LOCUS gnlProkkaCJMLLOPC_18 27685 bp DNA linear UNK 01-JAN-1980 DEFINITION gnl|Prokka|CJMLLOPC_18. ACCESSION gnlProkkaCJMLLOPC_18 VERSION gnlProkkaCJMLLOPC_18 KEYWORDS . SOURCE ORGANISM . COMMENT ##antiSMASH-Data-START## Version :: 7.1.0 Run date :: 2025-04-28 19:10:31 Original ID :: gnl|Prokka|CJMLLOPC_18 NOTE: This is a single region extracted from a larger record! Orig. start :: 18088 Orig. end :: 45773 ##antiSMASH-Data-END## FEATURES Location/Qualifiers protocluster 1..27685 /aStool="rule-based-clusters" /category="NRPS" /contig_edge="True" /core_location="[20000:27683]" /cutoff="20000" /detection_rule="cds(Condensation and (AMP-binding or A-OX))" /neighbourhood="20000" /product="NRPS" /protocluster_number="1" /tool="antismash" proto_core 20001..27683 /aStool="rule-based-clusters" /tool="antismash" /cutoff="20000" /detection_rule="cds(Condensation and (AMP-binding or A-OX))" /neighbourhood="20000" /product="NRPS" /protocluster_number="1" cand_cluster 1..27685 /SMILES="NC(CCC(=O)N)C(=O)NC(CC(C)C)C(=O)O" /candidate_cluster_number="1" /contig_edge="True" /detection_rules="cds(Condensation and (AMP-binding or A-OX))" /kind="single" /product="NRPS" /protoclusters="1" /tool="antismash" region 1..27685 /candidate_cluster_numbers="1" /contig_edge="True" /product="NRPS" /region_number="1" /rules="cds(Condensation and (AMP-binding or A-OX))" /tool="antismash" CDS complement(1973..4288) /gene_functions="biosynthetic-additional (rule-based-clusters) Pyr_redox_2" /gene_functions="biosynthetic-additional (rule-based-clusters) Fer2_BFD" /gene_functions="biosynthetic-additional (smcogs) SMCOG1175:pyridine nucleotide-disulfide oxidoreductase (Score: 146.8; E-value: 1.2e-44)" /gene_kind="biosynthetic-additional" /locus_tag="ctg18_18" /sec_met_domain="Pyr_redox_2 (E-value: 4.7e-59, bitscore: 191.4, seeds: 64, tool: rule-based-clusters)" /sec_met_domain="Fer2_BFD (E-value: 1.9e-17, bitscore: 55.0, seeds: 211, tool: rule-based-clusters)" /transl_table=11 /translation="MKKQRLVLAGNGMAGIRCIEEVLKLNRHMFEIVIFGSEPHPNYNR ILLSSVLQGEASLDDITLNSKDWYDKHGITLYTGETVIQIDTDQQQVITDRKRTLSYDK LIVATGSSPHILPIPGADKKGVYGFRTIEDCQALMNMAQHFQKAAVIGAGLLGLEAAVG LQHLGMDVSVIHHSAGIMQKQLDQTAARLLQTELEQKGLTFLLEKDTVSISGATKADRI HFKDGSSLKADLIVMAAGVKPNIELAVSAGIKVNRGIIVNDFMQTSEPNIYAVGECAEH NGTVYGLVAPLYEQGKALASHICGVPCEEYQGSAPSAALKIAGIDVWSAGKIQEDERTT SIKIYDEQAGVYKKALFVDEKLAGVILFGDTRDKQRLLDSLLKQRDISIVKKQIIEPET SGPLFESMPSSETICQCNTVTKGAIEEAVHTNSLTTVEEVKHCTKATGSCGGCKPLVED LLRHMTNSEYTKPAGTPSFCSCTDFTEDDIIAELQRRPFTNPAEVMNQLDWKTKNGCST CVPAIQYYLEMLYPGFVQPEPATEETCILIPQMYGGRTNAEQLRTIANIIEAYSIPDVS ITHGQRLKLSGIKPADLPNIKKDLKMPVYTNEHRHALQSIKACTCGQNRSIQQLAAQIE RQLEMLPLPAPISISLSCETDCTDAALQDVGAIRRQAGWDIHIGGVRGTHARSGALFCV TENEDSTAGMIKGLIQYYRETAHYLEGVHQWIDRLGIVHIREVLFEEDLRAQLLESLQT DLSLIQNPTVETGAYKKG" CDS 4468..5673 /gene_functions="transport (smcogs) SMCOG1106:major facilitator transporter (Score: 127.6; E-value: 8.1e-39)" /gene_kind="transport" /locus_tag="ctg18_19" /transl_table=11 /translation="MKLSELKTSGHPLTLLCSFLYFDVSFMIWVMLGALGVYISQDFGL SPFEKGLVVAVPILSGSVFRIILGILTDRIGPKKTAVIGMLVTMIPLLWGTFGGRSLTE LYAIGILLGVAGASFAVALPMASRWYPPHLQGLAMGIAGAGNSGTLFATLFGPRLAEQF GWHIVMGIALIPLLIVFILFVSMAKDSPAQPSPQPLKSYLHVFGQKETWFFCLLYSVTF GGFVGLSSFLSIFFVDQYQLSKIHAGDFVTLCVAAGSFFRPVGGLISDRVGGTKVLSVL FVIVALCMAGVSSLPSLSMVIVLLFVGMMGLGMGNGAVFQLVPQRFRKEIGMVTGIVGA AGGIGGFFLPNILGSLKQMTGTYAIGFITFSCIALLAFALVLAAGYYWRKSWSAESSPA DV" CDS 6547..7131 /locus_tag="ctg18_20" /transl_table=11 /translation="MKLSLFIIAVLMPACLLSTCSEHAEEHASINTKKTVENITDVRKT AKISIDWTKPSGGEYPDIKQKHVWIDVNVKEQKAYIKEGSNTIYTMMISSGLDQTKDDA TPKGTFYVEPERGEWFFSEGYQEGAEYWVSWKNHGEFLFHSVPMTKDQKVIKTEAEKLG TKASHGCIRLTIPDAKWIYENIPEHTKVVIS" CDS 7570..8253 /gene_functions="biosynthetic-additional (smcogs) SMCOG1178:cobalamin synthesis protein/P47K family protein (Score: 276.1; E-value: 7.1e-84)" /gene_kind="biosynthetic-additional" /locus_tag="ctg18_21" /transl_table=11 /translation="MKKIPVTVLSGYLGAGKTTLLNSILQNREGLKIAVIVNDMSEVNI DAGLVKQEGGLSRTDEKLVEMSNGCICCTLREDLLIEVEKLAKDGRFDYIVIESTGISE PIPVAQTFSYIDEEMGIDLTKFCQLDTMVTVVDANRFWHDYQSGESLLERKEALGEEDE REIADLLIDQIEFCDVLILNKCDLVSEQELEQLENVLRKLQPRAKFIRCQRKCKTAGDF AYRVI" CDS 8234..8761 /gene_functions="biosynthetic-additional (smcogs) SMCOG1178:cobalamin synthesis protein/P47K family protein (Score: 105.3; E-value: 6.5e-32)" /gene_kind="biosynthetic-additional" /locus_tag="ctg18_22" /transl_table=11 /translation="MHTGLFNFEEASGSAGWIQELTAGHAEHTPETEEYGISSFVYKRR LPFHSTRFYQWIDQMPKNVVRAKGIVWCASHNNLALLMSQAGPSVTIEPVSYWVAALPK LEQEQVKQQEPEILEEWDPEFGDRLTQLVFIGTDLDEETITKELDQCLLTEYEFDSDWS LFEDPFKWKLNQ" CDS complement(8810..9490) /gene_functions="transport (smcogs) SMCOG1096:polar amino acid ABC transporter, inner membrane (Score: 242.2; E-value: 8e-74)" /gene_kind="transport" /locus_tag="ctg18_23" /transl_table=11 /translation="MINSIQWEYIFNTKLVIESFPYVIKGIGYTLLISFVSMFAGTVIG LFISLARMSKLALLRWPAKLYISFMRGVPILVILFILYFGFPYISIQFSAVTAALIGFS LNSAAYIAEINRSAISSVEKGQWEAASSLGLSYWQTMRGIILPQSIHIALPPLANVLLD LIKASSLAAMITVPELLQHAKIIGGREFDYMTMYILTALIYWAICSIAAVFQNILEKKY AHYV" CDS complement(9500..10084) /gene_functions="biosynthetic-additional (smcogs) SMCOG1091:glutamine-binding lipoprotein glnH (Score: 146.1; E-value: 1.6e-44)" /gene_kind="biosynthetic-additional" /locus_tag="ctg18_24" /transl_table=11 /translation="MGIDGMLTAVNSGQVDAAANDIDVTKDREKKFAFSTPYKYSYGTA IVRKDDLSGIKTLKDLKGKKAAGAATTVYMEVARKYGAKEVIYDNATNEQYLKDVANGR TDVILNDYYLQTLALAAFPDLNITIHPDIKYMPNKQALVMKKSNEALQKKMNEALKEMS KDGSLTKLSKQFFNKADVSKKIDADVQDVDL" CDS 10741..11196 /locus_tag="ctg18_25" /transl_table=11 /translation="MNIYKPAGFWIRLGAALLDYIIVSVPLLLIYWLITGKDPNDSMFI SLVVLLYSILLPVFWHGYLIGKRICGIRIVKKEGSQVSLLTMFLRVIVAGLVYFITFGL GLIASLILIAVREDKRTLHDLIAGTYVTYATPGEEELNTDEEIRKSE" CDS 11278..11610 /locus_tag="ctg18_26" /transl_table=11 /translation="MKRITINIITMFIATTVISLTGTAEAAEKQQQPPANVTLTDQQKK EVEQLEAEILKKRKDVISKYVQYGVLPKERGEHIKNHLDKHFEMMKQNGFVPKHHPHPH KFEKRH" CDS 11735..12160 /gene_functions="regulatory (smcogs) SMCOG1135:MarR family transcriptional regulator (Score: 76.4; E-value: 2.6e-23)" /gene_kind="regulatory" /locus_tag="ctg18_27" /transl_table=11 /translation="MMEMDLISKLNQQWTDIYYLLHYQHKDNISHQAIRIMQHIEKQGE VTIGALAEYLSVSHNTASEHTKRLIQKGFIAKRRSQQDERKVLVFLTQEGRSVLEQHTQ LDKEKLKEIIERMSTSEKQLLEQAFELLSREAKQWQF" CDS 12148..12468 /locus_tag="ctg18_28" /transl_table=11 /translation="MAVLSKVIISALIIGFVTEISKRHPTYGGIIAALPLVSLLSLFWM QIQSQFASGVLTGIPATVCLLAILAFLLKIHVPFWFALCVGILGWAMFLWMQKIFLNIL FN" CDS 12487..13107 /locus_tag="ctg18_29" /transl_table=11 /translation="MFLKKVTLLRDKILDFDRFPFTIPAISQLNDILFTSQVTFFVGEN GSGKSTLLEAIADKCEFNTAGGSRNNVYELRESDSHLGDYIRLSWLPKVTNGFFLRAES FYHLSLHLDEMELDAPQPYRSYGGRPLHNQSHGESFMSLFRHRFKEKAIYLLDEPEAAL SPARQLAFLRVIHDLVKGGIGEGRKCTDDHCDSLPNPTGLSQC" CDS 13058..13231 /locus_tag="ctg18_30" /transl_table=11 /translation="MIIATHSPILLGYPNANILSFDGGRIHHIEYENTEHVQLTRYFLG QREKILAELFRD" CDS 13304..13507 /locus_tag="ctg18_31" /transl_table=11 /translation="MIHQHPESFPKHFLWGSASAAYQIEGAWIEDGKGPSVWYVFTKIP GKTFKGTNGDIAIITDLKKMSL" CDS 13507..14445 /locus_tag="ctg18_32" /transl_table=11 /translation="MAEMGLKAYRFSVSWPRVFPKGKGEINEAGLAFYDSLIDELISHH IEPVLTLYHWDLPQALMDEYGGFESRNIIEDFNHYCITLYKRFGDRVKYWVTLNEQNYN FNHGFITAMHPPGVKDRKRFYEANHIAFLANAKAIESFREYVPEGKIGPSFAYSPAYPL SSHPEDILAFENAEEFTNNWWLDMYCWGTYPQIPFRYLEKQGWAPTIEAGDMDLLAKGK PDFVGVNYYQTITYERNPLDGVSEGKMNTTGQKGTNQETGIPGVFKTKKNPHLTTSNWD