccgggtat
     6841 cggagagaaa agaaagaaaa tgctgttaaa gcatttcggt tccgttaaaa aaatgaagga
     6901 agcaagcctt gaggacatca aaaaagccgg tgttcccacg gcggcggctc agctccttta
     6961 cgacaaattg caaaaataat gttgtccttt taaataagat ctgataaaat gtgaactaat
     7021 ttcatagtta gatcgtgtta tatggtgaag atagaggtgc gaacttcaag agtatgcctt
     7081 tggagaaaga tggattctgt gaaaaaggct gaaaggggag cgtcgccgaa gcaaataaaa
     7141 ccccatcggt attatttgct ggccgtgcat tgaataaatg taaggctgtc aagaaatcat
     7201 tttcttggag ggctatctcg ttgttcataa tcatttatga tgattaattg ataagcaatg
     7261 agagtattcc tctcattgct ttttttattg tggacaaagc gctctttctc ctcacccgca
     7321 cgaaccaaaa tgtaaagggt ggtaatacat gggtcttatt gtacaaaaat tcggaggcac
     7381 ttccgtcggc tcagtcgaaa aaattcaaaa tgcggcaaac cgcgcaattg cagaaaaaca
     7441 gaaaggccat caagtcgttg tcgtcgtttc agcaatggga aaatccactg acgaattggt
     7501 cagccttgca aaagctattt ctgaccagcc gagcaaacgc gaaatggata tgctgctggc
     7561 gacaggcgag caggtcacga tttcactcct ttcaatggca ttgcaggaaa aaggctatga
     7621 tgctgtgtct tatactggct ggcaggcggg aatccgtacg gaggccattc acggaaacgc
     7681 cagaattaca gatatcgaca cttcggtttt agcagaccag cttgaaaaag gaaaaattgt
     7741 cattgttgca ggattccaag gcatgacaga ggattgtgaa attacgacat tgggccgggg
     7801 cggttcagat acaacagcag ttgctttggc tgccgcttta aaagctgata aatgtgacat
     7861 atacacagac gtgccaggcg tgtttacaac tgatccgcgc tatgtgaaat cagcgagaaa
     7921 acttgcgggc atctcatacg atgaaatgct tgagcttgcc aatttaggcg ccggcgttct
     7981 tcatccgaga gcagttgagt tcgcgaaaaa tcaccaagtg ccgttagaag tgcgttcaag
     8041 tacagaaacc gaagcgggaa cattaattga ggaggaatca tccatggaac agaatttaat
     8101 tgtcagagga attgcatttg aagatcaaat cacaagagta accatttacg ggctgactag
     8161 cggtctgaca actttgtcta ctatttttac gacacttgcc aaaagaaaca taaacgtgga
     8221 tatcattatc caaacgcagg ccgaggacaa gactggaatt tccttctctg tcaaaacaga
     8281 agatgcagac caaaccgttg cggtgcttga agagtataaa gacgcgctgg aatttgagaa
     8341 aatcgagaca gaaagcaaat tggctaaagt atccattgtt ggatccggca tggtctcaaa
     8401 tcccggtgta gcggctgaaa tgtttgctgt actggcgcaa aaaaacattt taatcaaaat
     8461 ggtcagcaca tctgaaatca aagtgtcaac agtcgtaagc gaaaatgaca tggtgaaagc
     8521 agtcgagtcg cttcacgatg catttgagct ttcaaaacac ccttcagctg tgtaatgaca
     8581 atcaaaaagg cgggactatg cagtcaccgc ctttttgatt acactgggtc tttcatatcc
     8641 catttcacag tcagaaccac tttatcggct ctctttttca cttgttcata tgattcggca
     8701 atctgatcat tcatcaattg aatttgttca gcgataaaac cagcctccag ctgaaagcaa
     8761 ggttctttct gatgtttaag ccggttggaa ataatcggcc cttcaagttc aaattcaagc
     8821 tcctgttttt tagcgcttac gttggtgagg gttccccagc ccgcttcttc aaagaaggcc
     8881 ggaaattcct cccatgattc aagaggaaac ttacgggcga gatgttttcc tgcccaatac
     8941 atcatggaag agtaatcttg gccaagcata tctgggagaa cgatctctcg tattagttcg
