LOCUS       c00004_gnlPro..        25412 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PANHJAPL_4.
ACCESSION   c00004_gnlPro..
VERSION     c00004_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 19:48:43
            Original ID  :: gnl|Prokka|PANHJAPL_4
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 163599
            Orig. end    :: 189011
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..25412
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[173599:179011]"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [Amidohydro_1, Amidohydro_3,
                     Arginase, FGase, Urocanase]) and Lyase_aromatic and
                     Urocanase_C)"
                     /neighbourhood="10000"
                     /product="histidine2glutamate_hutHGIU_operon"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..15412
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [Amidohydro_1, Amidohydro_3,
                     Arginase, FGase, Urocanase]) and Lyase_aromatic and
                     Urocanase_C)"
                     /neighbourhood="10000"
                     /product="histidine2glutamate_hutHGIU_operon"
                     /protocluster_number="1"
     cand_cluster    1..25412
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(3, [Amidohydro_1, Amidohydro_3,
                     Arginase, FGase, Urocanase]) and Lyase_aromatic and
                     Urocanase_C)"
                     /kind="single"
                     /product="histidine2glutamate_hutHGIU_operon"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..25412
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="histidine2glutamate_hutHGIU_operon"
                     /region_number="1"
                     /rules="(minimum(3, [Amidohydro_1, Amidohydro_3, Arginase,
                     FGase, Urocanase]) and Lyase_aromatic and Urocanase_C)"
                     /tool="gutsmash"
     CDS             591..1928
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MmgE_PrpD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_164"
                     /sec_met_domain="MmgE_PrpD (E-value: 1.2e-94, bitscore:
                     313.2, seeds: 231, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKQGLTAGLAAAVRTSQPEHSVDAIHEAKKGLLDFTAASFAGRE
                     DKGIQKLLRLIEDEGGRPLVPIIGQGKKAAPLQSAMLNGFIAHALDFDDVHSDVRGHPS
                     AVIVPALIASAARGHDERLLGAYIVGIEVMARLGESIGSRHYEKGWHNTGTLGAIAAAC
                     AVGYAEELTQEKLEKAIGFAATQSAGMRVQFGTEMKPLHAGLAAQAGLLAVKLAQSEFG
                     GSRTALDGETGFFSLYGDVEKAQHTLLNDWGAPWRIVQPGLWFKIYPFCSAAHHAADAV
                     RQLISEETISAANTERIEVIFPPGGDAALTERSPKTGEEGRFSVEYVIALALHGHDLTV
                     EHFNSQPIPNGIQTTIGHIQRVYDNATQPAPRAVPKGRFTIVRAYLSDGRICEARVDCP
                     KGAPGNELSEEDIIEKLTLTIPQEKARSIITAVEKADIKEFLAHIE"
     CDS             1998..3110
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) EutH"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_165"
                     /sec_met_domain="EutH (E-value: 9.8e-141, bitscore: 464.9,
                     seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVNDAVVFILAAFLLWGAADYCLGNRWGLGERFAAGFKAMGPLA
                     LSMIGIVSLAPVLAAILIPIVAPFYTAIGADPSSFANTILAIDMGGYALAGEMAKDPEA
                     GLFSWVFLGTMMGPAIVFTIPVALGIIEKEDHPYFAKGILIGLCTVPIGCFIGGLCAGF
                     DIGMIGKNLLIPSLLSAVIAFGLWRYTDSMIRLFHLFGKAVSVVAIIGLAAVSVETLTG
                     IVLIPGMENVETGIQTTGTIAIALAGAFPMTAFITKTFKKPLKALGKCLHLDETATAGL
                     VTSLAHHIPMLASLKDMTPRGKVINVAFAVSGAFVLGSHLGFVAGMKKEMAAAMIIGKL
                     AGGVTAAAAAAWMTPAQSAKQQKHISASHS"
     CDS             3183..4010
                     /locus_tag="ctg4_166"
                     /transl_table=11
                     /translation="MAVKDRYMSKIKQETKPWIKRFGRLGYFAFGGVFILLGVLAFMTA
                     AGAGRAKDSSGALQTLSRMPYGSLLLFLIGIGLIGYVIWMVLSAIKDTEGHGNSRRGLS
                     RRIGNFFSAAVYTSIAWNALRFVFDQGDGGTSEQTWSAYVLAQPFGQWLTGLTGAGFIV
                     FAIVQFMKGIRAAFMKEFDTSKMNKQMICITKNTGRAGNIARAIIFSAIGYFLIKTAMT
                     ADPDDTRGFDGALAELAQQPHGKLILSILALGLILYGMYAIMKGIYQHMTWEK"
     CDS             4144..5085
                     /locus_tag="ctg4_167"
                     /transl_table=11
                     /translation="MDREKQQLSIEAARLYYQSDYSQQQIAEQLNISRPTVSRLLQYAK
                     EKGYVQIRVMDPFEDLDALGSILEEKYGLLEAHVVFSPTPDYAGITHDLSRYGAEYMHE
                     TVKDGDIVGVSWGTTMYQIAQNMQPKQVKGVEVVQLKGGISHSRVNTYSAETIQLFAEA
                     FQTMPRYLPLPVVFDNADVKRMVEEDRHIERIIEMGKQANIALFTVGTVRDEALLFRLG
                     YFNEEEKALLKKQAVGDICSRFFDAKGNICSSAINDRTIGVELEDLRLKERSILVAGGS
                     RKVSSIHGALTGKYANVLIIDQHTARALVNDL"
     CDS             5191..5862
                     /locus_tag="ctg4_168"
                     /transl_table=11
                     /translation="MSLANIIDHTALKPHTQKADILKLIEEAKTYKFASVCVNPTWVEL
                     AAKELKGTGVDVCTVIGFPLGANTTETKAFETKDAISKGATEVDMVINIAALKDKEDDV
                     VEADIRGVVEAAAGKALVKVIIETCLLTDEEKERACRLAVSAGADFVKTSTGFSTGGAT
                     KEDIALMRKTVGPDIGVKASGGVRTKEDVDTMVEAGASRIGASAGVSIVKGENASGGDN
                     Y"
     CDS             5943..7124
                     /locus_tag="ctg4_169"
                     /transl_table=11
                     /translation="MKYLIGIIGLIVFLGLAWIASSGKKRIKIRPIVVMLILQFILGYI
                     LLNTGIGNFLVGGFAKGFGYLLEYAAEGINFVFGGLVNADQTTFFMNVLLPIVFISALI
                     GILQKWKVLPFIIRYIGLALSKVNGMGRLESYNAVASAILGQSEVFISLKKELGLLNQQ
                     RLYTLCASAMSTVSMSIVGAYMTMLKPEYVVTALVLNLFGGFIIASIINPYEVAKEEDM
                     LRVEEEEKQSFFEVLGEYILDGFKVAVVVAAMLIGFVAIIALINGIFNAVFGISFQGIL
                     GYVFAPFAFLVGIPWNEAVNAGSIMATKMVSNEFVAMTSLTQNGFHFSGRTTAIVSVFL
                     VSFANFSSIGIIAGAVKGLNEKQGNVVARFGLKLLYGATLVSFLSAAIVGLIY"
     CDS             7154..8455
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_trans_3N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_170"
                     /sec_met_domain="Glycos_trans_3N (E-value: 2.5e-22,
                     bitscore: 74.5, seeds: 1422, tool: rule-based-clusters)"
                     /sec_met_domain="Glycos_transf_3 (E-value: 1.9e-53,
