LOCUS       gnlProkkaLHOCDELC_60   14163 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LHOCDELC_60.
ACCESSION   gnlProkkaLHOCDELC_60
VERSION     gnlProkkaLHOCDELC_60
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 18:57:41
            Original ID  :: gnl|Prokka|LHOCDELC_60
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14163
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14163
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2551:4163]"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2552..4163
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     cand_cluster    1..14163
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14163
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="sactipeptide"
                     /region_number="1"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     CDS             complement(142..1812)
                     /locus_tag="ctg60_1"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLETPKDKTHGD
                     YSTNMAMQLARVAKKAPRQIAEEIVAHFDKGKASIEKLDIAGPGFINFYMNNQYLTKLI
                     PSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRF
                     VNEEESERLAFFREYGLKYELEKLRKDLENFRVPFDVWYSETSLYQNGKIDKALEALRE
                     KGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWG
                     ADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKP
                     AADLDFSHIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     CDS             complement(1809..2237)
                     /locus_tag="ctg60_2"
                     /transl_table=11
                     /translation="MKQETPITLHVKSVIEDDGNQEVIEFRTTGFYYVKQNKVYLSYYE
                     EHDLGKVKTIVKVSEGEVLVMRSGAVKMNQRFVKGASTIAKYKMSFGELELKTSTKSIQ
                     SDLDEEKGRISIAYDMHVGDEQEHLHNMTITYEGGTHA"
     CDS             2552..2683
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_functions="biosynthetic-additional (sactipeptides)
                     predicted sactipeptide"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg60_3"
                     /sec_met_domain="Subtilosin_A (E-value: 9.6e-31, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       2552..2581
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="ctg60_3_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       2582..2683
                     /prepeptide="core"
                     /locus_tag="ctg60_3_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="33.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[2551:2581](+)"
     CDS             2817..4163
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg60_4"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1081.4, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 5.4e-31,
                     bitscore: 98.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.5e-09, bitscore: 28.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.1e-23, bitscore: 75.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 5.5e-12, bitscore:
                     37.5, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.7e-11, bitscore: 36.0,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIEQMFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLN
                     KTAYELCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQLGNRAIR
                     HTITTSGSNEFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSIEQFKKTADMLFDN
                     GVLTCEITGGEIFVHPNANEILDYVCKKFKKVAVLTNGTLMRKESLELLKTYKQKIIVG