     9001 taggcatagg cgttcatttc aatttctttt aggttgtcaa tagattcttc aaatttagac
     9061 ttcatatctg tctcccctct ctcctgcgta tattatagct caaacagggg ggaggattac
     9121 agaatgatcc tgtaattctt atgaaaaatt aagcaagaaa taatatattc ataaaataaa
     9181 atttttcaat caactaatca attcggaaaa ttataattta tgtacgcgtt ttcttgacgc
     9241 ccttttgagg gaggagtaaa atgaaattgt caataaatct taataaagtg cttacaattg
     9301 aaagaagtgg gggaagagat ttagcacatt tcgcacttat caaacagggg gtaaagtaat
     9361 gtctgggaac agagagtttt attttcgaag attgcattcc ttgcttggcg tcataccggt
     9421 cggcatcttt ctcattcagc atttagtcgt caaccagttt gccgcaaggg gcgctgaagc
     9481 attcaatagc gctgctcatt ttatggatag tctgcctttc aggtatgcct tggaaatttt
     9541 tattatcttc ttaccattaa tttatcatgc agtttatggt gtgtacatag cgtttactgc
     9601 gaaaaataac gccggccaat acagctacat gagaaactgg ctattcgtcc tgcagcgtgt
     9661 aaccggtatc atcaccctca ttttcgtcag ctggcatgtg tgggaaaccc gcattgctgc
     9721 acaaatgggc gctgaggtca atttcgacat gatggcgaat attttgagct ctccggctat
     9781 gcttggtttt tacattgtcg gtgttttatc aacaattttc cacttctcga acggtttatg
     9841 gtctttcgct gttacatggg gcatcacggt aacgcctcgt tctcaaagaa tttcgacata
     9901 cgttacgctg attatttttg ttgcactgtc atacgtaggc ttaaaagcga ttttcgcatt
     9961 tgtttaagag tactagatta ctagagggag aggggctatc atgagtcaat caagcattat
    10021 cgtagtcggc gggggtcttg ccggcctcat ggcgacaatt aaagcagcgg aatcaggaat
    10081 ggcggttaag ctgttttcca tcgttcctgt caaacgttct cattcggttt gtgcgcaagg
    10141 cggcataaac ggagcggtca atacaaaagg ggaaggtgac tctccgtggg aacattttga
    10201 tgacacggta tacgggggag actttcttgc caaccagccg ccggtcaagg cgatgtgtga
    10261 agcggcgcct tcgatcatcc acttattaga ccggatgggc gtcatgttta accggacgcc
    10321 tgaaggcctg cttgatttcc gccgattcgg gggtacacag caccacagaa ctgcttatgc
    10381 tggtgcgacg acgggacagc agctgcttta cgcactggac gagcaagtgc gcagatacga
    10441 agttgcgggt ctggtcacaa aatacgaagg ctgggaattc cttggcgctg ttttagatga
    10501 tgacagaacc tgccgcggaa ttgttgcaca aaacctgaca aacatgcaaa ttgaatcctt
    10561 ccgttcagac gctgtcatta tggctacggg aggaccggga atcatctttg gaaaatcaac
    10621 gaactccatg attaatacag gatctgctgc atcaatcgtt tatcagcagg gagcgtatta
    10681 tgcaaacgga gaattcattc aaatccaccc gacagccata ccgggcgatg acaaattaag
    10741 actgatgagt gaatcagcgc gtggtgaagg cggtcgcgtg tggacatata aagacggcaa
    10801 accatggtat ttcctggagg aaaaatatcc ggcatacgga aacctggtgc cgcgtgatat
    10861 tgcgacacgc gaaatatttg atgtgtgtgt gaaccagaag cttggcatta acggtgaaaa
    10921 catggtatat ctcgatctgt ctcataaaga tccgaaagag cttgatatta agcttggagg
    10981 catcattgag atttatgaga aattcatggg agacgacccg cgtaagctcc caatgaaaat
    11041 cttcccggcg gtccattatt ctatgggcgg tttatgggtg gattacgatc aaatgacaaa
    11101 tatccctgga ctgtttgcgg ctggggaatg tgattattct atgcacggtg gcaaccgctt