                     bitscore: 177.6, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRMVDIIIKKQNGKELTTEEIQFFVNGYTDGSIPDYQASALAMAI
                     FFQDMSDRERADLTMAMVNSGETIDLSAIEGIKVDKHSTGGVGDTTTLVLAPLVAALDV
                     PVAKMSGRGLGHTGGTIDKLEAIDGFHVELTKDEFIKLVNRDKVAVIGQSGNLTPADKK
                     LYALRDVTGTVNSIPLIASSIMSKKIAAGADAIVLDVKTGAGAFMKTEEDAAELAKAMV
                     RIGNNVGRQTMAVISDMSQPLGFAIGNALEVKEAIDTLKGEGPEDLHELVLTLGSQMVV
                     LAKKADTLDEARAKLEEVMKNGKALEKFKDFLKNQGGDSSIVDDPSKLPQAAYQIDVPA
                     KEAGVVSEIVADEIGVAAMLLGAGRATKEDEIDLAVGIMLRKKVGDKVEKGEPLVTLYA
                     NRENVDEVIAKVYDNIRIAAEAKAPKLIHTLITE"
     CDS             complement(8498..9862)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AA_permease"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_171"
                     /sec_met_domain="AA_permease (E-value: 3e-135, bitscore:
                     447.4, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISLGGVIGTGLFLSTGYTLHQAGPGGTILAYVIGGLMMYLVMQC
                     LGELSVAMPVTGSFQKYATTFIGPSTGFMVGIMYWINWVVTVGSEFTASGILMQRWFPD
                     SSVWMWSAIFAALLFICNAFSVKLFAETEFWFSSVKIVTIILFIILGGAAMFGLISLNG
                     TADAPMLSNFTDHGGLFPNGFLAVFIAMISVSFAFSGTELIGVTAGESANPQKDIPRSI
                     RNVAWRTVIFFIGAVFVLSGLISWKDAGVIESPFVAVFAEIGIPYAADIMNFVILTALL
                     SVANSGLYASTRMMWSLANENMISSRFKKVTSKGIPLNALMISMAVSCLSLVSSIVAPG
                     TVYVVMVAIAGFAGVVVWMSIALSQLLFRKRFLKKGGNVKDLTFRTPLYPLMPIAALLL
                     CSASCIGLAFDPNQRIALFCGVPCIILCYLIYHFKRNVTKAKKISQEEYQADHIL"
     CDS             complement(10001..10960)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     histidine2glutamate_hutHGIU_operon: Arginase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_172"
                     /sec_met_domain="Arginase (E-value: 1.3e-67, bitscore:
                     224.2, seeds: 235, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LDKYPFLREAGSSFKDRDVTKMSDLIATWEGQDIKGPALIGVPLS
                     KSSISHSGASFAPGTIRQALKHSSAYSAELGEHVVSELLYDLGDIDIHVTDIVKSHHHI
                     FQTMHALLSDHPDWVPLILGGDNSISYSTIKAIAQTKGTTAVIQFDAHHDVRNTEDGGP
                     TNGTPFRRLLDEEIIKGQHLIQLGIREFSNSQAYEAYAKKHSVNIHTMDMIREKGLIPT
                     IKEILPVVQDRTDFIFISVDMDVLDQSHAPGCPAIGPGGLYTDELLEAVKYIAQQPNIA
                     GIEIVEVDPTLDFRDMTSRAAAHVLLHALKGMKLSPFK"
     CDS             complement(10953..12218)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     histidine2glutamate_hutHGIU_operon: Amidohydro_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_173"
                     /sec_met_domain="Amidohydro_1 (E-value: 1.6e-19, bitscore:
                     66.3, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKQIDTILINIGQLLTMESSGPRAGKSMQDLHVIEDAVVGIHEQ
                     KIVFAGQKGAEASYEADEIIDCSGRLVTPGLVDPHTHLVFGGSREKEMNLKLQGISYLD
                     ILAQGGGILSTVKDTRAASEEELLQKAHFHLQRMLSYGTTTAEVKSGYGLEKETELKQL
                     RVAKKLHESQPVDLVSTFMGAHAIPPEYQNDPDEFLDQMLSLLPEIKEQELASFADIFT
                     ETGVFTVSQSRRYLQKAAEAGFGLKIHADEIDPLGGAELAGELKAVSADHLVGASDEGI
                     KKLAEARTIAVLLPGTTFYLGKSTYARARAMIDEGVCVSLATDFNPGSSPTENIQLIMS
                     IAALHLKMTAEEIWHAVTVNAAYAIGKGEEAGQLKVGRSADLVIWQASNYMYIPYHYGV
                     NHVHQVMKNGTIVVNREGAILG"
     CDS             complement(12231..13889)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     histidine2glutamate_hutHGIU_operon: Urocanase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     histidine2glutamate_hutHGIU_operon: Urocanase_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Urocanase_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_174"
                     /sec_met_domain="Urocanase (E-value: 7.1e-91, bitscore:
                     299.5, seeds: 148, tool: rule-based-clusters)"
                     /sec_met_domain="Urocanase_C (E-value: 7.1e-96, bitscore:
                     315.2, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="Urocanase_N (E-value: 1.9e-62, bitscore:
                     204.6, seeds: 71, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDVKKSIRANRGTELECLGWEQEAVLRMLRNNLDPEVAEKPEDL
                     IVYGGIGKAARDWDAFHAIEHSLKTLKNDETLLVQSGKPVGMFRTHPQAPRVLLANSVL
                     VPKWADWEHFHELEKKGLMMYGQMTAGSWIYIGSQGILQGTYETFAELARQHFGGSLKG
                     TLTLTAGLGGMGGAQPLSVTMNEGVVIAVEVDEKRIDKRIETKYCDRKTASIEEALAWA
                     EEAKRAGKPLSIALLGNAAEVHHTLLNRGVKIDIVTDQTSAHDPLIGYVPESYSLDEAD
                     RLRQDNPELYVRLAKQSMKKHVEAMLAFQQKGSIVFDYGNNIRQVAKDEGLENAFDFPG
                     FVPAYIRPLFCEGKGPFRWAALSGDPADIYRTDALLKELFPTNKALHRWIDMAQEKVTF
                     QGLPSRICWLGYGERKKMGLAINELVRSGELKAPVVIGRDHLDCGSVASPNRETEAMKD
                     GSDAVGDWAVLNALVNTAAGASWVSFHHGGGVGMGYSLHAGMVAVADGSELADERLARV
                     LTSDPGMGIIRHADAGYERAVEVAKEQDIIVPMQK"
     CDS             complement(13886..15412)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     histidine2glutamate_hutHGIU_operon: Lyase_aromatic"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_175"
                     /sec_met_domain="Lyase_aromatic (E-value: 8.1e-197,
                     bitscore: 650.4, seeds: 479, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTLDGSSLTTADVARVLFDFEEAAASEESMERVKKSRAAVERIV
                     RDEKTIYGINTGFGKFSDVLIQKEDSAALQLNLILSHACGVGDPFPECVSRAMLLLRAN
                     ALLKGFSGVRAELIEQLLAFLNKRVHPVIPQQGSLGASGDLAPLSHLALALIGQGEVFF
                     EGERMPAMTGLKKAGIQPVTLTSKEGLALINGTQAMTAMGVVAYIEAEKLAYQTERIAS
                     LTIEGLRGIIDAFDEDIHSARGYQEQIDVAERIRFYLSDSGLTTSQGELRVQDAYSLRC
                     IPQVHGATWQTLGYVKEKLEIEMNAATDNPLIFNDGDKVISGGNFHGQPIAFAMDFLKI
                     SISELANIAERRIERLVNPQLNDLPPFLSPHPGLQSGAMIMQYAAASLVSENKTLAHPA
                     SVDSIPSSANQEDHVSMGTIAARHAYQVIANTRRVIAIEAICALQAVEYRGIEHAASYT
                     KQLFQEMRKVVPSIQQDRVFSYDIERLTDWLKKESLIPDHQNKELRGMNI"
     CDS             complement(15525..15980)
                     /locus_tag="ctg4_176"
                     /transl_table=11
                     /translation="VIHMTLHKERRIGRLSVLLLLNEAEESTQVEELERDGWKVCLGKV
