LOCUS       gnlProkkaIFMEFEAN_14   14081 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IFMEFEAN_14.
ACCESSION   gnlProkkaIFMEFEAN_14
VERSION     gnlProkkaIFMEFEAN_14
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 19:05:32
            Original ID  :: gnl|Prokka|IFMEFEAN_14
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14081
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14081
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2469:4081]"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2470..4081
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     cand_cluster    1..14081
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14081
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="sactipeptide"
                     /region_number="1"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     CDS             complement(60..1730)
                     /locus_tag="ctg14_1"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLETPKDKTHGD
                     YSTNMAMQLARVAKKAPRQIAEEIVAHFDKGKASIEKLDIAGPGFINFYMNNQYLTKLI
                     PSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRF
                     VNEEESERLAFFREYGLKYELEKLRKDLENFRVPFDVWYSETSLYQNGKIDKALEALRE
                     KGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWG
                     ADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKP
                     AADLDFSHIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     CDS             complement(1727..2155)
                     /locus_tag="ctg14_2"
                     /transl_table=11
                     /translation="MKQETPITLHVKSVIEDDGNQEVIEFRTTGFYYVKQNKVYLSYYE
                     EHDLGKVKTIVKVSEGEVLVMRSGAVKMNQRFVKGASTIAKYKMSFGELELKTSTKSIQ
                     SDLDEEKGRISIAYDMHVGDEQEHLHNMTITYEGGTHA"
     CDS             2470..2601
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_functions="biosynthetic-additional (sactipeptides)
                     predicted sactipeptide"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_3"
                     /sec_met_domain="Subtilosin_A (E-value: 1.7e-30, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       2470..2499
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="ctg14_3_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       2500..2601
                     /prepeptide="core"
                     /locus_tag="ctg14_3_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="32.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[2469:2499](+)"
     CDS             2804..4081
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_4"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1022.7, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 2.3e-28,
                     bitscore: 90.8, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 6.1e-09, bitscore: 28.5,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.8e-23, bitscore: 76.0,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 9.1e-12, bitscore:
                     37.6, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 2.9e-11, bitscore: 36.1,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLEIDYLRDNVSISDFEYLDLNKTAYELCMRMDGQKTAEQILAEQ
                     CAVYDESPEDHKDWYYDMLNMLQNKQVIQLGNRAIRHTITTSGSNEFPMPLHATFELTH
                     RCNLKCAHCYLESSPEALGTVSIEQFKKTADMLFDNGVLTCEITGGEIFVHPNANEILD
                     YVCKKFKKVAVLTNGTLMRKESLELLKTYKQKIIVGISLDSVNSEVHDSFRGRKGSFAQ
                     TCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKVRDLGAKAFSYNWVDDFGRGRDII