                     ISLDSVNSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKV
                     RDLGAKAFSYNWVDDFGRGRDIIHPTKDAEQHRKFMEYEQNVIDEFKDLIPIIPYERKR
                     AANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFNSPLVHKLWQAQAPRF
                     SEHCMKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     CDS             4176..4337
                     /locus_tag="ctg60_5"
                     /transl_table=11
                     /translation="MSPAQRRILLYILSFIFVIGAVVYFVKSDYLFTLIFIAIAILFGM
                     RARKADSR"
     CDS             4334..5053
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 125.6; E-value:
                     4.3e-38)"
                     /gene_kind="transport"
                     /locus_tag="ctg60_6"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYERDNVILEQVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGRFTLCGIEAEAGMPQKTSDQQKTHRYFAADYPLLFTEITAKDYVS
                     FVHSLYQKDFSEQQFASLAEAFHFSKYINRRISELSLGNRQKVVLMTGLLLRAPLFILD
                     EPLVGLDVESIEVFYQKTREYCEAGGTILFSSHLLDVVQRFCDYAAILHNKQIQKVIPI
                     GEETDLRREFFEVIGHE"
     CDS             5046..6356
                     /locus_tag="ctg60_7"
                     /transl_table=11
                     /translation="MNNIIPIMSLLFKQLYSRQGKKDAIRIAAGLVILAVFEIGLIRQA
                     GIDESVLRKTYIILALLLMNAYMVFLSVTSQWKESYMKLSCLLPISSRSFWLAQSVVLF
                     VDTCLRRTLFFFILPLFLFGNGTLSGAQTLFWLGRFSFFTVYSIIFGVVLSNHFVKKKN
                     LMFLLHAAIFACVCLSAALMPAATLPLCAVHMLWAVVIDFPVFLQAPPQQSRMHSFMRR
                     SEFSFYKREWNRFISSKAMLLNYAVMAAFSGFFSFQMMNTGIFNQQVIYIVISALLLIC
                     SPIALLYSIEKNDRMLLITLPIKGKTMFWAKYRFYSGLLAGEFLLVVMIVGFISGRPIS
                     VLTFLQCIELLLAGAFIRLTADEKRPFFSWQTEQQLWSGFSKYRSYLFCLPLFLATLAG
                     TAVSLAVIPIAGLVIVYYLQKQDGGFFDTSKRERLGS"
     CDS             6322..7506
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg60_8"
                     /sec_met_domain="Peptidase_M16_C (E-value: 5.7e-07,
                     bitscore: 21.2, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQAKENGLEVNLLKTHQFSTISIAASFLKPIESAAEPEEETIYF
                     YGAAAYLKEQIIDDFGCAAGSRFMYSANLFFDQQLKTCGTRLIHPLYNGNLHVDALMKT
                     FADLSFPSSLSFEAVEKARNELLLKIEKKFTDPFSYSAARLAEEVFGNPMYGTGMFGRK
                     DRIKAIHPKRFHDATDFIVDLVSQQKQLNILGQVQACDVRGHAPQTSAVTSERIPVNRH
                     VFETETRSAAGPSVLTLGFDCGEMKDASDYIKIQLIDGLLGKYGHSALFKHFREKDLAV
                     YHVITRYDVMNNLLLVSICTDQLHEIDIPPRVLEAVSAFHTDERELEQAKQFLRNELLL
                     QFDSPEGLLAYMGILRRFSCTKEALLDGISAVTCRDVLQFIATINYIGAHVVRG"
     CDS             7511..8791
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg60_9"
                     /sec_met_domain="Peptidase_M16 (E-value: 2.7e-15, bitscore:
                     48.2, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKAFFQQLDERTDIRYTDSGLKIFRLKFPRAHLRLCNVKIDFG
                     SRDVCIRAESGDTLLPYGTAHFLEHLLFWHNGRNLYSDFFAHGALLNAFTTYTDTNFMF
                     TSLPDRLRQTIPILLDALWNHSFDKKIVAQEKAVITSEIQTAHLNHQLSYHYQLISMLS
                     PSSPAAVFPAGRIEDIEALDISDLQKAYKAAYQTHRMTLFLIGGSENTETLLPPHLQLE
                     KRPDYHAERKIIPACPPALSQKMMLGDEERMEDTWTGLQIGALPGQNDLLTIKLYWDIA
                     ARILFQLDSPFFQEIQQTYRLEIDRLSAETYIYEDGGFLILHSQGTHSSAYIDVASYYV
                     TQKKEQAAAWLQYGKDSLTDAIIYDSDYVRKCFEWAAECDRCDCSFLDMYHIIQDMDAQ
                     VFLSLIDAMASSNKAIIHVSQKEAIRQ"
     CDS             8788..9489
                     /locus_tag="ctg60_10"
