LOCUS       gnlProkkaPGHHMJKG_23   14276 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PGHHMJKG_23.
ACCESSION   gnlProkkaPGHHMJKG_23
VERSION     gnlProkkaPGHHMJKG_23
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 19:10:26
            Original ID  :: gnl|Prokka|PGHHMJKG_23
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14276
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14276
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2664:4276]"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2665..4276
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     cand_cluster    1..14276
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14276
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="sactipeptide"
                     /region_number="1"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     CDS             2..142
                     /locus_tag="ctg23_1"
                     /transl_table=11
                     /translation="MPLIQEAGKTNCDPTRTPHSRMPEHEENCHIPSQAGLGMWERFFC
                     I"
     CDS             118..291
                     /locus_tag="ctg23_2"
                     /transl_table=11
                     /translation="MGALFLHLKPDEYLKKLYKTKKLVEKTSFSLQAKDKARRLCPFDR
                     DYIFSGADTPIS"
     CDS             complement(255..1925)
                     /locus_tag="ctg23_3"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLETPKDKTHGD
                     YSTNMAMQLARVAKKAPRQIAEEIVAHFDKGKASIEKLDIAGPGFINFYMNNQYLTKLI
                     PSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRF
                     VNEEESERLAFFREYGLKYELEKLRKDLENFRVPFDVWYSETSLYQNGKIDKALEALRE
                     KGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWG
                     ADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKP
                     AADLDFSHIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     CDS             complement(1922..2350)
                     /locus_tag="ctg23_4"
                     /transl_table=11
                     /translation="MKQETPITLHVKSVIEDDGNQEVIEFRTTGFYYVKQNKVYLSYYE
                     EHDLGKVKTIVKVSEGEVLVMRSGAVKMNQRFVKGASTIAKYKMSFGELELKTSTKSIQ
                     SDLDEEKGRISIAYDMHVGDEQEHLHNMTITYEGGTHA"
     CDS             2665..2796
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_functions="biosynthetic-additional (sactipeptides)
                     predicted sactipeptide"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_5"
                     /sec_met_domain="Subtilosin_A (E-value: 1e-30, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       2665..2694
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="ctg23_5_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       2695..2796
                     /prepeptide="core"
                     /locus_tag="ctg23_5_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="27.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[2664:2694](+)"
     CDS             complement(3152..3463)
                     /locus_tag="ctg23_6"
                     /transl_table=11
                     /translation="MDKNFSACDFACQYTVIKQHISRFFELLNRHGAERFRRAFQITVG
                     AFQITAVRQFKGGVQGHRKFIASARGDGMADGPVSKLDNLLVLEHVEHVVIPIFMVFR"
     CDS             3719..4276
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_7"
                     /sec_met_domain="subtilosin (E-value: 9.2e-140, bitscore:
                     457.4, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 9.7e-13, bitscore:
