LOCUS       gnlProkkaFLGMFOMJ_51   14143 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FLGMFOMJ_51.
ACCESSION   gnlProkkaFLGMFOMJ_51
VERSION     gnlProkkaFLGMFOMJ_51
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 19:11:48
            Original ID  :: gnl|Prokka|FLGMFOMJ_51
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 83015
            Orig. end    :: 97158
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14143
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:11612]"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11612
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     cand_cluster    1..14143
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14143
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="sactipeptide"
                     /region_number="1"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     CDS             complement(524..1669)
                     /locus_tag="ctg51_86"
                     /transl_table=11
                     /translation="MTGVISSSSIGEKINEWYMYIRRFSIPDAEYLRREIKQELDQMEE
                     DQDLHLYYSLMEFRHNLMLEYLEPLEKMRIEEQPRLSDLLLEIDKKQARLTGLLEYYFN
                     FFRGMYELDRREYVLAIQFFKKAESKLVFVKDKIDKAEFFFKMSEVYYYMKQTYVSMDY
                     ARQAFEIYSEQTTYDIRMIQCQSLFGANFLDLKQYEKAIAHFQKAFTLAKTEQQPQLMG
                     RTLYNIALCKQNQNSFESAIEYVKKSIQVFEGSKMLPSLPQAYFLITQIYFKLGKIDNA
                     CEYHKKGKEYSAAAGDTVYLTEFEFLESLYLSGPDEERIEKCFVFLESKMMYADIEDFA
                     LDVAKYYHQQENYKKASHYFLKVEEARQHIQGGVNLYEMEV"
     CDS             1899..3254
                     /locus_tag="ctg51_87"
                     /transl_table=11
                     /translation="MRKNKLSFKEKAGAEQEECLCFCEGEASREAMFQAPIELSEGFVV
                     DPAEAVANVTWNADSLSCVSDRCLIQTGPEPDEVGVQFAVRLQGTVTLLVSVSPVRNQY
                     GQGDGAVSVIHNAEIDQVVYYSDEPDDCPDISDITIENLVVVPPFYGSPLSVTGTIVLV
                     PEPEPVYAFTANPNDQSVSVIDTNTHTVVTTIALPYNPAGIEITPDKSAVFVLHPNNNV
                     ISVIDYDTLTVTATILLDQPPRLIRFIPNHEFAYVFTGTAIYVIGIDTLTVERSIPVEG
                     FDIAIDPNGLFAYVLNFGLVQKVDLSTGEVTGTIERELIVSSIETDSPERYAYVLEQEF
                     LFNYLTVIDLNTFTISNTQELEPDGQYRMFTSGTGVYLYDDFTGNLYSVSPNGAGVIGN
                     LPQSARDFAFTPNGDFLYATRFIEQSIIVYNTDDYSEETVISLGVSPGPITI"
     CDS             3293..4669
                     /locus_tag="ctg51_88"
                     /transl_table=11
                     /translation="MKKNDLSALQENCFCFCDEEISREAPFQVPIDIPEGFKFDSAEAS
                     AAVTWGTDNLSCVSEPCLIQTGPETEDIGVRYAVRVQGTIMLLVSVSPVRNQYGQGNGA
                     VSVIHTEEIDQVVYYAAQSDRCPDFSQMTVEDLLIVPPFYGSPLTVAGTLVLPPSPDPQ
                     SYVFTANSGDSTVSVIDADLNTVVKTILFSAVPTNLGVTFDKAFTYVLHGNTNLVSVID
                     NKTLSIINTITVGGGPRKIEFDPTDEYDYVMAAGSIYMIDTANQSVIDVIAIPGALDFA
                     LDPNGQYVYTANGSSWSVDKYDVNTGQLVESIIDSFEFPSLIATPYAGNFAYVLNGELW
                     PKGVTEISLSPLSRGGDFNRLFETLRTIVFSLDSTRAYFLEPYSEPFLINNLYVVNTAR
                     QRIIANVPLPGAFDLAVTPDKQYIYAAQPNDNAVTVYRTSDYTAVTVIPVGAGPSAIAM
                     "
     CDS             complement(4675..5376)
                     /locus_tag="ctg51_89"
                     /transl_table=11
                     /translation="MKKSTVFTLLFLLIGMAAYSFGWVQAVAEAAAQYVQMINNDAVRL
                     GLLACTAALLMLPAFLYLHYVTQSVKNMTAAFQKLTQSHQSCCDFQQHNLCSRYAEDVK
                     SLRDSYKNVRQTYVMAAVLCQVIIFGCMFEIVKAVPFRLHTPPALSMGLAMLLILYLLF
                     CMRTYLRQLFRHGSLFRKVFAGALAAAGIWWMLSFSISELLFLIILATIQQIGSFIYKR
