LOCUS       gnlProkkaGAMLCGEA_34   14291 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GAMLCGEA_34.
ACCESSION   gnlProkkaGAMLCGEA_34
VERSION     gnlProkkaGAMLCGEA_34
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 19:36:14
            Original ID  :: gnl|Prokka|GAMLCGEA_34
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14291
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14291
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2679:4291]"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2680..4291
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     cand_cluster    1..14291
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14291
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="sactipeptide"
                     /region_number="1"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     CDS             133..306
                     /locus_tag="ctg34_1"
                     /transl_table=11
                     /translation="MGALFLHLKPDEYLKKLYKTKKLVEKTSFSLQAKDKVRRLCPFVR
                     DYIFSGADTPIS"
     CDS             complement(270..1940)
                     /locus_tag="ctg34_2"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLEIPKDKTHGD
                     YSTNMAMQLARVAKKAPRQIAEEIVAHFDKGKASIEKLDIAGPGFINFYMNNQYLTKLI
                     PSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRF
                     VNEEESERLAFFREYGLKYELEKLRKDLENFRVPFDVWYSETSLYQNGKIDKALEALRG
                     KGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWG
                     ADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKP
                     AADLDFSHIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     CDS             complement(1937..2365)
                     /locus_tag="ctg34_3"
                     /transl_table=11
                     /translation="MKQETPITLHVKSVIEDDGNQEVIEFRTTGFYYVKQNKVYLSYYE
                     EHDLGKVKTIVKVSEGEVLVMRSGAVKMNQRFVKGASTIAKYKMSFGELELKTSTKSIQ
                     SDLDEEKGRISIAYDMHVGDEQEHLHNMTITYEGGTHA"
     CDS             2680..2811
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_functions="biosynthetic-additional (sactipeptides)
                     predicted sactipeptide"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg34_4"
                     /sec_met_domain="Subtilosin_A (E-value: 2.2e-30, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       2680..2709
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="ctg34_4_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       2710..2811
                     /prepeptide="core"
                     /locus_tag="ctg34_4_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="33.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[2679:2709](+)"
     CDS             2945..4291
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg34_5"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1081.4, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 1.2e-30,
                     bitscore: 98.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 8.1e-09, bitscore: 28.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.6e-23, bitscore: 75.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1.3e-11, bitscore:
                     37.5, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 4e-11, bitscore: 36.0,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIEQMFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLN
                     KTAYELCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQLGNRAIR
                     HTITTSGSNEFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSIEQFKKTADMLFDN
                     GVLTCEITGGEIFVHPNANEILDYVCKKFKKVAVLTNGTLMRKESLELLKTYKQKIIVG
                     ISLDSVNSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKV
                     RDLGAKAFSYNWVDDFGRGRDIIHPTKDAEQHRKFMEYEQNVIDEFKDLIPIIPYERKR
                     AANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFNSPLVHKLWQAQAPRF
                     SEHCMKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     CDS             4304..4465
                     /locus_tag="ctg34_6"
                     /transl_table=11
                     /translation="MSPAQRRILLYILSFIFVIGAVVYFVKSDYLFTLIFIAIAILFGM
                     RARKADSR"
     CDS             4462..5181
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 124.3; E-value:
                     1.1e-37)"
                     /gene_kind="transport"
                     /locus_tag="ctg34_7"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYERDNVILEQVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGRFTLCGIEAEAGMPQKTSDQLKTHRYFAADYPLLFTEITAKDYVS
                     FVHSLYQKDFSEQQFASLAEAFHFSKYINRRISELSLGNRQKVVLMTGLLLRAPLFILD
                     EPLVGLDVESIEVFYQKTREYCEAGGTILFSSHLLDVVQRFCDYAAILHNKQIQKVIPI
                     GEETDLRREFFEVIGHE"
     CDS             5174..6484
                     /locus_tag="ctg34_8"
                     /transl_table=11
                     /translation="MNNIIPIMSLLFKQLYSRQGKKDAIRIAAGLVILAVFEIGLIRQA
                     GIDESVLRKTYIILALLLMNAYMVFLSVTSQWKESYMKLSCLLPISSRSFWLAQSVVLF
                     VDTCLRRTLFFFILPLFLFGNGTLSGAQTLFWLGRFSFFTVYSIIFGVVLSNHFVKKKN
                     LMFLLHAAIFACVCLSAALMPAATLPLCAVHMLWAVVIDFPVFLQAPPQQSRMHSFMRR
                     SEFSFYKREWNRFISSKAMLLNYAVMAAFSGFFSFQMMNTGIFNQQVIYIVISALLLIC
                     SPIALLYSIEKNDRMLLITLPIKRKTMFWAKYRFYSGLLAGGFLLVVMIVGFISGRPIS
                     VLTFLQCIELLLAGAFIRLTADKKRPFFSWQTEQQLWSGFSKYRSYLFCLPLFLATLAG
                     TAVSLAVIPIAGLVIVYYLQKQDGGFFDTSKRERLGS"
     CDS             6450..7634
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg34_9"
                     /sec_met_domain="Peptidase_M16_C (E-value: 1.4e-06,
                     bitscore: 21.2, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQAKENGLEVNLLKTHQFSTISIAASFLKPIESAAEPEEETIYF
                     YGAAAYLKEQIIDDFGCAAGSRFMYSANLFFDQQLKTCGTRLIHPLYNGNLHVDALMKT
                     FADLSFPSSLSFEAVEKARNELLLKIEKKFTDPFSYSAARLAEEVFGNPMYGTGMFGRK
                     DRIKAIHPKRFHDATDFIVDLASQQKQLNILGQVQACDVRGHAPQTSAVTSERIPVNRH
                     VFETETRSAAGPSVLTLGFDCGEMKDASDYIKIQLIDGLLGKYGHSALFKHFREKDLAV
                     YHVITRYDVMNNLLLVSICTDQLHEIDIPPRVLEAVSAFHTDERELEQAKQFLRNELLL
                     QFDSPEGLLAYMGILRRFSCTKEALLDGISAVTCRDVLQFIATINYIGAHVVRG"
     CDS             7639..8919
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg34_10"
                     /sec_met_domain="Peptidase_M16 (E-value: 6.1e-15, bitscore:
                     48.2, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKAFFQQLDERTDIRYTDSGLKIFRLKFPRAHLRLCNVKIDFG
                     SRDVCIRAESGDTLLPYGTAHFLEHLLFWHNGRNLYSDFFAHGALLNAFTTYTDTNFMF
                     TSLPDRLRQTIPILLDALWNHSFDKKIVAQEKAVITSEIQTAHLNHQLSYHYQLISMLS
                     PSSPAAVFPAGRIEDIEALDISDLQKAYKAAYQTHRMTLFLIGGSENTETLLPPHLQLE
                     KRPDYHTERKIIPACPPALSQKMMLGDEERMEDTWTGLQIGALPGQNDLLTIKLYWDIA
                     ARILFQLDSPFFQEIQQTYRLEIDRLSAETYIYEDGGFLILHSQGTHSSAYIDVASYYV
                     TQKKEQAAAWLQYGKDSLTDAIIYDSDYVRKCFEWAAECDRCDCSFLDMYHIIQDMDAQ
