LOCUS       gnlProkkaIFMEFEAN_46   13566 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IFMEFEAN_46.
ACCESSION   gnlProkkaIFMEFEAN_46
VERSION     gnlProkkaIFMEFEAN_46
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 19:05:32
            Original ID  :: gnl|Prokka|IFMEFEAN_46
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13566
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13566
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[2768:3566]"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2769..3566
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..13566
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13566
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene"
                     /region_number="1"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /tool="antismash"
     CDS             2..127
                     /locus_tag="ctg45_1"
                     /transl_table=11
                     /translation="MYYRRMDILRKNKGCRDFLDSLKRCSMHRFFICAPVGLLNT"
     CDS             complement(93..650)
                     /locus_tag="ctg45_2"
                     /transl_table=11
                     /translation="MKRKQLLYTEERKWEYGTILIEDGVCLIENGEGDILLADTLQHSP
                     IWVHHKGKWEQAGFQDQLVLACGEENISLSGGERIRYEKSVKRPLMALLDSLDDETFLA
                     FLQHLHSFGLSVFDCVFSYNKGVFSNTSAGQGVSFYHFSNDTAQCAMQHHYSNEGTGDR
                     FEWTASNGKRSIMYSAVQRGRK"
     CDS             820..2664
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177:asparagine synthase (glutamine-hydrolyzing)
                     (Score: 586.7; E-value: 8.6e-178)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_3"
                     /sec_met_domain="GATase_7 (E-value: 1.4e-48, bitscore:
                     155.4, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 2.1e-101, bitscore:
                     331.5, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGITGWVDFKKQLVQEKQTMDRMTDTLSKRGPDDSNVWGEHHVL
                     FGHKRLAVVDIEGGRQPMACTYKGDTYTIIYNGELYNTEDLRKELRARGHQFERTSDTE
                     VLLHSYIEWQEDCVDHLNGIFAFAVWDEKRNLLFAARDRLGVKPFFYTKEGSSFLFGSE
                     IKAILAHPDIKARVDRTGLSEIFGLGPSRTPGTGIFKGIKEIRPAHALTFSKDGLNIWR
                     YWNVESEKHTDSFDDTVANVRSLFQDAVTRQLVSDVPVCTFLSGGLDSSAITAIAAGHF
                     EKEGKAPLHTYSIDYEENDKFFQASAFQPNDDGPWIEKMTEAFGTTHHKCVISQKDLVD
                     HLEEAVLVKDLPGMADVDSSLLWFCREIKKDFVVSLSGECADEIFGGYPWFHTADVESG
                     FPWMRSTEERIKLLSDSWQKKLNLKEYVNAKYEETLAETPLLDGETGVDKARRQLFYLN
                     MLWFMTNLLDRKDRMSMGASLEVRVPFADHRLVEYVWNIPWEMKMHDNREKGILRKALE
                     GILPDDILYRKKSPYPKTHHPEYTKGVSEWLKTIRSQKDSVLHTLLDRKQLDQLLETEG
                     SSFKVPWFGQLMKGPQLIAHLAQIHTWFEAYRIDIDEG"
     CDS             2769..3566
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_4"
                     /sec_met_domain="phytoene_synt (E-value: 2.7e-31, bitscore:
                     100.2, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEIKEAYQQCGQIVSAREPACYKAFSFLPLKQRQAAWAVMAFCH
                     TAANADEKALSAIEAEAEDVFSGTYNGNHFLWKAFGHAYQTFTLDSKPFREFIAAQKAE
                     DKPFGNLDELLMHAYQTGGAAGLMLLPIMARRHQKQLTHAAGSLGLAIQLIRILRDIGT
                     GQQQKSRIPREVMQQFGYTEDDLQKGVVNKAFTMTWEYIAFEAEAYLEECQDALPLFPQ
                     YSQKTVKAALHLHRAVLEKIRAKQHDVFQHHFALTERSEADSL"
     CDS             complement(3604..4866)
                     /gene_functions="transport (smcogs) SMCOG1086:MATE efflux
                     family protein (Score: 326.6; E-value: 3.5e-99)"
