LOCUS       gnlProkkaONKLNMBP_13    2179 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ONKLNMBP_13.
ACCESSION   gnlProkkaONKLNMBP_13
VERSION     gnlProkkaONKLNMBP_13
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 20:14:19
            Original ID  :: gnl|Prokka|ONKLNMBP_13
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 2179
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..2179
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[1:2179]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2..2179
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..2179
                     /SMILES="NC(CCC(=O)O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..2179
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             2..2179
                     /NRPS_PKS="Domain: AMP-binding (1-267). E-value: 2.4e-76.
                     Score: 248.7. Matches aSDomain:
                     nrpspksdomains_ctg13_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (369-438). E-value: 1.1e-25. Score:
                     81.5. Matches aSDomain: nrpspksdomains_ctg13_1_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (452-725). E-value:
                     1.2e-101. Score: 331.5. Matches aSDomain:
                     nrpspksdomains_ctg13_1_Condensation_LCL.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     261.5; E-value: 2e-79)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_1"
                     /sec_met_domain="AMP-binding (E-value: 1.1e-95, bitscore:
                     306.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.5e-18, bitscore:
                     52.7, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 1.4e-94, bitscore:
                     302.6, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLAYVIYTSGSTGQPKGVAVEHRQAVSFLTGMQYQFPLSEDDIV
                     MVKTSFSFDASVWQLFWWALSGASAYLLPPGWEKDSALIVKAIHQEKVTMAHFIPAMLN
                     SFLDQAEMLALGDGTNLKRVFAGGEPLAPRTAARFASVLPQVLLIHGYGPTEATVDAAF
                     YVLDPERDRDHLRIPIGKPVPGARLYVLDPHLAVQPSGVAGELYIAGAGVARGYLNRPA
                     LTEERFLEDPFYPGERMYKTGDVARWLPDGNIEFLGRTDDQVKIRGYRIEPGEIEAALR
                     SIEGVREAAVTVRTDSGEPELCAYVEGLQRNEVRAQLESLLPGYMVPAYMIEMEQWPVT
                     PSGKLDRNALPAPGGAADAETYTAPRNVTEMKLSQLWEDVLKNGPIGIHDNFFDRGGHS
                     LKATALVSRIAKEFDVQVPLKDVFAHPTVEGLATVIREGTDSPYEAIKPTEKQETYPVS
                     SAQKRIYVLQQLEDGGTGYNMPAVLELEGKLNPERMDRAFKELIKRHESLRTAFEQDAG
                     GDPVQRIHDEVPFTLQTTVLGERTEEEAAAAFIKPFDLSQAPLFRAQIVKVSDERHLLL
                     VDMHHIISDGVSVNILIREFGELYNNRKLPALRIQYKDYAVWQEGFKTGDAYKTQEAYW
                     LKQLEGELPVLDLPADHARPPVRSFAGDKVSFTLDQEVASSLHKLARGNGSTLYMVLLA
                     AYTAFLSRLSGQEDIIVGSPIAGRPHKDLEPI"
     aSDomain        5..802
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg13_1_AMP-binding.1"
                     /evalue="2.40E-76"
                     /label="ctg13_1_AMP-binding.1"
                     /locus_tag="ctg13_1"
                     /protein_end="267"
                     /protein_start="1"
                     /score="248.7"
                     /specificity="substrate consensus: Glu"
                     /tool="antismash"
                     /translation="SLAYVIYTSGSTGQPKGVAVEHRQAVSFLTGMQYQFPLSEDDIVM
                     VKTSFSFDASVWQLFWWALSGASAYLLPPGWEKDSALIVKAIHQEKVTMAHFIPAMLNS
                     FLDQAEMLALGDGTNLKRVFAGGEPLAPRTAARFASVLPQVLLIHGYGPTEATVDAAFY
                     VLDPERDRDHLRIPIGKPVPGARLYVLDPHLAVQPSGVAGELYIAGAGVARGYLNRPAL
                     TEERFLEDPFYPGERMYKTGDVARWLPDGNIEFLGRTDDQVKIR"
