LOCUS       gnlProkkaHONPPGBL_4    22001 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HONPPGBL_4.
ACCESSION   gnlProkkaHONPPGBL_4
VERSION     gnlProkkaHONPPGBL_4
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 19:14:42
            Original ID  :: gnl|Prokka|HONPPGBL_4
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 22001
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..2001)
                     /NRPS_PKS="Domain: Condensation_Starter (3-300). E-value:
                     4.5e-92. Score: 300.4. Matches aSDomain:
                     nrpspksdomains_ctg4_1_Condensation_Starter.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     238.1; E-value: 3.5e-72)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_1"
                     /sec_met_domain="Condensation (E-value: 9e-76, bitscore:
                     250.5, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.3e-46, bitscore:
                     154.7, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEHTYSLTHAQRRVWFTELLEPDTSICNLTACVKFKGNIELDTL
                     EGALNHSISRNDAIRFQLLEGEELEPRLHLTEYKYYPLRIIDFSNVEMIEIEQWIQDQA
                     SIPFKLFNSPLYQFYLLRIDSHEVWLFAKFHHIIIDGISLNVMGNQIIDLYQKMKKKDP
                     LPDQPEPSYLSYIEKESQYLQSPRFAKDRLFWTQTFEHPLEYHSLADQTSLQKQSTSAS
                     RDTIILSPDLEQTIRIFCEEHKINIISLFMASFYICISRITSKKDLAIGTYYGNRGSKA
                     EKEMLGMFVSSLPIRITVDPDTDFLSFVRTIGREQLSVMRHQRFPYNLLVNELRNEQKD
                     LHNLIGISMQYQPLQWHNADDFDYETALYFSGYTANELSVQIQERIDNGTIQLNFDYQN
                     ILFSLEDIKRIQSHLLTILENALKHPHSFIRELDMTNTREKQKLLYEFNKTEAVSPKAF
                     TLHGLFERQAAFTPERLAIRFSGGSLTYAELDMYASRLAAHLAARGVTNESIVGVLSER
                     SPDMLIAVLAVLKAGGAYLPLDPAYPKERLSYMLKDSGASLLLTQPGCSAPNFSGEMLE
                     VDMTSLEREEVKRYVSASVSDGSLAYVIYTSGSTGQPKGVAVEHRQAVSFLTGMQYQFP
                     LSEDDIVMVKTSFSFDASVWQLFWWALSGASA"
     protocluster    1..22001
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[0:2001]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..2001
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..22001
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22001
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS_motif       complement(142..201)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0007"
                     /evalue="2.60E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg4_1"
                     /protein_end="620"
                     /protein_start="600"
                     /score="35.2"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGQPKGVAVEH"
     CDS_motif       complement(385..426)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0006"
                     /evalue="3.90E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg4_1"
                     /protein_end="539"
                     /protein_start="525"
                     /score="19.9"
                     /tool="antismash"
                     /translation="LAVLKAGGAYLPLD"
     CDS_motif       complement(949..1062)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0005"
                     /evalue="3.10E-09"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="ctg4_1"
                     /protein_end="351"
                     /protein_start="313"
                     /score="29.4"
                     /tool="antismash"
                     /translation="REQLSVMRHQRFPYNLLVNELRNEQKDLHNLIGISMQY"
     aSDomain        complement(1102..1992)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_1_Condensation_Starter.1"
                     /domain_subtypes="Condensation_Starter"
                     /evalue="4.50E-92"
                     /label="ctg4_1_Condensation_Starter.1"
                     /locus_tag="ctg4_1"
                     /protein_end="300"
                     /protein_start="3"
                     /score="300.4"
                     /tool="antismash"
                     /translation="HTYSLTHAQRRVWFTELLEPDTSICNLTACVKFKGNIELDTLEGA
                     LNHSISRNDAIRFQLLEGEELEPRLHLTEYKYYPLRIIDFSNVEMIEIEQWIQDQASIP
                     FKLFNSPLYQFYLLRIDSHEVWLFAKFHHIIIDGISLNVMGNQIIDLYQKMKKKDPLPD
                     QPEPSYLSYIEKESQYLQSPRFAKDRLFWTQTFEHPLEYHSLADQTSLQKQSTSASRDT
                     IILSPDLEQTIRIFCEEHKINIISLFMASFYICISRITSKKDLAIGTYYGNRGSKAEKE
                     MLGMFVSSLPIRITVD"
     CDS_motif       complement(1114..1203)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0004"
                     /evalue="8.20E-09"
                     /label="C5_starter_265-294"
                     /locus_tag="ctg4_1"
                     /protein_end="296"
                     /protein_start="266"
                     /score="27.9"
                     /tool="antismash"
                     /translation="DLAIGTYYGNRGSKAEKEMLGMFVSSLPIR"
     CDS_motif       complement(1537..1602)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0003"
                     /evalue="2.40E-07"
                     /label="C3_starter_134-155"
                     /locus_tag="ctg4_1"
                     /protein_end="155"
                     /protein_start="133"
                     /score="23.6"
                     /tool="antismash"
                     /translation="FHHIIIDGISLNVMGNQIIDLY"
     CDS_motif       complement(1807..1923)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0002"
                     /evalue="1.60E-08"
                     /label="C2_starter_024-063"
                     /locus_tag="ctg4_1"
                     /protein_end="65"
                     /protein_start="26"
                     /score="27.1"
                     /tool="antismash"
                     /translation="ICNLTACVKFKGNIELDTLEGALNHSISRNDAIRFQLLE"
     CDS_motif       complement(1948..1986)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0001"