                     VFLSLIDAMASSNKAIIYISQKEAIRQ"
     CDS             8916..9617
                     /locus_tag="ctg34_11"
                     /transl_table=11
                     /translation="MKKNTVFTLLLLLIGMAAYSFGWVQAVAEAAAHYIQMINNDAVRL
                     GLLACTAALLMLPAFLYLHYVTQSVKNMTAAFQKLTQSHQSCCDFQQHNLCSRYAEDVK
                     SLRDGYKNVRQTYVMAAVLCQVIIFGCMFEIVKAVPFRLHTPPALSMGLAMLLILYLLF
                     CMRTYLRQLFRHGSLFRKVFAGALAAAGIWWMLSFTISELLFLIILAAIQQIGSFIYKR
                     FSYRSTASLDL"
     CDS             complement(9623..10990)
                     /locus_tag="ctg34_12"
                     /transl_table=11
                     /translation="MDLSALQENCFCFCDEEISREAPFQVPIDIPEGFKVDSAEASAAV
                     TWSTDNVSCISEPCLIQTGPETEDIGVRYAVRVQGTIMLLVSVSPVRNQYGQGDGAVSV
                     IHTEEIDQVVYYAAQSDRCPDFSQMTVEDLLIVPPFYGSPLTVAGTLVLPPSPDPQSYV
                     FTANTGDSTVSVIDADLNTVVKTILFSAVPTNLGVTFDKAFTYVLHGNTNLVSVIDNKT
                     LTIINTITVGGGPRKIEFDPTDEYAYVMAAGSIYMIDTANQSVIDVIAIPGALDFALDP
                     NGQYVYTANGSSWSVDKYDVNTGQLVESIIDTFEFPSLIATPYAGNFAYVLNGELWPKG
                     VTEISLSPLSRGGDFSRLFETLRTIVFSLDSTRAYFLEPYSEPFLINNLYVVNTARQRI
                     IANVSLPGAFDLAVTPDKQYIYAAQPNDNAVTVYRTSDYTAVKVISVGAGPSAIVM"
     CDS             complement(11039..11485)
                     /locus_tag="ctg34_13"
                     /transl_table=11
                     /translation="MDLTTGEVTGTIERELIVSSIETDSTERYAYVLEQEFLFNYLTVI
                     DLNTFTIRDTQELEPDGLYVMFTSGSEVYLHDSFTGNLYSVSPNGAGVIGNLPQSATDY
                     AFTPNGDFLYATRFIEQSIIVYNTDDYSEETVISLGVSPGAITI"
     CDS             complement(11557..12390)
                     /locus_tag="ctg34_14"
                     /transl_table=11
                     /translation="MRKNKLSFKEKAGAEQEECLCFCEGEASREAMFQAPIELPEGFVV
                     DPAEAVANVTWNADSLSCVSDRCLIQTGPEPDEVGVQFAVRLQGTVTLLVSVSPVRNQY
                     GQGDGAVSVIHNAEIDQVVYYSDEPDDCPDISNITIENLVVVPPFYGSPLSVTGTIVLV
                     PEPEPVYAFTANPNDQSVSVIDTNTHTVVTTIALPYNPAGIEITPDKSAVFVLHPNNNV
                     ISVIDYDTLTVTATILLDQPPRLIRFIPNHEFAYVFTGTAIYVIGIDTLTVERSI"
     CDS             12620..13765
                     /locus_tag="ctg34_15"
                     /transl_table=11
                     /translation="MTGVISSSSIGEKINEWYMYIRRFSIPDAEYLRREIKQELDQMEE
                     DQDLHLYYSLMEFRHNLMLEYLEPLEKMRIEEQPRLSDLLLEIDKKQARLTGLLEYYFN
                     FFRGMYELDQREYLSAIKFFKKAESKLIFVKDRIEKAEFFFKMSESYYYMKQTYFSMDY
                     ARQAYEIYKENEAYNIRLLQCHSLFATNFLDLKQYEDAVSHFQKAYSMAEAEKQPQLMG
                     RTLYNIGLCKNSQSQYEDAITYFKRAIAVFEESNILPSLPQAYFLITQIHYKLGKMDKA
                     HEYHSKGMAYSQKAGDVIYLSEFEFLKSLYLSGPDEEAIQGFFDFLESKMLYADLEDFT
                     IDVAKYYHERKNFQKASAYFLKVEQVRQLIQGGVSLYEIEV"
     CDS             13749..13868
                     /locus_tag="ctg34_16"
                     /transl_table=11
                     /translation="MKLKSKLLLSCLALSTVFVATTIANAPTHQIEVAQRGMI"
     CDS             13966..14277
                     /locus_tag="ctg34_17"
                     /transl_table=11
                     /translation="MSLKSVRTHFTQWNRENDVTEFETSSATVEQAAETIGVSLSRIAK
                     SLSFRGEGDQVILIVAAGDAKIDNKKSRQTFGFKARMLSPNEVLEQTGHEIGGVCPIG"
ORIGIN
        1 cacaacaccg gcatgggctt cgctattgca ggttgagggg acaacgaaat gtgagtgaac
       61 aagttctcct cacagccgca tgccagaaca tgaagaagat tgccacatac ctagccaagc
      121 agggctaggc atgtgggagc gctttttctg catctgaaac ctgatgaata tctaaagaaa