                     /gene_kind="transport"
                     /locus_tag="ctg45_5"
                     /transl_table=11
                     /translation="MFMGNADTLMLSQYSDNSVAAVGVSNQILNLIIVMFSFIATGTTV
                     IISQFLGSRQKKEAMEVAYVSIGANFFISLAISAVVFFAAVPLLHMMGLSDALMPDAKV
                     FLQVVGGLSFIQALIMTFSAILKSYGYTKDTMFVTIGMNILNIAGNFVVIFGLFGFPVL
                     GVAGVAMSTSIARVIGLIAMIVIVNKRIQLKMSLKKVFHMHKEHLRKLLKIGIPSAGEQ
                     LSYNLSQMIVTYFIAIMGAQALTTKVYTQNITMFILLFGTAISQGTQILIGRYIGGKQF
                     DAAYERCMKSLYWALGIAAATSVLMTIFSKDLIGLFTQSPDIIATASLLIAMTIILEPG
                     RSFNVIIINSLRAAGDAKFPVYMAMISMWGIGLPLAYLFGIHLGFGLAGIWISFIADEW
                     VRGILMYRRWRSRIWIQKGMA"
     CDS             5095..5958
                     /gene_functions="regulatory (smcogs) SMCOG1287:AraC family
                     transcriptional regulator (Score: 62.6; E-value: 5.4e-19)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg45_6"
                     /transl_table=11
                     /translation="MPRILFTVPPFPVFIAAGEGVFKKGETHVKRVFSVFDLIYVKQGT
                     LYITENETSFSVEGGEYILLSPGLEHYGTKGSDEATSYYWLHFDEHRYEFTAKGGSNWS
                     ELQQEKGSFEEPARYGLALPRKGKVQRPQFMAQQFEKLIDYSAENSDLPLRKQILFEEL
                     MLHLQKEAFQIPSAKERVAWEAARYLQEHYKEKTTIKDLSLALHYHQDYVSRCMQQVLG
                     VTPAQYTNRVRMTEAKRLLSSTNDKMGVIAETVGMEDPTYFSKLFKQIEGISPIEYRKI
                     VSRKVQ"
     CDS             5976..6989
                     /gene_functions="regulatory (smcogs) SMCOG1078:LacI family
                     transcription regulator (Score: 365; E-value: 6.3e-111)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg45_7"
                     /transl_table=11
                     /translation="MKTTIYDVAKAAGVSITTVSRVINNTGRISDKTRQKVMNVMNEMA
                     YTPNVHAAALTGKRTNMIALVAPDISNPFYGELAKSIEERADELGFQMLICSTDYDPKK
                     ETKYFSVLKQKKVDGIIFATGIESHDSMSALEEIASEQIPIAMISQDKPLLPMDIVVID
                     DVRGGYEAAKHLLSLGHTNIACIIGDGSTTGEKNRIKGFRQAMKEAGVPIDESLIIQTR
                     FSLESGKEEAGKLLDRNAPTAIFAFNDVLACAAIQAARIRSIKVPDDLSIIGFDNTILA
                     EMAAPPLTTIAQPIKEMGRSVIELLAEAIEGKRKAKQKIVLPPELVVRHSTSPLNT"
     CDS             7199..8227
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079:oxidoreductase (Score: 210.6; E-value: 6.6e-64)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_8"
                     /transl_table=11
                     /translation="MEHQVRCAVLGLGRLGYYHAKNLVTSVPGAKLVSVSDLLKGRAEQ
                     VARELGIEKWSEDPYEVLEDIDIDAVIIVTPTSTHGDMIIKAAENGKQIFVEKPLTLSL
                     EESRAVSEKVKETGVICQVGFMRRFDPAYADAKRRIDAGEIGKPIYYKGFTRDQGAPPA
                     EFIKHSGGIFIDCSIHDYDIARYLLGAEITSVSGHGRILNNPFMEQYGDVDQALTYIEF
                     DSGAAGDVEASRTSPYGHDIRAEVIGTEGSIFIGTLRHQHVTILSAKGSSYDIIPDFQT
                     RFHEAYCLELQHFAECVRDRKTPIVTDIDATINLEVGIAATNSFRSGRPVQLDVKRAYT
                     GM"
     CDS             complement(8279..8788)
                     /gene_functions="other (smcogs) SMCOG1250:DinB (Score:
                     156.2; E-value: 1.2e-47)"
                     /gene_kind="other"
                     /locus_tag="ctg45_9"
                     /transl_table=11
                     /translation="MTDAKQFYDYHSWANKKIFTHIENLPEETAYQEVKSVFPSVSDVL
                     LHMCRADYIWLNVLSGVAYQEIIDSAGKLESAQGNMAAIKQHAAELESQYHDFFSRQTD
                     LEQTFTMQHPKLGTLESTYADTILHVVNHGTYHRGNVTAMLRQLGHSGAPTDYMYYLYE
                     KRESKG"
     CDS             complement(8838..9449)