                     /evalue="3.80E-03"
                     /label="C1_starter_004-017"
                     /locus_tag="ctg4_1"
                     /protein_end="18"
                     /protein_start="5"
                     /score="10.2"
                     /tool="antismash"
                     /translation="YSLTHAQRRVWFT"
     CDS             complement(2376..3851)
                     /locus_tag="ctg4_2"
                     /transl_table=11
                     /translation="MKKSIKLYVAVLLLFVVASVPYMHQAALAAEKQDALSGQIDKILA
                     DHPALEGAMAGITVRSAETGAVLYEHSGDTRMRPASSLKLLTAAAALSVLGENYSFTTE
                     VRTDGTLKGKKLNGNLYLKGKGDPTLLPSDFDKMAEKLKHSGVKVIKGNLIGDDTWHDD
                     MRLSPDMPWSDEYTYYGAPISALTASPNEDYDAGTVIVEVTPNQKEGEEPAVSVSPKTD
                     YITIKNDAETTAAGSEKDLTIEREHGTNTITIEGSVPVDANKTKEWISVWEPAGYALDL
                     FKQSLKKQGITVKGDIKTGEAPSSSDVLLSHRSMPLSKLFVPFMKLSNNGHAEVLVKEM
                     GKVKKGEGSWEKGLEVLNSTLPEFGVDSKSLVLRDGSGISHIDAVSSDQLSQLLYDIQD
                     QSWFSAYLNSLPVAGNPDRMVGGTLRNRMKDTPAQGKVRAKTGSLSTVSSLSGYAETKS
                     GKKLVFSILLNGLIDEEDGKDIEDQIAVILANQ"
     CDS             complement(3885..4862)
                     /locus_tag="ctg4_3"
                     /transl_table=11
                     /translation="MANFIEKITYLGTPAIKAGNEYLEMIVVPEWGSNVISLVDKTTKV
                     QLLREPETAESFHDTPTLYGIPILFPPNRISDGTFSFRGRTYHFDINEKDKHNHLHGFL
                     YHEKWNVVTAKKTDEEVIVETEIDLSELPHVYKQFPHHAVVRMTYTVKGNTLFKHATVM
                     NKGKEAFPWGIGYHTTFVFPAESSLFSLTADQQWELDERLLPTGKLMDVPNKEALHEGM
                     DLRHKQLDDVFLSSYQKRGGENQAVIYHQHAHISIIYKADEQFKHWVVYNADGKQGYLC
                     PEPYTWVTNAVNLDLPSSLTGLQVLEPGEETTAKSSITIELNHQ"
     CDS             complement(4996..6387)
                     /gene_functions="transport (smcogs) SMCOG1086:MATE efflux
                     family protein (Score: 397.1; E-value: 1.5e-120)"
                     /gene_kind="transport"
                     /locus_tag="ctg4_4"
                     /transl_table=11
                     /translation="METSQEPLVTQKKSKPSVWRSMSLFLVPLLLSNVLQSVGQLVGMM
                     AVGRWLGVDAVAAVSSFFPLFFLLISFTIGIGSGSSILIGQAYGAKNEERLKAVVGTTL
                     TFTFLLGVVLAVIGSIFTLDILRLMGTPENVIHVSANYARILFYAMPFMFLYFAYTTFL
                     RGTGDSKTPFYTLIVSTVINIALLPVLILGMFGFPKLGIYGSAYATVISTIATFLVLMV
                     YLRKRKHPLQFDKTVRRYLKMDKELLVLLLRLGVPASINMILVSLSEIAVISFVNHYGS
                     NATAAYGVVNQVASYVQMPAVSLGIAVSIFAAQSIGANEFDRLKQVIRVGIWLNYIIGG
                     VLIILIYVFSHQILSLFLTEQETLYIAHRLLMITLWSYLLFGNAQIISATMRASGTVLW
                     PTVISIFAIWGVEVPVAFVLSHYTKLEILGVWVGYPAAFAVSLLLIYGYYQFVWKKKQI
                     TRLIQ"
     CDS             6673..7218
                     /locus_tag="ctg4_5"
                     /transl_table=11
                     /translation="MKKCLLFLTTIALILSLSTNAFAKNTSGDLSQKQALQLALSAREH
                     FWNTMSGHNPKVKKAVCPSGTFEYQNLQYVYMCSDLGTKAKAVNYLTPIFTKTAIEKGF
                     KDYHFTVSKGKLAVPIGDGDNLLNWKKSTAKLVSKKGGTITYEFTVPTLDGSPSAKRKV
                     TFVKENKKWKVNQFDAVI"
     CDS             complement(7437..7982)
                     /gene_functions="other (smcogs) SMCOG1077:phage integrase
                     family protein (Score: 120.2; E-value: 2.5e-36)"
                     /gene_kind="other"
                     /locus_tag="ctg4_6"
                     /transl_table=11
                     /translation="MHIVQPIRSLEKIQEVKQYLLNKNKRDYFLFIFGINSALRISDIL
                     PLQVKDVQNKDHLWATESKTKKKRKILILESLKQEIYEYTKDMKENEYLFKSVRTRKPI
                     SRIQAYRILREAAAACGLEEIGTHTLRKTFGYHFYQRTKDIAELQRILNHSSPSITMRY
                     IGIDEDTTRAAYKVFGGL"
     CDS             complement(8300..8530)
                     /locus_tag="ctg4_7"
                     /transl_table=11
                     /translation="MYLTIEETAEYTNLSEDYIKSLVLEGKIRAVHDGEQFLIYKEQFK
                     THLEQLENYKALVQEILNEPIPEDIDVKDED"
     CDS             8715..10478
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1274:gamma-glutamyltranspeptidase (Score: 657.4;
                     E-value: 2.7e-199)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_8"
                     /transl_table=11
                     /translation="MKRTWNVCLTALLSVLLVAGSVPFHAEAKKPPKSYDEYKQVDVGK
                     DGMVATAHPLASEIGADVLKKGGNAIDAAVAIQFALNVTEPMMSGIGGGGFMMVYDGKT
                     KDTTIIDSRERAPAGATPDMFLDENGKAIPFSERVTKGTAVGVPGTLKGLEEALDKWGT
                     RSMKQLITPSIKLAEKGFPIDSVLADAISDYQEKLSRTAAKDVFLPNGEPLKEGDTLIQ
                     KDLAKTFKLIRSKGTNAFYKGKFAKTLSDTVQDFGGSMTEKDLENYDITIDEPIWGDYQ
                     GYQIATTPPPSSGGIFLLQMLKILDDFNLSQYDVRSWEKYQLLAETMHLSYADRASYAG
                     DPEFVNVPLKGLLHPDYIKERQQLINLDQVNKKPKAGDPWKYQEGSANYKQVEQPKDKV
                     EGQTTHFTVADRWGNVVSYTTTIEQLFGTGIMVPDYGVILNNELTDFDAIPGGANEVQP
                     NKRPLSSMTPTILFKDDKPVLTVGSPGGATIISSVLQTILYHIEYGMELKAAVEEPRIY
                     TNSMSSYRYEDGVPKDVLSKLNGMGHKFGTSPVDIGNVQSISIDHENGTFKGVADSSRN
                     GAAIGINLKRK"
     CDS             complement(10603..11460)
                     /gene_functions="regulatory (smcogs) SMCOG1014:LysR family
                     transcriptional regulator (Score: 191.9; E-value: 2.4e-58)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg4_9"
                     /transl_table=11
                     /translation="MESGDLKIFQAVAREGSITKAAQMLNYVQSNVTARVHNLEEDLNI
                     RLFHRTNRGMKLTAAGENLLQYADQVLSLLDKAEKSTRMSRQPKGPLRIGSLETTAVTH
                     LPEHAASFLRRFPEVDLSVNTADTHHLIQQVLDHKVDGAFVYGPVEHAAVRQLHVSHDE
                     LVLISSREETAEDMLQQPMLFFGAGCSHRDRVKRLLEEAGLHNPKIIEFGTLEAIIKGV
                     SAGMGTALLPKSAVDGSEHRTNVWIHKLPPAYKDLEIVFIHRKDFFITSAFQTFLDEIN
                     EMKR"