WTIDPIGLRIGLRRITSRYQLPVFINRERFG" CDS 14438..14731 /locus_tag="ctg18_33" /transl_table=11 /translation="MGEFDKVEDGTVQDDYRIDYLRSHLEQCRQAISDGVDLIGYCSWS FTDLLSWLNGYQKRYGFVYVNRDEESTYDLKRLKKKSFYWYQDVIKTNGESL" CDS complement(14768..15166) /locus_tag="ctg18_34" /transl_table=11 /translation="MIKSWKPQELSISYHQFTVFQKDSTPPIMDWTDEAIEKGYTAADG AISFEAQRNTKAFILLRLNSSETVNSYEKKVTVPFHVTENGIHIESIMSKRLSFDLPKG DYQLTCWTVPAEMSDLHADTYIIDAVSV" CDS complement(15193..15642) /locus_tag="ctg18_35" /transl_table=11 /translation="MNITTDIIKTILLVIVIIAAAAVGLIKGDFFSADQKTSQTKEYDE TIAFPSDRYPETAKHIKDAINEGHSEVCTIDRDGAEERREQSLKDVPSKKGYDRDEWPM AMCKEGGEGASVEYISPADNRGAGSWVGHQLTDYPDGTKVLFTIQ" CDS complement(15810..16460) /gene_functions="other (smcogs) SMCOG1061:methyl-accepting chemotaxis protein (Score: 218.1; E-value: 4e-66)" /gene_kind="other" /locus_tag="ctg18_36" /transl_table=11 /translation="MDAIHQSIQKSGEIIHQLDGRSKQIEQILSVITQIADQTNLLALN AAIEAARAGEQGKGFAVVADEVRKLAEESQQSAGQISKLIIEIQKDMNRSARSVEHVKT EAAEGVTMIQRTRDAFKEIAAATGEISAEISDLSASVTNISASAHHINHSFAANTADIK ESTKNTRQAAALTEEQFAAMEEITAASETLSQLAEELTGIISQFKMINQAENG" CDS complement(16641..17531) /gene_functions="other (smcogs) SMCOG1061:methyl-accepting chemotaxis protein (Score: 67.8; E-value: 1.3e-20)" /gene_kind="other" /locus_tag="ctg18_37" /transl_table=11 /translation="MLIKRFKMKLGTKILCLVFVVILLFSASVGTVMLKEITENMKQMA TEKAKGDLALSSTYIDDVISGDWQVKNNKLYKGQTQINGNEELVDLLGEKTGDTITIFQ GDTRVATNVMKNGERAVGTQASSEVIAAVLKKGKCFYGQADVAGSSYQTAYMPLKDQNG SIIGMLYTGANQSILASLTQSLFTQFAIVLVIVIMLSVILVLVFTRKINKRLNALKSAF ESAGNGDMTIEVSDKTGDELSELSVYYNKMRMKLNDTIQTVQQSALQLASASQQLSAGA EETNQASEKITEAVQ" CDS complement(17641..18198) /locus_tag="ctg18_38" /transl_table=11 /translation="MKTTEYVAEILNELHNSAAYISNEEADQLADHILSSHQIFTAGAG RSGLMAKSFAMRLMHMGFNAHIVGEILTPPLAEGDLVIIGSGSGETKSLIHTAAKAKSL HGIVAALTINPESSVGKQADLIIRMPGSPKDPSNGSYKTIQPMGSLFEQTLLLFYDAVI LKLMEKKGLDSETMFTHHANLE" CDS complement(18204..18836) /locus_tag="ctg18_39" /transl_table=11 /translation="MELQLALDLVNIPEAIELVKEVEQYIDVVEIGTPVVINEGLRAVK EIKEAFPQLKVLADLKIMDAGGYEIMKASEAGADIITVLGATDDATIKGAVEEAKKQKK KILVDMINVKDIESRAKEIDALGVDYICVHTGYDLQAEGKNSFEELTTIKNTVKNAKTA IAGGIKLDTLPEVIKQNPDLVIVGGGITSAADKAETASKMKQLIVQG" CDS 18975..19427 /gene_functions="regulatory (smcogs) SMCOG1167:transcriptional regulator (Score: 117.5; E-value: 2.5e-36)" /gene_kind="regulatory" /locus_tag="ctg18_40" /transl_table=11 /translation="MSEYNEKRVCKKVSDDTYLTYKKVTKGGILLSRMDDKRFNCEKEL TLAVIGGKWKMLILWHLGKEGTKRFNELKTLIPDITQKILVNQLRELEQDMIVHREVYP VVPPKVEYSLTPHGESLMPILEAMYEWGKGYMELIDIDKNVMKESL" CDS complement(19408..19668) /locus_tag="ctg18_41" /transl_table=11 /translation="MGEKFHAGCRKIPVYLQGYFCGMPQSFPLNIIYRKIKIFKPNCCV QSFFIAECNLQSLHDYVYRAKTEKKAKKRHPCEERLTTILS" CDS 20001..27683 /NRPS_PKS="Domain: Condensation_Starter (4-303). E-value: 4.1e-98. Score: 320.2. Matches aSDomain: nrpspksdomains_ctg18_42_Condensation_Starter.1" /NRPS_PKS="Domain: AMP-binding (466-867). E-value: 6.7e-113. Score: 369.2. Matches aSDomain: nrpspksdomains_ctg18_42_AMP-binding.1" /NRPS_PKS="Domain: PCP (976-1044). E-value: 4.4e-24. Score: 76.4. Matches aSDomain: nrpspksdomains_ctg18_42_PCP.1" /NRPS_PKS="Domain: Condensation_LCL (1058-1345). E-value: 2.4e-106. Score: 346.9. Matches aSDomain: nrpspksdomains_ctg18_42_Condensation_LCL.1" /NRPS_PKS="Domain: AMP-binding (1510-1908). E-value: 1.7e-109. Score: 358.0. Matches aSDomain: nrpspksdomains_ctg18_42_AMP-binding.2" /NRPS_PKS="Domain: PCP (2015-2084). E-value: 5.3e-30. Score: 95.3. Matches aSDomain: nrpspksdomains_ctg18_42_PCP.2" /NRPS_PKS="Domain: Condensation_LCL (2098-2384). E-value: 9.4e-109. Score: 354.8. Matches aSDomain: nrpspksdomains_ctg18_42_Condensation_LCL.2" /gene_functions="biosynthetic (rule-based-clusters) NRPS: Condensation" /gene_functions="biosynthetic (rule-based-clusters) NRPS: AMP-binding" /gene_functions="biosynthetic-additional (rule-based-clusters) PP-binding" /gene_functions="biosynthetic-additional (smcogs) SMCOG1002:AMP-dependent synthetase and ligase (Score: 370.7; E-value: 1.6e-112)" /gene_kind="biosynthetic" /locus_tag="ctg18_42" /sec_met_domain="AMP-binding (E-value: 5.9e-122, bitscore: 398.6, seeds: 400, tool: rule-based-clusters)" /sec_met_domain="PP-binding (E-value: 1.7e-15, bitscore: 48.8, seeds: 164, tool: rule-based-clusters)" /sec_met_domain="Condensation (E-value: 3.1e-99, bitscore: 323.2, seeds: 42, tool: rule-based-clusters)" /transl_table=11 /translation="MEITFYPLTDAQKRIWYTEKFYPHTSISNLAGIGKLVSADAIDYV LVEQAIQEFIRRNDAMRLRLRLDENGEPVQYISEYRPVDIKHTDTTEDPNAIEFISQWS REETKKPLPLYDCDLFRFSLFTIKENEVWFYANVHHVISDGISMNILGNAIMHIYLELA SGSEAKEGISHSFIDHVLSEQDYAQSKRFEKDKAFWNKQFESVPELVSLKRNASAGGSL DAERFSKDVPEALHQQILSFCEANKVSVLSVFQSLLAAYLYRVSGQNDVVTGTFMGNRT NAKEKQMLGMFVSTVPLRTNIDGGQAFLEFVKDRMKDLMKTLRHQKYPYNLLINDLRET KSSLTKLFTVSLEYQVMQWQKEEDLAFLTEPIFSGSGLNDVSIHVKDRWDTGKLTIDFD YRTALFTSEEINMICERMITMLENALTHPEHTIDELTMISDAEKEKLLARAGGKSVSYR KDMTIPKLFQEKAEQLSDHPAVVFEDRTLSYRMLHEQSARIANVLKQKGVGPDSPVAVL IERSERMITAIMGILKAGGAYVPIDPGFPAERIQYILEDCGADFILTESKVAAPEADAE LIDLDQAIAEGAEESLNADVNARNLAYIIYTSGTTGRPKGVMIEHRQVHHLVESLQQTI YQSGSQPLRMALLAPFHFDASVQQIFASLLLGQTLYIVPKKTVTNGAALAAYYRRNSIE ATDGTPAHLQMLAAAGDFEGLKLKHMLIGGEGLSTVVADKLLKLFKEAGTAPRLTNVYG PTETCVDASVHPVIPENAVQSAYVPIGKALGNNRLYILDQKGRLQPEGVAGELYIAGDG VGRGYLHLPELTEEKFLQDPFVPGDRMYRTGDVVRWLPDGTIEYLGREDDQVKVRGYRI ELGEIEAVIQQAPDVAKAVVLARPDEQGNLEVCAYVVQKPGSEFAPAGLREHAARQLPD YMVPAYFTEVTEIPLTPSGKVDRRKLFALEVKAVSGTAYTAPRNETEKAIAAIWQDVLN VEKAGIFDNFFETGGHSLKAMTLLTKIHKETGIEIPLQFLFEHPTITALAEEADHRESK AFAVIEPAEKQEHYPLSLAQQRTYIVSQFEDAGVGYNMPAAAILEGPLDIQKLERAFQG LIRRHESLRTSFVLENSTPRQKIHDSVDFNIEMIERGGRSDEAIMASFVRTFDLAKAPL FRIGLLGLEENRHMLLFDMHHLISDGVSIGIMLEELARIYKGEQLPDLRLQYKDYAVWQ SRQAAEGYKKDQAYWKEVFAGELPVLQLLSDYPRPPVQSFEGDRVSIKLDAGVKDRLNR LAEQNGATLYMVMLSAYYTLLSKYTGQDDIIVGTPSAGRNHSDTEGIIGMFVNTLAIRS EVKQNETFTQLISRVRKRVLDAFSHQDYPFEWLVEDLNIPRDVSRHPLFDTMFSLQNAT EGIPAVGDLSLSVQETNFKIAKFDLTVQARETDEGIEIDVDYSTKLFKQSTADRLLTHF ARLLEDAAADPEKPISEYKLLSEEEAASQIQQFNPGRTPYPKDKTIVQLFEEQAANTPD HTALQYEGESLTYRELNERANRLARGILSLGAGEGRTAAVLCERSMDMIVSILAVLKSG SAYVPIDPEHPIQRMQHFFRDSGAKVLLTQRKLKALAEEAEFKGVIVLADEEESYHADA RNLALPLDSAAMANLTYTSGTTGTPKGNIVTHANILRTVKETNYLSITEQDTILGLSNY VFDAFMFDMFGSLLNGAKLVLIPKETVLDMARLSRVIERENISILMITTALFHLLVDLN PACLSTLRKIMFGGERASVEHVRKALQTVGKGKLLHMYGPSESTVFATYHPVDELEEHT LSVPIGKPVSNTEVYILDRTGHVQPAGIAGELCVSGEGLVKGYYNRPELTEEKFVPHPF TSGERMYKTGDLARWLPNGDIEFIGRIDHQVKIRGQRIELGEIEHQLQTHDRVQESVVL AVDQGAGDKLLCAYYVGEGDISSQEMREHAAKDLPAYMVPAVFIQMDELPLTGNGKIDR RALPIPDANVSRGVSYVAPRNEIEQKVADIWAQVLQAEQVGAYDHFFDIGGHSLAGMKM LALVHQELGVELSLKDLFQSPTVEGLAQVIASAEKGTAASISPAEKQDTYPVSSPQKRM YVLQQLEDAQTSYNMPAVLRLTGELDVERLNSVMQQLMQRHEALRTTFEIKDGETVQRI WEEAECEIAYFEAPEEETERIVSEFIKPFKIDQLPLFRIGLIKHSDTEHVLLFDMHHII SDGASVGVLIEELSKLYDGETLEPLRIQYKDYAVWQQQFIQSELYKKQEEHWLEELDGE LPVLTLPTDYSRPAVQTFEGDRIAFSLEAGKADALRRFAKETDSTLYMVLLASYSAFLS KLSGQDDIIVGSPVAGRSQADVSRVIGMFVNTLALRTYPKGEKTFADYLNEVKETALSA FDAQDYPLEDLIGNVLVQRDTSRNPLFDAVFSMQNANIKDLTMKGIQLEPHPFERKTAK FDLTLTADETDGGLTFVLEYNTALFKQETIERWKQYWMELLDAVTGNPNQPLSSLSLVT ETEKQALLEAWKGKALPVPTDKTVHQLFEETAQRHKDR" aSDomain 20013..20909 /aSDomain="Condensation" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg18_42_Condensation_Starter.1" /domain_subtypes="Condensation_Starter" /evalue="4.10E-98" /label="ctg18_42_Condensation_Starter.1" /locus_tag="ctg18_42" /protein_end="303" /protein_start="4" /score="320.2" /tool="antismash" /translation="FYPLTDAQKRIWYTEKFYPHTSISNLAGIGKLVSADAIDYVLVEQ AIQEFIRRNDAMRLRLRLDENGEPVQYISEYRPVDIKHTDTTEDPNAIEFISQWSREET KKPLPLYDCDLFRFSLFTIKENEVWFYANVHHVISDGISMNILGNAIMHIYLELASGSE AKEGISHSFIDHVLSEQDYAQSKRFEKDKAFWNKQFESVPELVSLKRNASAGGSLDAER FSKDVPEALHQQILSFCEANKVSVLSVFQSLLAAYLYRVSGQNDVVTGTFMGNRTNAKE KQMLGMFVSTVPLRTNID" aSModule 20013..23132 /complete /domains="nrpspksdomains_ctg18_42_Condensation_Starter.1" /domains="nrpspksdomains_ctg18_42_AMP-binding.1" /domains="nrpspksdomains_ctg18_42_PCP.1" /locus_tags="ctg18_42" /monomer_pairings="Gln -> Gln" /starter_module /tool="antismash" /type="nrps" CDS_motif 20016..20054 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg18_42_0001" /evalue="6.60E-03" /label="C1_starter_004-017" /locus_tag="ctg18_42" /protein_end="18" /protein_start="5" /score="9.5" /tool="antismash" /translation="YPLTDAQKRIWYT" CDS_motif 20079..20198 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg18_42_0002" /evalue="1.70E-06" /label="C2_starter_024-063" /locus_tag="ctg18_42" /protein_end="66" /protein_start="26" /score="20.7" /tool="antismash" /translation="ISNLAGIGKLVSADAIDYVLVEQAIQEFIRRNDAMRLRLR" CDS_motif 20412..20477 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg18_42_0003" /evalue="1.70E-06" /label="C3_LCL_132-143" /locus_tag="ctg18_42" /protein_end="159" /protein_start="137" /score="20.7" /tool="antismash" /translation="VHHVISDGISMNILGNAIMHIY" CDS_motif 20808..20897 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg18_42_0004" /evalue="9.30E-12" /label="C5_starter_265-294" /locus_tag="ctg18_42" /protein_end="299" /protein_start="269" /score="37.3" /tool="antismash" /translation="DVVTGTFMGNRTNAKEKQMLGMFVSTVPLR" CDS_motif 20949..21062 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg18_42_0005" /evalue="6.60E-10" /label="C67_starter_14fromHMM" /locus_tag="ctg18_42" /protein_end="354" /protein_start="316" /score="31.6" /tool="antismash" /translation="KDLMKTLRHQKYPYNLLINDLRETKSSLTKLFTVSLEY" aSDomain 21399..22601 /aSDomain="AMP-binding" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg18_42_AMP-binding.1" /evalue="6.70E-113" /label="ctg18_42_AMP-binding.1" /locus_tag="ctg18_42" /protein_end="867" /protein_start="466" /score="369.2" /specificity="substrate consensus: Gln" /tool="antismash" /translation="FQEKAEQLSDHPAVVFEDRTLSYRMLHEQSARIANVLKQKGVGPD SPVAVLIERSERMITAIMGILKAGGAYVPIDPGFPAERIQYILEDCGADFILTESKVAA PEADAELIDLDQAIAEGAEESLNADVNARNLAYIIYTSGTTGRPKGVMIEHRQVHHLVE SLQQTIYQSGSQPLRMALLAPFHFDASVQQIFASLLLGQTLYIVPKKTVTNGAALAAYY RRNSIEATDGTPAHLQMLAAAGDFEGLKLKHMLIGGEGLSTVVADKLLKLFKEAGTAPR LTNVYGPTETCVDASVHPVIPENAVQSAYVPIGKALGNNRLYILDQKGRLQPEGVAGEL YIAGDGVGRGYLHLPELTEEKFLQDPFVPGDRMYRTGDVVRWLPDGTIEYLGREDDQVK VR" CDS_motif 21585..21626 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg18_42_0006" /evalue="1.90E-05" /label="NRPS-A_a2" /locus_tag="ctg18_42" /protein_end="542" /protein_start="528" /score="17.8" /tool="antismash" /translation="MGILKAGGAYVPID" CDS_motif 21804..21863 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg18_42_0007" /evalue="7.40E-11" /label="NRPS-A_a3" /locus_tag="ctg18_42" /protein_end="621" /protein_start="601" /score="33.8" /tool="antismash" /translation="AYIIYTSGTTGRPKGVMIEH" CDS_motif 22254..22277 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg18_42_0008" /evalue="1.20E-01" /label="NRPS-A_a5" /locus_tag="ctg18_42" /protein_end="759" /protein_start="751" /score="5.7" /tool="antismash" /translation="YGPTETCV" CDS_motif 22395..22484 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg18_42_0009" /evalue="5.10E-15" /label="NRPS-A_a6" /locus_tag="ctg18_42" /protein_end="828" /protein_start="798" /score="47.6" /tool="antismash" /translation="PEGVAGELYIAGDGVGRGYLHLPELTEEKF" CDS_motif 22566..22631 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg18_42_0010" /evalue="3.70E-12" /label="NRPS-A_a8" /locus_tag="ctg18_42" /protein_end="877" /protein_start="855" /score="38.1" /tool="antismash" /translation="YLGREDDQVKVRGYRIELGEIE" aSDomain 22929..23132 /aSDomain="PCP" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg18_42_PCP.1" /evalue="4.40E-24" /label="ctg18_42_PCP.1" /locus_tag="ctg18_42" /protein_end="1044" /protein_start="976" /score="76.4" /tool="antismash" /translation="EKAIAAIWQDVLNVEKAGIFDNFFETGGHSLKAMTLLTKIHKETG IEIPLQFLFEHPTITALAEEADH" aSDomain 23175..24035 /aSDomain="Condensation" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg18_42_Condensation_LCL.1" /domain_subtypes="Condensation_LCL" /evalue="2.40E-106" /label="ctg18_42_Condensation_LCL.1" /locus_tag="ctg18_42" /protein_end="1345" /protein_start="1058" /score="346.9" /tool="antismash" /translation="QEHYPLSLAQQRTYIVSQFEDAGVGYNMPAAAILEGPLDIQKLER AFQGLIRRHESLRTSFVLENSTPRQKIHDSVDFNIEMIERGGRSDEAIMASFVRTFDLA KAPLFRIGLLGLEENRHMLLFDMHHLISDGVSIGIMLEELARIYKGEQLPDLRLQYKDY AVWQSRQAAEGYKKDQAYWKEVFAGELPVLQLLSDYPRPPVQSFEGDRVSIKLDAGVKD RLNRLAEQNGATLYMVMLSAYYTLLSKYTGQDDIIVGTPSAGRNHSDTEGIIGMFVNTL AIRSEV" aSModule 23175..26252 /complete /domains="nrpspksdomains_ctg18_42_Condensation_LCL.1" /domains="nrpspksdomains_ctg18_42_AMP-binding.2" /domains="nrpspksdomains_ctg18_42_PCP.2" /locus_tags="ctg18_42" /monomer_pairings="Leu -> Leu" /tool="antismash" /type="nrps" CDS_motif 23250..23360 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg18_42_0011" /evalue="4.20E-17" /label="C2_LCL_024-062" /locus_tag="ctg18_42" /protein_end="1120" /protein_start="1083" /score="54.5" /tool="antismash" /translation="YNMPAAAILEGPLDIQKLERAFQGLIRRHESLRTSFV" CDS_motif 23553..23618 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg18_42_0012" /evalue="1.60E-08" /label="C3_LCL_132-143" /locus_tag="ctg18_42" /protein_end="1206" /protein_start="1184" /score="27.0" /tool="antismash" /translation="MHHLISDGVSIGIMLEELARIY" CDS_motif 23649..23681 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg18_42_0013" /evalue="6.20E-04" /label="C4_LCL_164-176" /locus_tag="ctg18_42" /protein_end="1227" /protein_start="1216" /score="12.5" /tool="antismash" /translation="QYKDYAVWQSR" CDS_motif 23937..24026 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg18_42_0014" /evalue="2.80E-15" /label="C5_LCL_267-296" /locus_tag="ctg18_42" /protein_end="1342" /protein_start="1312" /score="48.6" /tool="antismash" /translation="DIIVGTPSAGRNHSDTEGIIGMFVNTLAIR" CDS_motif 24075..24194 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg18_42_0015" /evalue="1.10E-20" /label="C67_LCL_14fromHMM" /locus_tag="ctg18_42" /protein_end="1398" /protein_start="1358" /score="66.1" /tool="antismash" /translation="RKRVLDAFSHQDYPFEWLVEDLNIPRDVSRHPLFDTMFSL" aSDomain 24531..25724 /aSDomain="AMP-binding" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg18_42_AMP-binding.2" /evalue="1.70E-109" /label="ctg18_42_AMP-binding.2" /locus_tag="ctg18_42" /protein_end="1908" /protein_start="1510" /score="358.0" /specificity="substrate consensus: Leu" /tool="antismash" /translation="FEEQAANTPDHTALQYEGESLTYRELNERANRLARGILSLGAGEG RTAAVLCERSMDMIVSILAVLKSGSAYVPIDPEHPIQRMQHFFRDSGAKVLLTQRKLKA LAEEAEFKGVIVLADEEESYHADARNLALPLDSAAMANLTYTSGTTGTPKGNIVTHANI LRTVKETNYLSITEQDTILGLSNYVFDAFMFDMFGSLLNGAKLVLIPKETVLDMARLSR VIERENISILMITTALFHLLVDLNPACLSTLRKIMFGGERASVEHVRKALQTVGKGKLL HMYGPSESTVFATYHPVDELEEHTLSVPIGKPVSNTEVYILDRTGHVQPAGIAGELCVS GEGLVKGYYNRPELTEEKFVPHPFTSGERMYKTGDLARWLPNGDIEFIGRIDHQVKIR" CDS_motif 24717..24758 