LOCUS       gnlProkkaLHNGMDCD_22    7986 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LHNGMDCD_22.
ACCESSION   gnlProkkaLHNGMDCD_22
VERSION     gnlProkkaLHNGMDCD_22
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 18:54:15
            Original ID  :: gnl|Prokka|LHNGMDCD_22
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 7986
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..7986
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[2476:6304]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2477..6304
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..7986
                     /SMILES="NC(CC(C)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..7986
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             complement(392..1618)
                     /gene_functions="transport (smcogs) SMCOG1137:Major
                     facilitator superfamily MFS 1 (Score: 338.4; E-value:
                     8.1e-103)"
                     /gene_kind="transport"
                     /locus_tag="ctg22_1"
                     /transl_table=11
                     /translation="MRTSPRMKWFVLLFTFVFAIGMNSFRNSFQFFMLPMADAFHADRS
                     LISVSVSIFMITTGIVQFFVGFFIDRFSVRKIMALGAVCISASFLVLPYSPNVHVFSAI
                     YGVLGGIGYSCAVGVTTQYFISRWFDTHKGLALAILTNANSAGLLLLSPIWAEAPYHAG
                     WQSTYTILGIVMAAVLLPLFVIGMKHPPYAQAESVKKSYDWRGFWNVMKQSRLIHILYF
                     GVCTCGFTMGIIDAHLVPMLKDAHVSHVNGMMAAFGAFIIIGGLLAGWLSDLLGSRSVM
                     LSILFFIRLLSLICLLIPILGIHHSDLWYFGFILLFGLSYTGVIPLTAASISESYQTGL
                     IGSLLGINFFIHQVAGALSVYAGGLFFDMTHGYLLIVAVCIVFVGLSAVIELVPFLDKQ
                     KAKETHQSI"
     CDS             complement(1720..2448)
                     /NRPS_PKS="Domain: Thioesterase (14-231). E-value: 3.7e-55.
                     Score: 179.7. Matches aSDomain:
                     nrpspksdomains_ctg22_2_Thioesterase.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004:thioesterase (Score: 213; E-value: 5.8e-65)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_2"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1e-16, bitscore:
                     50.3, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 4.4e-08, bitscore: 21.1,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQLFKSFDASEKTQLICFPFAGGYSASFRPLHAFLQGECEMLAA
                     EPPGHGTNQTSAIEDLEELTDLYKQELNLRPDRPFVLFGHSMGGMITFRLAQKLEREGI
                     FPQAVIISAIQPPHIQRKKVSHLPDDQFLDHIIQLGGMPAELVENKEVMSFFLPSFRSD
                     YRALEQFELYDLAQIQSPVHVFNGLDDKKCIRDAEGWKKWAKDITFHQFDGGHMFLLSQ
                     TEEVAERIFAILNQHPIIQP"
     aSDomain        complement(1756..2406)
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg22_2_Thioesterase.1"
                     /evalue="3.70E-55"
                     /label="ctg22_2_Thioesterase.1"
                     /locus_tag="ctg22_2"
                     /protein_end="231"
                     /protein_start="14"
                     /score="179.7"
                     /tool="antismash"
                     /translation="QLICFPFAGGYSASFRPLHAFLQGECEMLAAEPPGHGTNQTSAIE
                     DLEELTDLYKQELNLRPDRPFVLFGHSMGGMITFRLAQKLEREGIFPQAVIISAIQPPH
                     IQRKKVSHLPDDQFLDHIIQLGGMPAELVENKEVMSFFLPSFRSDYRALEQFELYDLAQ
                     IQSPVHVFNGLDDKKCIRDAEGWKKWAKDITFHQFDGGHMFLLSQTEEVAERIF"
     CDS_motif       complement(2152..2223)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg22_2_0001"
                     /evalue="1.90E-08"
                     /label="NRPS-te1"
                     /locus_tag="ctg22_2"
                     /protein_end="99"
                     /protein_start="75"
                     /score="26.7"
                     /tool="antismash"
                     /translation="PDRPFVLFGHSMGGMITFRLAQKL"
     CDS             complement(2477..6304)
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (0-32). E-value: 1.4e-16.