      181 ctgtataaaa caaaaaagct tgtagaaaaa acgtcgtttt ctctacaagc taaggacaaa
      241 gtccgaagac tttgtccttt tgttcgtgat tacatttttt ccggagccga tacgccgatc
      301 agctgaagcg cattgttcag cgtaatttgc gttgccttca ttaaagccag gcgcgcgcgg
      361 cttttctctt cattttcagg gtcgatgact ttctctgcgt tgtagaagct gtgcagagca
      421 gaagccagat cataaatata gttagtgaca cggtgcggaa ttcgtttttc cgctgcttcc
      481 gccactgcct ctgggaagcc gccgatcgtt ttcagcagat cgtattcttt ttctgattga
      541 atatggctga aatcaagatc tgccgccggt ttaagcccct gctcttcccc ttggcgaagc
      601 atgctgcaaa tacgtgcatg cgcgtattgt gcataataca cagggttttc gttagatgtt
      661 gatacagcaa gatctaagtc aaaatccata tgggtgtctg cacttcgcat tgcaaagaag
      721 taacgcacgg catccaagcc gacttcttca atcaggtcac gcatcgttac ggctttaccg
      781 gtccgtttgc tcattttcat tttctcgccg tttttgtaaa ggtgaacgag ctgaatgatt
      841 tctacttcaa gcgttccttt ttcatacccc agcgcttcga ttgccgcttt catacgcggg
      901 atgtagccgt ggtgatcggc gccccaaacg ttgatcagct tatcaaagcc gcggtcaagc
      961 ttgtccttat gatacgcgat atcaggaagc aggtacgtgt acgtgccgtc cttcttgatc
     1021 aatacgcggt ctttatcatc gccaaacgtc gtggaacgga accaagtcgc gccgtcttct
     1081 tcatagacat ggccttttcc gcggagcgct tcaagcgcct tgtcgatttt tccattttgg
     1141 tacagtgaag tttctgaata ccacacatca aacggcacac ggaagttttc caagtccttg
     1201 cgaagctttt ccagctcgta tttcaggccg tattcacgga aaaacgcgag gcgttcactt
     1261 tcctcttcgt taacgaaacg gtcaccgtat tcctcagcga gacgctttcc gatcgcaatg
     1321 atatcctcgc cgcggtagcc atcctccggc atcggttttt ccaatccgag tgcttcgaag
     1381 taacggactt caacagagag cgccagattg ttgatttggt ttcccgcatc gttaatgtag
     1441 tattcgcggc ttacatcgta acccgctttt gaaagcacgt tgcacaagga atcgccgaca
     1501 gccgccccgc gcgcatgccc gaggtgaagg tctcccgtcg gattcgctga tacgaattct
     1561 acctgaactc gttcaccgtt tccgatgttc gtttccccgt atgcttcccc tgcttccagt
     1621 acagacggaa tcagctttgt taaatattga ttgttcatat agaaattgat aaaacccggg
     1681 ccggcgatat ccagtttttc aatcgaagcc tttcctttat caaaatgggc gacaatctct
     1741 tcagcgattt ggcgcggcgc tttttttgcc actcttgcca gctgcatcgc catattcgtt
     1801 gagtagtcgc cgtgtgtttt atctttcggt atttctaaaa caacattggg aatctggctt
     1861 tcttcagcca gtcccgcttt cagaacggcc gctttgattt cttctttcag cacgtccttc
     1921 atttgttccg caatgttcat gcgtgagttc ctccctcata cgtgatcgtc atattatgta
     1981 aatgctcctg ctcgtctccg acatgcatgt catatgcgat gctgatacgg cctttttctt
     2041 catcgagatc agattgaatc gattttgtgc ttgttttcag ctcaagctca ccaaatgaca
     2101 ttttatattt agcaattgtg gaagctccct ttacgaaacg ctgattcatt ttgacagcgc
     2161 ctgacctcat gaccaggact tcgccttcgc ttactttcac aatcgttttg actttgccta
     2221 agtcgtgttc ttcataataa gatagataca ctttattttg ttttacatag taaaatccgg
     2281 tggtgcggaa ttcgatgact tcttggtttc cgtcatcctc gatcacagac ttcacatgga
     2341 gtgttatcgg tgtctcttgc ttcattctga cacgtccttt tcatcattcc actttgactt
     2401 gaatagtata atcattcggt ttgtaaactt caactgcttc tatcttacca tcattgctca
     2461 tcagatttga agataaacct cataaaaagc atttccttat atagaagaga aaatcatatc
     2521 actaattacc tttagtaaat gttacatttt tccgaaatct atcatttcct tttcacattt
     2581 ttttcaaaat atatgtattg aattagtaat ttgatagttt taagataaaa gtacaacata
     2641 gatctgttag aaaaacaaaa aaaaagggag gattcaatta tgaaaaaagc tgtcattgta
     2701 gaaaacaaag gttgtgcaac atgctcgatc ggagccgctt gtctagtgga cggtcctatc
     2761 cctgattttg aaattgccgg tgcaacaggt ctattcggtc tatgggggta aggatctccc
     2821 aaaagggcat agtcattcta ctatgccctt tttaagtaaa ttacaatttt taactaaaat
     2881 ctacctcttg gatatacata cacaaccgtt tttcatttga atcatatgta taggggatgg
     2941 tattttgttt atagagcaga tgtttccatt tattaatgaa agtgtaagag ttcaccagct