                     /locus_tag="ctg45_10"
                     /transl_table=11
                     /translation="MNAIIHGIVLAFGLILPLGVQNVFIFQQGAWQKHIWRALPAVISA
                     SVCDTLLIVLAVAGVSVIVQELPVFETVMMAGGFLFLLYMGWVTWNSRPNTSQNEKHTF
                     TPKKQVAFAAAVSLLNPHAILDTIGVIGTSSLQYSGLEKWLFMAACIAVSWIWFISLAI
                     AGRLFQTIDTSGRLMLIVNKCSAAVMWAAAGYFGVSLFCN"
     CDS             9708..11021
                     /NRPS_PKS="Domain: Aminotran_1_2 (74-415). E-value:
                     1.3e-34. Score: 111.7. Matches aSDomain:
                     nrpspksdomains_ctg45_11_Aminotran_1_2.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 308; E-value: 1.6e-93)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_11"
                     /sec_met_domain="Aminotran_1_2 (E-value: 9.9e-35, bitscore:
                     111.7, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQVNRSTVTAAIDELTSQGLLEGRRGGGTKVVNSTWSVLAAEPP
                     LDWSDYVRSGIHRANSSIIQAINQNEPRADIIRLGTGELSPDLVPADTIGRMFQQINPG
                     VLSLGYEQPKGNRQLREAVADHLKGKKIHVSPSAILIVSGALQALQLISIGLLKRDSVI
                     LTEKPSYLQSLHVFQSAGMRLRGLPMDDEGVKAGLVSSNRKQYGGQLLYTIPSFHNPTG
                     TVMSEQRRKEIISLSKIEQLPIIEDDAYGDLWFEEKPPQPLKAMDHEGNILYLGTFSKT
                     VSPGLRIGWLAGPEPVIERLADIKMQTDYGSSGLSQWAAAEWLSQGYYEEHLTWVRRKL
                     KERRDAAVHFLERYAGDIATWRIPAGGFYIWVTFHKNLPVSRFFYGLLKRQVLVNPGYI
                     YDGEDRNSIRLSYSYASLGDLETGIKAAAETARRLMMS"
     aSDomain        9930..10952
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg45_11_Aminotran_1_2.1"
                     /evalue="1.30E-34"
                     /label="ctg45_11_Aminotran_1_2.1"
                     /locus_tag="ctg45_11"
                     /protein_end="415"
                     /protein_start="74"
                     /score="111.7"
                     /tool="antismash"
                     /translation="DIIRLGTGELSPDLVPADTIGRMFQQINPGVLSLGYEQPKGNRQL
                     REAVADHLKGKKIHVSPSAILIVSGALQALQLISIGLLKRDSVILTEKPSYLQSLHVFQ
                     SAGMRLRGLPMDDEGVKAGLVSSNRKQYGGQLLYTIPSFHNPTGTVMSEQRRKEIISLS
                     KIEQLPIIEDDAYGDLWFEEKPPQPLKAMDHEGNILYLGTFSKTVSPGLRIGWLAGPEP
                     VIERLADIKMQTDYGSSGLSQWAAAEWLSQGYYEEHLTWVRRKLKERRDAAVHFLERYA
                     GDIATWRIPAGGFYIWVTFHKNLPVSRFFYGLLKRQVLVNPGYIYDGEDRNSIRLSYSY
                     A"
     CDS             complement(11029..11667)
                     /gene_functions="other (smcogs) SMCOG1286:Pentapeptide
                     repeat protein (Score: 35.4; E-value: 7.8e-11)"
                     /gene_kind="other"
                     /locus_tag="ctg45_12"
                     /transl_table=11
                     /translation="MNKIAIQKPNIPENLQTADFHDAVTQDDVISMHLFEDCTICGEDI
                     ERLCVEKTVFRNVVFIDVSFRHIELTDVIFEKCDLSNADFSGAVIHRTSVKQSKMVGMN
                     VAEATLRNVSFEECHGHFSSFSYSNMKQVRFDHCALMQSECSNTVLQQTHFDGCELEGA
                     SFTGTSLQNMDISTCRFEQLHVSLDKLKGCKIAPEHAIAFARALGAVIV"
     CDS             11873..12679
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036:alpha/beta hydrolase fold protein (Score: 125.9;
                     E-value: 4.1e-38)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_13"
                     /sec_met_domain="PF00561 (E-value: 8.5e-25, bitscore: 79.3,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.1e-19, bitscore:
                     62.4, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGHYVKTEEHVTLFVEDIGHGRPIIFLHGWPLNHKMFEYQMNELP