                     FSYRSTASLDL"
     CDS             complement(5373..6653)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg51_90"
                     /sec_met_domain="Peptidase_M16 (E-value: 2.1e-14, bitscore:
                     46.4, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKAFFQQLDERTDIRYTDSGLKIFRLKFPRAHLRLCNVKIDFG
                     SRDVCIRAESGDTLLPYGTAHFLEHLLFWHNGRNLYSDFFAHGALLNAFTTYTDTNFMF
                     TSLPDRLRQTIPILLDALWNHSFDKKIVAQEKAVITSEIQTAHLNDQLSYHYQLISMLS
                     PSSPAAVFPAGRIEDIEALDISDLQKAYKAAYQTHRMTLFLIGGSENTETLLPPHLQLE
                     KRPDYHAERKIIPACPPALSQKMMLGDEERMEDTWTGLQIGALPGQNDLWVIKLYWDIA
                     ARILFQLDSPFFQEIQQTYRLEIDRLSAETYIYEDGGFLILHSQGTHSSAYIDVASYYV
                     TQKKEQVAAWLQYGKDSLTDAIIYDSDYVRKCFEWAAECDRCDCSFLDMYHIIQDMDAQ
                     VFLSLIDAMASSNKAIIHVSQKEAIRQ"
     CDS             complement(6658..7842)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg51_91"
                     /sec_met_domain="Peptidase_M16_C (E-value: 1.3e-06,
                     bitscore: 21.2, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQAKENGLEVNLLKTHQFSTISIAASFLKPIESAAEPEEETIYF
                     YGAAAYLKEQIIDAFGCAAGSRFMYSANLFFDQQLKTCGTRLIHPLYNGNLHVDALLKT
                     FADLSFPSSLSFEAVEKARNELLLRIEKKFTDPFSYSAARLAEEVFGNPMYGTGMFGRK
                     DRIKAIHPKRFLDATDFIVDLVSQQKQLNILGQVQACDVRGHAPQTSAVTSERIPVNRH
                     VFETETRSAAGPSVLTLGFDCGEMKDASDYIKIQLIDGLLGKYGHSALFKHFREKDLAV
                     YHVITRYDVMNNLLLVSICTDQLHEIDIPPRVLEAVSAFHTDERELEQAKQFLRNELLL
                     QFDSPEGLLAYMGILRRFSCTKEALLDGISAVTCRDVLQFIATINYIGAHVVRG"
     CDS             complement(7808..9118)
                     /locus_tag="ctg51_92"
                     /transl_table=11
                     /translation="MNNIIPIMSLLFKQLYSRQGKKDAIRIAAGLVILAVFEIGLIRQA
                     GIDESALRKTYIILALLLMNAYMVFLSVTSQWKESYMKLSCLLPISSRSFWLAQSVVLF
                     VDTCLRRTLFFFILPLFLFGNGTLSGAQTMFWLGRFSFFTVYSIIFGVVLSNHFVKKKN
                     WMFLLHAAIFACVCLSAALMPAATLPLCAVHMLWAVVIDFPVFLQAPPQQSRMHSFMRR
                     SEFSFYKREWNRFISSKAMLLNYAVMAAFSGFFSFQMMNTGIFNQQVIYIVISALLLIC
                     SPIALLYSIEKNDRMLLITLPIKRKTMFWAKYRFYSGLLAGGFLLVVMIVGFISGLPIS
                     VLTFLQCIELLLAGAFIRLTADEKRPSFSWQTEQQLWSSFSKYRSYLFCLPLFLATLTG
                     TAVSLAVIPIAGLVIVYYLQKQDGGFFDTSKRERLGS"
     CDS             complement(9111..9830)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 124.3; E-value:
                     1.1e-37)"
                     /gene_kind="transport"
                     /locus_tag="ctg51_93"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYERDNVILEQVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGRFTLCGIEAEAGMPQKTSDQLKTHRYFAADYPLLFTEITAKDYVS
                     FVHSLYQKDFSEQQFASLAEAFHFSKYINRRISELSLGNRQKVVLMTGLLLRAPLFILD
                     EPLVGLDVESIEVFYQKTREYCEAGGTILFSSHLLDVVQRFCDYAAILHNKQIQKVIPI
                     GEETDLRREFFEVIGHE"
     CDS             complement(9827..9988)
                     /locus_tag="ctg51_94"
                     /transl_table=11
                     /translation="MSPAQRRILLYILSFIFVIGAVVYFVKSDYLFTLIFIAIAILFGM
                     RARKADSR"
     CDS             complement(10001..11347)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg51_95"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1080.6, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 1.2e-30,
                     bitscore: 98.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 7.9e-09, bitscore: 28.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.6e-23, bitscore: 75.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1.2e-11, bitscore:
                     37.5, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 3.9e-11, bitscore: 36.0,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIEQMFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLN
                     KTAYELCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQLGNRASR
                     HTITTSGSNEFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSIEQFKKTADMLFDN
                     GVLTCEITGGEIFVHPNANEILDYVCKKFKKVAVLTNGTLMRKESLELLKTYKQKIIVG
                     ISLDSVNSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKV
                     RDLGAKAFSYNWVDDFGRGRDIVHPTKDAEQHRKFMEYEQNVIDEIKDLIPIIPYERKR
                     AANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFNSPLVHKLWQAQAPRF
                     SEHCMKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     CDS             complement(11481..11612)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_functions="biosynthetic-additional (sactipeptides)
                     predicted sactipeptide"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg51_96"
                     /sec_met_domain="Subtilosin_A (E-value: 2.1e-30, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       complement(11583..11612)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="ctg51_96_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       complement(11481..11582)
                     /prepeptide="core"
                     /locus_tag="ctg51_96_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="33.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[11582:11612](-)"
     CDS             11926..12354
                     /locus_tag="ctg51_97"
                     /transl_table=11
                     /translation="MKQETPITLHVKSVIEDDGNQEVIEFRTTGFYYVKQNKVYLSYYE
                     EHDLGKVKTIVKVSEGEVLVMRSGAVKMNQRFVKGASTIAKYKMSFGELELKTSTKSIQ
                     SDLDEEKGRISIAYDMHVGDEQEHLHNMTITYEGGTHA"
     CDS             12351..14021
                     /locus_tag="ctg51_98"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLETPKDKTHGD
                     YSTNMAMQLARVAKKAPRQIAEEIVAHFDKGKASIEKLDIAGPGFINFYMNNQYLTKLI
                     PSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRF
                     VNEEESERLAFFREYGLKYELEKLRKDLENFRVPFDVWYSETSLYQNGKIDKALEALRE
                     KGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWG
                     ADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKP
                     AADLDFSHIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     CDS             complement(13985..14143)
                     /locus_tag="ctg51_99"
                     /transl_table=11
                     /translation="MHLKPDEYLKKLYKTKKLVEKTSFSLQAKDKVRRLCPFDRDYIFS
                     GADTPIS"
ORIGIN
        1 catgagccaa cccaaatggg caaacacctc caatttcatg gcctgtctgc tccagtacct
       61 cattaggaga gagcattctt gctttaaagc caaatgtttg cctgaacttt ttgttattaa
      121 tcttggcatc gccggctgcc acaatcagaa tcgcctgatc tccttcccct ctgaaggaca
      181 gggtcttggc gattctagtc gggcttacgc cgatcgtctc agctgtctgt tcaacactgt
      241 cgcgctcgac gtttcgaact ccgtcacatc attttctcga ttccactgtg taaagtgggt
      301 tctcacactt tacagagaca tgctgcattt ccactctctt caagattatt gaaaaaaatc