                     /transl_table=11
                     /translation="MKKNTVFTLLLLLIGMAAYSFGWVQAVAEAAAHYIQMINNDAVRL
                     GLLACTAALLMLPAFLYLHYVTQSVKNMTAAFQKLTQSHQSCCDFQQHNLCSRYAEDVK
                     SLRDGYKNVRQTYVMAAVLCQVIIFGCMFEIVKAVPFRLHTPPALSMGLAMLLILYLLF
                     CMRTYLRQLFRHGSLFRKVFAGVLAAAGIWWMLSFTISELLFLIILAAIQQIRSFIYKR
                     FSYRSTASLDL"
     CDS             complement(9495..10871)
                     /locus_tag="ctg60_11"
                     /transl_table=11
                     /translation="MKKNDLSALQENCFCFCDEEISREAPFQVPIDIPKGFKVDSAEAS
                     AAVTWSTDNLSCVSEPCLIQTGPETEDIGVRYAVRVQGTIMLLVSVSPVRNQYGQGDGA
                     VSVIHTEEIDQVVYYAAQSDRCPDFSQMTVEDLLIVPPFYGSPLTVAGTLVLPPSPDPQ
                     SYVFTANTGDSTVSVIDADLNTVVKTILFSAVPTNLGVTFDKAFTYVLHGNTNLVSVID
                     NKTLTIINTITVGGGPRKIEFDPTDEYAYVMAAGSIYMIDTANQSVIDVIAIPGALDFA
                     LDPNGQYVYTANGSSWSVDKYDVNTGQLVESIIDSFEFPSLIATPYAGNFAYVLNGELW
                     PKGVTEISLSPLSRGGDFNRLFETLRTIVFSLDSTRAYFLEPYSEPFLINNLYVVNTAR
                     QRIIANVPLPGAFDPAVTPDKQYIYAAQPNDNAVTVYRTSDYTAVKVIPVGAGPSAIVM
                     "
     CDS             complement(10910..11395)
                     /locus_tag="ctg60_12"
                     /transl_table=11
                     /translation="MFAYVLNFGLVQKVDLSTGEVTGTIERELIVSSIETDSPERYAYV
                     LEQEFLFNYLTVIDLNTFTISNTQELEPDGQYRMFTSGTGVYLYDDFTGNLYSVSPNGA
                     GVIGNLPQSATDYAFTPNGDFLYATRFIEQSIIVYNTDDYSEETVISLGVSPGAITI"
     CDS             complement(11428..12261)
                     /locus_tag="ctg60_13"
                     /transl_table=11
                     /translation="MRKNKLSFKEKAGAEQEECLCFCEGEASREAMFQAPIELPEGFVV
                     DPAEAVANVTWNADSLSCVSDRCLIQTGPEPDEVGVQFAVRLQGTVTLLVSVSPVRNQY
                     GQGDGAVSVIHNAEIDQVVYYSDEPDDCPDISNITIENLVVVPPFYGSPLSVTGTIVLV
                     PEPEPVYAFTANPNDQSVSVIDTNTHTVVTTIALPYNPAGIEITPDKSAVFVLHPNNNV
                     ISVIDYDTLTVTATILLDQPPRLIRFIPNHEFAYVFTGTAIYVIGIDTLTVERSI"
     CDS             12617..13636
                     /locus_tag="ctg60_14"
                     /transl_table=11
                     /translation="MEEDQDLHLYYSLMEFRHNLMLEYLEPLEKMRIEEQPRLSDLLLE
                     IDKKQARLTGLLEYYFNFFRGMYELDQREYLSAIKFFKKAESKLIFVKDRIEKAEFFFK
                     MSESYYYMKQTYFSMDYARQAYEIYKENEAYNIRLLQCHSLFATNFLDLKQYEDAVSHF
                     QKAYSMAEAEKQPQLMGRTLYNIGLCKNSQSQYEDAITYFKRAIAVFEESNILPSLPQA
                     YFLITQIHYKLGKMDKAHEYHSKGMAYSQKAGDVIYLSEFEFLKSLYLSGPDEEAIQGF
                     FDFLESKMLYADLEDFTIDVAKYYHERKNFQKASAYFLKVEQVRQLIQGGVSLYEIEV"
     CDS             13620..13739
                     /locus_tag="ctg60_15"
                     /transl_table=11
                     /translation="MKLKSKLLLSCLALSTVFVATTIANAPTHQIEVAQRGMI"
     CDS             13837..14148
                     /locus_tag="ctg60_16"
                     /transl_table=11
                     /translation="MSLKSVRTHFTQWNRENDVTEFETSSATVEQAAETIGVSLSRIAK
                     SLSFRGEGDQVILIVAAGDAKIDNKKSRQTFGFKARMLSPNEVLEQTGHEIGGVCPIG"
ORIGIN
        1 gcatgtggga gcgctttttc tgcatctgaa acctgatgaa tatctaaaga aactgtataa
       61 aacaaaaaag cttgtagaaa aaacgtcgtt ttctctacaa gctaaggaca aagcccgaag
      121 actttgtcct tttgatcgtg attacatttt ttccggagcc gatacgccga tcagctgaag
      181 cgcattgttc agcgtaattt gcgttgcctt cattaaagcc aggcgcgcac ggcttttctc
