LOCUS       gnlProkkaIPFFCMEA_93   14080 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IPFFCMEA_93.
ACCESSION   gnlProkkaIPFFCMEA_93
VERSION     gnlProkkaIPFFCMEA_93
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 18:50:22
            Original ID  :: gnl|Prokka|IPFFCMEA_93
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14080
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..114
                     /locus_tag="ctg93_1"
                     /transl_table=11
                     /translation="MRFLYKLRTKPEDFVLLIVITFFPEPIRRSAEAHCSA"
     protocluster    1..14080
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2468:4080]"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2469..4080
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     cand_cluster    1..14080
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14080
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="sactipeptide"
                     /region_number="1"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     CDS             complement(59..1729)
                     /locus_tag="ctg93_2"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLETPKDKTHGD
                     YSTNMAMQLARVAKKAPRQIAEEIVAHFDKGKASIEKLDIAGPGFINFYMNNQYLTKLI
                     PSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRF
                     VNEEESERLAFFREYGLKYELEKLRKDLENFRVPFDVWYSETSLYQNGKIDKALEALRE
                     KGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWG
                     ADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKP
                     AADLDFSHIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     CDS             complement(1726..2154)
                     /locus_tag="ctg93_3"
                     /transl_table=11
                     /translation="MKQETPITLHVKSVIEDDGNQEVIEFRTTGFYYVKQNKVYLSYYE
                     EHDLGKVKTIVKVSEGEVLVMRSGAVKMNQRFVKGASTIAKYKMSFGELELKTSTKSIQ
                     SDLDEEKGRISIAYDMHVGDEQEHLHNMTITYEGGTHA"
     CDS             2469..2600
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_functions="biosynthetic-additional (sactipeptides)
                     predicted sactipeptide"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg93_4"
                     /sec_met_domain="Subtilosin_A (E-value: 1e-30, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       2469..2498
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="ctg93_4_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       2499..2600
                     /prepeptide="core"
                     /locus_tag="ctg93_4_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="33.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[2468:2498](+)"
     CDS             2734..4080
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg93_5"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1081.4, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 5.6e-31,
                     bitscore: 98.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.7e-09, bitscore: 28.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.2e-23, bitscore: 75.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 5.8e-12, bitscore:
                     37.5, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.8e-11, bitscore: 36.0,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIEQMFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLN
                     KTAYELCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQLGNRAIR
                     HTITTSGSNEFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSIEQFKKTADMLFDN
                     GVLTCEITGGEIFVHPNANEILDYVCKKFKKVAVLTNGTLMRKESLELLKTYKQKIIVG
                     ISLDSVNSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKV
                     RDLGAKAFSYNWVDDFGRGRDIIHPTKDAEQHRKFMEYEQNVIDEFKDLIPIIPYERKR
                     AANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFNSPLVHKLWQAQAPRF
                     SEHCMKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     CDS             4093..4254
                     /locus_tag="ctg93_6"
                     /transl_table=11
                     /translation="MSPAQRRILLYILSFIFVIGAVVYFVKSDYLFTLIFIAIAILFGM
                     RARKADSR"
     CDS             4251..4970
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 125.6; E-value:
                     4.3e-38)"
                     /gene_kind="transport"
                     /locus_tag="ctg93_7"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYERDNVILEQVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGRFTLCGIEAEAGMPQKTSDQQKTHRYFAADYPLLFTEITAKDYVS
                     FVHSLYQKDFSEQQFASLAEAFHFSKYINRRISELSLGNRQKVVLMTGLLLRAPLFILD
                     EPLVGLDVESIEVFYQKTREYCEAGGTILFSSHLLDVVQRFCDYAAILHNKQIQKVIPI
                     GEETDLRREFFEVIGHE"
     CDS             4963..6273
                     /locus_tag="ctg93_8"
                     /transl_table=11
                     /translation="MNNIIPIMSLLFKQLYSRQGKKDAIRIAAGLVILAVFEIGLIRQA
                     GIDESVLRKTYIILALLLMNAYMVFLSVTSQWKESYMKLSCLLPISSRSFWLAQSVVLF
                     VDTCLRRTLFFFILPLFLFGNGTLSGAQTLFWLGRFSFFTVYSIIFGVVLSNHFVKKKN
                     LMFLLHAAIFACVCLSAALMPAATLPLCAVHMLWAVVIDFPVFLQAPPQQSRMHSFMRR
                     SEFSFYKREWNRFISSKAMLLNYAVMAAFSGFFSFQMMNTGIFNQQVIYIVISALLLIC
                     SPIALLYSIEKNDRMLLITLPIKGKTMFWAKYRFYSGLLAGEFLLVVMIVGFISGRPIS
                     VLTFLQCIELLLAGAFIRLTADEKRPFFSWQTEQQLWSGFSKYRSYLFCLPLFLATLAG
                     TAVSLAVIPIAGLVIVYYLQKQDGGFFDTSKRERLGS"
     CDS             6239..7423
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg93_9"
                     /sec_met_domain="Peptidase_M16_C (E-value: 6e-07, bitscore:
                     21.2, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQAKENGLEVNLLKTHQFSTISIAASFLKPIESAAEPEEETIYF
                     YGAAAYLKEQIIDDFGCAAGSRFMYSANLFFDQQLKTCGTRLIHPLYNGNLHVDALMKT
                     FADLSFPSSLSFEAVEKARNELLLKIEKKFTDPFSYSAARLAEEVFGNPMYGTGMFGRK
                     DRIKAIHPKRFHDATDFIVDLVSQQKQLNILGQVQACDVRGHAPQTSAVTSERIPVNRH
                     VFETETRSAAGPSVLTLGFDCGEMKDASDYIKIQLIDGLLGKYGHSALFKHFREKDLAV
                     YHVITRYDVMNNLLLVSICTDQLHEIDIPPRVLEAVSAFHTDERELEQAKQFLRNELLL
                     QFDSPEGLLAYMGILRRFSCTKEALLDGISAVTCRDVLQFIATINYIGAHVVRG"
     CDS             7428..8708
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg93_10"
                     /sec_met_domain="Peptidase_M16 (E-value: 2.8e-15, bitscore:
                     48.2, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKAFFQQLDERTDIRYTDSGLKIFRLKFPRAHLRLCNVKIDFG
                     SRDVCIRAESGDTLLPYGTAHFLEHLLFWHNGRNLYSDFFAHGALLNAFTTYTDTNFMF
                     TSLPDRLRQTIPILLDALWNHSFDKKIVAQEKAVITSEIQTAHLNHQLSYHYQLISMLS
                     PSSPAAVFPAGRIEDIEALDISDLQKAYKAAYQTHRMTLFLIGGSENTETLLPPHLQLE
                     KRPDYHAERKIIPACPPALSQKMMLGDEERMEDTWTGLQIGALPGQNDLLTIKLYWDIA
                     ARILFQLDSPFFQEIQQTYRLEIDRLSAETYIYEDGGFLILHSQGTHSSAYIDVASYYV