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg18_42_0016" /evalue="2.20E-04" /label="NRPS-A_a2" /locus_tag="ctg18_42" /protein_end="1586" /protein_start="1572" /score="14.6" /tool="antismash" /translation="LAVLKSGSAYVPID" CDS_motif 24957..25010 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg18_42_0017" /evalue="6.40E-06" /label="NRPS-A_a3" /locus_tag="ctg18_42" /protein_end="1670" /protein_start="1652" /score="18.8" /tool="antismash" /translation="LTYTSGTTGTPKGNIVTH" CDS_motif 25380..25403 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg18_42_0018" /evalue="8.00E-01" /label="NRPS-A_a5" /locus_tag="ctg18_42" /protein_end="1801" /protein_start="1793" /score="3.4" /tool="antismash" /translation="YGPSESTV" CDS_motif 25518..25607 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg18_42_0019" /evalue="2.10E-13" /label="NRPS-A_a6" /locus_tag="ctg18_42" /protein_end="1869" /protein_start="1839" /score="42.4" /tool="antismash" /translation="PAGIAGELCVSGEGLVKGYYNRPELTEEKF" CDS_motif 25689..25754 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg18_42_0020" /evalue="3.90E-12" /label="NRPS-A_a8" /locus_tag="ctg18_42" /protein_end="1918" /protein_start="1896" /score="38.0" /tool="antismash" /translation="FIGRIDHQVKIRGQRIELGEIE" aSDomain 26046..26252 /aSDomain="PCP" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg18_42_PCP.2" /evalue="5.30E-30" /label="ctg18_42_PCP.2" /locus_tag="ctg18_42" /protein_end="2084" /protein_start="2015" /score="95.3" /tool="antismash" /translation="EQKVADIWAQVLQAEQVGAYDHFFDIGGHSLAGMKMLALVHQELG VELSLKDLFQSPTVEGLAQVIASA" aSDomain 26295..27152 /aSDomain="Condensation" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg18_42_Condensation_LCL.2" /domain_subtypes="Condensation_LCL" /evalue="9.40E-109" /label="ctg18_42_Condensation_LCL.2" /locus_tag="ctg18_42" /protein_end="2384" /protein_start="2098" /score="354.8" /tool="antismash" /translation="DTYPVSSPQKRMYVLQQLEDAQTSYNMPAVLRLTGELDVERLNSV MQQLMQRHEALRTTFEIKDGETVQRIWEEAECEIAYFEAPEEETERIVSEFIKPFKIDQ LPLFRIGLIKHSDTEHVLLFDMHHIISDGASVGVLIEELSKLYDGETLEPLRIQYKDYA VWQQQFIQSELYKKQEEHWLEELDGELPVLTLPTDYSRPAVQTFEGDRIAFSLEAGKAD ALRRFAKETDSTLYMVLLASYSAFLSKLSGQDDIIVGSPVAGRSQADVSRVIGMFVNTL ALRTY" CDS_motif 26361..26474 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg18_42_0021" /evalue="3.30E-18" /label="C2_LCL_024-062" /locus_tag="ctg18_42" /protein_end="2158" /protein_start="2120" /score="58.1" /tool="antismash" /translation="TSYNMPAVLRLTGELDVERLNSVMQQLMQRHEALRTTF" CDS_motif 26670..26735 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg18_42_0022" /evalue="6.60E-10" /label="C3_LCL_132-143" /locus_tag="ctg18_42" /protein_end="2245" /protein_start="2223" /score="31.5" /tool="antismash" /translation="MHHIISDGASVGVLIEELSKLY" CDS_motif 26766..26798 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg18_42_0023" /evalue="2.90E-04" /label="C4_LCL_164-176" /locus_tag="ctg18_42" /protein_end="2266" /protein_start="2255" /score="13.5" /tool="antismash" /translation="QYKDYAVWQQQ" CDS_motif 27057..27146 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg18_42_0024" /evalue="3.80E-14" /label="C5_LCL_267-296" /locus_tag="ctg18_42" /protein_end="2382" /protein_start="2352" /score="45.0" /tool="antismash" /translation="DIIVGSPVAGRSQADVSRVIGMFVNTLALR" CDS_motif 27195..27314 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg18_42_0025" /evalue="7.50E-11" /label="C67_LCL_14fromHMM" /locus_tag="ctg18_42" /protein_end="2438" /protein_start="2398" /score="34.3" /tool="antismash" /translation="KETALSAFDAQDYPLEDLIGNVLVQRDTSRNPLFDAVFSM" ORIGIN 1 tgcttccccg cggcgattct atttttacca gcacacggtc ctcgatattg taggttgctg 61 ctgtttgcgg atggatttcg ataaacgatt caaaatgtct cgcggtaagg gcggcgcttt 121 ttcttgtttg gacgcctgtt aagtagtgag acatgactct gcctgttgtt aaataaagcg 181 gataatcggc tgtcggcttc tcttttggaa caggtggctc gtttggaatc acacttaatg 241 ccgctttttg atccggatga gcaaatgatt ctgtaaacaa gcgtccaatt ccgggatgat 301 caggttccgg acacggccaa tgaatgccgc cttcacgtct gagcctgccg tatgagatgc 361 ctgaataatc ggcaatcccg cctcggctcg cttctctcaa ttcatcaaaa atatcctccg 421 ctgacgtata agaaaagtag cggcccttgc cgagagcgga tgcgagatca caaatgatct 481 gccaatcatg ctttgcttcg ccgggacatg gccggcttgt ttctcttaat gtcacgcgtc 541 cttctacatt tgtcatggtg ccttcatctt ctaagtaaga ggaggcgggt aaaatcacat 601 ctgcgtattt cgcagtctca gaaataaaca aatcgattgc aacaaagaat gtcagtttac 661 gtaaagcctt tttcacaaga ttcgcatttg ggctggagac agcgggattg gagcacatga 721 ggaacaatcc tttgatgtcg ccgtcattga ttttttccat catttcatag gctgagacac 781 cttttcgcgg cagatcatcc tgatggattc cccacacttt cgcaacatgt gcccggtgtt 841 gttcgttttc aatagatcga tagcccggaa gctgatcggc tttttggcca tgctctcttg 901 caccttgccc gttgccttgt ccggtgatcg ccccgtaacc tgagtaaggt gtaccgattt 961 ttcctgtgat cagcaccatg tttaagaagc ctttcacagc cgctgttcca tcggtttgct 1021 gttcaatccc gcgggctgta aacagcatgc cggacgtttc cttggcaaac tttacagccg 1081 cttttcttat atccgccagg gggacactcg tctgttcggc gatgtcattc aggtccaacg 1141 agtcagtatg ctgcttcagc tcttcgaatc catttgttcg tgattgaatg aaatcctcgt 1201 ttataagctg ttcgtcaatg atgattttga cgagaccgtt ggcaagggcg gcgtctgtgc 1261 cgggtttgat tttcaaatga agatcggcga tttttgttgt cgctgtttca cgcggatcaa 1321 tggcaatgat gtaagctccg ttttctttcg ctttttcaaa atatggcata atcgtaggct 1381 ggcactccgc gatattggtg ccggccagaa tgatcacacg ggtgtgggga atgtctgata 1441 agggattcgt taagcctctg tccgcgccga atgtttggtt ggctgcggtt gctgcggcgg 1501 acatacaaag cctcccgttg tagtcgatgt attttgtctg taagcccacc cgtgcgaatt 1561 tccctaacaa atacgcctct tcatttgtaa tcgaggcgct tccgtatacc gccatagcgt 1621 catggccgtg ttctacttgt atcattgtca cttggtcttt aatgtaattc agtgcttctt 1681 cccaggaaac aggcataaac tcgccgtttt tcttcagcag cggccgggtg atgcgggagg 1741 agttcagggc atgctggtgg gcgttcatgc ccttcatgca tagccgaccc tgtgttgtag 1801 gattatcaat cccaatcgca gtgtactttt tgcgcgtgac gatggtttgt tccacgagct 1861 gcattttgca ctgcatgctg caaaacgggc attgagtgtc atatgttttt tctgattgga 1921 cgtcttgctg tttatcacgg aaatatctaa gcagtcgttc agtcaaaatg cctcatcctt 1981 tcttatatgc acccgtctct acagtcgggt tttgaatcag tgacagatct gtttggaggc 2041 tttccagcag ctgtgccctt aggtcttctt cgaatagcac ttctctgata tgaacgatcc 2101 cgagacggtc tatccactga tgaacacctt ctaagtaatg agccgtttcc cgataatact 2161 ggatcagtcc tttgatcatg ccggcagtgc tgtcttcgtt ctcagtcacg caaaacaaag 2221 ctcctgaacg ggcatgagtt ccccggacgc cgccgatgtg aatgtcccag ccagcttgtc 2281 tccgaattgc gccgacatct tgcagggcgg catcggtgca gtctgtttca catgataagc 2341 tgatagaaat gggagcgggt aagggaagca tctcaagttg tctttcgatt tgggctgcca 2401 gctgctgaat tgatcgattt tgcccgcatg tacatgcttt gatgctttgc agcgcgtgtc 2461 ggtgttcatt agtgtaaacg ggcatcttca ggtctttttt tatgttcggg agatccgcag 2521 gcttgatccc ggaaagcttc agcctttggc cgtgagtgat ggatacgtcg ggaatgctgt 2581 atgcctcaat gatgttggcg atggttctta gctgctccgc gtttgtccgc ccgccgtaca 2641 tttgcgggat caggatgcat gtctcttcag tggctggctc aggctggaca aacccagggt 2701 acagcatttc cagatagtat tgaatcgcag gaacacaagt actgcatccg ttttttgttt 2761 tccagtcaag ctggttcatc acttctgccg gattagtgaa tggcctgcgc tgaagctcag 2821 cgatgatgtc gtcttctgta aaatcagtac agctgcaaaa cgaaggtgtg ccggcgggct 2881 tcgtatattc gctgttggtc atgtgcctca aaaggtcttc aacgagcggt ttgcatcctc 2941 cgcaggaccc agtggctttg gtgcagtgct tgacttcctc aacagttgtt aagctattcg 3001 tgtgcaccgc ttcttcaatc gcgcctttcg tcactgtgtt gcattggcaa atcgtttcac 3061 tggaaggcat ggattcaaat aaagggccgc ttgtctccgg ttcgatgatc tgctttttga 3121 caatggagat gtctcgttgt ttaaggaggc tgtcgagaag ccgctgcttg tcacgggtgt 3181 ctccgaataa