                     Score: 51.3. Matches aSDomain:
                     nrpspksdomains_ctg22_3_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (9-308). E-value:
                     1.5e-118. Score: 387.2. Matches aSDomain:
                     nrpspksdomains_ctg22_3_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (469-867). E-value:
                     3.3e-111. Score: 363.6. Matches aSDomain:
                     nrpspksdomains_ctg22_3_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (973-1042). E-value: 1.5e-25. Score:
                     81.1. Matches aSDomain: nrpspksdomains_ctg22_3_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (1060-1267). E-value:
                     1.6e-37. Score: 122.0. Matches aSDomain:
                     nrpspksdomains_ctg22_3_Thioesterase.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     331.7; E-value: 1.4e-100)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_3"
                     /sec_met_domain="Condensation (E-value: 1.3e-94, bitscore:
                     304.7, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 4.8e-123, bitscore:
                     398.8, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.4e-19, bitscore:
                     58.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQFSKDQVQDMYYLSPMQEGMLFHAILNPGQSFYLEQITMKVKG
                     SLNIKCLEESMNVIMDRYDVFRTVFIYEKVKRPVQVVLKKRQFHIEEIDLTHLTGSEQT
                     AKINEYKEQDKIRGFDLTRDIPMRAAIFKKAEESFEWVWSYHHIILDGWCFGIVVQDLF
                     KVYNALREQKPYSLPPVKPYKDYIKWLEKQDKQASLRYWREYLEDFEGQTTFAEQRKKQ
                     KDGYEPKELLFSLPEAETKAFTELAKSQHTTLSTALQAVWSVLISRYQQSGDLTFGTVV
                     SGRPAEIKGVEHMVGLFINVVPRRVKLSEGITFNGLLKQLQEQSLQSEPHQYVPLYDIQ
                     SQADQPKLIDHIIVFENYPLQDAKNEESSENGFDMVDVHVFEKSNYDLNLMASPGDEML
                     IKFAYNENVFDEAFILRLKSQLLTAIQQLIQNPDQPVSTINLVDDREREFLLTGLNPPA
                     QAHDTKPLTDWFKEAVNVNPDAPALTYSGQTLSYRELDEEANRLARRLQKHGAGKGSVV
                     ALYTKRSLELVIGILGVLKAGAAYLPVDPKLPEDRISYMLADSAAACLLTHQKMKEQAA
                     ELPYTGTTLFIDDQTRFEEQASDPATAIDPNDPAYIMYTSGTTGKPKGNITTHANIQGL
                     VKHVDYMAFSEKDTFLSVSNYAFDAFTFDFYASMLNAARLIIADEHTLLDTERLTDLIL
                     QENVNVMFATTALFNLLTDAGEDWMKGLRCILFGGERASVPHVRKALRVMGPGKLINCY
                     GPTEGTVFATAHVVHDIPDSISSLPIGKPISNASVYILNEQSQLQPFGAIGELCISGMG
                     VSKGYVNRADLTKEKFIKNPFKPGETLYRTGDLARWLPDGTIEYAGRIDDQVKIRGHRI
                     ELEEIEKQLQEYPGVKDAVVVADRPESGDASINAYLVNRTQLSAEDVKAHLKKQLPAYM
                     VPQTFTFLDEIPLTTNGKVNKRLLPKPDQDQLAEEWIGPRNEMEETIAQIWSEVLGRKQ
                     IGIHDDFFALGGHSLKAMTAASRIKKELGIDLPVKLLFEAPTIAGISAYVKNGGPDGLQ
                     DVTIMNQDQEQIIFAFPPILGYGLMYQNLSSRLPSYKLCAFDFIEEEDRLDRYADLIQK
                     LQPEGPLTLFGYSAGCSLAFEAAKKLEGQGRIVQRIIMVDSYKKQGVSDLDGRTVESDV
                     EALMNVNRDNEALNSEAVKQGLKQKTHAFYSYYVNLISTGQVKADIDLLTSGADFDMPE
                     WLASWEEATTGAYRMKRGFGTHAEMLQGETLDRNAEILLEFLNTQTVTVS"
     aSDomain        complement(2504..3124)
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg22_3_Thioesterase.1"
                     /evalue="1.60E-37"
                     /label="ctg22_3_Thioesterase.1"
                     /locus_tag="ctg22_3"
                     /protein_end="1267"
                     /protein_start="1060"
                     /score="122.0"
                     /tool="antismash"
                     /translation="IFAFPPILGYGLMYQNLSSRLPSYKLCAFDFIEEEDRLDRYADLI
                     QKLQPEGPLTLFGYSAGCSLAFEAAKKLEGQGRIVQRIIMVDSYKKQGVSDLDGRTVES
                     DVEALMNVNRDNEALNSEAVKQGLKQKTHAFYSYYVNLISTGQVKADIDLLTSGADFDM
                     PEWLASWEEATTGAYRMKRGFGTHAEMLQGETLDRNAEILLEFL"
     aSModule        complement(2504..6277)
                     /complete
                     /domains="nrpspksdomains_ctg22_3_Condensation_DCL.1"
                     /domains="nrpspksdomains_ctg22_3_AMP-binding.1"
                     /domains="nrpspksdomains_ctg22_3_PCP.1"
                     /domains="nrpspksdomains_ctg22_3_Thioesterase.1"