      241 ttcattttca gggtcgatga ctttctctgc gttgtagaag ctgtgcagag cagaggccag
      301 atcataaata tagtttgtga cacggtgcgg aattcgtttt tccgctgctt ccgccactgc
      361 ctctgggaag ccgccgatcg ttttcagcag atcgtattct ttttctgatt gaatatggct
      421 gaaatcaaga tccgccgccg gtttaagtcc ctgctcttcc ccttggcgaa gcatgctgca
      481 gattcgggca tgtgcatatt gtgcataata cacagggttt tcgttagatg ttgatacagc
      541 aagatctaag tcaaaatcca tatgggtgtc cgcacttcgc atcgcaaaga agtaacgaac
      601 ggcatccaag ccgacttctt caatcaggtc acgcatcgtt acggctttac cggtccgttt
      661 gctcattttc attttctcgc cgtttttgta aaggtgaacg agctgaatga tttctacttc
      721 aagcgttcct ttttcatagc ccagcgcttc gattgccgct ttcatacgcg ggatgtagcc
      781 gtggtgatcg gcgccccaaa cgttgatcag cttatcaaag ccgcggtcaa gcttgtcctt
      841 atgatacgcg atatcaggaa gcaggtacgt gtacgtgccg tccttcttga tcaatacgcg
      901 gtctttatca tcgccaaacg tcgtggaacg gaaccaagtc gcgccgtctt cttcatagac
      961 atggcctttt tcgcggagcg cttcaagcgc cttgtcgatt tttccatttt ggtacagtga
     1021 agtttctgaa taccacacat caaacggcac acggaagttt tccaagtcct tgcgaagctt
     1081 ttccagctca tatttcaggc cgtattcacg gaaaaacgcg aggcgttcac tttcttcttc
     1141 gttaacgaaa cgatcaccgt attcctcagc gagacgcttt ccgatcgcaa tgatatcctc
     1201 gccgcggtag ccatcctccg gcatcggttt ttccaatccg agtgcttcaa agtaacggac
     1261 ttcaacagaa agcgccagat tgttgatttg gttacccgca tcgttaatgt agtattcgcg
     1321 gcttacatcg taacccgctt ttgaaagcac gttgcacaag gaatcgccga cagccgcccc
     1381 gcgcgcatgc ccgaggtgaa ggtctcccgt cggattcgct gatacgaatt ctacctgaac
     1441 tcgttcaccg tttccgatgt tcgtttcccc gtatgcttcc cctgcttcca gtacagacgg
     1501 aatcagcttt gttaaatatt gattgttcat atagaaattg ataaaacccg ggccggcgat
     1561 atccagtttt tcaatcgaag cctttccttt atcaaaatgg gcgacaatct cttcagcgat
     1621 ttggcgcggc gctttttttg ccactcttgc cagctgcatc gccatattcg ttgagtagtc
     1681 gccgtgtgtt ttatctttcg gtgtttctaa aacaacattg ggaatctggc tttcttcagc
     1741 cagtcccgct ttcagaacgg ccgctttgat ttcttctttc agcacgtcct tcatttgttc
     1801 cgcaatgttc atgcgtgagt tcctccctca tacgtgatcg tcatattatg taaatgctcc
     1861 tgctcgtctc cgacatgcat gtcatatgcg atgctgatac ggcctttttc ttcatcgaga
     1921 tcagattgaa tcgattttgt gcttgttttc agctcaagct caccaaatga cattttatat
     1981 ttagcaattg tggaagctcc ctttacgaaa cgctgattca ttttgacagc gcctgacctc
     2041 atgaccagga cttcgccttc gcttactttc acaatcgttt tgactttgcc taagtcgtgt
     2101 tcttcataat aagatagata cactttattt tgttttacat agtaaaatcc ggtggtgcgg
     2161 aattcgatga cttcttggtt tccgtcatcc tcgatcacag acttcacatg gagtgttatc
     2221 ggtgtctctt gcttcattct gacacgtcct tttcatcatt ccactttgac ttgaatagta
     2281 taatcattcg gtttgtaaac ttcaactgct tctatcttac catcattgct catcagattt
     2341 gaagataaac ctcataaaaa gcatttcctt atatagaaga gaaaatcata tcactaatta
     2401 cctttagtaa atgttacatt tttccgaaat ctatcatttc cttttcacat ttttttcaaa
     2461 atatatgtat tgaattagta atttgatagt tttaagataa aagtacaaca tagatctgtt
     2521 agaaaaacaa aaaaaaaggg aggattcaat tatgaaaaaa gctgtcattg tagaaaacaa
     2581 aggttgtgca acatgctcga tcggagccgc ttgtctagtg gacggtccta tccctgattt
     2641 tgaaattgcc ggtgcaacag gtctattcgg tctatggggg taaggatctc ccaaaagggc
     2701 atagtcattc tactatgccc tttttaagta aattacaatt tttaactaaa atctacctct
     2761 tggatataca tacacaaccg tttttcattt gaatcatatg tataggggat ggtattttgt
     2821 ttatagagca gatgtttcca tttattaatg aaagtgtaag agttcaccag cttcctgagg
     2881 gcggcgtgtt agaaatcgac tacttgcgcg ataatgtctc catttctgac tttgagtatt
     2941 tggatctcaa caaaacagct tacgagctct gcatgcgcat ggatggccaa aaaacagctg
     3001 agcagatttt agctgagcaa tgtgcagtgt atgatgaatc accggaagac cataaagatt