                     KRGFRFIGVDLRGYGQSDRPWEGYDYDTMADDVKAVIYTLQLENAILAGFSMGCAIAIR
                     YMARHEGADVDKLILLSAAAPAFTKRPGYPYGMRKQDIDDMIELFKADRPKTLADLGEQ
                     FFEKKVSPELRQWFLNLMLEASSYGTIHSGIALRDEDLRKELAAIKVPTLILHGRKDRI
                     APFDFAKELKRGIKQSELVPFANSGHGAFYEEKEKINSLIAQFSNS"
     CDS             complement(12674..13120)
                     /locus_tag="ctg45_14"
                     /transl_table=11
                     /translation="MDVVDELIELHEEHVSGLLRLCRQAGWPDYGEQELALLVQQGRFF
                     GYQNVSGDIISCIGLFLFGRLASIGLVIVDKEYQRLGLGRRMVNACITQTDENTAIRLC
                     ATKEGLPLYEKAGFHTAGSVRKYSCHSFQPYTKKLDSQMSGFFL"
ORIGIN
        1 attttattac agaagaatgg atattttaag gaaaaataaa ggctgtcgag attttctcga
       61 cagcctgaag cggtgctcga tgcaccgctt ttttatttgc gcccccgttg gactgctgaa
      121 tacataatgg atcgctttcc gtttgaagcc gtccattcaa aacggtctcc tgtcccttcg
      181 ttgctgtagt gatgctgcat cgcgcattgt gcggtgtcat ttgaaaagtg ataaaaggac
      241 acaccctgcc ccgccgaagt attcgaaaag actcctttat tataagaaaa gacgcaatcg
      301 aataccgata agccgaagct gtgcaagtgc tgcagaaatg cgagaaaggt ttcgtcgtca
      361 agcgaatcca aaagcgccat gagcggccgc ttgactgatt tctcatagcg gatgcgttct
      421 cccccggaaa gggagatgtt ttcttcaccg catgccagaa ccaattgatc ctggaagccg
      481 gcttgctccc actttccttt atgatggacc cagattgggc tgtgttggag agtgtccgcc
      541 aaaagtatat caccttctcc gttttcgatt aaacagacgc cgtcttcgat gaggatggtg
      601 ccgtattccc attttcgttc ctctgtatat aacaattgtt tccgtttcat ccatgctgtc
      661 tcctttttct tcattcctct cttttctttc caattcaagc ctgtcccata caactctttt
      721 atggacaaat caactatctg cctatagatg cataaactta ctaaggtgct gaaagaaacg
      781 aaattgttac gaaagaaacg ggattggagc tgatgtcaca tgtgtggaat tacgggttgg
      841 gtcgatttta aaaagcagct cgtccaggaa aaacaaacga tggacagaat gacagacact
      901 ctttccaaac gagggcctga tgattcaaac gtttgggggg agcaccatgt tttattcgga
      961 cataaaagac ttgcggttgt tgatattgaa ggaggacgcc agccgatggc gtgtacctat
     1021 aaaggggata cgtacaccat tatttacaat ggcgagctgt ataacacgga agatttgcgc
     1081 aaagaattgc gggcgcgggg ccatcaattc gagcgtacgt cagataccga ggtgcttctg
     1141 cacagctaca tcgagtggca ggaagactgt gtcgaccatc tcaatggcat attcgctttc
     1201 gctgtgtggg atgaaaagcg taatctgctg tttgccgcga gagaccgtct cggtgtaaag
     1261 ccattttttt acacgaagga aggctcttca tttctcttcg ggtcggaaat caaagcaatc
     1321 ctcgcgcacc ctgatataaa agcgcgagtg gacagaacgg gactttctga aattttcggt
     1381 cttggaccgt ccagaacccc gggcactggc atatttaaag gtataaaaga aatccgcccg
     1441 gctcatgcgc tgacattttc caaagacgga cttaatattt ggcgttattg gaatgttgaa
     1501 agcgaaaaac atacggacag ttttgatgac acggttgcca atgtcagatc gttatttcag
     1561 gacgcggtga cgcggcagct tgtgtcggat gtgcctgttt gcacattcct atcaggcggt
     1621 ctggactcaa gcgcgattac agcgattgcg gcgggccatt ttgaaaagga aggaaaagca
     1681 ccgcttcata cttattcgat tgattacgaa gagaacgata aattttttca agcaagcgct
     1741 tttcagccga atgatgacgg accatggatt gaaaaaatga cagaggcttt cggcacaacg
     1801 caccacaaat gcgtcatcag ccaaaaagat ctcgttgatc atttggagga agctgtactg
     1861 gtcaaagact tgccgggaat ggcggatgtc gactcatccc tgctgtggtt ttgccgggaa
     1921 atcaaaaagg actttgtcgt cagcctatcg ggagagtgcg cggatgagat tttcggcggg
     1981 tacccgtggt tccatacggc agatgttgag tctggctttc catggatgag atcaacggag
     2041 gagcggatca agctgctttc tgactcatgg cagaaaaaat tgaatctgaa agaatacgta
     2101 aatgccaaat atgaagaaac cttggcagaa acgccattat tagatggtga aacgggtgtg
     2161 gataaagcaa gaagacagct gttctattta aatatgcttt ggtttatgac gaaccttttg
     2221 gatcggaagg atcgcatgag catgggggcg agcctggaag tgcgggtgcc gttcgccgat