     3001 tcctgagggc ggcgtgttag aaatcgacta cttgcgcgat aatgtctcca tttctgactt
     3061 tgagtatttg gatctcaaca aaacagctta cgagctctgc atgcgcatgg atggccaaaa
     3121 aacagctgag cagattttag ctgagcaatg tgcagtgtat gatgaatcac cggaagacca
     3181 taaagattgg tattacgaca tgctcaacat gctccagaac aagcaggtta tccagcttgg
     3241 aaaccgggcc atccgccata ccatcaccac gagcggaagc aatgaatttc cgatgcccct
     3301 gcacgccacc tttgaactga cgcaccgctg taatttgaaa tgcgcccact gttatttgga
     3361 aagctcgcct gaagcgctcg gcaccgtgtc gattgagcaa ttcaaaaaaa cggctgatat
     3421 gctgtttgat aacggtgtat tgacatgcga aatcacaggc ggagaaattt ttgtccatcc
     3481 aaacgccaat gagattcttg actatgtgtg taaaaagttc aaaaaagtcg ctgtcttaac
     3541 aaacggaaca ctcatgcgaa aagagagcct ggagcttttg aagacttaca agcaaaaaat
     3601 catcgtcggc atttctcttg atagtgtcaa ttccgaggtc catgactcct ttagagggag
     3661 aaaaggctct tttgcccaaa cttgtaaaac gataaaattg ttgagtgacc acggtatatt
     3721 tgtcagagtc gccatgtctg tcttcgaaaa aaacatgtgg gaaatccacg atatggccca
     3781 aaaggttcgg gatctcggag cgaaggcgtt ttcttacaat tgggttgacg atttcggaag
     3841 aggcagggat attatccatc caacgaaaga cgccgagcag caccgcaagt ttatggaata
     3901 cgagcaaaat gtgattgatg agtttaaaga tctgattccg attattccct atgagagaaa
     3961 acgcgcggca aattgcggcg ctggctggaa gtccattgtg atcagcccgt tcggcgaagt
     4021 acgtccttgc gccctctttc caaaggaatt ttcattggga aatatttttc atgattccta
     4081 tgaaagcatc tttaactccc ctctcgtcca taaactgtgg caagcgcagg cgccgcggtt
     4141 cagcgaacat tgcatgaaag acaaatgccc gttcagcggc tattgcggag gctgttactt
     4201 aaaagggctg aactctaaca aatatcaccg aaaaaacatt tgctcttggg cgaaaaatga
     4261 acaattagaa gacgtggtcc agcttattta ggagggaaac gatttgtcac cagcacaaag
     4321 aagaatttta ctgtatatcc tttcatttat ctttgtcatc ggcgcagtcg tctattttgt
     4381 caaaagcgat tatctgttta cgctgatttt cattgccatt gccattctgt tcggaatgcg
     4441 cgcgcggaag gctgactcgc gatgagcatt ttggatatac acgatgtatc cgtttggtat
     4501 gaacgggaca acgtcatctt agaacaagtg gatttacatt tagaaaaagg cgccgtttac
     4561 gggctgcttg gggtaaacgg cgccggaaaa acgacactga ttaatacgct gacaggcgtg
     4621 aaccgcaatt tcagcgggcg ctttacactg tgcggaattg aagcggaggc cggcatgccg
     4681 cagaaaacat cagatcagct gaagactcac cgttacttcg ccgccgatta tccgctgcta
     4741 tttacagaaa ttacggcgaa ggactatgtg tctttcgtcc attcgcttta tcaaaaggat
     4801 ttttcagagc agcagtttgc cagtttggcc gaggcctttc atttttcgaa atacatcaac
     4861 aggagaattt cggagctgtc cttggggaac aggcaaaagg ttgtattgat gacaggctta
     4921 ttgctgcgcg ctcccctatt tattttggat gagccgctcg tcggtttgga tgtggaatcg
     4981 atagaggttt tttatcagaa aacgcgcgag tactgtgaag caggcgggac cattttgttt
     5041 tcttctcatc tgctcgatgt cgtgcaaaga ttttgtgatt acgcggccat tcttcacaac
     5101 aaacagatcc aaaaggtcat tccgattgga gaggagaccg atctgcggcg ggaatttttc
     5161 gaggtgatcg gccatgaata acataatccc catcatgtct ttgctgttca aacagcttta
     5221 cagccggcaa gggaaaaagg acgccatccg cattgccgca ggccttgtca ttctggccgt
     5281 atttgaaatc gggctgatcc gccaggccgg cattgatgaa tcggtgttgc gcaaaacgta
     5341 tatcatactc gcgcttctct taatgaacgc atatatggtg tttctttctg tgacatctca
     5401 atggaaggaa tcttatatga aactgagctg cctgctgccg atttcttcac ggagcttttg
     5461 gctcgcccag agtgtcgttt tgtttgtcga tacctgtttg agaagaacgt tattcttttt
     5521 tattttaccg ctgttcttat ttggaaacgg aacgctgtca ggggcgcaaa cattgttttg
     5581 gctcggcagg ttttcgtttt ttaccgttta ctccattatt ttcggagttg tgctaagcaa
     5641 ccacttcgtc aaaaagaaga acttgatgtt tctgctgcat gcggcgatat tcgcctgtgt
     5701 atgtctcagc gccgctttga tgccggccgc cacgcttccg ctttgcgcgg tgcatatgct
     5761 gtgggcggtg gtcattgact ttcctgtctt tctgcaggcg cctccgcagc agagcaggat