     CDS             11589..12578
                     /NRPS_PKS="Domain: PKS_ER (11-324). E-value: 4.7e-39.
                     Score: 126.2. Matches aSDomain:
                     nrpspksdomains_ctg4_10_PKS_ER.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase
                     (Score: 244.8; E-value: 2e-74)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_10"
                     /sec_met_domain="ADH_N (E-value: 8.6e-13, bitscore: 43.9,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 3.6e-27, bitscore:
                     90.7, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAVIHNGKAGLQGLSVEDVPSTKPGYGEVKVKLKSAGLNHRDLF
                     LMKNKSEQDPHMILGSDGAGIIEEIGEGVKNVTVQTEVVIFPTLNWDLTENVPPVPEIL
                     GGPSDGTLAEYVIIPSQNAIKKPAYLSWEEAGVLPLSALTAYRALFTKGQLKKGEHLLI
                     PGIGSGVATYALFMAKAIEATVSVTSRSEEKRKKALQLGADYAFDSYSNWDEQLQGKKA
                     DVVLDSIGPALFSEYFRHVKPNGRIVSFGASSGDNLSFPVRSLFFPQVNVLGTSMGSGE
                     EFQAMLAFIDKHKLRPVIDRIYPLEKACEAYKRMQEGRQFGNIGIVME"
     aSDomain        11622..12560
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_10_PKS_ER.1"
                     /evalue="4.70E-39"
                     /label="ctg4_10_PKS_ER.1"
                     /locus_tag="ctg4_10"
                     /protein_end="324"
                     /protein_start="11"
                     /score="126.2"
                     /tool="antismash"
                     /translation="LQGLSVEDVPSTKPGYGEVKVKLKSAGLNHRDLFLMKNKSEQDPH
                     MILGSDGAGIIEEIGEGVKNVTVQTEVVIFPTLNWDLTENVPPVPEILGGPSDGTLAEY
                     VIIPSQNAIKKPAYLSWEEAGVLPLSALTAYRALFTKGQLKKGEHLLIPGIGSGVATYA
                     LFMAKAIEATVSVTSRSEEKRKKALQLGADYAFDSYSNWDEQLQGKKADVVLDSIGPAL
                     FSEYFRHVKPNGRIVSFGASSGDNLSFPVRSLFFPQVNVLGTSMGSGEEFQAMLAFIDK
                     HKLRPVIDRIYPLEKACEAYKRMQEGRQFGNI"
     CDS             complement(12635..14116)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="other (smcogs) SMCOG1285:ferredoxin fdxC
                     (Score: 57.7; E-value: 1.6e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_11"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.1e-27, bitscore:
                     91.8, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKPTGFMEIKREKPAERDPLTRLKDWKEYSAPFSEEASKRQGAR
                     CMDCGTPFCQIGADINGFTSGCPIYNLIPEWNDLVYRGRWKEALERLLKTNNFPEFTGR
                     VCPAPCEGSCTLAISDPAVSIKNIERTIIDKGFENGWIQPRIPKKRTGKKVAIVGSGPA
                     GLASADQLNQAGHSVTVFERSDRAGGLLTYGIPNMKLEKGIVERRIKLLTQEGIDFVTN
                     TEIGVDITADELKEQFDAVILCTGAQKQRDLLIEGRDSKGVHYAMDYLTLATKSYLDSN
                     FKDKQFIDAKGKDVIVIGGGDTGADCVATALRQKAKSVHQFGKHPKLPPARTNDNMWPE
                     QPHVFTLEYAYEEAEAKFGRDPREYSIQTTKMVADKNGKLKELHTIQMEKVKNEHGKYE
                     FRELPGTEKVWPAQLVFIAIGFEGTEQPLLKQFGVDSVNNKISAAYGDYQTNIDGVFAA
                     GDARRGQSLIVWAINEGREVAREVDRYLMGSSVLP"
     CDS             complement(14133..18695)
                     /locus_tag="ctg4_12"
                     /transl_table=11
                     /translation="MTYNQMPKAQGLYRPEFEHDACGIGLYAHLKGKQTHDIVKQGLKM
                     LCQLDHRGGQGSDPDTGDGAGLLVQIPDAFFRKECKDINLPEKERYGVGMVFFSQKEDE
                     RKKIEKQINALIEQEGQVVLGWRTVPVNVGKIGTVAQKSCPFVRQVFIGASSDLKDNLS
                     FERKLYVIRKQAENWGVTEGLDFYFASLSSQTIVYKGLLTPEQVDAFYSDLQDEAFVSA
                     FALVHSRFSTNTFPTWERAHPNRYLVHNGEINTLRGNINWMRAREQQFVSESFGEDLNK
                     ILPILNADGSDSSILDNAFEFFVMAGRKPAHTAMMLIPEPWTENTHMSKEKRAFYEYHS
                     SLMEPWDGPTAISFTDGKQIGAILDRNGLRPARYYVTKDDYIIFSSEVGVIEVEQENVL
                     YKNRLEPGKMLLIDLEEGRIISDEEVKTQIATEYPYQKWLEEELVQVNPDPESREEEQF
                     SDLLTRQKAFGYTYEDIQKYLIPVIKEGKDPLGSMGNDAPLAVLSDRAQSLFNYFKQLF
                     AQVTNPPIDAIREQLVTSTMTWLGAEGDLLHPSERNVRRIKLYTPVLSNEQFYALKTIV
                     HPDLKSQKIDVLFSEDLERGLKDMFTQAEKAISQGVSLLILSDKKMNERLTPIPPLLAV
                     SGLHQHLIRKGLRTKVSIIVESGEAREVHHFAALIGYGADAINPYLAYATYKQEIDEGR
                     LDISYEEAVSKYGKSITEGVVKVMSKMGISTVQSYRGAQIFEAVGISRDVIDRYFTGTA
                     SQLGGIDLQTIAEEAQRRHREAYQDDYSKTLEPGSDFQWRNGGEHHAFNPKTIHTLQWA
                     CRRNDYNLFKQYTKAADEERIGFLRNLFAFDGNHKPLKLEEVESAESIVKRFKTGAMSF
                     GSLSKEAHEALAIAMNRLGGKSNSGEGGEDPKRFVPDENGDDRRSAIKQIASGRFGVKS
                     HYLVNADELQIKMAQGAKPGEGGQLPGNKVYPWVADVRGSTPGVGLISPPPHHDIYSIE
                     DLAQLIHDLKNANRDARISVKLVSKAGVGTIAAGVAKATADVIVISGYDGGTGASPKTS
                     IKHTGLPWELGLAEAHQTLMLNGLRDRVVLETDGKLMTGRDVVMAALLGAEEFGFATAP
                     LVVLGCVMMRACHLDTCPVGVATQNPELRKKFMGDPDHIVNYMLFIAEEVREYMAALGF
                     KTFDEMIGRTDVLHVSERAKGHWKAGQLDLSTLLYQPEGVRTFQSPQNHKIDQSLDITT
                     ILPAVQEAIESGKEADISIEINNTNRVAGTITGSEISKRYGDEGLPEDTIKLQFTGSAG
                     QSFGAFVPKGMTLYLDGDSNDYVGKGLSGGKIIVKSPEGFNSASDDNVIIGNVAFYGAT
                     SGEAYINGRAGERFAVRNSGVNVVVEGIGDHGCEYMTGGSVVVLGEVGKNFAAGMSGGI
                     AYVLAEDVKAFKRKCNLEMILFESLEDEKEIQQIKAMLERHTAYTNSQKAEDLLDQWED
                     SVKKFVKVIPKNYKQMLASIQEQKAAGLSDEEAIMFAFEANTKPKQNTAASGQKQAVVQ
                     "
     CDS             18842..19744
                     /gene_functions="regulatory (smcogs) SMCOG1014:LysR family
                     transcriptional regulator (Score: 238.9; E-value: 1.1e-72)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg4_13"
                     /transl_table=11
                     /translation="MELRQLRYFMEVAEREHVSEAADHLHVAQSAISRQIANLEEELNV
                     TLFEREGRNIKLTPIGKEFLIHVKTAMKAIDYAKEQIDEYLDPHRGTVKIGFPTSLASQ
                     LLPTVISAFKEEYPHVEFLLRQGSYKFLIEAVRNRDIDLALLGPVPTNFSDITGKILFT
                     EKIYALVPLNHPLAKQKTVHLIDLRNDQFVLFPEGFVLREMAIDTCKQAGFAPLVSTEG
