LOCUS       c00008_gnlPro..        22525 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BCHHBOED_8.
ACCESSION   c00008_gnlPro..
VERSION     c00008_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 21:04:42
            Original ID  :: gnl|Prokka|BCHHBOED_8
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 800461
            Orig. end    :: 822986
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22525
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[810461:812986]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12525
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..22525
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..22525
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Fumarate2succinate"
                     /region_number="3"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(52..159)
                     /locus_tag="ctg8_886"
                     /transl_table=11
                     /translation="MYLFGPAEQKGGKDLTPAIRVLEEKIRQMELMRSA"
     CDS             complement(192..989)
                     /locus_tag="ctg8_887"
                     /transl_table=11
                     /translation="VIYRIHKDTELRLRKEHKPLDSLSLDEMVLEDDYLAGKVCTPDKA
                     REWKTTYSKQCECVKQKKIAKLMAASGITEKFEKLLFGNFKLDGKPQMIKDAYECAVEY
                     FKDFEKIKGERANSIALLGQPGSGKTHLLTAIMNNLIKKKSTHCLYFPYVEGMSDLKND
                     FDQLETKLNAMRKADVLFIDDLFKPVDGKPRATEWQVEQIQSVVNYRYLNHKPLLISSE
                     LTTDDLLDVDEALGSRIYQMCKYYTVIIQGNRMELNHRLGDWD"
     CDS             complement(1024..1722)
                     /locus_tag="ctg8_888"
                     /transl_table=11
                     /translation="MNYLKEMNGFMNWLETNPLSATTQALWFHLLHINNKAGWREWFTT
                     SNTTLQAKIEISENTLIKHRKMLIDLKRIEYKPQGRKAGQYRLISFETPVSEQEPSEKP
                     VPELAPAPQETQEVDPKMKNAFELFENKVARSIGSIEAQRIGYMVDDYGEEKVMEAMKK
                     AFRNKGSNVGLSYIEAILSNPFSQKRKEKQQYGNKQSSQYRHSVPSNDEGSSSKIAFLG
                     NRTGRIRRKG"
     CDS             complement(1887..2729)
                     /locus_tag="ctg8_889"
                     /transl_table=11
                     /translation="MATNQTLKNSIQKKQNSAPGQQQGTTMKGLLSSPAVMNRFEEVLG
                     KRASQFTASILSLYNSENTLQKADPMSVISSAMVAATLDLPVDKNLGYAWIVPYKGRAQ
                     FQLGYKGYIQLALRTGQYKSINCIPVHEGELQKWNPLTEEIDIDFAKRESESVIGYAAY
                     FELLNGFRKTVYWTKAQVEKHKKKFSKSDFGWGKDWDAMALKTVLKSMLSKWGILSVEM
                     QKAVIEDNEERERIDITDEMSEPEIIDAEPSEEKPSAQDADPFDGKPVDISDDDLPFD"
     CDS             complement(2732..3682)
                     /locus_tag="ctg8_890"
                     /transl_table=11
                     /translation="MQAEVFASTADMSRDEWLLERRKGIGGSDASVILGINKWQTPFEL
                     WLDKTGQVPVSESGSEAAYFGSLLEDIVAKEFEIRSGKKVRRRKAMLRHPKHDFILANV
                     DRMIVGEKAILECKTTSAYNLKEWEDDEIPDSYIVQVQHYLGVLGPEYKKAYFAVLIGG
                     NKFVWKEIERDDELIAMIFQAEIEFWNEKVLGGKAPVLDGSSAAEEYLKQRYAEAEGGK
                     VVDLTSDNKTRIQQYLQLKEQINELSLQAKELENQIKHEMKEAEYGFIGNYQTSWKSVS
                     TNRIDSKKLKEQFPDVYEKVTKEVQFRRFGIKEVS"
     CDS             complement(3682..3870)
                     /locus_tag="ctg8_891"
                     /transl_table=11
                     /translation="MAKAVKVAFSERAEDQQRLRQVGGSIVFAKNGKAQFSFPSMDHYR
                     EWQRLGAEAYKRKVGLL"
     CDS             complement(3972..4166)
                     /locus_tag="ctg8_892"
                     /transl_table=11
                     /translation="MIENPMILNNWHDRLTEPETPKDFFGDEVTPVDDYVIDCGTLILR
                     ENLDRYLKQQLGFKFKNEQ"
     CDS             complement(4126..4299)
                     /locus_tag="ctg8_893"
                     /transl_table=11
                     /translation="MMVHFVHKPATALEVRAWCERIRNHRELHLIWDERTANYRKENMN
                     DRESNDSKQLAR"
     CDS             complement(4296..4553)
                     /locus_tag="ctg8_894"
                     /transl_table=11
                     /translation="MKLNQFLKSDEEVVKRKTDSVESLAELLLDSLEEGDYEEALDILG
                     SIKANIEDLKRISNKGRLYDAAIRLKQRGIDLSVVRRSLG"
     CDS             complement(4550..5119)
                     /locus_tag="ctg8_895"
                     /transl_table=11
                     /translation="MSNNPYKLDNLPKIMREVRKTMGFTQFQLGQLLGGKDQRYVSDVE
                     NGLTTLTPELCIKWFEICGAYEHIDLVHYLFRLHPRATAPVDPALNVSPSKALINFMKQ
                     TKESLEAAENIALWLANERPGRIEALPMADLKEILDLGPAVDTLFYALSRSHGLKMQEL
                     ADKWTRKALMDQVAMSKQEERKAMLV"
     CDS             complement(5176..5904)
                     /locus_tag="ctg8_896"
                     /transl_table=11
                     /translation="MNQIVFIEGNQAVTDSLTVAEVFGKRHADVIKSIETLNCSKDFAE
                     RNFSLSEYLDPTGRSLKKYLIKRDGLTFLVFGYTGAKAAVFKEKYIAEFNRMEAELQKM
                     TQPSYMIEDPVSRAKRWISEQEERQQLEQALKIQEPLVNFAQSCMAAEKSLLVRELAKL
                     ASKNGIMIGEKRLFQKLREWKMIMANKNEPYQEYIERGFFEIAQGVRQVNGTPKSWLTM
                     RITPKGQAFIINKLKKQQAS"
     CDS             complement(5951..6091)
                     /locus_tag="ctg8_897"
                     /transl_table=11
                     /translation="MAKQTKKKTTNIKMGKEYYGTMDREECFRKALEPYFTSKKELRLH
                     A"
     CDS             6216..6467
                     /locus_tag="ctg8_898"
                     /transl_table=11
                     /translation="MDFKKISDNAYLEWFTEHAGNLSMYGKEDLPEFMKDEKDVHLFLQ
                     KFAQDISLLTVKSYHSELAKKLKEYDIDLESLEIPNKK"
     CDS             complement(6406..6567)
                     /locus_tag="ctg8_899"
                     /transl_table=11
                     /translation="MNKAKVIASATNWTINEAANFIEKSSPGQVEFCLISCLEFLRIQG