                     /final_module
                     /locus_tags="ctg22_3"
                     /monomer_pairings="Leu -> Leu"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(2906..2980)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg22_3_0011"
                     /evalue="6.30E-10"
                     /label="NRPS-te1"
                     /locus_tag="ctg22_3"
                     /protein_end="1133"
                     /protein_start="1108"
                     /score="31.5"
                     /tool="antismash"
                     /translation="QPEGPLTLFGYSAGCSLAFEAAKKL"
     aSDomain        complement(3179..3385)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg22_3_PCP.1"
                     /evalue="1.50E-25"
                     /label="ctg22_3_PCP.1"
                     /locus_tag="ctg22_3"
                     /protein_end="1042"
                     /protein_start="973"
                     /score="81.1"
                     /tool="antismash"
                     /translation="EETIAQIWSEVLGRKQIGIHDDFFALGGHSLKAMTAASRIKKELG
                     IDLPVKLLFEAPTIAGISAYVKNG"
     CDS_motif       complement(3674..3739)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg22_3_0010"
                     /evalue="9.60E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg22_3"
                     /protein_end="877"
                     /protein_start="855"
                     /score="36.8"
                     /tool="antismash"
                     /translation="YAGRIDDQVKIRGHRIELEEIE"
     aSDomain        complement(3704..4897)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg22_3_AMP-binding.1"
                     /evalue="3.30E-111"
                     /label="ctg22_3_AMP-binding.1"
                     /locus_tag="ctg22_3"
                     /protein_end="867"
                     /protein_start="469"
                     /score="363.6"
                     /specificity="substrate consensus: Leu"
                     /tool="antismash"
                     /translation="FKEAVNVNPDAPALTYSGQTLSYRELDEEANRLARRLQKHGAGKG
                     SVVALYTKRSLELVIGILGVLKAGAAYLPVDPKLPEDRISYMLADSAAACLLTHQKMKE
                     QAAELPYTGTTLFIDDQTRFEEQASDPATAIDPNDPAYIMYTSGTTGKPKGNITTHANI
                     QGLVKHVDYMAFSEKDTFLSVSNYAFDAFTFDFYASMLNAARLIIADEHTLLDTERLTD
                     LILQENVNVMFATTALFNLLTDAGEDWMKGLRCILFGGERASVPHVRKALRVMGPGKLI
                     NCYGPTEGTVFATAHVVHDIPDSISSLPIGKPISNASVYILNEQSQLQPFGAIGELCIS
                     GMGVSKGYVNRADLTKEKFIKNPFKPGETLYRTGDLARWLPDGTIEYAGRIDDQVKIR"
     CDS_motif       complement(3821..3910)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg22_3_0009"
                     /evalue="5.50E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg22_3"
                     /protein_end="828"
                     /protein_start="798"
                     /score="41.1"
                     /tool="antismash"
                     /translation="PFGAIGELCISGMGVSKGYVNRADLTKEKF"
     CDS_motif       complement(4418..4477)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg22_3_0008"
                     /evalue="9.20E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg22_3"
                     /protein_end="629"
                     /protein_start="609"
                     /score="24.4"
                     /tool="antismash"
                     /translation="AYIMYTSGTTGKPKGNITTH"
     CDS_motif       complement(4670..4711)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg22_3_0007"
                     /evalue="2.60E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg22_3"
                     /protein_end="545"
                     /protein_start="531"
                     /score="17.4"
                     /tool="antismash"
                     /translation="LGVLKAGAAYLPVD"
     CDS_motif       complement(5228..5341)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg22_3_0006"
                     /evalue="1.00E-17"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="ctg22_3"
                     /protein_end="359"
                     /protein_start="321"