aataacgccg gccagttttt catctacaaa aagcgctttt ttataaacgc 3241 ctgcttgttc gtcgtagatt ttgatgctcg tcgtgcgttc atcctcttgg atctttcctg 3301 ctgaccacac atcgattcca gctattttta acgccgctga tggtgctgag ccttgatatt 3361 cctcacatgg aacgccgcaa atatgactgg cgagcgcttt tccctgctca taaagcggag 3421 ccaccaatcc gtacaccgtt ccgttatgct cagcgcattc accaacggcg tagatattcg 3481 gttcgcttgt ctgcatgaag tcattcacga tgatcccgcg gttcactttg attccagcgg 3541 atacagccaa ttcaatattc ggtttgacgc cggccgccat cacaatcaag tctgctttta 3601 atgaagagcc atctttaaaa tggattcggt ctgccttcgt ggcgccggaa atggagacgg 3661 tgtctttctc caaaagaaag gttaggcctt tttgttccag ctctgtttgc agcagccgcg 3721 ccgctgtttg atcgagctgt ttttgcataa tgccggcgga gtggtgaatg acgctgacat 3781 ccataccgag atgctgtaaa cctactgcag cttccagtcc taataagccg gctccgatta 3841 ccgcagcctt ttgaaagtgc tgggccatgt tcatcagcgc ttggcagtct tctattgtcc 3901 gaaatccata gacacctttt ttgtctgccc cggggatagg gagaatatga ggggaggagc 3961 ctgttgccac tattaatttg tcatacgaca gagtgcgttt ccgatctgtg atgacctgct 4021 gctgatctgt atcaatctga ataaccgttt cgcctgtgta aagcgtgatc ccgtgcttgt 4081 cgtaccaatc cttgctgttc agtgtaatat catcgagtga cgcttcaccc tgcaatacag 4141 aggataagag aatgcgattg taattgggat gcggctcgct tccgaaaatg acaatctcaa 4201 acatgtggcg attcagcttt aatacttctt caatacagcg gattccggcc atgccgtttc 4261 ccgctaacac taatctttgt ttcttcatgt atcagacctc ctttggcgaa gctcgtaagt 4321 tttctcctat taaaaattat gtcacaatgc attgttaacg cattaaacgt gtcacaaaaa 4381 cttacacatg tcttttccag aaaataatgg tcctatatcc ttgattcaga aaatgtaaaa 4441 taatgagggt ctagaaaggg gaatcttatg aagctgtcgg aactgaaaac tagcggtcat 4501 ccactcactt tgctctgttc ctttttatac tttgatgtca gttttatgat atgggttatg 4561 cttggggcgc tgggtgttta tatttctcag gattttggcc tgtctccttt tgagaaaggg 4621 cttgtcgtag ctgtgccgat tttatctgga tctgtgtttc gtatcattct tggtatttta 4681 acggacagaa tcggaccgaa aaaaacggca gtgatcggga tgctggtgac gatgattccg 4741 ctgctttggg ggacattcgg cggccgttcc ctgactgagc tgtatgccat cgggattctg 4801 cttggcgtgg cgggagcaag ctttgctgta gcgctgccta tggccagccg atggtatccg 4861 cctcatttgc aggggcttgc gatggggatt gccggagcgg ggaacagcgg cacgttgttt 4921 gcaaccctgt ttggccctcg tctggcggag cagttcggct ggcacattgt catgggaatt 4981 gcgctaattc cattattgat cgtctttatt ctttttgtat ccatggcaaa ggattcccct 5041 gcacagccgt ctccccagcc gctcaaaagc tatctgcatg tgttcgggca aaaggaaaca 5101 tggtttttct gcctgctgta cagcgtcaca tttggcggat ttgtcgggct ctcaagcttt 5161 ttatctattt tctttgttga tcaataccag ctgtcaaaaa ttcacgcggg cgacttcgtt 5221 acattatgtg tggcggcggg gagctttttc cggcctgtcg ggggcttgat ttcggatcgt 5281 gtcggcggca cgaaagttct ttctgtactg tttgtcatcg tggcactgtg tatggccgga 5341 gtcagcagcc tgccatctct ttcaatggtt attgttctat tgtttgtcgg aatgatgggg 5401 ctcggaatgg gaaacggcgc agtattccag ctcgtgccgc agcgttttcg caaagaaatt 5461 ggcatggtga cgggaatcgt cggtgcggcc ggaggaatcg gagggttttt cctgccgaac 5521 atcttaggat ctctcaaaca gatgacaggc acatatgcta tcggttttat cacgttttcc 5581 tgtatcgcgc tgctggcgtt tgcacttgtg cttgccgcag gctattactg gcggaaaagc 5641 tggagcgcgg aaagcagccc ggcggatgtt tagggttttg acggacacgc gtttgtgcgt 5701 gtctttttta ttttctcttg attttcaaca gtgaaccgat caaaataaat agtaattatt 5761 acgatttgtt agtgagagga gttttctgaa tgaatcaaca tacgctgctt ccgaaaaaaa 5821 cggagcgtct tcaatacttt ggatcggtca gtccgatcaa aggcgagaaa ccagtggaaa 5881 aagagaaaat gaaggacctg caaaatatca ggaaggatta tttttttgac attcagcatg 5941 taggtgtcgc taatgtgtcc catccagtca caatcacttc tgccatgatg cctgccgagc 6001 aaacaacggc tgcgaacttt acaatgactt gtaatttgcc gagaaatcag aaggggatta 6061 acatgagccg gttaacagag ctgctgcaag tctatcatca aaatggctgg attctctcat 6121 tttcctctct tcagcaattc acgaaagagc ttgcagaaaa catggacaca tcacctgcct 6181 cagttgaagt gaggtttccg tggtttttcg aacggaaaag tccgaagctt gagaaagcgg 6241 gtttgatgca tgctgatata ttcatgtctg tcacctatcg caaagatcag ccgtttaaac 6301 agcgtgccgg catctcagca aaagtaacga ctctgtgccc ttgctccaag gaaatcagcg 6361 aatacagtgc ccataatcag aggggaacgg tcagcatttg ggcggatatt cacccggctg 6421 catcgctgct gatttgtttg agcttgaatg ggtgtcggcc tttgagattg aatgccgcaa 6481 tgaagaatcg atccatctcc acgatgccta tgcgaagctg tgtttttcga aggaagtgga 6541 taaaatatga aactctcatt attcattatt gcagttctta tgccagcctg cctgctgtca 6601 acctgctccg aacatgcaga agaacacgca agtatcaata caaagaaaac ggtcgaaaac 6661 ataacggacg ttcgaaaaac agcaaaaata agcattgatt ggacgaagcc ttcgggcgga 6721 gaatacccgg atattaaaca gaagcatgtc tggattgatg tgaatgtgaa ggagcagaag 6781 gcttacatca aggaaggaag caacaccatc tatacaatga tgatctcttc tggtcttgat 6841 caaacaaaag atgatgctac gccaaagggc accttttatg tagagcctga acggggagaa 6901 tggtttttct ccgaaggata ccaggaaggc gcagaatact gggtatcatg gaaaaaccac 6961 ggcgaatttc tatttcatag tgtgccaatg acaaaggatc aaaaagtcat caaaacggaa 7021 gcagaaaaac taggaacgaa agcatctcac ggttgtatca ggctgaccat tccagatgca 7081 aaatggatat atgaaaatat ccctgaacat acaaaagtgg tgatcagctg aattgaaaac 7141 cgttgacaaa aaggaaaaaa gaccatacaa tttaaatcgt aataattacg ttttgtggta 7201 aatggcttat cattggctgt atctgtgaaa agcggaaagg ctaaggatct tgctgtcatt 7261 gatccccatg aagcgtcttg ttgaaaactt gaaacgaaac ccaagctact ttctgatgag 7321 atgtttgcgc tttccatcgg ttcagcaacg caagtggagc aattgcttta tgcaagctgc 7381 ggttttccga atgtcggcaa gggcagggat ttgcgatggg gaaaaggatt aaacgcggtt 7441 ggagccttta ctgatttaga aatcgggcag cagcgagaaa tgagcgcgaa aagctgctct 7501 acaccattgt acatatggcg aagtatacaa tttaaatcgt aatcattcta ttttaatgga 7561 ggcactatta tgaaaaagat tccggttacc gtactgagcg gatatctagg tgcgggaaaa 7621 acaacattgc tgaacagcat tctgcaaaat cgcgaaggct tgaaaatagc ggttatcgta 7681 aacgatatga gcgaggtgaa cattgacgcg ggcttggtta agcaggaagg gggcctttcc 7741 agaacagatg aaaagcttgt ggaaatgtca aacggctgca tttgctgcac gcttcgcgaa 7801 gacttattaa ttgaagttga gaagctggca aaagacggac ggtttgatta tatcgtcatc 7861 gaatcgacag gaatcagcga accgatcccg gtggcccaga ctttctctta tatcgatgaa 7921 gagatgggaa tcgatcttac aaaattctgt cagctggata cgatggtgac agtggttgat 7981 gccaaccgtt tttggcatga ttatcagtca ggcgaaagcc ttctggaacg caaagaagca 8041 ttgggggaag aggatgaaag agaaatcgcc gacctcttga tcgatcaaat tgagttttgc 8101 gatgtactga tcttaaataa atgtgatttg gtcagcgagc aagagctcga acagcttgaa 8161 aacgttcttc gtaaactgca gccaagagcc aagttcattc gctgtcaaag gaaatgtaaa 8221 accgcaggag attttgcata cagggttatt taacttcgag gaagcgagcg gatcggccgg 8281 ctggattcaa gagctgacgg caggccatgc ggaacacacc ccggaaacag aagaatacgg 8341 tatctcttca tttgtatata agagacgttt gccgtttcat tctacacggt tttatcaatg 8401 gatagatcaa atgccaaaga acgtggttcg tgccaaagga atcgtctggt gcgcatctca 8461 taacaacctc gctttgctga tgtcgcaagc aggtccgtcg gttacgattg agcctgtatc 8521 ttattgggtg gcggcgctgc cgaagcttga gcaggagcaa gtcaaacagc aggagccgga 8581 aatcctggag gagtgggacc cggagttcgg cgaccgccta acgcagctag tttttatcgg 8641 aactgacctg gatgaagaaa cgatcacgaa agagcttgat caatgcctgt tgactgagta 8701 tgaatttgat tccgactggt cgctgtttga ggacccgttt aaatggaagc tgaatcaata 8761 gaaaaaaagc cgtcccctgg agaacggctt tttttaatga aacgtttgtt taaacataat 8821 gagcgtattt tttctcaagg atattctgaa agaccgcggc aatggagcag atggcccaat 8881 aaatgagagc ggtcagaata tacatggtca tataatcaaa ctctctgccc ccgatgattt 8941 tcgcatgctg gagcaattcc ggcactgtaa tcatcgcagc gagagaggac gccttgatta 9001 agtcgagcaa tacattggca agcggaggca gcgcaatatg tatcgattgc ggcaaaatga 9061 tgcccctcat cgtctgccaa taggaaagac ccagcgagga tgcggcttcc cactgtcctt 9121 tttcgacgga tgaaatggct gaacggttaa tttccgcaat gtaggcggcg ctgttaaggc 9181 taaaaccgat taaagcagcc gtgacagcgg aaaattgaat gctgatataa ggaaacccga 9241 aataaaggat aaacaaaatc actaaaatcg gaacgccccg cataaatgag atatagagct 9301 tcgccggcca tcttaacaaa gcaagcttag acattctagc gagtgatatg aacaggccga 9361 tcacagttcc tgcaaacatg