                     EDLDAIKGLVSAGMGVTLLPESTFAETTPRFTVKIPIEFPQVKRTVGIIKPKNRELAPS
                     ANDFYEFVIQFFSKLEQYQ"
     CDS             complement(19796..20911)
                     /locus_tag="ctg4_14"
                     /transl_table=11
                     /translation="MTPDTSMKRVVVKIGSSSLTSIHGEISIRKLEALVDQVVKLKDAG
                     YEVILVSSGAVAAGYRKLGFIQRPEKLPEKQASASIGQGLLMEAYSKLFLAHGYVASQI
                     LITRSDFSDEYRYNNVRNTMNVLLERGIIPIINENDTVTVNRLKFGDNDTLAAKVAGLI
                     DADMLVILSDIDGLYDGNPRTNPEAKRIQRVSEITPDIEACAGDTGSIVGTGGMRSKLD
                     AFKIVMASGIKGFLGQADAGDILYHAVHEQAEGTYFEAEGTLPLNQKEQWIAFNSGPEG
                     EMILSDDCSRKITNGQSSLYLDGVQKIKGKFKSGSVVRLMDSKGMEIGLGIVNYSSVHL
                     QEPEKKKELTNRALIDQEAFVCHVDLSLPVN"
     CDS             complement(20908..21723)
                     /locus_tag="ctg4_15"
                     /transl_table=11
                     /translation="MAEGMISGIVRANKIPKQNICVTNRSNTERLTELELQYGIKGALP
                     NQLCIEDMDVLILAMKPKDAENALSSLKSRIQPQQLILSVLAGITTSFIEQSLLNEQPV
                     VRVMPNTSSMIGASATAIALGKYVSEDLKKLAEALLGCMGEVYTIQENQMDIFTGIAGS
                     GPAYFYYLMEFIEKTGEEAGLDKQLSRSIGAQTLLGAAKMLMETGEHPEILRDNITSPN
                     GTTAAGLQALKRSGGGEAISQAIKHAAKRSKEISEDIEKTAAPLSGVIK"
ORIGIN
        1 cgccgaagca ccggaaagag cccaccaaaa cagctgccac acagacgcat caaaggaaaa
       61 agaggttttc accatgacaa tgtcatcttc cgaaagcgga aactggtact gcatgccggt
      121 cagaaaagaa acagcctggc ggtgctcaac agctacccct tttggctgcc cggtggatcc
      181 cgacgtataa atgacatagg cgagagatcc gtcgctaaca gaagcagaca cataacgttt
      241 tacttcttca cgctcaagag atgtcatgtc cacttcaagc atttcgccag aaaagttcgg
      301 tgcggagcat cccggttgtg tcagcaagag cgatgccccg ctgtctttca gcatgtagct
      361 cagccgctcc tttggatacg caggatcaag cggcaaatac gccccgccgg ccttcaagac
      421 agcaaggaca gcgatcagca tgtcaggtga gcgttcagac aggacaccga cgatactttc
      481 gtttgtgacg ccgcgtgccg caaggtgcgc agccagtcgg ctggcgtaca tatcaagctc
      541 agcgtatgtc agcgaaccgc ctgaaaagcg aatggccagc cgctccggtg tgaaagctgc
      601 ctgtcgctca aacagcccat gcagggtgaa agctttaggc gaaacagctt ccgtcttgtt
      661 aaactcatac aacaattttt gcttttctct tgtattcgtc atatctaatt ctcttataaa
      721 gctgtgcgga tgtttaaggg cgttttccag tatggtaagc agatgagatt gtattcgttt
      781 aatatcctca agagaaaaca agatattttg atagtcgaaa tttaattgaa tggttccatt
      841 gtctatccgt tcttgtattt gaactgaaag ctcgttcgcg gtgtatccgc tgaaataaag
      901 cgctgtttca tagtcaaaat catctgcatt gtgccactga agtggctgat actgcataga
      961 tataccgata aggttgtgta aatccttctg ttcatttctt aattcattta caagcaaatt
     1021 ataaggaaac cgttgatgac gcataacaga aagctgttcc ctgcctattg tgcggacaaa
     1081 ggaaagaaaa tctgtgtcag gatcaaccgt tattctgatt ggaagagaac taacgaacat
     1141 gccgagcatt tctttttcag cctttgaccc tctgttgcca tagtaggtgc caatggcaag
     1201 atctttttta gaagtgattc ggctgatgca tatgtaaaat gaagccataa ataaggaaat
     1261 gatattgatc ttgtgttctt cgcagaagat tcgaatcgtt tgctctagat caggtgaaag
     1321 aatgatggtg tctctggatg cagatgtgct ctgtttttgt aaggacgtct ggtcggctaa
     1381 cgagtggtat tccaacgggt gctcaaaggt ttgcgtccaa aataaacggt cctttgcaaa
     1441 ccgcggagat tgtagatatt gactctcttt ttcgatgtag ctcaagtaag aaggttccgg
     1501 ctgatcaggt aaaggatctt tctttttcat tttttgataa agatctataa tttgatttcc
     1561 catcacattt aaagagattc catctattat gatatgatgg aatttcgcaa atagccaaac
     1621 ttcatgagag tcaattctaa ggaggtaaaa ttgataaaga ggcgagttga acagtttaaa
     1681 tggaatgctc gcttgatcct gaatccattg ctctatttct atcatttcaa catttgaaaa
     1741 atcaattatt ctaagtggat aatatttata ttcagtaagg tgcaatcgcg gctcaagctc
     1801 ttctccttct aacagctgaa atctaatggc gtcgttgcgg gagatggaat gattcagcgc
     1861 tccctccaga gtatcaagct caatattgcc tttgaatttc acacaggctg tgagattgca
     1921 aatgctggta tctggctcca gcagttcggt aaaccacact ctcctttggg catgggttaa
     1981 agaataagta tgttcgctca acggattccc tccagttctc ataataagag gataagaaaa
     2041 agtagaaaaa agcagaaaaa tgacaataaa agaaattata tgactatata atccatatat
     2101 gcactatatt aacggatatt ttttaaagta caataaaaaa cattaaattt ttataacatt
     2161 tttttgaata tagtattatt tctttatttt tcgtttcttt ttttatcaaa tttccggata
     2221 taaagtgata aaagtattgt tttacataag gtcttataca ctacttttta atcgaactaa
     2281 tttgcttttg tgcatcattc ttctaattat tggaaggttc gacaaagaca gacataaaaa
     2341 aacctgtttt ctcatggaaa acaggtctgc cgctattatt gatttgccaa aatgacagcg
     2401 atttgatcct caatatcttt tccatcctct tcatcaatca atccatttag aagaatagag
     2461 aaaacaagtt tttttccgct ctttgtttct gcgtaccccg atagagagct taccgtactg
     2521 agcgatccgg tttttgctct tacttttcct tgtgcaggag tgtctttcat gcggtttctc
     2581 agcgttccgc ccaccattct gtcaggattc cccgcaacag gtaaagaatt tagataagcc
     2641 gagaaccaac tctgatcctg aatgtcatat aacagctgtg aaagttgatc tgaagataca
     2701 gcatcaatat gtgagattcc tgatccgtcc cttaagacga gtgatttaga atcaacacca
     2761 aattccggaa gcgtactgtt taacacttcg agcccctttt cccagctccc ttctcctttt
     2821 ttcactttcc ccatctcttt tacgagcact tcggcatgtc cgttattact taatttcatg
     2881 aacggcacaa aaagtttcga taaaggcatt gagcgatgag agagcagcac atctgaagaa
     2941 ctaggtgctt cacccgtctt gatgtcccct ttcacagtaa ttccttgttt ttttagtgac
     3001 tgcttaaata aatctaaggc atatccggca ggctcccaga cagaaatcca ttcctttgtc
     3061 ttgtttgcgt caaccggtac gctcccttca attgtaatcg tgtttgttcc atgctctctt
     3121 tcgattgtga ggtctttctc tgaaccggca gcagtcgttt cagcatcgtt ctttatcgtt
     3181 atataatcgg ttttcggaga gacagacacg gcaggctctt ccccttcttt ttgatttggg
     3241 gtgacttcaa caatcacagt gcctgcatca tagtcttcgt ttggagacgc tgttagagcg
     3301 gagattggcg cgccataata tgtgtattca tcgctccaag gcatatcagg tgataatcgc
     3361 atgtcatcat gccacgtatc atcaccgatc agattgcctt taattacttt tacgccggaa
     3421 tgtttcaatt tctcagccat tttgtcaaaa tcagatggta aaagtgtcgg atcgcctttc
     3481 cctttcaaat aaaggttacc attcagcttt ttccctttca gtgttccatc cgtccggacc
     3541 tcggttgtaa aagaatagtt ctcgccaagg acagaaagtg ccgcggccgc tgtcaaaagc