      361 acaacatgaa ttgggagatt gggtaaagag gggacaaaaa aaccgccgat ggacggcggt
      421 ttagatcatg gcgcgttgcg caacatcaaa atgttctgtt gatgaatttg atacttcgac
      481 tgtgataaat acagcactca cagctaaaca agcgagtaat aatttatact tccatttcat
      541 ataaattcac ccccccttga atgtgctgtc ttgcttcttc aacctttaaa aagtaatgag
      601 atgctttttt gtaattttcc tgttgatgat aatatttagc aacatcaagt gcgaagtcct
      661 caatatctgc atacatcatt ttactttcaa gaaaaacaaa acatttttct atccgttcct
      721 catccggtcc agacaagtat aaagattcca aaaattcaaa ctccgttaga tacacggtat
      781 ctcccgcagc tgcagaatac tcttttcctt ttttatgata ttcacaggcg ttatcaatct
      841 tacctaattt aaaataaatt tgtgtaatta ggaaataagc ttgtggcaat gaaggaagca
      901 ttttagatcc ttcaaatact tgaatagatt tttttacata ctctatcgct gattcaaaac
      961 tgttttggtt ttgcttgcag agtgctatgt tataaagtgt tcttcccatt aattggggct
     1021 gctgctctgt ttttgcaagt gtaaaggctt tttgaaaatg ggcaattgct ttttcgtatt
     1081 gttttaaatc caaaaagttg gctccgaata aggactggca ttgaatcatt ctgatatcat
     1141 atgtagtctg ttcactgtat atttcgaatg cttgacgtgc atagtccatg gagacataag
     1201 tttgtttcat ataataatag acttctgaca ttttgaaaaa gaattcagct ttatcgattt
     1261 tatctttgac aaaaaccagc ttgctctcag cttttttaaa gaattgaatg gctaatacat
     1321 attcacggcg atccagctca tacatgcctc tgaagaaatt aaaatagtac tcaagcagac
     1381 cagttaaacg agcctgtttt ttatcaatct caagcagcag atcagacagt ctcggctgtt
     1441 cctcaatcct cattttttct aacggttcaa ggtactcaag catcaggttg tgccgaaact
     1501 ccatcagtga atagtacaaa tgaaggtctt gatcttcttc catttgatcc agctcttgct
     1561 tgatttctcg tcgcaaatat tctgcatcgg gtatgctaaa tcggcgtatg tacatatacc
     1621 attcgttaat cttttctccg atggaagaag aagatatgac acctgtcact tttgcaaatc
     1681 cctcccttca taattctata tatgtcatat tttatcatca acattcttgt gagaagcgca
     1741 aaaaaaccgc aattttttct ttcgttatac cgcatgtttg gagatatatt ttcaaaaaga
     1801 agcgtttacc ctcagcaatt tgtacaagca aacacgttac tcttccatat tctgttatat
     1861 ctgcgtgagc agtgtatgtc tgaaaaggaa gtgaaggaat gagaaaaaat aagctttcct
     1921 ttaaagaaaa agcaggagca gaacaagaag agtgcttatg tttttgtgag ggagaagcaa
     1981 gccgagaagc catgtttcaa gcgccgattg aattatctga aggatttgtc gttgatccgg
     2041 ctgaagctgt tgcaaacgtg acgtggaatg cagacagcct ttcttgtgtc agtgaccgtt
     2101 gcttaattca aacggggcca gagcctgatg aggtcggtgt tcaatttgca gtgcgcctgc
     2161 agggaaccgt tacgctactc gtcagtgtct cacctgtgcg aaatcaatat ggacaagggg
     2221 acggggctgt ttccgtcatt cacaatgcag aaatcgatca agtcgtctat tattccgatg
     2281 aaccggatga ttgcccggat atcagtgaca tcacgattga gaaccttgtt gttgttccgc
     2341 cgttttacgg cagtccttta tcggtgacgg ggacgattgt gcttgtaccg gagccggaac
     2401 ccgtctacgc gtttacagcg aatccaaatg atcaatcagt ttctgtgatt gatacaaaca
     2461 cccatactgt tgtgacaacg attgctcttc cgtacaatcc ggcaggtatt gaaattacgc
     2521 cagataaaag cgctgtgttt gtcttacatc ccaacaataa tgtgatttct gtcatcgatt
     2581 atgacacatt aacagtgaca gcaactatat tgctggatca gccgcctcga ttgattagat
     2641 ttatccctaa tcatgagttt gcttatgttt tcaccggtac tgccatttat gtgattggaa
     2701 ttgatacgtt gactgttgag aggtctattc ctgtagaagg ttttgatatt gcaattgacc
     2761 ccaatgggtt gttcgcctat gttcttaatt ttgggttagt gcaaaaagtg gacttatcta
     2821 ccggtgaagt cacaggaacg attgaacgag agcttatcgt atcatccata gaaacagatt
     2881 ctccggagcg gtatgcgtat gtcttagaac aagaattctt attcaattat ttgacggtta
     2941 ttgacttaaa tacgtttacg atcagcaata cccaagaact ggagcctgac ggccaatata
     3001 gaatgtttac gagcggaaca ggtgtgtatt tatatgacga ctttaccggc aatttatatt
     3061 ctgtcagtcc gaatggtgca ggcgttatag gaaatcttcc gcaatcggca agagactttg