cttacaaaag agatgagcag tgtataccca atgcctttta 9421 tgacataagg gaacgattca atgaccagct tcgtgttgaa aatatattcc cattgaatgc 9481 tattgatcat ggcgtccgat tacaaatcaa cgtcctgaac gtcggcatca attttttttg 9541 atacatctgc tttattgaag aattgtttcg acagtttagt caaagagcca tccttgctca 9601 tctctttcaa tgcttcgttc atctttttct gaagtgcctc attgcttttt ttcatgacaa 9661 gggcctgttt gttcggcatg tacttgatgt caggatgaat tgtaatgttg agatccggga 9721 atgccgcgag cgcaagtgtc tgcaggtaat agtcgtttaa aatgacgtca gtgcgtccgt 9781 tggcaacatc ttttaaatat tgctcattcg tcgcattatc ataaatcact tctttggcgc 9841 cgtattttct cgcgacctcc atgtagacgg ttgtagccgc gccagccgct ttcttccctt 9901 ttaaatcctt aagcgtttta atccctgata aatcgtcttt tcggacaatt gccgtaccgt 9961 atgaatattt atatggagta gaaaatgcga acttcttctc gcggtccttc gtcacatcga 10021 tgtcattcgc ggctgcgtca acctgtccgc tgttcaccgc tgtcagcatc ccgtcaatgc 10081 ccatctcctt gaactcaacc ttcagtccca ggcgttttgc cgcttcacga acaacttcaa 10141 cctcgtagcc cgtcagctta tcggagcctg agtcagtatc gtgataagaa gtggggtaga 10201 gcgtacctga tgtagcgact acgattttcc ctttgtcctt gatttgctcc cagcctgtat 10261 ccttggaatc ggcttcattt ttgccggaac aggctgccaa tataagaaag aaagccattg 10321 tgaaactgaa tataacggct ttggattgct tgaatgattt cacctatatt tcccccaatc 10381 tgttaatcaa ctaaaaagat agcattgaac ataaggggtt gcaatatgtt gatcgcgttt 10441 tcaaaaagtt cgaattgtgt atacaaaagg catagtaggt gtttaatagc ggctatgaag 10501 ggaattggtg atgaacaaag gagttgtcca aggatgaatg cccgacgtac caaggaaaca 10561 catgtggacg tgaaggatgc agcagatccg ttattcctct atgccaatac cgtaagaaat 10621 ggtcaagaag catgaaaccg atcttcagaa taaatttaag tcttgctgat gcccctaagg 10681 catatgatat attcgatgag aaagaaaacg gaaacattta aaccataatg ggggagtcaa 10741 atgaatattt acaaaccagc cggattttgg atcagacttg gagctgcatt gttagactac 10801 attatagtct ccgtgccgct tttgctgatc tattggctga ttacaggaaa agacccaaac 10861 gacagcatgt tcatcagttt ggttgttctg ctgtattcta ttttgctgcc ggtgttttgg 10921 cacggttatc ttatcggaaa aaggatctgc ggaatcagaa tcgtaaaaaa agaaggatca 10981 caagtcagcc tgttaacaat gtttttacgg gttattgtag ccggcctggt ttactttata 11041 accttcggac tcggcttgat cgccagcctg attctgattg ccgtacgaga agacaaacgg 11101 accctgcatg atttaatcgc gggaacatat gtcacttatg cgacaccagg tgaagaagaa 11161 cttaatactg acgaagagat tagaaagagc gaataatggt tcgctctttt tatttttatg 11221 cataaaaaat acaaggcagc aaaccatatg aaaaatagga ttggaggaat aaactggatg 11281 aaacgaataa ccattaacat cataacaatg ttcattgcaa cgactgtcat ttctctgacc 11341 ggtacagctg aggccgctga aaaacagcag cagcctcccg caaatgttac actgacagat 11401 cagcaaaaga aagaggttga acaactggaa gcagagattc ttaaaaagcg caaagacgta 11461 atctcaaagt atgtacaata cggtgtcctg cctaaagaaa gaggagaaca cattaaaaat 11521 cacttggaca aacactttga aatgatgaaa caaaacggct ttgttccaaa gcaccatcct 11581 catccgcata aatttgaaaa aagacattaa gatggaaagc atccaatggg aattgggtgc 11641 ttttttattg ttaaaagtta ctgaatgaat tttccgaaaa aatatatcgc ttttattgat 11701 tatatcttat aataagatat aaatcgggtg tataatgatg gaaatggatt taatctctaa 11761 acttaatcag cagtggacag atatttatta tttattacat tatcaacata aagataatat 11821 ttctcaccag gcaatacgga ttatgcagca tattgaaaag caaggtgagg tgacaatagg 11881 agctttggct gaatacttgt ctgtctctca caatacagcg tcagagcata ctaaacgttt 11941 gattcaaaag ggatttatag ctaaacggcg aagtcaacag gatgaacgaa aagttttagt 12001 tttcttaaca caagaaggaa gatctgttct tgaacagcat acacagctag ataaagagaa 12061 attaaaagaa ataattgaac gaatgagcac atcagaaaag caattacttg aacaggcatt 12121 tgaactttta agtagggaag ctaaacaatg gcagttttaa gtaaagtaat catctctgcg 12181 ttgattatcg gttttgttac tgaaatatca aaaagacatc cgacctatgg cggcatcatt 12241 gctgctttgc ccttggtcag tttattaagc cttttttgga tgcaaataca aagtcaattt 12301 gcatctggtg tgcttacagg aatcccagct acagtttgtt tactagctat tttggctttt 12361 ttgctgaaaa ttcatgtgcc gttttggttt gcattatgtg ttggaatact aggatgggct 12421 atgtttttat ggatgcagaa gatatttctc aatatattat ttaactgagt atagaaagga 12481 gatgctatgt ttttaaaaaa ggttactctt cttcgagata agattttgga ctttgacaga 12541 tttcctttta ctatcccggc tataagtcaa ttaaatgaca tcttatttac tagccaagtg 12601 actttttttg tgggggaaaa tggatctgga aaatctactt tgcttgaagc gatagcagat 12661 aagtgtgaat tcaatacagc gggcggaagc cgaaataatg tctatgaatt acgggagtca 12721 gattcccatt taggagatta tatacgttta tcttggcttc caaaggtaac aaatggcttc 12781 ttcttaaggg ctgaatcgtt ttatcatctt tctcttcatc tggatgagat ggaactagat 12841 gctcctcagc cataccgttc ctatggaggg aggccgctac acaatcaatc acatggagag 12901 tcctttatgt ctctattccg tcatcgtttt aaagagaaag cgatttacct tttagatgag 12961 ccagaagcag cactttctcc agctagacaa ttagcttttt tgagagttat acatgatttg 13021 gtgaagggcg gaattggtga agggcggaaa tgtacagatg atcattgcga ctcactcccc 13081 aatcctactg ggctatccca atgctaatat tttaagcttt gatggtggaa gaatacatca 13141 tattgaatat gagaatacag agcatgttca attaacacga tattttcttg gacaaagaga 13201 aaaaatatta gcggagctgt tccgtgacta acatcgagtt gatatgaaac gcgtttcata 13261 gcctatgata ggtttatcaa ataattcagg agtgataaac actatgatcc accagcatcc 13321 agaatctttt ccgaaacatt ttttgtgggg ctctgcttct gcagcgtacc agattgaagg 13381 cgcttggatt gaagatggca aaggcccttc tgtttggtat gtgtttacga aaataccggg 13441 caaaacgttt aaaggaacca atggcgacat tgccattatc accgatttaa agaagatgtc 13501 gctctgatgg ctgagatggg gttaaaagca tatcgatttt ccgtcagctg gccacgggtt 13561 tttccaaaag gaaaaggaga gatcaatgaa gcaggtctag cgttttacga tagtctgatt 13621 gatgaattga tttctcatca catcgagccg gttctgactt tatatcactg ggatttgcct 13681 caagcgctta tggacgaata cggcgggttt gaatccagaa acatcataga ggattttaat 13741 cactactgta ttactcttta taaacgtttt ggagacaggg tgaaatattg ggttacgtta 13801 aacgaacaga actacaattt taatcacgga tttattacag ccatgcatcc gcctggagtg 13861 aaagacagaa aacgatttta cgaagcaaac catattgctt ttctggctaa tgcaaaagcc 13921 atcgaatcat ttagagaata tgtgcctgaa ggcaaaatag gtcctagctt tgcttattct 13981 ccggcttacc ctttatcaag ccatccagag gatatactgg catttgaaaa cgccgaagaa 14041 tttacgaaca attggtggct tgacatgtat tgctggggaa cctacccgca aattccattc 14101 cgctacttgg aaaaacaggg atgggcgccg acaattgaag caggagatat ggacctgctc 14161 gccaaaggga aacctgattt tgtaggtgtc aattattatc agacgatcac ctatgaacga 14221 aatccgcttg atggtgtgtc agaagggaaa atgaatacga caggccaaaa gggaaccaat 14281 caggagacgg ggatacccgg agtgttcaaa acgaaaaaaa atccgcatct gacaacaagc 14341 aactgggatt ggacaattga cccaattggg ctgcgtatcg gtcttcgccg aattacaagc 14401 cgctatcagc ttccagtgtt tataaacaga gaacggtttg ggtgaatttg ataaagttga 14461 ggacggcact gtacaggatg attatcgaat tgattattta cgttcgcatc ttgagcaatg 14521 cagacaagcc atcagtgacg gtgttgattt aatcggctat tgcagctggt cgtttactga 14581 tctgttaagc tggctgaacg gctaccaaaa aagatacgga tttgtatatg tcaatcgtga 14641 tgaagaaagc acatacgatt taaaacgctt gaagaaaaaa agcttttatt ggtatcaaga 14701 tgtcatcaag acgaacggag aaagtttata aagagtccct gagagttatt ctctcagggg 14761 tttttcatta cacagaaaca gcatcaataa tataagtgtc ggcgtgcaaa tctgacattt 14821 cagccggcac agtccagcat gtcaattgat agtctccttt aggcagatca aaggacagtc 14881 tcttagacat aatgctttca atatgaattc cgttttctgt gacatgaaaa ggaacagtca 14941 cttttttttc gtaggagttt actgtttctg aactgttcag gcgcaaaaga ataaaggcct 15001 ttgtatttcg ctgtgcctca aatgaaatgg ctccgtctgc cgcagtatat cctttttcaa 15061 tcgcttcgtc agtccaatcc attataggag gtgtagaatc cttttgaaat acagtaaatt 15121 gatgatatga aatcgaaagt tcttgcggct tccatgattt gatcaatgtg ctgttcctcc 15181 tctatgtact gtttactgaa ttgtgaataa aacctttgtg ccgtctgggt aatcggtaag 15241 ctgatgcccg acccaagagc ctgctccgcg gttgtcagcg ggagaaatgt attctacaga 15301 agctccctca ccgccttctt tgcacatggc cattggccat tcatctctgt catacccctt 15361 tttggaaggt acgtccttta atgattgctc gcggcgttct tcagctccgt ctctgtcaat 15421 agtgcacacc tctgagtgcc cctcatttat cgcatcctta atatgcttgg cagtttcggg 15481 