     aSModule        5..1315
                     /complete
                     /domains="nrpspksdomains_ctg13_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg13_1_PCP.1"
                     /locus_tags="ctg13_1"
                     /monomer_pairings="Glu -> Glu"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       11..70
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg13_1_0001"
                     /evalue="2.90E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg13_1"
                     /protein_end="23"
                     /protein_start="3"
                     /score="35.0"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGQPKGVAVEH"
     CDS_motif       596..685
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg13_1_0002"
                     /evalue="4.10E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg13_1"
                     /protein_end="228"
                     /protein_start="198"
                     /score="57.4"
                     /tool="antismash"
                     /translation="PSGVAGELYIAGAGVARGYLNRPALTEERF"
     CDS_motif       767..832
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg13_1_0003"
                     /evalue="3.80E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg13_1"
                     /protein_end="277"
                     /protein_start="255"
                     /score="41.2"
                     /tool="antismash"
                     /translation="FLGRTDDQVKIRGYRIEPGEIE"
     aSDomain        1109..1315
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg13_1_PCP.1"
                     /evalue="1.10E-25"
                     /label="ctg13_1_PCP.1"
                     /locus_tag="ctg13_1"
                     /protein_end="438"
                     /protein_start="369"
                     /score="81.5"
                     /tool="antismash"
                     /translation="EMKLSQLWEDVLKNGPIGIHDNFFDRGGHSLKATALVSRIAKEFD
                     VQVPLKDVFAHPTVEGLATVIREG"
     aSDomain        1358..2176
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg13_1_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.20E-101"
                     /label="ctg13_1_Condensation_LCL.1"
                     /locus_tag="ctg13_1"
                     /protein_end="725"
                     /protein_start="452"
                     /score="331.5"
                     /tool="antismash"
                     /translation="ETYPVSSAQKRIYVLQQLEDGGTGYNMPAVLELEGKLNPERMDRA
                     FKELIKRHESLRTAFEQDAGGDPVQRIHDEVPFTLQTTVLGERTEEEAAAAFIKPFDLS
                     QAPLFRAQIVKVSDERHLLLVDMHHIISDGVSVNILIREFGELYNNRKLPALRIQYKDY
                     AVWQEGFKTGDAYKTQEAYWLKQLEGELPVLDLPADHARPPVRSFAGDKVSFTLDQEVA
                     SSLHKLARGNGSTLYMVLLAAYTAFLSRLSGQEDIIVGSPIAGRPHKDLEP"
     CDS_motif       1430..1537
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg13_1_0004"
                     /evalue="4.70E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg13_1"
                     /protein_end="512"
                     /protein_start="476"
                     /score="54.4"
                     /tool="antismash"
                     /translation="YNMPAVLELEGKLNPERMDRAFKELIKRHESLRTAF"
     CDS_motif       1736..1801
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg13_1_0005"
                     /evalue="2.50E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg13_1"
                     /protein_end="600"
                     /protein_start="578"
                     /score="32.8"
                     /tool="antismash"