                     RCRIPSVS"
     CDS             complement(6597..6773)
                     /locus_tag="ctg8_900"
                     /transl_table=11
                     /translation="MNQKKIDQLNDLLNGMSQSEWNRIKQHVDMLFSSKVAKVQFDDSE
                     LLEINLKREFRIS"
     CDS             complement(6784..7026)
                     /locus_tag="ctg8_901"
                     /transl_table=11
                     /translation="MYIKQKRQWLEKLRQEHKMTQKQVAEEAKIARTTYAMIESGSRNP
                     TPQVAKSIAGVLDFDWTYFFEDECHITCNLKTHTA"
     CDS             7169..7567
                     /locus_tag="ctg8_902"
                     /transl_table=11
                     /translation="MLGMRLKKLRKSKSLELNKEIKQEEVAKNIGVGRTTYAMYEQDKR
                     QPDYETLIKLADYYEVTTDFLLRGESQEAKDKIFNEEARRILEDPDTLVAAADGKITAS
                     ILEAAQRIIAEQLKSGRQPGDIKNGNKK"
     CDS             7702..7854
                     /locus_tag="ctg8_903"
                     /transl_table=11
                     /translation="MRLFLHSTANFEVKHSGFINQSSERKSKKTLNLVDKKREISLHYK
                     RGNYN"
     CDS             7851..8570
                     /locus_tag="ctg8_904"
                     /transl_table=11
                     /translation="LKKWLLGIGALTLSFSLAACNSEDSSAKDNKAKEEKTATKTEEKT
                     EDKTTAKKDSSTDSSAEEKYKFSNESGDFTMLAGYTNDQSDKAQGFITLDFQGFTLKFM
                     PVLVDLKLSDSMKQEEEFSGKDTIRAIMISTEAENTADHDVDYNGDITVITDTKEQLTA
                     DSGLLSNNPIVKTYQGKVKEEGYFLIPLKDQKSTPKELELRFTPPYKVENGAVNTETGL
                     MGKEQTVKVKYTSRESL"
     CDS             8711..9187
                     /locus_tag="ctg8_905"
                     /transl_table=11
                     /translation="LRYTNSHLEDWIEQLYKDINILKPHEINFDRIAQALDILIVYNPE
                     TSFALRFNGMYTISLDSRKTRQEQWLDFAHEVCHDFRHMNDDKIMPASWKRYLEYQANY
                     FAYHFCIPTFMLRAMDIPRNLYDAVQVIADAFKVPESFAMTRINMYFNKKRLII"
     CDS             complement(9199..9381)
                     /locus_tag="ctg8_906"
                     /transl_table=11
                     /translation="LKEKEFQSKPLLTKREREVFELLVQDKTTKEIASELFISEKTVRN
                     HISNGMHTGRKLRAL"
     CDS             complement(9497..9940)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_907"
                     /sec_met_domain="HBT (E-value: 6.1e-13, bitscore: 45.0,
                     seeds: 132, tool: rule-based-clusters)"
                     /sec_met_domain="HBT_2 (E-value: 1.6e-09, bitscore: 34.4,
                     seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLPVYIDMPFQEWKTSFSFFNEVSVRFSETDMFGHMNNVTPFIY
                     FEEARISYFKQLNMMSENKQTMTVVASQQCDYLRQVMPYEELRIYVKTSAVGSSSLTLH
                     YLGENLEGEPCFTGAVVMVQVSKESGKAVSWTDEEKETLLHTR"
     CDS             complement(10001..10762)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 96.2; E-value: 3.7e-30)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_908"
                     /sec_met_domain="Fer2_3 (E-value: 6.5e-29, bitscore: 96.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 2.3e-10, bitscore: 36.9,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.0044, bitscore: 13.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEQKTIRFIITRQDTADSTPYDEEFEIPYRPNLNVISALMEIRR
                     NPVNVKGEKTTPVTWDMNCLEEVCGACSMVINGKPRQSCTALIDQLEQPIRLKPMKTFP
                     VVRDLQVDRSRMFDSLKKVKAWIPIDGTYDLGPGPRMPEKRRQWAYELSKCMTCGVCLE
                     ACPNVNSKSKFMGPAPMSQVRLFNAHPTGAMNKSERLEALMDEGGLADCGNSQNCVQSC
                     PKGIPLTTSIAALNRDTNLQAFRNFFGSDRV"
     CDS             complement(10765..12525)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 296; E-value:
                     1.7e-90)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_909"
                     /sec_met_domain="FAD_binding_2 (E-value: 3e-89, bitscore:
                     296.0, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 8.6e-42,
                     bitscore: 138.2, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQSSIIVVGGGLAGLMATIKAAESGMAVKLFSIVPVKRSHSVCA
                     QGGINGAVNTKGEGDSPWEHFDDTVYGGDFLANQPPVKAMCEAAPSIIHLLDRMGVMFN
                     RTPEGLLDFRRFGGTQHHRTAYAGATTGQQLLYALDEQVRRYEVAGLVTKYEGWEFLGA
                     VLDDDRTCRGIVAQNLTNMQIESFRSDAVIMATGGPGIIFGKSTNSMINTGSAASIVYQ
                     QGAYYANGEFIQIHPTAIPGDDKLRLMSESARGEGGRVWTYKDGKPWYFLEEKYPAYGN
                     LVPRDIATREIFDVCVNQKLGINGENMVYLDLSHKDPKELDIKLGGIIEIYEKFMGDDP
                     RKLPMKIFPAVHYSMGGLWVDYDQMTNIPGLFAAGECDYSMHGGNRLGANSLLSAIYGG
                     MVAGPNAVKYVNGLESSAEDMSSSLFDAHVKKEEEKWADIMSMDGTENAYVLHKELGEW
                     MTANVTVVRHNDKLLKTDDKIQELMERFKKININDTTKWSNQGAMFTRQFSNMLQLARV
                     ITLGAYNRNESRGAHYKPDYPERNDDEWLKTTMAKHVSPYEAPEFEYQDVDVSLITPRK
                     RDYSKKKVAK"
     CDS             complement(12559..13167)
                     /locus_tag="ctg8_910"
                     /transl_table=11
                     /translation="MSGNREFYFRRLHSLLGVIPVGIFLIQHLVVNQFAARGAEAFNSA
                     AHFMDSLPFRYALEIFIIFLPLIYHAVYGVYIAFTAKNNAGQYSYMRNWLFVLQRVTGI
                     ITLIFVSWHVWETRIAAQMGAEVNFDMMANILSSPAMLGFYIVGVLSTIFHFSNGLWSF
                     AVTWGITVTPRSQRISTYVTLIIFVALSYVGLKAIFAFV"
     CDS             13460..13906
                     /locus_tag="ctg8_911"
                     /transl_table=11
                     /translation="MKSKFEASIDNLKEIEMNAYAYELIREIVLPDMLGQDYSSMMYWA
                     GKHLARKFPLESWEEFPAFFEEAGWGTLTNVSAKKQELEFELEGPIISNRLKHQKEPCF
                     QLEAGFIAEQIQLMNDQIAESYEQVKKRADKVVLTVKWDMKDPV"
     CDS             complement(13950..15176)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AA_kinase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_912"