ataccggtca gatgggaagg cgattgtttc atcatattct ttcgtttgag acgttttttg 15541 atcagctgag aaaaagtctc cttttatcag gccgacagct gcagctgcta tgatgacgat 15601 gacgagaagt atcgttttta tgatgtccgt cgtgatgttc acctcccgct tttaaaactg 15661 acacaagagt aatccagaaa gcatttggtg taaaggttta aattttatgt tttacgctca 15721 gtttattgca gaaatcgtaa ttttagcaga tcgaaatatt tgttttcagc aaaatacgat 15781 tgccaattta caataatgat agtaagtcat cagccgtttt cggcttgatt aatcatttta 15841 aattggctta tgataccggt aagctcctca gctaattgag aaagtgtttc agaagctgcg 15901 gtaatctcct ccattgcagc aaattgctcc tctgttaatg cagctgcttg ccgggtattt 15961 ttagtagatt ctttaatgtc ggccgtattg gctgcaaagg aatgatttat atgatgtgca 16021 ctggctgaaa tgtttgttac agatgctgat aaatcactaa tctcggcact gatttcacct 16081 gttgcagctg caatttcctt aaatgcatct ctggtgcgct ggatcatggt gactccttct 16141 gcagcttctg ttttcacatg ctcaacagat cttgcagacc ggttcatatc cttttgtatt 16201 tctatgatca gttttgaaat ctgccccgcg gactgttgag actcttctgc taatttccgt 16261 acttcatcag caacaacagc aaagcctttt ccttgttcac cggctctggc agcttcaata 16321 gctgcattca gcgcaagcag gtttgtctga tcggcaattt gggtgatgac cgataaaatt 16381 tgctcaattt gtttagagcg gccgtctaac tggtgtatga tttctccgct tttctgaatt 16441 gactggtgaa tcgcatccat ttgcgcctgt acatttgcaa tttccttttg tccaatgtct 16501 gcttttgatt gagcgagctg ccctttgtca gcgatagcgg cagtatttgc agaaatatcc 16561 cggatgtctg ctgaagcttg ttttaatgag ctttcactat tttcaattcg gatgatctga 16621 tcttgggctc catttgcaat ctactgtaca gcttctgtga ttttttctga agcttgattt 16681 gtttcctctg ctccggctga gagctgctga gaggctgacg caagctgaag ggctgattgt 16741 tgtacggttt gtatggtatc gttcagcttc attctcatct tattataata gacgcttagt 16801 tctgatagct cgtcaccggt tttgtctgac acctctattg tcatatctcc gtttccggca 16861 ctttcaaagg cgctttttaa agcgttcagg cgcttgttga tttttctggt gaaaaccaag 16921 acaaggatga ctgatagcat aatgacgata acaagaacga tagcgaattg agtgaaaagt 16981 gattgtgtaa gtgatgctaa aatactttga ttagctccgg tatacagcat gccgatgatg 17041 ctcccgtttt gatcttttaa cggcatgtat gcagtctgat aagaagaacc tgctacatct 17101 gcttgtccgt aaaaacactt tcctttcttt aaaacagcgg caataacttc agaagaagcc 17161 tgagtgccga cagctctttc gccatttttc atgacattgg ttgcaacacg agtatcgcct 17221 tggaaaatgg taatggtatc acctgttttt tcaccaagca gatcaacaag ctcttcattt 17281 ccattgattt gtgtttgccc tttatagagc ttattgtttt tcacctgcca gtcgcctgat 17341 atgacatcat caatataagt gctgcttaaa gcgagatcac ctttcgcttt ttcagttgcc 17401 atttgtttca tgttttctgt aatttcctta agcatcacag tgccaactga tgccgaaaac 17461 aaaagaatca ccacgaaaac gaggcaaaga attttagttc ctagcttcat cttaaatcgt 17521 tttatcaaca taattcctcc ttttaggatt tgaggtcata ttacttatcg ggttttcggg 17581 tttaaagttt tattttagaa aaaataaaac cggcctgatc ttcaggccgg ttgtgtgatg 17641 ctattcaagg tttgcgtggt gagtgaacat agtttcagaa tcgagtcctt ttttctccat 17701 gagttttaaa atcactgcat catagaatag cagcaaagtt tgttcaaata atgatcccat 17761 tggctgaatg gttttatagc ttccgtttga cgggtcttta ggagaaccag gcattctgat 17821 gatgaggtcc gcttgttttc cgacgcttga ttccggattg atggttaaag cggcaacaat 17881 tccgtgtaag ctttttgctt ttgctgcggt atgaatcaag ctctttgtct cgcctgatcc 17941 tgagccgata ataactagat ctccttcggc gagcggcgga gtgagaatct cacctactat 18001 atgggcgttg aagcccatgt gcatcagtct catcgcgaag gattttgcca tcaggccaga 18061 ccgacccgca cccgcggtga aaatttggtg ggatgacaga atgtgatcgg caagctggtc 18121 agcctcttca ttagaaatat aagctgctga attgtgtaac tcattgagaa tttccgctac 18181 gtattcagtc gttttcatag aagttatcct tggacaatca gctgcttcat ttttgaagct 18241 gtttccgcct tatcagctgc gcttgtaatt ccgcccccaa caatgacaag gtcagggttt 18301 tgcttgatca cttctggcag tgtatcaagt ttgatgccgc ccgcgattgc ggtttttgcg 18361 ttttttacgg tatttttgat tgtcgttaat tcttcgaaag agtttttgcc ctctgcttga 18421 agatcatagc cagtgtggac gcagatgtag tcaacaccga gtgcgtcaat ttctttcgca 18481 cgggattcga tatccttcac gttaatcatg tccactaaga ttttcttctt ttgttttttg 18541 gcttcttcta ctgcgccttt aatcgttgca tcgtctgtag cccctaaaac ggtgatgatg 18601 tcagcgcctg cttccgacgc tttcataatt tcgtagcctc cggcatccat gattttcagg 18661 tctgcaagaa ccttcaattg aggaaatgct tcttttattt ctttaacggc tcttaggcct 18721 tcattgatga cgaccggtgt tccgatttca actacgtcga tgtattgttc tacctctttg 18781 acgagctcaa tggcttccgg gatgttgacg aggtctaatg caagctgtaa ttccattgtt 18841 gatccactcc ctttttcgaa ttatttttca ttctataggt tccttctttt gatgagaagt 18901 aggcactttg aagtcaacaa gttacttgga ggatactgtg aggagagaca atcagatttc 18961 tttcgcttga ttttatgagt gagtataatg aaaaaagagt ctgcaaaaaa gtaagtgatg 19021 atacgtatct aacatacaaa aaggttacta agggggggat tctattgagc cggatggacg 19081 acaaaaggtt taattgtgag aaggaattaa cgcttgcagt gattggcggt aaatggaaaa 19141 tgctcatttt atggcattta ggaaaagaag gcacaaaacg gttcaatgaa ttaaaaacat 19201 tgattcctga tattacgcag aagatcctcg tgaatcagct gagagagctt gagcaggata 19261 tgattgttca cagggaagtg tatccagttg tcccgccgaa ggttgaatat tctctgaccc 19321 cgcacggaga aagcctcatg cctattcttg aagccatgta tgagtggggg aaaggttata 19381 tggaattgat tgatatcgac aaaaatgtca tgaaagaatc gttgtaagac gctcttcgca 19441 agggtgtctt ttttttgcct ttttttcggt ttttgcgcgg tacacatagt catgtaaaga 19501 ttgtaaattg cattcagcaa taaaaaaaga ttgaacgcag cagtttggtt taaaaatttt 19561 tatttttctg taaataatgt ttagtggaaa tgattgcggc atcccgcaaa aatatccctg 19621 taaataaact ggaatctttc ggcatcccgc atgaaacttt tcacccattt ttcggtgata 19681 aaaacatttt tttcatttaa agtaaacggt agaaagataa aaaatattga aaacaatgaa 19741 taaatagcca aaattggttt cttattaggg tggggtcttg cggtctttat ccgcttatgt 19801 taaacgccgc aatgctgact gacggcagcc tgctttaata gcggccatct gttttttgat 19861 tggaagcact gctttttaag tgtagtactt tgggctattt cggctgttag ttcataagaa 19921 ttaaaagctg atatggataa gaaagagaaa atgcgttgca catgttcact gcttataaag 19981 attaggggag gtatgacaat atggaaataa ctttttatcc tttaacggat gcacaaaaac 20041 gaatttggta cacagaaaaa ttttatcctc acacgagcat ttcaaatctt gcggggattg 20101 gtaagctggt ttcagctgat gcgattgatt atgtgcttgt tgagcaggcg attcaagagt 20161 ttattcgcag aaatgacgcc atgcgccttc ggttgcggct agatgaaaac ggggagcctg 20221 tacaatatat tagcgagtat cggcctgttg atataaaaca tactgacact actgaagatc 20281 cgaatgcgat agagtttatt tcacaatgga gccgggagga aacgaaaaaa cctttgccgt 20341 tgtacgattg tgatttattc cgtttttcct tgttcaccat aaaggaaaat gaagtatggt 20401 tttacgcaaa tgttcatcac gtgatttctg atggtatctc catgaatatt ctcgggaatg 20461 cgatcatgca catttattta gaattagcca gcggctcaga ggcaaaagaa ggaatctcgc 20521 attcatttat cgatcatgtt ttatctgaac aggactatgc tcaatcgaag cggtttgaaa 20581 aggacaaggc gttttggaac aaacaatttg aatcggtgcc tgaacttgtt tccttgaaac 20641 ggaatgcatc cgcaggggga agtttagatg ctgagaggtt ctctaaagat gtgcctgaag 20701 cgcttcatca gcagattctg tcgttttgtg aggcgaataa agtcagtgtt ctttcggtat 20761 ttcaatcgtt gctcgccgcc tacttgtaca gggtcagcgg ccagaatgat gttgtgacgg 20821 gaacctttat gggcaaccgg acaaatgcga aagagaagca gatgcttggc atgtttgttt 20881 ctacggttcc gcttcggaca aacattgacg gcgggcaggc gtttttagaa tttgtcaaag 20941 accggatgaa ggatctcatg aagacactcc gccaccaaaa gtacccgtat aatctcctga 21001 tcaacgattt gcgtgaaaca aagagttctc tgaccaagct gtttactgtt tctcttgaat 21061 atcaggtgat gcagtggcaa aaagaagagg accttgcctt tttgactgag ccgattttca 21121 gcggcagcgg attaaatgat gtctcgatcc atgtgaagga tcgatgggat actgggaaac 21181 tcaccataga ttttgattac cgcactgctt tatttacaag tgaagaaatc aacatgattt 21241 gtgagcgcat gattacaatg ctggagaacg cgttaacgca tccagaacat acaattgatg 21301 aattaacgat gatttctgat gcggagaaag agaagctgct tgcgagggcc ggcggtaaat 21361 ctgtgagcta ccgtaaggac atgacgatcc cgaaactgtt ccaagaaaag gctgagcagc 21421 tttcagatca tccagcggtt gtatttgaag atcgtacatt gtcttatcga atgttacatg 21481 aacaatccgc acgcatcgcc aatgtgctaa aacagaaagg ggttggcccg gacagtcctg 21541 tcgcggtttt gattgaacgc tctgaacgga tgattacagc tatcatgggg