                     /score="56.6"
                     /tool="antismash"
                     /translation="QEQSLQSEPHQYVPLYDIQSQADQPKLIDHIIVFENYP"
     aSDomain        complement(5381..6277)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg22_3_Condensation_DCL.1"
                     /domain_subtypes="Condensation_DCL"
                     /evalue="1.50E-118"
                     /label="ctg22_3_Condensation_DCL.1"
                     /locus_tag="ctg22_3"
                     /protein_end="308"
                     /protein_start="9"
                     /score="387.2"
                     /tool="antismash"
                     /translation="QDMYYLSPMQEGMLFHAILNPGQSFYLEQITMKVKGSLNIKCLEE
                     SMNVIMDRYDVFRTVFIYEKVKRPVQVVLKKRQFHIEEIDLTHLTGSEQTAKINEYKEQ
                     DKIRGFDLTRDIPMRAAIFKKAEESFEWVWSYHHIILDGWCFGIVVQDLFKVYNALREQ
                     KPYSLPPVKPYKDYIKWLEKQDKQASLRYWREYLEDFEGQTTFAEQRKKQKDGYEPKEL
                     LFSLPEAETKAFTELAKSQHTTLSTALQAVWSVLISRYQQSGDLTFGTVVSGRPAEIKG
                     VEHMVGLFINVVPRRVKL"
     CDS_motif       complement(5390..5485)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg22_3_0005"
                     /evalue="1.30E-18"
                     /label="C5_DCL_263-294"
                     /locus_tag="ctg22_3"
                     /protein_end="305"
                     /protein_start="273"
                     /score="59.4"
                     /tool="antismash"
                     /translation="DLTFGTVVSGRPAEIKGVEHMVGLFINVVPRR"
     CDS_motif       complement(5723..5761)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg22_3_0004"
                     /evalue="5.50E-04"
                     /label="C4_DCL_171-183"
                     /locus_tag="ctg22_3"
                     /protein_end="194"
                     /protein_start="181"
                     /score="12.4"
                     /tool="antismash"
                     /translation="PYKDYIKWLEKQD"
     CDS_motif       complement(5807..5872)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg22_3_0003"
                     /evalue="1.70E-11"
                     /label="C3_DCL_135-156"
                     /locus_tag="ctg22_3"
                     /protein_end="166"
                     /protein_start="144"
                     /score="36.5"
                     /tool="antismash"
                     /translation="YHHIILDGWCFGIVVQDLFKVY"
     CDS_motif       complement(6089..6205)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg22_3_0002"
                     /evalue="4.00E-12"
                     /label="C2_DCL_024-062"
                     /locus_tag="ctg22_3"
                     /protein_end="72"
                     /protein_start="33"
                     /score="38.4"
                     /tool="antismash"
                     /translation="FYLEQITMKVKGSLNIKCLEESMNVIMDRYDVFRTVFIY"
     aSDomain        complement(6209..6304)
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg22_3_NRPS-COM_Nterm.1"
                     /evalue="1.40E-16"
                     /label="ctg22_3_NRPS-COM_Nterm.1"
                     /locus_tag="ctg22_3"
                     /protein_end="32"
                     /protein_start="0"
                     /score="51.3"
                     /tool="antismash"
                     /translation="MSQFSKDQVQDMYYLSPMQEGMLFHAILNPGQ"
     CDS_motif       complement(6227..6268)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg22_3_0001"
                     /evalue="3.00E-05"
                     /label="C1_DCL_004-017"
                     /locus_tag="ctg22_3"
                     /protein_end="26"
                     /protein_start="12"
                     /score="15.8"
                     /tool="antismash"
                     /translation="YYLSPMQEGMLFHA"
     CDS             complement(6341..7984)
                     /NRPS_PKS="Domain: PCP (3-71). E-value: 2.7e-28. Score:
                     89.9. Matches aSDomain: nrpspksdomains_ctg22_4_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (81-384). E-value:
                     6.4e-161. Score: 528.6. Matches aSDomain:
                     nrpspksdomains_ctg22_4_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (388-537). E-value: 7.4e-55.
                     Score: 176.9. Matches aSDomain:
                     nrpspksdomains_ctg22_4_TIGR01720.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     130.9; E-value: 1.3e-39)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_4"
                     /sec_met_domain="PP-binding (E-value: 1.9e-19, bitscore:
                     58.2, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 2.2e-86, bitscore:
                     277.7, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDMEELLAGIWQDVLGMSEVGVTDNFFSLGGDSIKGIQMASRLNQ
                     HGWKLEMKDLFQHPTIEELTQYVERAEGKQADQGPVEGEVILTPIQRWFFEKNFTNKHH
                     WNQSVMLHAKKGFGPERVEKTLQALIEHHDALRMVYREENGDIVQAYKPIGESKVSFEI
                     VDLYGSDEEMLRSQIKILANKLQSSLDLRTGPLLKAEQYRTEAGDHLLIAVHHLVVDGV
                     SWRILLEDFASGYMQAEKEESLVFPQKTNSFKDWAEELAAFSQSAHLLQQAEYWSQIAA
                     EQVSPLPKDCETEQRIVKDTSSVLCELTEEDTKHLLTDVHQPYGTEINDILLSALGLTM
                     KEWTKGAKIGINLEGHGREDIIPNVNISRTVGWFTAQYPVVLDISEADASAVIKTVKEN
                     LRRIPDKGVGYGILRYFTETAETKGFTPEISFNYLGQFDSEVKTDFFEPSAFDMGRQVS
                     EESEALYALSFSGMIRNGRFVLSCSYNEKEFERATIEERMERFKENLLMLIRHCTEKED
                     KEFTPSDFSAEDLEMDEMGDIFDMLEENLK"
     aSDomain        complement(6374..6820)
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg22_4_TIGR01720.1"
                     /evalue="7.40E-55"
                     /label="ctg22_4_TIGR01720.1"
                     /locus_tag="ctg22_4"
                     /protein_end="537"
                     /protein_start="388"
                     /score="176.9"
                     /tool="antismash"
                     /translation="ASAVIKTVKENLRRIPDKGVGYGILRYFTETAETKGFTPEISFNY
                     LGQFDSEVKTDFFEPSAFDMGRQVSEESEALYALSFSGMIRNGRFVLSCSYNEKEFERA
                     TIEERMERFKENLLMLIRHCTEKEDKEFTPSDFSAEDLEMDEMGD"
     aSModule        complement(6374..7975)
                     /domains="nrpspksdomains_ctg22_4_PCP.1"
                     /domains="nrpspksdomains_ctg22_4_Epimerization.1"
                     /domains="nrpspksdomains_ctg22_4_TIGR01720.1"
                     /incomplete
                     /locus_tags="ctg22_4"
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       complement(6677..6706)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg22_4_0006"
                     /evalue="1.50E-03"
                     /label="NRPS-E7"
                     /locus_tag="ctg22_4"
                     /protein_end="436"
                     /protein_start="426"
                     /score="11.0"
                     /tool="antismash"
                     /translation="PEISFNYLGQ"
     CDS_motif       complement(6740..6799)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg22_4_0005"
                     /evalue="8.20E-12"
                     /label="NRPS-E6"
                     /locus_tag="ctg22_4"
                     /protein_end="415"
                     /protein_start="395"
                     /score="37.1"
                     /tool="antismash"
                     /translation="VKENLRRIPDKGVGYGILRY"
     aSDomain        complement(6833..7741)
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg22_4_Epimerization.1"
                     /evalue="6.40E-161"
                     /label="ctg22_4_Epimerization.1"
                     /locus_tag="ctg22_4"
                     /protein_end="384"
                     /protein_start="81"
                     /score="528.6"
                     /tool="antismash"
                     /translation="EGEVILTPIQRWFFEKNFTNKHHWNQSVMLHAKKGFGPERVEKTL
                     QALIEHHDALRMVYREENGDIVQAYKPIGESKVSFEIVDLYGSDEEMLRSQIKILANKL
                     QSSLDLRTGPLLKAEQYRTEAGDHLLIAVHHLVVDGVSWRILLEDFASGYMQAEKEESL
                     VFPQKTNSFKDWAEELAAFSQSAHLLQQAEYWSQIAAEQVSPLPKDCETEQRIVKDTSS
                     VLCELTEEDTKHLLTDVHQPYGTEINDILLSALGLTMKEWTKGAKIGINLEGHGREDII
                     PNVNISRTVGWFTAQYPVVLDI"