     2281 caccggcttg tggaatatgt ttggaatatt ccgtgggaaa tgaaaatgca tgataatcgg
     2341 gaaaaaggca ttttacgcaa agcgcttgaa ggtattttgc ctgatgacat tctgtatcgc
     2401 aaaaaaagcc cgtatccgaa aacacatcat ccggaatata caaaaggcgt cagcgaatgg
     2461 ctgaaaacga tcagaagcca aaaggactcc gtgctccata ccttgctgga cagaaaacaa
     2521 ttagatcagc ttttagaaac ggaaggctcc tccttcaagg tgccgtggtt cggacagctc
     2581 atgaagggac ctcagctgat cgcccatctt gctcaaattc atacatggtt tgaagcgtat
     2641 cgcattgata ttgatgaagg ataaagaaaa agccgattct gctcaaagga atcggctttt
     2701 tcttcatata caattgcgag aaaacataat agacttgaag aagcagtgat acataggagt
     2761 gaacagaaat gaaagagata aaagaagcct atcagcaatg cggccagatc gtcagcgccc
     2821 gcgaaccagc ctgttacaaa gcattttcgt ttcttccgct gaagcaaagg caggcagctt
     2881 gggcggttat ggcgttttgc catacggcag ccaatgcgga tgagaaggcg ttatctgcca
     2941 ttgaagcgga ggcggaagat gttttttccg gtacgtataa cgggaatcat tttttgtgga
     3001 aggctttcgg ccatgcgtac caaaccttta cactggacag caagccattc cgtgagttca
     3061 ttgccgcaca gaaagcggaa gataaaccgt ttggaaacct tgatgaattg ctcatgcacg
     3121 cataccagac aggcggcgca gccggattga tgctgctccc gattatggcg cgccggcatc
     3181 agaaacagct gacacatgca gccggttctc tcggtttagc gattcagctg attcggattc
     3241 tgagagatat cggcactggc caacagcaaa aaagccgtat ccctcgggaa gtgatgcagc
     3301 aatttggata tacagaggac gaccttcaaa aaggcgtcgt gaataaggcg ttcacaatga
     3361 cgtgggagta tatcgctttt gaagcagaag cctaccttga agagtgtcag gatgccttgc
     3421 cgctatttcc gcagtattct caaaaaacgg tgaaagccgc tcttcatttg caccgggctg
     3481 ttttagaaaa aatccgggcg aagcagcacg atgtatttca acatcacttc gctctcacag
     3541 agagaagtga agcagattct ctctgatatc taaaaaaaca cccggtcttg attgagccgg
     3601 gtgttatgcc ataccttttt gaatccaaat acgtgagcgc catcttctgt acattaagat
     3661 tccccggacc cattcatccg cgataaaaga aatccaaatg ccggcaagac cgaaaccgag
     3721 atggatgccg aaaagataag caagcgggag gccgatgccc cacattgaaa tcattgccat
     3781 gtaaaccggg aatttcgcat cccccgcagc ccgcagagag ttaatgataa tgacattaaa
     3841 cgagcggcct ggttcaagaa taatggtcat ggcaatcaat aggcttgcag ttgctataat
     3901 gtcagggctt tgtgtgaaga gtccgatcag gtcttttgaa aagatcgtca tcaaaacaga
     3961 ggtagccgca gcaattccga gtgcccaata taagctcttc atgcagcgct cataagcggc
     4021 atcaaattgt ttgccgccga tataacggcc gattaagatt tgtgtaccct ggctgatcgc
     4081 agtgccgaac agcaaaataa acatcgtaat attttgcgta tacacttttg ttgtcaacgc
     4141 ctgcgcgccc atgatggcga taaaatacgt aacaatcatt tgcgaaaggt tgtatgaaag
     4201 ctgctctccc gcagaaggaa tgccgatttt cagcagcttg cgcaaatgct ctttatgcat
     4261 atgaaagact tttttcagcg acatcttcag ctggatgcgt ttgttgacaa tcacaatcat
     4321 cgcgattaat ccgatgacgc gggcgataga tgtggacatg gccacaccgg caacaccgag
     4381 aacaggaaag ccgaacaaac cgaaaatcac aacaaagttt ccggcaatgt ttaaaatgtt
     4441 catgccgata gtgacaaaca ttgtatcttt tgtgtagccg tagcttttta agatcgcgct
     4501 gaatgtcatg attaaagcct gaataaagga cagacctccg acaacttgta aaaagacttt
     4561 cgcatcaggc atcagtgcgt ctgataatcc catcatatga agcagaggga cagccgcgaa
     4621 aaagacgacg gcgctgatgg ccaggctgat gaagaagttg gcgccgattg acacataagc
     4681 gacttccatg gcttctttct tttgccgtga gcctagaaat tgtgaaatga taacggtcgt
     4741 tcctgttgcg ataaagctga acatcacgat aattaaattt aaaatctggt tgctgacgcc
     4801 gactgctgcc acgctgttat ccgagtattg gctgagcatc agtgtatcgg cattacccat
     4861 aaacatatat aatgagacct caataaagat cggccaagta agcgaaaata atgagaacgt
     4921 tttgtcagcg ggttttttca aagcagttga tttgaagaca gcttgtttca tagtgtctaa
     4981 cccctttcgt aaataaaatc aacgttttaa agtgtacctc catttcctta taataaaaag
     5041 ggatagaaac gatacttctt gtaaaaatcc gacttaaaaa ggaggatgat tcaaatgcct