attttaaaag 21601 ccggcggagc ctatgtgccg attgatccgg gttttcctgc tgagcgcatt caatatattt 21661 tggaggactg cggggcggac ttcatcctga ctgaatcgaa ggttgcggca cctgaagccg 21721 atgctgagct gattgactta gatcaggcaa ttgcagaagg tgcagaagaa agcctgaatg 21781 cagatgtgaa cgcacggaac cttgcctaca ttatttatac atcgggaaca accggacgcc 21841 cgaaaggcgt tatgatcgag catcgccagg ttcatcattt ggttgaatct ctgcagcaga 21901 cgatttatca aagcggcagc caacccctgc ggatggcatt gcttgcgccg ttccacttcg 21961 atgcgtcagt gcagcagatc ttcgcgtcgc ttcttttggg acaaaccctt tatatcgtac 22021 cgaagaaaac tgtgacgaac ggggccgccc ttgctgcata ttatcggaga aacagcattg 22081 aggcgacgga tggaacacct gctcatttgc aaatgctggc agcagcaggc gattttgaag 22141 gcctaaaact gaagcacatg ctgatcggag gagaaggcct gtcaactgtt gttgcggaca 22201 agctgctgaa gctgtttaaa gaagcaggca cagcgccgcg tttgaccaat gtatacgggc 22261 cgactgaaac gtgcgttgac gcgtctgttc atccggttat ccctgagaat gcagttcaat 22321 cagcgtatgt gccgatcggg aaagcgctgg ggaataaccg cttatatatt ttggatcaaa 22381 aaggccggct gcagcctgaa ggcgtggcgg gcgagcttta tatcgcggga gacggtgtgg 22441 gccgaggcta tttacatttg cctgaattaa cggaagagaa gtttttacaa gatccattcg 22501 tgccgggcga tcgcatgtac cggaccgggg acgtggtgcg ctggcttcca gatggaacaa 22561 tcgaatattt aggcagagag gatgaccagg tcaaagtccg cggataccgg attgagcttg 22621 gggaaattga agccgtgatt cagcaggcgc cagacgttgc aaaagccgtt gttttggcac 22681 gccctgacga acagggaaat cttgaggttt gcgcatatgt tgtgcagaag cctggaagcg 22741 aatttgcgcc agccggtttg agggagcatg cggccagaca gcttcctgac tatatggtgc 22801 cggcttactt tacagaagtg acagaaattc cgcttacacc aagcggcaaa gtcgaccgcc 22861 gcaagctgtt tgcactagag gtgaaggctg tcagcggcac tgcctataca gcgccgcgaa 22921 atgagactga aaaagcaatc gcagccattt ggcaggacgt gctgaacgtt gagaaggcgg 22981 ggatctttga caatttcttt gaaactggcg gacattcatt aaaagccatg acccttttaa 23041 caaagattca taaggaaaca ggcattgaga ttccgcttca atttttgttt gagcatccga 23101 cgattacggc tcttgcagag gaagctgatc acagagaaag caaagctttt gcggtgattg 23161 aacctgctga aaaacaggag cattacccgc tttcattggc acagcagcga acatatatcg 23221 tcagccagtt cgaggatgcg ggagtcggct ataacatgcc agcagcagca attctggaag 23281 ggcctttaga tattcaaaag ctggagcgcg catttcaggg attaatccga cgccacgagt 23341 cattgagaac atcatttgtt cttgaaaaca gcacgccgag acagaaaatt cacgatagcg 23401 ttgatttcaa catcgaaatg attgaaagag gcggccgctc agatgaggca attatggctt 23461 cattcgttcg gacatttgat ttggcgaaag ctccgctgtt cagaatcggt ttgctggggc 23521 ttgaagagaa ccgtcatatg ctgctgtttg acatgcacca tttgatttct gacggtgtat 23581 ccattggcat tatgctggag gagttagcac gcatttataa aggcgaacag cttcctgatc 23641 ttcgtctcca gtataaggac tacgctgtat ggcaaagcag acaggctgct gaagggtaca 23701 agaaggacca ggcttattgg aaggaagtct ttgcaggcga gctcccggtg cttcagcttc 23761 tgtccgatta cccaagacca cctgttcaaa gctttgaagg ggatcgggtg tcaatcaagc 23821 tggatgcggg ggtaaaggat cgcctcaatc gtttggctga acaaaacggc gccactttat 23881 atatggtgat gctgtccgct tactatacgc ttttgtcaaa gtatacgggg caggatgaca 23941 tcattgtcgg gacaccgtca gcgggcagaa atcactccga tacagagggc attatcggga 24001 tgttcgtcaa tacgcttgcg attcgcagtg aggtgaagca gaatgagacg tttacccaat 24061 tgatctcgcg tgtccgcaaa cgggtgctgg atgccttttc tcatcaggac tatccgtttg 24121 agtggcttgt tgaagatttg aacatcccgc gtgatgttag caggcatccg ctgtttgaca 24181 cgatgttcag ccttcaaaac gcgacagagg gcattccggc tgtcggcgat ctttccttgt 24241 ctgttcaaga gaccaatttc aagattgcca aatttgattt gacggtgcag gcgagagaaa 24301 ccgatgaagg cattgagatt gatgtggatt acagcacaaa gctgtttaaa caaagcacgg 24361 cagacaggct gcttacgcat tttgcgcgtt tgcttgaaga tgctgcggct gatccagaga 24421 agccgatttc cgagtataag cttctttctg aagaggaggc cgcttcgcaa attcagcagt 24481 ttaacccggg cagaacacct tatccgaaag ataaaacaat tgttcagctg tttgaggagc 24541 aagcggcgaa tacgccagac cacactgcgc ttcaatatga aggcgaatca ctcacttatc 24601 gtgaactgaa tgaacgggcc aatcgtttag cccgcggcat tctttctctt ggagctggcg 24661 aaggcagaac tgcggctgtc ttatgcgagc ggtcaatgga tatgattgtg tcgatcttgg 24721 cagtattaaa atcaggttcg gcttatgttc cgatcgatcc ggaacatccg attcagcgga 24781 tgcagcattt cttccgtgac agcggagcaa aggtgcttct cactcagagg aaattaaagg 24841 ctttggcgga agaagcggaa tttaagggcg ttatcgtgct agccgatgag gaagaaagct 24901 atcatgccga tgcgcgaaat ctcgcactgc ctcttgattc tgcagcaatg gccaacctga 24961 cgtatacttc cggaacgact ggaacaccta aggggaatat cgtgacacat gccaatattc 25021 tccgcacggt gaaggaaacg aattatctca gcattacaga acaggatacg attctcggtc 25081 tttccaatta cgtgtttgac gcgtttatgt tcgatatgtt cggctctttg ttaaacggag 25141 ccaagctggt gctgataccg aaggaaaccg ttttggacat ggctcgcctg tcccgcgtca 25201 ttgaacggga gaacatcagc attctcatga ttacaaccgc tttgttccac ttgcttgtgg 25261 acttgaatcc ggcatgcttg tcaacgcttc gcaagattat gtttggcggg gaacgggctt 25321 cggttgagca tgtcagaaaa gctttgcaaa cggttggaaa gggcaagctt cttcacatgt 25381 atggaccgtc tgaaagcacg gttttcgcga cgtatcatcc ggttgatgaa ttggaggagc 25441 acacgctgtc tgttccgatt ggaaaaccgg ttagcaatac ggaagtatac attcttgacc 25501 gtacgggaca cgtgcagcct gccgggattg ccggagagct ttgcgtcagc ggcgaaggac 25561 tcgtgaaagg ctattacaac cgtccagaac tgactgagga gaaatttgtt ccccatccgt 25621 ttacatccgg cgaacgcatg tataaaacgg gagaccttgc gagatggctg ccgaatggcg 25681 acatcgaatt tatcgggcga atcgaccatc aggtgaagat tcgcggacag cgcatcgagc 25741 ttggagaaat cgaacatcag ctgcaaaccc atgatcgtgt tcaggaaagt gttgtgcttg 25801 ccgttgatca aggagcggga gataaactgc tttgcgctta ctatgtcgga gagggagaca 25861 tctcatcaca agagatgaga gagcatgctg cgaaggactt gccggcatat atggttcctg 25921 cggtgtttat ccaaatggac gagctgccgc tgacagggaa cggaaaaatt gaccggagag 25981 cgctgccgat tcctgatgcc aacgtttcaa gaggtgtttc atatgttgcg cctcgtaatg 26041 aaatagaaca aaaagtcgca gacatttggg cacaggtact tcaggcagaa caagtcggcg 26101 cttatgacca cttctttgac attggcggac attcattagc aggcatgaag atgcttgcct 26161 tggttcatca ggaactgggc gttgagctgt cactcaagga tctcttccag tcaccgacgg 26221 ttgagggctt ggcacaggtg attgcctctg ctgaaaaagg gacagccgca agtatcagcc 26281 cggcagagaa acaagatacg tatcctgttt cttcaccgca aaaacggatg tacgtgcttc 26341 agcagcttga ggatgcgcaa acgagctata acatgccggc ggttctgcgc ctgacaggtg 26401 agcttgatgt tgaaaggctt aacagcgtca tgcagcagtt aatgcagcgt catgaagcct 26461 tgagaaccac gtttgaaata aaagatggag aaacggtgca gcggatctgg gaagaggctg 26521 agtgcgagat agcctatttc gaagccccgg aagaagagac agagcggatc gtttctgagt 26581 ttattaagcc tttcaaaatc gaccaacttc cactgttcag aatagggctt atcaagcatt 26641 cagacactga gcatgtgctg ctgttcgata tgcatcatat tatttctgat ggtgcatctg 26701 tcggtgtgct gattgaggag ctttcaaagc tgtacgacgg agaaaccctt gagccgctcc 26761 gtattcaata taaggattat gccgtgtggc agcagcagtt cattcagtct gagctttaca 26821 agaagcaaga agagcattgg ctggaggagc tggacggaga gctgccggtg ctgacgcttc 26881 cgactgatta cagtcggcct gccgttcaaa catttgaggg ggaccgcatt gcattttcat 26941 tagaagcagg caaagccgat gctctgcgca ggtttgcaaa agaaacggat tccacccttt 27001 acatggtgct tctggcttca tacagtgcgt ttttatcaaa acttagcggg caagacgata 27061 tcatcgtcgg ttcacctgtg gccggacgat ctcaagcgga cgtcagccgc gtcatcggaa 27121 tgttcgtcaa tacattggcg ctgcgcacgt atccgaaggg tgaaaagacg tttgctgact 27181 atcttaacga agtgaaagaa acggcactca gcgcttttga tgcgcaggat tacccgcttg 27241 aggatttgat cggaaatgtt ctggttcagc gtgacaccag cagaaatccg ttattcgatg 27301 cagttttttc aatgcaaaat gcgaatataa aggatttaac aatgaaaggg attcagcttg 27361 agccgcatcc gtttgaacgg aaaacagcca agtttgacct cacgctgacg gctgacgaaa 27421 ccgacggagg gcttacattc gtactcgaat acaatacagc tctgtttaag caggaaacga 27481 ttgaacgatg gaagcaatat tggatggagc ttttagatgc tgttaccggg aacccgaacc 27541 agccgctttc cagcctgtca ctggtcaccg agacagaaaa acaagcgctt cttgaggcat 27601 ggaagggcaa agcgctgcct gtgccgacag acaaaacggt tcatcagcta ttcgaagaga 27661 ctgcccagcg ccacaaagac cgccg //