                     /translation="MHHIISDGVSVNILIREFGELY"
     CDS_motif       1832..1861
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg13_1_0006"
                     /evalue="6.20E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg13_1"
                     /protein_end="620"
                     /protein_start="610"
                     /score="15.6"
                     /tool="antismash"
                     /translation="QYKDYAVWQE"
     CDS_motif       2123..2176
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg13_1_0007"
                     /evalue="1.10E-06"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg13_1"
                     /protein_end="725"
                     /protein_start="707"
                     /score="21.1"
                     /tool="antismash"
                     /translation="DIIVGSPIAGRPHKDLEP"
ORIGIN
        1 cggatctctc gcctatgtca tttatacgtc ggggtccacc gggcagccaa aaggggtagc
       61 tgttgagcat cgccaggctg tttcttttct gaccggcatg cagtaccagt ttccgctttc
      121 agaagatgac attgtcatgg tgaaaacctc tttttccttt gatgcgtctg tgtggcagct
      181 gttttggtgg gctctttccg gtgcttcggc gtatctgctt ccgcccggct gggaaaaaga
      241 ctccgcattg atcgtaaaag ccattcatca ggaaaaagtg acaatggctc attttattcc
      301 ggctatgctg aatagctttc tggatcaagc ggaaatgtta gcgcttggtg acgggacaaa
      361 cctaaagcgt gtattcgccg gaggtgaacc gcttgcgccg cgtacggcag cccgttttgc
      421 ttctgtattg ccgcaggtat tattaatcca tggctacggg ccgacagaag caacggtaga
      481 cgcggcattt tacgtattgg atccagaacg ggacagagat catttgcgga ttccgattgg
      541 gaagcccgta cccggtgcgc gtttgtatgt tttagatccg catttagccg tacagccttc
      601 cggtgtcgcc ggcgaactgt acattgccgg agcgggtgtt gccagaggtt atttgaatcg
      661 gccggcatta acggaggagc gttttcttga ggacccgttt tacccggggg aacgcatgta
      721 caaaacagga gacgtggcgc gctggctccc tgacgggaat attgaattcc tcgggcgcac
      781 ggatgatcag gtgaaaatcc gcggctaccg gattgagccg ggagagattg aagcggcact
      841 aagaagtata gaaggtgtaa gagaggcggc cgttaccgta cggacagaca gcggcgagcc
      901 ggaattatgc gcttatgtag aagggctcca aagaaacgaa gtccgagcgc agcttgagag
      961 cctgttgccg ggctacatgg tcccagccta tatgatagaa atggaacagt ggccggttac
     1021 accaagcgga aaactcgacc gaaacgccct gccagctcct ggcggagcgg cagatgcgga
     1081 gacctacacg gcgccgagaa acgtgactga gatgaagctt tctcagctgt gggaggacgt
     1141 gctgaaaaat ggccctatcg ggattcacga taactttttt gaccgcgggg ggcattcctt
     1201 aaaagcaaca gcgcttgtct cacggatcgc caaagaattc gatgtacagg tgccgctaaa
     1261 agatgtgttt gcccatccga cggtagaagg actggctaca gttatccgtg aaggaacgga
     1321 cagtccatat gaagcgatta agcccactga aaaacaggaa acctatccgg tttcctctgc
     1381 ccaaaagcgg atttatgtcc ttcagcagct ggaagacgga gggacaggct acaatatgcc
     1441 ggctgtgtta gagctcgaag ggaagctcaa ccctgaaagg atggacagag ctttcaaaga
     1501 gctgatcaag cgccacgagt cgcttcgaac cgccttcgaa caggacgcag gaggcgatcc
     1561 ggtgcagcgc atccatgacg aggtgccgtt tacgttacag actacagttc tcggcgaacg
     1621 aaccgaagag gaggccgcag ccgcatttat caaaccgttt gatctcagcc aagcgccgct
     1681 gttccgtgcc caaatcgtaa aggtatcaga tgagcggcac ctgttgctgg ttgatatgca
     1741 tcacatcatt tcagacggtg tttccgtcaa cattctgatt cgggaattcg gcgagctgta
     1801 caataatcgg aagcttccgg cactgcgcat tcaatataaa gattatgccg tatggcaaga
     1861 aggatttaaa acaggagatg cgtacaaaac gcaggaggcg tactggctga agcagctcga
     1921 gggcgagctg cctgtgctgg atcttccggc tgatcatgcc cgcccgccgg tgcgaagctt
     1981 cgcgggtgac aaggtctcat ttacgctgga tcaagaggtt gcatcaagcc ttcacaagct
     2041 ggcacgagga aacggaagca cactgtacat ggtgctcctt gcggcttaca ccgcgttctt
     2101 gtcacgctta agcggacagg aagatatcat cgtcggctcg ccaattgccg gccggccgca
     2161 caaggatctt gagccgata
//