                     HPTKDAEQHRKFMEYEQNVIDEFKDLIPIIPYERKRAANCGAGWKSIVISPFGEVRPCA
                     LFPKEFSLGNIFHDSYESIFNSPLVHKLWQAQAPRFSEHCMKDKCPFSGYCGGCYLKGL
                     NSNKYHRKNICSWAKNEQLEDVVQLI"
     CDS             4094..4255
                     /locus_tag="ctg14_5"
                     /transl_table=11
                     /translation="MSPAQRRILLYILSFIFVIGAVVYFVKSDYLFTLIFIAIAILFGM
                     RARKADSR"
     CDS             4252..4971
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 125.6; E-value:
                     4.3e-38)"
                     /gene_kind="transport"
                     /locus_tag="ctg14_6"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYERDNVILEQVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGRFTLCGIEAEAGMPQKTSDQQKTHRYFAADYPLLFTEITAKDYVS
                     FVHSLYQKDFSEQQFASLAEAFHFSKYINRRISELSLGNRQKVVLMTGLLLRAPLFILD
                     EPLVGLDVESIEVFYQKTREYCEAGGTILFSSHLLDVVQRFCDYAAILHNKQIQKVIPI
                     GEETDLRREFFEVIGHE"
     CDS             4964..6274
                     /locus_tag="ctg14_7"
                     /transl_table=11
                     /translation="MNNIIPIMSLLFKQLYSRQGKKDAIRIAAGLVILAVFEIGLIRQA
                     GIDESVLRKTYIILALLLMNAYMVFLSVTSQWKESYMKLSCLLPISSRSFWLAQSVVLF
                     VDTCLRRTLFFFILPLFLFGNGTLSGAQTLFWLGRFSFFTVYSIIFGVVLSNHFVKKKN
                     LMFLLHAAIFACVCLSAALMPAATLPLCAVHMLWAVVIDFPVFLQAPPQQSRMHSFMRR
                     SEFSFYKREWNRFISSKAMLLNYAVMAAFSGFFSFQMMNTGIFNQQVIYIVISALLLIC
                     SPIALLYSIEKNDRMLLITLPIKGKTMFWAKYRFYSGLLAGEFLLVVMIVGFISGRPIS
                     VLTFLQCIELLLAGAFIRLTADEKRPFFSWQTEQQLWSGFSKYRSYLFCLPLFLATLAG
                     TAVSLAVIPIAGLVIVYYLQKQDGGFFDTSKRERLGS"
     CDS             6240..7424
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg14_8"
                     /sec_met_domain="Peptidase_M16_C (E-value: 1e-06, bitscore:
                     21.2, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQAKENGLEVNLLKTHQFSTISIAASFLKPIESAAEPEEETIYF
                     YGAAAYLKEQIIDDFGCAAGSRFMYSANLFFDQQLKTCGTRLIHPLYNGNLHVDALMKT
                     FADLSFPSSLSFEAVEKARNELLLKIEKKFTDPFSYSAARLAEEVFGNPMYGTGMFGRK
                     DRIKAIHPKRFHDATDFIVDLVSQQKQLNILGQVQACDVRGHAPQTSAVTSERIPVNRH
                     VFETETRSAAGPSVLTLGFDCGEMKDASDYIKIQLIDGLLGKYGHSALFKHFREKDLAV
                     YHVITRYDVMNNLLLVSICTDQLHEIDIPPRVLEAVSAFHTDERELEQAKQFLRNELLL
                     QFDSPEGLLAYMGILRRFSCTKEALLDGISAVTCRDVLQFIATINYIGAHVVRG"
     CDS             7429..8709
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg14_9"
                     /sec_met_domain="Peptidase_M16 (E-value: 4.8e-15, bitscore:
                     48.2, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKAFFQQLDERTDIRYTDSGLKIFRLKFPRAHLRLCNVKIDFG
                     SRDVCIRAESGDTLLPYGTAHFLEHLLFWHNGRNLYSDFFAHGALLNAFTTYTDTNFMF
                     TSLPDRLRQTIPILLDALWNHSFDKKIVAQEKAVITSEIQTAHLNHQLSYHYQLISMLS
                     PSSPAAVFPAGRIEDIEALDISDLQKAYKAAYQTHRMTLFLIGGSENTETLLPPHLQLE
                     KRPDYHAERKIIPACPPALSQKMMLGDEERMEDTWTGLQIGALPGQNDLLTIKLYWDIA
                     ARILFQLDSPFFQEIQQTYRLEIDRLSAETYIYEDGGFLILHSQGTHSSAYIDVASYYV
                     TQKKEQAAAWLQYGKDSLTDAIIYDSDYVRKCFEWAAECDRCDCSFLDMYHIIQDMDAQ
                     VFLSLIDAMASSNKAIIHVSQKEAIRQ"
     CDS             8706..9407
                     /locus_tag="ctg14_10"
                     /transl_table=11