                     40.0, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 2.5e-12, bitscore: 38.8,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVFEKNMWEIHDMAQKVRDLGAKAFSYNWVDDFGRGRDIIHPTK
                     DAEQHRKFMEYEQNVIDEFKDLIPIIPYERKRAANCGAGWKSIVISPFGEVRPCALFPK
                     EFSLGNIFHDSYESIFNSPLVHKLWQAQAPRFSEHCMKDKCPFSGYCGGCYLKGLNSNK
                     YHRKNICSWAKNEQLEDVVQLI"
     CDS             4289..4450
                     /locus_tag="ctg23_8"
                     /transl_table=11
                     /translation="MSPAQRRILLYILSFIFVIGAVVYFVKSDYLFTLIFIAIAILFGM
                     RARKADSR"
     CDS             4447..5166
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 125.6; E-value:
                     4.3e-38)"
                     /gene_kind="transport"
                     /locus_tag="ctg23_9"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYERDNVILEQVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGRFTLCGIEAEAGMPQKTSDQQKTHRYFAADYPLLFTEITAKDYVS
                     FVHSLYQKDFSEQQFASLAEAFHFSKYINRRISELSLGNRQKVVLMTGLLLRAPLFILD
                     EPLVGLDVESIEVFYQKTREYCEAGGTILFSSHLLDVVQRFCDYAAILHNKQIQKVIPI
                     GEETDLRREFFEVIGHE"
     CDS             5159..6469
                     /locus_tag="ctg23_10"
                     /transl_table=11
                     /translation="MNNIIPIMSLLFKQLYSRQGKKDAIRIAAGLVILAVFEIGLIRQA
                     GIDESVLRKTYIILALLLMNAYMVFLSVTSQWKESYMKLSCLLPISSRSFWLAQSVVLF
                     VDTCLRRTLFFFILPLFLFGNGTLSGAQTLFWLGRFSFFTVYSIIFGVVLSNHFVKKKN
                     LMFLLHAAIFACVCLSAALMPAATLPLCAVHMLWAVVIDFPVFLQAPPQQSRMHSFMRR
                     SEFSFYKREWNRFISSKAMLLNYAVMAAFSGFFSFQMMNTGIFNQQVIYIVISALLLIC
                     SPIALLYSIEKNDRMLLITLPIKGKTMFWAKYRFYSGLLAGEFLLVVMIVGFISGRPIS
                     VLTFLQCIELLLAGAFIRLTADEKRPFFSWQTEQQLWSGFSKYRSYLFCLPLFLATLAG
                     TAVSLAVIPIAGLVIVYYLQKQDGGFFDTSKRERLGS"
     CDS             6435..7619
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_11"
                     /sec_met_domain="Peptidase_M16_C (E-value: 6e-07, bitscore:
                     21.2, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQAKENGLEVNLLKTHQFSTISIAASFLKPIESAAEPEEETIYF
                     YGAAAYLKEQIIDDFGCAAGSRFMYSANLFFDQQLKTCGTRLIHPLYNGNLHVDALMKT
                     FADLSFPSSLSFEAVEKARNELLLKIEKKFTDPFSYSAARLAEEVFGNPMYGTGMFGRK
                     DRIKAIHPKRFHDATDFIVDLVSQQKQLNILGQVQACDVRGHAPQTSAVTSERIPVNRH
                     VFETETRSAAGPSVLTLGFDCGEMKDASDYIKIQLIDGLLGKYGHSALFKHFREKDLAV
                     YHVITRYDVMNNLLLVSICTDQLHEIDIPPRVLEAVSAFHTDERELEQAKQFLRNELLL
                     QFDSPEGLLAYMGILRRFSCTKEALLDGISAVTCRDVLQFIATINYIGAHVVRG"
     CDS             7624..8904
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_12"
                     /sec_met_domain="Peptidase_M16 (E-value: 2.8e-15, bitscore:
                     48.2, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKAFFQQLDERTDIRYTDSGLKIFRLKFPRAHLRLCNVKIDFG
                     SRDVCIRAESGDTLLPYGTAHFLEHLLFWHNGRNLYSDFFAHGALLNAFTTYTDTNFMF
                     TSLPDRLRQTIPILLDALWNHSFDKKIVAQEKAVITSEIQTAHLNHQLSYHYQLISMLS
                     PSSPAAVFPAGRIEDIEALDISDLQKAYKAAYQTHRMTLFLIGGSENTETLLPPHLQLE
                     KRPDYHAERKIIPACPPALSQKMMLGDEERMEDTWTGLQIGALPGQNDLLTIKLYWDIA
                     ARILFQLDSPFFQEIQQTYRLEIDRLSAETYIYEDGGFLILHSQGTHSSAYIDVASYYV
                     TQKKEQAAAWLQYGKDSLTDAIIYDSDYVRKCFEWAAECDRCDCSFLDMYHIIQDMDAQ
                     VFLSLIDAMASSNKAIIHVSQKEAIRQ"
     CDS             8901..9602