                     GSMDAHKVVAAIETASKKSGVIQSEGYRESHALYHATMEALHGVTRGEMLLGSLLRTVG
                     LRFAVLRGNPYESEAEGDWIAVSLYGTIGAPIKGLEHETFGVGINHI"
     CDS             16488..17897
                     /locus_tag="ctg4_177"
                     /transl_table=11
                     /translation="MFNRLFRVCFLAALIMAFTLPNSVYAQKPIFKEVSVHDPSIIETS
                     GTFYVFGSHLASAKTNDLMQWQQLTTSVSNDNPLIPNVYKELKDTFEWAQSDTLWAADV
                     TQLADGKYYMYYNACRGDSPRSAMGVAVADNIEGPYKNKGIFLKSGMEGTSSDGTPYDA
                     TKHPNVVDPHTFFDKDGKLWMVYGSYSGGIFILEMNPKTGFPLPGQGYGKKLLGGNHSR
                     IEGPYVLYNPDTQYYYLYLSYGGLDATGGYNIRVARSKKPDGPYYDAEGNPMLDVRGKE
                     GTFFDDRSIEPYGVKLMGSYTFETENEKGTGYVSPGHNSAYYDEKTGRSYLIFHTRFPG
                     RGEEHEVRVHQLFMNKDGWPVATPYRYAGETLKEVKQKDITGTYKLIQHGKDISADIKQ
                     TINIQLNKNHTISGEMTGTWEKTGKNTANITLAGKKYNGVFLRQWDSVREKNVMTFSVL
                     NGNGEAVWGSK"
     CDS             18203..18568
                     /locus_tag="ctg4_178"
                     /transl_table=11
                     /translation="MHSEMLLHSVKADLHEKQEQIHQLKRVLHEIRQIKHEFSEAQHLI
                     HWPHLNREAWRGTHAERFEDIREGMNKAYHQIKSEQVSGIIESIEGKIDSLEGDVYSIR
                     RQITRIEHEIENEKHKK"
     CDS             18580..18849
                     /locus_tag="ctg4_179"
                     /transl_table=11
                     /translation="MAQEIKMVYGTVKQGLSQLKNSAELKSSLPGHLSGRNHLNVVKSI
                     EQLNEDIKELTEAYASVLAKHIAQTESAVNAMKETDENISSSMK"
     CDS             18869..20434
                     /locus_tag="ctg4_180"
                     /transl_table=11
                     /translation="LKTLDVHALHEGIQHTIEKLDKQKQQLEKLEKSVEHLAGMKDALK
                     GKGGDAIRTFYEECHKPFLLFFGMFIDEYKKVLKQTQHAISSVESDSHGMIAEAFLSHD
                     ARHGVKHAREVTEQLTDAVNRQTSAIGHIVSLPAVNDIFFRMETEQAERLISDTLNKLF
                     QFDGQQTQALETAKSDFQTMKKYMDQLGTMYTGPKIEITGYKSGSILKSQEEENINQTF
                     GAINPQMKQADDSPMEMMLKKLAENEKSKVDSVVKTGDSKKVSKNIIVINGKVYNTSEH
                     REHIKTDFSNAEVKQVVYNDTLYNVYISGNDMKLEPVVSLSDIKVDENGYVKILETAVE
                     FSGINDLFRAATGRDPITGEKVSSKDRIVATVHAVPISKIAKLQKFNIYKLINGEKKTK
                     KASKIEKGTKKNKNDKVLTKNGAFRDAKRRAGIPNSSQHKKPVDVFDGTSENRRVYEFE
                     VDGKKKYIIEHREDKLGRGPHFHGADDLKGNPLEKGRYNQYPGHSPEDFEGYKNKGKFK
                     KKGD"
     CDS             20462..20932
                     /locus_tag="ctg4_181"
                     /transl_table=11
                     /translation="MELLKRKSRRKNLIRELDFLHITEDSFLDIEENELFCKKAFSILD
                     TKQNKVQIQGTDYIENIQKSIQLLKDTFENVELGSNEARLLFFRENEIEAVLLSLDEIF
                     INLDKVLEITKFSIGYGDFILTSEDFKFGLCIERTEYHYEFCVWGLSEKNKK"
     CDS             21420..21722
                     /locus_tag="ctg4_182"
                     /transl_table=11
                     /translation="MLSINKQDDPVFQFLAGTFHQDIETPDDAIQELLTEESKEYLEDA
                     IVFLTDFIESEHSENEKNDYIQSCADGVYFPAFNLEPIDWLKNVIVQIKKPLNKI"
     CDS             22112..23941
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTS_EIIC"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_183"
                     /sec_met_domain="PTS_EIIC (E-value: 7.8e-39, bitscore:
                     129.5, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYDKLSKDILQLVGGEDNVQCVIHCMTRLRFNLHDNSKADRSQL
                     EQLPGVMGTNISGEQFQIIIGNDVPKVYQAIVRHSNLSDEKSAGSSSQKKNVLSAVFDV
                     ISGVFTPILPAIAGAGMIKGLVALAVTFGWMAEKSQVHVILTAVGDGAFYFLPLLLAMS
                     AARKFGSNPYVAAAIAAAILHPDLTALLDAGKPISFIGLPVTAATYSSTVIPILLAIWI
                     ASYVEKWIDRFTHASLKLIVVPTFTLLIVVPLTLITVGPLGAILGEYLSSGVNYLFDHA
                     GLVAMVLLAGTFSLIIMTGMHYAFVPIMINNIAQNGHDYLLPAMFLANMGQAGASFAVF
                     LRSRNKKFKSLALTTSITALMGITEPAMYGVNMRLKKPFAAALIGGAAGGAFYGMTGVA
                     SYIVGGNAGLPSIPVFIGPTFIYAMIGLVIAFAAGTAAAYLLGFEDVPSNGSQQPAVHE
                     GSREIIHSPIKGEVKALSEVKDGVFSAGIMGKGFAIEPEEGEVVSPVRGSVTTIFKTKH
                     AIGITSDQGAEILIHIGLDTVKLEGQWFTAHIKEGDKVAPGDPLVSFDLEQIKAAGYDV
                     ITPVIVTNTDQYSFSPVKEIGKVQPKEALLALS"
     CDS             23928..25373
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_184"
                     /sec_met_domain="Glyco_hydro_1 (E-value: 2.4e-150,
                     bitscore: 496.8, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LLYLEKTNGVINMSSNEKRFPEGFLWGGAVAANQVEGAYNEGGKG
                     LSTADVSPNGIMSPFDETMTSLNLYHNGIDFYHRYKEDIALFAEMGFKAFRTSIAWTRI
                     FPNGDEEEPNEDGLRFYDDLFDELLKHHIEPVVTISHYEMPLGLVKKYGGWKNRKVIEF
                     YERYAKTVFKRYQHKVKYWMTFNEINVVLHAPFTGGGLVFEEGENKLNAMYQAAHHQFV
                     ASALAVKAGHDIIPDSKIGCMIAATTTYPMTSKPEDVFAAMENERKTLFFSDVQARGAY
                     PGYMKRYLAENNIEIEVAEGDEELLKEHTVDYIGFSYYMSMAASTDPEELAKSGGNLLG
                     GVKNPYLKSSEWGWQIDPKGLRITLNTLYDRYQKPLFIVENGLGAVDKVEEDGTIQDDY
                     RINYLRDHLIEAREAIADGVELIGYTSWGPIDLVSASTAEMKKRYGFIYVDRDNEGHGT
                     FNRIKKKSFNWYQQVIATNGESL"
ORIGIN
        1 atcgtcatca aagggaaagg cggacacgcc ggcatcccga ataacagtat tgatccaatc
       61 gctgcaaccg gacaaatcat cagcgggctg caatctgtgg tcagccgcaa tatcagctca
      121 ctgcaaaacg cagtcgtcag tatcacaaga gtacaggcgg gcacctcgtg gaacgtaatt
      181 ccagaccaag ctgaaatgga ggggacggtt cgaacctttc aaaaagaagc gcggcaggct
      241 gttccggagc atatgagacg agtggctgaa ggaattgcag cgggctatgg ggcacaagca
      301 gaattcaagt ggtttcctta tttgccttcc gttcagaatg acggcacatt tttgaatgcg
      361 gcatccgaag ctgcggcacg gcttggctat caaaccgttc acgctgagca gtctccgggc
      421 ggagaagact tcgctctgta tcaagagaag attccgggat tttttgtctg gatgggaacg
      481 aacgggacgg aggagtggca tcatccggcc tttacactgg atgaagaagc ccttacggtt
      541 gcctctcaat actttgcgga gctggcggtt attgtattgg agaccatcaa atgagcaaac
      601 aagggctgac agcaggtctt gcagcggctg tgagaacgtc acaacctgag cattcagttg
      661 acgcgattca cgaagcaaaa aagggattac ttgattttac tgccgcttca ttcgcaggaa
      721 gagaagataa aggaattcaa aagctcctcc gtctgataga ggatgaagga ggccggcccc
      781 ttgttcctat tatcggacag ggcaaaaagg ccgcaccatt acaatccgcg atgctgaatg
      841 gatttatcgc ccatgcattg gattttgatg atgtccactc cgatgtaaga ggacacccca