     3601 tttagagaag aggcaggcct cattcgggtg tctcctgaat gttcatatag aacagcacct
     3661 gtttccgcag agcgaacggt gatgccggcc attgcgcctt cgagggcagg atgatcagct
     3721 aaaatcttat cgatctgccc ggaaagtgca tcttgttttt cagcggcaag cgcagcctga
     3781 tgcatataag gcaccgaagc aacgacgaaa agcagtaaaa cagcaacata aagctttatg
     3841 ctttttttca ttaatttccc cgcctctctg cgcttcatca ttggctattg atgattcagt
     3901 tcaatggtga tactgctttt agctgttgtt tcttctcccg gctccagcac ttgtaaacca
     3961 gtgagtgacg aaggtaaatc aagattcact gcgtttgtca cccatgtgta aggttcaggg
     4021 cataaatacc cttgttttcc gtcagcattg tatacaaccc aatgtttaaa ctgttcatct
     4081 gccttataaa taatgctgat atgtgcatgc tgatgataaa tgactgcctg gttttctccg
     4141 cccctcttct gataagaaga taaaaagaca tcatccagct gcttgtggcg caaatccatt
     4201 ccttcatgca aagcttcttt attcggtaca tccatcagtt tcccggtcgg cagcaggcgt
     4261 tcatccaact cccattgctg atctgctgtc agggagaata acgagctttc tgccggaaac
     4321 acaaatgtag tatgataacc aattccccaa ggaaacgctt cctttccttt gttcatgacc
     4381 gtcgcatgtt taaatagagt attccctttt accgtgtatg tcatccgaac gacggcatgg
     4441 tgaggaaatt gcttatacac atgggggagc tcagaaagat caatttctgt ttcaacaatc
     4501 acttcttcat cagttttctt cgcggtcact acgttccact tttcatggta aagaaaccca
     4561 tgaagatggt tgtgtttatc cttctcgttg atatcaaaat gatacgttct gccccggaaa
     4621 ctgaatgtac cgtcacttat gcggttaggc gggaacagga ttggaatgcc atacaatgtt
     4681 ggtgtgtcgt gaaaactttc tgctgtttcc ggttcacgca aaagctggac ttttgttgtt
     4741 ttgtccacga gagaaatgac gttgctcccc cactcaggga caacaatcat ttctagatat
     4801 tcgttgcccg ctttgatggc cggcgttccc aaatacgtga ttttctcaat aaagtttgcc
     4861 atgtttactc aacctctcct tgattcattg ctagtataag aattcaatgt actgtaccat
     4921 atttcctcca ttttatattt tcccctatca aataaaaaaa caccgttcaa acttatgaac
     4981 ggtgtgattc gaaggctatt ggatgagacg tgtgatttgt ttctttttcc agacgaattg
     5041 ataataccca taaatcaaca gcaagctgac ggcaaacgca gctggataac cgacccagac
     5101 gccgagtatt tcaagctttg tatagtgaga aaggacgaaa gcgacaggca cctctactcc
     5161 ccagattgca aaaatactga tgacggtcgg ccataaaacc gttccgcttg cccgcatcgt
     5221 tgcagaaata atttgggcat ttccaaacag caaatagctc cacaatgtaa tcatcaaaag
     5281 acggtgcgca atgtaaagcg tctcttgctc ggttaaaaat aacgataaaa tctgatgtga
     5341 aaaaacatag atcagaatga tcagtacgcc gccaatgata taattcagcc aaatccccac
     5401 gcgaatgacc tgctttaagc ggtcaaactc gttcgctccg atggattgcg cagcgaaaat
     5461 agaaaccgca ataccaaggc tgacggccgg catctgtaca tagctggcca cctggttgac
     5521 cactccgtat gcagctgttg cattagagcc gtaatgattg acgaatgaaa taaccgctat
     5581 ctctgataat gagacaagaa tcatattgat gcttgctggg accccaagac gcagcaggag
     5641 aaccagcagt tccttatcca ttttcaaata acgacgcact gttttatcaa attgcagcgg
     5701 gtgttttcgc tttcgtaaat acaccattaa cacgagaaaa gtcgcaatcg tagaaatgac
     5761 agttgcatat gccgagccgt atatgcccag tttcggaaaa ccaaacatgc caaggattaa
     5821 gacaggcaaa agcgcgatgt tgataaccgt gctcacaatc agcgtataaa acggtgtctt
     5881 ggaatctcct gttccgcgca aaaaggtagt atatgcaaaa tataaaaaca taaacggcat
     5941 agcataaaat aaaatacgtg catagttagc gctgacatga atgacatttt caggcgtacc
     6001 cattaaacga aggatatcca gggtgaaaat actgccgatg acggctaaca caacgcctaa
     6061 taaaaatgta aacgtgagcg tcgtcccgac aacagccttt agccgttcct catttttcgc
     6121 tccgtaagct tgtccgatca gaatcgaact tcctgaaccg atcccaatcg taaatgagat
     6181 taaaagaaaa aataacggga aaaaggatga tacagctgcc actgcatcaa caccgagcca
     6241 tctgcctaca gccatcatcc cgactagctg gccgactgat tgcagcacat tgctcagcag
     6301 aagcggcact aaaaagagtg acatcgaccg ccaaactgat ggtttgcttt tcttttgagt
     6361 tacaagaggt tcttgtgatg tttccatatt aaaggactcc tttatttgaa atcgttttta
     6421 aacatgccct cattttttga caaaaacagg atatgtaaca tgttattatt catcactgca
     6481 catatgaaac ccttcccgat tcttctaatt ttacacatct ttttagctta tgaagaataa
     6541 actagcaagt aatggcgtat tttttgtgag taaaagaata aaaaataatt tatgaaaaag
     6601 tattgtaatc tatccgtaat tattgtaaca tttgtaacat aagagaaaga gattttgaag
     6661 gagagagcga taatgaaaaa atgtcttcta tttctaacaa ccattgcact tattctgtca
     6721 ttaagcacaa atgcatttgc gaaaaataca tcaggcgatt tatcacaaaa acaagcatta
     6781 cagttggcat tatccgctag agaacatttt tggaacacca tgagcggcca caatccgaag
     6841 gtgaaaaaag cagtttgccc atcaggcaca ttcgagtatc aaaatcttca atatgtatac
     6901 atgtgcagtg atctaggcac taaagcaaaa gcggtgaatt acttaactcc tatttttaca
     6961 aaaacagcaa tcgaaaaagg ctttaaagat tatcatttca ctgtttcaaa aggaaagctt
     7021 gctgttccaa tcggtgacgg agacaatctt ttgaattgga aaaaatcaac tgctaaactg
     7081 gtctctaaaa aaggcggcac aatcacatac gaatttaccg tccctacatt agacggatcc
     7141 ccttctgcaa aacggaaagt gacattcgtg aaagaaaata aaaaatggaa agtcaatcaa
     7201 tttgacgcag ttatataaga aaaacgcccg gtataagcgg gcgtttttta tttggtttgc
     7261 ataaagaaag acaacaggcg aaaagtgcct gttgtctttt tgtgaatata acgctctagg
     7321 agagattcga actcccgacc tgcagtttag gaaactgctg cactatccgc tgtgctacta
     7381 gagcttttgg tatttatata gtagctctga tgatcaatat tttcaagcga tttgtattaa
     7441 agccctccaa aaaccttata cgcggctctt gtcgtatctt catcaatacc gatatagcgc
     7501 attgtaattg atggtgatga atgattcagt attctctgca gctcggcgat gtctttcgtt
     7561 cgctgataaa aatgatagcc aaacgttttc cggagtgtat gcgtccctat ctcctcaagt
     7621 ccgcacgccg cagcggcctc tcttaaaatt ctgtaggcct gaatgcggga aatcggcttc
     7681 ctggtccgca ctgatttaaa aagatattcg ttttccttca tgtctttcgt atactcgtat
     7741 atttcctgtt tcagcgattc taaaataaga atctttcttt tctttttcgt tttgctttca
     7801 gtcgcccata aatgatcttt attttgaacg tccttcactt gcagcggcag aatatcagaa
     7861 atgcggagcg cgctgttgat gccgaaaata aacagaaaat aatcccgctt gtttttgtta
     7921 agcaaatact gtttgacttc ttggattttc tctagactgc gaatcggctg tacaatatgc
     7981 atcaaaaaac tccttaaaaa ccgttatgta acgttttgag gtctatgtta ctattatagc
     8041 tgaaaaacgt tgaatgtcaa agtgcggcgg catttatgta acataatata catagtgtta
     8101 cataatcttt taaagtagct tcttcaaacc ttcaccctat aaaataagct ttaaagcctc