                     TQKKEQAAAWLQYGKDSLTDAIIYDSDYVRKCFEWAAECDRCDCSFLDMYHIIQDMDAQ
                     VFLSLIDAMASSNKAIIHVSQKEAIRQ"
     CDS             8705..9406
                     /locus_tag="ctg93_11"
                     /transl_table=11
                     /translation="MKKNTVFTLLLLLIGMAAYSFGWVQAVAEAAAHYIQMINNDAVRL
                     GLLACTAALLMLPAFLYLHYVTQSVKNMTAAFQKLTQSHQSCCDFQQHNLCSRYAEDVK
                     SLRDGYKNVRQTYVMAAVLCQVIIFGCMFEIVKAVPFRLHTPPALSMGLAMLLILYLLF
                     CMRTYLRQLFRHGSLFRKVFAGVLAAAGIWWMLSFTISELLFLIILAAIQQIRSFIYKR
                     FSYRSTASLDL"
     CDS             complement(9412..10788)
                     /locus_tag="ctg93_12"
                     /transl_table=11
                     /translation="MKKNDLSALQENCFCFCDEEISREAPFQVPIDIPKGFKVDSAEAS
                     AAVTWSTDNLSCVSEPCLIQTGPETEDIGVRYAVRVQGTIMLLVSVSPVRNQYGQGDGA
                     VSVIHTEEIDQVVYYAAQSDRCPDFSQMTVEDLLIVPPFYGSPLTVAGTLVLPPSPDPQ
                     SYVFTANTGDSTVSVIDADLNTVVKTILFSAVPTNLGVTFDKAFTYVLHGNTNLVSVID
                     NKTLTIINTITVGGGPRKIEFDPTDEYAYVMAAGSIYMIDTANQSVIDVIAIPGALDFA
                     LDPNGQYVYTANGSSWSVDKYDVNTGQLVESIIDSFEFPSLIATPYAGNFAYVLNGELW
                     PKGVTEISLSPLSRGGDFNRLFETLRTIVFSLDSTRAYFLEPYSEPFLINNLYVVNTAR
                     QRIIANVPLPGAFDPAVTPDKQYIYAAQPNDNAVTVYRTSDYTAVKVIPVGAGPSAIVM
                     "
     CDS             complement(10827..11312)
                     /locus_tag="ctg93_13"
                     /transl_table=11
                     /translation="MFAYVLNFGLVQKVDLSTGEVTGTIERELIVSSIETDSPERYAYV
                     LEQEFLFNYLTVIDLNTFTISNTQELEPDGQYRMFTSGTGVYLYDDFTGNLYSVSPNGA
                     GVIGNLPQSATDYAFTPNGDFLYATRFIEQSIIVYNTDDYSEETVISLGVSPGAITI"
     CDS             complement(11345..12178)
                     /locus_tag="ctg93_14"
                     /transl_table=11
                     /translation="MRKNKLSFKEKAGAEQEECLCFCEGEASREAMFQAPIELPEGFVV
                     DPAEAVANVTWNADSLSCVSDRCLIQTGPEPDEVGVQFAVRLQGTVTLLVSVSPVRNQY
                     GQGDGAVSVIHNAEIDQVVYYSDEPDDCPDISNITIENLVVVPPFYGSPLSVTGTIVLV
                     PEPEPVYAFTANPNDQSVSVIDTNTHTVVTTIALPYNPAGIEITPDKSAVFVLHPNNNV
                     ISVIDYDTLTVTATILLDQPPRLIRFIPNHEFAYVFTGTAIYVIGIDTLTVERSI"
     CDS             12408..13553
                     /locus_tag="ctg93_15"
                     /transl_table=11
                     /translation="MTGVISSSSIGEKINEWYMYIRRFSIPDAEYLRREIKQELDQMEE
                     DQDLHLYYSLMEFRHNLMLEYLEPLEKMRIEEQPRLSDLLLEIDKKQARLTGLLEYYFN
                     FFRGMYELDQREYLSAIKFFKKAESKLIFVKDRIEKAEFFFKMSESYYYMKQTYFSMDY
                     ARQAYEIYKENEAYNIRLLQCHSLFATNFLDLKQYEDAVSHFQKAYSMAEAEKQPQLMG
                     RTLYNIGLCKNSQSQYEDAITYFKRAIAVFEESNILPSLPQAYFLITQIHYKLGKMDKA
                     HEYHSKGMAYSQKAGDVIYLSEFEFLKSLYLSGPDEEAIQGFFDFLESKMLYADLEDFT
                     IDVAKYYHERKNFQKASAYFLKVEQVRQLIQGGVSLYEIEV"
     CDS             13537..13656
                     /locus_tag="ctg93_16"
                     /transl_table=11
                     /translation="MKLKSKLLLSCLALSTVFVATTIANAPTHQIEVAQRGMI"
     CDS             13754..14065
                     /locus_tag="ctg93_17"
                     /transl_table=11
                     /translation="MSLKSVRTHFTQWNRENDVTEFETSSATVEQAAETIGVSLSRIAK
                     SLSFRGEGDQVILIVAAGDAKIDNKKSRQTFGFKARMLSPNEVLEQTGHEIGGVCPIG"
ORIGIN
        1 cgtcgttttc tctacaagct aaggacaaag cccgaagact ttgtcctttt gatcgtgatt
       61 acattttttc cggagccgat acgccgatca gctgaagcgc attgttcagc gtaatttgcg