                     /locus_tag="ctg23_13"
                     /transl_table=11
                     /translation="MKKNTVFTLLLLLIGMAAYSFGWVQAVAEAAAHYIQMINNDAVRL
                     GLLACTAALLMLPAFLYLHYVTQSVKNMTAAFQKLTQSHQSCCDFQQHNLCSRYAEDVK
                     SLRDGYKNVRQTYVMAAVLCQVIIFGCMFEIVKAVPFRLHTPPALSMGLAMLLILYLLF
                     CMRTYLRQLFRHGSLFRKVFAGVLAAAGIWWMLSFTISELLFLIILAAIQQIRSFIYKR
                     FSYRSTASLDL"
     CDS             complement(9608..10984)
                     /locus_tag="ctg23_14"
                     /transl_table=11
                     /translation="MKKNDLSALQENCFCFCDEEISREAPFQVPIDIPKGFKVDSAEAS
                     AAVTWSTDNLSCVSEPCLIQTGPETEDIGVRYAVRVQGTIMLLVSVSPVRNQYGQGDGA
                     VSVIHTEEIDQVVYYAAQSDRCPDFSQMTVEDLLIVPPFYGSPLTVAGTLVLPPSPDPQ
                     SYVFTANTGDSTVSVIDADLNTVVKTILFSAVPTNLGVTFDKAFTYVLHGNTNLVSVID
                     NKTLTIINTITVGGGPRKIEFDPTDEYAYVMAAGSIYMIDTANQSVIDVIAIPGALDFA
                     LDPNGQYVYTANGSSWSVDKYDVNTGQLVESIIDSFEFPSLIATPYAGNFAYVLNGELW
                     PKGVTEISLSPLSRGGDFNRLFETLRTIVFSLDSTRAYFLEPYSEPFLINNLYVVNTAR
                     QRIIANVPLPGAFDPAVTPDKQYIYAAQPNDNAVTVYRTSDYTAVKVIPVGAGPSAIVM
                     "
     CDS             complement(11023..11508)
                     /locus_tag="ctg23_15"
                     /transl_table=11
                     /translation="MFAYVLNFGLVQKVDLSTGEVTGTIERELIVSSIETDSPERYAYV
                     LEQEFLFNYLTVIDLNTFTISNTQELEPDGQYRMFTSGTGVYLYDDFTGNLYSVSPNGA
                     GVIGNLPQSATDYAFTPNGDFLYATRFIEQSIIVYNTDDYSEETVISLGVSPGAITI"
     CDS             complement(11541..12374)
                     /locus_tag="ctg23_16"
                     /transl_table=11
                     /translation="MRKNKLSFKEKAGAEQEECLCFCEGEASREAMFQAPIELPEGFVV
                     DPAEAVANVTWNADSLSCVSDRCLIQTGPEPDEVGVQFAVRLQGTVTLLVSVSPVRNQY
                     GQGDGAVSVIHNAEIDQVVYYSDEPDDCPDISNITIENLVVVPPFYGSPLSVTGTIVLV
                     PEPEPVYAFTANPNDQSVSVIDTNTHTVVTTIALPYNPAGIEITPDKSAVFVLHPNNNV
                     ISVIDYDTLTVTATILLDQPPRLIRFIPNHEFAYVFTGTAIYVIGIDTLTVERSI"
     CDS             12604..13749
                     /locus_tag="ctg23_17"
                     /transl_table=11
                     /translation="MTGVISSSSIGEKINEWYMYIRRFSIPDAEYLRREIKQELDQMEE
                     DQDLHLYYSLMEFRHNLMLEYLEPLEKMRIEEQPRLSDLLLEIDKKQARLTGLLEYYFN
                     FFRGMYELDQREYLSAIKFFKKAESKLIFVKDRIEKAEFFFKMSESYYYMKQTYFSMDY
                     ARQAYEIYKENEAYNIRLLQCHSLFATNFLDLKQYEDAVSHFQKAYSMAEAEKQPQLMG
                     RTLYNIGLCKNSQSQYEDAITYFKRAIAVFEESNILPSLPQAYFLITQIHYKLGKMDKA
                     HEYHSKGMAYSQKAGDVIYLSEFEFLKSLYLSGPDEEAIQGFFDFLESKMLYADLEDFT
                     IDVAKYYHERKNFQKASAYFLKVEQVRQLIQGGVSLYEIEV"
     CDS             13733..13852
                     /locus_tag="ctg23_18"
                     /transl_table=11
                     /translation="MKLKSKLLLSCLALSTVFVATTIANAPTHQIEVAQRGMI"
     CDS             13950..14261
                     /locus_tag="ctg23_19"
                     /transl_table=11
                     /translation="MSLKSVRTHFTQWNRENDVTEFETSSATVEQAAETIGVSLSRIAK
                     SLSFRGEGDQVILIVAAGDAKIDNKKSRQTFGFKARMLSPNEVLEQTGHEIGGVCPIG"
ORIGIN
        1 gtctccgcta atccaggagg ccgggaaaac caactgtgat ccaacaagga ctcctcacag
       61 ccgcatgcca gaacatgaag aaaattgcca catacctagc caagcagggc taggcatgtg
      121 ggagcgcttt ttctgcatct gaaacctgat gaatatctaa agaaactgta taaaacaaaa
      181 aagcttgtag aaaaaacgtc gttttctcta caagctaagg acaaagcccg aagactttgt