     5101 cgcatcctgt ttacagtccc gccttttccg gtatttatcg cagctgggga aggggttttt
     5161 aaaaaaggag aaacccatgt gaaacgtgta ttctccgtgt ttgatctgat atatgtcaaa
     5221 cagggaacgt tatatataac ggaaaatgaa acatcgtttt ctgttgaagg cggcgagtac
     5281 atcttgcttt ctcccggtct tgaacactac gggacgaagg gcagtgatga agcaacctcc
     5341 tactattggc ttcacttcga tgaacatcga tatgaattta cggcaaaggg aggcagcaac
     5401 tggtctgagc ttcagcagga aaaagggagc ttcgaagagc cggcccgcta cggattggct
     5461 ttgccgagaa aaggcaaggt gcagcgcccg cagtttatgg cgcagcagtt tgaaaagctg
     5521 atcgattact ccgcggaaaa ctctgatttg ccgctcagaa agcaaatttt atttgaggag
     5581 ctgatgctgc atcttcaaaa agaagcgttc caaataccgt ctgcgaaaga gcgggtagcc
     5641 tgggaggcgg cccggtactt acaggagcac tataaggaaa agacgacaat caaggatctg
     5701 tcgctcgccc ttcactatca tcaggattat gtgagccgct gcatgcagca ggtgctcggc
     5761 gtaactccgg cacaatacac gaaccgggtg agaatgacgg aagcgaagcg tcttttatcc
     5821 tctacaaatg ataaaatggg cgttattgcg gaaacggtcg gaatggaaga tccgacatac
     5881 ttttcaaaac tctttaagca gatagaaggc atttcaccaa ttgaataccg gaaaattgtc
     5941 agccggaaag ttcaataacc agacgaggga tgaacatgaa aacaacaatt tacgatgtgg
     6001 caaaggcggc gggtgtctcg atcacaactg tgtcccgtgt gataaacaat acggggagaa
     6061 tcagcgataa aacacggcag aaggtcatga atgtcatgaa tgaaatggca tacacgccca
     6121 atgtccacgc cgcggcgtta acgggaaaac gaacgaatat gattgctctc gtggcgcctg
     6181 atatttcaaa tccgttttac ggcgaactgg ccaaaagcat tgaggaaaga gcggatgagc
     6241 tcggttttca aatgttgatt tgcagcaccg attacgatcc aaaaaaagaa acaaagtatt
     6301 tttctgtgct gaaacagaaa aaggtggatg gcattatttt tgcaacaggg attgaaagcc
     6361 atgacagtat gtctgctttg gaggaaatcg ccagtgaaca aattccgatt gccatgattt
     6421 ctcaggataa gccgcttctt ccgatggata ttgttgtgat agatgacgtt cgtggcggat
     6481 atgaggctgc caagcatctt ctgtcactcg gccacacgaa catcgcctgc attatcggag
     6541 acgggtcaac gacaggcgaa aaaaatagaa tcaaaggctt ccgtcaggcg atgaaggaag
     6601 cgggcgtgcc cattgatgaa tcacttatca tccagacgcg gttttccttg gaaagcggca
     6661 aggaagaagc gggaaaattg ctcgacagaa acgctccgac tgctattttt gccttcaacg
     6721 acgtattggc ttgtgccgcc atacaagctg cgagaataag aagcataaaa gtgccggatg
     6781 atctttctat cattggtttt gataatacga tactcgcaga aatggcggct ccgcccctga
     6841 caaccatagc ccagccgata aaagagatgg ggcggagcgt catcgaactg ctggcagaag
     6901 caatagaggg aaaacgaaag gcgaaacaaa aaatagtgct cccgcctgag cttgtagtca
     6961 gacattctac atcaccgctc aacacatgag cccgctaatg agcgggtttt ttcattatga
     7021 cagttgaagc aaaaaaaaac atattgcgtg taaaccaatg gcagtgtaaa atgaaaccat
     7081 cttttgagaa agcgcttgcg caaaatggca gagcggatag aaccgctgtt tttttagttg
     7141 ttaagagaaa gcgctttctc aaagcgagcc tgaaatgaga taaaggagag gatgggacgt
     7201 ggaacatcaa gtaagatgtg cagtattggg attaggaagg ctgggttatt atcatgcgaa
     7261 aaatctcgtc accagtgtgc cgggggcaaa gctggttagt gtcagtgacc tgttaaaagg
     7321 gagagcggag caggttgcca gagaactcgg tatcgaaaaa tggtcagagg acccgtatga
     7381 agtgttagaa gatattgaca ttgatgctgt cattatcgta acgccgacaa gcacacatgg
     7441 tgatatgatc atcaaagctg ccgagaacgg caaacagatc tttgttgaaa aaccgctgac
     7501 attaagcctt gaggaatcaa gagcagtttc tgaaaaagtg aaagagacag gtgtcatctg
     7561 ccaagtcggc tttatgagac ggttcgatcc agcatacgca gatgccaaac ggcggatcga
     7621 cgctggagaa atcggcaaac ctatctatta taaaggcttt acgcgcgacc aaggcgcgcc
     7681 tcccgcagaa tttatcaaac acagcggtgg aatttttatc gactgttcca tccatgacta
     7741 tgatattgcc cgttatttgc taggggcgga aattacttct gtttcaggac acggcaggat
     7801 tctgaacaat ccgtttatgg agcagtacgg cgatgtggat caggcgctga cgtatattga
     7861 atttgactcc ggcgcagcgg gggacgtcga ggcaagcaga acctctccat acggacatga