     3121 cgtttacccc gaatggcgat tttctgtatg caactcgttt tatagagcag agcatcattg
     3181 tttacaacac agatgattat tctgaggaaa ctgtgatatc tcttggggtt tcaccggggc
     3241 ctattacgat ttaaccgcta catgttgtgc atttttaaaa ggacgtgaat tcatgaaaaa
     3301 gaatgatctt tctgctttac aggaaaattg tttctgtttt tgtgatgagg aaattagccg
     3361 ggaagcgccg tttcaagtgc cgatagatat ccctgagggc ttcaagtttg attcggccga
     3421 agcgtcagcg gctgttacat ggggtacaga caatttgtcc tgtgtcagtg agccttgctt
     3481 aatccagact gggccggaaa cagaagatat tggtgttcga tatgctgtga gagtacaagg
     3541 gaccattatg cttcttgtca gtgtgtcgcc tgtgcgaaat caatatggac aaggcaatgg
     3601 ggcagtttct gtgattcata ctgaagagat tgatcaagtt gtttattatg cagcacagtc
     3661 tgaccgctgt cctgatttta gtcagatgac agtggaagat cttctcatcg tgccgccttt
     3721 ctacggcagt ccgctcacgg tggccgggac acttgttttg ccgccatcgc cagaccctca
     3781 atcgtatgtg tttactgcta attctggaga cagcacggtt tcggtcattg atgcagattt
     3841 aaacactgtt gtaaaaacaa tcctgttttc tgctgtgcca actaatctag gcgttacttt
     3901 cgataaagca ttcacgtatg tcctccatgg gaataccaac cttgtctcag tgattgataa
     3961 taaaacattg agtatcataa ataccattac tgttggagga gggccgagaa agatcgaatt
     4021 tgatccaaca gatgagtacg actacgtgat ggccgccgga tctatatata tgattgacac
     4081 ggccaatcaa tcagtaattg atgtaatcgc gatacccggc gctttagact ttgctcttga
     4141 tccgaatgga cagtatgtct ataccgctaa tggaagcagt tggtcggttg ataaatatga
     4201 tgtaaatact gggcagttgg tagaaagtat catagattca tttgaatttc ccagtttaat
     4261 tgcaactcct tacgctggaa attttgcgta cgtgttgaat ggtgagctgt ggccgaaagg
     4321 tgtaacggag attagtttgt caccattaag caggggaggg gactttaacc gtttatttga
     4381 aacgctgagg acgattgtat tttctctcga tagtactaga gcttattttc tagagccata
     4441 tagtgaaccg tttctcatta ataacttata cgtagttaat acggccagac agaggatcat
     4501 tgcaaacgtg cctctccccg gcgcttttga cctcgccgta acgccggaca aacagtatat
     4561 ttatgcggca cagcccaacg acaatgctgt gactgtgtac cgcacaagtg attatacagc
     4621 cgtgacggtg attccggttg gcgcgggtcc gtctgcgatt gcgatgtagc tattttatag
     4681 atcaagagaa gcggtgctgc gataagagaa tcgtttataa ataaatgatc cgatttgctg
     4741 aatggtagcc aggataatca gaaacagcag ttcacttata gagaaactga gcatccacca
     4801 aatcccggct gctgccagcg ctcccgcaaa cacttttctg aacaggctgc cgtgccggaa
     4861 aagctgccgc aaataagttc gcatgcaaaa caataaatac agaatcagta gcatcgcaag
     4921 tcccattgaa agggcagggg gcgtgtgaag gcggaaaggg acggctttaa cgatttcgaa
     4981 catgcagccg aatatgatga cttggcacaa cacggcagcc atcacgtatg tttggcggac
     5041 gtttttatag ctgtcacgca gcgatttgac gtcttctgca tatcggctgc acaagttgtg
     5101 ttgctgaaag tcacagcagc tttgatgaga ctgtgtgagt ttctgaaaag ctgctgtcat
     5161 gtttttcacg gattgggtga cataatgaag atatagaaaa gcaggcagca tcaggagggc
     5221 agcggtacaa gccagcagtc cgagccgaac agcatcattg ttgatcatct gtacatattg
     5281 ggcggcggct tcggcaacgg cctgaaccca tccgaaggaa taagccgcca tacctataag
     5341 cagaaataaa agggtaaaga cagtgctttt tttcattgtc tgatcgcctc tttctgagaa
     5401 acgtgaatga tcgctttgtt agaagatgcc attgcatcaa tgagagacaa gaaaacctgc
     5461 gcatccatat cttgaatgat gtggtacatg tcaagaaacg agcaatcgca cctgtcacac
     5521 tcggctgccc actcgaagca tttacgcaca taatcgctgt cataaatgat cgcgtctgtc
     5581 aaagagtcct tgccgtattg aagccaggcg gcaacctgtt ctttcttctg tgtgacatag
     5641 tatgaagcca catcgatata agctgaagaa tgggtccctt gactgtgaag gatcaagaaa
     5701 ccgccatcct catatatata agtctcggct gacaagcgat cgatttccag acggtacgtt
     5761 tgctgaatct cttgaaaaaa cggtgaatct aattgaaata gaatacgagc cgcgatatcc
     5821 caataaagct ttatcaccca cagatcgttt tgcccgggaa gtgcgccgat ctgtaatccg