     8161 ttataaagct tttaacctct tggatactta tccccctact gatcaccaaa aaacctctta
     8221 aaacgaaatc tgaagctccc aattttctgg agcttccgca aaaaaacata caaaaaaaga
     8281 cacaatttta aattgtgtcc taatcctcat cctttacatc aatatcttcc gggattggtt
     8341 catttaatat ttcctgcaca agtgctttat aattctccag ctgttcgaga tgcgttttga
     8401 actgctcctt ataaatcaaa aattgctccc cgtcatgaac ggctctgatt ttcccttcga
     8461 gcaccaagct tttaatataa tcctctgaaa gatttgtata ttctgctgtt tcttcaatcg
     8521 ttaaatacat atagcagtcc cttcttaatc cgtatgctga ttctaatata gcacatggct
     8581 catatcaata taatcaattt tgcacagaaa aacggcttta tgcactatat aatataccat
     8641 ttgtcacttg tgaaaacgct gtaatttttt tacgctaaga ttgtaacaat acagcttcat
     8701 ataggaggga gaacatgaaa agaacgtgga acgtctgttt aacagctctg cttagtgttc
     8761 tgttagtcgc tggaagtgtc ccttttcacg cggaagctaa aaaaccgccc aaaagctacg
     8821 atgagtacaa acaagtagat gttggaaaag acggcatggt tgcgaccgca catcctcttg
     8881 cttctgaaat cggtgctgat gtgctgaaaa aaggaggaaa tgctattgac gcagcggttg
     8941 ccattcaatt tgcactcaat gttacagagc cgatgatgtc aggtattggc ggcggcggtt
     9001 ttatgatggt gtatgacgga aaaacgaagg atacaacgat aatcgacagc cgtgagcgtg
     9061 ctccagcagg cgcaactcct gatatgtttc tggacgaaaa cggaaaagca atacctttct
     9121 ctgaacgtgt aacaaaaggt actgccgttg gtgttccagg cactctgaaa gggctggaag
     9181 aagccttgga taaatgggga acccgttcga tgaagcaatt aattacccct tctattaaac
     9241 tcgctgaaaa aggctttccg attgattctg tgttggcaga tgccatttct gattatcagg
     9301 aaaaactttc acggactgcc gcaaaagatg tatttttacc aaatggcgaa ccgcttaaag
     9361 aaggagatac ccttattcaa aaggatttgg ctaaaacatt taagcttatt cgctccaaag
     9421 gcactaacgc tttttataaa ggaaaattcg ccaagacgct ttctgacact gtccaggatt
     9481 tcggcggatc aatgacagaa aaagatttag aaaattacga cattacaatt gatgaaccga
     9541 tttggggaga ctatcaaggc tatcaaatcg ctactactcc tcctccaagc tccggcggta
     9601 ttttcttatt gcaaatgctg aaaatccttg atgattttaa cctttcacaa tacgatgtcc
     9661 gctcatggga aaaatatcag ctgcttgctg aaacgatgca tttgtcttat gccgaccgtg
     9721 cgtcttacgc aggtgatccc gaatttgtaa atgttcctct caaaggcttg cttcaccccg
     9781 attatattaa agaacgccag caattaatca acctagatca agtgaataaa aaaccgaaag
     9841 ccggtgaccc ttggaaatac caagaaggat cagcaaacta taaacaagtt gaacagccga
     9901 aagacaaagt agaaggccaa acaacccact ttacagttgc tgaccgttgg ggaaatgttg
     9961 tttcctatac aacaacaatc gaacagctgt ttggaacagg tattatggtc cctgattacg
    10021 gagtcatcct aaacaatgaa ttaacggatt ttgatgcgat accaggcgga gctaacgaag
    10081 tacagccaaa caaacggcct ttaagcagca tgaccccgac gattttattt aaggatgaca
    10141 agcctgtcct cactgttgga tctcctggcg gggccacaat tatttcatcc gttttgcaaa
    10201 ccattctcta ccacattgaa tatggtatgg aattaaaagc agctgttgaa gagccgagaa
    10261 tttacacaaa cagcatgagc tcttaccgtt acgaagacgg agttcctaaa gatgtcctca
    10321 gcaagctaaa cgggatgggc cacaaattcg gcacaagtcc ggtggatatc ggaaacgtgc
    10381 aaagcatatc gatcgaccat gaaaacggca cctttaaagg tgtagctgat tcaagcagaa
    10441 acggagcggc gatcggcatt aatttaaaac gtaaataaat aaaaaactgt actcacttca
    10501 aatgagtaca gtttttttat acacatcttt aaaataaaaa ctgacaaacg tctttattct
    10561 gctaatgcag tgtatcagac cagaaatcca acacgtctat cttcatcttt tcatttcgtt
    10621 tatctcatca agaaatgtct gaaacgcact cgtaataaaa aagtctttcc tgtgtataaa
    10681 gacgatctct aagtctttat atgctggcgg cagtttatga atccatacat ttgtacgatg
    10741 ctcggagccg tcaacagcgg actttgggag cagcgccgta cccatcccgg cggaaacacc
    10801 ttttataatg gcctccaatg tgccaaactc tatgattttt ggattgtgta ggcctgcttc
    10861 ctctagtaat cttttgaccc tgtcacgatg agaacagcca gccccaaaaa agagcatcgg
    10921 ctgctgaagc atgtcttctg ccgtctcttc tcgtgatgaa atcaaaacta attcatcatg
    10981 ggaaacatgg agttgtctaa ctgcagcgtg ttcaaccggc ccatatacaa aagcgccatc
    11041 aactttatga tcaagaacct gttgaatcaa atgatgcgta tccgctgtgt tcactgataa
    11101 atccacttca ggaaaacgcc tgaggaagga tgctgcatgc tcaggcagat gcgttaccgc
    11161 cgtcgtttcc agtgatccga tccgcaaagg cccttttggt tgcctgctca ttcgggtcga
    11221 tttttcagct ttgtctaaca gcgataatac ttgatctgca tattgtaaaa gattttctcc
    11281 tgcagcagtc agcttcatcc cccgattcgt tcgatgaaaa agcctgatat tcaaatcttc
    11341 ctcaaggtta tgcactctgg ctgtcacatt cgactgaaca taattcagca tttgggctgc
    11401 tttcgttatg cttccttcgc gggcgacagc ctgaaaaatc tttaaatctc cgctttccac
    11461 gcgctctcac ctgcttgcta tgatgaaaag tgatattggc tatcatattt gttcatttta
    11521 ctcgaagaaa accgctatgt aaaatatgta aagatatgaa aatacaattc aatgaggagg
    11581 cagacagcat gaaagctgta attcacaacg gaaaagccgg ccttcagggg ttatcagtcg
    11641 aggacgttcc atcaacaaag cctggatacg gagaggtaaa ggttaaatta aaatccgcgg
    11701 gcctgaatca tcgtgacttg tttcttatga aaaacaaatc ggaacaagat cctcacatga
    11761 tactgggttc tgacggcgcg ggtatcatcg aagagattgg tgaaggcgtg aaaaatgtta
    11821 ctgttcagac agaagtagtc attttcccga cattgaactg ggatttaaca gagaatgtac
    11881 cacctgtacc tgagattctg ggaggtcctt cggacggaac acttgctgaa tatgtgatca
    11941 ttccttcaca aaatgcaatc aaaaaacctg cttatttatc ttgggaagaa gcgggcgttt
    12001 tacctttatc cgctttaact gcatatcggg ctttgtttac aaaggggcaa ttaaaaaaag
    12061 gcgagcatct attgataccc ggcatcggca gcggtgtggc aacctatgct ttatttatgg
    12121 ctaaggcgat tgaggcaaca gtaagcgtga cctcccgcag tgaggagaaa agaaaaaagg
    12181 cgctgcaatt aggtgctgat tacgcatttg acagctacag caattgggat gagcagttgc
    12241 agggaaaaaa ggcggatgtt gttcttgaca gcataggacc tgctctcttt tcggaatact
    12301 tccgccatgt aaaaccaaat ggccgtattg tcagctttgg ggcaagctca ggggataatc
    12361 tcagttttcc ggtgcgttct ctattctttc ctcaggtcaa tgttttggga acctcgatgg
    12421 gaagcggtga ggaatttcaa gctatgctcg ctttcattga caaacataag ctgcggcctg
    12481 taattgaccg gatatatcct ttagaaaaag catgtgaagc atataaaaga atgcaggaag
    12541 gcagacagtt tggaaacatc gggatcgtaa tggaataaaa aaagaaaccg gctggcagcc
    12601 agaccggttt ctcttatatg ataatcccct ttatttacgg aagaactgaa ctccccatca
    12661 aatatcgatc cacttcacgc gccacttcac ggccttcatt aatcgcccat acgattaagc
    12721 tttggcctct tcttgcatcc cctgcggcga atacaccatc gatatttgtt tgataatccc