                     /translation="MKKNTVFTLLLLLIGMAAYSFGWVQAVAEAAAHYIQMINNDAVRL
                     GLLACTAALLMLPAFLYLHYVTQSVKNMTAAFQKLTQSHQSCCDFQQHNLCSRYAEDVK
                     SLRDGYKNVRQTYVMAAVLCQVIIFGCMFEIVKAVPFRLHTPPALSMGLAMLLILYLLF
                     CMRTYLRQLFRHGSLFRKVFAGVLAAAGIWWMLSFTISELLFLIILAAIQQIRSFIYKR
                     FSYRSTASLDL"
     CDS             complement(9413..10789)
                     /locus_tag="ctg14_11"
                     /transl_table=11
                     /translation="MKKNDLSALQENCFCFCDEEISREAPFQVPIDIPKGFKVDSAEAS
                     AAVTWSTDNLSCVSEPCLIQTGPETEDIGVRYAVRVQGTIMLLVSVSPVRNQYGQGDGA
                     VSVIHTEEIDQVVYYAAQSDRCPDFSQMTVEDLLIVPPFYGSPLTVAGTLVLPPSPDPQ
                     SYVFTANTGDSTVSVIDADLNTVVKTILFSAVPTNLGVTFDKAFTYVLHGNTNLVSVID
                     NKTLTIINTITVGGGPRKIEFDPTDEYAYVMAAGSIYMIDTANQSVIDVIAIPGALDFA
                     LDPNGQYVYTANGSSWSVDKYDVNTGQLVESIIDSFEFPSLIATPYAGNFAYVLNGELW
                     PKGVTEISLSPLSRGGDFNRLFETLRTIVFSLDSTRAYFLEPYSEPFLINNLYVVNTAR
                     QRIIANVPLPGAFDPAVTPDKQYIYAAQPNDNAVTVYRTSDYTAVKVIPVGAGPSAIVM
                     "
     CDS             complement(10828..11313)
                     /locus_tag="ctg14_12"
                     /transl_table=11
                     /translation="MFAYVLNFGLVQKVDLSTGEVTGTIERELIVSSIETDSPERYAYV
                     LEQEFLFNYLTVIDLNTFTISNTQELEPDGQYRMFTSGTGVYLYDDFTGNLYSVSPNGA
                     GVIGNLPQSATDYAFTPNGDFLYATRFIEQSIIVYNTDDYSEETVISLGVSPGAITI"
     CDS             complement(11346..12179)
                     /locus_tag="ctg14_13"
                     /transl_table=11
                     /translation="MRKNKLSFKEKAGAEQEECLCFCEGEASREAKFQAPIELPEGFVV
                     DPAEAVANVTWNADSLSCVSDRCLIQTGPEPDEVGVQFAVRLQGTVTLLVSVSPVRNQY
                     GQGDGAVSVIHNAEIDQVVYYSDEPDDCPDISNITIENLVVVPPFYGSPLSVTGTIVLV
                     PEPEPVYAFTANPNDQSVSVIDTNTHTVVTTIALPYNPAGIEITPDKSAVFVLHPNNNV
                     ISVIDYDTLTVTATILLDQPPRLIRFIPNHEFAYVFTGTAIYVIGIDTLTVERSI"
     CDS             12409..13554
                     /locus_tag="ctg14_14"
                     /transl_table=11
                     /translation="MTGVISSSSIGEKINEWYMYIRRFSIPDAEYLRREIKQELDQMEE
                     DQDLHLYYSLMEFRHNLMLEYLEPLEKMRIEEQPRLSDLLLEIDKKQARLTGLLEYYFN
                     FFRGMYELDQREYLSAIKFFKKAESKLIFVKDRIEKAEFFFKMSESYYYMKQTYFSMDY
                     ARQAYEIYKENEAYNIRLLQCHSLFATNFLDLKQYEDAVSHFQKAYSMAEAEKQPQLMG
                     RTLYNIGLCKNSQSQYEDAITYFKRAIAVFEESNILPSLPQAYFLITQIHYKLGKMDKA
                     HEYHSKGMAYSQKAGDVIYLSEFEFLKSLYLSGPDEEAIQGFFDFLESKMLYADLEDFT
                     IDVAKYYHERKNFQKASAYFLKVEQVRQLIQGGVSLYEIEV"
     CDS             13538..13657
                     /locus_tag="ctg14_15"
                     /transl_table=11
                     /translation="MKLKSKLLLSCLALSTVFVATTIANAPTHQIEVAQRGMI"
     CDS             13755..14066
                     /locus_tag="ctg14_16"
                     /transl_table=11
                     /translation="MSLKSVRTHFTQWNRENDVTEFETSSATVEQAAETIGVSLSRIAK
                     SLSFRGEGDQVILIVAAGDAKIDNKKSRQTFGFKARMLSPNEVLEQTGHEIGGVCPIG"
ORIGIN
        1 acgtcgtttt ctctacaagc taaggacaaa gcccgaagac tttgtccttt tgatcgtgat
       61 tacatttttt ccggagccga tacgccgatc agctgaagcg cattgttcag cgtaatttgc
      121 gttgccttca ttaaagccag gcgcgcacgg cttttctctt cattttcagg gtcgatgact
      181 ttctctgcgt tgtagaagct gtgcagagca gaggccagat cataaatata gtttgtgaca