      121 ttgccttcat taaagccagg cgcgcacggc ttttctcttc attttcaggg tcgatgactt
      181 tctctgcgtt gtagaagctg tgcagagcag aggccagatc ataaatatag tttgtgacac
      241 ggtgcggaat tcgtttttcc gctgcttccg ccactgcctc tgggaagccg ccgatcgttt
      301 tcagcagatc gtattctttt tctgattgaa tatggctgaa atcaagatcc gccgccggtt
      361 taagtccctg ctcttcccct tggcgaagca tgctgcagat tcgggcatgt gcatattgtg
      421 cataatacac agggttttcg ttagatgttg atacagcaag atctaagtca aaatccatat
      481 gggtgtccgc acttcgcatc gcaaagaagt aacgaacggc atccaagccg acttcttcaa
      541 tcaggtcacg catcgttacg gctttaccgg tccgtttgct cattttcatt ttctcgccgt
      601 ttttgtaaag gtgaacgagc tgaatgattt ctacttcaag cgttcctttt tcatagccca
      661 gcgcttcgat tgccgctttc atacgcggga tgtagccgtg gtgatcggcg ccccaaacgt
      721 tgatcagctt atcaaagccg cggtcaagct tgtccttatg atacgcgata tcaggaagca
      781 ggtacgtgta cgtgccgtcc ttcttgatca atacgcggtc tttatcatcg ccaaacgtcg
      841 tggaacggaa ccaagtcgcg ccgtcttctt catagacatg gcctttttcg cggagcgctt
      901 caagcgcctt gtcgattttt ccattttggt acagtgaagt ttctgaatac cacacatcaa
      961 acggcacacg gaagttttcc aagtccttgc gaagcttttc cagctcatat ttcaggccgt
     1021 attcacggaa aaacgcgagg cgttcacttt cttcttcgtt aacgaaacga tcaccgtatt
     1081 cctcagcgag acgctttccg atcgcaatga tatcctcgcc gcggtagcca tcctccggca
     1141 tcggtttttc caatccgagt gcttcaaagt aacggacttc aacagaaagc gccagattgt
     1201 tgatttggtt acccgcatcg ttaatgtagt attcgcggct tacatcgtaa cccgcttttg
     1261 aaagcacgtt gcacaaggaa tcgccgacag ccgccccgcg cgcatgcccg aggtgaaggt
     1321 ctcccgtcgg attcgctgat acgaattcta cctgaactcg ttcaccgttt ccgatgttcg
     1381 tttccccgta tgcttcccct gcttccagta cagacggaat cagctttgtt aaatattgat
     1441 tgttcatata gaaattgata aaacccgggc cggcgatatc cagtttttca atcgaagcct
     1501 ttcctttatc aaaatgggcg acaatctctt cagcgatttg gcgcggcgct ttttttgcca
     1561 ctcttgccag ctgcatcgcc atattcgttg agtagtcgcc gtgtgtttta tctttcggtg
     1621 tttctaaaac aacattggga atctggcttt cttcagccag tcccgctttc agaacggccg
     1681 ctttgatttc ttctttcagc acgtccttca tttgttccgc aatgttcatg cgtgagttcc
     1741 tccctcatac gtgatcgtca tattatgtaa atgctcctgc tcgtctccga catgcatgtc
     1801 atatgcgatg ctgatacggc ctttttcttc atcgagatca gattgaatcg attttgtgct
     1861 tgttttcagc tcaagctcac caaatgacat tttatattta gcaattgtgg aagctccctt
     1921 tacgaaacgc tgattcattt tgacagcgcc tgacctcatg accaggactt cgccttcgct
     1981 tactttcaca atcgttttga ctttgcctaa gtcgtgttct tcataataag atagatacac
     2041 tttattttgt tttacatagt aaaatccggt ggtgcggaat tcgatgactt cttggtttcc
     2101 gtcatcctcg atcacagact tcacatggag tgttatcggt gtctcttgct tcattctgac
     2161 acgtcctttt catcattcca ctttgacttg aatagtataa tcattcggtt tgtaaacttc
     2221 aactgcttct atcttaccat cattgctcat cagatttgaa gataaacctc ataaaaagca
     2281 tttccttata tagaagagaa aatcatatca ctaattacct ttagtaaatg ttacattttt
     2341 ccgaaatcta tcatttcctt ttcacatttt tttcaaaata tatgtattga attagtaatt
     2401 tgatagtttt aagataaaag tacaacatag atctgttaga aaaacaaaaa aaaagggagg
     2461 attcaattat gaaaaaagct gtcattgtag aaaacaaagg ttgtgcaaca tgctcgatcg
     2521 gagccgcttg tctagtggac ggtcctatcc ctgattttga aattgccggt gcaacaggtc
     2581 tattcggtct atgggggtaa ggatctccca aaagggcata gtcattctac tatgcccttt
     2641 ttaagtaaat tacaattttt aactaaaatc tacctcttgg atatacatac acaaccgttt
     2701 ttcatttgaa tcatatgtat aggggatggt attttgttta tagagcagat gtttccattt
     2761 attaatgaaa gtgtaagagt tcaccagctt cctgagggcg gcgtgttaga aatcgactac
     2821 ttgcgcgata atgtctccat ttctgacttt gagtatttgg atctcaacaa aacagcttac