    11161 gggagcgaac tccctgctgt ctgcgattta cggaggcatg gtggccggtc cgaatgcggt
    11221 gaaatatgta aacggcttag aatcttcagc ggaagacatg tcttcatctt tattcgacgc
    11281 tcacgttaag aaagaagaag aaaaatgggc tgatattatg agtatggacg gaaccgaaaa
    11341 tgcctatgtt cttcacaaag agctcggtga gtggatgacg gcgaacgtaa cggttgtccg
    11401 ccataatgac aagcttttga aaacggatga caaaattcag gagttaatgg agcgcttcaa
    11461 aaagatcaac atcaatgaca cgacaaaatg gagcaaccag ggagcgatgt tcacacgcca
    11521 gttctcaaac atgcttcagc ttgctagggt gattaccctt ggcgcataca accgtaatga
    11581 aagccggggc gcccattata aaccggatta tcctgaacgt aatgatgatg aatggctcaa
    11641 aacaacaatg gctaaacatg taagcccgta tgaagcgccg gaatttgagt atcaggatgt
    11701 cgatgtatca ctgataacgc ctcggaaacg ggattactcg aagaagaagg tggcgaaata
    11761 atcatgagtg aacaaaaaac catacgattt attatcacac gtcaagatac agccgacagc
    11821 acgccttacg atgaagaatt tgagattcca taccgcccga atctgaacgt catttccgct
    11881 ctgatggaaa tccgccggaa tccggttaat gtcaaaggtg agaagacaac ccctgtcaca
    11941 tgggatatga actgtcttga ggaagtatgc ggcgcatgtt caatggtcat aaacggaaaa
    12001 ccccgccagt cttgcacggc gcttatcgac cagcttgaac agccgatccg tttaaaacca
    12061 atgaaaacat tcccagttgt tcgtgatttg caggttgatc gcagcagaat gtttgattca
    12121 ttgaaaaaag taaaagcgtg gataccgatt gacggtacgt acgatttagg accggggccg
    12181 agaatgccgg aaaaacgccg tcaatgggca tatgaattat caaaatgcat gacatgcggc
    12241 gtctgcctcg aagcttgccc gaatgtgaac agcaaatcga agttcatggg gcctgcaccg
    12301 atgtcgcaag tccgcctgtt taacgcgcat ccgacaggct ccatgaataa atctgaacga
    12361 ttagaagcat taatggatga aggcggcctt gcagattgcg gcaactcgca aaactgtgtt
    12421 caatcctgtc cgaaggggat tccgcttacc acttcgattg cagccttgaa tagagataca
    12481 aacttacaag cgttccgcaa tttcttcgga agcgacagag tataagaaga aaaacctctt
    12541 ccgcatggga gaggtttttt taaacaataa ggagatgaaa aaagatgaag cttcccgctt
    12601 atattgatat gccgtttcaa gaatggaaaa catccttttc ttttttcaat aaggtatccg
    12661 taagattttc cgagacagac atgtttgggc atatgaataa tgtaacccct tttatatatt
    12721 ttgaggaggt gcggatttct tattttaaaa agctgaatat gatgagtgaa aacaaacaga
    12781 ccatgacagt cgtggcaagc cagcaatgcg attatttgcg ccaagtcatg ccttatgaag
    12841 agttgcgcat ctatgtgaaa acaagcgcag tcggcagttc atctcttacc ttgcactatc
    12901 tcggagagaa cctcgaaggc gaaccctgct tcaccggggc agtcgtgatg gttcaagtct
    12961 caaaggaaag cggcaaggct gtcagctgga cagatgagga gaaagaaacg ctccttcata
    13021 cacgataaac taattatctt gtaaacgtca cctcctgcgc ccttcttaca tatgatatct
    13081 cgactatatc aaaacccatt cgttgctgat tcgctctcac cttagcaagg agggttacaa
    13141 tacttgaagg agaaagaatt tcaatcgaag ccgctgctaa cgaaaagaga aagagaagtg
    13201 ttcgaattgc tcgttcaaga taagacaaca aaggagattg caagcgagct atttatcagt
    13261 gagaaaaccg ttcgaaacca tatttcaaat ggtatgcata tcgtt
//