                     /sec_met_domain="AA_kinase (E-value: 4.4e-53, bitscore:
                     176.4, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLIVQKFGGTSVGSVEKIQNAANRAIAEKQKGHQVVVVVSAMGK
                     STDELVSLAKAISDQPSKREMDMLLATGEQVTISLLSMALQVKGYDAVSYTGWQAGIRT
                     EAIHGNARITDIGTSVLADQLEKGKIVIVAGFQGMTEDCEITTLGRGGSDTTAVALAAA
                     LKADKCDIYTDVPGVFTTDPRYVKSARKLAGISYDEMLELANLGAGVLHPRAVEFAKNY
                     QVPLEVRSSTETEAGTLIEEESSMEQNLIVRGIAFEDQITRVTIYGLTSGLTTLSTIFT
                     TLAKRNINVDIIIQTQAEDKTGISFSVKTEDADQTVAVLEEYKDALEFEKIETESKLAK
                     VSIVGSGMVSNPGVAAEMFAVLAQKNILIKMVSTSEIKVSTVVSENDMVKAVESLHDAF
                     ELSKHPSAV"
     CDS             complement(15546..17318)
                     /locus_tag="ctg8_913"
                     /transl_table=11
                     /translation="MNKQLKEKLALLPDQPGCYLMKDRQQTVIYVGKAKVLKNRVRSYF
                     TGSHDAKTQRLVTEIEDFEYIVTSSNLEALILEMNLIKKHDPKYNVMLKDDKTYPFIKL
                     THERHPRLIVTRNVKKDKGRYFGPYPNVQAARETKKLLDRLYPLRKCSKLPDRVCLYYH
                     LGQCLAPCVKDISEETNRELVESITRFLRGGYNEVKKELEEKMHEAAENLEFERAKELR
                     DQIAHIESTMEKQKMTMNDLVDRDVFAYAYDKGWMCVQVFFIRQGKLIERDVSMFPLYQ
                     EADEEFLTFIGQFYSKNNHFLPKEILVPDSVDQSMIEQLLETNVHQPKKGPKKELLMLA
                     HKNAKIALKEKFSLIERDEERSIGAVQKLGEALNIYTPHRIEAFDNSNIQGTNPVSAMI
                     VFIDGKPYKKEYRKYKIKTVTGPDDYGSMREVVRRRYTRVLRENLPLPDLIIIDGGKGQ
                     INAARDVIENELGLDIPIAGLAKDEKHRTSNLLIGDPLEVVYLERNSQEFYLLQRIQDE
                     VHRFAISFHRQIRGKSAFQSVLDDIPGIGEKRKKMLLKHFGSVKKMKEASLEDIKKAGV
                     PTAAAQLLYDKLQK"
     CDS             complement(17454..17768)
                     /locus_tag="ctg8_914"
                     /transl_table=11
                     /translation="MAIVKATDQSFSAETSEGVVLADFWAPWCGPCKMIAPVLEELDQE
                     MGDKLKIVKIDVDENQETAGKYGVMSIPTLLVLKDGEVVETSVGFKPKEALQELVNKHL
                     "
     CDS             complement(18091..19578)
                     /locus_tag="ctg8_915"
                     /transl_table=11
                     /translation="MSEHQAVIQTDIVKGTINKNIYGHFAEHLGRGIYEGIWVGTDSDI
                     PNINGIRKDVLEALKQLHIPVLRWPGGCFADEYHWANGVGDRKTMLNTHWGGTIESNEF
                     GTHEFMMLCELLECEPYICGNVGSGTVQEMAEWIEYMTFEEGTPMSDWRKQNGREEPWK
                     LKYFGVGNENWGCGGNMHPEYYADLYRRFQTYVRNYSGNDIYKIAGGANVDDFNWTDVL
                     MKKAAGLMDGLSLHYYTIPGDFWKGKGSATEFTEDEWFITMKKAKYIDELIQKHGTIMD
                     RYDPEQRVGLIIDEWGTWFDPEPGTNPGFLYQQNTIRDALVAASHFHIFHQHCRRVQMA
                     NIAQTVNVLQAMILTEGERMLLTPTYHVFNMFKVHQDASLLATETMSADYEWNGETLPQ
                     ISISASKQAKGDINITICNIDHQNKAEAEIELRGLHKAADHSGVILTAEKMNAHNTFDD
                     PHHVKPESFRQYTLSKNKLKVKLPPMSVVLLTLRADS"
     CDS             19659..19871
                     /locus_tag="ctg8_916"
                     /transl_table=11
                     /translation="MNVSAFKVTILYMFVHVNDIFFIIYICTYVFTNIKTRTFKVRDFL
                     YECIFNCLNSSVNNGTTSNKSPTMP"
     CDS             complement(19793..20770)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ETF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ETF_alpha"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 154.1;
                     E-value: 1.2e-47)"
                     /gene_kind="electron_transport"
                     /locus_tag="ctg8_917"
                     /sec_met_domain="ETF (E-value: 2.2e-46, bitscore: 154.1,
                     seeds: 129, tool: rule-based-clusters)"
                     /sec_met_domain="ETF_alpha (E-value: 1.7e-36, bitscore:
                     120.2, seeds: 511, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKKVIVLGEIRDGELRNVTFEAIAAGRTISGDGEVIGVLIGENV
                     QSIAQELIHYGADKVLTAEDPKLKTYTADGYSQVMRGVIEQENPDSVIFGHTAMGKDLS
                     PKLAARLQTGLISDAIDVSVTGGNVVFTRPIYSGKAFERVISTDPMIFATIRPNNIQAS
                     EKDTSRSGSIESVNVSLTDLRTVIQEVVKKTADGVDLSEAKIIVAGGRGVKSMEGFQPL
                     QELAEVLGAAVGASRGACDADYCDYALQIGQTGKVVTPDLYIACGISGAIQHLAGMSNS
                     KVIVAINKDPEADIFKIADYGIVGDLFEVVPLLTEEFKQLNIHS"
     CDS             complement(20806..21579)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ETF"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 160.1;
                     E-value: 1.8e-49)"
                     /gene_kind="electron_transport"
                     /locus_tag="ctg8_918"
                     /sec_met_domain="ETF (E-value: 3.2e-48, bitscore: 160.1,
                     seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLFVLMKRTFDTEEKIVIETGKIQDDGAEWIINPYDEYAIEEAI
                     QLKEKHGGTITAVTVGGEEAEKELRTALAMGCDQAVLINIEDDLEEPDQYSISQVLYHY
                     MKDQEFDLILGGNVAIDGGSGQVAPRLAELLDIPCITTITKLEINGTDAEAERDVEGDV
                     EKIKTTLPLLVTAQQGLNEPRYPSLPGIMKAKKKPLEELELDDLDLDEEDAEPKLKTIE
                     RFLPPKKEAGKLLQGEPAEQAKELVSLLRSEAKVI"
     CDS             complement(21594..22370)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ECH_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_919"
                     /sec_met_domain="ECH_1 (E-value: 7.7e-65, bitscore: 214.7,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNAISLAVDQFVAVLTIHNPPANALSSRILEELSSCLDQCETDAG
                     VRSIIIHGEGRFFSAGADIKEFTSFKGNEDSSLLAERGQQLMERIESFPKPIIAAIHGA
                     ALGGGLELAMACHIRIAAEDAKLGLPELNLGIIPGFAGTQRLPKYVGTAKALELIGSGE
                     PISGKEALDLGLVSIGAKDEAEVIEKAKALAAKFAEKSPQTLASLLELLYSNKVYSYEG
                     SLKLEAKRFGEAFESEDAKEGIQAFLEKRKPQFKGE"
ORIGIN