      241 cggtgcggaa ttcgtttttc cgctgcttcc gccactgcct ctgggaagcc gccgatcgtt
      301 ttcagcagat cgtattcttt ttctgattga atatggctga aatcaagatc cgccgccggt
      361 ttaagtccct gctcttcccc ttggcgaagc atgctgcaga ttcgggcatg tgcatattgt
      421 gcataataca cagggttttc gttagatgtt gatacagcaa gatctaagtc aaaatccata
      481 tgggtgtccg cacttcgcat cgcaaagaag taacgaacgg catccaagcc gacttcttca
      541 atcaggtcac gcatcgttac ggctttaccg gtccgtttgc tcattttcat tttctcgccg
      601 tttttgtaaa ggtgaacgag ctgaatgatt tctacttcaa gcgttccttt ttcatagccc
      661 agcgcttcga ttgccgcttt catacgcggg atgtagccgt ggtgatcggc gccccaaacg
      721 ttgatcagct tatcaaagcc gcggtcaagc ttgtccttat gatacgcgat atcaggaagc
      781 aggtacgtgt acgtgccgtc cttcttgatc aatacgcggt ctttatcatc gccaaacgtc
      841 gtggaacgga accaagtcgc gccgtcttct tcatagacat ggcctttttc gcggagcgct
      901 tcaagcgcct tgtcgatttt tccattttgg tacagtgaag tttctgaata ccacacatca
      961 aacggcacac ggaagttttc caagtccttg cgaagctttt ccagctcata tttcaggccg
     1021 tattcacgga aaaacgcgag gcgttcactt tcttcttcgt taacgaaacg atcaccgtat
     1081 tcctcagcga gacgctttcc gatcgcaatg atatcctcgc cgcggtagcc atcctccggc
     1141 atcggttttt ccaatccgag tgcttcaaag taacggactt caacagaaag cgccagattg
     1201 ttgatttggt tacccgcatc gttaatgtag tattcgcggc ttacatcgta acccgctttt
     1261 gaaagcacgt tgcacaagga atcgccgaca gccgccccgc gcgcatgccc gaggtgaagg
     1321 tctcccgtcg gattcgctga tacgaattct acctgaactc gttcaccgtt tccgatgttc
     1381 gtttccccgt atgcttcccc tgcttccagt acagacggaa tcagctttgt taaatattga
     1441 ttgttcatat agaaattgat aaaacccggg ccggcgatat ccagtttttc aatcgaagcc
     1501 tttcctttat caaaatgggc gacaatctct tcagcgattt ggcgcggcgc tttttttgcc
     1561 actcttgcca gctgcatcgc catattcgtt gagtagtcgc cgtgtgtttt atctttcggt
     1621 gtttctaaaa caacattggg aatctggctt tcttcagcca gtcccgcttt cagaacggcc
     1681 gctttgattt cttctttcag cacgtccttc atttgttccg caatgttcat gcgtgagttc
     1741 ctccctcata cgtgatcgtc atattatgta aatgctcctg ctcgtctccg acatgcatgt
     1801 catatgcgat gctgatacgg cctttttctt catcgagatc agattgaatc gattttgtgc
     1861 ttgttttcag ctcaagctca ccaaatgaca ttttatattt agcaattgtg gaagctccct
     1921 ttacgaaacg ctgattcatt ttgacagcgc ctgacctcat gaccaggact tcgccttcgc
     1981 ttactttcac aatcgttttg actttgccta agtcgtgttc ttcataataa gatagataca
     2041 ctttattttg ttttacatag taaaatccgg tggtgcggaa ttcgatgact tcttggtttc
     2101 cgtcatcctc gatcacagac ttcacatgga gtgttatcgg tgtctcttgc ttcattctga
     2161 cacgtccttt tcatcattcc actttgactt gaatagtata atcattcggt ttgtaaactt
     2221 caactgcttc tatcttacca tcattgctca tcagatttga agataaacct cataaaaagc
     2281 atttccttat atagaagaga aaatcatatc actaattacc tttagtaaat gttacatttt
     2341 tccgaaatct atcatttcct tttcacattt ttttcaaaat atatgtattg aattagtaat
     2401 ttgatagttt taagataaaa gtacaacata gatctgttag aaaaacaaaa aaaaagggag
     2461 gattcaatta tgaaaaaagc tgtcattgta gaaaacaaag gttgtgcaac atgctcgatc
     2521 ggagccgctt gtctagtgga cggtcctatc cctgattttg aaattgccgg tgcaacaggt
     2581 ctattcggtc tatgggggta aggatctccc aaaagggcat agtcattcta ctatgccctt
     2641 tttaagtaaa ttacaatttt taactaaaat ctacctcttg gatatacata cacaaccgtt
     2701 tttcatttga atcatatgta taggggatgg tattttgttt atagagcaga tgtttccatt
     2761 tattaatgaa agtgtaagag ttcaccagct tcctgagggc ggcgtgttag aaatcgacta
     2821 cttgcgcgat aatgtctcca tttctgactt tgagtatttg gatctcaaca aaacagctta
     2881 cgagctctgc atgcgcatgg atggccaaaa aacagctgag cagattttag ctgagcaatg
     2941 tgcagtgtat gatgaatcac cggaagacca taaagattgg tattacgaca tgctcaacat