      901 gtgcagtcat cgtaccggcc cttattgctt ctgccgctcg cggacatgac gagcggcttc
      961 ttggcgctta tattgttggt attgaagtga tggcacggct gggagaatca attggcagcc
     1021 gccactatga aaagggctgg cataatacag gaacgcttgg tgccatcgct gctgcctgcg
     1081 ccgtaggtta tgctgaggag ctgactcagg aaaagctgga aaaagcgatt ggttttgcgg
     1141 ctacgcaatc tgctgggatg agggtgcaat ttggaacaga aatgaaaccg ctgcacgccg
     1201 gtctggcggc tcaggctggc ttgctggccg ttaagctggc ccaatcagaa tttggcgggt
     1261 cccgcacggc acttgatgga gaaactggtt tcttcagtct gtacggtgac gttgaaaaag
     1321 cacaacatac tttgctaaac gattgggggg caccgtggag aattgtgcag ccgggtctat
     1381 ggtttaaaat ctatccattt tgttccgcgg cacaccatgc tgcagatgcg gtacgacagc
     1441 ttatctccga agaaaccatt tctgcggcca ataccgaacg tattgaagtg atatttccgc
     1501 caggcggaga tgctgcattg acggaacgat ctccaaaaac tggagaggaa ggccgtttca
     1561 gcgttgaata tgtgattgct cttgctttgc acggacacga cctgaccgtt gaacatttca
     1621 acagccagcc gatcccaaac ggcattcaaa cgacaatagg gcatattcag cgcgtatatg
     1681 acaatgctac tcagccggct ccccgtgccg ttccaaaagg ccgttttacg attgtccggg
     1741 cctatttatc agacggccgg atttgcgaag cgcgtgtgga ctgcccaaaa ggggcgccag
     1801 gaaatgagct gtctgaagaa gacataatag aaaaattgac attaacgatc ccgcaagaaa
     1861 aagcgcggag catcataaca gccgttgaaa aagccgatat aaaagaattt ttagctcata
     1921 ttgaataaga tcaactctat tcggtgattt cagatgatat gataaaacca atcatacgtt
     1981 tgaaaaagga gaaaaccatg acggtgaatg acgcggttgt attcattttg gctgcctttt
     2041 tactatgggg agcggcggat tattgtttgg gaaacagatg ggggctaggc gagcggtttg
     2101 cggccgggtt taaggctatg gggccgctgg cgctgtccat gatcggaatt gtgtcgctgg
     2161 cgcccgtgct ggcagcaatc ctgattccca ttgttgctcc gttttacaca gcgattggcg
     2221 cggacccttc ttcctttgcg aacaccattt tggcgattga tatgggagga tatgcgctgg
     2281 ctggagaaat ggcgaaagat ccggaggccg ggctgttttc atgggtgttt ttaggaacaa
     2341 tgatgggacc ggcaatcgtc ttcacgattc ccgtcgctct tggcatcatc gaaaaagagg
     2401 atcatccgta ttttgcgaaa ggcatattaa tcgggctgtg cacagtgccg atcggttgtt
     2461 tcatcggcgg attatgcgcg ggctttgaca tcggcatgat aggtaaaaac cttctgatcc
     2521 cgagtctgtt atctgctgtg atcgcttttg gattatggcg gtataccgac agtatgattc
     2581 ggttgtttca tctcttcggg aaagcggtca gtgtggttgc gattatcggg cttgcggctg
     2641 tctccgttga aacgctgaca ggcattgtgc tgattccggg aatggagaat gtcgagacag
     2701 ggatacaaac gacagggacc attgccattg ctctggcagg ggcatttccg atgacggctt
     2761 ttattacaaa aacctttaaa aaaccgctaa aggctctggg gaaatgcctt catttagatg
     2821 agacagcaac agcaggcttg gtgacctctt tggcgcacca tatcccaatg ctggcttcat
     2881 taaaggatat gacgccgaga ggaaaggtca tcaatgtcgc gtttgcggtc agcggcgcct
     2941 ttgtactcgg cagccacctc ggttttgtgg ctggaatgaa aaaagaaatg gcggcggcca
     3001 tgatcattgg gaaattagca ggcggagtca cagctgccgc agcggctgct tggatgacac
     3061 ctgcacaatc agctaaacag caaaaacata tctcagccag ccatagctga ggcagaagct
     3121 gtttcaactt tgtccaatcg ggaatgttac agtaaagatt tctgtgaaag agggttggac
     3181 acatggcggt gaaagaccgg tacatgtcaa aaataaaaca ggaaaccaag ccttggatca
     3241 aacgattcgg gaggcttggt tattttgcat tcggcggcgt ttttattctg cttggggttt
     3301 tggcttttat gacggctgcc ggggcaggcc gcgccaaaga ttcgagcgga gctctccaaa
     3361 cgctatcacg catgccgtat gggtcactat tgcttttttt aataggcatc ggccttatcg
     3421 gctatgtaat ctggatggtg ttaagtgcga tcaaggacac ggaggggcac ggaaacagca
     3481 ggcgaggcct ttcacggaga ataggaaact ttttcagtgc cgccgtttac acatccatcg
     3541 cttggaatgc cttgcgattt gtgtttgacc aaggggacgg cggcacttca gaacagacgt
     3601 ggtccgctta tgtattggcg cagccgttcg gccaatggct cacagggctt acgggtgcgg
     3661 gttttatcgt atttgcgatt gttcaattta tgaaaggcat tcgggcagct tttatgaaag
     3721 aatttgatac gtcaaaaatg aacaaacaaa tgatatgcat cacgaaaaac accggacgcg
     3781 caggcaatat cgcccgggcc attattttct cagctatcgg ctattttctc atcaagacag
     3841 ccatgaccgc tgatcccgac gacacaagag gctttgacgg cgcgctcgcc gaactcgcgc
     3901 agcagccgca tggcaaattg attctgtcta tattggcatt aggcctgatc ctatatggaa
     3961 tgtacgccat tatgaaaggc atttatcagc acatgacttg ggagaagtaa gctctgggca
     4021 ggtccgcgcc cagagcgttt ttcagtttct tagaaatcag gtggatgaaa gccggcgcca
     4081 gcctgtataa taaaagcaaa tcaaaagcag ttttatcagg actgatccac agggaggtgc
     4141 ggaatggatc gggaaaaaca acaattaagc atagaagcgg caaggcttta ctatcagtct
     4201 gactacagtc agcagcaaat tgctgagcag ctcaacattt caaggccaac cgtttcccgg
     4261 ctgctgcaat atgcaaagga aaaagggtat gtccagattc gcgtcatgga cccttttgag
     4321 gatttggatg cgctcggttc catccttgaa gagaaatacg ggctccttga ggcgcatgtt
     4381 gtgttttccc cgacacccga ttatgcagga attacacatg acctaagccg ctatggtgca
     4441 gaatatatgc atgaaacggt aaaagacggc gacattgtcg gcgtcagctg gggaactacc
     4501 atgtatcaaa tcgcgcaaaa tatgcagccg aagcaggtaa aaggcgtcga ggtcgtccag
     4561 ctgaaaggcg gcatcagcca ttcccgggta aacacgtatt cagctgaaac gattcagctg
     4621 tttgcagagg cttttcaaac gatgccgcgc tatcttccgc ttcccgtcgt gtttgataat
     4681 gcggatgtga agcgaatggt ggaggaagac cgtcatattg agcggatcat cgagatggga
     4741 aagcaggcga atatcgctct cttcacggtg gggactgtcc gtgacgaagc gctgttgttc
     4801 cggctcggat attttaacga agaagagaaa gccctgctga aaaaacaggc cgtgggggat
     4861 atttgttcac gcttttttga tgcgaaaggg aatatttgca gcagcgccat caatgaccgg
     4921 accatcggtg ttgagcttga agacctcagg ctgaaggaac gctccatttt agttgccggc
     4981 ggaagcagaa aagtatcttc cattcacgga gcattaaccg gaaaatatgc caacgtttta
     5041 atcattgacc agcataccgc gagggcgctt gttaatgatt tgtgacacgt tcaaaccttt
     5101 cattgaacaa aatttcaatt accaatttac atatgttcaa aagtcggtta tgctaaaaaa
     5161 tatcttaaca aaaaaggaag tgtgcgaagg atgtcattag ccaacataat tgatcataca
     5221 gctttgaaac cgcatacaca aaaagcggac attctaaaac taattgaaga agcgaaaaca
     5281 tacaaatttg cttcagtatg tgtcaatccg acatgggtgg agcttgctgc aaaagagctt
     5341 aagggaactg gagtcgacgt ttgtacggtc atcggcttcc cgctcggtgc caatacaact
     5401 gaaacaaaag cgttcgaaac aaaagacgcc atttcaaaag gcgccactga agtggatatg
     5461 gtcattaata ttgccgcttt aaaagacaag gaagacgatg tggtggaagc tgatatccgc
     5521 ggtgtagtgg aagctgcagc cggaaaagcg cttgtcaaag tcattatcga aacgtgcctt
     5581 ctgactgatg aagaaaaaga acgtgcatgc cgtttagcgg tgtctgcggg agcggatttc
     5641 gtaaaaacat caacaggctt ttctacaggc ggcgcaacga aggaagatat cgccttaatg
     5701 cgcaaaacag taggacctga tatcggcgtg aaagcatctg gcggcgtcag aacgaaagaa
     5761 gatgtagaca caatggtaga ggccggagca agccgaattg gcgccagcgc aggcgtttct
