LOCUS       gnlProkkaKFEIOIPB_19    1989 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KFEIOIPB_19.
ACCESSION   gnlProkkaKFEIOIPB_19
VERSION     gnlProkkaKFEIOIPB_19
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 20:01:52
            Original ID  :: gnl|Prokka|KFEIOIPB_19
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 1989
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..1989
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[0:1989]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..1989
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..1989
                     /SMILES="NC(CC(C)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..1989
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             complement(1..1989)
                     /NRPS_PKS="Domain: AMP-binding (46-434). E-value: 9.7e-107.
                     Score: 348.9. Matches aSDomain:
                     nrpspksdomains_ctg19_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (539-607). E-value: 3.5e-28. Score:
                     89.5. Matches aSDomain: nrpspksdomains_ctg19_1_PCP.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     351.7; E-value: 9e-107)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg19_1"
                     /sec_met_domain="AMP-binding (E-value: 3.4e-116, bitscore:
                     374.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 6.1e-20, bitscore:
                     57.9, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 9.9e-12, bitscore:
                     30.6, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDAVSGNPNQPLSSLSLVTETEKQALLEAWKGKALPVPTDKTVHQ
                     LFEETVQRHKDRPAVTYNGQSWTYGELNAKANRLARILMDCGISPDDRVGILTKPSLEM
                     SAAVLGVLKAGAAFVPIDPDYPDQRIEYILQDSGAKLLLKQEGISVPDSFSGDVILLDG
                     SRTILSLPLDENDEENPETAVTAENLAYMIYTSGTTGQPKGVMVEHHALVNLCFWHHDA
                     FSMTAEDRSAKYAGFGFDASIWEMFPTWTIGAELHVIDEAIRLDIVRLNDYFETNGVTI
                     TFLPTQLAEQFMELENTSLRVLLTGGDKLKRAVKKPYTLVNNYGPTENTVVATSAEIHP
                     EEGSLSIGRAIANTRVYILGEGNQVQPEGVAGELCVAGRGLARGYLNREDETAKRFVAD
                     PFVPGERMYRTGDLVKWTGGGIEYIGRIDQQVKVRGYRIELSEIEVQLAQLSEVQDAAV
                     TAVKDKGGNTAIAAYVTPETADIEALKSALKETLPDYMIPAFWVTLNELPVTANGKVDR
                     KALPEPDIEAGSGEYKAPTTDMEELLAGIWQDVLGMSEVGVTDNFFSLGGDSIKGIQMA
                     SRLNQHGWKLEMKDLFQHPTIEELTQYVERAEGKQADQGPVEGEVILTPIQRWFFEKNF
                     TNKHHWNQSVMLHAKKGFGPERVEYTLQ"
     CDS_motif       complement(94..123)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg19_1_0007"
                     /evalue="4.20E-05"
                     /label="NRPS-E1"
                     /locus_tag="ctg19_1"
                     /protein_end="632"
                     /protein_start="622"
                     /score="16.2"
                     /tool="antismash"
                     /translation="LTPIQRWFFE"
     aSDomain        complement(169..372)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg19_1_PCP.1"
                     /evalue="3.50E-28"
                     /label="ctg19_1_PCP.1"
                     /locus_tag="ctg19_1"
                     /protein_end="607"
                     /protein_start="539"
                     /score="89.5"
                     /tool="antismash"
                     /translation="EELLAGIWQDVLGMSEVGVTDNFFSLGGDSIKGIQMASRLNQHGW
                     KLEMKDLFQHPTIEELTQYVERA"
     aSModule        complement(169..1851)
                     /complete
                     /domains="nrpspksdomains_ctg19_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg19_1_PCP.1"
                     /locus_tags="ctg19_1"
                     /monomer_pairings="Leu -> Leu"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(280..309)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg19_1_0006"
                     /evalue="7.40E-03"
                     /label="PCP_mC"
                     /locus_tag="ctg19_1"
                     /protein_end="570"
                     /protein_start="560"
                     /score="9.8"
                     /tool="antismash"
                     /translation="NFFSLGGDSI"
     CDS_motif       complement(658..723)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg19_1_0005"
                     /evalue="1.30E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg19_1"
                     /protein_end="444"
                     /protein_start="422"
                     /score="36.4"
                     /tool="antismash"
                     /translation="YIGRIDQQVKVRGYRIELSEIE"
     aSDomain        complement(688..1851)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg19_1_AMP-binding.1"
                     /evalue="9.70E-107"
                     /label="ctg19_1_AMP-binding.1"
                     /locus_tag="ctg19_1"
                     /protein_end="434"
                     /protein_start="46"