     3001 gctccagaac aagcaggtta tccagcttgg aaaccgggcc atccgccata ccatcaccac
     3061 gagcggaagc aatgaatttc cgatgcccct gcacgccacc tttgaactga cgcaccgctg
     3121 taatttgaaa tgcgcccact gttatttgga aagctcgcct gaagcgctcg gcaccgtgtc
     3181 gattgagcaa ttcaaaaaaa cggctgatat gctgtttgat aacggtgtat tgacatgcga
     3241 aatcacaggc ggagaaattt ttgtccatcc aaacgccaat gagattcttg actatgtgtg
     3301 taaaaagttc aaaaaagtcg ctgtcttaac aaacggaaca ctcatgcgaa aagagagcct
     3361 ggagcttttg aagacttaca agcaaaaaat catcgtcggc atttctcttg atagtgtcaa
     3421 ttccgaggtc catgactcct ttagagggag aaaaggctct tttgcccaaa cttgtaaaac
     3481 gataaaattg ttgagtgacc acggtatatt tgtcagagtc gccatgtctg tcttcgaaaa
     3541 aaacatgtgg gaaatccacg atatggccca aaaggttcgg gatctcggag cgaaggcgtt
     3601 ttcttacaat tgggttgacg atttcggaag aggcagggat attatccatc caacgaaaga
     3661 cgccgagcag caccgcaagt ttatggaata cgagcaaaat gtgattgatg agtttaaaga
     3721 tctgattccg attattccct atgagagaaa acgcgcggca aattgcggcg ctggctggaa
     3781 gtccattgtg atcagcccgt tcggcgaagt acgtccttgc gccctctttc caaaggaatt
     3841 ttcattggga aatatttttc atgattccta tgaaagcatc tttaactccc ctctcgtcca
     3901 taaactgtgg caagcgcagg cgccgcggtt cagcgaacat tgcatgaaag acaaatgccc
     3961 gttcagcggc tattgcggag gctgttactt aaaagggctg aactctaaca aatatcaccg
     4021 aaaaaacatt tgctcttggg cgaaaaatga acaattagaa gacgtggtcc agcttattta
     4081 ggagggaaac gatttgtcac cagcacaaag aagaatttta ctgtatatcc tttcatttat
     4141 ctttgtcatc ggcgcagtcg tctattttgt caaaagcgat tatctgttta cgctgatttt
     4201 cattgccatt gccattctgt tcggaatgcg cgcgcggaag gctgactcgc gatgagcatt
     4261 ttggatatac acgatgtatc cgtttggtat gaacgggaca acgtcatctt agaacaagtg
     4321 gatttacatt tagaaaaagg cgccgtttac gggctgcttg gggtaaacgg cgccggaaaa
     4381 acgacactga ttaatacgct gacaggcgtg aaccgcaatt tcagcgggcg ctttacactg
     4441 tgcggaattg aagcggaggc cggcatgccg cagaaaacat cagatcagca gaagactcac
     4501 cgttacttcg ccgccgatta tccgctgcta tttacagaaa ttacggcgaa ggactatgtg
     4561 tctttcgtcc attcgcttta tcaaaaggat ttttcagagc agcagtttgc cagtttggcc
     4621 gaggcctttc atttttcgaa atacatcaac aggagaattt cggagctgtc cttggggaac
     4681 aggcaaaagg ttgtattgat gacaggctta ttgctgcgcg ctcccctatt tattttggat
     4741 gagccgctcg tcggtttgga tgtggaatcg atagaggttt tttatcagaa aacgcgcgag
     4801 tactgtgaag caggcgggac cattttgttt tcttctcatc tgctcgatgt cgtgcaaaga
     4861 ttttgtgatt acgcggccat tcttcacaac aaacagatcc aaaaggtcat tccgattgga
     4921 gaggagaccg atctgcggcg ggaatttttc gaggtgatcg gccatgaata acataatccc
     4981 catcatgtct ttgctgttca aacagcttta cagccggcaa gggaaaaagg acgccatccg
     5041 cattgccgca ggccttgtca ttctggccgt atttgaaatc gggctgatcc gccaggccgg
     5101 cattgatgaa tcggtgttgc gcaaaacgta tatcatactc gcgcttctct taatgaacgc
     5161 atatatggtg tttctttctg tgacatctca atggaaggaa tcttatatga aactgagctg
     5221 cctgctgccg atttcttcac ggagcttttg gctcgcccag agtgtcgttt tgtttgtcga
     5281 tacctgtttg agaagaacgt tattcttttt tattttaccg ctgttcttat ttggaaacgg
     5341 aacgctgtca ggggcgcaaa cattgttttg gctcggcagg ttttcgtttt ttaccgttta
     5401 ctccattatt ttcggagttg tgctaagcaa ccacttcgtc aaaaagaaga acttgatgtt
     5461 tctgctgcat gcggcgatat tcgcctgtgt atgtctcagc gccgctttga tgccggccgc
     5521 cacgcttccg ctttgcgcgg tgcatatgct gtgggcggtg gtcattgact ttcctgtctt
     5581 tctgcaggcg cctccgcagc agagcaggat gcattcattt atgcggcgat ctgagttttc
     5641 gttttacaaa agagaatgga accgatttat ctcttctaaa gcgatgctgt taaattacgc
     5701 ggtaatggcg gcgttcagcg gcttcttttc gttccagatg atgaataccg gcatcttcaa