        1 ttttcttttg ctggcgccgt tagtataatg gccggcagca ggatcaccgc tttaagcact
       61 gcgcatcagc tccatttgtc tgatcttttc ctcaagcacc ctaatagctg gtgtgagatc
      121 cttgccgccc ttttgttcag caggtccgaa caaatacatt cctttggatc ctataacgtt
      181 cgttttctcc ttcaatccca atcacccaat ctatggttta attccatcct gttgccctga
      241 atgatcactg tgtaatactt gcacatctga taaatccgtg accccagcgc ctcgtcaacg
      301 tccagcagat cgtccgttgt gagctcagaa gagatcagga gaggtttatg gttcaggtag
      361 cgataattca caactgactg gatctgttcg acttgccatt cggttgccct tggcttccca
      421 tcaactggct tgaataagtc atcaatgaac agcacatctg cttttctcat ggcattcagc
      481 tttgtttcca gctggtcaaa gtcattcttc agatcactca tgccctcaac gtaaggaaag
      541 tacaggcagt gagtcgattt cttcttaatg agattgttca tgatggccgt taacagatgg
      601 gttttgccgc tacccggctg tcccagcaga gcaatgctat tggcacgctc tcccttgatc
      661 ttttcaaagt ctttgaagta ttcgaccgca cattcatagg catctttaat catttggggt
      721 ttgccatcta atttgaagtt gccaaacaac agcttttcga acttttctgt aatgccgctg
      781 gctgccatga gcttcgctat tttcttttgt ttcacacact cacattgttt tgaatacgtc
      841 gttttccatt cccgagcctt atccggcgtg caaacctttc ctgcaaggta atcatcttca
      901 agaaccattt catcaagtga taggctgtcc aatggcttgt gttcttttct caaccgcagc
      961 tcagtgtctt tgtggatgcg gtagatcaca acgccgcgat ccttgcactc ggaacactca
     1021 tactcaacct tttcttctga tgcggcctgt tctgtttccc aggaacgcga tcttgcttga
     1081 agacccttca tcattgcttg gaacgctgtg tctatactga ctgctttgtt tattgccata
     1141 ctgttgtttc tcctttctct tttggctgaa cgggtttgac aggatcgcct caatgtagct
     1201 caggccaaca ttgctgcctt tatttctgaa agcctttttc atggcctcca tgaccttctc
     1261 ttcgccgtaa tcatccacca tgtagccgat tctttgcgcc tcaatggagc cgatagaacg
     1321 agcgacctta ttttcgaata gctcaaaagc gtttttcatt tttggatcaa cctcctgcgt
     1381 ttcttgtggt gctggtgcaa gttcaggaac aggcttttct gatggttcct gctctgatac
     1441 aggagtttca aatgagatca gcctgtattg ccctgccttt ctcccctgcg gcttatattc
     1501 gattctttta agatcaatca gcatctttct gtgtttgatc aacgtatttt cggaaatctc
     1561 aatctttgct tgcagagtgg tatttgaagt ggtgaaccac tcccgccacc ctgccttgtt
     1621 gttgatgtgc aaaagatgaa accataatgc ttgagttgta gcagacaacg gattcgtttc
     1681 tagccaattc atgaagccgt tcatttcttt caggtagttc atggctcacc tacttccttt
     1741 cacacagtgc tgtcattccg ctgatgcgga ctaaacgtaa gccaggttca tttgttctga
     1801 gatagccttc aacgtaagca cggaacagct gcgcgcgatt gggtgcccct tctgccagcc
     1861 acttataaca gaaggggata ctaaccttaa tcaaatggga ggtcatcgtc gctgatgtct
     1921 acaggcttgc cgtcaaaagg atcagcatcc tgcgcgcttg gtttttcctc agatggttcg
     1981 gcatcaatga tttctggctc agacatttcg tcagtaatgt caattcgctc gcgttcctcg
     2041 ttatcctcaa tgactgcctt ttgcatttca acggagagaa tcccccactt gctgagcatg
     2101 gattttagaa cggttttgag tgccatcgca tcccagtcct tgccccaacc gaagtccgac
     2161 ttactaaatt tctttttgtg tttctcaact tgcgcctttg tccaatagac agtttttcgg
     2221 aatccattta aaagttcgaa ataagcagca taaccaataa ccgactccga ttcccgcttt
     2281 gcaaaatcaa tatcaatttc ctcggtcaac ggattccact tttgcaattc tccttcatga
     2341 accggtatgc aattgataga tttatattgg cccgtccgca aagcaagctg aatgtatcct
     2401 ttgtaaccaa gctgaaattg cgcacggcct ttatacggaa cgatccaggc ataacctaag
     2461 ttcttatcca ctggcaaatc gagcgttgcc gccaccatag ccgatgaaat tacactcata
     2521 gggtctgcct tttgaagcgt attttcactg ttgtacaggc tcagaattga cgctgtgaat
     2581 tgagacgctc tttttcccag aacttcttcg aatcgattca tgactgccgg agaagaaagt
     2641 aggcccttca tcgttgttcc ctgctgttgt cctggggcac tgttttgttt cttctgaatg
     2701 ctgtttttaa gcgtttgatt tgtagccata ttcagctaac ctccttaatt ccaaagcgcc
     2761 tgaattgcac ttcttttgtg actttctcgt atacatctgg aaactgctct ttcaatttct
     2821 tgctatcgat ccgattagtt gaaactgact tccagctagt ttgatagttt ccgatgaatc
     2881 catattctgc ttccttcatt tcatgtttga tctggttttc taattccttt gcctgcaatg
     2941 acagctcgtt gatctgctct ttcagctgta aatactgctg aatacgtgtt ttattatcag
     3001 atgtgagatc aacgactttg ccgccttctg cttcggcata acgttgcttg agatattctt
     3061 ctgcagcact cgaaccgtca agaaccggag cctttccgcc caagaccttt tcattccaaa
     3121 attcaatttc ggcctgaaag atcattgcaa taagctcgtc atcgcgctca atctctttcc
     3181 aaacgaattt attgccgccg atcagtacag caaaatatgc ttttttatat tcaggcccta
     3241 gcactcctag atagtgttgg acctgaacaa tatagctatc aggaatttcg tcatcttccc
     3301 actctttaag gttgtatgcc gatgtggttt tgcactccaa tatggctttt tcaccaacaa
     3361 tcattcggtc aacattcgcc aatataaaat cgtgcttagg gtgcctgagc attgcttttc
     3421 tccgccttac tttttttccg ctacgtatct caaactcttt tgcaacgata tcttcaagaa
     3481 gtgaaccgaa gtaggctgcc tcacttcctg attcactcac aggcacttga cctgttttgt
     3541 ctaaccataa ttcaaacggt gtttgccatt tgtttatgcc taaaattaca gaagcatctg
     3601 aaccgccgat gcctttccgt cgctcaagaa gccattcgtc ccgactcatg tccgctgtcg
     3661 aagcgaaaac ctctgcttgc atcagagcag ccccaccttt cttttgtaag cttccgcacc
     3721 aagccgctgc cattcccggt agtgatccat tgaagggaaa ctaaactgcg ctttaccatt
     3781 tttggcgaat acaattgaac cgccgacctg tcttaaacgt tgctgatcct ccgcacgctc
     3841 gctgaacgcc actttaactg ctttagccat gtataaaacc cccattgatt ttcttgaggc
     3901 tatctggtaa actattggta catgagtttt cagatagctt ttatttgagt ccacttgcca
     3961 agtgggcttt tttattgctc atttttaaat ttgaagccaa gctgttgctt taagtaacga
     4021 tcaagattct ctctcaaaat caaagtgccg cagtcaatca catagtcatc aactggtgtt
     4081 acttcatccc cgaaaaaatc ctttggtgtt tctggctcag tcagcctatc gtgccagttg
     4141 tttagaatca ttggattctc gatcattcat attctccttt ctgtaatttg ctgtacgttc
     4201 atcccaaatc aggtgcagtt ctctatgatt tcggattctt tcacaccacg ctcggacctc
     4261 caacgctgtc gctggtttat gaacaaagtg aaccatcatc ctaagctcct gcgtaccact
     4321 gataaatcaa tcccacgctg tttcagcctt atcgctgcat catataagcg tcccttattt
     4381 gaaatccgtt taagatcctc aatgtttgct ttgatactgc caaggatgtc taaagcttcc
     4441 tcgtagtcgc cttcttccaa agagtccagt aatagttcag ccaaactttc aactgaatca