     5821 atcgtaaaag gagaaaatgc atcaggagga gacaactatt aagagctgac ggaaggcaga
     5881 ctgctttccg ttttctgagg aaacagtgat tgtaagcgaa tacaaataaa ggagaaacac
     5941 atatgaagta tttgattggg attatcggtt taatcgtgtt tttaggcctc gcgtggatcg
     6001 cgagcagcgg caaaaaaaga attaagatcc gcccaattgt tgttatgctc attttgcaat
     6061 ttattcttgg ctacattctc ctcaataccg ggatagggaa tttcctcgta ggaggatttg
     6121 caaaaggttt cggttacctg cttgaatacg cggcagaggg aattaacttt gtgtttggcg
     6181 gcttggtgaa tgcggaccaa acgacattct ttatgaatgt tctcttgcca atcgtgttta
     6241 tttccgctct gatcgggatt ctgcaaaagt ggaaagtcct cccgtttatt attagatata
     6301 tcggccttgc cctcagcaag gtaaacggta tgggaagatt ggaatcgtat aacgcagtgg
     6361 cttctgcgat tttagggcag tcagaagtat ttatctcctt gaagaaagaa ctcggtcttt
     6421 taaatcagca gcgcttgtac acgctttgtg catctgcgat gtcaactgta tcaatgtcga
     6481 ttgtcggcgc gtatatgaca atgctgaaac cggaatatgt tgtaacagcg ctggtcttga
     6541 acttatttgg cggtttcata attgcttcta ttattaatcc gtacgaggtt gcaaaagaag
     6601 aggatatgct tcgtgttgag gaagaagaaa aacaatcctt cttcgaagtg ctcggagaat
     6661 acatccttga cggtttcaaa gtagcggttg tcgtcgctgc gatgctgatt ggatttgtcg
     6721 cgattattgc cttgatcaat ggcattttta atgcagtatt cggtatttcg ttccaaggca
     6781 ttcttggata tgtgtttgct ccattcgctt ttcttgtcgg tatcccatgg aatgaagctg
     6841 ttaatgctgg aagcattatg gcaacaaaaa tggtatcgaa tgaatttgtc gccatgacgt
     6901 cgcttacgca aaacggtttc catttcagcg gccgtacaac agcgatcgta tcggtattcc
     6961 ttgtgtcatt tgcgaacttc tcctcaatcg gaatcattgc cggtgccgta aaaggactga
     7021 atgaaaagca aggaaatgtc gtcgctcgtt tcggcttgaa attattatac ggtgctacgc
     7081 ttgtcagctt tttatcagca gcaattgtgg gcttgattta ctgaacttaa tcgaaaagga
     7141 tcggtgacca aacatgagaa tggtagatat catcatcaaa aaacaaaacg gaaaagaact
     7201 caccactgaa gaaattcaat ttttcgtgaa cggctacaca gacggaagca ttcctgatta
     7261 tcaggcaagc gcgcttgcta tggcgatttt cttccaggat atgagtgacc gtgaacgcgc
     7321 ggacttgacg atggctatgg tgaactccgg tgaaacgatt gatctttctg ccattgaagg
     7381 aattaaagtg gataaacact ccaccggcgg cgtcggcgac acgacaacac tcgttctcgc
     7441 tccgcttgtt gcggctcttg acgtgccggt tgccaaaatg tccggccgcg gcctcggcca
     7501 tacgggcggc acgattgata agttagaggc aatcgacggc ttccacgtgg aactgacgaa
     7561 ggatgaattt attaaacttg tgaaccgcga caaggttgcg gtcatcggcc aaagcggcaa
     7621 tttaacgccg gctgataaaa aactgtacgc gcttcgtgat gtaacgggaa cggtcaattc
     7681 cattccgctc attgcaagct cgattatgag caaaaaaatc gctgccgggg cggacgccat
     7741 cgtgcttgac gtaaaaacgg gagcgggtgc cttcatgaaa acagaagaag acgcagctga
     7801 acttgccaaa gcgatggtac gcatcggaaa taacgtcggc cgtcaaacaa tggctgtcat
     7861 ttcagacatg tcccagccac tcggctttgc gatcggaaat gcgcttgaag tcaaagaagc
     7921 gatcgacacg ctcaaaggcg aggggcctga ggatcttcat gagcttgtct taacgctcgg
     7981 cagccagatg gttgtgcttg cgaaaaaagc cgatacattg gacgaagcga gagcgaagct
     8041 ggaagaagtc atgaaaaacg gcaaagcact tgagaaattc aaggatttcc tgaaaaacca
     8101 aggcggcgac agctcaattg ttgacgatcc gtctaagctt ccgcaagccg catatcaaat
     8161 tgatgtgcct gccaaagaag cgggtgtcgt ctctgaaatc gttgcggacg aaatcggcgt
     8221 cgcggcgatg ctgttaggtg ccggtcgcgc cacaaaagaa gatgagatcg atttagccgt
     8281 cggcatcatg ctccgcaaga aggtcggcga caaagtagaa aaaggcgaac cgcttgtgac
     8341 gctttacgcc aaccgcgaaa acgttgatga agtcatcgca aaagtctatg acaacatccg
     8401 catcgccgcg gaagcgaagg cgccgaagct gattcatacg ttgattactg aataaaaata
     8461 aagcacatcc catcctgagc ggggtgtgct tttttgatta caggatgtga tcagcctgat
     8521 attcctcttg gctgattttt ttcgcttttg taacatttct tttgaaatgg tagatcagat
     8581 agcaaaggat gatacaagga actccgcaga aaagtgcgat tctttgattg ggatcaaaag
     8641 caagaccgat acaagaagct gagcataata aaagagcggc tataggcata agaggataaa
     8701 gcggcgtgcg aaatgtcaga tcttttacat tccccccttt tttcagaaat ctctttcgaa
     8761 acaagagctg ggacaaggca atgctcatcc agaccacgac tcctgcaaat ccagcaattg
     8821 ctaccatcac cacatagaca gttccagggg ccacgatact ggaaacgaga gataaacaag
     8881 atacagccat actgatcatt aaggcattta aaggaatgcc tttagatgtc actttcttaa
     8941 aacgggagct gatcatgttt tcatttgcta acgaccacat catacgggtc gaagcatata
     9001 agcctgagtt ggcgacagac agcaaggctg ttaatatcac gaaattcata atatcagcag
     9061 cgtaagggat tccgatctcc gcaaatacgg cgacaaacgg gctttcaatc acgcctgcgt
     9121 ccttccacga aattaacccg gataatacga acacagcgcc aatgaaaaaa atcacggttc
     9181 tccatgcgac attacggatg gatcgcggta tatccttttg aggatttgct gattctcctg
     9241 ctgtaacgcc gattaactct gtaccggaaa aggcgaagct cacagatatc atcgcgataa
     9301 aaacggcaag aaagccattc ggaaacagcc cgccatggtc cgtgaagttt gacaacatag
     9361 gagcatccgc cgttccgttt aaagagatca ggccaaacat ggcggctcct cctagaatga
     9421 taaataaaat aatggtgaca atctttacgc tggaaaacca aaattcagtt tccgcaaata
     9481 acttaactga aaatgcgttg catataaaaa gaagggctgc aaaaatcgca ctccacatcc
     9541 atacactgct gtcagggaac cagcgctgca tgagaatacc ggatgcggta aactcagagc
     9601 ctaccgtcac cacccaattg atccagtaca tgatgccgac cataaaaccg gtagatggac
     9661 cgataaatgt tgtagcatat ttttgaaaag agccggtcac cggcatggca accgacaatt
     9721 cgccgagaca ttgcatgacg aggtacatca tcaacccgcc gattacataa gcgagtatcg
     9781 taccgccggg tccggcttga tgtagcgtat agcccgtact gaggaaaagt cctgtgccta
     9841 tgacgcctcc caatgagatc ataaataggt gcctgctttt cattgtgcgt tttagctgtt
     9901 ggctgctgtt ctcctgaaga ttcactgtct cgccctcctt ttagctgcca ttcctaaggc
     9961 agatgagttt cttataccca aaatacaacc tgccagaaga tcacttgaat ggggagagtt
    10021 tcattccttt taatgcgtgt aacagaacat gagctgcagc tctgcttgtc atatctcgaa
    10081 aatcgagggt agggtcgact tcaacaattt caatcccggc aatattgggc tgttgtgcga
    10141 tgtacttgac tgcttcaagc aattcgtctg tatagaggcc gcccgggcca atcgctggac
    10201 agccgggtgc atgggactgg tctaagacat ccatgtcaac agatataaaa atgaaatctg
    10261 ttctatcttg aacaacaggc aaaatctctt ttatcgttgg gattagtcct ttttcgcgga
    10321 tcatgtccat cgtgtgaatg ttcacgctat gtttttttgc atatgcttca taggcctggc
    10381 tgttgctgaa ttctctgata cccagctgga tcaaatgttg acctttaata atctcttcat
    10441 ccaaaaggcg gcggaagggg gtgccgtttg tcggcccccc gtcctccgta ttgcgaacat
    10501 cgtgatgggc atcaaattga atcaccgctg tcgttccttt tgtttgtgct atcgctttta
    10561 ttgtggagta gctgatagag ttatctcccc caagtatgag cggcacccaa tccggatggt
    10621 ccgaaagcag agcgtgcatg gtttggaaaa tgtgatgatg tgactttacg atatcagtga