     5881 gtccatgtat cttccatccg ctcctcatca cccagcatca ttttttgtga gagggctgga
     5941 gggcatgccg ggatgatttt tctttcagca tgataatccg gacgcttttc cagctggagg
     6001 tgaggaggca aaagcgtttc tgtattttct gagcccccaa tcaaaaacag cgtcatccga
     6061 tgggtttggt aggcagcctt ataggctttt tgtaaatcac tgatgtccag cgcctcaata
     6121 tcttcgattc tgcctgcggg gaaaacggca gctggtgagg agggagaaag catgctgatc
     6181 agctgataat gatatgagag ctgatcgtta aggtgtgctg tttgaatttc gcttgtaatc
     6241 acagcttttt cctgagcgac aatcttcttg tcaaatgagt ggttccataa agcatcaagc
     6301 aggatgggga tcgtttgtct gagccgatcc ggtaatgagg taaacatgaa attggtatcg
     6361 gtgtaggtag tgaatgcgtt taaaagcgcg ccatgcgcaa aaaaatcact gtacagattg
     6421 cggccgttat gccagaagag aagatgctct aaaaaatgcg ctgtgccata cggaagcagt
     6481 gtatcaccgg attctgcccg tatacataca tcccggcttc caaaatcgat ttttacattg
     6541 cacagccgca ggtgggcgcg ggggaatttc aatctgaata tttttagtcc gctgtctgtg
     6601 tatctgatat cggttcgttc atccagttgt tgaaaaaagg ctttattttc catctcttca
     6661 tccccttact acatgagctc cgatataatt gatggtcgct atgaattgca atacatcacg
     6721 gcatgtaacc gctgagatgc catccagcaa ggcttctttc gtgcaggaga agcggcgcag
     6781 gatccccata taggccaata gaccttcggg agaatcgaat tgcagcagca attcattgcg
     6841 taaaaactgc tttgcctgtt ctagttcccg ctcatctgta tgaaaagctg agacagcttc
     6901 caaaacgcgc gggggaatgt ctatctcatg aagctgatct gtacatattg aaacaagcag
     6961 caaattgttc atgacatcgt aacgggtgat aacgtgatag actgccagat ccttctctct
     7021 gaagtgcttg aataaagcgg aatggccgta ctttcccagt aatccgtcta ttagctgtat
     7081 tttgatataa tcgctggcat ctttcatctc tccgcagtca aatccgagtg tcaagacgga
     7141 aggacctgca gcgctgcgtg tctctgtttc aaaaacatgc cggtttacgg gtattctttc
     7201 ggacgttaca gcggacgttt gcggggcatg tccccgaaca tcacatgctt gtacttgtcc
     7261 caatatgttc agctgttttt gctgggacac taaatcaacg ataaagtccg ttgcgtcgag
     7321 aaaccgttta ggatgaatcg cctttatcct gtctttccgg ccaaacatgc ctgtgccgta
     7381 catcgggttt ccgaagacct cctcagccaa gcgcgccgcc gagtaggaga aaggatcagt
     7441 gaatttcttt tcgattctca gcagcagctc attcctggcc ttttcaactg cttcgaatga
     7501 aagagaagaa gggaaagaca agtctgcaaa agttttcagc agggcgtcaa catgaagatt
     7561 cccgttatat aatgggtgaa tcaaacgggt cccgcaggtt ttcagctgct gatcaaaaaa
     7621 gagattcgct gagtacatga aacggctgcc ggcagcacaa ccgaaagcgt caataatttg
     7681 ctccttcagg tatgcggcgg cgccgtaaaa ataaatcgtt tcttcctcag gttccgccgc
     7741 gctttcgatc ggtttcagaa agctcgcggc gattgatata gttgaaaatt gatgagtctt
     7801 cagcaggtta acttccaagc cgttctcttt tgcttgtatc aaagaaacca ccatcctgtt
     7861 tttgcaggta atagactatg accagaccgg ctatcggaat gaccgccaag gatacagcgg
     7921 tgccggttaa tgtggctaag aataggggaa gacaaaacag ataagaccga tattttgaga
     7981 aactgctcca tagctgctgc tccgtctgcc agctgaagga gggccttttt tcatccgcag
     8041 ttaacctgat aaaagctccc gccagcagca actcaatgca ctgcaaaaaa gtgagaactg
     8101 aaatcggaag gccgctgatg aaacccacaa tcatcacgac aaggagaaat ccgcctgcca
     8161 ataggcctga ataaaagcga tatttcgccc aaaacatcgt tttccgcttg atcggaagcg
     8221 tgatgagcag catccggtca tttttttcaa tcgagtacaa aagggcgatc ggcgagcaga
     8281 tgagcaaaag cgcggaaatc acgatataaa tcacttgctg attgaagatg ccggtattca
     8341 tcatctggaa cgaaaagaag ccgctgaacg ccgccattac cgcgtaattt aacagcatcg
     8401 ctttagaaga gataaatcgg ttccattctc ttttgtaaaa cgaaaactca gatcgccgca
     8461 taaatgaatg catcctgctc tgctgcggag gcgcctgcag aaagacagga aagtcaatga
     8521 ccaccgccca cagcatatga actgcgcaaa gcggaagcgt ggcggccggc atcaaagcgg
     8581 cgctgagaca tacacaggcg aatatcgccg catgcagcag aaacatccag ttcttctttt