    12781 catatgctgc actgattttg ttatttactg aatcaacacc gaactgtttc aacagcggct
    12841 gttctgtgcc ttcaaagccg atagcgataa agacaagctg agcaggccat actttttccg
    12901 ttccaggcag ctcgcggaac tcgtattttc catgctcatt tttcactttt tccatttgga
    12961 tggtatgaag ctctttcagc tttccgtttt tatccgcaac catttttgtc gtttgaatgg
    13021 agtattctct cggatctctt ccgaattttg cttctgcttc ctcgtatgca tattcaagcg
    13081 taaagacgtg tggctgttca ggccacatat tgtcattcgt gcgggctggc ggaagtttcg
    13141 ggtgtttgcc gaattggtgc acgcttttgg ctttttgacg cagagcagta gccacacagt
    13201 cagctcctgt atctccgcct ccgattacga tgacatcctt ccctttggca tcaatgaatt
    13261 gcttgtcttt aaaattagaa tctaaatagc tttttgttgc aagtgtcagg tagtccatcg
    13321 cgtaatggac tccttttgag tcgcgtcctt caattaagag gtcccgctgt ttttgagcgc
    13381 ctgtgcatag gatcacagca tcaaattgct cctttagctc atcagctgta atgtcaacac
    13441 cgatttctgt gttcgtgaca aaatcaattc cttcttgcgt cagcaattta attcggcgtt
    13501 ctacaatgcc cttctcaagc ttcatgtttg gaatgccgta tgttaaaagg ccgcccgctc
    13561 tgtctgagcg ctcaaaaaca gtgacggaat gtcccgcttg attcagctgg tcagcactcg
    13621 ccagtccggc tgggcccgac ccgacgatag ccactttttt gcctgttcgt ttttttggaa
    13681 ttctaggttg aatccaaccg ttctcaaatc ctttatcgat aatggtccgc tcgatgtttt
    13741 taattgatac ggccggatct gaaatcgcta aagtgcatga tccttcacaa ggagcggggc
    13801 atacccgccc tgtgaattca ggaaagttgt ttgttttcaa cagacgttcc aatgcttcct
    13861 tccatctgcc ccggtagaca agatcattcc attcaggaat taagttgtaa atcggacagc
    13921 cggatgtaaa tccgttaatg tccgcaccga tctggcaaaa cggtgtaccg caatccatgc
    13981 accgcgcccc ttgccgtttc gatgcttctt ctgaaaaagg agcagaatat tctttccaat
    14041 cctttaagcg agtgagaggg tcccgctccg caggtttttc tcgtttgatc tccataaatc
    14101 cagttggttt ccccatgttc ctctcccctt ccttactgta ctaccgcttg tttttgtccc
    14161 gatgctgctg tattctgctt tggcttcgtg ttggcctcaa aagcgaacat gatggcttct
    14221 tcatctgata aacctgcagc tttttgctct tggatgcttg cgagcatttg tttatagttt
    14281 ttcggaatga ctttgacgaa ttttttcaca ctgtcttccc attgatcaag cagatcttct
    14341 gctttttggc tgtttgtata cgcagtatgt ctttcaagca ttgctttgat ttgctggatt
    14401 tctttctcat cctctaatga ttcaaataaa atcatctcaa ggttgcattt gcgtttaaac
    14461 gctttgacat cttcggccag tacataagcg attccgccgg acatacctgc cgcaaagttt
    14521 ttgcctactt caccgagaac gacaacgctg ccgccagtca tgtattcaca gccgtggtcg
    14581 ccaatgcctt ctacaactac gttcacaccg ctgtttcgaa cggcaaagcg ttcaccagca
    14641 cgtccgttaa tatatgcttc tccgcttgtc gcaccgtaaa aagccacgtt gccgataatg
    14701 acattgtcat ccgaagcaga gttgaatcct tctggtgact tgacaatgat ttttccgcca
    14761 gaaagccctt ttccgacgta atcatttgag tctccgtcca aataaagcgt catcccttta
    14821 ggaacgaaag ctccaaagct ttggccggct gatccggtaa attgcagctt gattgtatct
    14881 tcaggaagcc cttcatctcc gtagcgcttt gagatttcac tgccggttat cgttccggct
    14941 acacgatttg tattattgat ttcaatcgaa atatcagctt cttttccaga ttcgatggct
    15001 tcttgtacag ccgggagaat tgttgtgata tcaagcgatt gatcaatttt atgattttgc
    15061 ggagattgga atgtccgcac tccttcaggc tgataaagaa gtgtagacaa atcaagctgg
    15121 cctgctttcc agtgcccctt cgcccgttca cttacatgaa gtacatcagt gcggccgatc
    15181 atttcatcaa atgtcttgaa gcctaacgca gccatgtact cacgaacttc ttcggcaatg
    15241 aacagcatat aattcacaat atgatcagga tctcccatga actttttgcg aagctctgga
    15301 ttttgtgtcg ctacaccgac agggcatgta tccaaatggc aggcacgcat catgacacag
    15361 ccgagtacaa ctaacggagc tgttgcaaaa ccaaattctt cggcgccgag caaggcagcc
    15421 atcacaacgt cgcggcccgt cataagcttt ccatctgttt ctaatacaac acggtcacga
    15481 agtccgttca gcattaatgt ttgatgtgct tctgcaaggc caagctccca tggaagccct
    15541 gtatgtttaa tactggtttt cggagaggca cctgtacccc cgtcgtaccc gctgatcaca
    15601 atgacatctg cagtcgcttt ggcaacacct gcagcgattg ttcctacacc tgcttttgac
    15661 accagcttta cgctgattct tgcgtcacgg ttggcatttt tcaaatcgtg gatcagctgg
    15721 gctaaatcct caatcgaata aatgtcatgg tgtggcggag gtgagattaa tccgacacct
    15781 ggcgttgacc cgcggacatc ggcaacccat ggatatactt tgttgccagg cagctgcccg
    15841 ccttcacccg gcttagcacc ttgagccatt ttaatctgca gctcatcagc attgacgagg
    15901 taatggcttt tgacaccaaa ccgtccggat gcaatttgtt tgatcgcact tcttctatca
    15961 tcgccgttct catctggaac aaagcgtttg ggatcttctc cgccttcacc gctgttgctt
    16021 tttcctccaa gacggttcat tgcgattgcc aaagcttcgt gcgcttcctt actcaaggac
    16081 ccgaatgaca tcgcacccgt tttaaagcgt ttgacaatcg attcagcgga ttcaacctcc
    16141 tccaacttca aaggcttgtg gtttccgtca aatgcgaaca agttccgcaa aaatccgatg
    16201 cgttcttcat cagccgcttt tgtatactgt ttaaacagat tgtaatcatt tctgcggcac
    16261 gcccattgca aagtatgaat cgttttcgga ttaaacgcat gatgctctcc gccatttctc
    16321 cattggaagt cacttcccgg ttcaagcgtt ttgctgtaat catcctgata cgcttcccgg
    16381 tggcggcgct gtgcctcttc tgcaattgtt tgtaaatcga tgccgcctag ctgtgatgca
    16441 gtacctgtga aatagcggtc gattacatcg cggctgattc ctactgcctc aaagatttgg
    16501 gcgcctctgt agctttgcac agttgaaatt cccatcttag acatcacttt tacgacgccc
    16561 tctgtaatgc tttttccata tttactgacc gcttcttcat agctgatatc caaacggcct
    16621 tcatcaattt cttgcttgta ggtcgcataa gcgagataag ggttaatcgc atccgcgcca
    16681 taaccgatta atgctgcaaa gtgatgcact tcacgcgctt ctcctgattc cacaataatg
    16741 ctgaccttcg tacgcagccc tttgcggatt aagtgctggt gcagcccgct tactgccaga
    16801 agcggcggaa ttggtgtgag gcgttcgttc atctttttgt ctgataaaat taacaaactt
    16861 acgccttggc tgatggcttt ctctgcttgt gtgaacatgt cctttaatcc gcgttcaaga
    16921 tcctctgaaa acagcacatc aattttttgg ctttttaaat caggatgaac aatcgttttc
    16981 aatgcgtaaa actgttcatt ggataaaaca ggtgtataca gtttaatccg gcgaacattt
    17041 cgttcactcg gatgaagaag atcgccttcc gcaccgagcc aagtcatcgt tgaagtgaca
    17101 agctgctcac gaatcgcgtc gattggcggg ttcgttactt gtgcaaacag ctgtttaaag
    17161 tagttaaaca gtgattgcgc tcggtcagaa agtacagcaa gcggagcgtc attccccatt
    17221 gaaccaaggg gatctttgcc ttctttaata acaggaatta gatacttttg gatatcttca
    17281 tatgtgtatc cgaatgcctt ctggcgagta agaagatcac taaattgttc ttcttctctt
    17341 gactccggat caggattcac ttgtacgagc tcttcttcaa gccatttttg gtacggatac