      241 ccttttgatc gtgattacat tttttccgga gccgatacgc cgatcagctg aagcgcattg
      301 ttcagcgtaa tttgcgttgc cttcattaaa gccaggcgcg cacggctttt ctcttcattt
      361 tcagggtcga tgactttctc tgcgttgtag aagctgtgca gagcagaggc cagatcataa
      421 atatagtttg tgacacggtg cggaattcgt ttttccgctg cttccgccac tgcctctggg
      481 aagccgccga tcgttttcag cagatcgtat tctttttctg attgaatatg gctgaaatca
      541 agatccgccg ccggtttaag tccctgctct tccccttggc gaagcatgct gcagattcgg
      601 gcatgtgcat attgtgcata atacacaggg ttttcgttag atgttgatac agcaagatct
      661 aagtcaaaat ccatatgggt gtccgcactt cgcatcgcaa agaagtaacg aacggcatcc
      721 aagccgactt cttcaatcag gtcacgcatc gttacggctt taccggtccg tttgctcatt
      781 ttcattttct cgccgttttt gtaaaggtga acgagctgaa tgatttctac ttcaagcgtt
      841 cctttttcat agcccagcgc ttcgattgcc gctttcatac gcgggatgta gccgtggtga
      901 tcggcgcccc aaacgttgat cagcttatca aagccgcggt caagcttgtc cttatgatac
      961 gcgatatcag gaagcaggta cgtgtacgtg ccgtccttct tgatcaatac gcggtcttta
     1021 tcatcgccaa acgtcgtgga acggaaccaa gtcgcgccgt cttcttcata gacatggcct
     1081 ttttcgcgga gcgcttcaag cgccttgtcg atttttccat tttggtacag tgaagtttct
     1141 gaataccaca catcaaacgg cacacggaag ttttccaagt ccttgcgaag cttttccagc
     1201 tcatatttca ggccgtattc acggaaaaac gcgaggcgtt cactttcttc ttcgttaacg
     1261 aaacgatcac cgtattcctc agcgagacgc tttccgatcg caatgatatc ctcgccgcgg
     1321 tagccatcct ccggcatcgg tttttccaat ccgagtgctt caaagtaacg gacttcaaca
     1381 gaaagcgcca gattgttgat ttggttaccc gcatcgttaa tgtagtattc gcggcttaca
     1441 tcgtaacccg cttttgaaag cacgttgcac aaggaatcgc cgacagccgc cccgcgcgca
     1501 tgcccgaggt gaaggtctcc cgtcggattc gctgatacga attctacctg aactcgttca
     1561 ccgtttccga tgttcgtttc cccgtatgct tcccctgctt ccagtacaga cggaatcagc
     1621 tttgttaaat attgattgtt catatagaaa ttgataaaac ccgggccggc gatatccagt
     1681 ttttcaatcg aagcctttcc tttatcaaaa tgggcgacaa tctcttcagc gatttggcgc
     1741 ggcgcttttt ttgccactct tgccagctgc atcgccatat tcgttgagta gtcgccgtgt
     1801 gttttatctt tcggtgtttc taaaacaaca ttgggaatct ggctttcttc agccagtccc
     1861 gctttcagaa cggccgcttt gatttcttct ttcagcacgt ccttcatttg ttccgcaatg
     1921 ttcatgcgtg agttcctccc tcatacgtga tcgtcatatt atgtaaatgc tcctgctcgt
     1981 ctccgacatg catgtcatat gcgatgctga tacggccttt ttcttcatcg agatcagatt
     2041 gaatcgattt tgtgcttgtt ttcagctcaa gctcaccaaa tgacatttta tatttagcaa
     2101 ttgtggaagc tccctttacg aaacgctgat tcattttgac agcgcctgac ctcatgacca
     2161 ggacttcgcc ttcgcttact ttcacaatcg ttttgacttt gcctaagtcg tgttcttcat
     2221 aataagatag atacacttta ttttgtttta catagtaaaa tccggtggtg cggaattcga
     2281 tgacttcttg gtttccgtca tcctcgatca cagacttcac atggagtgtt atcggtgtct
     2341 cttgcttcat tctgacacgt ccttttcatc attccacttt gacttgaata gtataatcat
     2401 tcggtttgta aacttcaact gcttctatct taccatcatt gctcatcaga tttgaagata
     2461 aacctcataa aaagcatttc cttatataga agagaaaatc atatcactaa ttacctttag
     2521 taaatgttac atttttccga aatctatcat ttccttttca catttttttc aaaatatatg
     2581 tattgaatta gtaatttgat agttttaaga taaaagtaca acatagatct gttagaaaaa
     2641 caaaaaaaaa gggaggattc aattatgaaa aaagctgtca ttgtagaaaa caaaggttgt
     2701 gcaacatgct cgatcggagc cgcttgtcta gtggacggtc ctatccctga ttttgaaatt
     2761 gccggtgcaa caggtctatt cggtctatgg gggtaaggat ctcccaaaag ggcatagtca
     2821 ttctactatg ccctttttaa gtaaattaca atttttaact aaaatctacc tcttggatat
     2881 acatacacaa ccgtttttca tttgaatcat atgtataggg gatggtattt tgtttataga
     2941 gcagatgttt ccatttatta atgaaagtgt aagagttcac cagcttcctg agggcggcgt
     3001 gttagaaatc gactacttgc gcgataatgt ctccatttct gactttgagt atttggatct