     8641 tgacgaagtg gttgcttagc acaactccga aaataatgga gtaaacggta aaaaacgaaa
     8701 acctgccgag ccaaaacatt gtttgcgccc ctgacagcgt tccgtttcca aataagaaca
     8761 gcggtaaaat aaaaaagaat aacgttcttc tcaaacaggt atcgacaaac aaaacgacac
     8821 tctgagcaag ccaaaagctc cgtgaagaaa tcggcagcag gcagctcagt ttcatataag
     8881 attccttcca ttgagatgtc acagaaagaa acaccatata tgcgttcatt aagagaagcg
     8941 cgagtatgat atacgttttg cgcaatgccg attcatcaat gccggcctgg cggatcagcc
     9001 cgatttcaaa tacggccaga atgacaaggc ctgcggcaat gcggatggcg tcctttttcc
     9061 cttgccggct gtaaagctgt ttgaacagca aagacatgat ggggattatg ttattcatgg
     9121 ccgatcacct cgaaaaattc ccgccgcaga tcggtctcct ctccaatcgg aatgaccttt
     9181 tggatctgtt tgttgtgaag aatggccgcg taatcacaaa atctttgcac gacatcgagc
     9241 agatgagaag aaaacaaaat ggtcccgcct gcttcacagt actcgcgcgt tttctgataa
     9301 aaaacctcta tcgattccac atccaaaccg acgagcggct catccaaaat aaatagggga
     9361 gcgcgcagca ataagcctgt catcaataca accttttgcc tgttccccaa ggacagctcc
     9421 gaaattctcc tgttgatgta tttcgaaaaa tgaaaggcct cggccaaact ggcaaactgc
     9481 tgctctgaaa aatccttttg ataaagcgaa tggacgaaag acacatagtc cttcgccgta
     9541 atttctgtaa atagcagcgg ataatcggcg gcgaagtaac ggtgagtctt cagctgatct
     9601 gatgttttct gcggcatgcc ggcctccgct tcaattccgc acagtgtaaa gcgcccgctg
     9661 aaattgcggt tcacgcctgt cagcgtgtta atcagtgtcg tttttccggc gccgtttacc
     9721 ccaagcagcc cgtaaacggc gcctttttct aaatgtaaat ccacttgttc taagatgacg
     9781 ttgtcccgtt cataccaaac ggatacatcg tgtatatcca aaatgctcat cgcgagtcag
     9841 ccttccgcgc gcgcattccg aacagaatgg caatggcaat gaaaatcagc gtaaacagat
     9901 aatcgctttt gacaaaatag acgactgcgc cgatgacaaa gataaatgaa aggatataca
     9961 gtaaaattct tctttgtgct ggtgacaaat cgtttccctc ctaaataagc tggaccacgt
    10021 cttctaattg ttcatttttc gcccaagagc aaatgttttt tcggtgatat ttgttagagt
    10081 tcagcccttt taagtaacag cctccgcaat agccgctgaa cgggcatttg tctttcatgc
    10141 aatgttcgct gaaccgcggc gcctgcgctt gccacagttt atggacgaga ggggagttaa
    10201 agatgctttc ataggaatca tgaaaaatat ttcccaatga aaattccttt ggaaagaggg
    10261 cgcaaggacg cacttcgccg aacgggctga tcacaatgga cttccagcca gcgccgcaat
    10321 ttgccgcgcg ttttctctca tagggaataa tcggaatcag atctttaatc tcatcaatca
    10381 cattttgctc gtattccata aacttgcggt gctgctcggc gtctttcgtt ggatggacaa
    10441 tatccctgcc tcttccgaaa tcatcaaccc aattgtaaga gaacgccttc gccccgagat
    10501 cccgaacctt ttgggccata tcgtggattt cccacatgtt tttttcgaag acagacatgg
    10561 cgactctgac aaatataccg tggtcactca acaattttat cgttttacaa gtttgggcaa
    10621 aagagccttt tctccctcta aaagagtcat ggacctcgga attgacacta tcaagagaaa
    10681 tgccaacgat gattttttgc ttgtaagtct tcaaaagctc caggctctct tttcgcatga
    10741 gtgttccgtt tgttaagaca gcgacttttt tgaacttttt acacacatag tcaagaatct
    10801 cattggcgtt tggatggaca aaaatttctc cgcctgtgat ttcgcatgtc aatacaccgt
    10861 tatcaaacag catatcagcc gtttttttga attgctcaat cgacacggtg ccgagcgctt
    10921 caggtgagct ttccaaataa cagtgggcgc atttcaaatt acagcggtgc gtcagttcaa
    10981 aggtggcgtg caggggcatc ggaaattcat tgcttccgct cgtggtgatg gtatggcggc
    11041 tggcccggtt tccaagctgg ataacctgct tgttctggag catgttgagc atgtcgtaat
    11101 accaatcttt atggtcttcc ggtgattcat catacactgc acattgctca gctaaaatct
    11161 gctcagctgt tttttggcca tccatgcgca tgcagagctc gtaagctgtt ttgttgagat
    11221 ccaaatactc aaagtcagaa atggagacat tatcgcgcaa gtagtcgatt tctaacacgc
    11281 cgccctcagg aagctggtga actcttacac tttcattaat aaatggaaac atctgctcta
    11341 taaacaaaat accatcccct atacatatga ttcaaatgaa aaacggttgt gtatgtatat