     4501 gttttccgtt ttacgacttc ttcatctgac ttcaaaaatt ggttgagttt catacgagca
     4561 ttgccttcct ttcctcttgt tttgacatag caacctgatc cattaacgct tttcgcgtcc
     4621 atttgtctgc aagctcctgc attttcagac catgacttcg agataaagca taaaagagag
     4681 tgtctacagc tggaccaagg tcaagaatct ctttaagatc cgccatcggt agcgcctcaa
     4741 tacggccggg gcgttcattc gccaaccaga gcgcgatatt ttcagcagcc tcaagggatt
     4801 cctttgtctg tttcataaaa ttgatcaggg ctttactggg gctgacgttc aacgccggat
     4861 cgactggggc tgttgccctc ggatgaagcc ggaacaaata atgtacaagg tcaatgtgct
     4921 cataagcgcc gcatatctca aaccatttga tgcaaagttc aggcgttagt gtggtcaggc
     4981 cattttcaac gtctgataca taccgttgat ctttgccgcc aagtaactgc cctaattgaa
     5041 attgagtaaa tcccattgtc tttctaacct ctctcataat ttttggtaaa ttatcgagtt
     5101 tatacgggtt gttcgacata tgttcgcctc ctgtttcacg gggaattatt tggtaaaatt
     5161 taagtaatga aggaactagc tggcttgctg ttttttcagc ttattgatga tgaaggcttg
     5221 tcccttcgga gtgatgcgca ttgtcagcca ggatttcggc gtcccgttta cttggcgcac
     5281 cccctgtgcg atctcaaaga aacctcgctc gatgtattcc tggtatggct cattcttgtt
     5341 ggccatgatc atcttccatt cgcgcagctt ctgaaacagt cgcttttcac caatcatgat
     5401 gccgtttttc gaagcaagct ttgccagttc tctcacaagc aatgattttt cggccgccat
     5461 gcaactctgt gcaaagttga ccaatggttc ctgaatcttc aatgcttgtt caagttgctg
     5521 ccgttcttcc tgctcgctga tccatcgctt tgcccggctg actggatctt cgatcatgta
     5581 ggacggttga gtcatttttt gaagttcggc ttccatccgg ttaaattcgg caatgtattt
     5641 ttctttgaac actgctgctt tggcgcccgt gtaaccaaaa accagaaatg tgagtccatc
     5701 gcgtttaatc agatattttt tcaatgatcg gcctgttgga tctagatatt cactcaacga
     5761 aaaatttcgt tcagcaaaat ctttagagca attaagcgtt tcaatgcttt ttattacatc
     5821 ggcgtgacgt tttccgaata cctcagccac tgtcaggctg tctgttacgg cttggttgcc
     5881 ttcaataaaa acaatttgat tcatgctgtt acctccttgc ttgtccacca aaaaaaggtg
     5941 aagcagaata ttaagcgtga agccttaatt cttttttaga agtgaagtac ggctcaagag
     6001 ctttacggaa acactcttct ctgtccatcg ttccgtaata ttctttgccc atcttgatgt
     6061 ttgttgtttt tttcttagtt tgtttcgcca tgtgatcacc tcacgtcagt gtattcgtgt
     6121 tggacggttg gactaaccaa gaattttgct tactttgtaa tctatcaacc tttcacttgt
     6181 ggtaaaatct tctacgtgaa aggtggggag aatatatgga ttttaagaaa atcagtgaca
     6241 atgcttatct tgaatggttt acagaacacg ctggtaatct cagcatgtac ggtaaggaag
     6301 acttaccgga attcatgaaa gatgaaaaag atgttcactt atttcttcaa aaattcgctc
     6361 aagatatcag cttactaact gtcaaaagct atcattctga gcttgctaag aaactgaagg
     6421 aatacgacat cgaccttgaa tccttagaaa ttccaaacaa gaaataagac aaaattcaac
     6481 ttggccggga ctggattttt caatgaagtt ggcggcttca ttgatggtcc agttcgtggc
     6541 tgaagcaatt acttttgctt tgttcatttg aatctaactc cttttattgg ttcatattaa
     6601 gaaattctaa attcacgttt taagttaatt tctaatagtt ctgagtcgtc aaactgcact
     6661 ttggcgactt tagaactgaa caacatatct acatgttgtt tgatccgatt ccattcagac
     6721 tgagacatac cattcaacaa atcgtttaat tgatctatct tcttttgatt catgttttca
     6781 ctcctatgct gtgtgtgttt ttaaattaca cgtaatgtga cattcatcct caaaaaaata
     6841 tgtccaatcg aaatcaagaa cacccgcaat gcttttagca acttgtggcg tcggattcct
     6901 agatcctgat tcaatcattg catatgttgt tcgtgcaatt tttgcttctt ccgcgacttg
     6961 tttttgagtc attttgtgtt cttgtctaag tttttctagc cattgacgtt tttgtttaat
     7021 atacatttcc tcacctccat gtcacgtatc gtgtaaccat ataataatac acatatcgtg
     7081 acttgtaaag agaaaattac acaatttgcg aaattagtgt attgtcacaa attgtgacgt
     7141 tataataatc aggaaaggag cgtttattat gcttggtatg cgattaaaaa aactccgtaa
     7201 gtcaaaaagc ttagaactaa ataaagaaat taagcaagaa gaagtggcaa aaaatatagg
     7261 agttggcaga accacttatg cgatgtatga gcaggataag cgccagcctg attatgaaac
     7321 tttaattaaa cttgctgatt attatgaagt cacaactgat tttctcttaa gaggagaaag
     7381 tcaggaggct aaagataaaa tcttcaacga agaagcaaga aggattcttg aagatccaga
     7441 tactctggta gctgctgctg atggaaaaat aacagcttca attttagaag cagctcaacg
     7501 aattattgct gagcaattaa aatcaggaag acaacccgga gatataaaaa acgggaacaa
     7561 aaaataatta cataacgatc tctttatctt tatttattat tattgtttag tttagtttaa
     7621 ttaatgctga acacatcgcc tcaaaatttg aggtaaacta ttcagttgaa atcatttcaa
     7681 cctcaatttt tgaggtgatc catgaggtta tttctgcatt caaccgcaaa ttttgaggta
     7741 aaacattcag ggtttataaa tcagtcatca gagagaaaaa gtaaaaaaac ccttaattta
     7801 gtcgataaaa agagagagat ttcacttcac tataaaaggg gaaattacaa ttgaaaaaat
     7861 ggttattagg tattggagca ttgactctca gtttttcttt agctgcatgt aattcggagg
     7921 attcctctgc aaaagacaat aaagccaaag aggaaaaaac agcaacaaaa actgaagaaa
     7981 aaacagaaga taagacaaca gccaaaaaag actcttcaac tgattcttca gcagaggaaa
     8041 aatacaagtt ctctaatgaa tccggtgact ttacaatgtt agccggctat acaaatgatc
     8101 aaagtgataa agcgcaaggt ttcattacct tagacttcca aggtttcaca ctcaagttta
     8161 tgcctgttct tgtagacctt aaattgtctg attccatgaa gcaagaagaa gaattcagtg
     8221 gaaaagatac aatcagagca attatgatct caacagaggc tgagaacact gctgatcacg
     8281 atgtagatta taacggtgat attacggtaa ttacagatac aaaagaacag cttacagctg
     8341 atagtgggct actgtctaac aatcctattg ttaaaaccta tcaaggaaaa gtcaaagagg
     8401 aaggctattt cttgattccg ttaaaagatc agaaatctac tcctaaagag cttgagctta
     8461 gattcacgcc gccatataaa gtagaaaacg gtgctgttaa caccgaaaca ggtttaatgg
     8521 gtaaagaaca aacagtaaaa gtcaaatata cttctagaga atcattataa aagaatgccc
     8581 tcatagtggg gcttttcttt tcgctaaaaa gagaacatac gtttgttcat cttcaaccaa
     8641 ataggtgata agatacaata aagcccatga taaaagtcac atctttggtt atttaaggga
     8701 ggtttcatct ttgagataca ctaacagcca tttagaagat tggattgaac agttgtacaa
     8761 agacatcaac attttaaagc cgcatgagat taattttgat aggattgctc aggccttgga
     8821 catcttaatt gtttacaatc cggaaacgag ttttgctctg cgattcaacg gcatgtatac
     8881 aatttcttta gattcacgaa agacacgaca ggaacagtgg ctggattttg ctcatgaggt
     8941 ttgccatgat tttagacaca tgaacgatga taagatcatg cctgcttcgt ggaaacgata