    10681 catgaatatc gatatccccc agatcatata gaagctctga tacgacgtgc tctccaagct
    10741 cagcagaata ggctgatgaa tgtttcagag cctggcgtat tgttccgggt gcaaaggaag
    10801 cgcctgaatg actgatggag gattttgata gggggacacc tatcaacgcc ggtcccttaa
    10861 tgtcctggcc ctcccatgtt gcgatcaggt cgctcatttt tgtgacatcc cggtctttaa
    10921 acgaagatcc ggcctctctg agaaaagggt acttatccaa gaatggctcc ctccctgttg
    10981 acaacaattg ttccgttttt catgacttga tgtacatgat tgaccccgta gtgatacgga
    11041 atatacatat agttcgaggc ttgccaaatg actagatcag ctgagcggcc gactttgagc
    11101 tgaccggctt cctctccttt ccctatggcg tatgcggcat tgactgtgac cgcatgccaa
    11161 atttcttctg cagtcatttt cagatgaagc gcggcaatgg acataatcag ctggatattt
    11221 tcagtcggcg agctgccagg attaaaatcc gttgccaagc tgacacatac accttcatca
    11281 atcatagctc tagccctggc gtatgtgctt ttgccaagat aaaatgtcgt gcccggtaag
    11341 aggacggcga tcgttcttgc ctcagccaat ttctttatgc cttcgtccga tgcacctacc
    11401 aaatggtcgg ctgagacggc ctttagctca cctgctaatt cagcgcctcc aagcggatcg
    11461 atttcatctg cgtgtatttt taatccgaag cctgcctcag ctgctttttg taaataacgg
    11521 cgggattggc tgactgtaaa aacgcctgtt tctgtaaaaa tatcagcaaa gctggcgagc
    11581 tcctgctctt tgatttccgg caaaagggaa agcatttgat ccagaaattc atctggatcg
    11641 ttttgatatt cgggaggaat cgcatgggct cccataaatg tggaaacaag gtcaacaggc
    11701 tggctttcat gcagtttctt tgcgacacgc aactgtttga gctctgtctc tttttccaag
    11761 ccgtagccgc ttttcacttc tgctgtggtt gtgccgtagg acagcattct ttgcagatga
    11821 aaatgggctt tttgcagcag ctcttcttct gaagccgccc tggtatcctt gactgtagac
    11881 agaatcccgc cgccctgcgc cagaatatcc aaatatgaaa tgccctgaag cttaaggttc
    11941 atctcctttt cacgagatcc gccaaataca agatgggtgt gcggatcaac gaggccaggc
    12001 gttacaaggc gtcccgaaca gtcaatgatt tcgtctgcct cgtaactggc ttcagcccct
    12061 ttttgtccgg cgaacacaat tttctgttca tggatgccga caacagcgtc ttcgatcaca
    12121 tgaagatcct gcatgctttt gcctgcccgc gggccgctgc tttccattgt caaaagctga
    12181 ccgatgttga tgagaatcgt atcaatttgc tttggcatgt catcactcct ttatttttgc
    12241 atcggcacga taatgtcctg ttccttcgct acttcaacgg cacgttcata acccgcatcc
    12301 gcatgacgga taatgcccat tcctgggtcg ctcgttaaga cccgcgcgag ccgctcgtca
    12361 gccagctcac ttccatcggc cactgcaacc atgccggcat gcagggaata gcccattccg
    12421 acgccgccgc catggtggaa ggaaacccag cttgcacccg ccgccgtgtt gacaagcgca
    12481 tttagcacag cccagtcacc aacagcgtca cttccgtcct tcatcgcttc tgtctcccgg
    12541 tttggagagg cgacagaccc gcagtccaaa tgatctctcc caataacgac aggcgctttt
    12601 agctccccgc ttctaaccag ctcgttaatg gcgaggccca tcttttttcg ttctccatat
    12661 ccaagccagc agatacggga cggcaaacct tggaaggtga ctttttcctg tgccatatca
    12721 atccagcggt gaagggcttt atttgtcggg aacagctctt ttaataacgc atccgtacgg
    12781 taaatatctg ccggatctcc ggaaagcgcc gcccaacgga acggcccttt tccttcacag
    12841 aataaggggc ggatgtaggc agggacaaaa cccggaaaat caaaggcatt ctccagccct
    12901 tcatcctttg cgacttgccg gatattgttg ccgtagtcaa atacaataga gcccttttgc
    12961 tgaaaggcca gcatggcttc gacatgtttt ttcatgcttt gcttcgcaag gcgcacgtaa
    13021 agctctggat tgtcttgacg caaacggtca gcttcatcaa gggaatagct ctcgggaaca
    13081 taaccgatta aagggtcatg ggcagatgtc tgatctgtca caatatcaat tttgacgcct
    13141 cggttcaaca gtgtgtgatg cacctcagct gcgtttccga gaagtgcaat ggacaaaggt
    13201 tttcctgccc gctttgcctc ttcagcccaa gctaaggctt cctcaatcga tgctgttttt
    13261 cgatcgcagt attttgtttc gatccgcttg tcgatgcgtt tctcgtcaac ctcgacggca
    13321 atcacgacgc cttcattcat cgtgactgac agcggctggg cgcctcccat tccgccgaga
    13381 cccgctgtca gcgtcaacgt tccttttaag ctgcccccga agtgctgtcg cgccagctca
    13441 gcgaaggttt cataggttcc ttgcaatatg ccttgtgagc caatgtaaat ccagctgcca
    13501 gccgtcatct gtccgtacat cattaaccct tttttctcaa gttcgtggaa atgctcccag
    13561 tctgcccact tcggaacaag aacagaattt gctaggagca cgcgtggggc ctgcgggtgt
    13621 gtacggaaca tgccaacggg ctttccggat tgcacgagca atgtttcatc attttttaat
    13681 gttttcaagg aatgctcaat ggcgtgaaaa gcgtcccaat cccgtgcggc tttgccaatc
    13741 ccgccatata cgatgaggtc ctccggcttc tcggcgactt ctggatcaag gttgtttcga
    13801 agcatccgaa gcactgcctc ttgctcccat cctaagcatt caagctctgt tcctctgttg
    13861 gcacggattg atttttttac atcagtcata tgttcatccc ccttagttcc ttattctgat
    13921 gatcaggtat taaagattct ttcttcagcc agtcagtcaa acgttcaatg tcataggaaa
    13981 aaacacgatc ctgctgaatg gacggcacga cttttctcat ttcctgaaaa agctgtttcg
    14041 tataggacgc cgcatgttct atgcctctgt attcaacagc ctgcaatgcg caaatggctt
    14101 cgatcgcaat gactctcctt gtatttgcga tcacctgata agcatgccga gcggcgatgg
    14161 ttcccatgct gacatggtcc tcttggttgg cggatgacgg aatggaatcc acacttgcag
    14221 gatgggccag tgttttattt tcagaaacga gtgaggccgc ggcgtactgc atgatcattg
    14281 caccggattg cagaccggga tgagggctca ggaacggcgg caggtcattc agctgcggat
    14341 tcacaagtcg ttcgatccgg cgctctgcga tattcgcaag ctctgatatt gagattttca
    14401 gaaaatccat ggcaaaggcg atcggctgtc cgtgaaagtt tccgccggaa atcactttgt
    14461 caccgtcatt gaaaatgagt ggattgtctg tagctgcgtt catttcaatc tctaattttt
    14521 ctttgacata gcctagtgtc tgccaagtcg caccgtgtac ttgcggaata cagcgcaatg
    14581 aataggcatc ctgaacccgc agttctccct gagaggttgt cagaccgctg tcagacagat
    14641 agaagcgaat tcgttctgcg acatcgatct gctcctgata gccgcgggct gagtgaatat
    14701 cctcgtcaaa tgcatcgata attccccgca aaccttcaat cgttaagctg gcaatgcgtt
    14761 ctgtttgata ggctagtttc tcagcttcaa tgtaggcgac cactcccatt gcagtcatgg
    14821 cctgagtccc gttaatcaag gcaagccctt ccttggatgt cagcgttacc ggttgaatac
    14881 cggctttttt caagcctgtc attgccggca ttctttcccc ctcaaaaaag acttctcctt
    14941 gtccgatcag cgcaagcgcc aggtgggaaa gcggcgccag atctccgctt gcgccaagtg
    15001 atccctgctg ggggatgaca ggatggacgc gtttatttaa aaaagcaagc aactgttcga
    15061 tcagctcagc gcggacaccg gaaaagcctt ttaacagcgc attggcgcgc aaaagcagca
    15121 ttgccctgga cacacactca ggaaaagggt cgccgactcc gcaggcatga gaaaggatta
    15181 aattcagctg cagcgccgcc gagtcttctt tctgaatcag gacatcgctg aatttgccaa
    15241 atccggtgtt gatgccgtag attgtctttt cgtcgcgtac aatccgttcc actgccgctc
    15301 tgcttttttt cacgcgctcc atactttcct cagaagccgc tgcctcctca aaatcaaaca
    15361 gcacacgagc gacgtcggct gttgtcaatg aagaaccgtc taaagtcacc ataagcccaa
    15421 ctcctttttc tttactttgg taaagcgccc atacaaaaag gagctatgct gtgaacatct
    15481 gttttcacgc atagccccct atcgtctaag atctatgggc tgtttcatat gtgattaatt
    15541 ccaacaccga atgtctcgtg ctcaagacct ttaatcggcg ccccgattgt tccgtaaagc