     5761 tcagcaagtg atttatatcg tgatttccgc gcttctgctc atctgctcgc cgatcgccct
     5821 tttgtactcg attgaaaaaa atgaccggat gctgctcatc acgcttccga tcaaggggaa
     5881 aacgatgttt tgggcgaaat atcgctttta ttcaggccta ttggcaggcg aatttctcct
     5941 tgtcgtgatg attgtgggtt tcatcagcgg ccgtccgatt tcagttctca cttttttgca
     6001 gtgcattgag ttgctgctgg cgggagcttt tatcaggtta actgcggatg aaaaaaggcc
     6061 cttcttcagc tggcagacgg agcagcagct atggagcggt ttctcaaaat atcggtctta
     6121 tctgttttgt cttcccctat tcttagccac attagccggc accgctgtat ccttggcggt
     6181 cattccgata gccggtctgg tcatagtcta ttacctgcaa aaacaggatg gtggtttctt
     6241 tgatacaagc aaaagagaac ggcttggaag ttaacctgct gaagactcat caattttcaa
     6301 ctatatcaat cgccgcgagc tttctgaaac cgatcgaaag cgcggcggaa cctgaggaag
     6361 aaacgattta tttttacggc gccgccgcat acctgaagga gcaaatcatt gacgatttcg
     6421 gttgtgctgc cggcagccgt ttcatgtact cagcgaatct cttttttgat cagcagctga
     6481 aaacctgcgg gacccgtttg attcacccat tatataatgg gaatcttcat gttgacgccc
     6541 tgatgaaaac ttttgcagac ttgtctttcc cttcttctct ttcattcgaa gcagttgaaa
     6601 aggccaggaa tgagctgctg ctgaaaatcg aaaagaaatt cactgatccc ttctcctact
     6661 cggcggcgcg cttggctgag gaggtcttcg gaaacccgat gtacggcaca ggcatgtttg
     6721 gccggaaaga caggataaag gcgattcatc ctaaacggtt tcacgacgca acggacttta
     6781 tcgttgattt agtgtcccag caaaaacagc tgaacatatt gggacaagta caagcatgtg
     6841 atgttcgggg acatgccccg caaacgtccg ctgtaacgtc cgaaagaata cccgtaaacc
     6901 ggcatgtttt tgaaacagag acacgcagcg ctgcaggtcc ttccgtcttg acactcggat
     6961 ttgactgcgg agagatgaaa gatgccagcg attatatcaa aatacagcta atagacggat
     7021 tactgggaaa gtacggccat tccgctttat tcaagcactt cagagagaaa gatctggcag
     7081 tctatcacgt tatcacccgt tacgatgtca tgaacaattt gctgcttgtt tcaatatgta
     7141 cagatcagct tcatgagata gacattcccc cgcgcgtttt ggaagctgtc tcagcttttc
     7201 atacagatga gcgggaacta gaacaggcaa agcagttttt acgcaatgaa ttgctgctgc
     7261 aattcgattc tcccgaaggt ctattggcct atatggggat cctgcgccgc ttctcctgca
     7321 cgaaagaagc cttgctggat ggcatctcag cggttacatg ccgtgatgta ttgcaattca
     7381 tagcgaccat caattatatc ggagctcatg tagtaagggg atgaaaagat ggaaaagaaa
     7441 gccttttttc aacagctgga tgaacgaacc gatatcagat acacagacag cggactaaaa
     7501 atattcagat tgaaattccc ccgcgcccac ctgcggctgt gcaatgtaaa aatcgatttt
     7561 ggaagccggg atgtatgtat acgggcagaa tccggtgata cactgcttcc gtatggcaca
     7621 gcgcattttt tagagcatct tctcttctgg cataacggcc gcaatctgta cagtgatttt
     7681 tttgcgcatg gcgcgctttt aaacgcattc actacctaca ccgataccaa tttcatgttt
     7741 acctcattac cggatcggct cagacaaacg atccccatcc tgcttgatgc tttatggaac
     7801 cactcatttg acaagaagat tgtcgctcag gaaaaagctg tgattacaag cgaaattcaa
     7861 acagcacacc ttaaccatca gctctcatat cattatcagc tgatcagcat gctttctccc
     7921 tcctcaccag ctgccgtttt ccccgcaggc agaatcgaag atattgaggc gcttgacatc
     7981 agtgatttac aaaaagccta taaggctgcc taccaaaccc atcggatgac gctgtttttg
     8041 attgggggct cagaaaatac agaaacgcta ttgcctcctc acctccagct ggaaaagcgt
     8101 ccggattatc atgctgaaag aaaaatcatc ccggcatgcc ctccagccct ctcacaaaaa
     8161 atgatgctgg gtgatgagga gcggatggaa gatacatgga ccggattaca gatcggcgca
     8221 cttcccgggc aaaacgatct gttgacgatc aaactttatt gggatatcgc ggctcgtatt
     8281 ctatttcaat tagattcacc gttttttcaa gagattcagc aaacgtaccg cctggaaatc
     8341 gatcgtttgt cagccgagac ttatatctat gaggatggcg gtttcttgat ccttcacagt
     8401 caagggaccc attcttcagc ttatatcgat gtggcttcat actatgtcac acagaagaaa
     8461 gaacaggctg ccgcctggct tcaatacggc aaggactctt tgacagacgc gatcatttat