     9001 tttagagtac caggccaatt attttgcgta tcacttttgt atacctactt tcatgctccg
     9061 agcaatggac atcccccgta atctatacga cgcagttcaa gtcattgccg atgccttcaa
     9121 ggttccagag tcatttgcga tgacccgcat caatatgtac ttcaataaaa aacgactcat
     9181 catataaaaa aagagcctct aaagggctct tagtttgcga ccggtatgca taccatttga
     9241 aatatggttt cgaacggttt tctcactgat aaatagctcg cttgcaatct cctttgttgt
     9301 cttatcttga acgagcaatt cgaacacttc tctttctctt ttcgttagca gcggcttcga
     9361 ttgaaattct ttctccttca agtattgtaa ccctccttgc taaggtgaga gcgaatcaga
     9421 aacgaatggg ttttgatata gtcgagatat catatgtaag aagggcgcag gaggtgacgt
     9481 ttacaagata attagtttat cgtgtatgaa gaagcgtttc tttctcctca tccgtccagc
     9541 tgacagcctt gccgctttcc tttgagactt gaaccatcac gactgccccg gtgaagcagg
     9601 gttcgccttc gaggttctct ccgagatagt gcaaggtaag agatgaactg ccgactgcgc
     9661 ttgttttcac atagatgcgc aactcttcat aaggcatgac ttggcgcaaa taatcgcatt
     9721 gctggcttgc cacgacggtc atggtctgtt tgttttcact catcatattc agctgtttaa
     9781 aataagaaat ccgcgcctcc tcaaaatata taaaaggggt tacattattc atatgcccaa
     9841 acatgtctgt ctcggaaaat cttacggata cctcattgaa aaaagaaaag gatgttttcc
     9901 attcttgaaa cggcatatca atataaacgg gaagcttcat cttttttcat ctccttattg
     9961 tttaaaaaaa cctctcccat gcggaagagg ttttttcttc ttatactctg tcgcttccga
    10021 agaaattgcg gaacgcttgt aagtttgtat ctctattcaa ggctgcaatc gaagtggtaa
    10081 gcggaatccc cttcggacag gattgaacac agttttgcga gttgccgcaa tctgcaaggc
    10141 cgccttcatc cattaatgct tctaatcgtt cagatttatt catggcgcct gtcggatgcg
    10201 cgttaaacag gcgaacttgc gacatcggtg caggccccat gaacttcgat ttgctgttca
    10261 cattcgggca agcttcgagg cagacgccgc atgtcatgca ttttgataat tcatatgccc
    10321 attgacggcg tttttctggc attctcggcc ccggtcctaa atcgtacgta ccgtcaatcg
    10381 gtatccatgc tttaactttt ttcaatgaat caaacattct gctgcgatca acctgcaaat
    10441 cacgaacgac tgggaatgtt ttcattggtt ttaaacggat tggctgttca agctggtcaa
    10501 taagcgccgt acaagactgg cggggttttc cgtttataac cattgaacat gcgccgcata
    10561 cttcctcaag acagttcata tcccatgtga caggggttgt cttctcacct ttgacattaa
    10621 ccggattccg gcggatttcc atcagagcgg aaatgacgtt cagattcggg cggtatggaa
    10681 tctcaaattc ttcatcgtaa ggcgtgctgt cggctgtatc ttgacgtgtg ataataaatc
    10741 gtatggtttt ttgttcactc atgattattt cgccaccttc ttcttcgagt aatcccgttt
    10801 ccgaggcgtt atcagtgata catcgacatc ctgatactca aattccggcg cttcatacgg
    10861 gcttacatgt ttagccattg ttgttttgag ccattcatca tcattacgtt caggataatc
    10921 cggtttataa tgggcgcccc ggctttcatt acggttgtat gcgccaaggg taatcaccct
    10981 agcaagctga agcatgtttg agaactggcg tgtgaacatc gctccctggt tgctccattt
    11041 tgtcgtatca ttgatgttga tctttttgaa gcgctccatt aactcctgaa ttttgtcatc
    11101 cgttttcaaa agcttgtcat tatggcggac aaccgttacg ttcgccgtca tccactcacc
    11161 gagctctttg tgaagaacat aggcattttc ggttccgtcc atactcataa tatcagccca
    11221 tttttcttct tctttcttaa cgtgagcgtc gaataaagat gaagacatgt cttccgctga
    11281 agattctaag ccgtttacat atttcaccgc attcggaccg gccaccatgc ctccgtaaat
    11341 cgcagacagc agggagttcg ctcccaagcg gttgccgccg tgcatagaat aatcacattc
    11401 cccagccgca aacagtccag ggatatttgt catttgatcg taatccaccc ataaaccgcc
    11461 catagaataa tggaccgccg ggaagatttt cattgggagc ttacgcgggt cgtctcccat
    11521 gaatttctca taaatctcaa tgatgccgcc aagcttaata tcaagctctt tcggatcttt
    11581 atgagacaga tcgagatata ccatgttttc accgttaatg ccgagcttct ggttcacaca
    11641 cacatcaaat atttcgcgtg tcgcaatatc acgcggcacc aggtttccgt atgccggata
    11701 tttttcctcc aggaaatacc atggtttgcc gtctttatat gtccacacgc gcccgccttc
    11761 accacgcgct gattcactca tcagtcttag tttgtcatcg cccggtatgg ctgtcgggtg
    11821 gatttgaatg aattctccgt ttgcataata cgctccctgc tgataaacga ttgatgcagc
    11881 agatcctgta ttaatcatgg agttcgttga ttttccaaag atgattcccg gtccgcccgt
    11941 cgccataatg acagcgtctg aacggaagga ttcaatttgc atgtttgtca ggttttgagc
    12001 aacaattccg cggcaggttc tgtcatcatc taaaacagcg ccaaggaatt cccagccttc
    12061 gtattttgtg accagacccg caacttcgta tctgcgcact tgctcgtcca gtgcgtaaag
    12121 cagctgctgt cccgtcgtcg caccagcata agcagttctg tggtgctgtg tacccccgaa
    12181 tcggcggaaa tcaagcaggc cttcaggcgt ccggttaaac atgacgccca tccggtctaa
    12241 taagtggatg atcgaaggcg ccgcttcaca catcgccttg accggcggct ggttggcaag
    12301 aaagtctccc ccgtataccg tgtcatcaaa atgttcccac ggagagtcac cttccccttt
    12361 tgtattgacc gctccgttta tgccgccttg cgcacaaacc gaatgagaac gtttgacagg
    12421 aacgatggaa aacaacttaa ccgccattcc tgattccgct gctttaattg tcgccatgag
    12481 gccggcaaga cccccgccga ctacgataat gcttgattga ctcatgatag cccctctccc
    12541 tctagtaatc tagtactctt aaacaaatgc gaaaatcgct tttaagccta cgtatgacag
    12601 tgcaacaaaa ataatcagcg taacgtatgt cgaaattctt tgagaacgag gcgttaccgt
    12661 gatgccccat gtaacagcga aagaccataa accgttcgag aagtggaaaa ttgttgataa
    12721 aacaccgaca atgtaaaaac caagcatagc cggagagctc aaaatattcg ccatcatgtc
    12781 gaaattgacc tcagcaccca tttgtgcggc aatgcgggtt tcccacacgt gccagctgac
    12841 gaaaatgagg gtgatgatac cggttacacg ctgcaggacg aatagccagt ttctcatgta
    12901 gctgtattgg cctgcgttat ttttcgcagt aaacgctatg tacacaccat aaactgcatg
    12961 ataaattaat ggtaagaaga taatgaaaat ttccaaggca tacctgaaag gcaggctatc
    13021 cataaaatga gcagcgctat tgaatgcttc agcgcccctt gcggcaaact ggttgacgac
    13081 taaatgctga ataagaaaga tgccgaccgg tatgacgcca agcaaggaat gcaatcttcg
    13141 aaaataaaac tctctgttcc cagacattac tttaccccct gtttgataag tgcgaaatgt
    13201 gctaaatctc ttcccccact tctttcaatt gtaagcactt tattaagatt tattgacaat
    13261 ttcattttac tcctccctca aaagggcgtc aagaaaacgc gtacataaat tataattttc
    13321 cgaattgatt agttgattga aaaattttat tttatcaata tatatttctt gcttaatttt
    13381 tcataagaat tacaggatca ttctgtaatc ctcccccctg tttaagctat aatatacgca
    13441 ggagagaggg gagacagata tgaagtctaa atttgaagca tctattgaca acctaaaaga