    15601 gagacagcaa tccaatcgcc ttccgcttca ctttcataag gatttcccct caaaacggca
    15661 aacctcaagc ccaccgtccg aagcagcgat cctagcagca tttcacctct ggtcacgcca
    15721 tgcaaagcct ccatcgtcgc atgataaagc gcatgtgact cccgataacc ctcagattga
    15781 atgacaccgc tctttttgga agcggtttca attgcagcta ctactttatg cgcgtccatt
    15841 gatcctacct tgccaagaca gaccttccat ccgtctcgct ccagctcctc aacctgcgta
    15901 ctctcttccg cctcattcag cagcaggaga acagacagcc gtccgatccg acgctcttta
    15961 tgcagtgtca tatgaatcac tcaattccta aaaattctga taactattaa ctgagtatta
    16021 tattaattgg ttcagcagca gaagtcaaaa ggttttttac agtctttaac aagttagatt
    16081 gctattgtaa tagcgtgacg cagaaagcag cacattgcac acgaataccc agacagaagt
    16141 gcaagcggcc gctgtcatat tgctgacaat gagaggtaaa atgccaaaaa gaggcgaagt
    16201 tgccggagaa aagtcgacga ctttacaaga ccggacaaag cgttcattac gtacgcaaat
    16261 gtagaaacag aagtaattga agaaggagaa acagcaaaag agttgaacta tgaaggagag
    16321 gatatgcaag cagcaagttc tacgcaaaac agacagacat cagtctgact atgtaagaga
    16381 aatctgtttg aatatgaaaa cattcggctg ttttaatagg ccggggtatc ttcatagaga
    16441 aatgtaagcg tttaaaattt aataaaaaag tgaggcgaat tgtttagatg ttcaaccgat
    16501 tgttccgtgt atgttttctt gcagctctta tcatggcctt caccctccca aactccgtct
    16561 atgcacaaaa acctatattt aaagaagtca gcgtccatga cccttccatc attgaaacaa
    16621 gcggcacctt ttatgttttt ggatctcatc tcgcttcagc aaaaacaaat gacctcatgc
    16681 aatggcagca gctgaccacc agcgtaagca acgacaaccc acttatcccg aatgtctata
    16741 aagaattaaa agataccttc gaatgggcgc aatccgatac tctttgggcg gctgacgtca
    16801 cgcagctggc ggacggcaaa tactacatgt actacaacgc ctgccgcggc gactcaccta
    16861 ggtccgccat gggtgttgcc gtcgctgaca acatcgaagg gccatacaaa aacaaaggca
    16921 tctttttgaa atcaggaatg gaaggcacaa gcagcgatgg aacaccgtat gacgcaacca
    16981 aacatccgaa tgtcgtcgac ccgcatacct tctttgataa agacggaaag ctgtggatgg
    17041 tgtacggatc atactcaggc ggcattttca tacttgaaat gaatccgaaa acgggcttcc
    17101 cgcttcctgg gcagggctac ggcaaaaaac tgctcggcgg caaccacagc agaatcgaag
    17161 gcccgtatgt tctctacaat ccagacaccc aatactacta cttataccta tcatatggcg
    17221 gtctcgatgc aacaggcggc tataacattc gtgtggcccg ctccaagaaa ccagacggcc
    17281 cttactatga tgcagaaggc aatccaatgc ttgatgtccg cggcaaagaa ggcacattct
    17341 tcgacgaccg ttccatcgaa ccatacggcg tcaaactcat gggcagctac acttttgaaa
    17401 cagaaaatga aaaaggcacc gggtacgtct caccaggcca caactccgca tactatgatg
    17461 aaaaaaccgg gcgttcctat ttaatcttcc acacccgctt cccgggcagg ggtgaagaac
    17521 acgaagtcag agtccaccaa ttgttcatga acaaagacgg ctggccggta gcaacgccat
    17581 atcgttatgc gggcgaaaca ctgaaagaag taaaacaaaa agatatcaca ggaacataca
    17641 aactcatcca gcacggaaaa gacatctcag ccgacatcaa acaaaccatc aacatccagc
    17701 tcaacaaaaa ccacaccatt tccggggaaa tgaccggaac atgggagaaa accggaaaaa
    17761 ataccgctaa catcacgtta gctggcaaga agtataacgg ggtattttta cgccagtggg
    17821 attcggtgag agagaagaac gtcatgacgt ttagtgtgtt gaatggcaac ggtgaggctg
    17881 tttggggatc taaataagat ggagaagcgc cttcgtagga aggcgttttt ttatgagttt
    17941 tattgactat aagaaacagt taagtgggag aaaaaataaa aatgaaagag agattaaaga
    18001 cttaaataaa aagtccctcc tatgattatt ttctccctct cataaggtga ttagatctat
    18061 ttttagcatt ttagaaccag ttaaacacct ctcaagacaa acctttttac ctatttatcc
    18121 aatatgatcc atcatgtaat atgaaaatag tctgtattgt aaagaattta cacagtttga
    18181 tagaaacacg aggtgttgcg gcatgcatag tgaaatgttg ttacattcgg taaaagccga
    18241 cttacatgaa aagcaggaac agatccatca attaaaacga gtgctgcacg aaatcaggca
    18301 aatcaaacac gaattctccg aggcccagca tctcattcac tggcctcatc ttaaccggga
    18361 ggcatggaga ggaacacatg cggagcggtt tgaagatatt cgtgaaggaa tgaacaaagc
    18421 atatcatcaa attaaaagcg aacaggtcag cggaatcatc gaaagcatag aaggaaaaat
    18481 cgattcatta gagggcgatg tctattccat aagacgccaa attacgagga tagagcatga
    18541 aatagagaat gaaaaacata aaaagtgagg tgagcacaaa tggcacagga aattaaaatg
    18601 gtgtatggca cagtgaagca aggactttct cagctcaaga attcagctga actcaagtcc
    18661 tccttgcccg gccatctctc agggcgaaac catttgaatg tggtaaagtc catcgagcaa
    18721 ttaaatgagg acatcaaaga gctcactgaa gcatatgcgt ccgttctggc caagcatatc
    18781 gcacaaacgg aaagcgcggt aaacgccatg aaggaaacgg acgaaaacat atcatcttcc
    18841 atgaaataaa gcgcgggagg acaagggatt gaaaacatta gatgtccacg ctcttcacga
    18901 gggcattcag catacgattg agaaactgga caagcaaaaa caacagctgg aaaagctgga
    18961 aaaaagcgtt gagcatctgg caggcatgaa ggatgcgctg aaaggaaaag gcggagatgc
    19021 catccggacc ttttacgagg agtgccacaa gccttttctc cttttctttg gcatgtttat
    19081 cgacgaatac aaaaaagtgc tgaaacaaac acagcatgcg atttcctctg tagaatctga
    19141 ctcccacggc atgatcgcag aggcttttct ctcacacgat gcgagacatg gggtcaagca
    19201 tgcacgagaa gtgacagagc agctcactga cgcagtcaat cgccagacat cagccatcgg
    19261 ccacatcgtc agcttgccgg cagtcaatga tatctttttc cgaatggaaa cagaacaggc
    19321 tgagcggctg atttcagaca ccctgaataa gctctttcaa tttgacggcc agcaaaccca
    19381 agcactagaa accgcaaaat cagattttca aacgatgaaa aaatacatgg atcagctcgg
    19441 aaccatgtat accggtccga aaattgaaat tacgggctac aaaagcggct ctatcctgaa
    19501 atcacaggaa gaagaaaaca tcaaccaaac cttcggcgcg attaacccgc aaatgaagca
    19561 ggcggatgat tctccgatgg agatgatgtt gaagaaatta gccgagaatg aaaagtctaa
    19621 agtggattca gttgtcaaaa cgggtgattc taaaaaggta agtaaaaata tcatcgttat
    19681 caatggtaaa gtgtataata cgagtgaaca tagagaacat ataaaaactg atttctcaaa
    19741 tgcagaggtt aagcaagtcg tttataatga tacactttac aatgtataca tatctggtaa
    19801 tgacatgaag cttgaacctg tcgtctcgct ttcggacatt aaagtggatg agaatggata
    19861 tgtgaaaatt ttagagacag ctgtagagtt ttcaggtata aatgatctgt ttagagctgc
    19921 tacaggcaga gatcctataa caggcgaaaa agtctcgagt aaagatcgga ttgttgcaac
    19981 tgttcacgcg gtaccaattt cgaaaatagc taagttgcaa aaatttaata tatataagtt
    20041 aattaatggt gagaaaaaga cgaagaaggc ttctaagatt gaaaaaggta caaagaaaaa
    20101 taaaaatgac aaggtactaa ctaaaaatgg agcctttaga gatgccaaaa ggagagcagg
    20161 aatacctaac tcttctcaac ataagaagcc agtagacgtt tttgatggaa caagtgagaa
    20221 tagaagggta tatgaatttg aagtagatgg caagaaaaaa tatattatag agcatagaga
    20281 agacaaactt ggtcgggggc cccactttca cggtgctgat gatttaaaag gtaatccgct
    20341 agaaaaagga agatataatc agtatcctgg tcactcacca gaggattttg aaggttataa
    20401 aaataaagga aagtttaaga aaaaaggtga ttaaaacttg aataacgaga gagttaaaaa
    20461 gatggaactt ctaaaaagga aaagtagaag aaaaaattta attagagaat tagatttctt