    17401 tcagttgcaa tttgtgtttt gacttcttca tcggagataa tacggccttc ttccaggtcg
    17461 attaaaagca ttttcccagg ctcaaggcgg tttttatata aaacgttctc ctgttcaact
    17521 tcaataacgc ctacttcaga tgagaaaata atataatcat cttttgtgac ataataacgg
    17581 gccggacgga gaccattccg gtcaaggatc gccccgattt gtttaccgtc agtaaatgaa
    17641 atagctgtcg gtccgtccca aggctccatc agggagctat ggtactcgta gaacgccctt
    17701 ttttccttgg acatatgcgt attttccgtc caaggctctg gaatgagcat cattgccgta
    17761 tgtgccggtt tgcgtccagc catcacaaaa aactcaaatg cgttatccaa aatggaagag
    17821 tcactgccat cagcattgag aatcggcaaa atcttgttta agtcctcacc gaagctttca
    17881 gaaacaaatt gctgctcacg tgctctcatc cagttgatat ttccgcgaag ggtgttaatt
    17941 tcaccattgt gaaccaaata gcggttagga tgcgctcttt cccatgtagg gaatgtattg
    18001 gtactgaagc gtgaatgaac aagcgcaaaa gcagaaacga atgcttcgtc ttgcagatca
    18061 gaataaaatg catcaacctg ttcaggtgtt aaaaggcctt tgtaaacaat ggtctggctt
    18121 gaaagactgg caaaataaaa atcaagacct tccgttactc cccaattttc agcctgttta
    18181 cgaatgacat acaattttcg ttcaaaagat aaattgtcct ttagatcaga acttgcgccg
    18241 ataaatacct gacggacaaa cggacagctt ttttgtgcca ctgttccgat ttttccgaca
    18301 tttacaggta cagttctcca tccaagaacg acttggcctt cttgttcaat cagtgcattg
    18361 atttgctttt caattttttt tctttcatct tctttctgtg agaaaaagac cattcctacc
    18421 ccgtaacgtt ctttttctgg cagattgatg tctttgcact cttttctaaa gaaagcatca
    18481 gggatttgaa ccagtaagcc ggctccgtct cctgtatccg gatcactgcc ttgccctcct
    18541 ctatggtcta gctggcaaag catcttaagt ccttgtttga caatgtcgtg agtctgcttg
    18601 ccctttaagt gtgcatatag gccgattccg catgcatcat gttcaaattc aggacggtag
    18661 agaccttgag cttttggcat ttgattgtac gtcataattc ctctcccccg atcaatttcc
    18721 gataataccg gtcataaaat ctaacaactc tataatcatt gtaggttttc aaaacgatat
    18781 aaacaatata taatttagat caaaagaatc tcaaaatgag atagatggat gtgagacaaa
    18841 catggagctg cgccaactgc gttattttat ggaggtggct gaaagagaac acgtttcaga
    18901 agccgctgat catttgcatg tggcccaatc agcaatcagc agacaaattg ccaatcttga
    18961 agaagaatta aatgtgacct tatttgagcg tgaagggaga aatatcaaac tcacgccaat
    19021 cggaaaagaa tttttgattc atgtgaaaac ggcgatgaaa gccattgatt atgcgaaaga
    19081 gcaaattgat gagtatcttg acccgcatcg cggaacggta aagatcggct ttcctacaag
    19141 cctcgccagc cagcttttgc cgactgtcat ttcagcgttt aaagaagaat atccgcacgt
    19201 cgaatttttg ttgcgccaag gctcctataa gtttctgatt gaagctgtca gaaaccgcga
    19261 tattgatctg gccttattag ggccggtgcc gacgaatttc tctgacataa cgggaaaaat
    19321 attatttact gaaaaaattt acgcgcttgt tccattaaat catccgcttg ctaaacaaaa
    19381 aacggttcat ttaatcgatt tgcgcaacga ccaatttgta ttgttcccgg aaggatttgt
    19441 acttagagag atggcaattg atacttgcaa acaagcaggc tttgctcctc tcgtttccac
    19501 ggagggtgag gatttggatg ctatcaaagg gttagtgtcc gcaggaatgg gcgttaccct
    19561 tctgcctgaa agtacttttg ctgaaacaac acctcgtttt actgtgaaaa ttccaattga
    19621 gttccctcaa gtaaaacgga ctgttggaat cattaaaccg aaaaatagag agcttgcgcc
    19681 ttctgcgaat gatttttatg agtttgtcat tcaatttttc tctaagctgg agcagtatca
    19741 ataaaaaaaa tgaacccgag cttctatata gaagcttcgg gtttttttct gcaaattaat
    19801 ttacaggtaa agaaagatcc acatggcaaa caaatgcttc ttgatcaatt agagctctgt
    19861 ttgtcaattc ctttttcttt tccggttctt gaagatgtac agaagagtaa ttgacgattc
    19921 caaggccgat ttccatccct tttgaatcca tcagccgaac aactgaaccg cttttaaatt
    19981 tccctttaat cttctgtaca ccgtccaggt ataaactcga ttggccgttt gttatttttc
    20041 gtgaacaatc atctgataaa atcatttcac cttccgggcc ggaattaaaa gcgatccatt
    20101 gctccttttg attcaacgga agcgttcctt ctgcttcaaa ataggtgcct tccgcctgtt
    20161 catgaacggc gtggtataaa atatcgccgg catctgcctg acctaggaaa cctttaatgc
    20221 cagacgccat tacgatttta aacgcatcaa gcttagagcg catgccgccg gtgccaacga
    20281 tgctcccagt gtcacctgcg catgcttcga tgtcaggtgt tatttcactc acccgctgta
    20341 tccttttcgc ttctggattt gtgcgcggat tgccgtcata taatccgtct atatctgata
    20401 aaatcacaag catatctgca tcaatcaaac ctgcgacttt tgccgcgagc gtatcattgt
    20461 cgccaaactt gagccgattg acagtaactg tgtcattctc gtttatgatc gggataatgc
    20521 cgcgctcgag cagtacattc attgtattcc tgacattgtt gtatcgatat tcatcagaaa
    20581 aatcgcttct cgtaattaaa atttgggatg cgacatagcc gtgtgccaag aacagctttg
    20641 aataagcctc catcagcaat ccctgaccga ttgaagctga tgcttgtttt tctggaagct
    20701 tctcgggcct ttggataaat ccgagcttcc gatatcctgc cgccactgcg cctgaggaaa
    20761 ccaaaatcac ttcataaccg gcgtctttga gtttgacgac ctggtcgacc aacgcttcta
    20821 attttcgaat gctgatttct ccatgaatgc ttgttaatga actgcttcca atcttcacaa
    20881 cgactctttt catgcttgta tcaggcgtca ctttatcact cctgatagcg gcgctgcagt
    20941 tttttcgata tcttcgctga tttcctttga acgcttagcc gcatgcttta ttgcttgaga
    21001 aatcgcttct ccgccgccgc ttcttttcaa ggcttgcagc cccgctgctg tcgttccgtt
    21061 cggtgacgtg atattatctc ttaagatctc aggatgttct cctgtttcca tgagcatttt
    21121 tgcggcacct aaaagtgtct gtgcgccgat gcttcgagat aactgtttat cgaggcccgc
    21181 ttcctcgcct gtcttttcaa tgaattccat taaataataa aaatacgcgg ggccgctgcc
    21241 tgcaattccg gtgaatatat ccatttgatt ttcttggatt gtatagactt cgcccatgca
    21301 tccgagcaat gcttcggcca gcttcttcaa gtcttccgac acatatttgc caagggcaat
    21361 agctgttgca gaagcgccaa tcatactgga agtgttgggc atcactctga caacaggctg
    21421 ttcattaagc aatgattgtt caataaaaga ggtggttatg ccggcaagga ccgacaatat
    21481 taattgttgg ggttgaatac gtgattttag tgatgacaga gcgttttcgg cgtcttttgg
    21541 cttcattgcc aaaatgagta catccatgtc ttcaatacat agctggttcg gcaaggcgcc
    21601 tttgattcca tattgaagtt caagttcagt taatcgctct gtattgctgc ggtttgtaac
    21661 gcagatgttt tgtttcggga ttttgttggc acgaacgata cctgatatca ttccttccgc
    21721 catagatcct gctcctataa aggctacttt cttttgatca aagatcggta acatctcctt
    21781 tgttcgcttt tttgttcgca ttttcacacg tttaaaatgt taccacgtga ggaaatgatg
    21841 tcaagtttga aggccattat tgatttgtat tgtttctttt cgacaaatat gtataatgaa
    21901 aagcagaaaa cacccggttc atactgctgc gccgggtgtt tgtttctatt aaaagttatc
    21961 tgagagagct ttttcaatca gttttttaca gcgatccagc t
//