     3061 ggtattacga catgctcaac atgctccaga acaagcaggt tatccagctt ggaaaccggg
     3121 ccatccgcca taccatcacc acgagcggaa gcaatgaatt tccgatgccc ctgcacgcca
     3181 cctttgaact gacgcaccgc tgtaatttga aatgcgccca ctgttatttg gaaagctcgc
     3241 ctgaagcgct cggcaccgtg tcgattgagc aattcaaaaa aacggctgat atgctgtttg
     3301 ataacggtgt attgacatgc gaaatcacag gcggagaaat ttttgtccat ccaaacgcca
     3361 atgagattct tgactatgtg tgtaaaaagt tcaaaaaagt cgctgtctta acaaacggaa
     3421 cactcatgcg aaaagagagc ctggagcttt tgaagactta caagcaaaaa atcatcgtcg
     3481 gcatttctct tgatagtgtc aattccgagg tccatgactc ctttagaggg agaaaaggct
     3541 cttttgccca aacttgtaaa acgataaaat tgttgagtga ccacggtata tttgtcagag
     3601 tcgccatgtc tgtcttcgaa aaaaacatgt gggaaatcca cgatatggcc caaaaggttc
     3661 gggatctcgg agcgaaggcg ttttcttaca attgggttga cgatttcgga agaggcaggg
     3721 atattatcca tccaacgaaa gacgccgagc agcaccgcaa gtttatggaa tacgagcaaa
     3781 atgtgattga tgagtttaaa gatctgattc cgattattcc ctatgagaga aaacgcgcgg
     3841 caaattgcgg cgctggctgg aagtccattg tgatcagccc gttcggcgaa gtacgtcctt
     3901 gcgccctctt tccaaaggaa ttttcattgg gaaatatttt tcatgattcc tatgaaagca
     3961 tctttaactc ccctctcgtc cataaactgt ggcaagcgca ggcgccgcgg ttcagcgaac
     4021 attgcatgaa agacaaatgc ccgttcagcg gctattgcgg aggctgttac ttaaaagggc
     4081 tgaactctaa caaatatcac cgaaaaaaca tttgctcttg ggcgaaaaat gaacaattag
     4141 aagacgtggt ccagcttatt taggagggaa acgatttgtc accagcacaa agaagaattt
     4201 tactgtatat cctttcattt atctttgtca tcggcgcagt cgtctatttt gtcaaaagcg
     4261 attatctgtt tacgctgatt ttcattgcca ttgccattct gttcggaatg cgcgcgcgga
     4321 aggctgactc gcgatgagca ttttggatat acacgatgta tccgtttggt atgaacggga
     4381 caacgtcatc ttagaacaag tggatttaca tttagaaaaa ggcgccgttt acgggctgct
     4441 tggggtaaac ggcgccggaa aaacgacact gattaatacg ctgacaggcg tgaaccgcaa
     4501 tttcagcggg cgctttacac tgtgcggaat tgaagcggag gccggcatgc cgcagaaaac
     4561 atcagatcag cagaagactc accgttactt cgccgccgat tatccgctgc tatttacaga
     4621 aattacggcg aaggactatg tgtctttcgt ccattcgctt tatcaaaagg atttttcaga
     4681 gcagcagttt gccagtttgg ccgaggcctt tcatttttcg aaatacatca acaggagaat
     4741 ttcggagctg tccttgggga acaggcaaaa ggttgtattg atgacaggct tattgctgcg
     4801 cgctccccta tttattttgg atgagccgct cgtcggtttg gatgtggaat cgatagaggt
     4861 tttttatcag aaaacgcgcg agtactgtga agcaggcggg accattttgt tttcttctca
     4921 tctgctcgat gtcgtgcaaa gattttgtga ttacgcggcc attcttcaca acaaacagat
     4981 ccaaaaggtc attccgattg gagaggagac cgatctgcgg cgggaatttt tcgaggtgat
     5041 cggccatgaa taacataatc cccatcatgt ctttgctgtt caaacagctt tacagccggc
     5101 aagggaaaaa ggacgccatc cgcattgccg caggccttgt cattctggcc gtatttgaaa
     5161 tcgggctgat ccgccaggcc ggcattgatg aatcggtgtt gcgcaaaacg tatatcatac
     5221 tcgcgcttct cttaatgaac gcatatatgg tgtttctttc tgtgacatct caatggaagg
     5281 aatcttatat gaaactgagc tgcctgctgc cgatttcttc acggagcttt tggctcgccc
     5341 agagtgtcgt tttgtttgtc gatacctgtt tgagaagaac gttattcttt tttattttac
     5401 cgctgttctt atttggaaac ggaacgctgt caggggcgca aacattgttt tggctcggca
     5461 ggttttcgtt ttttaccgtt tactccatta ttttcggagt tgtgctaagc aaccacttcg
     5521 tcaaaaagaa gaacttgatg tttctgctgc atgcggcgat attcgcctgt gtatgtctca
     5581 gcgccgcttt gatgccggcc gccacgcttc cgctttgcgc ggtgcatatg ctgtgggcgg
     5641 tggtcattga ctttcctgtc tttctgcagg cgcctccgca gcagagcagg atgcattcat
     5701 ttatgcggcg atctgagttt tcgttttaca aaagagaatg gaaccgattt atctcttcta
     5761 aagcgatgct gttaaattac gcggtaatgg cggcgttcag cggcttcttt tcgttccaga