     3061 caacaaaaca gcttacgagc tctgcatgcg catggatggc caaaaaacag ctgagcagat
     3121 tttagctgag caatgtgcag tgtatgatga atcaccggaa gaccataaag attggtatta
     3181 cgacatgctc aacatgctcc agaacaagca ggttatccag cttggaaacc gggccatccg
     3241 ccataccatc accacgagcg gaagcaatga atttccgatg cccctgcacg ccacctttga
     3301 actgacgcac cgctgtaatt tgaaatgcgc ccactgttat ttggaaagct cgcctgaagc
     3361 gctcggcacc gtgtcgattg agcaattcaa aaaaacggct gatatgctgt ttgataacgg
     3421 tgtattgaca tgcgaaatca caggcggaga aatttttgtc catccaaacg ccaatgagat
     3481 tcttgactat gtgtgtaaaa agttcaaaaa agtcgctgtc ttaacaaacg gaacactcat
     3541 gcgaaaagag agcctggagc ttttgaagac ttacaagcaa aaaatcatcg tcggcatttc
     3601 tcttgatagt gtcaattccg aggtccatga ctcctttaga gggagaaaag gctcttttgc
     3661 ccaaacttgt aaaacgataa aattgttgag tgaccacggt atatttgtca gagtcgccat
     3721 gtctgtcttc gaaaaaaaca tgtgggaaat ccacgatatg gcccaaaagg ttcgggatct
     3781 cggagcgaag gcgttttctt acaattgggt tgacgatttc ggaagaggca gggatattat
     3841 ccatccaacg aaagacgccg agcagcaccg caagtttatg gaatacgagc aaaatgtgat
     3901 tgatgagttt aaagatctga ttccgattat tccctatgag agaaaacgcg cggcaaattg
     3961 cggcgctggc tggaagtcca ttgtgatcag cccgttcggc gaagtacgtc cttgcgccct
     4021 ctttccaaag gaattttcat tgggaaatat ttttcatgat tcctatgaaa gcatctttaa
     4081 ctcccctctc gtccataaac tgtggcaagc gcaggcgccg cggttcagcg aacattgcat
     4141 gaaagacaaa tgcccgttca gcggctattg cggaggctgt tacttaaaag ggctgaactc
     4201 taacaaatat caccgaaaaa acatttgctc ttgggcgaaa aatgaacaat tagaagacgt
     4261 ggtccagctt atttaggagg gaaacgattt gtcaccagca caaagaagaa ttttactgta
     4321 tatcctttca tttatctttg tcatcggcgc agtcgtctat tttgtcaaaa gcgattatct
     4381 gtttacgctg attttcattg ccattgccat tctgttcgga atgcgcgcgc ggaaggctga
     4441 ctcgcgatga gcattttgga tatacacgat gtatccgttt ggtatgaacg ggacaacgtc
     4501 atcttagaac aagtggattt acatttagaa aaaggcgccg tttacgggct gcttggggta
     4561 aacggcgccg gaaaaacgac actgattaat acgctgacag gcgtgaaccg caatttcagc
     4621 gggcgcttta cactgtgcgg aattgaagcg gaggccggca tgccgcagaa aacatcagat
     4681 cagcagaaga ctcaccgtta cttcgccgcc gattatccgc tgctatttac agaaattacg
     4741 gcgaaggact atgtgtcttt cgtccattcg ctttatcaaa aggatttttc agagcagcag
     4801 tttgccagtt tggccgaggc ctttcatttt tcgaaataca tcaacaggag aatttcggag
     4861 ctgtccttgg ggaacaggca aaaggttgta ttgatgacag gcttattgct gcgcgctccc
     4921 ctatttattt tggatgagcc gctcgtcggt ttggatgtgg aatcgataga ggttttttat
     4981 cagaaaacgc gcgagtactg tgaagcaggc gggaccattt tgttttcttc tcatctgctc
     5041 gatgtcgtgc aaagattttg tgattacgcg gccattcttc acaacaaaca gatccaaaag
     5101 gtcattccga ttggagagga gaccgatctg cggcgggaat ttttcgaggt gatcggccat
     5161 gaataacata atccccatca tgtctttgct gttcaaacag ctttacagcc ggcaagggaa
     5221 aaaggacgcc atccgcattg ccgcaggcct tgtcattctg gccgtatttg aaatcgggct
     5281 gatccgccag gccggcattg atgaatcggt gttgcgcaaa acgtatatca tactcgcgct
     5341 tctcttaatg aacgcatata tggtgtttct ttctgtgaca tctcaatgga aggaatctta
     5401 tatgaaactg agctgcctgc tgccgatttc ttcacggagc ttttggctcg cccagagtgt
     5461 cgttttgttt gtcgatacct gtttgagaag aacgttattc ttttttattt taccgctgtt
     5521 cttatttgga aacggaacgc tgtcaggggc gcaaacattg ttttggctcg gcaggttttc
     5581 gttttttacc gtttactcca ttattttcgg agttgtgcta agcaaccact tcgtcaaaaa
     5641 gaagaacttg atgtttctgc tgcatgcggc gatattcgcc tgtgtatgtc tcagcgccgc
     5701 tttgatgccg gccgccacgc ttccgctttg cgcggtgcat atgctgtggg cggtggtcat
     5761 tgactttcct gtctttctgc aggcgcctcc gcagcagagc aggatgcatt catttatgcg