     2881 gagctctgca tgcgcatgga tggccaaaaa acagctgagc agattttagc tgagcaatgt
     2941 gcagtgtatg atgaatcacc ggaagaccat aaagattggt attacgacat gctcaacatg
     3001 ctccagaaca agcaggttat ccagcttgga aaccgggcca tccgccatac catcaccacg
     3061 agcggaagca atgaatttcc gatgcccctg cacgccacct ttgaactgac gcaccgctgt
     3121 aatttgaaat gcgcccactg ttatttggaa agctcgcctg aagcgctcgg caccgtgtcg
     3181 attgagcaat tcaaaaaaac ggctgatatg ctgtttgata acggtgtatt gacatgcgaa
     3241 atcacaggcg gagaaatttt tgtccatcca aacgccaatg agattcttga ctatgtgtgt
     3301 aaaaagttca aaaaagtcgc tgtcttaaca aacggaacac tcatgcgaaa agagagcctg
     3361 gagcttttga agacttacaa gcaaaaaatc atcgtcggca tttctcttga tagtgtcaat
     3421 tccgaggtcc atgactcctt tagagggaga aaaggctctt ttgcccaaac ttgtaaaacg
     3481 ataaaattgt tgagtgacca cggtatattt gtcagagtcg ccatgtctgt cttcgaaaaa
     3541 aacatgtggg aaatccacga tatggcccaa aaggttcggg atctcggagc gaaggcgttt
     3601 tcttacaatt gggttgacga tttcggaaga ggcagggata ttatccatcc aacgaaagac
     3661 gccgagcagc accgcaagtt tatggaatac gagcaaaatg tgattgatga gtttaaagat
     3721 ctgattccga ttattcccta tgagagaaaa cgcgcggcaa attgcggcgc tggctggaag
     3781 tccattgtga tcagcccgtt cggcgaagta cgtccttgcg ccctctttcc aaaggaattt
     3841 tcattgggaa atatttttca tgattcctat gaaagcatct ttaactcccc tctcgtccat
     3901 aaactgtggc aagcgcaggc gccgcggttc agcgaacatt gcatgaaaga caaatgcccg
     3961 ttcagcggct attgcggagg ctgttactta aaagggctga actctaacaa atatcaccga
     4021 aaaaacattt gctcttgggc gaaaaatgaa caattagaag acgtggtcca gcttatttag
     4081 gagggaaacg atttgtcacc agcacaaaga agaattttac tgtatatcct ttcatttatc
     4141 tttgtcatcg gcgcagtcgt ctattttgtc aaaagcgatt atctgtttac gctgattttc
     4201 attgccattg ccattctgtt cggaatgcgc gcgcggaagg ctgactcgcg atgagcattt
     4261 tggatataca cgatgtatcc gtttggtatg aacgggacaa cgtcatctta gaacaagtgg
     4321 atttacattt agaaaaaggc gccgtttacg ggctgcttgg ggtaaacggc gccggaaaaa
     4381 cgacactgat taatacgctg acaggcgtga accgcaattt cagcgggcgc tttacactgt
     4441 gcggaattga agcggaggcc ggcatgccgc agaaaacatc agatcagcag aagactcacc
     4501 gttacttcgc cgccgattat ccgctgctat ttacagaaat tacggcgaag gactatgtgt
     4561 ctttcgtcca ttcgctttat caaaaggatt tttcagagca gcagtttgcc agtttggccg
     4621 aggcctttca tttttcgaaa tacatcaaca ggagaatttc ggagctgtcc ttggggaaca
     4681 ggcaaaaggt tgtattgatg acaggcttat tgctgcgcgc tcccctattt attttggatg
     4741 agccgctcgt cggtttggat gtggaatcga tagaggtttt ttatcagaaa acgcgcgagt
     4801 actgtgaagc aggcgggacc attttgtttt cttctcatct gctcgatgtc gtgcaaagat
     4861 tttgtgatta cgcggccatt cttcacaaca aacagatcca aaaggtcatt ccgattggag
     4921 aggagaccga tctgcggcgg gaatttttcg aggtgatcgg ccatgaataa cataatcccc
     4981 atcatgtctt tgctgttcaa acagctttac agccggcaag ggaaaaagga cgccatccgc
     5041 attgccgcag gccttgtcat tctggccgta tttgaaatcg ggctgatccg ccaggccggc
     5101 attgatgaat cggtgttgcg caaaacgtat atcatactcg cgcttctctt aatgaacgca
     5161 tatatggtgt ttctttctgt gacatctcaa tggaaggaat cttatatgaa actgagctgc
     5221 ctgctgccga tttcttcacg gagcttttgg ctcgcccaga gtgtcgtttt gtttgtcgat
     5281 acctgtttga gaagaacgtt attctttttt attttaccgc tgttcttatt tggaaacgga
     5341 acgctgtcag gggcgcaaac attgttttgg ctcggcaggt tttcgttttt taccgtttac
     5401 tccattattt tcggagttgt gctaagcaac cacttcgtca aaaagaagaa cttgatgttt
     5461 ctgctgcatg cggcgatatt cgcctgtgta tgtctcagcg ccgctttgat gccggccgcc
     5521 acgcttccgc tttgcgcggt gcatatgctg tgggcggtgg tcattgactt tcctgtcttt
     5581 ctgcaggcgc ctccgcagca gagcaggatg cattcattta tgcggcgatc tgagttttcg
     5641 ttttacaaaa gagaatggaa ccgatttatc tcttctaaag cgatgctgtt aaattacgcg