     5821 tgatgaatac cggcatcttc aatcagcaag tgatttatat cgtgatttcc gcgcttctgc
     5881 tcatctgctc gccgatcgcc cttttgtact cgattgaaaa aaatgaccgg atgctgctca
     5941 tcacgcttcc gatcaagggg aaaacgatgt tttgggcgaa atatcgcttt tattcaggcc
     6001 tattggcagg cgaatttctc cttgtcgtga tgattgtggg tttcatcagc ggccgtccga
     6061 tttcagttct cacttttttg cagtgcattg agttgctgct ggcgggagct tttatcaggt
     6121 taactgcgga tgaaaaaagg cccttcttca gctggcagac ggagcagcag ctatggagcg
     6181 gtttctcaaa atatcggtct tatctgtttt gtcttcccct attcttagcc acattagccg
     6241 gcaccgctgt atccttggcg gtcattccga tagccggtct ggtcatagtc tattacctgc
     6301 aaaaacagga tggtggtttc tttgatacaa gcaaaagaga acggcttgga agttaacctg
     6361 ctgaagactc atcaattttc aactatatca atcgccgcga gctttctgaa accgatcgaa
     6421 agcgcggcgg aacctgagga agaaacgatt tatttttacg gcgccgccgc atacctgaag
     6481 gagcaaatca ttgacgattt cggttgtgct gccggcagcc gtttcatgta ctcagcgaat
     6541 ctcttttttg atcagcagct gaaaacctgc gggacccgtt tgattcaccc attatataat
     6601 gggaatcttc atgttgacgc cctgatgaaa acttttgcag acttgtcttt cccttcttct
     6661 ctttcattcg aagcagttga aaaggccagg aatgagctgc tgctgaaaat cgaaaagaaa
     6721 ttcactgatc ccttctccta ctcggcggcg cgcttggctg aggaggtctt cggaaacccg
     6781 atgtacggca caggcatgtt tggccggaaa gacaggataa aggcgattca tcctaaacgg
     6841 tttcacgacg caacggactt tatcgttgat ttagtgtccc agcaaaaaca gctgaacata
     6901 ttgggacaag tacaagcatg tgatgttcgg ggacatgccc cgcaaacgtc cgctgtaacg
     6961 tccgaaagaa tacccgtaaa ccggcatgtt tttgaaacag agacacgcag cgctgcaggt
     7021 ccttccgtct tgacactcgg atttgactgc ggagagatga aagatgccag cgattatatc
     7081 aaaatacagc taatagacgg attactggga aagtacggcc attccgcttt attcaagcac
     7141 ttcagagaga aagatctggc agtctatcac gttatcaccc gttacgatgt catgaacaat
     7201 ttgctgcttg tttcaatatg tacagatcag cttcatgaga tagacattcc cccgcgcgtt
     7261 ttggaagctg tctcagcttt tcatacagat gagcgggaac tagaacaggc aaagcagttt
     7321 ttacgcaatg aattgctgct gcaattcgat tctcccgaag gtctattggc ctatatgggg
     7381 atcctgcgcc gcttctcctg cacgaaagaa gccttgctgg atggcatctc agcggttaca
     7441 tgccgtgatg tattgcaatt catagcgacc atcaattata tcggagctca tgtagtaagg
     7501 ggatgaaaag atggaaaaga aagccttttt tcaacagctg gatgaacgaa ccgatatcag
     7561 atacacagac agcggactaa aaatattcag attgaaattc ccccgcgccc acctgcggct
     7621 gtgcaatgta aaaatcgatt ttggaagccg ggatgtatgt atacgggcag aatccggtga
     7681 tacactgctt ccgtatggca cagcgcattt tttagagcat cttctcttct ggcataacgg
     7741 ccgcaatctg tacagtgatt tttttgcgca tggcgcgctt ttaaacgcat tcactaccta
     7801 caccgatacc aatttcatgt ttacctcatt accggatcgg ctcagacaaa cgatccccat
     7861 cctgcttgat gctttatgga accactcatt tgacaagaag attgtcgctc aggaaaaagc
     7921 tgtgattaca agcgaaattc aaacagcaca ccttaaccat cagctctcat atcattatca
     7981 gctgatcagc atgctttctc cctcctcacc agctgccgtt ttccccgcag gcagaatcga
     8041 agatattgag gcgcttgaca tcagtgattt acaaaaagcc tataaggctg cctaccaaac
     8101 ccatcggatg acgctgtttt tgattggggg ctcagaaaat acagaaacgc tattgcctcc
     8161 tcacctccag ctggaaaagc gtccggatta tcatgctgaa agaaaaatca tcccggcatg
     8221 ccctccagcc ctctcacaaa aaatgatgct gggtgatgag gagcggatgg aagatacatg
     8281 gaccggatta cagatcggcg cacttcccgg gcaaaacgat ctgttgacga tcaaacttta
     8341 ttgggatatc gcggctcgta ttctatttca attagattca ccgttttttc aagagattca
     8401 gcaaacgtac cgcctggaaa tcgatcgttt gtcagccgag acttatatct atgaggatgg
     8461 cggtttcttg atccttcaca gtcaagggac ccattcttca gcttatatcg atgtggcttc
     8521 atactatgtc acacagaaga aagaacaggc tgccgcctgg cttcaatacg gcaaggactc