     CDS_motif       complement(6839..6889)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg22_4_0004"
                     /evalue="1.40E-08"
                     /label="NRPS-E5"
                     /locus_tag="ctg22_4"
                     /protein_end="382"
                     /protein_start="365"
                     /score="26.8"
                     /tool="antismash"
                     /translation="NISRTVGWFTAQYPVVL"
     CDS_motif       complement(7292..7357)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg22_4_0003"
                     /evalue="3.50E-12"
                     /label="NRPS-E2"
                     /locus_tag="ctg22_4"
                     /protein_end="231"
                     /protein_start="209"
                     /score="38.4"
                     /tool="antismash"
                     /translation="LLIAVHHLVVDGVSWRILLEDF"
     CDS_motif       complement(7562..7627)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg22_4_0002"
                     /evalue="4.30E-05"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg22_4"
                     /protein_end="141"
                     /protein_start="119"
                     /score="15.9"
                     /tool="antismash"
                     /translation="ERVEKTLQALIEHHDALRMVYR"
     CDS_motif       complement(7697..7726)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg22_4_0001"
                     /evalue="3.30E-05"
                     /label="NRPS-E1"
                     /locus_tag="ctg22_4"
                     /protein_end="96"
                     /protein_start="86"
                     /score="16.5"
                     /tool="antismash"
                     /translation="LTPIQRWFFE"
     aSDomain        complement(7772..7975)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg22_4_PCP.1"
                     /evalue="2.70E-28"
                     /label="ctg22_4_PCP.1"
                     /locus_tag="ctg22_4"
                     /protein_end="71"
                     /protein_start="3"
                     /score="89.9"
                     /tool="antismash"
                     /translation="EELLAGIWQDVLGMSEVGVTDNFFSLGGDSIKGIQMASRLNQHGW
                     KLEMKDLFQHPTIEELTQYVERA"
ORIGIN
        1 tcggcagaaa gtgattactc gacatgtatg ggaagatcat aaagaaaagg tcagacaaaa
       61 tcgcttgtct gtttcaggaa aaaacctcta caaaaaaaga aaagaaaaca tagagcgaag
      121 ctttgcagat tcaaaacagc tgcatgggct tcgctattgc aggttgaggg gaaaacgaaa
      181 tgtgagtgaa caagttctcc tcacagccgc atgccagaac atgaagaaga ttgccacata
      241 cctagccaag cagggctagg catgtgggag cgctttttct gcatctgaaa cctgatgaat
      301 atctaaagaa actgtataaa acaaaaaagc ttgtagaaaa aacgtcgttt tctctacaag
      361 ctgaggatca gcattgacag tgctgatcct tttatattga ttggtgggtt tcttttgcct
      421 tttgtttatc taaaaacggc accagctcta ttacagccga taaacccaca aacacgatgc
      481 acacagcgac aatcagcaaa taaccatgag tcatgtcaaa aaacaaaccg cccgcataca
      541 cgctgagagc tccggcaacc tgatggataa agaaattgat gcctaacagc gatccgatca
      601 atcctgtttg atagctttcc gaaattgacg ccgcggtcag cgggatcacg cctgtgtaac
      661 tgagcccgaa taacaggata aacccgaagt accaaaggtc gctgtgatga attccgagaa
      721 tgggaatgag caggcaaatg aggctgagca gccgaatgaa aaataagatg gatagcatga
      781 cgcttctgct gccgaggaga tcggacagcc agcctgccaa taatccgcca atgataataa
      841 acgccccgaa cgcggccatc attccgttga catgagagac atgtgcatcc ttcagcatcg
      901 gaacgagatg agcatcaatg attcccatcg taaatccgca agtacacacg ccgaagtaca
      961 ggatatgaat gaggcgggat tgcttcatca cgttccaaaa cccccgccaa tcataagatt
     1021 ttttcacaga ctccgcttgc gcatacggcg ggtgcttcat cccaatgacg aagagcggca
     1081 gcagaacagc cgccatgacg attcccaaaa tcgtataggt gctctgccag ccggcatgat
     1141 acggagcctc agcccaaatg ggcgagagaa gcagcaggcc cgcagagttg gcattggtca
     1201 aaatagcaag cgccagacct ttgtgtgtgt caaaccaacg gctgatgaaa tactgggtcg
     1261 tcacgccgac cgcgcaggaa tagccgattc cgccaagcac accgtaaatg gcggaaaaca
     1321 catgaacatt cggtgaataa ggaagcacca aaaagcttgc gctgatgcaa acagctccaa
     1381 gcgccataat ttttctgaca ctgaaacggt cgatgaaaaa accgacaaaa aactggacga
     1441 tgccggttgt gatcataaaa atgctgacag aaaccgaaat cagcgacctg tcggcatgga