    20521 acatataact gaggattcct ttttagatat tgaagaaaac gagctgttct gcaaaaaagc
    20581 attttcaatt cttgacacaa agcagaataa agtacaaata caaggtactg attatataga
    20641 gaatattcaa aaatctattc aattattaaa ggatactttt gagaatgtgg aattgggttc
    20701 aaatgaagca aggctacttt tttttaggga aaatgaaata gaggctgttt tattatcttt
    20761 agacgaaata tttataaatt tggacaaagt gcttgaaatc acaaaatttt caattggata
    20821 tggagatttt attcttacat cagaagattt caaattcgga ttatgtatag aacggacaga
    20881 atatcactat gaattttgtg tctggggatt atcagaaaaa aacaaaaaat gacattagtc
    20941 tttcaaggct tttatatatc gagccataga ctaaagaaat cggacttttg agtttaaggt
    21001 gataatagag agtgaagaag atagatgaga aatttttatt gagaaaaata aatgaatcat
    21061 tattaatcat ccagattgtt ttccccctag caggaatagt tctaactatc atgacaatct
    21121 ggttagcaaa tgccaatcaa gttcacgata tagagttata tgtgattgct ggtttatcat
    21181 atggtatatt tttctttgtg ttccctttag gtatttatat attcaggaaa agagtactta
    21241 taaaaaaaat taaatgatat agacggatat aaatagagtt tctaaagtgg catacactta
    21301 aagaaccatt gatcttctat aatttattag atgatgaatg atttaaacat ttaccataaa
    21361 atgaaatatc tatataggat attaatccta ttatttttcc ctaaaagaag cgaaatgata
    21421 tgttatcgat caataagcaa gatgacccgg tttttcagtt tttagctgga acattccatc
    21481 aagatattga aactcctgat gacgctatac aagagttatt aacagaggaa agtaaagaat
    21541 atttggagga tgctattgtc tttttaacgg attttattga aagtgagcat tcagaaaatg
    21601 agaaaaacga ttacattcaa tcttgcgcag atggcgtgta ttttcctgcg tttaatttag
    21661 aaccaataga ttggctaaag aatgtaatag tgcagataaa gaagccttta aataaaatct
    21721 aaacggtaac aattcataac cttgattgga aaaaatgcct ttcaaggttt ttaattacaa
    21781 taatttttta ttgaagttaa tactaagttc aaatctttat gattactttt gttctagaaa
    21841 cgatagtcaa caccaaaaat gaaagcgttg acatcccttg aatctagtgc taaagtatac
    21901 ctacaaacaa ataaaacgac ccgtcaggat tgttactgcg aaagcaggca aaacctaaat
    21961 ggtgcaggtg caggaggaga ctctcgcaat ctgtgtcatt taggtttttt ttattctctt
    22021 ttaggaggtg atgcggcatt gatacaaaaa aagctggtga aaggcggcca cctttcttcc
    22081 agcagtcccc ccataaaaag gaggtataca catggattat gataaattat cgaaggacat
    22141 attacaactc gtaggcggtg aagacaacgt tcagtgcgtg atccactgta tgacgaggct
    22201 gcgttttaat cttcatgaca attcgaaggc ggatcgcagt cagttggagc agctgcctgg
    22261 agtgatgggc accaatatca gcggcgagca gtttcaaatc attatcggaa acgatgtgcc
    22321 gaaggtgtat caggcgattg tgcggcacag caatctcagt gatgaaaaga gcgctggttc
    22381 atcctctcag aaaaagaatg tgctgagtgc ggtctttgat gtgatttctg gggtgtttac
    22441 tccgattctg cctgcgattg cgggagcggg gatgatcaaa gggcttgttg cgctggcagt
    22501 tacgtttggc tggatggcgg agaagagcca ggttcatgtc attttgacgg ctgtcggtga
    22561 cggtgcgttc tacttcctgc cgctcctgct agcgatgagt gcggcgagaa aattcggaag
    22621 caatccgtac gtagcggctg ccattgcggc ggcgatcctg catccggatt tgacagccct
    22681 gctcgatgcg gggaaaccga tttcctttat tgggcttcct gtaaccgctg ccacttattc
    22741 gtcaacggtc atcccgattt tgctggcgat ttggattgct tcatacgtgg aaaaatggat
    22801 tgaccgtttt acacacgcat ctctcaaatt gattgtggtt ccgacattca cgctattgat
    22861 tgtcgtgccg ctgacattga ttacagtcgg tccgcttggc gctattttag gagaatactt
    22921 gtcttctggg gtcaattatt tgtttgatca tgcagggctt gtggcgatgg ttttgctggc
    22981 tggtacattc tctttaatca ttatgacggg catgcactat gcctttgtgc cgatcatgat
    23041 caacaacatc gctcaaaacg gccacgatta tttactgccg gctatgtttt tggcgaatat
    23101 ggggcaggcg ggagcatcat ttgccgtctt ccttcgctcc agaaacaaaa aatttaaatc
    23161 actcgcgctt accacaagca tcacggcgct gatggggatc acagaacctg cgatgtacgg
    23221 cgtgaatatg cgattgaaaa agccgtttgc ggccgctttg attggcggtg cagccggtgg
    23281 cgcgttttac ggcatgacgg gtgttgcttc ctatatcgtc ggggggaatg caggtctccc
    23341 gagcatccct gtctttatcg gcccaacgtt tatttacgcg atgatcggcc ttgtgattgc
    23401 gtttgcggcg ggaacagcag ctgcgtattt gcttggattc gaggatgtgc cttctaacgg
    23461 cagccagcag ccggcagtgc atgaaggcag cagagagatc attcacagcc cgattaaggg
    23521 agaagtgaaa gcattaagtg aagtcaaaga cggagtgttt tctgccggga tcatgggaaa
    23581 aggattcgcc attgagcctg aagaaggaga agttgtgtcg cctgttcgtg gaagcgttac
    23641 caccattttt aaaacaaaac acgcaattgg cattacgagt gatcagggag ctgaaatact
    23701 catacacatt ggattggaca cggtaaagct ggagggacaa tggttcacgg ctcacatcaa
    23761 agaaggcgac aaggtcgcac cgggagatcc gctcgtgtcc tttgatctgg agcaaatcaa
    23821 agccgcggga tatgacgtca ttaccccggt gattgtgacc aacacagacc aatattcgtt
    23881 ttcgccggtg aaagagatcg gtaaagtgca gccaaaagaa gcgctgcttg ctttatcttg
    23941 aaaaaactaa tggggtgatc aatatgagtt caaatgaaaa acgatttcca gaaggatttt
    24001 tatggggcgg cgcagttgct gccaaccaag tggagggtgc ttataacgag ggtggtaagg
    24061 ggctttcgac agctgacgta tcgccgaacg ggatcatgtc tccatttgat gaaacaatga
    24121 cttccttgaa tctgtatcac aacgggattg acttttatca tcgttataaa gaggatatcg
    24181 ccttatttgc agaaatggga tttaaggcgt tccgcacatc gattgcgtgg acgagaattt
    24241 ttccgaatgg cgatgaagag gagcccaatg aagacggcct cagattttat gatgatctgt
    24301 ttgatgagct gttaaagcat catattgagc ctgtcgtaac catctctcat tatgaaatgc
    24361 cgctcggttt agtgaaaaag tatggcggct ggaagaatcg caaagttata gagttttatg
    24421 aacgctatgc caaaacggtt ttcaaacgct atcaacacaa agtgaagtat tggatgacgt
    24481 ttaatgaaat taacgtggtg ctccatgcgc catttaccgg aggcggtctt gtttttgaag
    24541 aaggagaaaa caaattaaac gcgatgtacc aggcggcaca ccaccaattt gtggccagtg
    24601 ctcttgctgt caaagcgggc cacgacatca ttcctgattc gaaaatcggc tgtatgatag
    24661 cggcaacgac aacctatccg atgacttcta agccggagga tgtcttcgcg gcaatggaga
    24721 atgagcgcaa aacacttttc ttctcagatg ttcaggcaag aggcgcatac ccgggatata
    24781 tgaaacgcta tctggcagaa aacaatattg aaattgaagt ggctgaaggc gatgaagagc
    24841 tcttgaaaga acatacggtg gattatattg gatttagcta ctacatgtcg atggctgcga
    24901 gcacagatcc ggaagagctt gcaaaatcag ggggcaacct gctgggcgga gtcaaaaacc
    24961 cttacctcaa atcatcagaa tggggctggc agattgatcc gaaaggcttg cgcatcacgc
    25021 tcaacacctt atacgaccgt tatcagaagc cgctgttcat cgttgaaaac ggccttggcg
    25081 ctgtagacaa ggttgaagag gacggcacga ttcaggacga ttacagaatc aactatctgc
    25141 gtgatcattt aattgaagcg cgcgaagcca ttgcggacgg cgttgaatta atcggataca
    25201 catcatgggg gccaattgac cttgtcagcg catctaccgc ggaaatgaaa aaacgctacg
    25261 gcttcattta tgtggaccgg gacaatgaag gacatggaac atttaaccgt atcaagaaaa
    25321 aaagcttcaa ctggtatcag caggtcatcg ccacaaacgg agagagtctc tgacaatttt
    25381 ttgaaaactc atgcgcttca attgacaata ac
//