     5821 gcgatctgag ttttcgtttt acaaaagaga atggaaccga tttatctctt ctaaagcgat
     5881 gctgttaaat tacgcggtaa tggcggcgtt cagcggcttc ttttcgttcc agatgatgaa
     5941 taccggcatc ttcaatcagc aagtgattta tatcgtgatt tccgcgcttc tgctcatctg
     6001 ctcgccgatc gcccttttgt actcgattga aaaaaatgac cggatgctgc tcatcacgct
     6061 tccgatcaag gggaaaacga tgttttgggc gaaatatcgc ttttattcag gcctattggc
     6121 aggcgaattt ctccttgtcg tgatgattgt gggtttcatc agcggccgtc cgatttcagt
     6181 tctcactttt ttgcagtgca ttgagttgct gctggcggga gcttttatca ggttaactgc
     6241 ggatgaaaaa aggcccttct tcagctggca gacggagcag cagctatgga gcggtttctc
     6301 aaaatatcgg tcttatctgt tttgtcttcc cctattctta gccacattag ccggcaccgc
     6361 tgtatccttg gcggtcattc cgatagccgg tctggtcata gtctattacc tgcaaaaaca
     6421 ggatggtggt ttctttgata caagcaaaag agaacggctt ggaagttaac ctgctgaaga
     6481 ctcatcaatt ttcaactata tcaatcgccg cgagctttct gaaaccgatc gaaagcgcgg
     6541 cggaacctga ggaagaaacg atttattttt acggcgccgc cgcatacctg aaggagcaaa
     6601 tcattgacga tttcggttgt gctgccggca gccgtttcat gtactcagcg aatctctttt
     6661 ttgatcagca gctgaaaacc tgcgggaccc gtttgattca cccattatat aatgggaatc
     6721 ttcatgttga cgccctgatg aaaacttttg cagacttgtc tttcccttct tctctttcat
     6781 tcgaagcagt tgaaaaggcc aggaatgagc tgctgctgaa aatcgaaaag aaattcactg
     6841 atcccttctc ctactcggcg gcgcgcttgg ctgaggaggt cttcggaaac ccgatgtacg
     6901 gcacaggcat gtttggccgg aaagacagga taaaggcgat tcatcctaaa cggtttcacg
     6961 acgcaacgga ctttatcgtt gatttagtgt cccagcaaaa acagctgaac atattgggac
     7021 aagtacaagc atgtgatgtt cggggacatg ccccgcaaac gtccgctgta acgtccgaaa
     7081 gaatacccgt aaaccggcat gtttttgaaa cagagacacg cagcgctgca ggtccttccg
     7141 tcttgacact cggatttgac tgcggagaga tgaaagatgc cagcgattat atcaaaatac
     7201 agctaataga cggattactg ggaaagtacg gccattccgc tttattcaag cacttcagag
     7261 agaaagatct ggcagtctat cacgttatca cccgttacga tgtcatgaac aatttgctgc
     7321 ttgtttcaat atgtacagat cagcttcatg agatagacat tcccccgcgc gttttggaag
     7381 ctgtctcagc ttttcataca gatgagcggg aactagaaca ggcaaagcag tttttacgca
     7441 atgaattgct gctgcaattc gattctcccg aaggtctatt ggcctatatg gggatcctgc
     7501 gccgcttctc ctgcacgaaa gaagccttgc tggatggcat ctcagcggtt acatgccgtg
     7561 atgtattgca attcatagcg accatcaatt atatcggagc tcatgtagta aggggatgaa
     7621 aagatggaaa agaaagcctt ttttcaacag ctggatgaac gaaccgatat cagatacaca
     7681 gacagcggac taaaaatatt cagattgaaa ttcccccgcg cccacctgcg gctgtgcaat
     7741 gtaaaaatcg attttggaag ccgggatgta tgtatacggg cagaatccgg tgatacactg
     7801 cttccgtatg gcacagcgca ttttttagag catcttctct tctggcataa cggccgcaat
     7861 ctgtacagtg atttttttgc gcatggcgcg cttttaaacg cattcactac ctacaccgat
     7921 accaatttca tgtttacctc attaccggat cggctcagac aaacgatccc catcctgctt
     7981 gatgctttat ggaaccactc atttgacaag aagattgtcg ctcaggaaaa agctgtgatt
     8041 acaagcgaaa ttcaaacagc acaccttaac catcagctct catatcatta tcagctgatc
     8101 agcatgcttt ctccctcctc accagctgcc gttttccccg caggcagaat cgaagatatt
     8161 gaggcgcttg acatcagtga tttacaaaaa gcctataagg ctgcctacca aacccatcgg
     8221 atgacgctgt ttttgattgg gggctcagaa aatacagaaa cgctattgcc tcctcacctc
     8281 cagctggaaa agcgtccgga ttatcatgct gaaagaaaaa tcatcccggc atgccctcca
     8341 gccctctcac aaaaaatgat gctgggtgat gaggagcgga tggaagatac atggaccgga
     8401 ttacagatcg gcgcacttcc cgggcaaaac gatctgttga cgatcaaact ttattgggat
     8461 atcgcggctc gtattctatt tcaattagat tcaccgtttt ttcaagagat tcagcaaacg
     8521 taccgcctgg aaatcgatcg tttgtcagcc gagacttata tctatgagga tggcggtttc
     8581 ttgatccttc acagtcaagg gacccattct tcagcttata tcgatgtggc ttcatactat