     1501 aggcatccgc cattggcagc ataaaaaatt gaaaggaatt tctgaatgag ttcattccga
     1561 tggcgaaaac aaacgtaaac agcaatacaa accatttcat cctgggagac gtgcgcatgt
     1621 ttcgacctgc ctttatttga gtatttcgac tattatacca tgcgaaaatt ggcattcaac
     1681 acaaaaaaaa gcggaacagc cgaagctgtc cgcttttgat cacggttgaa tgatcggatg
     1741 ctgattcaag atcgcaaaaa tccgttctgc gacttcttcc gtttgtgaca gcaggaacat
     1801 gtgtcctccg tcaaattgat ggaatgtgat gtcttttgcc cacttcttcc agccttccgc
     1861 atctcgtatg cattttttat catcaagccc gttaaagaca tgaacaggcg actggatctg
     1921 ggccagatcg taaagctcaa attgttcaag agcccggtaa tctgatcgga aagaaggcag
     1981 gaaaaaggac atgacctcct tattttcaac aagctctgcg ggcattccgc ctaattggat
     2041 aatatgatcg agaaactgat catcaggcag gtgggacact ttcttccgct gaatatgagg
     2101 cggctggatt gcagaaatga taaccgcctg cggaaagatg ccctcacgct caagcttttg
     2161 cgccagcctg aaggtgatca ttccgcccat actgtgtccg aacagcacaa acggccgatc
     2221 agggcgaagg ttcagttctt gcttgtacaa atctgtcagc tcttcgagat cctcaatggc
     2281 tgacgtttga ttcgtgccgt gtcccggcgg ctcggcagcg agcatctcgc actccccctg
     2341 caaaaaagca tggagagggc gaaacgacgc cgagtagccg ccagcaaacg gaaaacagat
     2401 gagctgcgtt ttttccgacg catcaaatga tttgaagagt tggctcattg gctgtctcct
     2461 cctttcatca cttcttttat gaaaccgtta cggtttgtgt attaagaaat tcgagcaaaa
     2521 tctccgcatt cctatctagc gtttcgccct gcagcatttc tgcgtgtgtt ccgaagcctc
     2581 ttttcatacg gtaagcaccc gttgtagctt cttcccatga tgcaagccat tccggcatgt
     2641 caaaatcagc gccggaagtc agcagatcaa tatctgcttt cacctggcct gtgctgatca
     2701 ggttgacgta gtatgagtaa aaggcatgtg ttttttgctt gaggccttgt ttgacggctt
     2761 cgctgttgag cgcttcattg tcccgattga cattcatcaa cgcttcgaca tcactttcaa
     2821 ccgtgcgtcc gtccagatca ctgacacctt gttttttata ggaatcgacc atgatgatcc
     2881 gctgaacaat acggccttgt ccctcaagct ttttcgcagc ttcaaacgcc aggctgcatc
     2941 ccgctgaata tccaaacaat gttaaaggcc cttccggctg cagcttctgg atcaaatccg
     3001 catagcggtc aagccggtct tcctcctcaa taaaatcaaa ggcgcacagc ttgtatgacg
     3061 gcaagcggct ggacagattt tggtacataa ggccatagcc caagatcggc gggaatgcga
     3121 aaatgatctg ctcctgatcc tgattcatta tcgttacatc ctgcaagcca tcgggacccc
     3181 cgtttttcac atacgctgaa atgccggcga tcgtcggcgc ttcaaacaaa agctttactg
     3241 gaagatcaat cccgagctct ttcttgatgc gggaagcggc ggtcattgcc tttaaggaat
     3301 gccctccgag cgcaaagaaa tcgtcatgaa tgccaatttg ctttctgccg agaacctcag
     3361 accatatttg tgcgattgtt tcttccatct cgttccgcgg tccaatccat tcttccgcca
     3421 gctgatcctg atcaggtttt gggagcagcc gtttattgac tttcccgttc gtcgttaaag
     3481 gaatctcatc caagaaggta aaggtttgcg gcaccatgta agcaggaagc tgttttttca
     3541 ggtgcgcctt cacgtcttca gctgaaagct gcgttcggtt cacaaggtag gcattgattg
     3601 atgcatcgcc agactcaggg cggtccgcca caacgaccgc atctttcaca cctgggtatt
     3661 cctgcagctg cttttcgatt tcttcaagct caatccggtg tccacgtatt ttgacctggt
     3721 cgtcaatacg gccggcgtat tcaatcgttc catccggcag ccagcgcgct aaatcccctg
     3781 tgcggtaaag cgtttctccc ggcttgaacg ggttcttaat aaacttttcc ttcgtgaggt
     3841 cagcacgatt tacatatcct tttgacacgc ccattccgct gatgcacagt tcaccgatcg
     3901 ccccgaatgg ctggagctgg ctttgctcgt tcagaatata aacactggca ttgctgatcg
     3961 gctttccgat cggcaatgag gagatggaat ccggtatatc atgcacgacg tgagcagtcg
     4021 caaacactgt tccctcagtc ggcccgtagc agttaatcag cttgcccggc cccatgaccc
     4081 gcagcgcttt tctgacatga ggcactgacg cgcgctctcc gccgaataat atacagcgta
     4141 gtcccttcat ccaatcctct cccgcatccg tgagaagatt aaatagtgcg gttgtcgcaa
     4201 acatgacatt gacattctct tgcaggatca gatctgtgag ccgttctgta tcaagcagcg
     4261 tatgttcatc tgcgataatg agccgtgccg cattcagcat agaagcatag aaatcaaagg
     4321 taaatgcgtc aaaggcgtaa ttggaaacag ataagaatgt atctttctca gagaatgcca
     4381 tgtagtctac atgcttgacc aatccttgaa tattggcatg agtggtgata ttgccctttg
     4441 gctttccggt tgtgccggac gtgtacatga tatatgccgg atcattagga tcaatcgcgg
     4501 ttgcaggatc gcttgcctgt tcttcaaacc gtgtttgatc atcaatgaag agcgttgtgc
     4561 ctgtatacgg cagctcagcc gcttgttctt tcatcttctg atgcgtcaga agacaggctg
     4621 ccgcactgtc agccagcata tacgagattc ggtcctctgg cagcttcgga tcaaccggca
     4681 gataggctgc tcccgccttt aatacaccga gaatgccgat taccagttca agtgagcgct