     5821 gcattcattt atgcggcgat ctgagttttc gttttacaaa agagaatgga accgatttat
     5881 ctcttctaaa gcgatgctgt taaattacgc ggtaatggcg gcgttcagcg gcttcttttc
     5941 gttccagatg atgaataccg gcatcttcaa tcagcaagtg atttatatcg tgatttccgc
     6001 gcttctgctc atctgctcgc cgatcgccct tttgtactcg attgaaaaaa atgaccgcat
     6061 gctgctcatc acgcttccga tcaagcggaa aacgatgttt tgggcgaaat atcgctttta
     6121 ttcaggccta ttggcaggcg gatttctcct tgtcgtgatg attgtgggtt tcatcagcgg
     6181 ccgtccgatt tcagttctca cttttttgca gtgcattgag ttgctgctgg cgggagcttt
     6241 tatcaggtta actgcggata aaaaaaggcc cttcttcagc tggcagacgg agcagcagct
     6301 atggagcggt ttctcaaaat atcggtctta tctgttttgt cttcccctat tcttagccac
     6361 attagccggc accgctgtat ccttggcggt cattccgata gccggtctgg tcatagtcta
     6421 ttacctgcaa aaacaggatg gtggtttctt tgatacaagc aaaagagaac ggcttggaag
     6481 ttaacctgct gaagactcat caattttcaa ctatatcaat cgccgcgagc tttctgaaac
     6541 cgatcgaaag cgcggcggaa cctgaggaag aaacgattta tttttacggc gccgccgcat
     6601 acctgaagga gcaaatcatt gacgatttcg gttgtgctgc cggcagccgt ttcatgtact
     6661 cagcgaatct cttttttgat cagcagctga aaacctgcgg gacccgtttg attcacccat
     6721 tatataacgg gaatcttcat gttgacgccc tgatgaaaac ttttgcagac ttgtctttcc
     6781 cttcttctct ttcattcgaa gcagttgaaa aggccaggaa tgagctgctg ctgaaaatcg
     6841 aaaagaaatt cactgatccc ttctcctact cggcggcgcg cttggctgag gaggtcttcg
     6901 gaaacccgat gtacggcaca ggcatgtttg gccggaaaga caggataaag gcgattcatc
     6961 ctaaacggtt tcacgacgca acggacttta tcgttgattt agcgtcccag caaaaacagc
     7021 tgaacatatt gggacaagta caagcatgtg atgttcgggg acatgccccg caaacgtccg
     7081 ctgtaacgtc cgaaagaata cccgtaaacc ggcatgtttt tgaaacagag acacgcagcg
     7141 ctgcaggtcc ttccgtcttg acactcggat ttgactgcgg agagatgaaa gatgccagtg
     7201 attatatcaa aatacagcta atagacggat tactgggaaa gtacggccat tccgctttat
     7261 tcaagcactt cagagagaaa gatctggcag tctatcacgt tatcacccgt tacgatgtca
     7321 tgaacaattt gctgcttgtt tcaatatgta cagatcagct tcatgagata gacattcccc
     7381 cgcgcgtttt ggaagctgtc tcagcttttc atacagatga gcgggaacta gaacaggcaa
     7441 agcagttttt acgcaatgaa ttgctgctgc aattcgattc tcccgaaggt ctattggcct
     7501 atatggggat cctgcgccgc ttctcctgca cgaaagaagc cttgctggat ggcatctcag
     7561 cggttacatg ccgtgatgta ttgcaattca tagcgaccat caattatatc ggagctcatg
     7621 tagtaagggg atgaaaagat ggaaaagaaa gccttttttc aacagctgga tgaacgaacc
     7681 gatatcagat acacagacag cggactaaaa atattcagat tgaaattccc ccgcgcccac
     7741 ctgcggctgt gcaatgtaaa aatcgatttt ggaagccggg atgtatgtat acgggcagaa
     7801 tccggtgata cactgcttcc gtatggcaca gcgcattttt tagagcatct tctcttctgg
     7861 cataacggcc gcaatctgta cagtgatttt tttgcgcatg gcgcgctttt aaacgcattc
     7921 actacctaca ccgataccaa tttcatgttt acctcattac cggatcggct cagacaaacg
     7981 atccccatcc tgcttgatgc tttatggaac cactcatttg acaagaagat tgtcgctcag
     8041 gaaaaagctg tgattacaag cgaaattcaa acagcacacc ttaaccatca gctctcatat
     8101 cattatcagc tgatcagcat gctttctccc tcctcaccag ctgccgtttt ccccgcaggc
     8161 agaatcgaag atattgaggc gcttgacatc agtgatttac aaaaagccta taaggctgcc
     8221 taccaaaccc atcggatgac gctgtttttg attgggggct cagaaaatac agaaacgctt
     8281 ttgcctcctc acctccagct ggaaaagcgt ccagattatc atactgaaag aaaaatcatc
     8341 ccggcatgcc ctccagccct ctcacaaaaa atgatgctgg gtgatgagga gcggatggaa
     8401 gatacatgga ccggattaca gatcggcgca cttcccgggc aaaacgatct gttgacgatc
     8461 aaactttatt gggatatcgc ggctcgtatt ctatttcaat tagattcacc gttttttcaa
     8521 gagattcagc aaacgtaccg cctggaaatc gatcgtttgt cagccgagac ttatatctat
     8581 gaggatggcg gtttcttgat ccttcacagt caagggaccc attcttcagc ttatatcgat