    11401 ccaagaggta gattttagtt aaaaattgta atttacttaa aaagggcata gtagaatgac
    11461 tatgcccttt tgggagatcc ttacccccat agaccgaata gacctgttgc accggcaatt
    11521 tcaaaatcag ggataggacc gtccactaga caagcggctc cgatcgagca tgttgcacaa
    11581 cctttgtttt ctacaatgac agcttttttc ataattgaat cctccctttt ttttttgttt
    11641 ttctagcaga tctatgttgt acttttatct taaaactatc aaattactaa ttcaatacat
    11701 atattttgaa aaatgtgaaa aggaaatgat agatttcgga aaaatgtaac atttcctaaa
    11761 ggtaattagt gatatgattt tctcttctat ataaggaaat gctttttatg aggtttatct
    11821 tcaaatctga tgagcaatga tggtaagata gaaacagttg aagtttacaa accgaatgat
    11881 tatactattc aagtcaaagt ggaatgatga aaaggacgtg tcagaatgaa gcaagagaca
    11941 ccgataacac tccatgtgaa gtctgtgatc gaggatgacg gaaaccaaga agtcatcgaa
    12001 ttccgcacca ccggatttta ctatgtaaaa caaaataaag tgtatctatc ttattatgaa
    12061 gaacacgact taggcaaagt caaaacgatt gtgaaagtaa gcgaaggcga agtcctggtc
    12121 atgaggtcag gcgctgtcaa aatgaatcag cgtttcgtaa agggagcttc cacaattgct
    12181 aaatataaaa tgtcatttgg tgagcttgag ctgaaaacaa gcacaaaatc gattcaatct
    12241 gatctcgatg aagaaaaagg ccgtatcagc atcgcatatg acatgcatgt cggagacgag
    12301 caggagcatt tacataatat gacgatcacg tatgagggag gaactcacgc atgaacattg
    12361 cggaacaaat gaaggacgtg ctgaaagaag aaattaaagc ggccgttctg aaagcgggac
    12421 tggctgaaga aagccagatt cccaatgttg ttttagaaac accgaaagat aaaacacacg
    12481 gagactactc aacgaatatg gcgatgcagc tggcaagagt ggcaaaaaaa gcgccgcgcc
    12541 aaatcgctga agagattgtc gctcattttg ataaaggaaa ggcttcgatt gaaaaactgg
    12601 atatcgctgg cccgggtttt atcaatttct atatgaacaa tcaatattta acaaaactga
    12661 ttccgtctgt actggaagca ggggaagcat acggggaaac gaacatcgga aacggtgaac
    12721 gggttcaggt agaattcgtg tcagcgaatc cgacgggaga ccttcacctc gggcatgcgc
    12781 gcggggcggc tgtcggcgat tccttgtgca acgtgctttc aaaagcgggt tacgatgtaa
    12841 gccgtgaata ctacattaac gatgcgggta accaaatcaa caatctggcg ctttctgttg
    12901 aagtccgtta ctttgaagca ctcggattgg aaaaaccgat gccggaggat ggctaccgcg
    12961 gcgaggatat cattgcgatc ggaaagcgtc tcgctgagga atacggtgat cgtttcgtta
    13021 acgaagaaga aagtgaacgc ctcgcgtttt tccgtgaata cggcctgaaa tatgagctgg
    13081 aaaagcttcg caaggacttg gaaaacttcc gtgtgccgtt tgatgtgtgg tattcagaaa
    13141 cttcactgta ccaaaatgga aaaatcgaca aggcgcttga agcgctccgc gaaaaaggcc
    13201 atgtctatga agaagacggc gcgacttggt tccgttccac gacgtttggc gatgataaag
    13261 accgcgtatt gatcaagaag gacggcacgt acacgtacct gcttcctgat atcgcgtatc
    13321 ataaggacaa gcttgaccgc ggctttgata agctgatcaa cgtttggggc gccgatcacc
    13381 acggctacat cccgcgtatg aaagcggcaa ttgaagcgct gggctatgaa aaaggaacgc
    13441 ttgaagtaga aatcattcag ctcgttcacc tttacaaaaa cggcgagaaa atgaaaatga
    13501 gcaaacggac cggtaaagcc gtaacgatgc gtgacctgat tgaagaagtc ggcttggatg
    13561 ccgttcgtta cttctttgcg atgcgaagtg cggacaccca tatggatttt gacttagatc
    13621 ttgctgtatc aacatctaac gaaaaccccg tgtattatgc acaatacgcg catgcccgta
    13681 tttgcagcat gcttcgccaa ggggaagagc agggacttaa accggcggca gatcttgatt
    13741 tcagccatat tcaatcagaa aaagaatacg atctgctgaa aacgatcggc ggcttcccag
    13801 aggcagtggc ggaagcagcg gaaaaacgaa ttccgcaccg tgtcactaac tatatttatg
    13861 atctggcttc tgctctgcac agcttctaca atgcagagaa agtcatcgac cctgaaaatg
    13921 aagagaaaag ccgcgcgcgc ctggctttaa tgaaggcaac gcaaattacg ctgaacaatg
    13981 cgcttcagct gatcggcgta tcggctccgg aaaaaatgta atcacgatca aaaggacaaa
    14041 gtcttcggac tttgtcctta gcttgtagag aaaacgacgt tttttctaca agcttttttg
    14101 ttttatacag tttctttaga tattcatcag gtttcagatg cag
//