     5701 gtaatggcgg cgttcagcgg cttcttttcg ttccagatga tgaataccgg catcttcaat
     5761 cagcaagtga tttatatcgt gatttccgcg cttctgctca tctgctcgcc gatcgccctt
     5821 ttgtactcga ttgaaaaaaa tgaccggatg ctgctcatca cgcttccgat caaggggaaa
     5881 acgatgtttt gggcgaaata tcgcttttat tcaggcctat tggcaggcga atttctcctt
     5941 gtcgtgatga ttgtgggttt catcagcggc cgtccgattt cagttctcac ttttttgcag
     6001 tgcattgagt tgctgctggc gggagctttt atcaggttaa ctgcggatga aaaaaggccc
     6061 ttcttcagct ggcagacgga gcagcagcta tggagcggtt tctcaaaata tcggtcttat
     6121 ctgttttgtc ttcccctatt cttagccaca ttagccggca ccgctgtatc cttggcggtc
     6181 attccgatag ccggtctggt catagtctat tacctgcaaa aacaggatgg tggtttcttt
     6241 gatacaagca aaagagaacg gcttggaagt taacctgctg aagactcatc aattttcaac
     6301 tatatcaatc gccgcgagct ttctgaaacc gatcgaaagc gcggcggaac ctgaggaaga
     6361 aacgatttat ttttacggcg ccgccgcata cctgaaggag caaatcattg acgatttcgg
     6421 ttgtgctgcc ggcagccgtt tcatgtactc agcgaatctc ttttttgatc agcagctgaa
     6481 aacctgcggg acccgtttga ttcacccatt atataatggg aatcttcatg ttgacgccct
     6541 gatgaaaact tttgcagact tgtctttccc ttcttctctt tcattcgaag cagttgaaaa
     6601 ggccaggaat gagctgctgc tgaaaatcga aaagaaattc actgatccct tctcctactc
     6661 ggcggcgcgc ttggctgagg aggtcttcgg aaacccgatg tacggcacag gcatgtttgg
     6721 ccggaaagac aggataaagg cgattcatcc taaacggttt cacgacgcaa cggactttat
     6781 cgttgattta gtgtcccagc aaaaacagct gaacatattg ggacaagtac aagcatgtga
     6841 tgttcgggga catgccccgc aaacgtccgc tgtaacgtcc gaaagaatac ccgtaaaccg
     6901 gcatgttttt gaaacagaga cacgcagcgc tgcaggtcct tccgtcttga cactcggatt
     6961 tgactgcgga gagatgaaag atgccagcga ttatatcaaa atacagctaa tagacggatt
     7021 actgggaaag tacggccatt ccgctttatt caagcacttc agagagaaag atctggcagt
     7081 ctatcacgtt atcacccgtt acgatgtcat gaacaatttg ctgcttgttt caatatgtac
     7141 agatcagctt catgagatag acattccccc gcgcgttttg gaagctgtct cagcttttca
     7201 tacagatgag cgggaactag aacaggcaaa gcagttttta cgcaatgaat tgctgctgca
     7261 attcgattct cccgaaggtc tattggccta tatggggatc ctgcgccgct tctcctgcac
     7321 gaaagaagcc ttgctggatg gcatctcagc ggttacatgc cgtgatgtat tgcaattcat
     7381 agcgaccatc aattatatcg gagctcatgt agtaagggga tgaaaagatg gaaaagaaag
     7441 ccttttttca acagctggat gaacgaaccg atatcagata cacagacagc ggactaaaaa
     7501 tattcagatt gaaattcccc cgcgcccacc tgcggctgtg caatgtaaaa atcgattttg
     7561 gaagccggga tgtatgtata cgggcagaat ccggtgatac actgcttccg tatggcacag
     7621 cgcatttttt agagcatctt ctcttctggc ataacggccg caatctgtac agtgattttt
     7681 ttgcgcatgg cgcgctttta aacgcattca ctacctacac cgataccaat ttcatgttta
     7741 cctcattacc ggatcggctc agacaaacga tccccatcct gcttgatgct ttatggaacc
     7801 actcatttga caagaagatt gtcgctcagg aaaaagctgt gattacaagc gaaattcaaa
     7861 cagcacacct taaccatcag ctctcatatc attatcagct gatcagcatg ctttctccct
     7921 cctcaccagc tgccgttttc cccgcaggca gaatcgaaga tattgaggcg cttgacatca
     7981 gtgatttaca aaaagcctat aaggctgcct accaaaccca tcggatgacg ctgtttttga
     8041 ttgggggctc agaaaataca gaaacgctat tgcctcctca cctccagctg gaaaagcgtc
     8101 cggattatca tgctgaaaga aaaatcatcc cggcatgccc tccagccctc tcacaaaaaa
     8161 tgatgctggg tgatgaggag cggatggaag atacatggac cggattacag atcggcgcac
     8221 ttcccgggca aaacgatctg ttgacgatca aactttattg ggatatcgcg gctcgtattc
     8281 tatttcaatt agattcaccg ttttttcaag agattcagca aacgtaccgc ctggaaatcg
     8341 atcgtttgtc agccgagact tatatctatg aggatggcgg tttcttgatc cttcacagtc
     8401 aagggaccca ttcttcagct tatatcgatg tggcttcata ctatgtcaca cagaagaaag
     8461 aacaggctgc cgcctggctt caatacggca aggactcttt gacagacgcg atcatttatg