     8641 gtggcttcat actatgtcac acagaagaaa gaacaggctg ccgcctggct tcaatacggc
     8701 aaggactctt tgacagacgc gatcatttat gacagcgatt atgtgcgtaa atgcttcgag
     8761 tgggcagccg agtgtgacag gtgcgattgc tcgtttcttg acatgtacca catcattcaa
     8821 gatatggatg cgcaggtttt cttgtctctc attgatgcaa tggcatcttc taacaaagcg
     8881 atcatttaca tttctcagaa agaggcgatc agacaatgaa aaaaaacact gtctttaccc
     8941 ttttattgct gcttataggt atggcggctt attccttcgg ctgggttcag gccgttgccg
     9001 aagccgccgc ccactatata cagatgatca acaatgatgc tgtacggctc ggactgctgg
     9061 cttgtaccgc tgccctcctg atgctgcctg cttttctcta tcttcactat gtcacccaat
     9121 ctgtgaaaaa catgacagca gcttttcaga aactcacaca gtctcatcaa agctgctgtg
     9181 actttcagca acacaacttg tgcagccgat atgcagaaga cgtcaaatcg ctgcgtgacg
     9241 gctataaaaa cgtccgccaa acatacgtga tggctgccgt gttgtgccaa gtcatcatat
     9301 tcggctgcat gttcgaaatc gttaaagccg tccctttccg ccttcacacg ccccctgccc
     9361 tttcaatggg acttgcgatg ctactgatcc tgtatttatt gttttgcatg cgaacgtatt
     9421 tgcggcagct tttccggcac ggcagcctgt tcagaaaagt gtttgcggga gcgctggcag
     9481 cagccgggat ttggtggatg ctcagtttca ctataagtga actgctgttt ctgattatcc
     9541 tggctgccat ccagcaaatc ggatcattta tttataagcg attctcttat cgcagcaccg
     9601 cttctcttga tctataaaat agctacatca caatcgcaga cgggcccgcg ccaaccgaaa
     9661 tcaccttcac ggctgtataa tcacttgtgc ggtacacggt cacagcattg tcgttgggct
     9721 gtgccgcata aatatactgt ttgtccggcg ttacggcgag gtcaaaagcg ccggggagag
     9781 acacgtttgc aatgatcctc tgtctggccg tattaactac atataagtta ttaataagaa
     9841 acggttcact atatggctct agaaaataag ctctagtgct atcgagagaa aatacaatcg
     9901 tcctcagcgt ttcaaataaa cggctgaagt cccctcccct gcttaatgga gacaaactaa
     9961 tctccgttac acctttcggc cacagctcac cattcaacac gtacgcaaaa tttccagcgt
    10021 aaggagttgc aattaaactg ggaaattcaa atgtatctat gatactttct accaactgcc
    10081 cagtatttac atcatattta tcaaccgacc aactgcttcc attagcggta tagacatact
    10141 gtccattcgg atcaagagca aagtctaaag cgccgggtat cgcgattaca tcaattactg
    10201 attgattggc cgtgtcaatc atatatatag atccggcggc catcacgtag gcgtactcat
    10261 ctgttggatc aaattcgatc tttctcggtc ctcctccaac agtaatggta tttatgatgg
    10321 ttaatgtttt attatcaatc actgagacaa ggttggtatt cccatggagg acatacgtga
    10381 atgctttatc gaaagtaacg cctagattag ttggcacagc agaaaacagg attgttttta
    10441 caacagtgtt taaatctgca tcaatgaccg aaaccgtgct gtctccagta ttggcagtaa
    10501 acacatacga ttgagggtct ggcgatggcg gcaaaacaag tgtcccggcc accgtgagcg
    10561 gactgccgta gaaaggcggc acgatgagaa gatcttccac tgtcatctga ctaaaatcag
    10621 gacagcggtc agactgtgct gcataataaa caacttgatc aatctcttca gtatgaatca
    10681 cagaaaccgc cccgtctcct tgtccatatt gatttcgcac aggcgacaca ctgacaagaa
    10741 gcataatggt cccttgtact ctcacagcat atcgaacacc aatatcttct gtttccggcc
    10801 cagtctggat taagcaaggc tcactgatac aggacacatt gtctgtactc catgtaacag
    10861 ccgctgacgc ttcggccgaa tcaaccttga agccctcagg gatatctatc ggcacttgaa
    10921 acggcgcttc tcggctaatt tcctcatcac aaaaacagaa acaattttcc tgtaaagcag
    10981 aaagatccat tctttttcat gatttcacgt ccttttagaa atgcacaaca tgcagcggtt
    11041 aaatcgtaat ggcacccggt gaaaccccaa gagatatcac agtttcctca gaataatcat
    11101 ctgtgttgta aacaatgatg ctctgctcta taaaacgagt tgcatacaga aaatcgccat
    11161 tcggggtaaa cgcatagtct gttgctgatt gcggaagatt tccaattaca cctgctccat
    11221 tcggactgac agaatataaa ttgccagtga agctgtcatg taaatacacc tctgatccac
    11281 tcgtaaacat tacatatagc ccgtcaggct ccagctcttg ggtatccctg atcgtaaacg
    11341 tatttaaatc aataaccgtc aaataattga ataagaattc ttgttctaat acatacgcat
    11401 accgctccgt agaatctgtt tctatggatg atacgataag ctctcgttca atcgttcctg