     7921 catccgggcg gaggtgatcg ggacagaggg cagtattttc attgggacat tgagacatca
     7981 acatgtgacc atcctttcgg ctaaagggag cagttatgat atcattccag actttcaaac
     8041 tcgttttcat gaagcctact gcttggagct tcagcatttt gccgagtgtg tccgggatcg
     8101 aaaaacaccg attgtgacag atattgatgc gacgatcaat ttagaagtgg gtatcgccgc
     8161 aaccaattcc tttcgaagcg gcaggccggt acagctagat gtgaagcgcg cttatacagg
     8221 tatgtaaaag ctaatatgtt gcattttagg ctttccgcaa aaaaaagcaa ggacattttt
     8281 agcccttgct ttctcttttc tcatataaat agtacatata atcagtaggt gcgccagaat
     8341 ggcccagctg tctcagcatg gcggttacgt ttcctctgtg gtaagtgccg tgattgacga
     8401 catgcaggat ggtgtctgca taggttgatt ccagtgtacc tagtttcgga tgctgcattg
     8461 tgaaggtctg ttctaagtcc gtctggcggc tgaagaaatc atgatactgt gactccagct
     8521 cggcagcgtg ctgtttaatc gctgccatat taccttgcgc ggactctaat ttgcctgcgc
     8581 tgtctataat ctcttggtag gccactcccg aaagaacatt cagccaaatg tagtcagccc
     8641 tgcacatatg aagcagcacg tcgctgacag aaggaaatac gctctttact tcttgatagg
     8701 cagtttcctc cggcaggttt tcgatatggg taaatatttt cttgtttgcc caagaatgat
     8761 agtcataaaa ctgttttgca tcagtcataa gcatgccccc ttttctaaga aattcgtttt
     8821 tttcatctgt ttctccttca attgcaaaag agtgacaccc caaaatatcc tgccgctgcc
     8881 cacattaccg ctgcagagca tttgtttacg atcagcataa gcctgccgct cgtatctatc
     8941 gtctgaaaca accggcccgc tattgcaagg ctgataaacc aaatccaaga cacagcgatg
     9001 caggcggcca taaagagcca tttctcaagc cccgaatatt gaagagagct cgtgccgatg
     9061 acgccgatcg tgtccagaat ggcatgcggg tttaaaagag aaacagcggc cgcaaatgca
     9121 acttgctttt ttggtgtgaa cgtatgtttc tcattttggc ttgtgttcgg acggctgttc
     9181 caagtcaccc agcccatata gagcaaaaat aaaaatccgc cggccatcat gactgtctca
     9241 aacacaggca gctcctgcac aatgacagac acgcccgcaa cggctaatac gattaacagg
     9301 gtatcgcaga ctgaagcact gatgacagct gggagagccc gccaaatatg cttttgccac
     9361 gcgccttgct gaaaaataaa cacattctgc actcccagcg gcaaaattaa gccaaacgcg
     9421 agcacaattc cgtgaatgat tgcattcatg ctgaaaaagc tcccttcaca tttttttcaa
     9481 tcataagaga gattgtcact aaagtctcca gccatttggt tgggttagga accagccaaa
     9541 tgtataatgt gtaaaaaagg gggggcatga ccttgtcgca atggcagcca agccgaaagt
     9601 cggatgttcc gctgcatcgg cagatcgaac aatatatgaa agacaagatt cttcacggag
     9661 agtgggctgt agggacgaaa atcccctcac agagaacgct ggccgacatg tttcaagtca
     9721 accgcagcac agtcacagca gccatagatg aactcacgtc tcaaggcttg ttagagggaa
     9781 gaagaggcgg cggtacgaag gttgtaaaca gtacttggag cgtgctggcg gctgagcctc
     9841 cgcttgattg gagcgattac gtccgttcgg gcattcatcg cgccaattct tccatcattc
     9901 aagctattaa tcagaacgaa ccaagagcgg atatcatcag attaggaact ggagaacttt
     9961 caccggatct tgtgcctgct gacacaattg gacggatgtt tcagcaaatc aatccgggcg
    10021 tcctgtcttt aggatatgag cagccgaaag gaaaccgtca gctgcgggag gcagtggccg
    10081 accatttaaa aggaaagaag atccatgtgt caccgtctgc aattttaatt gtgtccggtg
    10141 cacttcaggc acttcagctc atctcaattg gacttttaaa acgagattct gtcattttga
    10201 cggagaagcc gtcctacctt caatccttgc atgtatttca atcagctggg atgcggcttc
    10261 gcggcttgcc gatggatgat gaaggggtca aagcggggct tgtttcttct aatcgaaaac
    10321 aatatggagg acagctgctt tacacgattc cgtcgtttca taatccgaca ggcacagtca
    10381 tgtcagagca gcgaaggaaa gagatcatca gcctgtcaaa aatagagcag ctgcccatca
    10441 ttgaggatga tgcgtacggt gatttatggt ttgaagaaaa accgccgcag ccgttgaaag
    10501 caatggatca tgagggcaat attctgtatc tgggcacgtt ttcaaaaacg gttagccccg
    10561 gcctgcgaat cggctggctt gccggtccgg agccggttat tgaaaggttg gcggacatta
    10621 aaatgcagac agactacgga tcaagcggcc tgtcccagtg ggcggctgcc gagtggctgt
    10681 cacaggggta ttatgaagag catctgactt gggtacgcag gaagcttaaa gaaaggagag