     8581 tttgacagac gcgatcattt atgacagcga ttatgtgcgt aaatgcttcg agtgggcagc
     8641 cgagtgtgac aggtgcgatt gctcgtttct tgacatgtac cacatcattc aagatatgga
     8701 tgcgcaggtt ttcttgtctc tcattgatgc aatggcatct tctaacaaag cgatcattca
     8761 cgtttctcag aaagaggcga tcagacaatg aaaaaaaaca ctgtctttac ccttttattg
     8821 ctgcttatag gtatggcggc ttattccttc ggctgggttc aggccgttgc cgaagccgcc
     8881 gcccactata tacagatgat caacaatgat gctgtacggc tcggactgct ggcttgtacc
     8941 gctgccctcc tgatgctgcc tgcttttctc tatcttcact atgtcaccca atctgtgaaa
     9001 aacatgacag cagcttttca gaaactcaca cagtctcatc aaagctgctg tgactttcag
     9061 caacacaact tgtgcagccg atatgcagaa gacgtcaaat cgctgcgtga cggctataaa
     9121 aacgtccgcc aaacatacgt gatggctgcc gtgttgtgcc aagtcatcat attcggctgc
     9181 atgttcgaaa tcgttaaagc cgtccctttc cgccttcaca cgccccctgc cctttcaatg
     9241 ggacttgcga tgctactgat cctgtattta ttgttttgca tgcgaacgta tttgcggcag
     9301 cttttccggc acggcagcct gttcagaaaa gtgtttgcgg gagtgctggc agcagccggg
     9361 atttggtgga tgctcagttt cactataagt gaactgctgt ttctgattat cctggctgcc
     9421 atccagcaaa tcagatcatt tatttataag cgattctctt atcgcagcac cgcttctctt
     9481 gatctataaa atagctacat cacaatcgca gacgggcccg cgccaaccgg aatcaccttc
     9541 acggctgtat aatcacttgt gcggtacaca gtcacagcat tgtcgttggg ctgtgccgca
     9601 taaatatact gtttgtccgg cgttacggcg gggtcaaaag cgccggggag aggcacgttt
     9661 gcaatgatcc tctgtctggc cgtattaact acgtataagt tattaatgag aaacggttca
     9721 ctatatggct ctagaaaata agctctagta ctatcgagag aaaatacaat cgtcctcagc
     9781 gtttcaaata aacggttaaa gtcccctccc ctgcttaatg gtgacaaact aatctccgtt
     9841 acacctttcg gccacagctc accattcaac acgtacgcaa aatttccagc gtaaggagtt
     9901 gcaattaaac tgggaaattc aaatgaatct atgatacttt ctaccaactg cccagtattt
     9961 acatcatatt tatcaaccga ccaactgctt ccattagcgg tatagacata ctgtccattc
    10021 ggatcaagag caaagtctaa agcgccgggt atcgcgatta catcaattac tgattgattg
    10081 gccgtgtcaa tcatatatat agatccggcg gccatcacgt aggcgtactc atctgttgga
    10141 tcaaattcga tctttctcgg tcctcctcca acagtaatgg tatttatgat ggttaatgtt
    10201 ttattatcaa tcactgagac aaggttggta ttcccatgga ggacatacgt gaatgcttta
    10261 tcgaaagtaa cgcctagatt agttggcaca gcagaaaaca ggattgtttt tacaacagtg
    10321 tttaaatctg catcaatgac cgaaaccgtg ctgtctccag tattggcagt aaacacatac
    10381 gattgagggt ctggcgatgg cggcaaaaca agtgtcccgg ccaccgtgag cggactgccg
    10441 tagaaaggcg gcacgatgag aagatcttcc actgtcatct gactaaaatc aggacagcgg
    10501 tcagactgtg ctgcataata aacaacttga tcaatctctt cagtatgaat cacagaaacc
    10561 gccccgtctc cttgtccata ttgatttcgc acaggcgaca cactgacaag aagcataatg
    10621 gtcccttgta ctctcacagc atatcgaaca ccaatatctt ctgtttccgg cccagtctgg
    10681 attaagcaag gctcactgac acaggacaaa ttgtctgtac tccatgtaac agccgctgac
    10741 gcttcggctg aatcaacctt gaagccctta gggatatcta ttggcacttg aaacggcgct
    10801 tcccggctaa tttcctcatc acaaaaacag aaacaatttt cctgtaaagc agaaagatca
    10861 ttctttttca tgaattcacg tccttttaaa aatgcacaac atgcagcggt taaatcgtaa
    10921 tggcacccgg tgaaacccca agagatatca cagtttcctc agaataatca tctgtgttgt
    10981 aaacaatgat gctctgctct ataaaacgag ttgcatacag aaaatcgcca ttcggggtaa
    11041 acgcatagtc tgttgctgat tgcggaagat ttccaattac acctgctcca ttcggactga
    11101 cagaatataa attgccggta aagtcgtcat ataaatacac acctgttccg ctcgtaaaca
    11161 ttctatattg gccgtcaggc tccagttctt gggtattgct gatcgtaaac gtatttaagt
    11221 caataaccgt caaataattg aataagaatt cttgttctaa gacatacgca taccgctccg
    11281 gagaatctgt ttctatggat gatacgataa gctctcgttc aatcgttcct gtgacttcac
    11341 cggtggataa gtccactttt tgcactaacc caaaattaag aacataggcg aacaacccat