                     /score="348.9"
                     /specificity="substrate consensus: Leu"
                     /tool="antismash"
                     /translation="FEETVQRHKDRPAVTYNGQSWTYGELNAKANRLARILMDCGISPD
                     DRVGILTKPSLEMSAAVLGVLKAGAAFVPIDPDYPDQRIEYILQDSGAKLLLKQEGISV
                     PDSFSGDVILLDGSRTILSLPLDENDEENPETAVTAENLAYMIYTSGTTGQPKGVMVEH
                     HALVNLCFWHHDAFSMTAEDRSAKYAGFGFDASIWEMFPTWTIGAELHVIDEAIRLDIV
                     RLNDYFETNGVTITFLPTQLAEQFMELENTSLRVLLTGGDKLKRAVKKPYTLVNNYGPT
                     ENTVVATSAEIHPEEGSLSIGRAIANTRVYILGEGNQVQPEGVAGELCVAGRGLARGYL
                     NREDETAKRFVADPFVPGERMYRTGDLVKWTGGGIEYIGRIDQQVKVR"
     CDS_motif       complement(802..891)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg19_1_0004"
                     /evalue="2.50E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg19_1"
                     /protein_end="396"
                     /protein_start="366"
                     /score="51.7"
                     /tool="antismash"
                     /translation="PEGVAGELCVAGRGLARGYLNREDETAKRF"
     CDS_motif       complement(994..1023)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg19_1_0003"
                     /evalue="3.50E-03"
                     /label="NRPS-A_a5"
                     /locus_tag="ctg19_1"
                     /protein_end="332"
                     /protein_start="322"
                     /score="10.0"
                     /tool="antismash"
                     /translation="NYGPTENTVV"
     CDS_motif       complement(1363..1422)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg19_1_0002"
                     /evalue="4.50E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg19_1"
                     /protein_end="209"
                     /protein_start="189"
                     /score="34.4"
                     /tool="antismash"
                     /translation="AYMIYTSGTTGQPKGVMVEH"
     CDS_motif       complement(1624..1665)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg19_1_0001"
                     /evalue="5.90E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg19_1"
                     /protein_end="122"
                     /protein_start="108"
                     /score="19.3"
                     /tool="antismash"
                     /translation="LGVLKAGAAFVPID"
ORIGIN
        1 ctgcaatgtg tactccaccc gttcaggacc aaagcccttt ttggcgtgaa gcatcacaga
       61 ttggttccag tggtgcttgt tcgtgaagtt cttttcaaag aaccagcgct ggatcggcgt
      121 caggatgact tcgccctcca ccgggccttg gtctgcctgt ttgccttcgg cacgctctac
      181 atattgggta agctcttcga tcgtcgggtg ctggaagaga tctttcattt ccagcttcca
      241 gccgtgctgg ttcaagcggc tcgccatttg aattcctttg atggaatctc cgccaagcga
      301 gaagaaattg tcggtgacac cgacttcaga cattccaagc acgtcctgcc agatgccggc
      361 aagcagctct tccatgtcgg tcgtcggcgc tttgtattct ccgcttcccg cttcgatgtc
      421 cggctcaggc aaggctttgc ggtccacttt gccgtttgcc gtaaccggaa gctcgttcag
      481 cgtcacccag aacgccggga tcatgtaatc cggcagggtt tccttcagtg ctgatttcag
      541 tgcttctatg tcagctgttt ccggtgtgac atacgccgcg atcgctgtgt tgcctccttt
      601 atctttgaca gctgtcaccg ccgcatcctg cacctcagaa agctgggcga gctggacttc
      661 aatttctgaa agctcgatcc ggtagccgcg gaccttgacc tgctggtcga tccggccgat
      721 gtattcgatg ccgccgcccg tccatttcac caaatcgccg gtgcggtaca tgcgctcacc
      781 cggcacaaac ggatcagcga caaaccgctt cgcggtttcg tcttctcgat tcagatagcc
      841 tcgcgctaat ccgcgtcccg ccacgcaaag ctctccggct acgccttccg gctgcacctg
      901 attgccctcg ccgagaatgt acactctcgt attggcaatg gcccgtccga tggaaagcga
      961 gccttcctcc ggatggattt ctgcgcttgt ggcaacgacc gtgttttctg tcggcccgta
     1021 gttgttgacg agtgtgtacg gctttttcac ggcgcgcttc agcttgtctc cgcctgtcaa
     1081 gagaacacgg agtgatgtgt tctcaagctc catgaactgt tccgcaagct gtgtcggcag
     1141 gaacgtgatc gttacgccgt tcgtttcaaa ataatcgttc aggcggacga tatcgaggcg
     1201 gatcgcttca tcaatgacgt gaagttcggc gccgatcgtc caggtcggga acatctccca
     1261 aatggaagcg tcgaacccga agcccgcgta cttcgcactg cggtcctccg ctgtcatgct
     1321 gaacgcgtcg tggtgccaga agcacaggtt cacaagcgca tggtgctcga ccatgacacc
     1381 cttcggctgt ccggtcgttc ctgacgtgta aatcatgtac gccaagttct ccgcggttac
     1441 agccgtctct ggattttcct catcgttttc atcaagcggc aagcttagaa tcgtgcggct
     1501 tccgtcgaga agaataacgt ctcctgagaa gctatccggc actgaaatgc cttcttgctt
     1561 caagagaagc ttcgcgccgc tgtcctgtaa aatatactca atccgctgat ccgggtagtc
     1621 aggatcaatc ggcacaaacg ccgctcccgc ttttaagacg ccaagcaccg cggcggacat
     1681 ttcaagcgac ggcttcgtga gaatgccgac gcggtcatcc gggctgatgc cgcagtccat
     1741 cagaatccgc gcgagacggt ttgccttcgc attcagctcg ccgtacgtcc aagactggcc
     1801 gttgtaggtg acagccgggc ggtctttgtg gcgctggaca gtctcttcga atagctgatg
     1861 aactgttttg tctgtcggca caggcagcgc tttgcccttc catgcctcaa gaagcgcttg
     1921 tttttctgtc tcggtgacca gtgacaggct ggaaagcggc tggttcgggt tcccgctaac
     1981 agcatcaaa
//