    13501 aattgaaatg aacgcctatg cctacgaact aatacgagag atcgttctcc cagatatgct
    13561 tggccaagat tactcttcca tgatgtattg ggcaggaaaa catctcgccc gtaagtttcc
    13621 tcttgaatca tgggaggaat ttccggcctt ctttgaagaa gcgggctggg gaaccctcac
    13681 caacgtaagc gctaaaaaac aggagcttga atttgaactt gaagggccga tcatttccaa
    13741 ccggcttaaa catcagaaag aaccttgctt tcagctggag gctggtttta tcgctgaaca
    13801 aattcaattg atgaatgatc agattgccga atcatatgaa caagtgaaaa agagagccga
    13861 taaagtggtt ctgactgtga aatgggatat gaaagaccca gtgtaatcaa aaaggcggtg
    13921 actgcatagt cccgcctttt tgattgtcat tacacagctg aagggtgttt tgaaagctca
    13981 aatgcatcgt gaagcgactc gactgctttc accatgtcat tttcgcttac gactgttgac
    14041 actttgattt cagaagtgct gaccattttg attaaaatgt ttttttgcgc tagtacagca
    14101 aacatttcag ccgctacacc aggatttgag accatgccgg atccaacaat ggatacttta
    14161 gccaatttgc tttctgtctc gattttctca aattccagcg cgtctttata ctcttcaagc
    14221 accgcaacgg tttggtctgc atcttctgtt ttgacagaga aggaaattcc agtcttgtcc
    14281 tcggcctgcg tttggataat gatatccacg tttatgtttc ttttggcaag tgtcgtaaaa
    14341 atagtagaca aagttgtcag gccgctagtc agcccgtaaa tggttactct tgtgatttga
    14401 tcttcaaatg caatgcctct gacaattaaa ttctgttcca tggatgattc ctcctcaatt
    14461 aatgttcccg cttcggtttc tgtacttgaa cgcacttcta acggcacttg gtaatttttc
    14521 gcgaactcaa ctgctcttgg atgaagaacg ccggcgccta aattggcaag ctcaagcatt
    14581 tcatcgtatg agatgcccgc aagttttctc gctgatttca catagcgcgg atcggttgta
    14641 aacacgcctg gcacgtctgt gtatatgtca catttatcag cttttaaagc ggcagccaaa
    14701 gcaactgctg ttgtatctga accgccccgg cccaatgtcg taatttcaca atcctctgtc
    14761 atgccttgga atcctgcaac aatgacaatt tttccttttt caagctggtc tgctaaaacc
    14821 gaagtgccga tatctgtaat tctggcgttt ccgtgaatgg cctccgtacg gattcccgcc
    14881 tgccagccag tataagacac agcgtcatag ccttttacct gcaatgccat tgaaaggagt
    14941 gaaatcgtga cctgctcgcc tgtcgccagc agcatatcca tttcgcgttt gctcggctgg
    15001 tcagaaatag cttttgcaag gctgaccaat tcgtcagtgg attttcccat tgctgaaacg
    15061 acgacaacga cttgatggcc tttctgtttt tctgcaattg cgcggtttgc cgcattttga
    15121 attttttcga ctgagccgac ggaagtgcct ccgaattttt gtacaataag acccatgtat
    15181 taccaccctt tatattttgg ttcgtgcggg tgaggagaaa gagcgctttg tccacaataa
    15241 aaaaagcaat gagaggaata ctctcattgc ttatcaatta atcatcataa atgattatga
    15301 acaacgagat agccctccaa gaaaatgatt tcttgacagc cttacattta ttcaatgcac
    15361 agccagcaaa taataccgat ggggttttac ttgcttcggc gacgctcccc tttcagcctt
    15421 tttcacagaa tccatctttc tccaaaggca tactcttgaa gttcgcacct ctatcttcac
    15481 catataacac gatctaacta tgaaattagt tcacatttta tcagatctta tttaaaagga
    15541 caacattatt tttgcaattt gtcgtaaagg agctgagccg ccgctgtggg aacaccggct
    15601 tttttgatgt cctcaaggct tgcttccttc atttttttaa cggaaccgaa atgctttaac
    15661 agcattttct ttcttttctc tccgataccc gggatgtcgt ccaaaacgga ttgaaacgcg
    15721 ctttttccgc ggatttgcct gtgaaaactg attgcaaaac ggtgcacctc gtcctgaatg
    15781 cgctgcagga ggtaaaattc ctggctgttt cgttccagat acaccacctc cagcggatca
    15841 ccgatcagta aatttgaggt tctgtgtttt tcatctttcg ctaaaccggc gatcgggata
    15901 tccaagccga gttcattttc aatgacatcc cttgctgcgt tgatctgccc ttttcctccg
    15961 tcaatgatga tcagatcggg cagcggcaga ttctcacgaa gcactctcgt atagcgtctt
    16021 ctgacaacct ctctcataga accgtaatca tccggccctg taacggtttt gattttatat
    16081 ttgcggtatt cctttttgta tggtttgccg tcgataaaca caatcatcgc ggaaaccggg
    16141 tttgtcccct gtatgtttga gttatcaaac gcttcaattc tgtgcggcgt ataaatattt
    16201 aatgcctcac ctagtttctg cacagccccg attgaacgct cctcgtcccg ttcgattaaa
    16261 gagaattttt ctttcaatgc gattttcgca tttttatggg ccagcatgag cagttctttt
    16321 ttcgggcctt tcttcggctg gtgaacgttt gtttccagca gctgctcgat catggattga
    16381 tctacgctgt ctggaactaa aatctccttc ggaaggaagt ggttgttttt tgaatagaac
    16441 tgcccgatga acgtgaggaa ctcttcatct gcttcctgat aaagcgggaa catgctgaca
    16501 tcgcgttcaa tgagcttccc ttggcggatg aaaaagacct gcacgcacat ccagccctta
    16561 tcgtacgcgt acgcgaatac atcacggtcg actagatcgt tcatcgtcat tttttgtttt
    16621 tccatcgttg attcaatatg ggcaatttgg tcacgaagct cttttgctcg ttcaaactca
    16681 agattctcag cagcttcatg cattttctct tcaagctctt ttttgacctc attatagccg
    16741 ccccttaaga aacgtgtaat gctttcaacc agctctctgt tcgtctcttc ggaaatatcc
    16801 tttacgcacg gagcaagaca ttggcccaga tgataataaa ggcacactct gtccgggagc
    16861 ttggagcatt ttctgagagg atacagacgg tcgagcagtt tttttgtttc ccttgctgcc
    16921 tgtacattcg gatacggccc gaaatagcgc cctttgtctt ttttgacatt gcgggtgaca
    16981 atcagccttg ggtggcgttc atgggtgagt tttatgaaag gataggtttt gtcgtctttg
    17041 agcatgacgt tgtatttcgg atcatgcttt ttgatcagat tcatttctaa aataagcgct
    17101 tcaagattgg aggacgtcac gatatattca aaatcctcga tttccgtcac aagcctttgg
    17161 gttttcgcgt cgtgagaacc ggtgaagtag gagcgcactc tgtttttaag cacttttgct
    17221 ttccctacgt agatcacagt ctgctgccgg tccttcatga gataacaacc cggttgatcg
    17281 ggaaggaggg cgagtttttc tttcagttgt ttgttcatat gttacccttc cttatgttta
    17341 atcctttatt tccagtttaa cacgaacgtt tgtttttctc tatggttcac aattggcgaa
    17401 taaaaaaagc gatccctcaa tcggaatcgc tctggcatgt aagcagcgga aaattaaaga
    17461 tgtttgttta caagctcttg aagcgcttct tttggtttga agccgactga agtttcaact
    17521 acttcgccgt cttttaacac aagaagagtc gggatgctca taacgccgta ttttccggca
    17581 gtttcttggt tttcgtctac atcgattttt acgattttca gtttgtctcc catttcttga
    17641 tccaattctt caagaacagg tgcaatcatt ttacaaggtc cgcaccaagg agcccagaag
    17701 tctgccagta cgacgccttc gcttgtttca gctgagaaag attgatcagt tgcttttacg
    17761 atagccatta ttgaattcct ccaatgtgaa atgatgattt ttagtatagc atctcccatt
    17821 cgttcacgct attttaatgc ttacaaatta ttttttcctg atcacagccg gtttactcat
    17881 ttttatatgg ttgaatggga tatgctcttt ttttaaaaca caaatctgat aatggccccg
    17941 atcactacaa ttgccccaat aatcattaaa atggtacgaa gcataagatc acatctcctc