    11401 tggggtcaat tgcaatatca aaaccttcta tatagacctc tcaacagtca acgtatcaat
    11461 tccaatcaca taaatggcag taccggtgaa aacataagca aactcatgat tagggataaa
    11521 tctaatcaat cgaggcggct gatccagcaa tatagttgct gtcactgtta atgtgtcata
    11581 atcgatgaca gaaatcacat tattgttggg atgtaagaca aacacagcgc ttttatctgg
    11641 cgtaatttca atacctgccg gattgtacgg aagagcaatc gttgtcacaa cagtatgggt
    11701 gtttgtatca atcacagaaa ctgattgatc atttggattc gctgtaaacg cgtagacggg
    11761 ttccggctcc ggtacaagca caatcgtccc cgtcaccgat aaaggactgc cgtaaaacgg
    11821 cggaacaaca acaaggttct caatcgtgat gttactgata tccgggcaat catccggttc
    11881 atcggaataa tagacgactt gatcgatttc tgcattgtga atgacggaaa cagccccatc
    11941 cccttgtcca tattgatttc gcacaggtga gacactgacg agcagcgtaa cggttccctg
    12001 cagacgcact gcaaattgaa caccgacctc atcaggctct ggccccgttt gaattaagca
    12061 acggtcactg acacaagaaa ggctgtctgc attccacgtc acgtttgcaa cagcttcagc
    12121 cggatcaacg acaaatcctt caggtaattc aatcggcgct tgaaacatgg cttctcggct
    12181 tgcttctccc tcacaaaaac ataagcactc ttcttgttct gctcctgctt tttctttaaa
    12241 ggaaagcttg ttttttctca ttccttcact tccttttcag acatacactg ctcacgcaga
    12301 tataacagaa tatggaagag taacgtgttt gcttgtacaa attactgagg gtaaaagctt
    12361 ctttttgaaa atatatctcc aaacatgcgg tgtaacgaaa gaaaaaattg cggttttttt
    12421 gcgcttctca caagaatgtt gatgataaaa tatgacatat atagaattat gaagggaggg
    12481 atttgcaaac gtgacaggtg tcatatcttc ttcttccatc ggagaaaaga ttaacgaatg
    12541 gtatatgtac atacgccgat tcagcatacc cgatgcagaa tatttgcgac gagaaatcaa
    12601 gcaagagctg gatcaaatgg aagaagatca agaccttcat ttgtactatt cactgatgga
    12661 gtttcggcac aacctgatgc ttgagtacct tgaaccgtta gaaaaaatga ggattgagga
    12721 acagccgaga ctgtctgatc tgctgcttga gattgataaa aaacaggctc gtttaacagg
    12781 tctgcttgag tactatttta atttcttcag aggcatgtat gagctggatc agcgggaata
    12841 tctgtcggct attaaatttt tcaaaaaggc cgaaagcaag ctgatattcg ttaaggatcg
    12901 gatagagaaa gctgagtttt tctttaagat gtctgaatct tattactata tgaaacaaac
    12961 gtatttttca atggactatg cacggcaagc atatgaaata tacaaagaaa atgaagctta
    13021 taatataaga ttgctgcagt gtcattcttt atttgccacc aattttttag atttaaaaca
    13081 gtatgaggat gccgtctcac attttcaaaa agcttattct atggcagaag ctgaaaagca
    13141 gccccaatta atgggaagaa ctttgtacaa tatcgggctt tgtaaaaaca gccaaagcca
    13201 atatgaggat gccataacat atttcaaaag agcaatagct gtttttgaag aatcaaatat
    13261 tcttccttcc ttacctcaag cgtatttttt aattacacag atccattata aattaggaaa
    13321 aatggataaa gctcatgaat atcatagtaa gggaatggct tattcacaaa aggccggaga
    13381 tgtaatatat ttatcagagt ttgaattttt gaaatcttta tacttatcag gcccggatga
    13441 agaagcaatt caaggatttt ttgattttct cgaaagtaaa atgttgtatg ctgatcttga
    13501 agatttcact attgatgtgg caaaatatta tcatgaacgt aaaaattttc aaaaagcttc
    13561 tgcttatttt ttgaaggtgg aacaagtaag gcaacttatt caaggaggag tgagtttgta
    13621 tgaaattgaa gtctaaacta ttactctctt gtctggctct aagcactgtg ttcgtggcaa
    13681 caactattgc aaatgcacct acacaccaaa ttgaagttgc acaacgagga atgatttaac
    13741 cgccgtccat cggcggtttt tttgtcccct ctttacccag tctcccaatc cattctatga
    13801 ttttttcaat aatcttaaaa atagtggaaa tgcagcatgt ctctaaaaag tgtgagaacc
    13861 cactttactc aatggaatcg agaaaatgat gtgacggagt tcgaaacgtc gagtgcgaca
    13921 gttgaacagg cagctgagac aatcggcgta agcctgtcta gaatcgccaa gtccctgtcc
    13981 ttcagagggg aaggagatca ggtgattctg attgtggcag ccggcgatgc caagatcgac
    14041 aacaaaaagt ccaggcaaac atttggcttt aaagcaagaa tgctctctcc taatgaggta
    14101 ctggagcaga caggccatga aattggagga gtttgcccaa ttggatagac tcatgatcct
    14161 gag
//