     8521 gacagcgatt atgtgcgtaa atgcttcgag tgggcagccg agtgtgacag gtgcgattgc
     8581 tcgtttcttg acatgtacca catcattcaa gatatggatg cgcaggtttt cttgtctctc
     8641 attgatgcaa tggcatcttc taacaaagcg atcattcacg tttctcagaa agaggcgatc
     8701 agacaatgaa aaaaaacact gtctttaccc ttttattgct gcttataggt atggcggctt
     8761 attccttcgg ctgggttcag gccgttgccg aagccgccgc ccactatata cagatgatca
     8821 acaatgatgc tgtacggctc ggactgctgg cttgtaccgc tgccctcctg atgctgcctg
     8881 cttttctcta tcttcactat gtcacccaat ctgtgaaaaa catgacagca gcttttcaga
     8941 aactcacaca gtctcatcaa agctgctgtg actttcagca acacaacttg tgcagccgat
     9001 atgcagaaga cgtcaaatcg ctgcgtgacg gctataaaaa cgtccgccaa acatacgtga
     9061 tggctgccgt gttgtgccaa gtcatcatat tcggctgcat gttcgaaatc gttaaagccg
     9121 tccctttccg ccttcacacg ccccctgccc tttcaatggg acttgcgatg ctactgatcc
     9181 tgtatttatt gttttgcatg cgaacgtatt tgcggcagct tttccggcac ggcagcctgt
     9241 tcagaaaagt gtttgcggga gtgctggcag cagccgggat ttggtggatg ctcagtttca
     9301 ctataagtga actgctgttt ctgattatcc tggctgccat ccagcaaatc agatcattta
     9361 tttataagcg attctcttat cgcagcaccg cttctcttga tctataaaat agctacatca
     9421 caatcgcaga cgggcccgcg ccaaccggaa tcaccttcac ggctgtataa tcacttgtgc
     9481 ggtacacagt cacagcattg tcgttgggct gtgccgcata aatatactgt ttgtccggcg
     9541 ttacggcggg gtcaaaagcg ccggggagag gcacgtttgc aatgatcctc tgtctggccg
     9601 tattaactac gtataagtta ttaatgagaa acggttcact atatggctct agaaaataag
     9661 ctctagtact atcgagagaa aatacaatcg tcctcagcgt ttcaaataaa cggttaaagt
     9721 cccctcccct gcttaatggt gacaaactaa tctccgttac acctttcggc cacagctcac
     9781 cattcaacac gtacgcaaaa tttccagcgt aaggagttgc aattaaactg ggaaattcaa
     9841 atgaatctat gatactttct accaactgcc cagtatttac atcatattta tcaaccgacc
     9901 aactgcttcc attagcggta tagacatact gtccattcgg atcaagagca aagtctaaag
     9961 cgccgggtat cgcgattaca tcaattactg attgattggc cgtgtcaatc atatatatag
    10021 atccggcggc catcacgtag gcgtactcat ctgttggatc aaattcgatc tttctcggtc
    10081 ctcctccaac agtaatggta tttatgatgg ttaatgtttt attatcaatc actgagacaa
    10141 ggttggtatt cccatggagg acatacgtga atgctttatc gaaagtaacg cctagattag
    10201 ttggcacagc agaaaacagg attgttttta caacagtgtt taaatctgca tcaatgaccg
    10261 aaaccgtgct gtctccagta ttggcagtaa acacatacga ttgagggtct ggcgatggcg
    10321 gcaaaacaag tgtcccggcc accgtgagcg gactgccgta gaaaggcggc acgatgagaa
    10381 gatcttccac tgtcatctga ctaaaatcag gacagcggtc agactgtgct gcataataaa
    10441 caacttgatc aatctcttca gtatgaatca cagaaaccgc cccgtctcct tgtccatatt
    10501 gatttcgcac aggcgacaca ctgacaagaa gcataatggt cccttgtact ctcacagcat
    10561 atcgaacacc aatatcttct gtttccggcc cagtctggat taagcaaggc tcactgacac
    10621 aggacaaatt gtctgtactc catgtaacag ccgctgacgc ttcggctgaa tcaaccttga
    10681 agcccttagg gatatctatt ggcacttgaa acggcgcttc ccggctaatt tcctcatcac
    10741 aaaaacagaa acaattttcc tgtaaagcag aaagatcatt ctttttcatg aattcacgtc
    10801 cttttaaaaa tgcacaacat gcagcggtta aatcgtaatg gcacccggtg aaaccccaag
    10861 agatatcaca gtttcctcag aataatcatc tgtgttgtaa acaatgatgc tctgctctat
    10921 aaaacgagtt gcatacagaa aatcgccatt cggggtaaac gcatagtctg ttgctgattg
    10981 cggaagattt ccaattacac ctgctccatt cggactgaca gaatataaat tgccggtaaa
    11041 gtcgtcatat aaatacacac ctgttccgct cgtaaacatt ctatattggc cgtcaggctc
    11101 cagttcttgg gtattgctga tcgtaaacgt atttaagtca ataaccgtca aataattgaa
    11161 taagaattct tgttctaaga catacgcata ccgctccgga gaatctgttt ctatggatga
    11221 tacgataagc tctcgttcaa tcgttcctgt gacttcaccg gtggataagt ccactttttg
    11281 cactaaccca aaattaagaa cataggcgaa caacccattg gggtcaattg caatatcaaa