    18001 ttcactgtca tgtactttac catgccctgc cggagctgtt ttaaaacctg aaaaagagcg
    18061 ccggcatgaa gctccggcgc tcttgcgcga ttaagaatca gcacgcagcg taagtaagac
    18121 gactgacatt ggcgggagtt ttactttcag tttgtttttg ctgagcgtgt attgcctgaa
    18181 ggattccggt ttgacatgat gaggatcgtc aaacgtgtta tgcgcattca ttttttctgc
    18241 cgtaagaatg actccggaat ggtccgctgc cttgtgtagg cctctcagct cgatttccgc
    18301 ctccgctttg ttttggtgat cgatgttgca aattgtgata ttgatatcac ctttagcttg
    18361 tttcgacgct gaaatgctga tttgcggaag cgtttcaccg ttccattcat agtcggcaga
    18421 cattgtctct gtggctaaaa gagaagcgtc ctgatgcacc ttaaacatat tgaatacatg
    18481 gtacgtcggt gtcaaaagca tccgctctcc ctcagtcaaa atcatcgctt gcagaacgtt
    18541 tactgtttgg gcgatgttgg ccatttgcac ccggcggcaa tgctgatgga aaatgtggaa
    18601 atgagaagcc gccaccagtg catcacgaat ggtgttttgc tgatataaaa aaccgggatt
    18661 cgtgcctggc tcgggatcaa accacgtgcc ccattcatca ataatcagcc cgacccgctg
    18721 ctccggatcg taccggtcca taatcgtgcc gtgtttttga atcaattcat cgatgtattt
    18781 ggcttttttc atcgtaataa accattcatc ttccgtgaat tctgtggctg atcctttgcc
    18841 cttccagaaa tcccccggaa tcgtgtaata atgaagactc aacccgtcca tcaggccagc
    18901 ggcttttttc ataagcacgt ccgtccaatt aaaatcatcc acatttgcgc cgcctgcaat
    18961 tttataaatg tcattcccgc tgtaattgcg gacataagtc tgaaaacgcc ggtacagatc
    19021 tgcgtagtat tcgggatgca tgttgccgcc gcagccccag ttttcattgc ccacgccgaa
    19081 atatttcagc ttccaaggtt cttctcttcc attttgcttt ctccagtctg acatcggcgt
    19141 gccttcttca aatgtcatat actcaatcca ctccgccatt tcctgaacgg ttccgcttcc
    19201 gacattgccg caaatatatg gctcgcattc aagcagctcg caaagcatca taaattcatg
    19261 cgttccgaat tcatttgatt caattgtacc gccccagtga gtgttcagca ttgtcttacg
    19321 gtcaccgaca ccgtttgccc aatggtattc gtccgcaaaa cacccgcccg gccacctgag
    19381 gacaggaatg tgcagctgtt tgagcgcctc cagcacgtcc tttcgtatcc cgttgatatt
    19441 ggggatgtct gagtccgttc cgacccagat cccctcataa atccctcttc ctaaatgctc
    19501 agcaaaatga ccgtatatat ttttgttaat ggttcctttt acgatatctg tttgaattac
    19561 tgcttgatgt tcagacatgc ctctgatcat tcctttcata cggatatgaa aagcaccaca
    19621 gtcaaatatg tgatctgtct tttgcctgag gagtcagcat gaatgtaagc gcttttaaag
    19681 taaccatatt atatatgttc gtacatgtca atgatatttt ctttatcatt tatatttgta
    19741 cgtatgtatt tacaaatata aaaacccgga cttttaaagt ccgggatttc ctttatgagt
    19801 gtatattcaa ctgtttgaat tcctcagtta ataacgggac aacttcaaat aaatcaccga
    19861 cgatgccgta atccgctatt ttaaagatat cggcttcggg gtctttattg atggcgacga
    19921 tcactttgct gtttgacatg ccggccaaat gctggatggc gccggaaatg ccgcatgcaa
    19981 tgtacaaatc cggagtaacg actttccccg tctgcccgat ttggagagca taatcgcaat
    20041 aatcagcgtc acatgccccg cgagaagccc cgactgcggc ccctagcacc tctgcaagct
    20101 cctgcagagg ctgaaatcct tccatgcttt tgactcctcg gccgcccgca acgataattt
    20161 tcgcttcgga gagatcaaca ccgtccgccg tttttttgac gacctcttga atcacggtgc
    20221 gaaggtcagt aagagagaca ttcacgcttt cgatgcttcc cgatctgctg gtgtcttttt
    20281 ctgaagcttg aatgttattg gggcgaattg ttgcaaagat catcggatcg gttgaaatga
    20341 cacgttcaaa agctttcccc gagtaaatcg gccgtgtgaa cacaacattt cctccggtaa
    20401 cgcttacatc tatagcatca gaaattaagc ctgtttgcag ccgggcagca agcttcggtg
    20461 aaagatcctt gcccattgcc gtatgcccga agatgactga atcaggattt tcttgctcga
    20521 taacacctct catgacctgg ctgtacccgt ctgccgtgta tgttttcagc ttcgggtcct
    20581 cagcggtaag aactttatct gctccgtaat gaataagctc ttgtgcaatg ctttgtacat
    20641 tttcaccgat gagaacaccg atgacttccc catctcctga aatggttctt cctgcagcta
    20701 ttgcttcaaa ggtgacattc cgcaattccc catcgcgtat ttctccaagc acgatcactt
    20761 tttttcccat tctaacatcc ccctgtttct ttgaatgtcc aagctttaaa tgactttagc
    20821 ttcgctgcgg agcaatgaaa caagctcttt tgcctgttca gcaggctcac cttggagaag
    20881 cttcccggct tcttttttcg gcggcagaaa acgttcaatg gttttcagct ttggttcagc
    20941 atcctcttcg tccaggtcaa gatcatcaag ttcaagctct tcaagcggct ttttcttagc
    21001 cttcataatt cccggaagcg atggatagcg cggctcgttt aagccctgct gagctgtgac
    21061 aagcaatggg agcgtcgttt tgattttttc aacatcccct tcgacgtccc tttctgcttc
    21121 tgcatcagtg ccgttgattt cgagtttggt gatcgtagtg atacacggaa tgtccagtag
    21181 ctcggcaagc cgaggcgcca cttgtcctga tcctccgtca atggcaacat ttccgccgag
    21241 aatcaaatca aactcctgat ccttcatata gtggtataaa acttgagaaa tggaatattg
    21301 gtcgggttct tcaagatcat cttctatgtt gattaaaaca gcttggtcac aacccatggc
    21361 aagcgccgta cgcaattctt tctccgcttc ttcaccgccg actgtgacag cggtgatcgt
    21421 gccgccatgc ttttccttca gctggatggc ttcttctatc gcgtactcat catatggatt
    21481 aatgatccat tccgctccgt catcctgaat ctttcctgtt tcaatgacga ttttttcttc
    21541 tgtgtcaaac gtccgtttca tcagtacaaa tagattcatg atcatatccc cttttattcg
    21601 cctttgaact gaggctttct tttttcgaga aatgcctgga tgccttcctt ggcgtcctct
    21661 gactcaaatg cttccccaaa tcgctttgct tcaagcttta agctgccttc ataggaatac
    21721 accttgttgg aataaagaag ttcaagcaaa gatgccagcg tttgcgggct tttctctgca
    21781 aacttagcgg caagtgcttt tgctttttca atcacttctg cctcatcttt cgctccaatt
    21841 gagacaagtc cgagatcaag cgcttctttt ccggatattg gttctcctga gccgatgagc
    21901 tccagtgctt tggctgtacc gacatatttc ggaaggcgct gtgtccccgc aaaacccgga
    21961 atgataccga gattaagctc cgggagcccc agcttagcat cttctgccgc gattctgatg
    22021 tgacaggcca ttgcaagctc cagcccgcct ccgagagcag cgccgtgaat cgctgcgata
    22081 atcggttttg ggaaactttc aattctctcc attaactgct ggccgcgctc agcgagcaat
    22141 gaggaatcct cattgccttt aaacgatgta aattctttaa tatcagcgcc ggctgagaaa
    22201 aatcttccct cgccgtgaat gataatgctt cgtacgcctg catctgtctc acattgatca
    22261 agacaggaag acagctcttc taatatccgg cttgaaagcg cgtttgccgg cggattgtga
    22321 atcgtcaaga ctgccacaaa ttgatcaacc gcaagtgaaa ttgcattcat aggacagaac
    22381 tcctttactt attgtgaatt ccggatacca ataattctaa aacgctgttt gaaagcgcaa
    22441 cgagatcgta cttttggtca ttcatcaccc aagttgtcac agtttcgtca atcgttccaa
    22501 aaatcatctg ccgggcgagg cggac
//