     8521 acagcgatta tgtgcgtaaa tgcttcgagt gggcagccga gtgtgacagg tgcgattgct
     8581 cgtttcttga catgtaccac atcattcaag atatggatgc gcaggttttc ttgtctctca
     8641 ttgatgcaat ggcatcttct aacaaagcga tcattcacgt ttctcagaaa gaggcgatca
     8701 gacaatgaaa aaaaacactg tctttaccct tttattgctg cttataggta tggcggctta
     8761 ttccttcggc tgggttcagg ccgttgccga agccgccgcc cactatatac agatgatcaa
     8821 caatgatgct gtacggctcg gactgctggc ttgtaccgct gccctcctga tgctgcctgc
     8881 ttttctctat cttcactatg tcacccaatc tgtgaaaaac atgacagcag cttttcagaa
     8941 actcacacag tctcatcaaa gctgctgtga ctttcagcaa cacaacttgt gcagccgata
     9001 tgcagaagac gtcaaatcgc tgcgtgacgg ctataaaaac gtccgccaaa catacgtgat
     9061 ggctgccgtg ttgtgccaag tcatcatatt cggctgcatg ttcgaaatcg ttaaagccgt
     9121 ccctttccgc cttcacacgc cccctgccct ttcaatggga cttgcgatgc tactgatcct
     9181 gtatttattg ttttgcatgc gaacgtattt gcggcagctt ttccggcacg gcagcctgtt
     9241 cagaaaagtg tttgcgggag tgctggcagc agccgggatt tggtggatgc tcagtttcac
     9301 tataagtgaa ctgctgtttc tgattatcct ggctgccatc cagcaaatca gatcatttat
     9361 ttataagcga ttctcttatc gcagcaccgc ttctcttgat ctataaaata gctacatcac
     9421 aatcgcagac gggcccgcgc caaccggaat caccttcacg gctgtataat cacttgtgcg
     9481 gtacacagtc acagcattgt cgttgggctg tgccgcataa atatactgtt tgtccggcgt
     9541 tacggcgggg tcaaaagcgc cggggagagg cacgtttgca atgatcctct gtctggccgt
     9601 attaactacg tataagttat taatgagaaa cggttcacta tatggctcta gaaaataagc
     9661 tctagtacta tcgagagaaa atacaatcgt cctcagcgtt tcaaataaac ggttaaagtc
     9721 ccctcccctg cttaatggtg acaaactaat ctccgttaca cctttcggcc acagctcacc
     9781 attcaacacg tacgcaaaat ttccagcgta aggagttgca attaaactgg gaaattcaaa
     9841 tgaatctatg atactttcta ccaactgccc agtatttaca tcatatttat caaccgacca
     9901 actgcttcca ttagcggtat agacatactg tccattcgga tcaagagcaa agtctaaagc
     9961 gccgggtatc gcgattacat caattactga ttgattggcc gtgtcaatca tatatataga
    10021 tccggcggcc atcacgtagg cgtactcatc tgttggatca aattcgatct ttctcggtcc
    10081 tcctccaaca gtaatggtat ttatgatggt taatgtttta ttatcaatca ctgagacaag
    10141 gttggtattc ccatggagga catacgtgaa tgctttatcg aaagtaacgc ctagattagt
    10201 tggcacagca gaaaacagga ttgtttttac aacagtgttt aaatctgcat caatgaccga
    10261 aaccgtgctg tctccagtat tggcagtaaa cacatacgat tgagggtctg gcgatggcgg
    10321 caaaacaagt gtcccggcca ccgtgagcgg actgccgtag aaaggcggca cgatgagaag
    10381 atcttccact gtcatctgac taaaatcagg acagcggtca gactgtgctg cataataaac
    10441 aacttgatca atctcttcag tatgaatcac agaaaccgcc ccgtctcctt gtccatattg
    10501 atttcgcaca ggcgacacac tgacaagaag cataatggtc ccttgtactc tcacagcata
    10561 tcgaacacca atatcttctg tttccggccc agtctggatt aagcaaggct cactgacaca
    10621 ggacaaattg tctgtactcc atgtaacagc cgctgacgct tcggctgaat caaccttgaa
    10681 gcccttaggg atatctattg gcacttgaaa cggcgcttcc cggctaattt cctcatcaca
    10741 aaaacagaaa caattttcct gtaaagcaga aagatcattc tttttcatga attcacgtcc
    10801 ttttaaaaat gcacaacatg cagcggttaa atcgtaatgg cacccggtga aaccccaaga
    10861 gatatcacag tttcctcaga ataatcatct gtgttgtaaa caatgatgct ctgctctata
    10921 aaacgagttg catacagaaa atcgccattc ggggtaaacg catagtctgt tgctgattgc
    10981 ggaagatttc caattacacc tgctccattc ggactgacag aatataaatt gccggtaaag
    11041 tcgtcatata aatacacacc tgttccgctc gtaaacattc tatattggcc gtcaggctcc
    11101 agttcttggg tattgctgat cgtaaacgta tttaagtcaa taaccgtcaa ataattgaat
    11161 aagaattctt gttctaagac atacgcatac cgctccggag aatctgtttc tatggatgat
    11221 acgataagct ctcgttcaat cgttcctgtg acttcaccgg tggataagtc cactttttgc