     8641 gtcacacaga agaaagaaca ggctgccgcc tggcttcaat acggcaagga ctctttgaca
     8701 gacgcgatca tttatgacag cgattatgtg cgtaaatgct tcgagtgggc agccgagtgt
     8761 gacaggtgcg attgctcgtt tcttgacatg taccacatca ttcaagatat ggatgcgcag
     8821 gttttcttgt ctctcattga tgcaatggca tcttctaaca aagcgatcat tcacgtttct
     8881 cagaaagagg cgatcagaca atgaaaaaaa acactgtctt taccctttta ttgctgctta
     8941 taggtatggc ggcttattcc ttcggctggg ttcaggccgt tgccgaagcc gccgcccact
     9001 atatacagat gatcaacaat gatgctgtac ggctcggact gctggcttgt accgctgccc
     9061 tcctgatgct gcctgctttt ctctatcttc actatgtcac ccaatctgtg aaaaacatga
     9121 cagcagcttt tcagaaactc acacagtctc atcaaagctg ctgtgacttt cagcaacaca
     9181 acttgtgcag ccgatatgca gaagacgtca aatcgctgcg tgacggctat aaaaacgtcc
     9241 gccaaacata cgtgatggct gccgtgttgt gccaagtcat catattcggc tgcatgttcg
     9301 aaatcgttaa agccgtccct ttccgccttc acacgccccc tgccctttca atgggacttg
     9361 cgatgctact gatcctgtat ttattgtttt gcatgcgaac gtatttgcgg cagcttttcc
     9421 ggcacggcag cctgttcaga aaagtgtttg cgggagtgct ggcagcagcc gggatttggt
     9481 ggatgctcag tttcactata agtgaactgc tgtttctgat tatcctggct gccatccagc
     9541 aaatcagatc atttatttat aagcgattct cttatcgcag caccgcttct cttgatctat
     9601 aaaatagcta catcacaatc gcagacgggc ccgcgccaac cggaatcacc ttcacggctg
     9661 tataatcact tgtgcggtac acagtcacag cattgtcgtt gggctgtgcc gcataaatat
     9721 actgtttgtc cggcgttacg gcggggtcaa aagcgccggg gagaggcacg tttgcaatga
     9781 tcctctgtct ggccgtatta actacgtata agttattaat gagaaacggt tcactatatg
     9841 gctctagaaa ataagctcta gtactatcga gagaaaatac aatcgtcctc agcgtttcaa
     9901 ataaacggtt aaagtcccct cccctgctta atggtgacaa actaatctcc gttacacctt
     9961 tcggccacag ctcaccattc aacacgtacg caaaatttcc agcgtaagga gttgcaatta
    10021 aactgggaaa ttcaaatgaa tctatgatac tttctaccaa ctgcccagta tttacatcat
    10081 atttatcaac cgaccaactg cttccattag cggtatagac atactgtcca ttcggatcaa
    10141 gagcaaagtc taaagcgccg ggtatcgcga ttacatcaat tactgattga ttggccgtgt
    10201 caatcatata tatagatccg gcggccatca cgtaggcgta ctcatctgtt ggatcaaatt
    10261 cgatctttct cggtcctcct ccaacagtaa tggtatttat gatggttaat gttttattat
    10321 caatcactga gacaaggttg gtattcccat ggaggacata cgtgaatgct ttatcgaaag
    10381 taacgcctag attagttggc acagcagaaa acaggattgt ttttacaaca gtgtttaaat
    10441 ctgcatcaat gaccgaaacc gtgctgtctc cagtattggc agtaaacaca tacgattgag
    10501 ggtctggcga tggcggcaaa acaagtgtcc cggccaccgt gagcggactg ccgtagaaag
    10561 gcggcacgat gagaagatct tccactgtca tctgactaaa atcaggacag cggtcagact
    10621 gtgctgcata ataaacaact tgatcaatct cttcagtatg aatcacagaa accgccccgt
    10681 ctccttgtcc atattgattt cgcacaggcg acacactgac aagaagcata atggtccctt
    10741 gtactctcac agcatatcga acaccaatat cttctgtttc cggcccagtc tggattaagc
    10801 aaggctcact gacacaggac aaattgtctg tactccatgt aacagccgct gacgcttcgg
    10861 ctgaatcaac cttgaagccc ttagggatat ctattggcac ttgaaacggc gcttcccggc
    10921 taatttcctc atcacaaaaa cagaaacaat tttcctgtaa agcagaaaga tcattctttt
    10981 tcatgaattc acgtcctttt aaaaatgcac aacatgcagc ggttaaatcg taatggcacc
    11041 cggtgaaacc ccaagagata tcacagtttc ctcagaataa tcatctgtgt tgtaaacaat
    11101 gatgctctgc tctataaaac gagttgcata cagaaaatcg ccattcgggg taaacgcata
    11161 gtctgttgct gattgcggaa gatttccaat tacacctgct ccattcggac tgacagaata
    11221 taaattgccg gtaaagtcgt catataaata cacacctgtt ccgctcgtaa acattctata
    11281 ttggccgtca ggctccagtt cttgggtatt gctgatcgta aacgtattta agtcaataac
    11341 cgtcaaataa ttgaataaga attcttgttc taagacatac gcataccgct ccggagaatc
    11401 tgtttctatg gatgatacga taagctctcg ttcaatcgtt cctgtgactt caccggtgga