    11461 tgacttcacc ggtagttagg tccacttttt gcactatacc aaaatttaga acataggcga
    11521 ataacccatt ggggtcaatt gcaatatcaa aaccttctat atagacctct caacagtcaa
    11581 cgtatcaatt ccaatcacat aaatggcagt accggtgaaa acataagcaa actcatgatt
    11641 agggataaat ctaatcaatc gaggcggctg atccagcaat atagttgctg tcactgttaa
    11701 tgtgtcataa tcgatgacag aaatcacatt attgttggga tgtaagacaa acacagcgct
    11761 tttatctggc gtaatttcaa tacctgccgg attgtacgga agagcaatcg ttgtcacaac
    11821 agtatgggtg tttgtatcaa tcacagaaac tgattgatca tttggattcg ctgtaaacgc
    11881 gtagacgggt tccggctccg gtacaagcac aatcgtcccc gtcaccgata aaggactgcc
    11941 gtaaaacggc ggaacaacaa caaggttctc aatcgtgatg ttactgatat ccgggcaatc
    12001 atccggttca tcggaataat agacgacttg atcgatttct gcattgtgaa tgacggaaac
    12061 agccccatcc ccttgtccat attgatttcg cacaggtgag acactgacga gcagcgtaac
    12121 ggttccctgc agacgcactg caaattgaac accgacctca tcaggctctg gccccgtttg
    12181 aattaagcaa cggtcactga cacaagaaag gctgtctgca ttccacgtca cgtttgcaac
    12241 agcttcagcc ggatcaacga caaatccttc aggtaattca atcggcgctt gaaacatggc
    12301 ttctcggctt gcttctccct cacaaaaaca taagcactct tcttgttctg ctcctgcttt
    12361 ttctttaaag gaaagcttgt tttttctcat tccttcactt ccttttcaga catacactgc
    12421 tcacgcagat ataacagaat atggaagagt aacgtgtttg cttgtacaaa ttactgaggg
    12481 taaaagcttc tttttgaaaa tatatctcca aacatgcggt gtaacgaaag aaaaaattgc
    12541 ggtttttttg cgcttctcac aagaatgttg atgataaaat atgacatata tagaattatg
    12601 aagggaggga tttgcaaacg tgacaggtgt catatcttct tcttccatcg gagaaaagat
    12661 taacgaatgg tatatgtaca tacgccgatt cagcataccc gatgcagaat atttgcgacg
    12721 agaaatcaag caagagctgg atcaaatgga agaagatcaa gaccttcatt tgtactattc
    12781 actgatggag tttcggcaca acctgatgct tgagtacctt gaaccgttag aaaaaatgag
    12841 gattgaggaa cagccgagac tgtctgatct gctgcttgag attgataaaa aacaggctcg
    12901 tttaacaggt ctgcttgagt actattttaa tttcttcaga ggcatgtatg agctggatca
    12961 gcgggaatat ctgtcggcta ttaaattttt caaaaaggcc gaaagcaagc tgatattcgt
    13021 taaggatcgg atagagaaag ctgagttttt ctttaagatg tctgaatctt attactatat
    13081 gaaacaaacg tatttttcaa tggactatgc acggcaagca tatgaaatat acaaagaaaa
    13141 tgaagcttat aatataagat tgctgcagtg tcattcttta tttgccacca attttttaga
    13201 tttaaaacag tatgaggatg ccgtctcaca ttttcaaaaa gcttattcta tggcagaagc
    13261 tgaaaagcag ccccaattaa tgggaagaac tttgtacaat atcgggcttt gtaaaaacag
    13321 ccaaagccaa tatgaggatg ccataacata tttcaaaaga gcaatagctg tttttgaaga
    13381 atcaaatatt cttccttcct tacctcaagc gtatttttta attacacaga tccattataa
    13441 attaggaaaa atggataaag ctcatgaata tcatagtaag ggaatggctt attcacaaaa
    13501 ggccggagat gtaatatatt tatcagagtt tgaatttttg aaatctttat acttatcagg
    13561 cccggatgaa gaagcaattc aaggattttt tgattttctc gaaagtaaaa tgttgtatgc
    13621 tgatcttgaa gatttcacta ttgatgtggc aaaatattat catgaacgta aaaattttca
    13681 aaaagcttct gcttattttt tgaaggtgga acaagtaagg caacttattc aaggaggagt
    13741 gagtttgtat gaaattgaag tctaaactat tactctcttg tctggctcta agcactgtgt
    13801 tcgtggcaac aactattgca aatgcaccta cacaccaaat tgaagttgca caacgaggaa
    13861 tgatttaacc gccgtccatc ggcggttttt ttgtcccctc tttacccagt ctcccaatcc
    13921 attctatgat tttttcaata atcttaaaaa tagtggaaat gcagcatgtc tctaaaaagt
    13981 gtgagaaccc actttactca atggaatcga gaaaatgatg tgacggagtt cgaaacgtcg
    14041 agtgcgacag ttgaacaggc agctgagaca atcggcgtaa gcctgtctag aatcgccaag
    14101 tccctgtcct tcagagggga aggagatcag gtgattctga ttgtggcagc cggcgatgcc
    14161 aagatcgaca acaaaaagtc caggcaaaca tttggcttta aagcaagaat gctctctcct
    14221 aatgaggtac tggagcagac aggccatgaa attggaggag tttgcccaat tggatagact
    14281 catgatcctg a
//