    10741 acgccgccgt tcattttctc gagcggtatg ccggggacat tgccacgtgg cggattcccg
    10801 caggcggctt ttatatttgg gtgacatttc acaaaaacct gcctgttagc cgtttctttt
    10861 atggattgct gaaacggcag gtgcttgtga atcccggcta tatttatgac ggtgaagacc
    10921 gaaacagcat caggctgtca tattcctatg catctcttgg agatttggaa actggcatta
    10981 aagcggcagc tgaaacagca cgccgcctga tgatgtccta ggctttggtt atacgatgac
    11041 agctcccagt gccctggcga aggcaatcgc atgctcaggt gcgattttgc agcctttcaa
    11101 tttgtcgagg gagacatgaa gctgttcaaa acggcacgtg ctgatgtcca tgttttgaag
    11161 ggatgtgccg gtaaagctgg cgccttccaa ttcgcatccg tcaaagtgtg tctgctggag
    11221 caccgtattg ctgcattcac tttgcataag agcacaatga tcaaatcgaa cttgtttcat
    11281 atttgaatac gaaaatgagc tgaaatgtcc gtggcattcc tcgaatgaaa cattccgaag
    11341 cgttgcttcc gccacattca ttccaaccat ttttgactgc ttaactgaag ttctgtgaat
    11401 gacagccccg ctgaaatcgg cgtttgataa atcgcacttt tcaaagatca catcggtcag
    11461 ttcaatatgc cgaaaagaca catcgataaa gacgacattt ctgaataccg ttttttcaac
    11521 acagagtctt tcgatatctt cgccgcagat ggtacaatct tcaaacaaat gcatgctgat
    11581 tacatcatcc tgcgtcacgg catcatgaaa atctgcggtt tgcaggtttt ccggtatgtt
    11641 cggtttttga attgcgattt tattcatgtg atgacatcct ttgctgtccg aaaaacagag
    11701 gcttccgggt tcaatttaat agatcgttaa ggaaattgat acatatagta aatcgtgaag
    11761 agccttttct tggtacagca gcccgcttgt tttgtaagca taaatggaaa gcttcctata
    11821 cgtcaaggcg tttacagggc gaaaaagcca aagggaacag gaggaatgcg gaatggggca
    11881 ttacgtcaaa accgaggagc atgtgacact gtttgtagag gatatcggac atggaaggcc
    11941 gatcatcttt ttgcacgggt ggccgttgaa tcataagatg tttgaatatc aaatgaatga
    12001 gcttccgaaa aggggatttc gttttatcgg cgttgatttg cggggatatg ggcaatctga
    12061 ccgcccttgg gaaggctacg attatgacac gatggccgat gatgtgaaag cagtcattta
    12121 tacgctgcag cttgagaatg cgattcttgc cggtttttca atgggctgcg ccattgcaat
    12181 ccgttatatg gcaaggcatg aaggagccga tgttgataag ctgattttac tgtctgcggc
    12241 agcccccgcg tttacaaaac gcccgggtta tccgtacggg atgaggaagc aggatattga
    12301 cgatatgatt gaattgttca aagctgatcg gcccaaaaca ctggctgatt taggggaaca
    12361 gttttttgag aaaaaagtgt ctccagagct taggcagtgg tttctcaatc tgatgctgga
    12421 ggcttcctcc tacgggacga tccactcggg catcgcatta agagatgaag atctcagaaa
    12481 ggaacttgct gcaatcaagg tgccgacgct gatcctgcac gggagaaagg atagaattgc
    12541 gccgtttgat tttgcgaaag aattgaagcg cggcatcaaa cagtcggaat tggttccgtt
    12601 tgcaaacagc gggcacggag cattttatga ggaaaaagag aagattaaca gtttgattgc
    12661 gcagttctcc aactcataag aaaaaacccg acatttgaga atcaagcttt tttgtataag
    12721 gttgaaaact gtgacagctg tactttcgca ctgaaccagc cgtatgaaaa cctgcttttt
    12781 cataaagcgg caaaccttct tttgtggcgc aaagcctgat ggcggtgttt tcatccgttt
    12841 gggtgataca ggcgtttacc atacgccggc cgagaccgag ccgttgatat tccttgtcaa
    12901 cgataacgag gccgatagaa gcaagacggc caaacaaaaa caagccgatg caggaaataa
    12961 tatcaccgct gacattttga tagccgaaaa agcgtccttg ctggacaagc agtgccagct
    13021 cttgttcgcc gtaatccggc cacccggctt gcctgcaaag ccgcaataag ccggaaacat
    13081 gttcttcatg aagctcaatc agctcatcca ctacatccat aagatcacct gcttgttcct
    13141 agtgttttgt acatgacaat atgagtgcct atgccgggaa tctcaaacgg ttcgccgagt
    13201 tcttcccacc caagttttga atagtagcct ttcacatggc ttctggcatt gcaccagacc
    13261 gcctgaacgc cgttctccgc cagtttctct tccgagtgtt tgatcagcgt gctcccgcct
    13321 ttttgatcgc gatatcctac aagcgttgcc atgcctctca gccgatatgc tggggattct
    13381 gttattaatg gctgaatttg cggggaaaaa gaggcgatgc tgatcagctt tccttcaaaa
    13441 aacgcgccga gatgaaagga gccttttgca tgatcctctt catatttgca ttgttcaatg
    13501 gattgatggg gacgcagaat gcggtgccgg atttcatacg tatcttccgc ggaaatggtt
    13561 ttgact
//