    11461 taagtccact ttttgcacta acccaaaatt aagaacatag gcgaacaacc cattggggtc
    11521 aattgcaata tcaaaacctt ctatatagac ctctcaacag tcaacgtatc aattccaatc
    11581 acataaatgg cagtaccggt gaaaacataa gcaaactcat gattagggat aaatctaatc
    11641 aatcgaggcg gctgatccag caatatagtt gctgtcactg ttaatgtgtc ataatcgatg
    11701 acagaaatca cattattgtt gggatgtaag acaaacacag cgcttttatc tggcgtaatt
    11761 tcaatacctg ccggattgta cggaagagca atcgttgtca caacagtatg ggtgtttgta
    11821 tcaatcacag aaactgattg atcatttgga ttcgctgtaa acgcgtagac gggttccggc
    11881 tccggtacaa gcacaatcgt ccccgtcacc gataaaggac tgccgtaaaa cggcggaaca
    11941 acaacaaggt tctcaatcgt gatgttactg atatccgggc aatcatccgg ttcatcggaa
    12001 taatagacga cttgatcgat ttctgcattg tgaatgacgg aaacagcccc atccccttgt
    12061 ccatattgat ttcgcacagg tgagacactg acgagcagcg taacggttcc ctgcagacgc
    12121 actgcaaatt gaacaccgac ctcatcaggc tctggccccg tttgaattaa gcaacggtca
    12181 ctgacacaag aaaggctgtc tgcattccac gtcacgtttg caacagcttc agccggatca
    12241 acgacaaatc cttcaggtaa ttcaatcggc gcttgaaaca tggcttctcg gcttgcttct
    12301 ccctcacaaa aacataagca ctcttcttgt tctgctcctg ctttttcttt aaaggaaagc
    12361 ttgttttttc tcattccttc acttcctttt cagacataca ctgctcacgc agatataaca
    12421 gaatatggaa gagtaacgtg tttgcttgta caaattactg agggtaaaag cttctttttg
    12481 aaaatatatc tccaaacatg cggtgtaacg aaagaaaaaa ttgcggtttt tttgcgcttc
    12541 tcacaagaat gttgatgata aaatatgaca tatatagaat tatgaaggga gggatttgca
    12601 aacgtgacag gtgtcatatc ttcttcttcc atcggagaaa agattaacga atggtatatg
    12661 tacatacgcc gattcagcat acccgatgca gaatatttgc gacgagaaat caagcaagag
    12721 ctggatcaaa tggaagaaga tcaagacctt catttgtact attcactgat ggagtttcgg
    12781 cacaacctga tgcttgagta ccttgaaccg ttagaaaaaa tgaggattga ggaacagccg
    12841 agactgtctg atctgctgct tgagattgat aaaaaacagg ctcgtttaac aggtctgctt
    12901 gagtactatt ttaatttctt cagaggcatg tatgagctgg atcagcggga atatctgtcg
    12961 gctattaaat ttttcaaaaa ggccgaaagc aagctgatat tcgttaagga tcggatagag
    13021 aaagctgagt ttttctttaa gatgtctgaa tcttattact atatgaaaca aacgtatttt
    13081 tcaatggact atgcacggca agcatatgaa atatacaaag aaaatgaagc ttataatata
    13141 agattgctgc agtgtcattc tttatttgcc accaattttt tagatttaaa acagtatgag
    13201 gatgccgtct cacattttca aaaagcttat tctatggcag aagctgaaaa gcagccccaa
    13261 ttaatgggaa gaactttgta caatatcggg ctttgtaaaa acagccaaag ccaatatgag
    13321 gatgccataa catatttcaa aagagcaata gctgtttttg aagaatcaaa tattcttcct
    13381 tccttacctc aagcgtattt tttaattaca cagatccatt ataaattagg aaaaatggat
    13441 aaagctcatg aatatcatag taagggaatg gcttattcac aaaaggccgg agatgtaata
    13501 tatttatcag agtttgaatt tttgaaatct ttatacttat caggcccgga tgaagaagca
    13561 attcaaggat tttttgattt tctcgaaagt aaaatgttgt atgctgatct tgaagatttc
    13621 actattgatg tggcaaaata ttatcatgaa cgtaaaaatt ttcaaaaagc ttctgcttat
    13681 tttttgaagg tggaacaagt aaggcaactt attcaaggag gagtgagttt gtatgaaatt
    13741 gaagtctaaa ctattactct cttgtctggc tctaagcact gtgttcgtgg caacaactat
    13801 tgcaaatgca cctacacacc aaattgaagt tgcacaacga ggaatgattt aaccgccgtc
    13861 catcggcggt ttttttgtcc cctctttacc cagtctccca atccattcta tgattttttc
    13921 aataatctta aaaatagtgg aaatgcagca tgtctctaaa aagtgtgaga acccacttta
    13981 ctcaatggaa tcgagaaaat gatgtgacgg agttcgaaac gtcgagtgcg acagttgaac
    14041 aggcagctga gacaatcggc gtaagcctgt ctagaatcgc caagtccctg tccttcagag
    14101 gggaaggaga tcaggtgatt ctgattgtgg cagccggcga tgccaagatc gacaacaaaa
    14161 agtccaggca aacatttggc tttaaagcaa gaatgctctc tcctaatgag gtactggagc
    14221 agacaggcca tgaaattgga ggagtttgcc caattggata gactcatgat cctgag
//