    11341 accttctata tagacctctc aacagtcaac gtatcaattc caatcacata aatggcagta
    11401 ccggtgaaaa cataagcaaa ctcatgatta gggataaatc taatcaatcg aggcggctga
    11461 tccagcaata tagttgctgt cactgttaat gtgtcataat cgatgacaga aatcacatta
    11521 ttgttgggat gtaagacaaa cacagcgctt ttatctggcg taatttcaat acctgccgga
    11581 ttgtacggaa gagcaatcgt tgtcacaaca gtatgggtgt ttgtatcaat cacagaaact
    11641 gattgatcat ttggattcgc tgtaaacgcg tagacgggtt ccggctccgg tacaagcaca
    11701 atcgtccccg tcaccgataa aggactgccg taaaacggcg gaacaacaac aaggttctca
    11761 atcgtgatgt tactgatatc cgggcaatca tccggttcat cggaataata gacgacttga
    11821 tcgatttctg cattgtgaat gacggaaaca gccccatccc cttgtccata ttgatttcgc
    11881 acaggtgaga cactgacgag cagcgtaacg gttccctgca gacgcactgc aaattgaaca
    11941 ccgacctcat caggctctgg ccccgtttga attaagcaac ggtcactgac acaagaaagg
    12001 ctgtctgcat tccacgtcac gtttgcaaca gcttcagccg gatcaacgac aaatccttca
    12061 ggtaattcaa tcggcgcttg aaacttggct tctcggcttg cttctccctc acaaaaacat
    12121 aagcactctt cttgttctgc tcctgctttt tctttaaagg aaagcttgtt ttttctcatt
    12181 ccttcacttc cttttcagac atacactgct cacgcagata taacagaata tggaagagta
    12241 acgtgtttgc ttgtacaaat tactgagggt aaaagcttct ttttgaaaat atatctccaa
    12301 acatgcggtg taacgaaaga aaaaattgcg gtttttttgc gcttctcaca agaatgttga
    12361 tgataaaata tgacatatat agaattatga agggagggat ttgcaaacgt gacaggtgtc
    12421 atatcttctt cttccatcgg agaaaagatt aacgaatggt atatgtacat acgccgattc
    12481 agcatacccg atgcagaata tttgcgacga gaaatcaagc aagagctgga tcaaatggaa
    12541 gaagatcaag accttcattt gtactattca ctgatggagt ttcggcacaa cctgatgctt
    12601 gagtaccttg aaccgttaga aaaaatgagg attgaggaac agccgagact gtctgatctg
    12661 ctgcttgaga ttgataaaaa acaggctcgt ttaacaggtc tgcttgagta ctattttaat
    12721 ttcttcagag gcatgtatga gctggatcag cgggaatatc tgtcggctat taaatttttc
    12781 aaaaaggccg aaagcaagct gatattcgtt aaggatcgga tagagaaagc tgagtttttc
    12841 tttaagatgt ctgaatctta ttactatatg aaacaaacgt atttttcaat ggactatgca
    12901 cggcaagcat atgaaatata caaagaaaat gaagcttata atataagatt gctgcagtgt
    12961 cattctttat ttgccaccaa ttttttagat ttaaaacagt atgaggatgc cgtctcacat
    13021 tttcaaaaag cttattctat ggcagaagct gaaaagcagc cccaattaat gggaagaact
    13081 ttgtacaata tcgggctttg taaaaacagc caaagccaat atgaggatgc cataacatat
    13141 ttcaaaagag caatagctgt ttttgaagaa tcaaatattc ttccttcctt acctcaagcg
    13201 tattttttaa ttacacagat ccattataaa ttaggaaaaa tggataaagc tcatgaatat
    13261 catagtaagg gaatggctta ttcacaaaag gccggagatg taatatattt atcagagttt
    13321 gaatttttga aatctttata cttatcaggc ccggatgaag aagcaattca aggatttttt
    13381 gattttctcg aaagtaaaat gttgtatgct gatcttgaag atttcactat tgatgtggca
    13441 aaatattatc atgaacgtaa aaattttcaa aaagcttctg cttatttttt gaaggtggaa
    13501 caagtaaggc aacttattca aggaggagtg agtttgtatg aaattgaagt ctaaactatt
    13561 actctcttgt ctggctctaa gcactgtgtt cgtggcaaca actattgcaa atgcacctac
    13621 acaccaaatt gaagttgcac aacgaggaat gatttaaccg ccgtccatcg gcggtttttt
    13681 tgtcccctct ttacccagtc tcccaatcca ttctatgatt ttttcaataa tcttaaaaat
    13741 agtggaaatg cagcatgtct ctaaaaagtg tgagaaccca ctttactcaa tggaatcgag
    13801 aaaatgatgt gacggagttc gaaacgtcga gtgcgacagt tgaacaggca gctgagacaa
    13861 tcggcgtaag cctgtctaga atcgccaagt ccctgtcctt cagaggggaa ggagatcagg
    13921 tgattctgat tgtggcagcc ggcgatgcca agatcgacaa caaaaagtcc aggcaaacat
    13981 ttggctttaa agcaagaatg ctctctccta atgaggtact ggagcagaca ggccatgaaa
    14041 ttggaggagt ttgcccaatt ggatagactc atgatcctga g
//