    11281 actaacccaa aattaagaac ataggcgaac aacccattgg ggtcaattgc aatatcaaaa
    11341 ccttctatat agacctctca acagtcaacg tatcaattcc aatcacataa atggcagtac
    11401 cggtgaaaac ataagcaaac tcatgattag ggataaatct aatcaatcga ggcggctgat
    11461 ccagcaatat agttgctgtc actgttaatg tgtcataatc gatgacagaa atcacattat
    11521 tgttgggatg taagacaaac acagcgcttt tatctggcgt aatttcaata cctgccggat
    11581 tgtacggaag agcaatcgtt gtcacaacag tatgggtgtt tgtatcaatc acagaaactg
    11641 attgatcatt tggattcgct gtaaacgcgt agacgggttc cggctccggt acaagcacaa
    11701 tcgtccccgt caccgataaa ggactgccgt aaaacggcgg aacaacaaca aggttctcaa
    11761 tcgtgatgtt actgatatcc gggcaatcat ccggttcatc ggaataatag acgacttgat
    11821 cgatttctgc attgtgaatg acggaaacag ccccatcccc ttgtccatat tgatttcgca
    11881 caggtgagac actgacgagc agcgtaacgg ttccctgcag acgcactgca aattgaacac
    11941 cgacctcatc aggctctggc cccgtttgaa ttaagcaacg gtcactgaca caagaaaggc
    12001 tgtctgcatt ccacgtcacg tttgcaacag cttcagccgg atcaacgaca aatccttcag
    12061 gtaattcaat cggcgcttga aacatggctt ctcggcttgc ttctccctca caaaaacata
    12121 agcactcttc ttgttctgct cctgcttttt ctttaaagga aagcttgttt tttctcattc
    12181 cttcacttcc ttttcagaca tacactgctc acgcagatat aacagaatat ggaagagtaa
    12241 cgtgtttgct tgtacaaatt actgagggta aaagcttctt tttgaaaata tatctccaaa
    12301 catgcggtgt aacgaaagaa aaaattgcgg tttttttgcg cttctcacaa gaatgttgat
    12361 gataaaatat gacatatata gaattatgaa gggagggatt tgcaaacgtg acaggtgtca
    12421 tatcttcttc ttccatcgga gaaaagatta acgaatggta tatgtacata cgccgattca
    12481 gcatacccga tgcagaatat ttgcgacgag aaatcaagca agagctggat caaatggaag
    12541 aagatcaaga ccttcatttg tactattcac tgatggagtt tcggcacaac ctgatgcttg
    12601 agtaccttga accgttagaa aaaatgagga ttgaggaaca gccgagactg tctgatctgc
    12661 tgcttgagat tgataaaaaa caggctcgtt taacaggtct gcttgagtac tattttaatt
    12721 tcttcagagg catgtatgag ctggatcagc gggaatatct gtcggctatt aaatttttca
    12781 aaaaggccga aagcaagctg atattcgtta aggatcggat agagaaagct gagtttttct
    12841 ttaagatgtc tgaatcttat tactatatga aacaaacgta tttttcaatg gactatgcac
    12901 ggcaagcata tgaaatatac aaagaaaatg aagcttataa tataagattg ctgcagtgtc
    12961 attctttatt tgccaccaat tttttagatt taaaacagta tgaggatgcc gtctcacatt
    13021 ttcaaaaagc ttattctatg gcagaagctg aaaagcagcc ccaattaatg ggaagaactt
    13081 tgtacaatat cgggctttgt aaaaacagcc aaagccaata tgaggatgcc ataacatatt
    13141 tcaaaagagc aatagctgtt tttgaagaat caaatattct tccttcctta cctcaagcgt
    13201 attttttaat tacacagatc cattataaat taggaaaaat ggataaagct catgaatatc
    13261 atagtaaggg aatggcttat tcacaaaagg ccggagatgt aatatattta tcagagtttg
    13321 aatttttgaa atctttatac ttatcaggcc cggatgaaga agcaattcaa ggattttttg
    13381 attttctcga aagtaaaatg ttgtatgctg atcttgaaga tttcactatt gatgtggcaa
    13441 aatattatca tgaacgtaaa aattttcaaa aagcttctgc ttattttttg aaggtggaac
    13501 aagtaaggca acttattcaa ggaggagtga gtttgtatga aattgaagtc taaactatta
    13561 ctctcttgtc tggctctaag cactgtgttc gtggcaacaa ctattgcaaa tgcacctaca
    13621 caccaaattg aagttgcaca acgaggaatg atttaaccgc cgtccatcgg cggttttttt
    13681 gtcccctctt tacccagtct cccaatccat tctatgattt tttcaataat cttaaaaata
    13741 gtggaaatgc agcatgtctc taaaaagtgt gagaacccac tttactcaat ggaatcgaga
    13801 aaatgatgtg acggagttcg aaacgtcgag tgcgacagtt gaacaggcag ctgagacaat
    13861 cggcgtaagc ctgtctagaa tcgccaagtc cctgtccttc agaggggaag gagatcaggt
    13921 gattctgatt gtggcagccg gcgatgccaa gatcgacaac aaaaagtcca ggcaaacatt
    13981 tggctttaaa gcaagaatgc tctctcctaa tgaggtactg gagcagacag gccatgaaat
    14041 tggaggagtt tgcccaattg gatagactca tgatcctgag
//