     4741 tcgtgtacag cgctacaaca gagcctttgc ccgcaccgtg tttttgcagc cggcgtgcaa
     4801 ggcggttcgc ttcctcatct aattcgcgat aagacagggt ctggccggaa tacgtaagcg
     4861 ccggcgcatc tggattgacg ttcactgctt ccttgaacca atccgtcaga ggctttgtat
     4921 catgagcttg agccggcggg tttaagccgg ttagcaaaaa ttctctctcc ctgtcgtcaa
     4981 cgaggttgat cgtgctgaca ggctgatccg gattctggat gagctgctga attgctgtga
     5041 gaagctgaga tttcaagcgc aggataaacg cctcatcaaa cacattctca ttataggcaa
     5101 acttaatcag catctcatct ccaggggaag ccatcaggtt gagatcataa ttcgacttct
     5161 caaaaacatg aacatccacc atatcaaagc cgttttcact gctttcttca tttttcgcat
     5221 cctgaagcgg atagttctca aaaacaatga tgtggtcaat cagtttcggc tgatcggcct
     5281 ggctttggat gtcataaagc ggcacatatt gatgcggctc agactgcagc gattgctcct
     5341 gcagctgctt gagcaagccg ttaaatgtga taccctcaga cagcttcaca cgtctcggga
     5401 caacgttgat aaacagcccg accatatgtt caacgccttt gatttccgcg ggacgccctg
     5461 aaacaactgt accgaaggtc aaatcgccag actgctgata gcggctgatc aatacgctcc
     5521 agactgcctg cagcgccgta cttaaagtgg tatgctgcga ttttgcaagc tcggtaaaag
     5581 cctttgtttc cgcctccggc agtgaaaaga gcagctcttt cggctcatag ccgtcctttt
     5641 gtttctttct ttgctccgca aacgtcgttt gtccttcaaa gtcctctaaa tactcgcgcc
     5701 agtaacgcag tgatgcttgt ttatcctgct tttcaagcca cttgatgtag tctttatacg
     5761 gtttgacggg cggcaggctg tacggctttt gttcgcgcag agcattgtat accttaaata
     5821 gatcctgtac gacgatgccg aagcaccatc cgtccaaaat aatgtggtgg tagctccaca
     5881 cccattcaaa gctttcttca gcttttttga aaatggctgc ccgcatcgga atatcccgcg
     5941 tcaaatcaaa acccctgatc ttatcctgtt ctttgtactc attgattttg gctgtttgct
     6001 cgctgcccgt taagtgtgtc agatcgattt cttctatatg gaactgccgt tttttcaata
     6061 cgacttggac aggccttttt actttttcgt aaatgaacac ggtacgaaat acatcgtacc
     6121 ggtccatgat cacattcatg ctttcttcaa gacatttgat attcaagctg ccttttactt
     6181 tcatcgtgat ttgttcaagg taaaagcttt ggccgggatt caggatggca tgaaaaagca
     6241 tcccttcctg catcggcgat aggtaataca tatcttgaac ctgatccttg ctaaattgac
     6301 tcatatgttt cgctcccgcc ttctgtaatt cccttgcgtt ttattttaaa ttctcctcaa
     6361 gcatgtcaaa gatatctccc atctcgtcca tttcaaggtc ttcggcgctg aagtcgcttg
     6421 gtgtgaattc cttgtcttct ttttccgtgc aatggcgaat tagcatcagg aggttttctt
     6481 taaaccgttc cattcgctct tcaatcgtgg ctctttcaaa ctccttttca ttgtaggagc
     6541 aggaaagcac aaaccggccg tttctgatca tgccgctgaa gcttaatgcg tacagcgcct
     6601 ctgattcctc gcttacttgg cgccccatat cgaatgcgga cggttcaaag aaatcggttt
     6661 tgacttcgct gtcgaattgg cccaaatagt tgaagctgat ctccggtgtg aagccctttg
     6721 tttccgctgt ttctgtgaaa taacgaagaa tgccgtagcc aacacctttg tccggaatgc
     6781 ggcgcaggtt ttctttgact gttttgatca cagctgaggc atctgcttca gatatgtcga
     6841 gcacaacagg gtattgtgcc gtaaaccagc cgaccgttct ggagatattc acattcggga
     6901 taatatcctc ccggccgtgt ccctcaaggt taatgccaat tttggcaccc tttgtccatt
     6961 ctttcattgt caaaccgagc gcgctgagaa gaatatcgtt gatttcagta ccatatggct
     7021 gatgaacatc tgttaaaaga tgcttcgtgt cttcttccgt taattcacat aggacggatg
     7081 atgtatcctt gacgatccgc tgctctgttt cacaatcctt cggtaaagga gaaacctgtt
     7141 cagcggcaat ttgcgaccag tattcagcct gctgtaaaag atgcgctgat tggctgaatg
     7201 ccgccagttc ttccgcccag tccttgaagg agtttgtttt ttgcgggaag acaaggctct
     7261 cttctttctc agcctgcatg tagcctgaag caaagtcttc aagcaaaatc cgccatgaca
     7321 caccgtcgac cacgagatgg tgtacagcaa tgagcaggtg atccccagct tctgtgcgat
     7381 attgctccgc ctttaaaagc ggcccggttc tcagatcgag actgctttgc agcttgttcg
     7441 cgagaatctt aatctggctt ctcagcatct cttcatcaga gccgtacaga tccacgattt
     7501 cgaagctgac cttgctctca ccgatcggtt tatacgcctg aacgatgtcc ccgttttcct
     7561 cacgatagac catacggagc gcgtcatgat gctcgatcag cgcctgcaat gttttctcca
     7621 cccgttcagg accaaagccc tttttggcgt gaagcatcac agattggttc cagtggtgct
     7681 tgttcgtgaa gttcttttca aagaaccagc gctggatcgg cgtcaggatg acttcgccct
     7741 ccaccgggcc ttggtctgcc tgtttgcctt cggcacgctc tacatattgg gtaagctctt
     7801 cgatcgtcgg gtgctggaag agatctttca tttccagctt ccagccgtgc tggttcaagc
     7861 ggctcgccat ttgaattcct ttgatggaat ctccgccaag cgagaagaaa ttgtcggtga
     7921 caccgacttc agacattcca agcacgtcct gccagatgcc ggcaagcagc tcttccatgt
     7981 cgggcg
//
